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Padrões Farmacêuticas

Padrões Farmacêuticas

Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.

Subcategorias de "Padrões Farmacêuticas"

Foram encontrados 7836 produtos de "Padrões Farmacêuticas"

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  • 3-Nitrophthalodinitrile

    CAS:
    <p>3-Nitrophthalodinitrile is a chemical compound that can be used to treat wastewater. It has been shown to have photophysical properties, fluorescence properties, and structural formula. 3-Nitrophthalodinitrile has been shown to be a good fluorescent probe for the detection of multi-walled carbon nanotubes in the environment. 3-Nitrophthalodinitrile has also been found to have fluorescence lifetimes and nmr spectra that are different depending on whether it is in its ground state or excited state. 3-Nitrophthalodinitrile has been shown to react with nucleophiles such as water, alcohols, and amines. Furthermore, it has been found to be able to undergo transfer reactions with other chemical species such as formaldehyde and nitrite ions. 3-Nitrophthalodinitrile is capable of undergoing dehydration without any side products being formed. This makes it an excellent candidate for use in optical applications</p>
    Fórmula:C8H3N3O2
    Pureza:Min. 95%
    Cor e Forma:Slightly Yellow Powder
    Peso molecular:173.13 g/mol

    Ref: 3D-FN00922

    1kg
    310,00€
    2kg
    471,00€
    500g
    192,00€
  • 3-(Trifluoromethoxy)hydrocinnamic acid

    CAS:
    <p>3-(Trifluoromethoxy)hydrocinnamic acid is a useful building block that is used in the synthesis of many organic compounds. It has been used as a reagent and as a speciality chemical, and is also a versatile building block for the synthesis of complex compounds. 3-(Trifluoromethoxy)hydrocinnamic acid can be synthesized from cinnamic acid, which is available commercially and can be obtained by reacting benzaldehyde with nitric acid. 3-(Trifluoromethoxy)hydrocinnamic acid has CAS No. 168833-77-0 and can be found under the name 2,4-dichloro-3-(trifluoromethoxy)benzene.</p>
    Fórmula:C10H9F3O3
    Pureza:Min. 98 Area-%
    Cor e Forma:Clear Liquid
    Peso molecular:234.17 g/mol

    Ref: 3D-FT67019

    10g
    135,00€
    25g
    181,00€
  • 4-Methylsalicylic acid

    CAS:
    <p>4-Methylsalicylic acid is a chemical compound that belongs to the group of salicylates. It is an organic compound with a molecular weight of 96.12 g/mol and the chemical formula C8H8O3. The epoxidation of 4-methylsalicylic acid occurs through the use of catalysts, such as zinc oxide and manganese dioxide, which are not functionalized. The addition of these catalysts causes a reaction between the methyl group and the hydroxyl group in 4-methylsalicylic acid, forming methyl salicylate. This product is also used as a chiral building block for other compounds, such as axial chirality and olefins.</p>
    Fórmula:C8H8O3
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:152.15 g/mol

    Ref: 3D-FM25564

    1kg
    330,00€
    100g
    140,00€
    250g
    153,00€
    500g
    208,00€
  • 3,5,3',5'-Tetraiodothyroacetic acid

    CAS:
    <p>3,5,3',5'-Tetraiodothyroacetic acid (T4) is a thyroid hormone that can be found in the blood and has been shown to have angiogenic properties. T4 has been shown to bind to integrin receptors on endothelial cells and stimulate the proliferation of these cells. This hormone also has pro-apoptotic activity, inducing programmed cell death in cancer cells. T4 is used as a model system for studying the molecular pathogenesis of thyroid cancer. T4 is also able to inhibit DNA polymerase activity, which may be responsible for its ability to inhibit tumor growth.</p>
    Fórmula:C14H8I4O4
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:747.83 g/mol

    Ref: 3D-FT28150

    1g
    1.074,00€
    2g
    1.627,00€
    100mg
    254,00€
    250mg
    454,00€
    500mg
    728,00€
  • 1-Acenaphthenone

    CAS:
    <p>1-Acenaphthenone is a heterocyclic compound that contains a hydroxyl group, chlorine atom, and two rings. It is used as a catalyst in organic synthesis. 1-Acenaphthenone has been shown to be an efficient dioxygenation catalyst for the production of 1-hydroxy-2-naphthoic acid from malonic acid. It also has been used as a solid catalyst in the oxidation of fatty acids with hydrogen peroxide and as an enzyme activator for rat liver microsomes. This compound also shows synchronous fluorescence with other compounds such as 1-hydroxy-2-naphthoic acid and 2-(2'-oxobiphenyl)acetic acid.</p>
    Fórmula:C12H8O
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:168.19 g/mol

    Ref: 3D-FA15900

    1g
    135,00€
    2g
    135,00€
    5g
    185,00€
    10g
    277,00€
  • Ibuprofen

    CAS:
    <p>Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used for the treatment of pain, fever and inflammation. Ibuprofen is an inhibitor of cyclooxygenase 1 (COX-1), which blocks the production of prostaglandins that cause pain and inflammation. Ibuprofen has been shown to inhibit the growth of bacteria in cell culture by inhibiting protein synthesis. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis. Ibuprofen has been shown to inhibit the production of tumour necrosis factor-α (TNF-α) and serum enzymes, such as dismutase activity, in mice with lung cancer.</p>
    Fórmula:C13H18O2
    Pureza:Min. 98 Area-%
    Cor e Forma:White Powder
    Peso molecular:206.28 g/mol

