Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.482 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.602 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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Beclomethasone 21-Propionate
CAS:Produto Controlado<p>Impurity Beclomethasone Dipropionate EP Impurity A<br>Applications Beclomethasone 21-Propionate (Beclomethasone Dipropionate EP Impurity A) is a metabolite of Beclomethasone Dipropionate (BDP).<br>References Foe, K., et al.: Biopharm. Drug Disposition, 19, 1 (1998), Harrison, L., et al.: Eur. J. Clin. Pharmacol., 58, 197 (2002),<br></p>Fórmula:C25H33ClO6Cor e Forma:WhitePeso molecular:464.98(5α)-Androst-2-en-17-one, 90%
CAS:Produto Controlado<p>Applications Metabolite of 5α-Androst-16-en-3β-ol<br>References Gower, D., et al.: J. Steroid Biochem. Mol. Biol., 63, 81 (1997), Zorko, M., et al.: Steroids, 65, 46 (2000), Diel, P., et al.: Toxicol. Lett., 169, 64 (2007),<br></p>Fórmula:C19H28OPureza:90%Cor e Forma:NeatPeso molecular:272.426-Methoxy-2-naphthol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 6-Methoxy-2-naphthol is a reactant in the development of sirtuin inhibitors from pyrazolone and isoxazol-5-one cambinol analogs.<br>References Mahajan, S.S., et. al.: J. Med. Chem., 57, 3283 (2014)<br></p>Fórmula:C11H10O2Cor e Forma:NeatPeso molecular:174.20Dipropofol
CAS:<p>Impurity Propofol EP Impurity E; Propofol USP Related Compound A<br>Applications Dipropofol (Propofol EP Impurity E) is a dimeric derivative of Propofol (P829750). Dipropofol is an antibacterial agent with strong activity againts Gram-positive bacteria. Dipropofol also displays antioxidant and radical scavenging activity. Propofol USP Related Compound A.<br>References Ogata, M. et al.: Chem. Pharm. Bull., 53, 344 (2005); Ogata, M. et al.: Biol. Pharmac. Bull., 30, 1565 (2007);<br></p>Fórmula:C24H34O2Cor e Forma:NeatPeso molecular:354.535-Hydroxycytosine
CAS:Produto Controlado<p>Applications 5-Hydroxycytosine, is been identified as an anomalous base of phage H-17 DNA. It is also a monosubstituted cytosine, as nucleotide-base antimetabolite-type potential anticarcinogen.<br>References Khromov, I. S. Doklady Akademii Nauk SSSR, 240, 1486 (1978); Ladik, J., et al.: Magyar Kemiai Folyoirat, 76, 589 (1970);<br></p>Fórmula:C4H5N3O2Cor e Forma:NeatPeso molecular:127.101-Naphthyl Acetate
CAS:Produto Controlado<p>Applications 1-Naphthyl Acetate (cas# 830-81-9) is a useful research chemical.<br></p>Fórmula:C12H10O2Cor e Forma:NeatPeso molecular:186.207E-1-(2-Cyano-2-Hydroxyiminoacetyl)-3-Ethylurea
CAS:<p>Stability Moisture Sensitive<br>Applications E-1-(2-Cyano-2-hydroxyiminoacetyl)-3-ethylurea is an oxime containing compound that can be used as a reactant in the synthesis of Cymoxanil (C988995), which is a fungicide applied as seed treatment or as foliar application to the plants to control late blight.<br>References Greci, L., et al.: J. Chem. Res., Synop., 1, 655 (2003); Dhingani, J. C., et al.: J. Pure. App. Microbiol., 6, 1683 (2012); Bakirici, G.T., et al.: Food. Chem., 135, 1901 (2012);<br></p>Fórmula:C6H8N4O3Cor e Forma:NeatPeso molecular:184.15Inosine-5'-monophosphate Disodium Salt Hydrate
CAS:Produto Controlado<p>Applications Inosine-5'-monophosphate Disodium Salt Hydrate is used in Raman spectra of alkali and alkaline earth metal salts of inosine 5'-monophosphoric acid.<br>References Carmona, P., et al.: J. Raman Spectrosc., 27, 817 (1996)<br></p>Fórmula:C10H11N4O8PNa·xH2OCor e Forma:NeatPeso molecular:392.17+144.12Mycophenolic Acid Phenolic β-D-Glucoside
