Álcoois

Applications Used in the preparation of pyridine analogues of vitamin B1.
References Tracy, A. & Elderfield, R.; J. Org. Chem., 6, 54 (1941); Tracy, A. & Elderfield, R.; Science, 92, 180 (1940)

Applications 2,4-Dimethyl-2-pentanol is used in the development of two reliable aqueous solubility models ASMS (aq. soly. based on mol. surface) and ASMS-​LOGP (aq. soly. based on mol. surface using calcd. log P (ClogP).
References Wang, J., et al.: J. Chem. Inf. Model., 47, 1395 (2007)

Applications 3-[benzyl(methyl)amino]propane-1,2-diol (cas# 60278-98-0) is a useful research chemical.

Applications 3-Aminocyclohexanol_x000D_(cis/trans mixture) (cas# 6850-39-1) is a compound useful in organic synthesis.

Applications 1,3-Diamino-2-propanol is a reagent used in the quantitative fluorescent detection of pyrophosphate with quinolin-ligated dinuclear zinc complexes.
References Mikata, Y., et al.: Inorg. Chem., 52, 10223 (2013)

Applications 4,4'-Thiobisbenzenethiol acts as a reducing agent, and affects the catalytic activity of caspase-3 protein.
References Okun, I. et al.: J. Biomol. Screen., 11, 694 (2006);

Applications 4-(Benzyloxy)cyclohexanol (cis / trans mixture) (cas# 2976-80-9) is a compound useful in organic synthesis.

Applications 2,4-Dimethylphenol is used both as a pesticide to ward of insects or other common pests from crops from crops as well as in the synthesis of anti-oxidant compounds due to the phenol moiety in the structure.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Liu, B. et al.: J. Agri. Chem., 58, 2673 (2010); Guillen, M. et al.: J. Agri. Chem., 47, 3016 (1999); Guillen, M. et al.: J. Agri. Chem., 46, 1276 (1999); Kim, S. et al.: J. Agri. Chem., 59, 4570 (2011)

Applications (S)-2-Amino-3-(4-aminophenyl)propan-1-ol is derived from (2S)-2-Amino-3-(4-nitrophenyl)-1-propanol (A618365), which can be used as an intermediate in the synthesis of various pharmaceutical compounds. It is used in the preparation of a new series of 2-substituted thiazole carboxamides as potent inhibitors of Akt kinases.
References Shaohua, Ch., et al.: Bioorg. Med. Chem. Lett., 22, 1208 (2012);

Stability Air Sensitive, Unstable in DMSO
Applications 2,2-DIMETHYL-2,3-DIHYDRO-1-BENZOFURAN-5-THIOL (cas# 1248920-72-0) is a useful research chemical.

Applications 1,3-Dihydro-1-hydroxy-2,1-benzoxaborol-5-ol is used as a reagent in the synthesis of P4-benzoxaborole-substituted macrocyclic inhibitors of HCV NS3 protease.
References Ding, C.Z., et al.: Bioorg. Med. Chem. Lett., 20, 7317 (2010)

Applications Used in the preparation of bicyclic substituted indole derivatives as steroid hormone nuclear receptor modulators.

Applications 7-Octyn-1-ol is used in the synthesis of the sex pheromone of the citrus leafminer, Phyllocnistis citrella.
References Ando, T., et al.: Agric. Biol. Chem., 49, 3633 (1985), Beevor, P., et al.: J. Chem. Ecol., 12, 1 (1986), Kerr, D., et al.: J. Med. Chem., 33, 1958 (1990), McElfresh, J., et al.: Ecology, 82, 3505 (2002),

Applications Hydroxybutenolide can be used as reactant/reagent for synthetic preparation for enantioselective preparation of hydroxy-GR24 stereoisomers via contra-biomimetic nucleophilic cyclization.
References Morris, J. C., and McErlean, C. S. P.: Org. Biomol. Chem., 14, 1236-1238 (2016)

Applications 1-(2H-1,3-benzodioxol-5-yl)prop-2-en-1-ol (cas# 5208-87-7) is a useful research chemical.

