Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(274.925 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.874 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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4-Hydroxy-N-desbutyl Bupivacaine
CAS:Produto Controlado<p>Applications Bupivacaine metabolite.<br>References Goehl, T. J. et al.: Xenobiotica 3, 761 (1973)<br></p>Fórmula:C14H20N2O2Cor e Forma:NeatPeso molecular:248.32Butropium Bromide
CAS:<p>Applications Anticholinergic. Antispasmodic.<br>References Fujita, et al.: J. Labelled Compd., 9, 149 (1972), Tanaka, et al.: J. Pharm. Soc. Jpn., 92, 510 (1972), Kawamoto H., et al.: Arzneim.-Forsch., 35, 1475 (1985),<br></p>Fórmula:C28H38NO4·BrCor e Forma:NeatPeso molecular:532.51Cresyl Diphenyl Phosphate-d7 Isomer 1
CAS:Produto Controlado<p>Applications Cresyl Diphenyl Phosphate-d7 Isomer 1 is the deuterated form of Cresyl Diphenyl Phosphate (C783015), which is a phosphorus flame retardant additive.<br>References van der Veen., et al.: Chemosphere, 88, 1119 (2012);<br></p>Fórmula:C19D7H10O4PCor e Forma:NeatPeso molecular:347.353Abiraterone Ethyl Ether
CAS:Produto Controlado<p>Applications Abiraterone Ethyl Ether is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Fórmula:C26H35NOCor e Forma:NeatPeso molecular:377.569-Deschloro-9-bromo Beclomethasone Dipropionate
CAS:Produto Controlado<p>Impurity Beclomethasone Dipropionate EP Impurity D<br>Applications 9-Deschloro-9-bromo Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity D) is an impurity of Beclomethasone Dipropionate (B131030).<br>References Shou, M. et al.: J. Pharmac. Biomed. Anal., 50, 356 (2009); Johnston, S. et al.: J. Chrom. Sci., 48, 733 (2010);<br></p>Fórmula:C28H37BrO7Cor e Forma:NeatPeso molecular:565.49(±)-Hexanoylcarnitine Chloride
CAS:Produto ControladoFórmula:C13H26NO4•ClCor e Forma:NeatPeso molecular:260.3535457-Ethyl Camptothecin
CAS:<p>Impurity Irinotecan USP Related Compound E<br>Applications An anticancer drug, showed strong activity against various murine tumors. A Camptothecin (CPT) derivative as antineoplastic agent against drug-resistant tumors. Irinotecan USP Related Compound E.<br>References Brangi, M., et al.: Cancer Res., 59 5938 (1999), Miyake, K., et al.: Cancer Res., 59, 8 (1999) , Bom, D., et al.: J. Med. Chem., 43, 3970 (2000) , Gamcsik, M., et al.: Mol. Cancer Ther., 1, 11 (2001).<br></p>Fórmula:C22H20N2O4Cor e Forma:Light YellowPeso molecular:376.41β-(m-Hydroxyphenyl)hydracrylic Acid
CAS:Produto Controlado<p>Applications β-(m-Hydroxyphenyl)hydracrylic Acid is a urinary metabolite of phenylalanine from the Clostridium gram-positive bacteria cell line. Urinary metabolite of Rutin (R701800), a capillary protectant in plants.<br>References Harrison, et al.: J. Am. Pharm. Assoc., 39, 557 (1950), Humphreys, et al.: Econ. Bot., 18, 195 (1964), Khalifa, T.I., et al.: Anal. Profiles Drug Subs., 12, 623 (1983); Shigeo, B. et al.: J. Pharm. Sci., 72, 1155 (1983)<br></p>Fórmula:C9H10O4Cor e Forma:NeatPeso molecular:182.17Propionyl Glycine
CAS:Produto Controlado<p>Applications A metabolite of methylmalonic acid and propionic acid in children with methylmalonic acid and propionic acid metabolic disorders.<br>References Duran, M., et al.: Clin. Chimica Acta, 82, 93 (1978), Thompson, G.N., et al.: Pediatric Res., 27, 413 (1990),<br></p>Fórmula:C5H9NO3Cor e Forma:NeatPeso molecular:131.13Methyl Isofenphos (Technical Grade)
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Methyl Isofenphos is an organophosphorus compound, that according to biological studies, can cause acute toxicity to animals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Li, S.: Huanjing Wuran Yu Fangzhi, 20, 13 (1998); Yin, Y., et al.: Huanjing Yu Jiankang Zazhi, 28, 583 (2011)<br></p>Fórmula:C14H22NO4PSCor e Forma:ColourlessPeso molecular:331.37Ethyl 2-Bromoisovalerate
CAS:<p>Applications Ethyl 2-Bromoisovalerate (cas# 609-12-1) is a compound useful in organic synthesis.<br></p>Fórmula:C7H13BrO2Cor e Forma:NeatPeso molecular:209.08Nor Cholic Acid