CAS:Produto ControladoFórmula:C23H30O11Cor e Forma:White To Off-WhitePeso molecular:482.48Homogentisic Acid-13C6
CAS:<p>Applications Labelled Homogentisic acid. An intermediate in the metabolism of tyrosine and phenylalanine. Occurs in plants and in the urine of alkaptonurics.<br>References Knox, W.E., et al.: Biochem. J., 49, 686 (1951), LaDu, B.N., et al.: J. Biol. Chem., 217, 777 (1955)<br></p>Fórmula:C213C6H8O4Cor e Forma:NeatPeso molecular:174.13,5-Dinitropyridine
CAS:Produto Controlado<p>Applications 3,5-Dinitropyridine is used as an azabenzyne pyrolytic precursor. The anion radical of 3,5-dinitropyridine aundergoes reversible dimerization reactions.<br>References Winkler, M., et al.: J. Am. Chem. Soc., 126, 6135 (2004); Macias-Ruvalcaba, N., et al.: J. Electroanal. Chem., 600, 294 (2007)<br></p>Fórmula:C5H3N3O4Cor e Forma:NeatPeso molecular:169.102'-Hydroxybiphenyl-3-carboxylic Acid
CAS:<p>Applications 2'-Hydroxybiphenyl-3-carboxylic acid<br></p>Fórmula:C13H10O3Cor e Forma:NeatPeso molecular:214.22Pipamazine
CAS:<p>Applications Pipamazine is a drug od the phenothiazine class which used to be used as an antiemetic.<br>References Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 22, 154 (1964); Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 21, 436 (1963);<br></p>Fórmula:C21H24ClN3OSCor e Forma:NeatPeso molecular:401.952,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone
CAS:Produto Controlado<p>Impurity Voriconazole EP Impurity A; Voriconazole USP Related Compound C<br>Applications 2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (Voriconazole EP Impurity A; Voriconazole USP Related Compound C) is an antifungal activity, particularly toward Candida albicans and Candida parapsilosis<br>References Upadhayaya, R., et al.: Eur. J. Med. Chem., 39, 579 (2004), Sheng, C., et al.: J. Med. Chem., 49, 2512 (2006),<br></p>Fórmula:C10H7F2N3OCor e Forma:BeigePeso molecular:223.18Diazolidinyl Urea (Technical Grade)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Diazolidinyl urea is an antimicrobial agent.<br></p>Fórmula:C8H14N4O7Cor e Forma:White To Off-WhitePeso molecular:278.22Calcium Chloride Hydrate
CAS:<p>Applications Calcium Chloride Dihydrate is used in the preparation of bisphosphonates used in attacking cancer cells.<br>References Liu, D. et al.: Chem. Comm., 48, 2668 (2012);<br></p>Fórmula:Ca·2Cl·2H2OCor e Forma:NeatPeso molecular:147.014’-Benzyloxy-3’-nitroacetophenone
CAS:Produto Controlado<p>Applications 4’-Benzyloxy-3’-nitroacetophenone (cas# 14347-05-8) is a compound useful in organic synthesis.<br></p>Fórmula:C15H13NO4Cor e Forma:NeatPeso molecular:271.273-Hydroxy-2-naphthoic acid
CAS:Produto Controlado<p>Applications 3-Hydroxy-2-naphthoic acid<br></p>Fórmula:C11H8O3Cor e Forma:NeatPeso molecular:188.18ethyl (4-nitrophenyl)carbamate
CAS:Produto Controlado<p>Applications ethyl (4-nitrophenyl)carbamate (cas# 2621-73-0) is a useful research chemical.<br></p>Fórmula:C9H10N2O4Cor e Forma:NeatPeso molecular:210.18α-Methylene-γ-valerolactone
CAS:Produto Controlado<p>Applications alpha-Methylene-gamma-valerolactone (cas# 62873-16-9) is a useful research chemical.<br></p>Fórmula:C6H8O2Cor e Forma:NeatPeso molecular:112.126Dihydroabietic Acid (Technical Grade)
