Reagentes Sintéticos

<p>Applications Cyclosporin is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection.A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>

<p>Applications An aldose reductase inhibitor. It is used in treatment of diabetic neuropathy.<br>References Terashima, H., et al.: J. Pharmacol. Exp. Ther., 229, 226 (1983), Kikkawa, R., et al.: Diabetologia, 24, 290 (1983), Kojima, K., et al.: Jpn. J. Ophthalmol., 29, 99 (1985),<br></p>

<p>Applications dTAG-13 is a degradation tag which was tested for its efficiency at depleting FKBP12F36V -MELK(sg3R) and was found to have significantly degraded FKBP12F36V -MELK(sg3R) within 4 hours.Used in the study of cancer research.<br>References Hai-Tsang Huang., eLife, 1-29, (2017)<br></p>

<p>Applications Deshydroxyethoxy Ticagrelor analog of Ticagrelor (T437700) an antiplatelet agent, and preventative in the treatment of heart attacks, myocardial infarction, and other pulmonary diseases.<br>References Zhang, H. et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012);<br></p>

<p>Applications A catalyst used in wide range of polymerization reaction. It has been used as a mild Lewis acid catalyst for the stereoselective Diels-Alder reaction as wel as in a Ziegler-Natta type catalyst system for the polymerization of 1,3-butadiene.<br>References Gong, D. et al.: Polymer, 50, 2826 (2009); Gorman, D. B. et al.: Chem. Comm., 1, 25 (2004);<br></p>

<p>Applications Larixol, is an intermediate in the synthesis of larixyl acetate. This compound is also found to have antibacterial activity and high potential antioxidant activity.<br>References Prideevech, P., et al.: Chiang Mai J. Sci, 40, 214 (2013)<br></p>

<p>Applications 1,1-Bis(hydroxymethyl)cyclopropane is used in the synthesis of morphine alkaloids. It also serves as an inhibitor of 5-lipoxygenase.<br>References Evans, D.A. et al.: Tetrahedron Lett., 23, 285 (1982); Arai, Y. et al.: J. Med. Chem., 26, 72 (1983);<br></p>

<p>Applications 5-Methyl-4-nitroimidazole can cause mutations with Klebsiella pneumonia and Salmonella typhimurium.<br>References Voogd, C.E., et. al.: Mutat. Res. Genet. Tox. Testing, 66, 207 (1979); Kramers, P.G.N.: Mutat. Res. Genet. Tox. Testing, 101, 209(1982)<br></p>

<p>Stability Hygroscopic<br>Applications 1,4-Pentanediol is a useful synthetic intermediate. It was used in the preparation of poly(ortho ester). 1,4-Pentanediol on dehydration in water at 573K yields five-membered ether, 2-methyltetrahydrofuran.<br>References Heller, J., et al.: J. Controlled Release, 78, 133 (2002); Yamaguchi, A., et al.: green Chem., 11, 48 (2009)<br></p>

<p>Applications It is an Olefin Metathesis Catalyst for cis-selective ring-opening metathesis polymerization and Z-Selective Olefin Metathesis.<br></p>

<p>Applications Blebbistatin blocked myosin II-dependent cell processes. It blocks cell blebbing rapidly and reversibly. Blebbistatin also rapidly disrupted directed cell migration and cytokinesis in vertebrate cell. Blebbistatin blocks both blebbing and cytokinesis at 50-100µM.[Blebbistatin:a]D= -103 (c= 1.21 CHCl3)(-)-1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2,3-b]-7-methylquinolin-4-oneBlebbistatin is a selective inhibitor of nonmuscle myosin II; Blebbistatin inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly. Blebbistatin rapidly and reversibly blocks cell blebbing, and disrupts directed cell migration and cytokinesis in vertebrate cells.<br>References Straight, A.F., et al.: Science, 299, 1743 (2003), Duxbury, M.S., et al.: Biochem. Biophys. Res. Commun., 313, 992 (2004), Kovacs, M., et al.: J. Biol. Chem., 279, 34 35557 (2004)<br></p>

<p>Applications Metol is the hemisulfate salt of 4-Hydroxy-N-methylaniline (H918925), used to synthesize arylidene amino azolones with anticancer activity. It is also used to prepare N-(4-hydroxyphenyl)retinamide analogs with antitumor and apoptosis-inducing activities.<br>References Subtel’na, I., et al.: Bioorg. Med. Chem., 18, 5090 (2010); Mershon, S., et al.: Bioorg. Med. Chem. Lett., 17, 836 (2007)<br></p>