    Ref: 3D-FI15848

    1kg
    382,00€
    2kg
    509,00€
    5kg
    978,00€
    10kg
    1.356,00€
    500g
    305,00€
  • 4'-Hydroxychalcone

    CAS:
    <p>4'-Hydroxychalcone is a compound that has shown to be an insulin resistance suppressant. It reduces the activity of recombinant cytochrome P450 enzymes and blocks hydroxy group metabolism, which leads to a decrease in ATP levels. This molecule also has biological properties as it can inhibit the expression of β-catenin and induce apoptosis in cancer cells. 4'-Hydroxychalcone has been found to inhibit the transfer mechanism of phosphatidylinositol 3-kinase (PTP1B) and is able to bind with the protein marker p62/SQSTM1. <br>4'-Hydroxychalcone is a potent inhibitor for PTP1B, which is a negative regulator for insulin signaling pathways. In addition, 4'-hydroxychalcone can bind with p62/SQSTM1, which is a marker for autophagy proteins. These properties have been shown to have anti-cancer effects on multiple cancer types including</p>
    Fórmula:C15H12O2
    Cor e Forma:Powder
    Peso molecular:224.25 g/mol

    Ref: 3D-FH36595

    25g
    135,00€
    50g
    190,00€
    100g
    265,00€
  • 4,4' -Bis(N,N-dimethylamino)-2,2' -bipyridine

    CAS:
    <p>4,4' -Bis(N,N-dimethylamino)-2,2' -bipyridine (DMAB) is a ligand that is used in electrochemical studies. It has been shown to have ancillary properties, which means that it does not interact directly with the substrate but modifies its environment. DMAB can form a complex with the proton at the electrode surface and x-ray crystal structures have been obtained for this interaction. These structures demonstrate that DMAB binds to the tetrazole ring of pyridine and stabilizes the molecule by increasing its redox potentials.</p>
    Fórmula:C14H18N4
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:242.32 g/mol

    Ref: 3D-FB161440

    1g
    607,00€
    250mg
    291,00€
    500mg
    410,00€
  • Fmoc-O-benzylphospho-L-tyrosine

    CAS:
    <p>Fmoc-O-benzylphospho-L-tyrosine is a synthetic amino acid that can be used as a molecular model for tyrosine kinases. Fmoc-O-benzylphospho-L-tyrosine has been shown to inhibit the activity of tyrosine phosphatases. It also binds to phosphate groups in the presence of calcium ions, which may help to immobilize it and prevent its hydrolysis by phosphatases. The binding constants of Fmoc-O-benzylphospho-L-tyrosine with these phosphate groups are determined using analytical chemistry. Fmoc-O-benzylphospho-L-tyrosine has been found to bind to immobilized cells and be expressed at high levels in mammalian cells.</p>
    Fórmula:C31H28NO8P
    Pureza:Min. 97 Area-%
    Cor e Forma:White Powder
    Peso molecular:573.53 g/mol

    Ref: 3D-FF47780

    1g
    269,00€
    2g
    425,00€
    5g
    599,00€
    10g
    1.049,00€
    25g
    2.146,00€
  • 3-Hydroxy-7,2',4',5'-tetramethoxychalcone


    <p>3-Hydroxy-7,2',4',5'-tetramethoxychalcone is a versatile building block that can be used as a reagent or in the synthesis of fine chemicals. It is an intermediate or reaction component that has been found to be useful in the synthesis of complex compounds. This compound is also of high quality and can be used as a scaffold in the synthesis of new molecules. 3-Hydroxy-7,2',4',5'-tetramethoxychalcone is a speciality chemical, with CAS No. 55006-57-3 and molecular weight of 245.</p>
    Pureza:Min. 95%

    Ref: 3D-FH67446

    5g
    135,00€
    10g
    149,00€
    25g
    254,00€
  • Monomethyl auristatin E

    CAS:
    <p>Synthetic analog of dolastatin 10; cytotoxic; inhibits tubulin polymerization</p>
    Fórmula:C39H67N5O7
    Pureza:Min. 98 Area-%
    Cor e Forma:White Off-White Powder
    Peso molecular:717.98 g/mol

    Ref: 3D-FM63498

    10mg
    135,00€
    25mg
    193,00€
    50mg
    300,00€
    100mg
    456,00€
  • 3,3',5-Triiodo thyroacetic acid

    CAS:
    <p>3,3',5-Triiodo thyroacetic acid is a synthetic thyroid hormone that acts as a thyroid hormone receptor agonist. It binds to the thyroid hormone receptor, leading to the activation of other transcription factors and increased synthesis of proteins. 3,3',5-Triiodo thyroacetic acid has been shown to increase the metabolic rate in rats by increasing the expression of epidermal growth factor in skin cells and signal transduction in nerve cells. This drug also causes an increase in transcriptional regulation and protein synthesis. 3,3',5-Triiodo thyroacetic acid does not have any known side effects or toxicity.</p>
    Fórmula:C14H9I3O4
    Pureza:Min. 95%
    Cor e Forma:White Off-White Powder
    Peso molecular:621.93 g/mol