CAS:Produto Controlado<p>Applications Dihydroabietic Acid is a resin acid reduction product and may be useful in the treatment of inflammation.<br>References Kang, M. et al.: Biochem. Biophys. Res. Comm., 369, 338 (2009);<br></p>Fórmula:C20H32O2Cor e Forma:NeatPeso molecular:304.467Diphenyl-2,2',4,4',6,6'-d6-amine
CAS:Produto Controlado<p>Applications Diphenyl-2,2',4,4',6,6'-d6-amine (CAS# 99234-91-0) is a useful isotopically labeled research compound.<br></p>Fórmula:C12D6H5NCor e Forma:NeatPeso molecular:175.26apo-Ipratropium Bromide (mixture of stereoisomers)
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 8-Isopropyl-8-methyl-3-endo((2-phenylacryloyl)oxy)-8-azabicyclo[3.2.1]octan-8-ium Bromide is an intermediate used in the preparation of quaternary salts of alkaloids.<br>References Ivanov, V., et al.: Farmatsiya17, 18 (1967)<br></p>Fórmula:C20H28NO2·BrCor e Forma:NeatPeso molecular:394.342-Amino-1-naphthalenesulfonic Acid
CAS:Produto Controlado<p>Applications 2-Amino-1-naphthalenesulfonic Acid has been used in the preparation of oligomeric acid azo dyes and yields a reddish orange color in the dye.<br>References Shah, T.B., et. al.: Int. J. Polyemric Mater., 58, 681 (2009); Smith, K., et. al.: J. Environ., Res. Development, 2, 20 (2007)<br></p>Fórmula:C10H9NO3SCor e Forma:NeatPeso molecular:223.252'-Aminoacetophenone
CAS:<p>Applications 2'-Aminoacetophenone, is detected in the breath of Pseudomonas aeruginosa colonized cystic fibrosis patients. It is also present in various food products causing different off-flavors.<br>References Christoph, N. N., et al.: Advances Exp. Med. Bio., 467, 659 (1999); Scott, A. A., et al.: J. Breath Rese., 5(4), 046002 (2011);<br></p>Fórmula:C8H9NOCor e Forma:NeatPeso molecular:135.16γ-Butyrobetaine-d9 Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled analogue of γ-Butyrobetaine, a synthetic carnitine related compound used as a transporter substrate in the cloning and sequencing of human carnitine transporter 2 (CT2).<br>References Enomoto, A. et al.: J. Biol. Chem., 277, 36262 (2002);<br></p>Fórmula:C72H9H7NO2·ClCor e Forma:NeatPeso molecular:190.72trans-Nerolidol
CAS:Produto Controlado<p>Applications Nerolidol (cas# 40716-66-3) is a terpene standard found in cannabis.<br></p>Fórmula:C15H26OCor e Forma:NeatPeso molecular:222.373,7,4'-Trihydroxyflavone
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3,7,4'-Trihydroxyflavone (cas# 2034-65-3) is a useful research chemical.<br></p>Fórmula:C15H10O5Cor e Forma:NeatPeso molecular:270.24O,N-Aminomethanylylidene-β-D-arabinofuranose
CAS:Produto Controlado<p>Applications O,N-Aminomethanylylidene-β-D-arabinofuranose (cas# 27963-98-0) is a compound useful in organic synthesis.<br></p>Fórmula:C6H10N2O4Cor e Forma:NeatPeso molecular:174.15Robinetin
CAS:Produto Controlado<p>Applications Robinetin (cas# 490-31-3) is a useful research chemical.<br></p>Fórmula:C15H10O7Cor e Forma:NeatPeso molecular:302.24Dihydro Caffeic Acid 3-O-Sulfate Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Caffeic Acid. Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>Fórmula:C9H8Na2O7SCor e Forma:NeatPeso molecular:306.20p-Azidoacetophenone