CAS:Produto Controlado<p>Applications A novel bile acid, an analogue of Cholic acid (C432600).<br>References Yamaga, N., et al.: J. Biochem., 116, 1123 (1994),<br></p>Fórmula:C23H38O5Cor e Forma:NeatPeso molecular:394.54N,N-bis(1-naphthylmethyl)aminomethane
CAS:Produto Controlado<p>Applications N-Methyl-N-(1-naphthalenylmethyl)-1-naphthalenemethanamine is a reagent used in the synthesis of Butenafine Hydrochloride (B690195) an anti-fungal.<br>References Maeda, T., et al.: Yakugaku Zasshi, 111, 126 (1991).<br></p>Fórmula:C23H21NCor e Forma:NeatPeso molecular:311.42Pyochelin I and Pyochelin II
CAS:Produto Controlado<p>Impurity 2.5<br>Applications Pyochelin I and Pyochelin II are the two major siderophores produced and secreted by Pseudomonas aeruginosa PAO1 to assimilate iron. It also has trphenyltin (T809350) decomposition capacity.<br>References Braud, A., et al.: J. Bacteriol., 191, 3517 (2009); Sun, G., et al.: Appl. Environ. Microb., 72, 7264 (2006)<br></p>Fórmula:C14H16N2O3S2Cor e Forma:NeatPeso molecular:324.425-Oxo Atorvastatin
CAS:<p>Applications Atorvastatin Derivative<br></p>Fórmula:C33H33FN2O5Cor e Forma:NeatPeso molecular:556.62Enzalutamide Carboxylic Acid
CAS:<p>Applications Enzalutamide Carboxylic Acid is used as hormone therapies to prevent androgen-fuled growth of castrate-resistant prostate cancer.<br>References Tomasz, M.B., et al.: New Engl, J. Med., 424, 371 (2014);<br></p>Fórmula:C20H13F4N3O3SCor e Forma:NeatPeso molecular:451.39Naphthalene-2-sulfonic Acid Hydrate
CAS:<p>Applications Naphthalene-2-sulfonic acid (cas# 120-18-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C10H8O3SCor e Forma:NeatPeso molecular:208.234N'-Methyl-N,N-diphenylurea
CAS:<p>Impurity Temozolomide USP Related Compound B<br>Applications N'-Methyl-N,N-diphenylurea is used in the stabilization of thermal propellants. Temozolomide USP Related Compound B.<br>References Bohn, M. et al.: Prop. Exp. Pyro.,et al.: 19, 266 (1994); Muthurajan, H. et al.: J. Hazard. Mat., 133, 30 (2006);<br></p>Fórmula:C14H14N2OCor e Forma:NeatPeso molecular:226.27trans-Hydroxy Perhexiline (Mixture of Diastereomers)
CAS:Produto ControladoFórmula:C19H35NOCor e Forma:NeatPeso molecular:293.49Dihydro Caffeic Acid 3-O-Sulfate Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Caffeic Acid. Metabolite profiling of hydroxycinnamate derivatives in plasma and urine after the ingestion of coffee by humans: identification of biomarkers of coffee consumption.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>Fórmula:C9H8Na2O7SCor e Forma:NeatPeso molecular:306.20N-Acetyl Desethyl Chloroquine-d4
CAS:Produto Controlado<p>Applications A labelled Chloroquine metabolite, also an intermediate in the preparation of labelled Chloroquine It is a COVID19-related research product.<br>References Brown, N., et al.: J. Chromatogr., Biomed. App., 309, 426 (1984), Nord, K., et al.: Int. J. Pharm., 72, 11 (1991),<br></p>Fórmula:C18D4H20ClN3OCor e Forma:NeatPeso molecular:337.88D,L-N,N-Didesmethyl-O-desmethyl Venlafaxine Hydrochloride
CAS:<p>Applications A metabolite of Venlafaxine.<br></p>Fórmula:C14H22ClNO2Cor e Forma:NeatPeso molecular:271.781,2-Dihydro Desoxymetasone
CAS:Produto Controlado<p>Applications A metabolite of Desoxymetasone (D296970).<br>References Schriks, M., et al.: Environ. Sci. Technol., 44, 4766 (2010), Baeck, M., et al.: Eur. J. Dermatol., 20, 102 (2010), Lee, P., et al.: Bioorg. Med. Chem. Lett., 20, 69 (2010),<br></p>Fórmula:C22H31FO4Cor e Forma:NeatPeso molecular:378.48Simvastatin Dimer Impurity
CAS:Fórmula:C50H76O10Cor e Forma:White To Light YellowPeso molecular:837.13cis-4-Hydroxycinnamic Acid
