Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(274.687 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.776 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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Dimefline Hydrochloride
CAS:Produto Controlado<p>Applications Dimefline is a new respiratory stimulant drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Edwards, J.M., et al.: J. Nat. Prod., 42, 85 (1979), Setnikar, I., et al.: Arzneim.-Forsch., 11 1109 (1961),<br></p>Fórmula:C20H21NO3·HClCor e Forma:NeatPeso molecular:359.852-Isopropylnaphthalene
CAS:Produto Controlado<p>Applications 2-Isopropylnaphthalene has been seen to likely act as CYP2F2 substrates through molecular modelling of the mouse cytochrome P450 CYP2F2.<br>References Lewis, D.F.V., et. al.: Drug Metab. and Drug Interact., 19, 97 (2002)<br></p>Fórmula:C13H14Cor e Forma:NeatPeso molecular:170.25Epitizide
CAS:Produto Controlado<p>Applications Epitizide is a diuretic agent.<br>References Pilsbury, V., et al.: J. Pharm. Pharmacol., 18, 713 (1966), Tisdall, P., et al.: Clin. Chem., 26, 702 (1980),<br></p>Fórmula:C10H11ClF3N3O4S3Cor e Forma:White To Off-WhitePeso molecular:425.86Atorvastatin Methyl Ester
CAS:Produto Controlado<p>Applications Atorvastatin impurity. Atorvastatin Methyl Ester<br>References Graul, A., et al.: Drugs Future, 22, 956 (1997),<br></p>Fórmula:C34H37FN2O5Cor e Forma:White To Off-WhitePeso molecular:572.67S 23
CAS:<p>Applications S 23 is a selective androgen receptor modulator.<br>References Thevis, M., et al.: Drug Testing and Analysis, 2, 589 (2010); Jones, A., et al.; Endocr., 150, 385 (2009)<br></p>Fórmula:C18H13ClF4N2O3Cor e Forma:White To Off-WhitePeso molecular:416.75δ-Valerolactam-d4
CAS:Produto Controlado<p>Applications δ-Valerolactam-d4 is a labeled analog of δ-Valerolactam (V091440), which is a useful synthetic intermediate. It is an intermediate used to synthesize Cenicriviroc (C256550), an experimental drug candidate for the treatment of HIV infection. It is also a starting material for a new route to hexahydrojulolidines, using intramolecular 1,4-cycloaddition.<br>References Potts, K., et al. J. Org. Chem., 58, 5040 (1993); Klibanov, O., et al.: Curr. Opinion Invest. Drugs, 11, 940 (2010);<br></p>Fórmula:C5H5D4NOCor e Forma:NeatPeso molecular:103.16(2R,3S)-4-(2-Quinoxalinyl)-1,2,3-butanetriol
CAS:Produto Controlado<p>Applications A food metabolite.<br></p>Fórmula:C12H14N2O3Cor e Forma:Off-White To BeigePeso molecular:234.25α,2,4-Trichloroacetophenone
CAS:Produto Controlado<p>Applications α,2,4-Trichloroacetophenone is a reagent used in the synthesis of isoconazole, a potent antifungal agent.<br>References Dulcevscaia, G. et al.: Polyhed., 52, 106 (2013); Wang, Y. et al.: Bioorg. Med. Chem. Lett., 22, 5363 (2012);<br></p>Fórmula:C8H5Cl3OCor e Forma:NeatPeso molecular:223.482,7-Diisopropylnaphthalene
CAS:Produto Controlado<p>Applications 2,7-Diisopropylnaphthalene (cas# 40458-98-8) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C16H20Cor e Forma:ColourlessPeso molecular:212.331-Naphthol
CAS:<p>Impurity Duloxetine EP Impurity D<br>Applications 1-Naphthol (Duloxetine EP Impurity D) is used in the manufacturing of dyes, intermediates, synthetic perfumes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C10H8OCor e Forma:Light Red To Light BrownPeso molecular:144.172,3,5-Tri-O-benzyl-D-ribono-1,4-lactone
CAS:Produto Controlado<p>Applications 2,3,5-Tri-O-benzyl-D-ribono-1,4-lactone (cas# 55094-52-5) is a useful research chemical.<br></p>Fórmula:C26H26O5Cor e Forma:NeatPeso molecular:418.4822'-Hydroxyflavone
CAS:Produto Controlado<p>Applications 2'-Hydroxyflavone (cas# 35244-11-2) is a useful research chemical.<br></p>Fórmula:C15H10O3Cor e Forma:NeatPeso molecular:238.238Citric acid-2,4-13C2
CAS:Produto Controlado<p>Applications Citric acid-2,4-13C2 is an isotopic analog of citric acid (C521000), a component of the Krebs cycle.<br></p>Fórmula:C2C4H8O7Cor e Forma:White To Light YellowPeso molecular:194.11β-Geranyl Acetate