    Ref: 3D-FT28502

    1g
    495,00€
    2g
    735,00€
    5g
    1.050,00€
    250mg
    220,00€
    500mg
    352,00€
  • 4-N-Butoxycinnamic acid

    CAS:
    <p>4-N-Butoxycinnamic acid is a chemical compound with the molecular formula CH3(CH2)7COCH=CH(COOH). It belongs to the group of cinnamic acid derivatives, which are organic compounds that may be synthesized by condensation of malonic acid and benzene. 4-N-Butoxycinnamic acid has been shown to have anti-inflammatory properties in animal models. This compound inhibits inflammatory cytokines and their signaling pathways, thereby preventing the translocation of neutrophils into inflamed tissues.</p>
    Fórmula:C13H16O3
    Pureza:Min. 95%
    Peso molecular:220.26 g/mol

    Ref: 3D-FB67351

    25g
    135,00€
  • Hydrocinnamic acid

    CAS:
    <p>Hydrocinnamic acid is an inhibitor of the enzyme carboxyl ester lipase. It is used to treat inflammatory bowel disease and autoimmune diseases, such as Crohn's disease. Hydrocinnamic acid has also been shown to inhibit the production of inflammatory mediators, such as prostaglandins, leukotrienes, and cytokines. This anti-inflammatory effect may be related to its ability to inhibit the activity of lipoxygenases and cyclooxygenases. Hydrocinnamic acid has also been shown to act as a broad-spectrum antimicrobial agent against bacteria, fungi, and viruses.</p>
    Fórmula:C9H10O2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:150.17 g/mol

    Ref: 3D-FH23881

    500g
    135,00€
  • 1-(2,5-Dibromophenyl)ethanone

    CAS:
    <p>2',5'-Dibromoacetophenone is an imine that has been shown to be a potent inhibitor of NS5A. It is used in the synthesis of elbasvir and other pharmaceuticals. The enantioselective synthesis of 2',5'-dibromoacetophenone is achieved by using a chiral catalyst derived from camphor, which can produce the desired product in large quantities with high purity.</p>
    Fórmula:C8H6Br2O
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:277.94 g/mol

    Ref: 3D-FD70431

    1g
    343,00€
    2g
    454,00€
    500mg
    208,00€
  • Dimethyl 4-nitrophthalate

    CAS:
    <p>Dimethyl 4-nitrophthalate is a bioactive molecule that has been found to be effective in inhibiting the growth of bacteria, including methicillin-resistant Staphylococcus aureus and Mycobacterium tuberculosis. Dimethyl 4-nitrophthalate binds to calcium ions in the bacterial cell wall, leading to inhibition of cell division. The biological activity of dimethyl 4-nitrophthalate can be measured by measuring the redox potential and calculating the constant, which is between -0.5 and -1.5 volts. This molecule also has strong anti-inflammatory properties due to its ability to reduce nitric oxide levels in macrophages.</p>
    Fórmula:C10H9NO6
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:239.18 g/mol

    Ref: 3D-FD70321

    250g
    134,00€
  • 4-Phenylbenzoic acid methyl ester

    CAS:
    4-Phenylbenzoic acid methyl ester is a bifunctional molecule that has been shown to be an effective antibacterial agent. It contains two oxadiazole moieties, which are structurally similar to sulfonamides and can form a stable amide bond with an amino group. The pharmacophore of 4-phenylbenzoic acid methyl ester is a four-member ring with two nitrogens and two carbons. This compound has been shown to have antibacterial properties by cleaving the magnesium bond in the enzyme methionine synthase, which catalyzes the formation of methionine from homocysteine and ATP. 4-Phenylbenzoic acid methyl ester is also able to cleave bonds in nonpolar solvents such as benzene, chloroform, and dichloromethane.
    Fórmula:C14H12O2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:212.24 g/mol

    Ref: 3D-FP48866

    1kg
    456,00€
    100g
    135,00€
    250g
    204,00€
    500g
    327,00€
  • 2'-Hydroxy-2,4,4'-trimethoxychalcone

    CAS:
    2'-Hydroxy-2,4,4'-trimethoxychalcone is a fine chemical that is used as a building block in research and development of pharmaceuticals. It is an intermediate for the production of drugs such as antibiotics, antiviral agents, and antifungals. 2'-Hydroxy-2,4,4'-trimethoxychalcone has also been shown to be useful for the synthesis of complex compounds with versatile applications.
    Fórmula:C18H18O5
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:314.33 g/mol

    Ref: 3D-FH66636

    1g
    336,00€
    100mg
    134,00€
    250mg
    180,00€
    500mg
    236,00€
  • Ethyl 7-hydroxycoumarin-3-carboxylate

    CAS:
    <p>Ethyl 7-hydroxycoumarin-3-carboxylate is a coumarin derivative that acts as a selective and potent inhibitor of the adenosine A3 receptor. It has been shown to inhibit growth of cancer cells in vitro, and it also inhibits the proliferation of S.aureus. Ethyl 7-hydroxycoumarin-3-carboxylate binds to the α subunit in an irreversible manner, inhibiting its function. This compound has been used to study plant physiology and homogeneous catalysis.</p>
    Fórmula:C12H10O5
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:234.2 g/mol