CAS:Produto Controlado<p>Applications An antioxidative active compound isolated from the EtOAc layer of MeOH extracts of kochujang, Korean fermented red pepper paste. Photoisomerization of ionic liquid ammonium cinnamates. Cinnamic acids upon irradiation in solution undergo geometric isomerization while dimerizing to different dimers in the crystalline state.<br>References Armstrong, D., et al.: Anal. Chem., 73, 3679 (2001), Karmakar, B., et al.: J. Biotech., 80, 195 (2000),<br></p>Fórmula:C9H8O3Cor e Forma:NeatPeso molecular:164.16Beta-Estradiol 17-(Beta-D-Glucuronide) Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications beta-Estradiol 17-(beta-D-glucuronide) sodium salt is a glucocorticosteroid analog.<br></p>Fórmula:C24H31NaO8Cor e Forma:NeatPeso molecular:470.493-Hydroxy Loratadine
CAS:Produto Controlado<p>Applications An intermediate for the preparation of 3-Hydroxy Desloratadine.<br></p>Fórmula:C22H23ClN2O3Cor e Forma:NeatPeso molecular:398.88Methyl 1-Naphthaleneacetate
CAS:<p>Applications Methyl 1-naphthaleneacetate (cas# 2876-78-0) is a useful research chemical.<br></p>Fórmula:C13H12O2Cor e Forma:NeatPeso molecular:200.23Bis(4-cyanophenyl)methanol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications A metabolite of Letrozole.<br>References Koyama, E., et al.: Ther. Drug Monit., 15, 224 (1993), Pfister, C., et al.: J. Pharm. Sci., 83, 520 (1994), Vander H.Y., et al.: J. Pharm. Biomed. Anal., 24, 723 (2001), Cohen, M., et al.: Clin. Cancer Res., 8, 665 (2002),<br></p>Fórmula:C15H10N2OCor e Forma:NeatPeso molecular:234.25D-Tyrosine-d2
CAS:Produto Controlado<p>Applications D-Tyrosine-d2 is deuterium labelled D-Tyrosine (T899970). D-Tyrosine, the stereoisomer to L-Tyrosine (T899975), is an amino acid used in various organic syntheses for antibiotics. It is used in the synthesis of (-)-anisomycin, as well as BATSI (boronic acid transition state inhibitors) which act on β-lactamases. It has also been studied as an inhibitor of microbial growth on surfaces, reducing microbial attachment to hydrophillic glass and hydrophobic polypropylene surfaces.<br>References Li, Ji. et al.: Chin. Chem. Lett., 23, 647 (2012); Xu, H. et al.: Water Res., 45, 5796 (2011); Ke, W. et al.: Antimicrob. Agents Chemother., 55, 174 (2011)<br></p>Fórmula:C9D2H9NO3Cor e Forma:NeatPeso molecular:183.2Atorvastatin Methyl Ester
CAS:Produto Controlado<p>Applications Atorvastatin impurity. Atorvastatin Methyl Ester<br>References Graul, A., et al.: Drugs Future, 22, 956 (1997),<br></p>Fórmula:C34H37FN2O5Cor e Forma:White To Off-WhitePeso molecular:572.672-Aminoanthracene
CAS:Produto Controlado<p>Stability Air Sensitive<br>Applications 2-AMINOANTHRACENE (cas# 613-13-8) is a useful research chemical.<br></p>Fórmula:C14H11NCor e Forma:NeatPeso molecular:193.24all-trans 5,6-Epoxy Retinoic Acid
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of all-trans Retinoic acid (R250200).<br>References Idres, N., et al.: Cancer Res., 61, 700 (2001), Taimi, M., et al.: J. Biol. Chem., 279, 77 (2004), Vermot, J., et al.: Science, 308, 563 (2005),<br></p>Fórmula:C20H28O3Cor e Forma:Light YellowPeso molecular:316.437-Hydroxy-1,3,6-naphthalenetrisulfonic Acid Trisodium
CAS:<p>Applications 7-Hydroxy-1,3,6-naphthalenetrisulfonic Acid is a pollutant that is found in waste water.<br>References Cristiano, N., et al.: Ind, Eng. Chem. Res., 46, 6674 (2007)<br></p>Fórmula:C10H5O10S3·3NaCor e Forma:NeatPeso molecular:450.30(-)-β-Sesquiphellandrene
CAS:Produto Controlado<p>Applications (-)-β-Sesquiphellandrene are found in Tanacetum vulgare plants. It is also an essential leaf and flower oils in Heracleum species.<br>References Clancy, M. V., et al.: Sci. Rep., 6, 38087 (2016); Usjak, L., et al.: Food Funct., 8, 278-290 (2017);<br></p>Fórmula:C15H24Cor e Forma:ColourlessPeso molecular:204.353,3'-[Oxybis(3,1-propanediyloxy)]bis[1-propanol]
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3,3'-[Oxybis(3,1-propanediyloxy)]bis[1-propanol] is derived from 3-(Benzyloxy)propyl 4-Toluenesulfonate (B288830), which is used as a reagent in the synthesis of Silodosin (S465000); an antidysuria drug. 3-(Benzyloxy)propyl 4-Toluenesulfonate is also used as a reagent in the preparation of aryloxyalkyl derivatives of adenine which have antiviral activity.<br>References Calogero, F., et al.: Eur. J. Org. Chem., 2015, 6011 (2015); Petrov, V.I., et al.: Chem. Heterocyc. Compd., 39, 1218 (2003)<br></p>Fórmula:C12H26O5Cor e Forma:NeatPeso molecular:250.33Lauric Acid-d3
