Cetonas

Applications Methyl 2-Cyclopentanonecarboxylate is used in the synthesis of functionalized ketones.
References Mashima, K. et al.: J. Org. Chem., 59, 3064 (1994); Hamashima, Y. et al.: J. Am. Chem. Soc., 124, 11240 (2002);

Applications 2-Isobutyrylcyclohexanone (cas# 39207-65-3) is a useful research chemical.

Applications 1,8-Dioxacyclotetradecane-2,9-dione, can be used in synthetic preparation of lipase-catalyzed ring-opening polymerization of molecularly pure cyclic oligomers for use in synthesis and chemical recycling of aliphatic polyesters.
References Kondo, A., et al.: Macromolecular Bioscience, Vol. 8, Iss. 6, P: 533-539 (2008):

Applications 2-Hydroxyimino-3-pentanone is an intermediate in the preparation of indole derivatives.
References Goya, P., et al.: J. Med. Chem., 35, 3977 (1992), Masaguer, C., et al.: Chem. Pharm. Bull., 47, 621 (1999), Wu, S., et al.: Bioorg. Med. Chem. Lett., 16, 5859 (2006),

Applications 4-Hydroxyphenylacetone (cas# 770-39-8) is a useful research chemical.

Applications 3,​3-​Dimethyl-​2,​4-​pentanedione is used in asymmetric hydrosilation of ketones.
References Kuwano, R., et al.: Bull. Chem. Soc. Jpn., 73, 485 (2000).

Applications Cyclopropyl Methyl Ketone is a chemical reagents used in the synthesis of PDE4 inhibitors. Also used in the synthesis of α-trifluoromethyl-amines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ferrer, M. et al.: Tetrahedron Lett., 54, 4821 (2013); Radchenko, D. et al.: Tetrahedron Lett., 54, 1897 (2013);

Applications 4'-Hydroxyflavanone (cas# 6515-37-3) could be a useful antitumor agent, specifically studied as a strong aromatase inhibitor against estrogen-dependent breast cancer.
References Kizilcan, D. S., et al.: Struct. Chem., 31, 1339 (2020)

Applications 1-(2-AMINO-5-HYDROXYPHENYL)ETHANONE (cas# 30954-71-3) is a useful research chemical.

Applications 2-Cyclopentylcyclopentanone (cas# 4884-24-6) is a useful research chemical.

Applications Cyclohexyl phenyl ketone is a useful research chemical in organic synthesis.
References Yang, Tonghao, et al.: Org. Let., 20(7), 1875-1879 (2018);Jarava-Barrera, Carlos, et al.: Chem. - A Euro. J., 23(69), 17478-17481 (2017)

Applications (Z)-1-(Benzo[b]​thiophen-​2-​yl)ethanone Oxime is an isomer of N-​(1-​Benzo[b]​thiophen-​2-​yl-​ethyl)​-​hydroxylamine a reagent used in the preparation of Zileuton, an anti-asthmatic drug.
References Guinchard, X. et al.: J. Org. Chem., 73, 2028 (2008)

Applications 2-NONADECANONE (cas# 629-66-3) is a useful research chemical.

Applications 4,4-Dimethoxy-2-butanone is a reactant in the synthesis of naphthalimide-naphthyridine derivatives as a fluorescent probe for the detection of hydroxyl radicals in living cells.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Meng, L., et. al.: Chem. Commun., 50, 4843 (2014)

Applications 5-(Trifluoromethyl)-1-indanone (cas# 150969-56-5) is a useful research chemical.

Applications 1-(2,4-Bis(benzyloxy)phenyl)ethanone is a useful research chemical for organic synthesis and other chemical processes.
References Chen, D., et al.: Eur. J. Med. Chem., 87, 765 (2014); Malik, N., et al.: Tetrahedron Lett., 54, 4121 (2013)

Applications 1,3-Cyclopentanedione was used in the synthesis of chemical probes for selective labeling of sulfenic acid proteins. It was also used to synthesize enaminones with possible anticonvulsant activity.
References Qian, J., et al.: Chem. Comm., 47, 9203 (2011); Scott, K., et al.: J. Med. Chem., 36, 1947 (1993)

Applications 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE (cas# 2892-51-5) is a useful research chemical.

Applications 4-Phenylcyclohexanone is used in the synthesis of CCR2 antagonists for the treatment of rheumatoid arthritis, atherosclerosis and other disease states. Also used in the preparation of coumarins via dehydrogenation and Heck coupling reactions.
References Subasinghe, N. et al.: Bioorg. Med. Chem. Lett., 23, 1063 (2013); Kim, D. et al.: Chem. Comm., 49, 4021 (2013);

Applications 1,3-Diphenylacetone (cas# 102-04-5) is a useful research chemical.