    Ref: 3D-FE45720

    1g
    598,00€
    2g
    1.042,00€
    100mg
    134,00€
    250mg
    229,00€
    500mg
    383,00€
  • Methyl 3-(4-hydroxyphenyl)benzoate

    CAS:
    <p>Please enquire for more information about Methyl 3-(4-hydroxyphenyl)benzoate including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C14H12O3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:228.24 g/mol

    Ref: 3D-FH43933

    2g
    236,00€
    5g
    355,00€
  • DL-Methionine-DL-sulfoximine

    CAS:
    <p>DL-Methionine sulfoximine is a drug that blocks the synthesis of glutathione, an important antioxidant and detoxifying agent. DL-Methionine sulfoximine may be useful in preventing or treating eye disorders, such as age-related macular degeneration and retinitis pigmentosa. It also has been shown to have beneficial effects in animal models of epilepsy, Alzheimer’s disease, Parkinson's disease, and stroke. DL-Methionine sulfoximine has been shown to have beneficial effects in animal models of epilepsy, Alzheimer’s disease, Parkinson's disease, and stroke. This drug is being studied for its potential use in metabolic disorders such as diabetes and obesity.</p>
    Fórmula:C5H12N2O3S
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:180.23 g/mol

    Ref: 3D-FM57660

    1g
    336,00€
    5g
    A consultar
    10g
    A consultar
    25g
    A consultar
    500mg
    236,00€
  • Crystal violet lactone

    CAS:
    <p>Crystal violet lactone is a hydroxylated derivative of crystal violet that has been shown to exist as a stable complex with metal chelates. The chemical stability of this compound is related to the presence of the hydroxyl group, which can be used to form hydrogen bonding interactions. Crystal violet lactone has been shown to react with p-hydroxybenzoic acid in an electron transfer reaction, resulting in the formation of stable complexes. This chemical property makes it useful for flow assays, such as those used for the detection of glucose in blood plasma.</p>
    Fórmula:C26H29N3O2
    Pureza:Min. 95%
    Cor e Forma:Yellow Powder
    Peso molecular:415.53 g/mol

    Ref: 3D-FC02855

    1kg
    975,00€
    2kg
    1.551,00€
    100g
    306,00€
    250g
    511,00€
    500g
    728,00€
  • (R)-BoroLeu-(+)-pinanediol-trifluoroacetate

    CAS:
    <p>(R)-BoroLeu-(+)-pinanediol-trifluoroacetate is a complex compound with CAS No. 179324-87-9 and can be used as a reagent, useful intermediate, or fine chemical. It is a versatile building block that can be used in the synthesis of speciality chemicals, research chemicals, and reaction components. This compound has been reported to be a useful scaffold for the synthesis of novel compounds that could have applications in medicine, such as anti-cancer drugs and antibiotics.</p>
    Fórmula:C17H29BF3NO4
    Cor e Forma:White Off-White Powder
    Peso molecular:379.22 g/mol

    Ref: 3D-FB36621

    10g
    341,00€
    25g
    607,00€
    50g
    920,00€
    100g
    A consultar
    250g
    A consultar
  • (1R,2R,3S,5R)-Pinanediol pyrrolidine-2S-boronate hydrochloride

    CAS:
    <p>(1R,2R,3S,5R)-Pinanediol pyrrolidine-2S-boronate hydrochloride is a reagent that can be used in the synthesis of complex compounds. It is a fine chemical with CAS No. 149716-73-4. (1R,2R,3S,5R)-Pinanediol pyrrolidine-2S-boronate hydrochloride has a number of uses including as an intermediate for the preparation of speciality chemicals and as a building block for reactions in research. This compound is also useful as a versatile building block for many reactions.</p>
    Fórmula:C14H25BClNO2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:285.62 g/mol

    Ref: 3D-FP27050

    5mg
    384,00€
    10mg
    506,00€
    25mg
    872,00€
  • 3,5-Diiodo-4(4'-methoxyphenoxy)benzoic acid methyl ester

    CAS:
    <p>3,5-Diiodo-4(4'-methoxyphenoxy)benzoic acid methyl ester (DIMBOA) is a hormone analogue that inhibits the growth of cancer cells by interfering with mitochondrial function. DIMBOA binds to the mitochondria of animal cells and prevents adenosine triphosphate (ATP) production. DIMBOA also blocks the synthesis of DNA and RNA in animal cells, which may be due to its ability to interfere with enzyme activities such as protein synthesis, cell proliferation, and apoptosis. 3,5-Diiodo-4(4'-methoxyphenoxy)benzoic acid methyl ester has been shown to inhibit cellular growth by autophagy. This drug has been shown to have no adverse effects on normal fibroblasts or antigen presenting cells in animals.</p>
    Fórmula:C15H12I2O4
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:510.06 g/mol

    Ref: 3D-FD67053

    50mg
    135,00€
    100mg
    149,00€
    250mg
    254,00€
    500mg
    356,00€
  • 3-(4-Nitrophenyl)-1-adamantanecarboxylic acid