CAS:Produto Controlado<p>Applications p-Azidoacetophenone (cas# 20062-24-2) is a compound useful in organic synthesis.<br>References Zarghi, A., et al.: Bioorg. Med. Chem., 14, 7044 (2006), Cline, M., et al.: Biochem., 46, 1981 (2007),<br></p>Fórmula:C8H7N3OCor e Forma:NeatPeso molecular:161.16Bisphenol A Bissulfate-d6 Disodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A labelled bisphenol derivative having antihemolytic activity.<br>References Morgan, B., et al.: Eur. J. Clin. Invest., 24, 219 (1994), Liszewski, M., et al.: Adv. Immunol., 61, 201 (1996), Assefa, H., et al.: Bioorg. Med. Chem. Lett., 9, 1889 (1999), Burdelev, O., et al.: Bioorg. Khim., 29, 159 (2003),<br></p>Fórmula:C15H8D6Na2O8S2Cor e Forma:NeatPeso molecular:438.41Guanosine 5'-Diphosphate Disodium Salt
CAS:Produto Controlado<p>Applications Guanosine 5'-diphosphate disodium salt (cas# 7415-69-2) is a useful research chemical.<br></p>Fórmula:C10H13N5Na2O11P2Pureza:>85%Cor e Forma:NeatPeso molecular:487.16(2-Chloroethyl) Phosphonic Acid-d4
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled (2-Chloroethyl)phosphonic acid. (2-Chloroethyl)phosphonic acid (Ethephon) is the most widely used plant growth regulator. Ethephon is often used on wheat, coffee, tobacco, cotton, and rice in order to help the plant's fruit reach maturity more quickly. The toxicity of Ethephon is actually very low, and any Ethephon used on the plant is converted very quickly to ethylene.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brantley, B., et al.: J. Plant Physiol., 1428, 741 (1960), Ntui, V., et al.: J. Food Agricult. Environ., 5, 211 (2007), Vwioko, E., et al.: Biosci. Res. Communic., 21, 263 (2009),<br></p>Fórmula:C22H4H2ClO3PCor e Forma:NeatPeso molecular:148.52Caffeic Acid-13C3
CAS:<p>Applications Constituent of plants, probably occurs in plants only in conjugated forms.<br>References Neish, et al.: Can. J. Biochem Physiol., 37, 1431 (1959), Krasemann, et al.: Arch. Pharm., et al.: 293, 721 (1960), Wolfrom, et al.: J. Agric. Food Chem., 8, 58 (1960),<br></p>Fórmula:C613C3H8O4Cor e Forma:NeatPeso molecular:183.144-Hydroxychlorpropham Sulfate Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-Hydroxychlorpropham Sulfate Sodium Salt, is a chemical herbicide used in the protection of crops. It also maintains the ability to induce mitochondrial dysfunction in rat hepatocytes.<br>References EPA.: Fed. Reg., 72, 37646 (2007); Nakagawa, Y. et al.: Toxicol., 200, 123 (2004);<br></p>Fórmula:C10H11ClNNaO6SCor e Forma:NeatPeso molecular:331.705Ginsenoside C-K
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Ginsenoside C-K is reported to exhibit anti-wrinkle effects. Also, it potentiates tumor necrosis factor (TNF)-related apotosis-inducing ligand (TRAIL)-induced apotosis in HCT116 colon cancer.<br>References Han, S., et al.: J. Cell. Biochem., (2017); Chen, L., et al.: Cell Death Diff., 7, 2334 (2016)<br></p>Fórmula:C36H62O8Cor e Forma:NeatPeso molecular:622.87(-)-Citronellal
CAS:Produto Controlado<p>Applications (-)-Citronellal is the s-isomer of (R)-Citronellal (C525025), a natural insect repellant. (-)-Citronellal (a monoterpene) was found to activate human olfactory receptor OR1A2 at the mRNA and protein levels resulting in reduced cell proliferation and reduced hepatocellular carcinoma progression.<br>References Massberg, D., et al.: Arch. Biochem. Biophys., 566, 100 (2015);<br></p>Fórmula:C10H18OCor e Forma:NeatPeso molecular:154.257-Methoxy-1-naphthaleneacetamide