CAS:<p>Applications β-Geranyl Acetate is found in essential oils such as Moroccan commercial essential oils which has anti-oxidant, anti-inflammatory and anti-proliferative activities; and in Salvia scabiosifolia from Bulgaria.<br>References Aazza, S., et. al.: Nat. Prod. Comm., 9, 587 (2014); Marchev, A., et. al.: J. Essential Oil-bearing Plants, 15, 908 (2012)<br></p>Fórmula:C12H20O2Cor e Forma:NeatPeso molecular:196.29Aldosterone 3-(O-Carboxymethyl)oxime (>80%)
CAS:Produto ControladoFórmula:C23H31NO7Cor e Forma:NeatPeso molecular:433.491-[3-(Dimethylamino)propyl]-3-ethylurea
CAS:Produto Controlado<p>Applications 1-[3-(Dimethylamino)propyl]-3-ethylurea is a reagent used in the preparation of water soluble, multifunctional antibody-porphyrin gold nanoparticles.<br>References Penon, O. et al.: J. Colloid. Inter. Sci., 496, 100 (2017);<br></p>Fórmula:C8H19N3OCor e Forma:NeatPeso molecular:173.26O-Desmethyl Astemizole
CAS:Produto Controlado<p>Applications A metabolite of Astemizole.<br>References Nagata, K., et al.: J. Biol. Chem., 268, 24720 (1993), Benton, R., et al.: Clin. Pharmacol. Ther., 59, 383 (1996), Hashizume, T., et al.: Drug Metab. Dispos., 26, 566 (1998), Scarborough, P., et al.: Drug Metab. Rev., 31, 205 (1999),<br></p>Fórmula:C27H29FN4O·ClHCor e Forma:NeatPeso molecular:481.00Benzyl Cinnamate
CAS:<p>Applications BENZYL CINNAMATE (cas# 103-41-3) is a useful research chemical.<br></p>Fórmula:C16H14O2Cor e Forma:WhitePeso molecular:238.28Robinetin
CAS:Produto Controlado<p>Applications Robinetin (cas# 490-31-3) is a useful research chemical.<br></p>Fórmula:C15H10O7Cor e Forma:NeatPeso molecular:302.243-Iodothyroacetic Acid
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3-Iodothyronacetic Acid is a 3-Iodothyronamine metabolite that has functional effects in FRTL-5 thyroid cells.<br>References Agretti, P. et al.: J. Mol. Endocrinol., 47, 23 (2011);<br></p>Fórmula:C14H11IO4Cor e Forma:NeatPeso molecular:370.139Cholesterol-d6
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled Cholesterol (C432501). Cholesterol is the principal sterol of the higher animals. Cholesterol was found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Cholesterol is the main constituent of gallstones.<br>References Rosin, Z., et al.: Physiol. Chem., 124, 282 (1923), Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934), Gemant, et al.: Life Sci., 1, 233 (1962), Johnson, K., et al.: 4, 457 (1964),<br></p>Fórmula:C272H6H40OCor e Forma:Off White SolidPeso molecular:392.69all-trans 5,6-Epoxy Retinoic Acid
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications A metabolite of all-trans Retinoic acid (R250200).<br>References Idres, N., et al.: Cancer Res., 61, 700 (2001), Taimi, M., et al.: J. Biol. Chem., 279, 77 (2004), Vermot, J., et al.: Science, 308, 563 (2005),<br></p>Fórmula:C20H28O3Cor e Forma:Light YellowPeso molecular:316.43(1S)-(+)-10-Camphorsulfonic Acid
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Used as a resolving agent, and as a catalyst for coupling dipeptides.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C10H16O4SCor e Forma:NeatPeso molecular:232.30trans-Caffeic Acid
CAS:<p>Applications trans-Caffeic Acid is a useful synthetic intermediate. It was used as a reactant to synthesize N-caffeoylphenalkylamide derivatives as bacterial efflux pump inhibitors. It is also used to prepare caffeic acid phenethyl ester analogs with antitumor structures.<br>References Michalet, S., et al.: Bioorg. Med. Chem. Lett., 17, 1755 (2007); Nagaoka, T., et al.: Bioorg. Med. Chem., 10, 3351 (2002)<br></p>Fórmula:C9H8O4Cor e Forma:NeatPeso molecular:180.16Tetramethyluric Acid