Applications (5Z,9Z,13Z)-Geranylgeranylacetone is the structural analogue of Teprenone (T103500), an anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.
References Murakami, M., et al.: Arzneim.-Forsch., 31, 799 (1981); Nishizawa, Y., et al.: Xenobiotica, 17, 575 (1987)

Applications (E)-1-(Benzo[b]​thiophen-​2-​yl)ethanone Oxime is an isomer of N-​(1-​Benzo[b]​thiophen-​2-​yl-​ethyl)​-​hydroxylamine a reagent used in the preparation of Zileuton, an anti-asthmatic drug.
References Guinchard, X. et al.: J. Org. Chem., 73, 2028 (2008)

Applications 5-Acetoxy-3-chloro-2-pentanone (cas# 13051-49-5) is a compound useful in organic synthesis.

Applications 1,4-Dihydroxy-2-butanone (cas# 140-86-3) is a useful research chemical.

Stability Moisture Sensitive
Applications 1-(2-oxopropyl)-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione (cas# 57384-79-9) is a useful research chemical.

Applications (2R,​3S,​4S,​5S)-5-Hydroxy-2,3,4-tris(phenylmethoxy)-5-[(phenylmethoxy)methyl]-cyclohexanone was used in the synthetic preparation of N-substituted valiolamine derivatives.
References Fukase, H., et al.: J. Org. Chem., 57, 3642 (1992);

Applications 1-[3,4-Bis(phenylmethoxy)phenyl]ethanone is an intermediate in synthesizing Arbutamine (A766300). It is a cardiac stimulant. Arbutamine stimulates adrenergic receptors.
References Sinusas, A., et al.: J. Nucl. Med., 35, 664 (1994); Sansoy, V., et al.: Circulation, 92, 994 (1995); Elhendy, A., et al.: Eur. J. Nucl. Med., 23, 1354 (1996);

Applications Benzyl p-Toluylketone (cas# 2001-28-7) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Wu, Z., et al.: Bioorg. Med. Chem. Lett., 18, 2211 (2008), Gadad, A., et al.: Bioorg. Med. Chem., 16, 276 (2008),

Applications 4-Cyanocyclohexanone is used to prepare nicotinamides as PDE4 D isoenzymes inhibitors. It is also used as an anthranilic acid replacement in niacin receptor agonist.
References Marfat, A., et al.: PCT Int. Appl. (1998), WO 9845268 A1 19981015; Schmidt, D., et al.: Bioorg. Med. Chem. lett., 20, 3426 (2010)

Applications 1-[2-Hydroxy-5-(2-hydroxyethyl)phenyl]-ethanone (cas# 58282-51-2) is a compound useful in organic synthesis.

Applications 4,4-Dimethyl-1,3-cyclohexanedione (cas# 562-46-9) is a useful research chemical.

Applications 1,3-Indandione is one of the starting materials in the one-pot multi-component synthesis of indenone-fused heterocyclic derivatives. Also it acts as electron-withdrawing end group used for organic photovoltaic cell application.
References Bayayt, M., et al.: Tetrahedron, 73, 1196-1204 (2017); Lim, E.: Mol. Cryst. Liq. Cryst., 635, 94-101 (2016);

Stability Moisture Sensitive
Applications (3R,4R)-Dihydro-3,4-bis(phenylmethoxy)-2,5-furandione is an intermediate in the synthesis of N-alkenylsuccinimide derivatives.
References Ohwada, J., et al.: Bull. Chem. Soc. Jap., 63, 287 (1990);

Applications Cyclopentanone-2-carbonitrile (cas# 2941-29-9) is a useful research chemical. It acts as a reagent in the preparation of quinolines
References Larsen, R. D., et al.: Science of Synthesis, 15, 389 (2005)

Stability Moisture Sensitive
Applications 4,7-dimethyl-1,3-dihydro-2-benzofuran-1,3-dione (cas# 5463-50-3) is a useful research chemical.

Applications 3-(prop-2-yn-1-yl)thiazolidine-2,4-dione (cas# 39137-29-6) is a useful research chemical.

Applications 2,4-DIMETHYL-3-HEPTANONE (cas# 18641-71-9) is a useful research chemical.

