Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.774 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.613 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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(S)-(-)-Carvedilol
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications The optically active isomer of Carvedilol (C184625), a nonselective ß-adrenergic blocker with a1-blocking activity. An antihypertensive used in the treatment of congestive heart failure.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990),<br></p>Fórmula:C24H26N2O4Cor e Forma:Off White SolidPeso molecular:406.4721-Desacetyl Amcinonide
CAS:Produto Controlado<p>Applications Amcinonide (A576150) analog as glucocorticoid receptor agonists for the treatment of inflammation and allergic conditions.<br>References Woodford, R., et al.: Curr. Ther. Res., 26, 301 (1979),<br></p>Fórmula:C26H33FO6Cor e Forma:NeatPeso molecular:460.544-Hydroxy-2-oxovaleric Acid Potassium Salt (>90%)
CAS:Produto Controlado<p>Applications 4-Hydroxy-2-oxovaleric acid potassium salt is converted from pyrocatechol metabolism by Pseudomonas.<br>References Dagley, S., et al.: J. Biol. Chem., 239, PC1284 (1964);<br></p>Fórmula:C5H7KO4Pureza:>90%Cor e Forma:NeatPeso molecular:170.205Cabazitaxel
Produto Controlado<p>Applications A novel semi-synthetic taxane with antitumor activity used for the treatment of castration-resistant prostate cancer. A microtubule inhibitor.<br>References Agarwal, N. et al.: Fut. Oncol., 7, 15 (2011); Mita, A. et al.: Clin. Cancer Res., 15, 723 (2009); Figg, W.D. et al.: Cancer Biol. Ther., 10, 1233 (2010);<br></p>Fórmula:C45H57NO14Cor e Forma:White SolidPeso molecular:835.936β-Hydroxy-21-desacetyl Deflazacort
CAS:<p>Applications The major metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Fórmula:C23H29NO6Cor e Forma:NeatPeso molecular:415.48Digoxigenin Monodigitoxoside
CAS:Produto Controlado<p>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Fórmula:C29H44O8Cor e Forma:BeigePeso molecular:520.65Acetyltropic Acid
CAS:Produto Controlado<p>Applications Intermediate in the synthesis of Tropine and respective derivatives<br>References Schmidt, G., et al.: J. Pharm. Sci., 56, 215 (1967),<br></p>Fórmula:C11H12O4Cor e Forma:NeatPeso molecular:208.212-Fluoroadenosine
CAS:Produto Controlado<p>Applications 2-Fluoroadenosine is a fluorinated analog of Adenoside (A280400) nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010);<br></p>Fórmula:C10H12FN5O4Cor e Forma:NeatPeso molecular:285.231-Naphthoic Acid-d7
CAS:Produto Controlado<p>Applications 1-Naphthoic Acid-d7 (cas# 634179-80-9) is a compound useful in organic synthesis.<br></p>Fórmula:C112H7HO2Cor e Forma:NeatPeso molecular:179.224-Amino-1-naphthalenesulfonic Acid
CAS:<p>Applications 4-Amino-1-naphthalenesulfonic acid has potent therapeutic applications. Its sodium salt has been used as non-toxic hemostatic. It is also a metabolite of azo dyes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Alonso, M., et al.: Anal. Chim. Acta, 400, 211 (1999); Chung, K., et al.: Appl. Environ. Microb., 42, 641 (1981)<br></p>Fórmula:C10H9NO3SCor e Forma:NeatPeso molecular:223.253-(3-Amino-4-methylphenyl)-5-isopropylimidazolidine-2,4-dione
Produto ControladoFórmula:C13H17N3O2Cor e Forma:NeatPeso molecular:247.36-Hydroxy Bromantane
CAS:Produto Controlado<p>Applications 6-Hydroxy Bromantane is a metabolite of Bromantane (B678450).<br>References Bi, H., et al.: J. Steroid Biochem. Mol. Biol., 42, 229 (1992), Pozo, O., et al.: Anal. Bioanal. Chem., 389, 1209 (2007), Kiousi, P., et al.: Bioanalysis, 1, 1209 (2009),<br></p>Fórmula:C16H20BrNOCor e Forma:NeatPeso molecular:322.241,4-Dibromonaphthalene