Applications 2-[2-(2-Propynyloxy)ethoxy]ethanol is a reactant used in the preparation of divalent ligands based on 3-deoxy-4-thiolactose as inhibitors of E. coli β-galactosidase.
References Cagnoni, A.J., et. al.: Org. Biomol. Chem., 11, 5500 (2013)

Applications 1-EICOSANETHIOL (cas# 13373-97-2) is a useful research chemical.

Applications 2-(ethylsulfanyl)ethane-1-thiol (cas# 26750-44-7) is a useful research chemical.

Applications 1,3,5-Pentanetriol, is an intermediate for the synthesis of various pharmaceutical compounds, including inhibitors and Antagonist.
References Utech, T., et al.: Euro. J. Med. Chem., et al.: 46, 2157 (2011);

Applications 3-[(Dimethylamino)carbonyl]phenol can be used in the synthesis of novel purine and bicyclic pyrimidine, which are factor Xa inhibitors, and also have high selectivity over thrombin and trypsin.
References Buckman B. O., et al.: Bio. Med. Chem. Let., 8, 2235 (1998)

Stability Hygroscopic
Applications 6-Amino-2-hydroxymethyl Hexan-1-ol (cas# 125162-81-4) is a compound useful in organic synthesis.
References Rubina, A., et al.: Anal. Biochem., 325, 92 (2004),

Applications 1,1,2,2-tetraphenylethane-1,2-diol (cas# 464-72-2) is a useful research chemical.

Applications 3,3-Dimethyl-2-butanol is used as a reagent in the synthesis of 2,4-dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists. 3,3-Dimethyl-2-butanol is also used in the preparation of dihydropyrrole derivatives containing N-sulfanyl, sulfinyl, and sulfonyl moieties which have insecticidal activity.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ito, M., et al.: Bioorg. Med. Chem., 11, 489 (2003); Micheli, F., et al.: Bioorg. Med. Chem., 11, 171 (2003)

Applications 1,3,2-Dioxathiolane 2,2-Dioxide is an alkylating agent with carcinogenic activty.
References Van Duuren, B.L. et al.: J. Nat. Cancer Inst., 53, 695 (1974);

Applications O-Benzylmetaraminol is an impurity of M225565.

Applications (R)​-​(-​)​-​1,​3-​Butanediol is a chiral reagent used in the synthesis of pharmaceuticals including the preparation of (-​)​-​tarchonanthuslactone, a δ-​lactone skeleton based compound with antiroliferative activity on cancer cell.
References Novaes, L. et al.: ChemMedChem., 10, 1687 (2015);

Applications 5-Hexen-1-ol is a volatile organic compound that can be found in Brazilian chilli peppers (Capsicum spp.).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bogusz, S.Jr., et al.: Food Res. Int., 48, 98 (2012)

Applications (1R,2R)-rel-trans-1,2-Cyclopentanediol is a building block for the synthesis of chiral phosphine ligands. It can also be used to prepare benzoquinolines and benzoindoles via heterocyclization of naphthylamines with diols catalyzed by iridium chloride/BINAP
References Kündig, E., et al.: Helv. Chim. Acta, 77, 421 (1994); Aramoto, H., et al.: J. Org. Chem., 74, 628 (2009)

Applications Asenapine Phenol is a research reagent used to study effect on DNA oxidation
References Bao, L.L., et al.: ChemMedChem, 11, 1617 (2016)

Applications 3-Amino-4-hydroxybenzenesulfonamide is a reagent used to synthesize antagonists for somatostatin receptor subtype 5 (SST5R). It also has utility in dye applications.
References Martin, R. E., et al.: J. Med. Chem 50, 6291 (2007); Sokolowska-Gajda, J. et al.: Dyes Pigm. 30, 1 (1996)

Applications 3,4-Diaminophenol (cas# 615-72-5) is a useful research chemical.

Applications 2-{[2-(Dimethylamino)ethyl]methylamino}ethanol is a reagent in the preparation of diamino(aminoalkoxy)quinazolines.
References Liu, F., et al.: J. Med. Chem., 53, 5844 (2010);

Stability Unstable in aqueous media
Applications 1H-indazol-1-ylmethanol (cas# 1006-29-7) is a useful research chemical.