<p>Applications A minor antimicrobial used in veterinary medicine.<br>References Dowling, P.M., et al.: Antimicrob. Ther. Vet. Med., 285 (2006), 4th Edition,<br></p>

<p>Applications Toceranib Phosphate is a useful compound in the treatment of chemotherapy-induced diarrhea.<br>References Conte, L. A.: U.S. Pat. Appl. Publ. (2020), US 20200345687 A1<br></p>

<p>Applications MK-0822 is a newly developed bone-targeting dual action pro-drug for osteoporosis and bone metastasis. It is also an inhibitor of cathepsin K, an enzyme involved in bone resorption.<br>References Arns, S., et al.: Bioorg. Medn. Chem., 20, 2131 (2012); Cusick, T., et al., J. Bone. Mineral. Rsch., 27, 524 (2013);<br></p>

<p>Applications Used for preparation of antidiabetic agents comprising antiinflammatory or analgesic drugs.<br>References Nemoto, H., et al.: J. Med. Chem., 38, 1673 (1995),<br></p>

<p>Applications (2R,3R)-rel-2,3-Dihydroxy-2-methylbutanoic Acid Sodium Salt, is the 3R-isomer of (2R,3S)-rel-2,3-Dihydroxy-2-methylbutanoic Acid (D453150); a synthetic organic compound used in studying the synthesis of chiral molecules from non-chiral reactants.<br>References Chenchaiah, P., et al.: J. Chem. Soc., Chem. Commun., 8, 436 (1982)<br></p>

<p>Applications (R)-(+)-Citronellic Acid is an oxidized derivative of Citronellal (C525025), a monoterpene compound that is formed by the metabolism of plants.<br>References Brito, R.G., et al.: J. Nat. Med., 66, 637 (2012);<br></p>

<p>Applications Ammonium thiocyanate is used in synthetic chemistry as a thiocyanation reagent. Ammonium thiocyanate is also a knwn plant poison and is used as a weed eradicant in the agricultural industry.<br>References Harvey, R.: Agronomy J.: 23, 944 (1931); Sandhoff, A. &amp; Skinner, C.: Soil Sci., 48, 287 (1939); Wu, G., et al.: Tetrahedron Lett., 46, 5831 (2005)<br></p>

<p>Applications Bromocyclopentane, is an organic reagent that can be used as both the starting material and an intermediates in the chemical synthesis. It can be used as an starting material in the synthesis of Glycopyrrolate Bromide (G656980), which is a is a medication of the muscarinic anticholinergic group.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kaltiala, E., et al.: J. Pharm. Pharmacol., 26, 352 (1974), Kongsrud, F., et al.: Acta Anaesthesiol. Scand., 26, 620 (1982),<br></p>

<p>Applications Gepirone is an antidepressant and anxiolytic of the azapirone class. It acts as a selective partial agonist of the 5-HT1A receptor.<br>References Sharp, T., et al.: Brit. J. Pharm., 96, 283 (1989); Dunn, R., et al.: Eur. J. Pharm., 169, 1 (1989)<br></p>

<p>Applications Sodium Tetrachloroaurate(III) Dihydrate, is an essential chemical compound used in chemical synthesis as gold catalyst.<br></p>

<p>Stability Hygroscopic<br>Applications Methyltrioctylammonium chloride is a tetraalkylammonium salt that acts as a cationic surfactant. Methyltrioctylammonium chloride is also used as a phase transfer catalyst in the epoxidation of 1,4-diallyloxybutane to 1-allyloxy-4-glycidyloxybutane.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bischoff, R. &amp; McLaughlin, L.: Analyt. Biochem., 151, 526 (1985); Dadfarnia, S., et al.: Talanta, 79, 1061 (2009); Kaczmarczyk, E., et al.: J. Mol. Catal. A, 235, 52 (2005)<br></p>

<p>Applications 5,6-Dehydropregabalin is an impurity of the anticonvulsant, Pregabalin (P704800).<br>References Dousa, M, et al.: J. Pharmac. Biomed. Anal., 53, 717 (2010);<br></p>