    CAS:
    <p>3-(4-Nitrophenyl)-1-adamantanecarboxylic acid is a high quality, versatile building block compound that has been used as a reagent and as a useful intermediate. This product is commercially available and can be used in the synthesis of complex compounds with many different applications, such as pharmaceuticals, pesticides, dyes, and photographic chemicals. It is also a useful scaffold for the production of speciality chemicals and research chemicals. 3-(4-Nitrophenyl)-1-adamantanecarboxylic acid has been used in reactions involving electron transfer, nucleophilic substitution, and condensation reactions.</p>
    Fórmula:C17H19NO4
    Pureza:Min. 95%
    Peso molecular:301.34 g/mol

    Ref: 3D-FN67095

    1g
    135,00€
    2g
    143,00€
    5g
    203,00€
    10g
    320,00€
    25g
    535,00€
  • Betaine monohydrate

    CAS:
    <p>Betaine is a group P2 compound that is an organic acid. It has been shown to improve the performance of polymerases, which are enzymes in cells that are responsible for synthesizing DNA. Betaine also helps with energy metabolism and in the synthesis of fatty acids. This compound can be found in plants and animals, as well as being manufactured synthetically. The melting point of betaine is between -6°C (21.2°F) and -13°C (8.6°F). When this compound is dissolved in water, it undergoes a phase transition from a solid state to a liquid state at its melting point. The boiling point of betaine is between 148°C (300.4°F) and 149°C (301.2°F). Betaine interacts with other molecules through hydrogen bonding interactions or by forming an acid-complex with sodium carbonate or malonic acid.</p>
    Fórmula:C5H11NO2·H2O
    Cor e Forma:White Powder
    Peso molecular:135.16 g/mol

    Ref: 3D-FB31874

    1kg
    235,00€
    2kg
    398,00€
    5kg
    745,00€
    10kg
    1.228,00€
    25kg
    2.307,00€
  • Maytansinoid DM 4

    CAS:
    <p>N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)-maytansine (DMAP) is a structural analogue of maytansinoids that has potent antitumor activity against renal cell cancer. DMAP binds to the active site of wild type enzyme, and inhibits its activity. DMAP also inhibits the activities of other enzymes that are involved in the synthesis of proteins and other cellular components. The inhibition of these enzymes by DMAP leads to tumor cell death. This drug was found to be more cytotoxic at higher doses than the parent compound, maytansinol, which indicates that DMAP has a higher affinity for its target enzyme. The cytotoxicity of this drug is not affected by platinum resistance in ovarian cancer cells or by P-glycoprotein (Pgp) inhibitors such as verapamil and cyclosporin A.</p>
    Fórmula:C38H54ClN3O10S
    Pureza:Min. 95%
    Cor e Forma:Off-White Powder
    Peso molecular:780.37 g/mol

    Ref: 3D-FD36534

    5mg
    222,00€
    10mg
    344,00€
    25mg
    607,00€
    50mg
    1.045,00€
    100mg
    1.667,00€
  • Dimethyl 3-nitrophthalate

    CAS:
    <p>Dimethyl 3-nitrophthalate is a synthetic compound that can be used in catalytic reactions. It has been shown to catalyze the conversion of acetaldehyde and hydrochloric acid to 3-hydroxypropionaldehyde with dehydrogenation as the main reaction mechanism. This reaction is followed by the addition of persulfate to give dimethyl 3-nitrophthalate sulfoxide, which can then be converted into dimethyl 3-nitrophthalate with boron trifluoride etherate and ammonium persulfate. The anticancer potential of this compound has been demonstrated in vitro using tyrosine kinase as a model enzyme. Dimethyl 3-nitrophthalate also binds to specific receptors such as those found on neutrophils, macrophages, and T cells.</p>
    Fórmula:C10H9NO6
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:239.18 g/mol

    Ref: 3D-FD69915

    25g
    345,00€
    50g
    492,00€
    100g
    804,00€
    250g
    1.515,00€
    500g
    2.213,00€
  • trans,trans-Farnesyl thiosalicylic acid

    CAS:
    <p>Farnesyl thiosalicylic acid (FTSA) is a synthetic compound that exhibits potent anticancer activity. FTSA binds to the active site of the enzyme protein kinase C-alpha (PKC-α), which prevents its phosphorylation and activation. This prevents the activation of the mitogen-activated protein kinases, which are involved in cell proliferation and differentiation. FTSA also inhibits cancer cell migration by blocking MMP-9 activity, leading to tumor regression. FTSA has been shown to be effective against chemotherapy resistant breast cancer cells, as well as cancer cells from other tissues such as colon, prostate, and ovary.</p>
    Fórmula:C22H30O2S
    Pureza:Min. 95%
    Cor e Forma:White to off-white solid.
    Peso molecular:358.54 g/mol

    Ref: 3D-FF23230

    5mg
    140,00€
  • Fmoc-3,5-diiodo-D-tyrosine

    CAS:
    <p>Please enquire for more information about Fmoc-3,5-diiodo-D-tyrosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C24H19I2NO5
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:655.22 g/mol

    Ref: 3D-FF49652

    1g
    291,00€
    2g
    437,00€
    5g
    806,00€
  • alpha-Naphthyl butyrate

    CAS:
    <p>Alpha-naphthyl butyrate is a monomer of polybutyrate and is used as an intermediate in the production of polybutylene terephthalate. This product is also used for biological studies and has been shown to have acute toxicities. Alpha-naphthyl butyrate has been shown to inhibit esterase and enzyme activities, and it is more toxic than butyric acid. Alpha-naphthyl butyrate can be used for the diagnosis of certain types of chronic viral hepatitis, such as hepatitis B virus or hepatitis C virus, by detecting human immunoglobulin G (IgG) antibodies against this compound.</p>
    Fórmula:C14H14O2
    Pureza:Min. 95%
    Cor e Forma:Clear Liquid
    Peso molecular:214.26 g/mol