Applications 2-(2-Cyclopenten-1-yl)-phenol is an intermediate used in the synthesis of (S)-Penbutolol Sulfate (P220505), which is an isomer of Penbutolol (P220500), a β-adrenoceptor antagonist. Antihypertensive.
References Lassen, J.B.: Eur. J. Pharmacol., 47, 351 (1978), Lund, J., et al.: Acta Pharmacol. Toxicol., 51, 351, (1982),

Applications 2-Cyclohexen-1-Ol (cas# 822-67-3) is a useful research chemical.

Applications Cyclohexane is a general organic chemical solvent. It is also used as a precursor to the synthesis of nylon.
References Hiroshi O. et al.: J. Memb. Sci., 105, 51 (1995); Rekharsky, M.V. et al.: J. Am. Chem. Soc., 124, 12361 (2002);

Applications (S)-Pyroglutaminol (cas# 17342-08-4) is a compound useful in organic synthesis.

Applications 3,6-Dimethyl-3-heptanol (cas# 1573-28-0) is a compound useful in organic synthesis.

Applications 23-Azido-3,6,9,12,15,18,21-Heptaoxatricosan-1-ol is used in the synthesis of heterobifunctionalized oligo(ethylene glycol) linkers for use in drug delivery.
References Goswami, L. et al.: Org. Biomol. Chem., 11, 1116 (2013);

Applications 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)amino]ethanethiol is used in the preparation of fluorescent N/S acyl derivatives.
References 2-[(7-Nitro-2,1,3-benzoxadiazol-4-yl)thio]ethanamine

Applications 2-[(Tributylstannyl)methyl]-2-propen-1-ol is a useful reagent for organic synthesis.

Applications 1-Heptanol have also been used in the fragrance industry due to its pleasant smell.
References Ren, Q., et al.: J. Food. Agri. Environ., 10, 67 (2012); Mendes, C.E., et al.: Quimica. Nova., 35, 1787 (2012);

Applications a volatile hydroxy acid component of particular body odors
References Rogge, C., et al.: Biochem., 41, 10141 (2002), Natsch, A., et al.: Chem. Biodiversity, 3, 1 (2006), Liu, G., et al.: Biomacromol., 9, 949 (2008),

Applications 3,3-DIPHENYLPROPANOL (cas# 20017-67-8) is a useful research chemical.

Applications 10-Undecen-1-ol (cas# 112-43-6) is a useful research chemical.

Applications 4-Nitro-benzeneethanol is a useful synthetic intermediate. It can be used to synthesize N-phenylethylindole carboxamides as SAR study of allosteric modulators of CB1 receptor. It can also be used to prepare 2-aza-2'-deoxyinosine-containing oligodeoxyribonucleotide duplexes.
References Piscitelli, F., et al.: J. Med. Chem., 55, 5627 (2012); Acedo, M., et al.: J. Org. Chem., 60, 6262 (1995)

Stability Hygroscopic
Applications 2-(2,5-diaminophenyl)ethanol Sulfate (cas# 93841-25-9) is a useful research chemical.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 1,4-Cyclohexanedimethanol diglycidyl ether (cas# 14228-73-0) is a useful research chemical.

Applications Cyclopropylmethanol used to increase selectivity of pyridyl-cinnoline phosphodiesterase 10A, inhibitors against phosphodiesterase 3 (PDE3). Also used in the synthesis of benzodiazapin-2-ones
References Hu, E. et al.: Bioorg. Med. Chem. Lett., 22, 6938 (2012);

Applications Tetrahydro-2H-pyran-2-ol (cas# 694-54-2) is a useful research chemical.

Applications 2-(Benzyloxy)phenol is used in the synthesis of 2-(benzyloxy)hydroquinone by cytochrome P 450 BM-3 mutant F87V as the catalyst.
References Sulistyaningdyah, W.T., et. al.: Appl. Microbiol. Biot., 67, 556 (2005)

Applications 2-(6-Aminopurin-9-yl)ethanol is a useful intermediate in the preparation of aryloxyalkyl derivatives of adenine with antiviral activity.
References Petrov, V. I., et al.: Chemistry of Heterocyclic Compounds, 39, 1218 (2003)

Applications 2H-1,3-benzodithiole-2-thione (cas# 934-36-1) is a useful research chemical.