<p>Stability Light Sensitive<br>Applications Used primarily as a reagent in trifluoromethylation reactions.<br>References Fantasia, S. et al.: J. Org. Chem., 75, 1779 (2010);<br></p>

<p>Applications Hydroxymethyl Ivacaftor is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.<br>References Clancy, J. et al.: Am. J. Resp. Crit. Care. Med., 186, 593 (2012)<br></p>

<p>Applications L-Homoserine Lactone Hydrobromide is a reactant in the synthesis of tritium labeled and photoactivatable N-acyl-L-homoserine lactones.<br>References Jakubczyk, D., et. al.: Eur. J. Org. Chem., 592, 2014 (2014)<br></p>

<p>Applications Barium chloride dihydrate is used in the synthesis of 2R, 3S-Dihydroxy-4-oxo-butanoic Acid (D450800).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications A useful phase transfer catalyst.<br></p>

<p>Applications (R)-2-Aminobutyramide Hydrochloride is used as a reagent in the synthesis of a new class of 2-[(arylalkyl)amino]alkanamide derivatives which have anticonvulsant activity.<br>References Pevarello, P., et al.: J. Med. Chem., 41, 579 (1998)<br></p>

<p>Stability Moisture Sensitive<br>Applications 2-Methylbutyl Chloroformate is an ester of chloroformic acid and is used as an intermediate in the synthetic preparation of pharmaceutical goods and inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dupuy, W.E., et al.: J. Chem. Soc. Phy. Org. Chem., 1, 74 (1973);<br></p>

<p>Stability Hygroscopic<br>Applications Bis(tributylammonium) Pyrophosphate is an phosphorylating reagent used in the synthesis of phosphorylated deoxynucleosides.<br>References Santner, T. et al.: Bioorg. Med. Chem, 20, 2416 (2012); Sun, D. et al.: ChemMedChem, 4, 1649 (2009)<br></p>

<p>Stability Shock Sensitive<br>Applications 2,2-Diphenyl-1-picrylhydrazyl is a stable free radical molecule most commonly used as a tool to monitor chemical reactions involving radicals, most notably in antioxidant assay.<br>References Suzhukim K., et al.: J. Org. Chem., 78, 2301 (2013); Chen, Z., et al.: Food. Chem., 138, 414 (2013); Chatterjee, S ., et al.: Advan. BIo. Res., 3, 109 (2012);<br></p>

<p>Applications 5-Bromo-2-thiophenecarboxaldehyde is used in biological studies as anti-inflammatory and anti-tumor activity of the marine mangrove Rhizophora apiculata.<br>References Prabhu, V.V., et al.: J. Immunotoxicol., 9, 341 (2012);<br></p>

<p>Applications Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene. A synthetic intermediate in the preparation of CNS depressants.<br>References Mungur, R., et al.: J. Biomed. Biotechnol., 2, 198 (2005), Young, J., et al.: Bioorg. Med. Chem. Lett., 17, 5310 (2007),<br></p>

<p>Applications Hydrazine Hydrate used as a reactant in the cyclizations of pyridinones. It is also used in the study of nanocrystal semiconductors, participating in the functionalization and passivation of surface states.<br> E0<br>References Smolyar, N. et al.: Rus. J. Org. Chem., 44, 1205 (2008); Traub, M. et al.: J. Am. Chem. Soc., 130, 955 (2008);<br></p>

<p>Applications (+)-MK 801 Hydrogen Maleate acts as an NMDA receptor antagonist. It is selective and potent, but noncompetitive, used in various ischemia treatments.<br>References Ma, J. et al.: Hippocamp., 22, 2208 (2012); Cao, Z. et al.: Toxicol. Sci., 130, 362 (2012);<br></p>

<p>Stability Moisture Sensitive<br>Applications Tributylphenyltin acts as a reagent for the synthetic preparation of tetrahydroisoquinolines and SAR as potential HIV-1 antivirals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Swidorski, J. J., et al.: Bioorg. Med. Chem. Lett., 26, 160 (2016)<br></p>

<p>Stability Moisture Sensitive<br>Applications 4-Nitrophenyl Chloroformate is an ester of chloroformic acid used in the immobilization of enzymes and other biomolecules.<br>References Scouten, W.H, et al.: Ann. N.Y. Acad. Sci., 750, 391 (1995); Mikulec, L.J. et al.: J. Biomed. Mat. Res., 32, 203 (1996);<br></p>