    Ref: 3D-FN69862

    25g
    203,00€
  • 3'-Fluoro-4'-methoxy-beta-methyl-beta-nitrostyrene

    CAS:
    <p>3'-Fluoro-4'-methoxy-beta-methyl-beta-nitrostyrene is a reactive building block that can be used in the synthesis of many different compounds. It is a fine chemical and a reagent which is useful in organic chemistry. 3'-Fluoro-4'-methoxy-beta-methyl-beta-nitrostyrene is used as a reaction component for the synthesis of many different compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. It has CAS number 1023717-11-4 and can be used as an intermediate compound or building block for the production of complex compounds.</p>
    Fórmula:C10H10FNO3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:211.19 g/mol

    Ref: 3D-FF66233

    1g
    184,00€
    2g
    258,00€
    500mg
    134,00€
  • O-(4-Nitrophenyl)hydroxylamine

    CAS:
    <p>O-(4-Nitrophenyl)hydroxylamine (OPH) is an enantioselective, catalytic, and thermal stable reagent for the synthesis of chiral methyl groups. OPH can be used as a nucleophile to convert electron-deficient alkenes into α-chloroalkenes. It also reacts with nitroarenes to give nitroalkenes in high yields. OPH has been shown to be effective in the asymmetric hydrolysis of esters and amides through its ability to oxidize the methyl group on the substrate. This reaction does not occur with other groups such as hydroxyl or hydrogen atoms.<br>Methyl groups are important for many biological molecules, including proteins and nucleic acids, which form the backbone of cells that make up living organisms. The OPH reaction is catalyzed by enzymes called methyltransferases, which transfer one atom of methyl from S-adenosylmethionine (SAM)</p>
    Fórmula:C6H6N2O3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:154.12 g/mol

    Ref: 3D-FN143791

    1g
    243,00€
    2g
    376,00€
    5g
    657,00€
  • 13-cis-Retinoic acid

    Produto Controlado
    CAS:
    <p>An endogenous retinoic acid receptor (RAR) agonist that upregulates forkhead box class O (FoxO) transcription factor. Suppresses activity and proliferation of sebaceous glands. Used for treating nodulocystic acne. Induces differentiation, neurite outgrowth and inhibits proliferation of neuroblastoma cells. A potential chemopreventive agent in non-small cell lung cancer, head and neck squamous cell carcinoma and neuroblastoma.</p>
    Fórmula:C20H28O2
    Pureza:Min. 97 Area-%
    Cor e Forma:Yellow Powder
    Peso molecular:300.44 g/mol

    Ref: 3D-FR27714

    25g
    218,00€
    50g
    341,00€
    100g
    486,00€
    250g
    729,00€
    500g
    863,00€
  • 3-Chloro-7-hydroxy-4-methylcoumarin

    CAS:
    <p>3-Chloro-7-hydroxy-4-methylcoumarin is a Michaelis–Menten kinetics inhibitor that binds to the bacterial 16S ribosomal RNA and inhibits transcription and protein synthesis. This compound has been studied for wastewater treatment, where it was shown to be effective in treating sodium citrate. 3-Chloro-7-hydroxy-4-methylcoumarin is also used as an inhibitor of coumarin derivatives, which are compounds that have been shown to have antiinflammatory properties. 3CMC inhibits transcription by binding to the polymerase chain reaction (PCR) product. It has also been shown to bind to the nonpolar solvent, which prevents the formation of a complex with the enzyme DNA gyrase, leading to cell death by inhibiting protein synthesis. Fluorescence techniques have been used to study this type of inhibition in a model system.</p>
    Fórmula:C10H7ClO3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:210.61 g/mol

    Ref: 3D-FC137950

    5g
    192,00€
    10g
    321,00€
    25g
    501,00€
  • 4-Ethoxysalicylic acid

    CAS:
    <p>4-Ethoxysalicylic acid is a phosphorus oxychloride derivative that is used as an intermediate in the production of xanthones. Xanthones are used in the manufacture of dyes, pharmaceuticals, and fragrances. This compound also reacts with zinc chloride to give 4-ethoxysalicylate, which is an oxidizing agent. 4-Ethoxysalicylic acid has low toxicity and can be filtered from a reaction mixture by filtration or recrystallization. It can act as a monoamine oxidase inhibitor, which may contribute to its antidepressant properties. A hydrophobic molecule, 4-ethoxysalicylic acid will not dissolve in water but can be dissolved in organic solvents such as alcohols or ethers. It also has a high affinity for blood proteins and will bind to them readily. This property makes it useful as an anti-coagulant drug for treating depression and other mental illness.</p>
    Fórmula:C9H10O4
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:182.17 g/mol