Applications 4-(Morpholin-4-yl)cyclohexanone is a useful synthetic intermediate. It was used to synthesize diastereomeric 3,6-diaminobicyclo[3.1.0]hexane derivatives.
References Vilsmaier, E., et al.: Synthesis, 12, 1142 (1991)

Applications 2-Hexanone is used in various organic chemical syntheses. It is used in the synthesis of (+/-)-monomorine. It is also used in the preparation of alcohols by transfer hydrogenation of ketones.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Le, T. et al.: Tetrahedron Lett., 53, 5660 (2012); Ikhile, M. et al.: Tetrahedron Lett., 53, 4925 (2012);

Applications 6,6-Dimethyl-5,7-dioxaspiro[2.5]octan-4,8-dione is used as a reagent to synthesize Bis-benzimidazoles, compounds that act as inhibitors of Type II Dihydrofolate reductase (an enzyme that is produced by bacteria in response to Trimethoprim [T795615]as a defense mechanism).
References Bastien, D., et al.: J. Med. Chem., 55, 3182 (2012)

Applications Dimethyl-1,3-acetonedicarboxylate is used in the preparation of optically active lycorane. It has also been substituted into bispidone derivatives for their use as ligands in PET imaging.
References Yoshizaki, H. et al.: J. Org. Chem., 60, 2016 (1995); Legdali, T. et al.: J. Org. Chem., 77, 11167 (2012);

Applications 3-Isochromanone can be used to prepare an organic catalyst.
References Wu, G., et.al.: Faming Zhuanli Shenqing, 31, (2021);

Applications (E)-2-Heptylidenecyclopentanone, is a common substance that is found in fragrances.

Applications 5-[1-Hydroxy-2-(2,4,5-trifluorophenyl)ethylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione is an impurity of the DPP-IV inhibitor Sitagliptin (S491000).
References Ye, F. et al.: Hech. Huax., 18, 767 (2010); Ahn, J.H, et al.: Bioorg. Med. Chem. Lett., 17, 2622 (2007);

Applications 1,1'-(1,4-phenylene)bis-Ethanone can undergo oxidative C-C Bond Cleavage to synthesize an aryl carboxylic acid with an iodine catalyst . 1,1'-(1,4-phenylene)bis-Ethanone is also capable of Suzuki-Miyaura coupling.
References Xu, L.; et al.: Synlett, 29, 1505 (2018). Xia, Y.; et al.: J. Am. Chem. Soc., 140, 5347 (2018).

Applications 1-[2-Hydroxy-4,6-bis(ethoxymethoxy)phenyl]ethanone (cas# 128837-25-2) is a compound useful in organic synthesis.

Applications 1,1'-[1]Benzothieno[3,2-b][1]benzothiophene-2,7-diylbis[1-octanone] is the intermediate in the synthesis of C8-BTBT (C015010), which is a soluble organic semicoductor used in solution-processed organic field-effect transistors.
References Ebata, H., et al.: J. Am. Chem. Soc., 129, 15732 (2007); Izawa, T., et al.: Adv. Mat., 20, 3388 (2008)

Stability Volatile
Applications Cyclobutanone is a member of cycloketone compounds that have potential genotoxic and cytotoxic effects and are most commonly found in irradiated food.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anandon, A., et al.: EFSA Journal, 9, 1930 (2011); Delincee, H., et al.: Radiat. Phys. Chem., 63, 431 (2002); Obana, H. ,et al.: J. Health Sci., 52, 375 (2006)

Applications 9-HEPTADECANONE (cas# 540-08-9) is a useful research chemical.

Applications 5,6-Dihydroimidazo[4,5,1-jk][1]benzazepine-2,7(1H,4H)-dione (cas# 92260-81-6) is a compound useful in organic synthesis.

Applications 1-Cyclohexylethanone is used in the synthesis of thiosemicarbazide derivatives which exhibits biological activity.
References Venkatesh, K., et al.: J. Chem. Pharm. Res., 7, 437-445 (2015)

Stability Light Sensitive, Temperature Sensitive
Applications Acetoxymethyl Vinyl Ketone (cas# 38982-28-4) is a compound useful in organic synthesis.
References Zingel, V., et al.: Eur. J. Med. Chem., 25, 673 (1990), Sabourin, P., et al.: Carcinogenesis, 13, 1633 (1992),

Applications 1-(2-Hydroxy-4,6-dimethylphenyl)-ethanone was investigated for its properties as an antibacterial agent and urease inhibitory effects.
References Ngan, L.T., et al.: J. Agri. Chem., 60, 9062 (2012); Chermenskaya, T.D., et al.: Industrial. Crops. Prod., 36, 122 (2012);