CAS:Produto Controlado<p>Applications Lauric Acid-d3, is the labeled analogue of Lauric Acid (L178550), a common saturated fatty acid found in nutmeg, palm kernel oil, coconut oil and butter fat.<br>References Liu, X. et al.: Int. J. Pharma., 443, 318 (2013);<br></p>Fórmula:C12D3H21O2Cor e Forma:White To Off-WhitePeso molecular:203.34Mosapride Citric Amide Disodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Disodium salt of Mosapride (M731000) derivative.<br>References Yoshida, N., et al.: Arch. Int. Pharmacodyn. Ther., 300, 51 (1989), Yatera, S., et al.: Japan. Pharmacol. Ther., 21, 21 (1993), Ruth, M., et al.: Aliment Pharmacol. Ther., 12, 35 (1998),<br></p>Fórmula:C27H29ClFN3Na2O9Cor e Forma:NeatPeso molecular:639.96epi Dienogest
Produto Controlado<p>Applications epi Dienogest, is metabolite of Dienogest (D441870), a derivative of 19-Nortestosterone, that in combination with estrogencan acts as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998),<br></p>Fórmula:C20H25NO2Cor e Forma:NeatPeso molecular:311.42Pinic Acid (Diastereomeric Mixture)
CAS:Produto Controlado<p>Applications Pinic Acid (Diastereomeric Mixture) can be used to prepare pinic acid diamides as herbicides.<br>References Zou,R., et al.: Guangxi Daxue Xuebao, Ziran Kexueban, 36, 463 (2011);<br></p>Fórmula:C9H14O4Cor e Forma:NeatPeso molecular:186.21Guanyl Urea Sulfate
CAS:<p>Applications It is used for detecting and determining Ni and its separation from Co and other metals.<br>References Jacob, K.D., et al.: J. Agric. Res., 28, 37 (1924),<br></p>Fórmula:C2H6N4O·H2O4SCor e Forma:NeatPeso molecular:302.272-O-Desmethyl Cisapride
CAS:Produto Controlado<p>Applications Minor Cisapride (C496400) metabolite.<br>References Meuldermans, W., et al.; Drug Metab. Disposition, 16, 410 (1988), Lowry J., et al.; Clin. pharmacol. ther., 73, 209 (2003), Shao L., et al.: Bioorg. Med. Chem. Lett., 19, 5679 (2009),<br></p>Fórmula:C22H27ClFN3O4Cor e Forma:NeatPeso molecular:451.924'-Bromo-2,2':6',2''-terpyridine
CAS:Produto Controlado<p>Applications 4'-Bromo-2,2':6',2''-terpyridine (cas# 149817-62-9) is a useful research chemical.<br></p>Fórmula:C15H10BrN3Cor e Forma:NeatPeso molecular:312.16Mianserin N-Oxide
CAS:Produto Controlado<p>Applications A metabolite of Mianserin.<br>References Begg, E., et al.: Br. J. Clin. Pharmacol., 27, 445 (1989), Tybring, G., et al.: Ther. Drug Monit., 17, 516 (1995), Namera, A., et al.: J. Anal. Toxicol. 22, 396 (1998), van Nederkassel, A., et al.: J. Pharm. Biomed. Anal., 32, 233 (2003),<br></p>Fórmula:C18H20N2OCor e Forma:NeatPeso molecular:280.364-Nitrophenol-1,2,6-13C3
CAS:Produto Controlado<p>Applications Labelled 4-Nitrophenol (N496945). Used in the manufacturing of pharmaceuticals, fungicides, dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C6H7NO3Cor e Forma:NeatPeso molecular:147.08(3R)-3-[4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinecarboxylic Acid Phenylmethyl Ester
CAS:Produto ControladoFórmula:C30H28N6O3Cor e Forma:NeatPeso molecular:520.582Diclofenac Carboxylic Acid (Diclofenac Metabolite)
CAS:Produto Controlado<p>Applications Metabolite of Diclofenac.<br>References Duffy, J.C., et al.: J. Pharm. Pharmacol., 48, 883 (1996), Oza, V., et al.: J. Med. Chem., 45, 321 (2002), Bajaj, S., et al.: Bioorg. Med. Chem., 12, 3695 (2004), Teffera, Y., et al.: Drug Metabolism Lett., 2, 35 (2008),<br></p>Fórmula:C13H9Cl2NO2Cor e Forma:Off-WhitePeso molecular:282.121,3-Dimethyl 2-[4-(methoxycarbonyl)-2-nitrophenyl]propanedioate
CAS:<p>Applications 1,3-Dimethyl 2-[4-(methoxycarbonyl)-2-nitrophenyl]propanedioate<br></p>Fórmula:C13H13NO8Cor e Forma:NeatPeso molecular:311.24(2-Nitrophenyl)hydrazine (Contains ~30-40% water as stabilizer)
CAS:<p>Applications (2-Nitrophenyl)hydrazine (cas# 3034-19-3) is a useful research chemical.<br></p>Fórmula:C6H7N3O2Cor e Forma:NeatPeso molecular:153.141,5-Dibromoanthracene