Applications 2-Ethyl-1,3-hexanediol

Applications (±)-2-Phenylbutanol is used as a reagent in the synthesis of carbamate derivatives of Felbamate (F231000), as potential anticonvulsant agents. (±)-2-Phenylbutanol is also used to prepare analogs of O-(2-phenylethyl)-N-phenylthiocarbamate which can serve as non-nucleoside HIV-1 reverse transcriptase inhibitors.
References Kung, C., et al.: Med. Chem. Res., 19, 498 (2010); Cesarini, S., et al.: Bioorg. Med. Chem., 16, 4173 (2008)

Applications [4-(Trimethylammonium)benzyl] Alcohol Bromide is a compound useful in organic synthesis.

Applications Cyclopentaneethanol is used in the prepartion of phenylalanine derivatives for incorporation into peptides as CD4 mimetic miniproteins interacting with HIV-1 surface glycoprotein. It is also used in the preparation of tertiary amine muscarinic receptor antagonists applied towards the treatment of chronic obstructive pulmonary disease.
References Morellato-Castillo, L. et al.: J. Med. Chem., 56, 5033 (2013); Glossop, P. et al.: J. Med. Chem., 54, 6888 (2011);

Applications 4-(1,3-thiazol-4-yl)phenol (cas# 68535-57-9) is a useful research chemical.

Applications 4,4-Dimethoxybutan-1-ol is a reactant used in the preparation of tetrahydropyranols and hydropyranooxepans.
References Hoffmann, R.W., et. al.: New J. Chem., 25, 102 (2001)

Applications 4-Phenoxyphenol is a porous organic material with dumbbell channels that appear throughout its structure. These channels can also host solvent molecules during crystal growth. 4-Phenoxyphenol is also part of a group of phenolic compounds that have potential apoptotic activity, which can be used in the development of new treatments for cancer therapy.
References Hansch, C., et al.: Bioorg. Med. Chem., 11, 617 (2003); Thomas, L., et al.: Cryst. Growth. Des., 12, 1746 (2012)

Applications M-PEG4-THIOL (cas# 52190-55-3) is a useful research chemical.

Applications Leuco-2,6-dichlorophenolindophenol is the reduced form of DCIP and has been used to measure photocatalytic oxidation.
References Krysa, J.; et al.: Catalysis Today, 240, 132 (2015). Kafizas, A.; et al.: Chemistry - A European Journal, 18, 13048 (2012).

Applications 2-Butoxyethanol is a reagent in the synthesis of 4-butoxyethoxy-N-octadecyl-1,8-naphthalimide as a new fluorescent probe for the determination of proteins. Also used as a reagent in the synthesis of 4-hydroxybenzaldehyde derivatives as tyrosinase inhibitors.
References Sun, Y., et al.: Bioorg. Med. Chem. Lett., 21, 3798 (2011); Yi, W., et al.: Eur. J. Med. Chem., 45, 639 (2010)

Stability Acid Sensitive
Applications 2-tert-Butyldimethylsilyloxyethanol (cas# 102229-10-7) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 5-Propylbenzene-1,3-diol is an intermediate used to prepare Cannabigerovarin (C175140) which stimulates thermosensitive transient receptor potential (TRP) channels of vanilloid type-4 (TRPV4)-mediated [Ca2+]i with moderate-high efficacy (30-60% of the effect of ionomycin) and potency (EC50 0.9-6.4 μM),
References De Petrocellis, L., et al.: Acta Physiologica, 204, 255 (2012)

Applications (3S,4R)-4-aminooxolan-3-ol (cas# 153610-14-1) is a useful research chemical.

Applications 4,4-dimethylpentan-2-ol (cas# 6144-93-0) is a useful research chemical.

Applications 5-Thiazolemethanol (cas# 38585-74-9) is a compound useful in organic synthesis.