CAS:Produto Controlado<p>Applications 7-Methoxy-1-naphthaleneacetamide, can be used for the synthesis of the analogs of Melatonin (M215000), containing naphthalene moiety instead of indole nucleus, having high affinity for the melatonin receptor. Agomelatine Impurity 6<br>References Tang, J. D., et al.: Org. Prep. Proc. Int., 41, 164 (2009); Sndrieux Y. J., et al.: J. Med. Chem., 35, 1484 (1992);<br></p>Fórmula:C13H13NO2Cor e Forma:NeatPeso molecular:215.25Hematoporphyrin Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Hematoporphyrin dihydrochlordie (cas# 17696-69-4) is a useful research chemical.<br></p>Fórmula:C34H38N4O6·2ClHCor e Forma:NeatPeso molecular:671.61Indole-3-pyruvic Acid-d5
CAS:Produto Controlado<p>Applications Indole-3-pyruvic Acid-d5 is an isotope labelled compound of Indole-3-pyruvic Acid (I627189). Indole-3-pyruvic Acid is a compound involved in the biosynthesis of Indole-3-acetic acid, a plant hormone which plays important roles in regulating growth and responses to environmental changes.<br>References Kong, W., et al.: Plant Cell Physiol, 56, 715-726 (2015)<br></p>Fórmula:C11H4D5NO3Cor e Forma:Light Brown To BrownPeso molecular:208.22(2-Naphthyloxy)acetyl Chloride
CAS:Produto Controlado<p>Applications (2-Naphthyloxy)acetyl Chloride serves as one of the reagents for the discovery of indoline-2-carboxamide derivatives as new classs of brain-penetrant inhibitors of trypanosoma brucei. Also in preparation and antibacterial activity of N-(phenylquinazolinonyl) aryl-amides by amidation of amino(phenyl)quinazolone with aroyl chlorides<br>References Cleghorn, L. A., et al.: J. Med. Chem., 58, 7695 (2015); Prajapati, A. K., et al.: Indian J. Heterocycl. Chem., 19, 269 (2010)<br></p>Fórmula:C12H9ClO2Cor e Forma:NeatPeso molecular:220.652(-)-2-Methyl Isoborneol-d3
CAS:Produto Controlado<p>Applications Isotope labelled (-)-2-Methylisoborneol (M314000), which is a derivative of Camphor (1) (C165805). (-)-2-Methylisoborneol is a flavor component of Robusta coffee responsible for the off-flavour aroma (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Money T. Nat Prod Rep. 1985 Jun;2(3):253-89.2. Blank I et al.: J Agric Food Chem. 2002 Jul 31;50(16):4653-6.<br></p>Fórmula:C112H3H17OCor e Forma:NeatPeso molecular:171.29(±)5,6-DiHETE Lactone
Produto Controlado<p>Stability Moisture Sensitive<br>Applications (±)5,6-DiHETE Lactone is a 1,5 cyclic ester derived from (±)5(6)-DiHETE. A useful research intermediate.<br></p>Fórmula:C20H30O3Cor e Forma:NeatPeso molecular:318.453-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid
CAS:Produto Controlado<p>Applications 3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid (cas# 104582-29-8) is a compound useful in organic synthesis.<br>References Kobayashi, N., et al.: Anal. Biochem., 357, 311 (2006),<br></p>Fórmula:C15H25N3O4S3Cor e Forma:NeatPeso molecular:407.572-Nonenedioic Acid
CAS:Produto Controlado<p>Applications 2-Nonenedioic Acid is an impurity of Azelaic acid (A808140) which is an antiacne agent.<br>References Bladon, P.T., et al.: Br. J. Dermatol., 114, 493 (1986)<br></p>Fórmula:C9H14O4Cor e Forma:White To Light BeigePeso molecular:186.21Tetrachloroauric Acid
CAS:Produto Controlado<p>Applications Tetrachloroauric Acid, is used for the recovery, concentrating, purification, and analytical determinations of gold. It is the precursor used in the purification of gold by electrolysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mironov, I. V., et al.: Russian J. Inorg. Chem., 57, 610 (2012); Feather, A., et al.: J. Southern Africa Inst. mining Metal., 169 (1997);<br></p>Fórmula:AuCl3·ClHCor e Forma:NeatPeso molecular:339.79
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