<p>Applications Potassium Hexacyanoferrate(III) is used in the synthesis of nanocomposite photoadducts.<br>References Rather, M. et al.: Synth. Metal., 179, 60 (2013);<br></p>

<p>Applications 6-O-α-D-Maltosyl-β-cyclodextrin is an additive to improve the solubility of quetiapine.<br>References Ogawa, N., et. al.: Chem. Pharm. Bull., 31, 809 (2013)<br></p>

<p>Applications A biphosphonate bone resorption inhibitor.<br>References Fraser, W.D., et al.: Postgrad. Med. J., 73, 496 (1997),<br></p>

<p>Applications Hydrazine Dihydrochloride (cas# 5341-61-7) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.<br>References Bacchi, C.J., et al.: Science, 210, 332 (1980); Haegele, K.D., et al.: Clin. Pharmacol. Ther., 30, 210 (1981); Meyskens, F.L., et al.: Clin. Cancer Res., 5, 945 (1999);<br></p>

<p>Applications Decaborane is a useful building block mostly used in the preparation of carboranes. On its own, Decaborane is able to undergo reduction via acetate as a neat liquid.<br> E0<br>References Marsh, A. V.; et al.: Angew. Chem. Int. Ed., 57, 10640 (2018); Kelley, S. P.; et al.: ACS Omega, 3, 8491 (2018).<br></p>

<p>Applications A novel pancreatic lipase inhibitor for the treatment of obesity in both diabetic and non-diabetic patients.<br>References Yamada, Y. et al.: Horm. Metab. Res., 40, 539 (2008); Kopelman, P. et al.: Int. J. Obes., 31, 494 (2007); Kopelman, P. et al.: Obesity, 18, 108 (2010);<br></p>

<p>Applications 2-Hydroxypropyl-β-cyclodextrin (HBC) is a widely used modified cyclodextrin, the lipophilic cavity formed by 7 glucose units. Drug solubility in water is greatly enhanced by complexing with 2-Hydroxypropyl-β-cyclodextrin. The number of 2-hydroxypropyl ranges from 5 to 14.<br>References Pitha, J. et al.: Int. J. Pharmacol., 29, 73 (1986); Frijink, H.W. et al.: Pharm. Res., 8, 380 (1991);<br></p>

<p>Applications α-Arbutin is a component used in the skin-whitening cosmetics.<br>References Magnusson, B., et al.: J. Invest. Dermatol., 52, 268 (1969), Goodwin, B., et al.: Contact Dermatitis, 7, 248, (1981), ,Itoh, M., et al.: J. Dermatol., 9, 223 (1982), Sugimoto, K., et al.: Biol. Pharm. Bull., 24, 510 (2004),<br></p>

<p>Applications Mercury(II)Oxide is used in the synthesis of a mercury based superconductor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shimoyama, J. et al.: Phys. Super. Appl., 224, 1 (1994); Maignan, A. et al.: Phys. C. Super., 243, 233 (1995);<br></p>

<p>Applications Cobalt Carbonyl is a metal carbonyl used as a reagent and catalyst in organometallic chemistry and organic synthesis. Cobalt Carbonyl is commonly used as a hydroformylation catalyst for the conversion of alkenes to aldehydes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mirbach, M. et al.: J. Am. Chem. Soc., 103, 7594 (1981); Haukka, M. et al.: J. Mol. Cat. A Chem., 102, 79 (1995); Haumann, M. et al.: Catal. Tod., 79, 43 (2003);<br></p>

<p>Applications A dihydropyridine calcium channel blocker.<br>References Ikeda, K., et al.: Oyo Yakuri, 44, 433 (1992), Hosono, M., et al.: J. Pharmacobio-Dyn., 15, 547, (1992), Ishii, M.: Japan Pharmacol. Ther., 21, 59 (1993),<br></p>

<p>Applications Methyl (S)-N-Tritylaziridine-2-carboxylate (cas# 75154-68-6) is a compound useful in organic synthesis.<br></p>

<p>Applications Ethyl 3-Furoate is the ethyl ester derivative of 3-Furoic Acid (F863770) and is used as a reagent in the synthesis of disubstituted furan derivatives which exhibit antidiabetic activity. Also used as a reagent in the synthesis of sulfonylfuran ureas as selective endothelial lipase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Babu, S.P., et al.: Pharma Chem., 4, 2178 (2012); Goodman, K.B., et al.: Bioorg. Med. Chem. Lett., 19, 27 (2009)<br></p>