CAS:Produto Controlado<p>Applications 1,5-dibromoanthracene (cas# 3278-82-8) is a useful research chemical.<br></p>Fórmula:C14H8Br2Cor e Forma:NeatPeso molecular:336.02Azidoethanol
CAS:Produto Controlado<p>Applications 2-Azidoethanol is used as a reagent in the glycosylation of mono- or polysaccharides. 2-Azidoethanol is also used as a 2’-deoxy-ethynyluridine (EdU) blocker in nuclear DNA, preventing cross reactivity with other antibodies in order to better study its related pathways in the body.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Liboska, R., et al.: PLOS ONE, 7, e51679 (2012); Sun, X., et al.: Biomacromolecules, 3, 1065 (2002)<br></p>Fórmula:C2H5N3OCor e Forma:ColourlessPeso molecular:87.08(5-Chloro-2,1,3-benzothiadiazol-4-yl)-carbamimidothioic Acid Methyl Ester Hydriodide Salt
CAS:Produto Controlado<p>Applications Tizanidine (T449500) intermediate.<br></p>Fórmula:C8H8ClIN4S2Cor e Forma:NeatPeso molecular:386.66Betamethasone 21-Acetate 17-Propionate
CAS:<p>Impurity Betamethasone Dipropionate EP Impurity D<br>Applications Betamethasone 21-acetate-17-propionate (Betamethasone Dipropionate EP Impurity D) is a related compound of Betamethasone dipropionate (B327005).<br>References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Chen, B., et al.: Steriods, 74, 30 (2009), Mikami, E., et al.: J. Pharm. Biomed. Anal., 28, 261 (2002),<br></p>Fórmula:C27H35FO7Cor e Forma:NeatPeso molecular:490.561Conduritol A
CAS:Produto Controlado<p>Applications Conduritol A (cas# 526-87-4) is a compound useful in organic synthesis.<br></p>Fórmula:C6H10O4Cor e Forma:NeatPeso molecular:146.14Desphenyl Chloridazon-15N2
CAS:<p>Applications The labelled metabolite in soil and sugar beets of Chloridazon.<br>References Smith, D.T., et al.: Weed Sci., 18, 260 (1970),<br></p>Fórmula:C4H4Cl15N2NOCor e Forma:Off-WhitePeso molecular:147.531,3-Dimethylnaphthalene
CAS:Produto ControladoFórmula:C12H12Cor e Forma:ColourlessPeso molecular:156.223-(4'-Bromo[1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenol
CAS:Produto Controlado<p>Applications 3-(4'-Bromo[1,1'-biphenyl]-4-yl)-1,2,3,4-tetrahydro-1-naphthalenol is used to prepare 4-hydroxycoumarin derivatives with antitumor activities. It is also used to synthesize diphenacoum and brodifacoum (B677900) as the rodenticides.<br>References Jung, J., et al.: Bioorg. Med. Chem. Lett., 14, 5527 (2004); Van Heerden, P., et al.: J. Chem. Soc. Perkin Transactions 1: Organic and Bio-Organic Chemistry, 8, 1141 (1997)<br></p>Fórmula:C22H19BrOCor e Forma:NeatPeso molecular:379.29Pirenoxine
CAS:Produto Controlado<p>Applications Pirenoxine, is a medication used in the possible treatment and prevention of cataracts.<br>References Liao, J. H. et al.: Inorganic Chemistry. 50 (1): 365–377.<br></p>Fórmula:C16H8N2O5Cor e Forma:NeatPeso molecular:308.25(4-Bromophenyl)urea
CAS:<p>Applications (4-Bromophenyl)urea (cas# 1967-25-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C7H7N2OBrCor e Forma:Off-White To PurplePeso molecular:215.052-Hydroxy Atorvastatin Calcium Salt
CAS:Produto Controlado<p>Applications di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C66H68CaF2N4O12Cor e Forma:White To YellowPeso molecular:1187.35Succinylacetone
CAS:<p>Applications Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.<br>References Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991), Lindstedt, S., et al.: Lancet, 340, 813 (1992), Schulze, A., et al.: Clin. Chem., 47, 1424 (2001), Allard, P., et al.: Clin. Biochem., 37, 1010 (2004),<br></p>Fórmula:C7H10O4Cor e Forma:White To Off-WhitePeso molecular:158.1516α-Hydroxy Estrone
CAS:<p>Impurity Estriol EP Impurity H<br>Applications 16α-Hydroxy Estrone (Estriol EP Impurity H) is a major metabolite of Estradiol.<br>References Fishman, H.G, et al.: Biochemistry, 8, 4304 (1969), Ryan, Sugar, J., et al.: J. Clin. Endocrinol. Metab., 50, 137 (1980), Numazawa, M., et al.: Steroids, 38, 149 (1981), Travis, R., et al.: Breast Cancer Res., 5, 239 (2003),<br></p>Fórmula:C18H22O3Cor e Forma:White To BeigePeso molecular:286.37Xanthurenic Acid