CAS:Produto Controlado<p>Applications 1,4-Dibromonaphthalene is used in the annelation of PAHs. Also used in the synthesis of novel, orally active dual NK1/NK2 antagonists.<br>References Bernstein, P. et al.: Bioorg. Med. Chem. Lett., 11, 2769 (2001); Wegner, H. et al.: J. Org. Chem., 68, 883 (2003);<br></p>Fórmula:C10H6Br2Cor e Forma:NeatPeso molecular:285.963'-Azido-3'-deoxythymidine-methyl-d3 β-D-glucuronide, Sodium Salt
CAS:Produto Controlado<p>Applications A deuterated metabolite of the potent and selective inhibitor of HIV-1 replication, AZT.This compounds contains Sodium Chloride. Water content not determined.<br></p>Fórmula:C16D3H17N5O10·NaCor e Forma:NeatPeso molecular:468.3658Diclofenac Acyl-β-D-glucuronide Allyl Ester
CAS:Produto Controlado<p>Applications An intermediate for the synthesis of Diclofenac’s glucuronide metaoblite.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kenny, J.R., et al.: J. Med. Chem., 47, 2816 (2004),<br></p>Fórmula:C23H23Cl2NO8Cor e Forma:NeatPeso molecular:512.34Mosapride N-Oxide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Mosapride (M731000).<br>References Chen, H., et al.: J. Pharm. Biomed. Anal., 40, 142 (2006), Pedraglio, S., et al.: J. Pharm. Biomed. Anal., 44, 665 (2007), Christopher, L., et al.: Drug Metab. Dispos., 36, 1341 (2008), Curran, M., et al.: Drugs, 68, 981 (2008),<br></p>Fórmula:C21H25ClFN3O4Cor e Forma:NeatPeso molecular:437.891,3-Bis(trimethylsilyl)urea
CAS:Produto Controlado<p>Applications 1,3-Bis(trimethylsilyl)urea (cas# 18297-63-7) is a useful research chemical.<br></p>Fórmula:C7H20N2OSi2Pureza:>85%Cor e Forma:NeatPeso molecular:204.42Kinetin Riboside
CAS:Produto Controlado<p>Applications Used as an anticancer and antiviral agent.<br>References Cancer Res., 20, 1362 (1960), Virology, 38, 26 (1969),<br></p>Fórmula:C15H17N5O5Cor e Forma:NeatPeso molecular:347.331-Naphthoyl Chloride
CAS:<p>Applications 1-Naphthoyl Chloride acts as a reagent in the preparation of tetrandrine derivatives as antitumor agents against human hepatocellular carcinoma. Identification of acylthiourea derivatives as potent Plk1 PBD inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lan, J., et al.: Eur. J. Med. Chem., 127, 554 (2017); Yun, T., et al.: Eur. J. Med. Chem., 124, 229 (2016)<br></p>Fórmula:C11H7ClOCor e Forma:NeatPeso molecular:190.632-Methyl Hippuric Acid-d2
CAS:Produto Controlado<p>Applications The main labelled metabolite of o-xylene.<br>References Gregus, Z., et al.: Drug Metab. Dispos., 26, 1082 (1998), Gregus, Z., et al.: Xenobiotica, 29, 547 (1999), Gonzalez-Reche, L., et al.: Arch. Toxicol., 77, 80 (2003),<br></p>Fórmula:C10D2H9NO3Cor e Forma:White To Off-WhitePeso molecular:195.21Ethynyl Estradiol 3-Sulfate Sodium Salt (>85%)
CAS:Fórmula:C20H23NaO5SPureza:>85%Cor e Forma:White To Light OrangePeso molecular:398.451,2-Diaminonaphthalene
CAS:Produto Controlado<p>Applications Reacts with aldehydes to produce highly fluorescent imidazole derivatives. A fluorometric labeling reagent. It is used for fluorophotometric determination of selenium in some kinds of mushroom.<br>References Lehmann, S., et al.: J. Biol. Chem., 272, 21479 (1997), Ragg, E., et al.: Eur. J. Biochem., 266, 1192 (1999), Tagliavini, F., et al.: J. Mol. Biol., 300, 1309 (2000),<br></p>Fórmula:C10H10N2Cor e Forma:NeatPeso molecular:158.20Methyl(4-methylnaphthalen-1-ylmethyl)amine
CAS:Produto Controlado<p>Applications Methyl(4-methylnaphthalen-1-ylmethyl)amine is a reagent in the preparation of heterocyclic compounds as enoyl-acyl carrier protein reductase FabI inhibitors and antibacterial agents.<br>References Stuetz, A., et al.: J. Med. Chem., 29, 112 (1986); Berman, J., et al.: PCT Int. Appl., 2004:515512 (2004)<br></p>Fórmula:C13H15NCor e Forma:NeatPeso molecular:185.26Carboxybutyrolactone
