Ácidos Benzóicos

Octyl gallate is a naturally occurring compound that belongs to the class of gallates. It is a non-toxic, water-soluble antioxidant that has been used as a preservative in foods and pharmaceuticals. Octyl gallate has been shown to inhibit nuclear DNA synthesis by binding to the dinucleotide phosphate (NDP) site on ribonucleotide reductase, thereby preventing the formation of deoxyribonucleotide triphosphates. A rate constant for this reaction has been determined using analytical methods. This compound also inhibits the growth of wild-type strains of Escherichia coli and Staphylococcus aureus, as well as some strains resistant to antibiotics such as erythromycin, chloramphenicol, tetracycline, and clindamycin. Octyl gallate may also have an effect on energy metabolism in bacteria by inhibiting p-hydroxybenzoic acid (PHBA) dehydratase

2-Hydroxy-6-methylbenzoic acid is a natural product that is synthesized by the enzyme p. pastoris. It is a member of the polyketide class of compounds and has shown to have physiological effects such as anti-inflammatory and antioxidant properties. 2-Hydroxy-6-methylbenzoic acid also has been shown to inhibit ATP binding cassette transporter (ABC) proteins, which are involved in drug resistance, from transporting drugs out of cells, making it an attractive candidate for drug discovery.

2-Amino-5-iodobenzoic acid (5-AIBA) is a chemical compound with a molecular weight of 152.14 g/mol. It belongs to the group of anthranilic compounds, and has antiinflammatory activity. 5-AIBA also inhibits cancer cell proliferation in vitro and in vivo by inhibiting the synthesis of DNA, RNA, and proteins. The reaction solution for the palladium-catalyzed coupling of 5-AIBA with 2-(N,N′-dimethylcarbamoyl)phenyl boronic acid was found to be stable at room temperature for 24 hours. The inhibitory activity of 5-AIBA against MCL1 protein was potent, as it inhibited MCL1 protein expression by 90%. Molecular modeling studies showed that 5-AIBA binds to the amide region on the ATP binding site in MCL1 protein (mcf7). Carbonyl groups are present on both sides of the am

3-Hydroxy-2,4,6-triiodobenzoic acid (3HITBA) is a molecule that is found in the urine of patients with chronic kidney disease. It is present in group P2 of the periodic table. 3HITBA has been demonstrated to have anti-inflammatory properties and may be useful for the treatment of inflammatory diseases. 3HITBA has been shown to inhibit cancer cell growth by inhibiting DNA synthesis and protein synthesis. This molecule also has fluorescence properties and can be used to detect biological fluids such as blood or urine. The structural analysis of this molecule reveals that it contains intramolecular hydrogen bonds, which are important for its stability and activity.

3-Methoxy-2,4,5-trifluorobenzoic acid (3MTBF) is a ligand that binds to the active site of bacterial dehydrogenases. It is used to inhibit the growth of bacteria in the environment and food products. 3MTBF inhibits the production of fluoroquinolones by methylating their chlorides with methoxy groups. This compound also has bifunctional properties, as it can act as both a methylating agent and an inhibitor of dehydrogenase enzymes. 3MTBF inhibits the production of cancer cells by inhibiting transcription and translation, preventing cell division and proliferation. 3MTBF is thermostable, meaning it does not break down in high temperatures or at pH extremes.

Flavoring agent; interacts with TPRV receptors and ASIC channels

2-Chloro-4-trifluoromethylbenzoic acid is a chemical compound with the formula CHClFO. It can be obtained by deprotonation of 2,4,6-trichlorobenzoic acid with butyllithium and subsequent reaction with chlorotrifluoromethane. The product has two regioisomers, one in which the chlorine atom is attached to the para position on the benzene ring and the other in which it is attached to the ortho position. Substituents such as alkyl groups or lithium reagents can affect both reactivity and selectivity. The halogen substituent can also be replaced by other functional groups to make derivatives of this compound.