CAS:<p>Applications Excreted by pyridoxine-deficient animals after the ingestion of tryptophan.<br>References Aquilina, J., et al.: Biochemistry, 39, 16176 (2000), Roberts, J., et al.: Photochem. Photobiol., 74, 740 (2001),<br></p>Fórmula:C10H7NO4Cor e Forma:NeatPeso molecular:205.17Dabigatran Carboxamide Ethyl Ester
CAS:<p>Applications Dabigatran Carboxamide Ethyl Ester is an impurity of Dabigatran Etexilate Mesylate (D100150) which is a nonpeptide, direct thrombin inhibitor.<br>References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002); Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002); Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005)<br></p>Fórmula:C27H28N6O4Cor e Forma:Off-WhitePeso molecular:500.55Adenosine 5'-Monophosphate
CAS:Produto Controlado<p>Applications Adenosine 5'-Monophosphate is a natural occurring nucleotide and a useful ligand determinant that facilitate the binding of APS reductase inhibitors and activates adenosine receptor agonists.<br>References Hong, J.A. et al.: J. Med. Chem., 52, 5485 (2009); Korboukh I. et al.: J. Med. Chem., 55, 6467 (2012)<br></p>Fórmula:C10H14N5O7PCor e Forma:NeatPeso molecular:347.224-Hydroxy Estradiol 1-N7-Guanine
CAS:Produto Controlado<p>Applications 4-Hydroxy Estradiol 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H27N5O4Cor e Forma:NeatPeso molecular:437.49Hederagenin
CAS:<p>Applications Triterpenoid which can inhibit the proliferation of leukemia HL-60 cells.<br>References Cho, J., et al.: Pulmon. Pharmacol. Ther., 23, 190 (2010), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Saha, S., et al.: J. Agric. Food Chem., 58, 434 (2010),<br></p>Fórmula:C30H48O4Cor e Forma:NeatPeso molecular:472.70N-(Methyl-d3)-4-phenylpyridinium Iodide
CAS:Produto Controlado<p>Applications A labelled dopaminergic neurotoxin; a selective cytostatic agent in small-cell lung cancer cell lines with neuroendocrine properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Marini, A.M. et al.: J, Nat. Cancer Inst., 84, 1582 (1992); Singh, M. et al.: Arch. Biochem. Biophys., 286, 138 (1991); Santiago, M. et al.: J. Neurosci. Meth., 108, 181 (2001);<br></p>Fórmula:C122H3H9N·ICor e Forma:NeatPeso molecular:300.15(4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
CAS:Produto Controlado<p>Impurity Rosuvastatin EP Impurity F<br>Applications (4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester (Rosuvastatin EP Impurity F) is a Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.<br>References Beck, et al.: J. Med. Chem., 33, 52 (1999),<br></p>Fórmula:C29H40FN3O6SCor e Forma:NeatPeso molecular:577.71α-Hydroxy Metoprolol (Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications A metabolite of Metoprolol.<br>References Lennard, M.S., et al.: Br. J. Clin. Pharmacol., 14, 713 (1982), Gengo, F.M., et al.: Clin. Pharmacol. Ther., 36, 320 (1984),<br></p>Fórmula:C15H25NO4Cor e Forma:Off-White To BeigePeso molecular:283.363-Ethyl Adenine-d5 (2% d0)
CAS:Produto Controlado<p>Applications 3-Ethyl Adenine-d5 (2% d0) (cas# 147028-85-1) is a compound useful in organic synthesis.<br></p>Fórmula:C72H5H4N5Cor e Forma:White To Off-WhitePeso molecular:168.21Hydroxocobalamin Acetate
CAS:Produto Controlado<p>Applications Physiological analog of vitamin B12 where the CN group is replaced with OH. Exists in aqueous solution as an equilibrium mixture of the hydroxy isomer and the ionic aqua isomer (aquacobalamin). Precursor of the coenzymes methylcobalamin and cobamamide. Coordination Compound. Vitamin (hematopoietic).<br>References Kaczka, E.A., et al.: Science, 112, 354 (1950), Friedrich, W., et al.: Vitamins, 837 (1988), Forsyth, J.C., et al.: Clin. Toxicol., 31, 277 (1993),<br></p>Fórmula:C64H91CoN13O16PCor e Forma:Dark RedPeso molecular:1388.39Hydrocinnamic Acid-1,2,3-13C3
CAS:Produto Controlado<p>Applications Labelled analogue of Hydrocinnamic Acid, a cinnamic acid derivative used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.<br>References Migliaccio, A., et al.: Blood, 76, 1150 (1990); McDonagh, K., et al.: J. Biol. Chem., 266, 11965 (1991);<br></p>Fórmula:C613C3H10O2Cor e Forma:NeatPeso molecular:150.175-Methyl Cytosine-13C,15N2 Hydrochloride