CAS:Produto Controlado<p>Applications Carboxybutyrolactone is a structural analog of (±)-Paraconic Acid (P191200) and is used as a reagent in the synthesis of methylenecarboxybutyrolactones which have antibacterial activity.<br>References Tonari, K., et al.: J. Oleo Sci., 51, 259 (2002)<br></p>Fórmula:C5H6O4Cor e Forma:Off-WhitePeso molecular:130.14,4'-Di-tert-butyl-2,2'-bipyridine
CAS:Produto Controlado<p>Applications 4,4'-Di-tert-butyl-2,2'-bipyridine acts as a reagent in the preparation, antiproliferative and cytotoxic activity of apoptotic ruthenium nitrogen heterocyclic complexes via combinatorial library synthesis.<br>References Mulcahy, S. P., et al.: Dalton Trans., 39, 177 (2010)<br></p>Fórmula:C18H24N2Cor e Forma:NeatPeso molecular:268.4α-Citral
CAS:<p>Applications α-Citral is an intermediate in the synthesis of 4,8-Dimethyl-1,3(E),7-nonatriene (D475810), which is a volatile compound released by corn plants in response to predation.<br>References Alborn, H,T,. et al.: Science, 276, 945 (1997)<br></p>Fórmula:C10H16OCor e Forma:Colourless To Light YellowPeso molecular:152.24Vitamin B2 (Riboflavin) 13C4 ,15N2
CAS:Produto ControladoFórmula:C4C13H2015N2N2O6Cor e Forma:NeatPeso molecular:382.322-Naphthylamine
CAS:<p>Applications It is listed as a known human carcinogen. Used in manufacturing of dyes, as antioxidant in rubber.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References IARC Monographs, 4, 97 (1974),<br></p>Fórmula:C10H9NCor e Forma:RedPeso molecular:143.192-Hydroxy-4’,5-diacetamido-diphenyl Ether
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 2-Hydroxy-4’,5-diacetamido-diphenyl Ether is used in the synthesis of novel benzimidazoles as potent inhibitors of TIE-2 anf VEGFR-2 tyrosine kinase receptors. Angiogenesis therapeutic agent.<br>References Hasegawa, M. et al.: J. Med. Chem., 50, 4453 (2007);<br></p>Fórmula:C16H16N2O4Cor e Forma:NeatPeso molecular:300.31(1R)-(+)-a-Pinene (~80% ee)
CAS:Produto Controlado<p>Applications (1R)-(+)-α-Pinene is used in hydroboration reactions and the reduction of ketones.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Brown, H. et al.: J. Org. Chem., 50, 1384 (1985);<br></p>Fórmula:C10H16Cor e Forma:NeatPeso molecular:136.23Hydroxy Urea-13C,15N2
CAS:Produto Controlado<p>Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Fórmula:CH4N2O2Cor e Forma:Off White SolidPeso molecular:79.03Tridecanoic-d25 Acid
CAS:Produto Controlado<p>Applications Isotope labelled Tridecanoic Acid, commonly found in dairy products. It is also a useful synthetic intermediate. It is used to synthesize Testosterone Tridecanoate (T55180).<br>References Kliem, K., et al.: Food Chem., 141, 274 (2013);<br></p>Fórmula:C13D25HO2Cor e Forma:NeatPeso molecular:239.5Mycophenolic Acid Phenolic β-D-Glucoside
CAS:Produto ControladoFórmula:C23H30O11Cor e Forma:White To Off-WhitePeso molecular:482.48Indole-2,4,5,6,7-d5-3-acetic Acid
CAS:Produto Controlado<p>Applications Indole-2,4,5,6,7-d5-3-acetic Acid is an isotopic analog of Indoleacetic Acid (I577340) which is the most common and naturally occuring plant hormone in the auxin class of hormones. It effects cell elongation, cell division as well as plant growth and development.<br></p>Fórmula:C102H5H4NO2Cor e Forma:NeatPeso molecular:180.213,3-Bis(2-hydroxyethyl)urea
CAS:Produto Controlado<p>Applications 3,3-bis(2-hydroxyethyl)urea (cas# 23270-55-5) is a useful research chemical.<br></p>Fórmula:C5H12N2O3Cor e Forma:NeatPeso molecular:148.16O,O-Dimethyl Dithiophosphate-13C2 Ammonium salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Labelled dimethyl phosphorodithiolate derivatives used as insecticides.<br></p>Fórmula:C2H10NO2PS2Cor e Forma:Off-WhitePeso molecular:177.201-Nitropiperazine-d8
CAS:Produto Controlado<p>Applications Labelled nitro substituted piperazine.<br></p>Fórmula:C4HD8N3O2Cor e Forma:NeatPeso molecular:139.184-tert-Butylacetophenone