    Ref: 3D-FE68094

    25g
    325,00€
    50g
    502,00€
  • 4-Methoxycinnamylidene acetaldehyde

    CAS:
    <p>4-Methoxycinnamylidene acetaldehyde is a versatile building block with a CAS number of 27394-81-6. It is used in the research and production of fine chemicals, pharmaceuticals, and high quality reagents. 4-Methoxycinnamylidene acetaldehyde can be used as a useful scaffold for the synthesis of complex compounds. This building block is also a useful intermediate in organic chemistry reactions.</p>
    Fórmula:C12H12O2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:188.22 g/mol

    Ref: 3D-FM66809

    1g
    450,00€
    2g
    735,00€
    500mg
    280,00€
  • L-Aspartic β-7-amido-4-methylcoumarin

    CAS:
    <p>L-Aspartic acid beta-7-amido-4-methylcoumarin (LAM) is a fluorescent amino acid that can be used to diagnose deficiencies of this amino acid. LAM is an experimental diagnostic chemical and has been tested in rats, rabbits, and humans. It is a fluorescent amino acid that binds to the 7th position on lysine residues in proteins. The binding of the fluorophore to the protein can be detected using fluorescence spectroscopy. The assay measures the intensity of fluorescence at 480 nm and 660 nm which corresponds to excitation at 320 nm and 420 nm respectively. LAM is currently being studied as a potential treatment for cancerous cells and their growth.</p>
    Fórmula:C14H14N2O5
    Pureza:Min. 99 Area-%
    Cor e Forma:White Powder
    Peso molecular:290.27 g/mol

    Ref: 3D-FA48654

    10mg
    204,00€
    25mg
    341,00€
    50mg
    486,00€
    100mg
    729,00€
    250mg
    1.086,00€
  • 3'-Acetoxyacetophenone

    CAS:
    <p>3'-Acetoxyacetophenone is a chemical compound with the molecular formula C8H10O2. It has a melting point of 129-130°C, and a boiling point of 206°F. The compound is soluble in alcohols and ethers, but insoluble in water. 3'-Acetoxyacetophenone is an organic compound that can be synthesized by reaction of acetone with acetic acid followed by hydrolysis of the ester group.<br>3'-Acetoxyacetophenone can be used as an intermediate for synthesis, for example to produce amines via nucleophilic attack or ketones via elimination reactions with alcohols. This reactivity is due to the presence of a good leaving group on the oxygen atom (the hydroxyl group). This reactivity allows 3'-acetoxyacetophenone to function as both a catalyst and kinetic reagent.</p>
    Fórmula:C10H10O3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:178.18 g/mol

    Ref: 3D-FA50803

    100g
    134,00€
    250g
    204,00€
  • 2,2'-Dimethylbibenzyl

    CAS:
    <p>2,2'-Dimethylbibenzyl is a chemical compound that has been used as a precursor for the synthesis of other chemicals. It can be synthesized by reacting dodecyl chloride with an aryl halide, then reacting the product with anhydrous hydroxyl group in the presence of a radical coupling agent. The reaction products are chlorosulfonic acid and 2,2'-dimethylbibenzyl. This chemical compound is a strong electron acceptor and can help to produce radical coupling reactions. It also reacts with protonated water to form sulfoxide and trifluoroacetic acid.</p>
    Fórmula:C16H18
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:210.31 g/mol

    Ref: 3D-FD62612

    10g
    252,00€
    25g
    474,00€
  • 4-Phenoxycinnamic acid

    CAS:
    <p>4-Phenoxycinnamic acid is a useful scaffold and building block in organic chemistry. It is a versatile chemical intermediate with a CAS number of 2215-83-0, often used in the synthesis of other molecules. 4-Phenoxycinnamic acid has recently been shown to be an effective reagent for the conversion of nitrobenzene to benzyl alcohols, which are useful in the production of pharmaceuticals. This compound can also be used as a high-quality research chemical and as a speciality chemical for use in laboratory experimentation.</p>
    Fórmula:C15H12O3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:240.25 g/mol

    Ref: 3D-FP67765

    1g
    291,00€
    2g
    437,00€
    5g
    719,00€
    250mg
    135,00€
    500mg
    182,00€
  • Isobavachalcone

    CAS:
    <p>Isobavachalcone is a natural compound that belongs to the group of flavonoids. It has been shown to be cytotoxic at high concentrations (e.g., 50 μM) in HL-60 cells and induce apoptosis by increasing the expression of pro-apoptotic proteins. Isobavachalcone also has anti-inflammatory properties, which may be due to its ability to inhibit the production of reactive oxygen species and increase the expression of nuclear DNA binding protein DDB2. Isobavachalcone can be used as an analytical tool for determining mitochondrial membrane potential and for identifying compounds with autophagic activity.</p>
    Fórmula:C20H20O4
    Pureza:Min. 98 Area-%
    Peso molecular:324.37 g/mol

    Ref: 3D-FI73915

    10mg
    135,00€
    25mg
    143,00€
  • 3,3',5-Triiodo-L-thyronine

    CAS:
    <p>Triiodothyronine (T3) is a thyroid hormone that has a high affinity for the thyrotropin receptor. It regulates the metabolic rate, cell specific transcriptional regulation, and transcriptional regulation of genes involved in fatty acid synthesis. T3 is synthesized from the amino acid tyrosine through a series of reactions catalyzed by enzymes such as tyrosine hydroxylase, thyroperoxidase, and type 2 iodothyronine deiodinase. The enzyme thyroid peroxidase converts inactive T3 to the active form of T3 (triiodothyronine). In addition, triiodothyronine can be converted to reverse T3 (rT3), which is inactive. Triiodothyronine has an optimal ph of 7.4-8.0 and an optimum igf-i concentration of 100 ng/ml, where it can stimulate growth hormone release from the anterior pituitary gland.</p>
    Fórmula:C15H12I3NO4
    Pureza:Min. 95 Area-%
    Cor e Forma:Off-White Powder
    Peso molecular:650.97 g/mol