CAS:Produto Controlado<p>Applications Tetramethyluric acid is an impurity of caffeine. Caffeine is a bitter, white crystalline xanthine alkaloid that acts as a stimulant drug and a reversible acetylcholinesterase inhibitor. Caffeine is found in varying quantities in the seeds, leaves, and fruit of some plants, where it acts as a natural pesticide that paralyzes and kills certain insects feeding on the plants. In humans, caffeine acts as a central nervous system stimulant, temporarily warding off drowsiness and restoring alertness. Caffeine is a cardiac and respiratory stimulant; diuretic. Caffeine is toxic at sufficiently high doses.<br>References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988);<br></p>Fórmula:C9H12N4O3Cor e Forma:NeatPeso molecular:224.222,6-Dichlorophenylacetic Acid Methyl Ester
CAS:Produto Controlado<p>Applications Intermediate in the preparation of Guanfacine<br></p>Fórmula:C9H8Cl2O2Cor e Forma:NeatPeso molecular:219.06Cresyl Diphenyl Phosphate-d7 Isomer 1
CAS:Produto Controlado<p>Applications Cresyl Diphenyl Phosphate-d7 Isomer 1 is the deuterated form of Cresyl Diphenyl Phosphate (C783015), which is a phosphorus flame retardant additive.<br>References van der Veen., et al.: Chemosphere, 88, 1119 (2012);<br></p>Fórmula:C19D7H10O4PCor e Forma:NeatPeso molecular:347.3532,2',3,4,4',5'-Hexabromodiphenyl Ether
CAS:Produto Controlado<p>Applications 2,2',3,4,4',5'-Hexabromodiphenyl Ether is a polybrominated diphenyl ether (PBDE) used as a flame retardant.<br>References Rayne, S., et al.: Environ. Int., 32, 575 (2006); Jakobsson, K., et al.: Chemosphere, 46, 709 (2002)<br></p>Fórmula:C12H4Br6OCor e Forma:White To Off-WhitePeso molecular:643.582'-Chloroacetophenone
CAS:Produto Controlado<p>Applications 2'-Chloroacetophenone (cas# 2142-68-9) is a compound useful in organic synthesis.<br></p>Fórmula:C8H7ClOCor e Forma:NeatPeso molecular:154.592-Hydroxycinnamic Acid
CAS:Produto Controlado<p>Applications 2-Hydroxycinnamic Acid (cas# 614-60-8) is a useful research chemical.<br></p>Fórmula:C9H8O3Cor e Forma:NeatPeso molecular:164.165-Iodovanillic Acid
CAS:Produto Controlado<p>Applications 5-Iodovanillic acid (cas# 98554-57-5) is a useful research chemical.<br></p>Fórmula:C8H7IO4Cor e Forma:Off-WhitePeso molecular:294.04Inosine-5'-monophosphate Disodium Salt Hydrate
CAS:Produto Controlado<p>Applications Inosine-5'-monophosphate Disodium Salt Hydrate is used in Raman spectra of alkali and alkaline earth metal salts of inosine 5'-monophosphoric acid.<br>References Carmona, P., et al.: J. Raman Spectrosc., 27, 817 (1996)<br></p>Fórmula:C10H11N4O8PNa·xH2OCor e Forma:NeatPeso molecular:392.17+144.12(-)-trans-Verbenol
CAS:Produto Controlado<p>Applications (-)-trans-Verbenol is obtained in essential oil extracted from leaves of Teucrium capitatum L.It exhibits antimicrobial properties<br>References El Amri, J., et al.: Asian J. Pharm. Clinical Res., 10, 112 (2017)<br></p>Fórmula:C10H16OCor e Forma:NeatPeso molecular:152.233Atorvastatin Lactam Sodium Salt Impurity
CAS:<p>Impurity Atorvastatin Pyrrolidone Analog (USP)<br>Stability Light Sensitive<br>Applications A photodegradation product of Atorvastatin (a cyclic impurity of Atorvastatin). Atorvastatin Pyrrolidone Analog (USP).<br>References Roger, D., et al.: Clin. Exp. Dermatol., 19, 88 (1994), Cosa, G., et al.: Photochem. Photobiol., 80, 159 (2004), Kerwin, B., et al.: J. Pharm. Sci., 96, 1468 (2007),<br></p>Fórmula:C33H34FN2O6·NaCor e Forma:WhitePeso molecular:596.62Mosapride Citric Amide Disodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Disodium salt of Mosapride (M731000) derivative.<br>References Yoshida, N., et al.: Arch. Int. Pharmacodyn. Ther., 300, 51 (1989), Yatera, S., et al.: Japan. Pharmacol. Ther., 21, 21 (1993), Ruth, M., et al.: Aliment Pharmacol. Ther., 12, 35 (1998),<br></p>Fórmula:C27H29ClFN3Na2O9Cor e Forma:NeatPeso molecular:639.96Isovaleryl L-Carnitine Chloride
CAS:Produto Controlado<p>Applications Isovaleryl L-Carnitine Chloride is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.<br>References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)<br></p>Fórmula:C12H24ClNO4Cor e Forma:NeatPeso molecular:281.783,5-Diamino-6-chloropyrazine-2-carboxylic Acid Methyl Ester