<p>Applications A PDE7 inhibitor that has acceptable selectivity for in vivo studies. Potent PDE-7 inhibitor.<br>References Smith, S.J., et al.: Mol. Pharmacol., 66, 1679 (2004)<br></p>

<p>Applications Hepes<br></p>

<p>Applications Sodium Phosphate Monobasic Monohydrate is often used in foods and in water treatment. it can be used as a buffer to adjust pH. In medicine, it is sometimes used as a stimulant laxative before certain operations and medical procedures.<br>References Krajewska, B., et al.: Biocat. Biotrans., 23, 225 (2005); Aliabadi, H., et al.: Am. J. Health-System Pharm., 65, 441 (2008); Henderson, J., et al. Gastrointestinal endoscopy 42, 238 (1995)<br></p>

<p>Applications Adamantoic Acid is an inhibitor of chorismate mutase activity and hydroxyphenylpyruvate synthase. It inhibits TTR conformational changes facilitating amyloid fibril formation.<br>References Baures, P. et al.: Bioorg. Med. Chem., 6, 1389 (1998); Christopherson, R. et al.: Biochem., 24, 1116 (1985); Chao, Herbert S. &amp; Berchtold, G.: Biochem., 21, 2778 (1982)<br></p>

<p>Applications Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.<br>References Lindner, E., et al.: Arzneim.-Forsch., 28, 284 (1984), Hoever, G., et al.: J. Med. Chem., 48, 1256 (2005), Lai, S., et al.: Eur. J. Clin. Microbiol. Infect. Dis., 24, 5831 (2005),<br></p>

<p>Applications Sulbactam Pivoxil is a prodrug of the semi-synthetic β-lactamase inhibitor Sulbactam (S699195).<br>References Foulds, G. et al.: Curr. Chemother. Infect. Dis., Proc. Int. Congr. Chemother., 11, 353 (1980); Pei, Q. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 879, 2000 (2011);<br></p>

<p>Applications N-(2-Carboxy-2-hydroxycaproyl)hydrazobenzene is an impurity in the synthesis of pheylbutazone (P319570) derivatives.<br>References Fricoteaux, R., et al.: J. Pharm. Biomed. Anal., 7, 1585 (1989), Segrestaa, J., et al.: Chem. Pharm. Bull., 50, 744 (2002),<br></p>

<p>Stability Unstable in Solution, Air Sensitive<br>Applications An antirheumatic agent.<br>References Masutani, K., et al.: Clin. Nephrol., 70, 464 (2008), Kobata, Y., et al.: Modern Rheumatol., 19, 629 (2009), Oki, K., et al.: Inflam. Res., 58, 571 (2009),<br></p>

<p>Applications 5-Hydroxymethyl-2-furoylglycine can be used as analyte for analytical and biological studies of determination of metabolites of 5-​hydroxymethylfurfural in human urine after oral application.<br>References Hardt-Stremayr, M., et al.: J Sep Sci., 36, 670-676 (2013)<br></p>

<p>Applications An impurity of the anti-convulsant (S)-Pregabalin (P704790).<br>References Lin, S. et al.: J. Liq. Chrom. Rel. Technol., 19, 2699 (1996); Sripathi, S. et al.: ARKIVOC, 10, 266 (2010);<br></p>

<p>Applications Sodium Chlorite is used as a bleaching agent for cotton textiles.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shenai, V.A., Pai, S.M.: Textile Dyer Printer, 3, 153 (1969)<br></p>

<p>Applications Zinc Chloride is a common chemical reagent used in organic syntheses, often alkylation reactions.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Huo, S. et al.: Org. Lett., 5, 423 (2003);<br></p>

<p>Applications Rhodium(III) chloride is often used in synthetic chemistry as a hydrogenation catalyst. Rhodium(III) chloride is also used to make transition metal complexes, some of which are used as reagents in the decarbonylation dehydration reactions of fatty acids to alkenes.<br>References Foglia, T. &amp; Barr, P.: J. Am. Oil Chem. Soc., 53, 737 (1976); Hillis, J. &amp; DeArmond, M.: J. Lum., 4, 273 (1971); James, B. &amp; Rempel, G.: Can. J. Chem., 44, 233 (1966)<br></p>