Applications 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is a fragrant compound that is a key indicator of maple syrup urine disease, a disorder affecting newborn children that is the result of its inability to properly metabolize Valine (V094205), Leucine (L330110) and Isoleucine (I820175). 4,5-Dimethyl-3-hydroxy-2(5H)-furanone is naturally found in fenugreek seeds, and is an odourant present in sherry wines.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Blank, I., et al.: Prog. Flav. Prec. Stud., No vol. given, 103 (1993); Guerra, P. & Yaylayan, V.: J. Agr. Food Chem., 59, 4699 (2011); Mackenzie, D. & Woolf, L.: Brit. Med. J., 1, 90 (1959); Podebrad, F., et al.: J. Inh. Metab. Dis., 22, 107 (1999)

Applications 1,2-Cycloheptanedione is a reagent in the synthesis of 3,3’-Polymethylene-2,2’-bibenzo[b]-1,10-phenanthrolines.
References Rahman, A. F. M., et al.: Heterocycles, 75, 871-877 (2008)

Applications PBD-5,11-dione (cas# 18877-34-4) is a useful research chemical.

Applications (2E)-2-Hexylidenecyclopentanone, is a compound that is found in fragrance.
References Scognamiglio, J., et al.: Food Chem. Tox., 3, S577 (2012)

Applications 2,5-dimethoxycyclohexa-2,5-diene-1,4-dione (cas# 3117-03-1) is a useful research chemical.

Applications 2,2-Diethoxycycloheptanone is an intermediate in the synthesis of 1,2-Cycloheptanedione (C987255), a reagent in the synthesis of 3,3’-Polymethylene-2,2’-bibenzo[b]-1,10-phenanthrolines.
References Rahman, A. F. M., et al.: Heterocycles, 75, 871-877 (2008)

Applications 2-Acetylcyclohexanone is used in the synthesis of 1-(pyridyl)ethanol derivatives that can reduce keto-esters and ketones. Also used in the synthesis of phenothiazine derivatives that can inhibit protein farnesyltransferase molecules and some that show anti-proliferative activity.
References Baciu-Atudosie, L. et al.: Bioorg. Med. Chem. Lett., 22, 6896 (2012); Kawano, S. et al.: Biosci. Biotech. Biochem., 75, 1055 (2011);

Applications 1-(1,3-Benzodioxol-5-yl)-1-hexanone is an intermediate used in the synthesis of 1-(1,3-benzodioxol-5-yl)-2-(1-pyrrolidinyl)-1-Hexanone (B207110), which is also known as MDPHP, is a synthetic cathinone.
References Fowble, K. L.; et al.: Talanta, 179, 546 (2018).

Applications 1-(2,5-Dihydroxyphenyl)ethanone is an intermediate used in various synthetic preparations of pharmaceutical goods, 1-(2,5-Dihydroxyphenyl)ethanone was untilized in the synthesis of new flavonoid fatty acid esters with anti-adipogenic and glucose consumption enhancing activities.
References Zhao, W., et al.: Bioorg. Med. Chem., 19, 3192 (2011); Jayashree, B.S., et al.: Asian. J. Chem., 22, 1055 (2010); Benites, J., et al.: Bioorg. Med. Chem., 16, 862 (2008);

Applications Phenoxy-2-propanone is a general chemical reagent used in the preparation of α-arylthio ketones via DL-proline.
References Vaquer, A. et al.: RSC Adv. 5, 96695 (2015);

Applications 3-Phenylcyclohexanone (cas# 20795-53-3) is a useful research chemical.

Applications Cyclohexyl Vinyl Ketone is a reagent used in the synthesis of α,β-unsaturated carbonyl compounds which are aminotrifluoromethylathiolated.
References Xiao, Q. et al.: Org. LEtt., 17, 6090 (2015) ;

Applications 1-Cyclopropyl-1,3-butanedione is a reagent in regioselective synthesis of pyrazolylpyrazolopyrimidine derivatives in aqueous medium for antimicrobial agents.
References Novinson, T., et al.: J. Med. Chem., 17, 645 (1974); Aggarwal, R., et al.: Eur. J. Med. Chem., 46, 3038 (2011)

Applications 3-Hydroxy-cyclohexanone is a chemical reagent used in organic synthesis. Used in enantioselective conjugate-addition reactions as well as the cross coupling of enantioenriched secondary potassium β-trifluoroboratoamides.
References Molander, G. et al.: Adv. Synth. Catal., 355, 3037 (2013); Kitanosono, T. et al.: Chem. Asian J., 9, 179 (2014);