CAS:<p>Applications A labelled derivative of Dibarbituric acid.<br>References Hitchings, G.H., et al.: J. Biol. Chem., 177, 357 (1949),<br></p>Fórmula:CC4H715N2NO·ClHCor e Forma:NeatPeso molecular:164.572-Nitrophenol-3,4,5,6-d4
CAS:Produto Controlado<p>Applications 2-Nitrophenol-3,4,5,6-d4 (CAS# 93951-78-1) is a useful isotopically labeled research compound.<br></p>Fórmula:C6D4HNO3Cor e Forma:NeatPeso molecular:143.13cis-10-Hydroxy Nortriptyline
CAS:<p>Applications A metabolite of Nortriptyline (N837000).<br>References Callaghan, R., et al.: J. Biol. Chem., 268, 16059 (1993), Dagenais, C., et al.: Biochem. Pharmacol., 67, 269 (2004), Doran, A., et al.: Drug Metab. Dispos., 33, 165 (2005),<br></p>Fórmula:C19H21NOCor e Forma:NeatPeso molecular:279.38Juvenile Hormone B 3 (Mixture of Diastereomers), Technical Grade
CAS:Produto Controlado<p>Applications Juvenile Hormone B 3 is a sesquiterpenoid produced by the larval ring gland and adult corpus allatum (CA) of Drosophila melanogaster. Juvenile hormones regulate development, reproduction, diapause, and polyphenisms.<br>References Wang, Ch., et al.: Gen. Comp. Endocr., 176, 347 (2012); Bendena, W.G., et al.: Gen. Comp. Endocr., 172, 56 (2011); Wyatt, G., Davey, K.: Adv. Insect Physiol., 26, 1 (1996); Nijhout, H.: Insect Hormones (Princeton Univ. Press, Princeton) (1994)<br></p>Fórmula:C16H26O4Cor e Forma:NeatPeso molecular:282.38Digoxigenin Bisdigitoxoside
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Fórmula:C35H54O11Cor e Forma:NeatPeso molecular:650.80L-Methionine Sulfoxide,13C
CAS:Produto Controlado<p>Applications L-Methionine Sulfoxide 13C1 is a labelled analogue of L-Methionine Sulfoxide ( M260450). L-Methionine Sulfoxide ( M260450) an intermediate in the synthesis of the acyclic amino carboxylic acid L-Methionine sulfoximine.<br>References Lee, B., et al.: J. Biol. Chem., 283, 28361 (2008), Nordqvist, A., et al.: Bioorg. Med. Chem., 16, 5501 (2008);Balog, E., et al.: Biochem., 48, 3005 (2009);<br></p>Fórmula:CC4H11NO3SCor e Forma:White To Off-WhitePeso molecular:166.2034-Hydroxy Omeprazole Sulfide
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications An intermediate in the preparation of Omeprazole metabolites.<br>References Hoffmann, K., et al.: Drug Metab. Disposition, 14, 341 (1986), Andersson, T., et al.: Brit. J. Clin. Pharmacol., 36, 521 (1993),<br></p>Fórmula:C16H17N3O2SCor e Forma:NeatPeso molecular:315.39rac Indapamide-N-sulfonamido-β-D-glucuronide (Mixture of Diastereomers)
<p>Stability Hygroscopic<br>Applications rac Indapamide-N-sulfonamido-β-D-glucuronide_x000D__x000D_(Mixture of Diastereomers) is a compound useful in organic synthesis.<br></p>Fórmula:C22H24ClN3O9SPureza:>85%Cor e Forma:Off White SolidPeso molecular:541.96Benfotiamine-Amide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Benfotiamine-Amide is an analog of Benfotiamine, which is a Vitamin B1 analog. Synthetic S-acyl derivative of Thiamine (T344185).<br>References Stracke, H., et al.: Exper. Clin. Endocrinol., Diabetes, 116, 600 (2008), Gohil, V., et al.: Nat., Biotechnol., 28, 249 (2010),<br></p>Fórmula:C26H27N4O7PSCor e Forma:NeatPeso molecular:570.55p-Salicylic Acid 4-Sulfate Disodium Salt
CAS:Produto Controlado<p>Applications p-Salicylic Acid 4-Sulfate is a urine metabolite of Methylated paraben (B693600), an antimicrobial agent used in cosmetic products.<br>References Tsukamoto, H., et al: Chem. Pharma. Bull., 10, 86 (1962); Desai, N.B., et al.: J. Sci. Indust. Res., 14, 330 (1955);<br></p>Fórmula:C7H4O6S·2NaCor e Forma:NeatPeso molecular:262.151,2-Benzenedicarboxylic Acid, mixed decyl and hexyl and octyl diesters (1:1:1 Mixture of B185420 and
CAS:Produto Controlado<p>Applications 1,2-Benzenedicarboxylic Acid, mixed decyl and hexyl and octyl diesters_x000D_(1:1:1 Mixture of B185420 and D228455 and D228460) (cas# 68648-93-1) is a compound useful in organic synthesis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C11H9D3O4Cor e Forma:ColourlessPeso molecular:390.556Acetyltropic Acid