CAS:Produto Controlado<p>Applications 4-tert-Butylacetophenone is an impurity arising in the synthesis of Ebastine (E320000). Ebastine impurity B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C12H16OCor e Forma:ColourlessPeso molecular:176.252,5-Dinitrophenol (Wetted with water >15%)
CAS:Produto Controlado<p>Applications 2,5-Dinitrophenol (wetted with ca. 20% Water) (unit weight on dry weight basis) is a useful reagent for the preparation of yttrium nitrophenolate aminebis(benzotriazolylphenolate) complexes.<br> E0<br>References Su, Y. C., et al.: J. Polym. Sci. A Polym. Chem., 57, 2038 (2019)<br></p>Fórmula:C6H4N2O5Cor e Forma:NeatPeso molecular:184.119-cis-Retinyl Stearate-d5
CAS:Produto Controlado<p>Applications 9-cis-Retinyl Stearate-d5, is the labeled analogue of 9-cis-Retinyl Stearate (R275600), a fatty acid ester of Retinol isomer, found mainly in the retina.<br>References Bridges, C.D.B., et al.: Methods Enzymol., 81, 463 (1982),<br></p>Fórmula:C38D5H59O2Cor e Forma:NeatPeso molecular:557.9443-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid
CAS:Produto Controlado<p>Applications 3-[2-N-(Biotinyl)aminoethyldithio]propanoic Acid (cas# 104582-29-8) is a compound useful in organic synthesis.<br>References Kobayashi, N., et al.: Anal. Biochem., 357, 311 (2006),<br></p>Fórmula:C15H25N3O4S3Cor e Forma:NeatPeso molecular:407.57Dimethachlor Ethane Sulfonic Acid Sodium Salt-d6
CAS:Produto Controlado<p>Applications Dimethachlor Ethane Sulfonic Acid Sodium Salt-d6 is the deuterium labelled form of Dimethachlor Ethane Sulfonic Acid Sodium Salt (D460283), which is a pesticide metabolite and pollutant found in groundwater, surface water, and wastewater.<br>References Huntscha, S., et al.: J. Chromatogr. A, 1268, 74 (2012); Reemtsma, T., et al.: J. Chromatogr. A, 1271, 95 (2013);<br></p>Fórmula:C13D6H12NNaO5SCor e Forma:Off White SolidPeso molecular:329.383-Hydroxy Loratadine
CAS:Produto Controlado<p>Applications An intermediate for the preparation of 3-Hydroxy Desloratadine.<br></p>Fórmula:C22H23ClN2O3Cor e Forma:NeatPeso molecular:398.885,8-Epoxy-13-cis Retinoic Acid(Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications A metabolite of 13-cis-Retinoic Acid (R250000).<br>References Samokyszyn, V., et al.: J. Biol. Chem., 262, 14119 (1987), Oldfield, N., et al.: Drug Metabol. Dispos., 18, 1105 (1990), Samokyszyn, V., et al.: Chem. Res. Toxicol., 10, 795 (1997),<br></p>Fórmula:C20H28O3Cor e Forma:NeatPeso molecular:316.43Beta-Estradiol 17-(Beta-D-Glucuronide) Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications beta-Estradiol 17-(beta-D-glucuronide) sodium salt is a glucocorticosteroid analog.<br></p>Fórmula:C24H31NaO8Cor e Forma:NeatPeso molecular:470.495’-Deoxyfluorouridine-13C,15N2
CAS:Produto Controlado<p>Applications 5’-Deoxyfluorouridine-13C,15N2 is a compound useful in organic synthesis.<br></p>Fórmula:C8CH11FN2O5Cor e Forma:NeatPeso molecular:249.17Pteroyltri-γ-L-glutamic acid (>85%)
CAS:<p>Applications Pteroyltri-γ-L-glutamic acid is a folate derivative found in various foods such as yeast, spinach, beef liver, beef fillet and peas.<br>References Tamura, T., et al.: Br. J. Haematol., 25, 513 (1973); Ndaw, S., et al.: J. Chromatogr. A, 928, 77 (2001)<br></p>Fórmula:C29H33N9O12Pureza:>85%Cor e Forma:Off WhitePeso molecular:699.625Vitamin K1 Hydroxide
CAS:Produto Controlado<p>Stability Temperature and Light Sensitive, unstable in solution<br>Applications Vitamin K1 Hydroxide is a derivative of Vitamin K1 (V676080), which occurs widely in green plants, algae, and photosynthetic bacteria.<br>References Hassan, M.M.A., et al.: Anal. Profiles Drug Subs., 17, 449 (1988), Breton, J., et al.: Biochemistry, 33, 12405 (1994), Dowd, P., et al.: Science, 269, 1684 (1995),<br></p>Fórmula:C31H46O3Cor e Forma:NeatPeso molecular:466.7
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