CAS:Produto ControladoFórmula:C6H7ClN4O2Cor e Forma:NeatPeso molecular:202.604-(4-Oxobutyl)benzoic Acid Methyl Ester
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-(4-Oxobutyl)benzoic Acid Methyl Ester is used as a reagent in the preparation of Pemetrexed (P219500) and furoxanoxyalkyl esters of Pemetrexed as antifolates and nitric oxide donors for use as anticancer agents.<br>References Zhao, D., et al.: Zhongguo Yaowu Huaxue Zazhi, 18, 445 (2008); Yi, B., et al.: Zhongguo Yiyao Gongye Zazhi, 37, 798 (2006); Min, T., et al.: Med. Chem. Res., 18, 495 (2009)<br></p>Fórmula:C12H14O3Cor e Forma:NeatPeso molecular:206.24Naphthalene-2-sulfonic Acid Hydrate
CAS:<p>Applications Naphthalene-2-sulfonic acid (cas# 120-18-3) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C10H8O3SCor e Forma:NeatPeso molecular:208.234Potassium p-Nitrophenyl Sulphate
CAS:<p>Applications Potassium p-Nitrophenyl Sulphate (cas# 6217-68-1) is a compound useful in organic synthesis.<br></p>Fórmula:C6H4NO6S·KCor e Forma:NeatPeso molecular:257.269-(N-Methylaminomethyl)anthracene
CAS:Produto Controlado<p>Applications 9-(N-Methylaminomethyl)anthracene is a reactant that has been used in the synthesis of anthracene-oxyquinoline dyad as a fluorescent indicator for Hg(II).<br>References Praveen, L., et. al.: Tetrahedron Lett., 53, 3951 (2012)<br></p>Fórmula:C16H15NCor e Forma:NeatPeso molecular:221.3N-Acetyl Desethyl Chloroquine-d4
CAS:Produto Controlado<p>Applications A labelled Chloroquine metabolite, also an intermediate in the preparation of labelled Chloroquine It is a COVID19-related research product.<br>References Brown, N., et al.: J. Chromatogr., Biomed. App., 309, 426 (1984), Nord, K., et al.: Int. J. Pharm., 72, 11 (1991),<br></p>Fórmula:C18D4H20ClN3OCor e Forma:NeatPeso molecular:337.883-(4-Hydroxyphenyl)propionic Acid Methyl Ester
CAS:Produto Controlado<p>Applications 3-(4-Hydroxyphenyl)propionic Acid Methyl Ester is a useful synthetic intermediate. It can be used to prepare potent and orally available G protein-coupled receptor 40 agonists as potential antidiabetic agents.<br>References Sasaki, S., et al.: J. Med. Chem., 54, 1365 (2011); Christiansen, E., et al.: ACS Med. Chem. Lett., 1, 345 (2010)<br></p>Fórmula:C10H12O3Cor e Forma:NeatPeso molecular:180.2Hydroxy Urea-13C,15N2
CAS:Produto Controlado<p>Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Fórmula:CH4N2O2Cor e Forma:Off White SolidPeso molecular:79.033-(3-Amino-4-methylphenyl)-5-isopropylimidazolidine-2,4-dione
Produto ControladoFórmula:C13H17N3O2Cor e Forma:NeatPeso molecular:247.3epi Dienogest
Produto Controlado<p>Applications epi Dienogest, is metabolite of Dienogest (D441870), a derivative of 19-Nortestosterone, that in combination with estrogencan acts as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998),<br></p>Fórmula:C20H25NO2Cor e Forma:NeatPeso molecular:311.424’-Chloro-2-hydroxy-benzophenone
CAS:Produto Controlado<p>Applications 4’-Chloro-2-hydroxy-benzophenone is a useful compound to investigate the effects of substituents on photo-antioxidant abilities of 2-hydroxybenzoyl compounds that can prevent autooxidation of plastics under UV light.4’-Chloro-2-hydroxy-benzophenone can also utilized to develop novel Azomethine Prodrugs of (R)-α-Methylhistamine.<br>References Dobashi, Y., et al.: Polym. Degrad. Stabil. 89, 140 (2005); Krause, M., et al.: J. Med. Chem. 38, 4070 (1995)<br></p>Fórmula:C13H9ClO2Cor e Forma:NeatPeso molecular:232.66Trimethylurea
CAS:Produto Controlado<p>Applications Trimethylurea (cas# 632-14-4) is a useful research chemical.<br></p>Fórmula:C4H10N2OCor e Forma:NeatPeso molecular:102.142-Aminoanthracene
CAS:Produto Controlado<p>Stability Air Sensitive<br>Applications 2-AMINOANTHRACENE (cas# 613-13-8) is a useful research chemical.<br></p>Fórmula:C14H11NCor e Forma:NeatPeso molecular:193.24
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