CAS:Produto Controlado<p>Applications Intermediate in the synthesis of Tropine and respective derivatives<br>References Schmidt, G., et al.: J. Pharm. Sci., 56, 215 (1967),<br></p>Fórmula:C11H12O4Cor e Forma:NeatPeso molecular:208.21Indole-3-butyric Acid
CAS:<p>Applications Used to stimulate root formation of plant clippings. Suitable for plant cell culture tested.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Handa, A., et al.: Plant Physiol., 69, 514 (1982), Polanco, C., et al.: Plant Sci., 162, 817 (2002), Rzepka-Plevnes, D., et al.: J. Food Agric. Environ., 5, 194 (2007),<br></p>Fórmula:C12H13NO2Cor e Forma:BeigePeso molecular:203.243-(4-Chlorophenyl)glutaric Acid
CAS:<p>Applications 3-(4-Chlorophenyl)glutaric Acid (cas# 35271-74-0) is a compound useful in organic synthesis. Baclofen Impurity 1<br></p>Fórmula:C11H11ClO4Cor e Forma:NeatPeso molecular:242.66Tenofovir Alafenamide-d5 Fumarate(diastereomers)
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications Tenofovir Alafenamide-d5 Fumarate (diastereomers), is labeled GS 7171. Tenofovir Alafenamide (T018555) is an isomer of GS 7171.<br></p>Fórmula:C21H24D5N6O5P·C4H4O4Cor e Forma:NeatPeso molecular:481.5011607Kitol Diacetate (Mixture of Diastereomers)
CAS:Fórmula:C44H64O4Cor e Forma:NeatPeso molecular:656.9766Finasteride 2-(2-Methylpropanol)amide
CAS:Produto ControladoFórmula:C23H36N2O3Cor e Forma:NeatPeso molecular:388.54Isovaleryl L-Carnitine-d3 Chloride
CAS:Produto Controlado<p>Applications Isovaleryl L-Carnitine-d3 Chloride is labelled Isovaleryl L-Carnitine Chloride (I917580) which is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.<br>References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)<br></p>Fórmula:C12D3H21NO4·ClCor e Forma:NeatPeso molecular:284.7954-Hydroxy Atorvastatin Hemicalcium Salt
CAS:<p>Applications 4-Hydroxyatorvastatin is a hydroxylated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S. et al.: Am. J. Cardiol., 80, 10H (1997); Jacobsen, W. et al.: Drug Metab. Dispos., 28, 1369 (2000); Istvan, E. et al.: Science, 292, 1160 (2001); Tabernero, L. et al.: J. Biol. Chem., 278, 19933 (2003); Bratton, L. et al.: Bioorg. Med. Chem., 15, 5576 (2007);<br></p>Fórmula:C66H68CaF2N4O12Pureza:>90%Cor e Forma:NeatPeso molecular:1187.34Caffeic Acid-13C3
CAS:<p>Applications Constituent of plants, probably occurs in plants only in conjugated forms.<br>References Neish, et al.: Can. J. Biochem Physiol., 37, 1431 (1959), Krasemann, et al.: Arch. Pharm., et al.: 293, 721 (1960), Wolfrom, et al.: J. Agric. Food Chem., 8, 58 (1960),<br></p>Fórmula:C613C3H8O4Cor e Forma:NeatPeso molecular:183.14Anthracene
CAS:<p>Applications Anthracene is obtained from coal tar. It is an important source of many dyes.This compound is a contaminant of emerging concern (CECs)<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C14H10Cor e Forma:Light Yellow To Light BrownPeso molecular:178.23Propoxyphenyl-thiohydroxyhomosildenafil
CAS:Produto Controlado<p>Applications Propoxyphenyl-thiohydroxyhomosildenafil is an analogue of Hydroxythiohomo Sildenafil (H963150).<br>References Balayssac, S., et. al.: J. Pharmaceut. Biomed., 63, 135 (2012)<br></p>Fórmula:C24H34N6O4S2Cor e Forma:NeatPeso molecular:534.69N-1-Naphthylethylenediamine Dihydrochloride
CAS:<p>Stability Air Sensitive, Hygroscopic<br>Applications N-1-Naphthylethylenediamine Dihydrochloride, is an organic building block used for the chemical synthesis. It can also be used as highly selective organic fluorescent probe for azide ion.<br>References Sahana, A., et al.: Analyst , 137, 1544 (2012);<br></p>Fórmula:C12H16Cl2N2Cor e Forma:NeatPeso molecular:186.2523646Linagliptin
CAS:<p>Applications Linagliptin is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.<br>References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);<br></p>Fórmula:C25H28N8O2Cor e Forma:White To OrangePeso molecular:472.54
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