    Ref: 3D-FT28506

    1g
    378,00€
    2g
    523,00€
    5g
    796,00€
    10g
    1.000,00€
    500mg
    224,00€
  • 4-Nitrophthalic acid

    CAS:
    <p>4-Nitrophthalic acid is a white crystalline solid that has an acid and basic character. It has been shown to be antigenic, with a specific antibody able to bind to the 4-nitro group. The structure of 4-Nitrophthalic acid was determined using X-ray crystallography and NMR spectroscopy. The molecular weight of 4-Nitrophthalic acid is 177.2 g/mol, with a melting point of 174 °C and a boiling point of 341 °C. It is soluble in water and organic solvents such as ethanol, acetone, chloroform, ethyl ether, benzene, hexane, dichloromethane and ethyl acetate.</p>
    Fórmula:C8H5NO6
    Pureza:Min. 97 Area-%
    Cor e Forma:White Powder
    Peso molecular:211.13 g/mol

    Ref: 3D-FN03461

    1kg
    195,00€
    5kg
    456,00€
    10kg
    729,00€
    500g
    135,00€
  • Anthracene

    CAS:
    <p>Anthracene is a fluorescent probe that is used in the detection of hydrochloric acid. The fluorescence intensity of anthracene changes when it interacts with HCl, which makes it a good indicator for detecting this acid. Anthracene has been shown to bind to the bacterial cell wall skeleton and inhibit detoxification enzymes, such as beta-glucuronidase and beta-lactamase. This inhibition can be used to measure the activity of these enzymes. Anthracene has also been shown to have transport properties in inflammatory bowel disease (IBD). Protocatechuic acid has been shown to increase the solubility of anthracene in experimental conditions.</p>
    Fórmula:C14H10
    Pureza:(Hplc) Min. 98.5%
    Cor e Forma:Powder
    Peso molecular:178.23 g/mol

    Ref: 3D-FA01372

    1kg
    921,00€
    50g
    245,00€
    100g
    291,00€
    250g
    478,00€
    500g
    607,00€
  • 1-(2',3'-Difluorophenyl)-2-nitroethene

    CAS:
    <p>1-(2',3'-Difluorophenyl)-2-nitroethene (1,2-DFNE) is a speciality chemical that is used as an intermediate for the synthesis of a wide variety of organic compounds. It has been found to be a useful scaffold for the synthesis of complex compounds and can also be used as a building block for the synthesis of fine chemicals, research chemicals, and versatile building blocks. 1,2-DFNE is soluble in many organic solvents and can be handled without special precautions. This reagent is a high quality compound with purity greater than 99%.</p>
    Fórmula:C8H5F2NO2
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:185.13 g/mol

    Ref: 3D-FD66660

    1g
    135,00€
    2g
    205,00€
    5g
    308,00€
  • 3-Chloro-4-methoxybenzoic acid methyl ester

    CAS:
    <p>3-Chloro-4-methoxybenzoic acid methyl ester is a potent antiproliferative agent that inhibits the growth of cancer cells and bacteria. It is an amide, which has been synthesized by equilibration between two equivalents of 3-chlorobenzoic acid and methylamine. The copulatory proton profile for this compound has been determined using liquid chromatography with mass spectrometry detection (LCMS). This compound is also a weak inhibitor of tyrosine kinases, but is more potent as an inhibitor of protein kinase C. Sorafenib and dasatinib are examples of compounds that have been shown to be linked to this drug. 3-Chloro-4-methoxybenzoic acid methyl ester can induce the production of TNF-α in thp-1 cells at micromolar concentrations.</p>
    Fórmula:C9H9ClO3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:200.62 g/mol

    Ref: 3D-FC70578

    25g
    135,00€
    50g
    150,00€
    100g
    208,00€
    250g
    376,00€
  • 5-Hydroxyaloin a 6'-o-acetate

    CAS:
    <p>5-Hydroxyaloin A 6'-O-acetate is a naturally occurring polysubstituted anthraquinone glycoside, which is derived primarily from Aloe species. It is synthesized through biosynthetic pathways in the Aloe vera plant, where anthraquinones are acetylated to enhance their biological activity. This compound is known for its potential bioactive properties, including anti-inflammatory and antioxidant activities, which are attributed to its ability to modulate various biochemical pathways.</p>
    Fórmula:C23H24O11
    Pureza:Min. 95%
    Peso molecular:476.43 g/mol

    Ref: 3D-FH165631

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  • L-Leucine b-naphthylamide hydrochloride

    CAS:
    <p>Please enquire for more information about L-Leucine b-naphthylamide hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C16H20N2O·HCl
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:292.8 g/mol

    Ref: 3D-FL48207

    1g
    300,00€
    2g
    430,00€
    5g
    538,00€
    500mg
    193,00€