<p>Applications One of the panels of serum metabolic biomarkers for detecting and diagnosing cancer, especial ovarian cancer.<br>References Broadhurst, D., et al.: Metabolomics, 2, 171 (2006), Karim, S., et al.: Plant Mol. Biol., 64, 371 (2007), Shi, J., et al.: Nat. Biotechnol., 25, 930 (2007),<br></p>

<p>Applications 3,3-Diphenylpropylamine is a metabolite of Prenylamine (P712800). 3,3-Diphenylpropylamine showed antiextensor effects as well as neuroexcitatory effects and antagonized barbital-induced loss of the righting reflex.<br>References Hornke, I. et al.: Arzneim.-Forsch., 20, 791 (1970); Remberg, G. et al.: Biomed. Mass Spec., 4, 197 (1977); Helke, C. et al.: Eur. J. Pharmacol., 48, 231 (1978);<br></p>

<p>Applications 4-Aminobutylcarbamic Acid tert-Butyl Ester is used in the synthesis of iron chelators expressing antitumor activity. Also used in the synthesis of iron oxide nanoparticles which are used in cellular and small animal imaging.<br>References Corce, V. et al.: Bioconj. Chem., 25, 320 (2014); Stanicki, D. et al., J. mat. Chem. B. Mat. Biol. Med.: 2, 387 (2014);<br></p>

<p>Stability Light Sensitive<br>Applications (Z)-Mycophenolic acid is the Z-isomer of Mycophenolic acid (M831500), an antibiotic drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Stability Light Sensitive, Moisture Sensitive<br>Applications Mercury(II) thiocyanate (cas# 592-85-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications Phosphoric Acid is used in various chemical processes as a phosphorylating compound. It is involved in the hydrolysis via phosphorylation of nanocrystals to obtain high-aspect-ratio cellulose nanocrystals. Also used in the synthesis of lithium-ion cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Camarero E. et al.: Biomacromol., 14, 1223 (2013); Meligrana, G. et al.: J. Power. Sources., 160, 516 (2006);<br></p>

<p>Applications Labelled DL-Homocystine is used in the synthesis of potential antitumor agents through inhibition of L-asparagine. There is growing clinical evidence that elevated homocysteine levels are associated with an increased risk of venous and arterial thrombosis.<br>References Brynes, S. et al.: J. Pharm. Sci., 67, 1550 (1978); Lauricella, A. et al.: Thromb. Res., 107, 75 (2002);<br></p>

<p>Stability Moisture Sensitive<br>Applications n-Undecanoyl Chloride is an analog of Heptanoyl Chloride (H281235), which is used in the synthesis of novel class of 2-Aminopyrimidines as CDK1 and CDK2 inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Samanta, R., et al.: Org. Lett., 14, 5518 (2012); Sabbah, M., et al.: Bioorg. Med. Chem., 20, 4727 (2012)<br></p>

<p>Stability Desiccate and Store at -20°C<br>Applications Kifunensine is an alkaloid produced by the fungus, Kitasatosporia kifunense, and has been shown to be a weak inhibitor of aryl mannosidase. It is a unique oxamide derivative of mannojirimycin and a potent inhibitor of the glycoprotein processing enzyme mannosidase I. Kifunenesine is ineffective in inhibiting either mannosidase II or the endoplasmic reticulum (ER) a-mannosidase. It also possesses immunomodulating properties based on chemical, physicochemical and x-ray crystallographic analysis.When tested in cell culture using influenza virus-infected MDCK cells, kifunensine, at 1 mg/ml or less, caused almost complete inhibition of complex chain formation with the accumulation of Man9(GlcNAc)2. Thus, kifunensine was proven to be 50 to 100 times more effective than deoxymannojirimycin.Ph<br>References Iwami, M., et al.: J. Antibiotic., 40, 612 (1987); Elbein, A.D., et al.: J. Biol. Chem., 265, 15599 (1990); Elbein, A.D., et al.: Archives of Biochem &amp; Biophys., 288, 1, 177 (1991); Kayakiri, H., et al.: Chem. Pharm. Bull., 39(6), 1378 (1991)<br></p>

<p>Stability Hygroscopic<br>Applications (S)-3-Aminoazepan-2-one hydrochloride (cas# 26081-07-2) is a useful research chemical.<br></p>