
Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.474 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.603 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.602 produtos)
- Toxicologia(13.653 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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4-Bromobenzoic Acid Methyl Ester
CAS:<p>Applications 4-Bromobenzoic Acid Methyl Ester is halogenated benzoate used as a reagent in organic synthesis. 4-Bromobenzoic Acid Methyl Ester can be used to stimulate microbial dechlorination of PCBs. 4-Bromobenzoic Acid Methyl Ester is also used in the preparation of stable radioiodinating reagent to label monoclonal antibodies for radiotherapy of cancer.<br>References Wilbur, D.S. et al.: J. Nuclear Med., 30, 216 (1989); DeWeerd, K.A. et al.: Environ. Sci. Technol., 33, 2057 (1999);<br></p>Fórmula:C8H7BrO2Cor e Forma:Off-WhitePeso molecular:215.045-Oxorosuvastatin Methyl Ester
CAS:<p>Applications 5-Oxorosuvastatin methyl ester is an intermediate in the synthesis of Rosuvasatatin (calcium salt: R700500), a 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that decreases high-sensitivity C-reactive protein (hsCRP) and cholesterol concentrations in the blood.<br>References McTaggart, F., et al.: Am. J. Cardiol., 87, 28 (2001); Ridker, P., et al.: Lancet, 373, 1175 (2009)<br></p>Fórmula:C23H28FN3O6SCor e Forma:Yellow SolidPeso molecular:493.55Hydroxy Dehydro Nifedipine Lactone
CAS:Produto ControladoFórmula:C16H12N2O6Cor e Forma:NeatPeso molecular:328.28Dehydro Nicardipine Hydrochloride
CAS:<p>Impurity Nicardipine USP Related Compound B<br>Applications A pyridine metabolite M-5 of Nicardipine. Nicardipine USP Related Compound B.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Triggle, A., et al.: J. Med. Chem., 23, 1442 (1980), Freedman, D., et al.: Drugs, 34, 578 (1987), Guengerich, F., et al.: Xenobiotica, 25, 689 (1995), Schleifer, K., et al.: Pharmazie, 54, 804 (1999),<br></p>Fórmula:C26H27N3O6·ClHCor e Forma:NeatPeso molecular:513.97(3R,5R)-Rosuvastatin Sodium Salt
CAS:<p>Impurity Rosuvastatin EP Impurity B<br>Stability Hygroscopic<br>Applications A diastereomer of Rosuvastatin (R700500) used for treatment, prevention and combination therapy of lipid-related disorders. Rosuvastatin EP Impurity B<br></p>Fórmula:C22H27FN3NaO6SCor e Forma:White To Light YellowPeso molecular:503.52Bilirubin (>90%)
CAS:Produto Controlado<p>Applications Principal pigment of bile and constituent of many biliary calculi.<br>References Stenhagen, R., et al.: Biochem. J., 33, 1591 (1939), Gray, et al.: J. Chem. Soc., 2264, 2268 (1961),<br></p>Fórmula:C33H36N4O6Pureza:>90%Cor e Forma:NeatPeso molecular:584.662N,N'-Di-tert-Butylurea
CAS:Produto Controlado<p>Applications N,N'-Di-tert-Butylurea can be used in synthetic preparation and structural characterization of polynuclear gold and bimetallic gold/silver complexes for carbon-hydrogen functionalization of carbonyl compounds and homogeneous carbonylation of amines.<br>References Smirnova, E., et al.: Angew Chem Int Edit, 55, 7487 (2016)<br></p>Fórmula:C9H20N2OCor e Forma:White To Off-WhitePeso molecular:172.268Ciprofibrate Ethyl Ester
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Ciprofibrate Ethyl Ester is an impurity of ciprofibrate(C482475) is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.<br>References Davison, C., et al.: Drug. Metab. Dispos., 3, 520 (1975), Arnold, A., et al.: J. Pharm. Sci., et al.: 68, 1557 (1979), Tuchman-Duplessis, H., et al.: Toxicology, 12, 1 (1979),<br></p>Fórmula:C15H18Cl2O3Cor e Forma:Colourless To Off-WhitePeso molecular:317.21Methyl Benzilate
CAS:Produto Controlado<p>Applications Methyl Benzilate is a reactant in the synthesis of Trimethadione (T796155), an anticonvulsant and antiepileptic agent used in the treatment of pregnant women. Prenatal exposure to snti-epileptic drugs (AEDs) has indicated increased risk of major or minor congenital malformation.<br>References Pastore, V., et. al.: Bioorg. Med. Chem., 21, 841 (2013); Ahir, B. et al.: Toxicol. Vitro., 28, 948 (2014); Pastore, V. et al.: Bioorg. Med. Chem., 21, 841 (2013)<br></p>Fórmula:C15H14O3Cor e Forma:Off White PowderPeso molecular:242.272-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid
CAS:Produto Controlado<p>Applications 2-[3-(Aminosulfonyl)-4-chlorobenzoyl]-benzonic Acid is a potential metabolite of Chlorthalidone.<br>References Salado C., et al.: J. Chromatography. Biomed. App., 690, 195 (1997);<br></p>Fórmula:C14H10ClNO5SCor e Forma:NeatPeso molecular:339.75Nicergoline-d3
CAS:Produto Controlado<p>Applications Nicergoline-d3 is the labeled analogue of Nicergoline(N394550), a drug used for age-dependent cognitive impairment such as Alzheimers disease and other types of dementia.<br>References Caraci, F., et. al.: Brain Res., 1047, 30 (2005); Mizuno, T., et. al.: Brain Res., 1066, 78 (2005)<br></p>Fórmula:C24D3H23BrN3O3Cor e Forma:NeatPeso molecular:487.4044-(Methoxy-d3)-α-methyl-benzeneethanamine Hydrochloride
CAS:Produto Controlado<p>Applications 4-(Methoxy-d3)-α-methyl-(αS)-benzeneethanamine Hydrochloride is the labelled form of 4-Methoxyamphetamine Hydrochloride (M261015), which is the HCl salt of 4-Methoxyamphetamine. 4-Methoxyamphetamine is a designer drug belonging to the amphetamine class and releases 5-hydroxytryptamine in brain tissue.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Menon, M., et al.: J. Pharmacol. Exp. Ther., 197, 272 (1976);<br></p>Fórmula:C10H12D3NO·HClCor e Forma:Off-WhitePeso molecular:204.71N-Desmethyl Clomipramine Hydrochloride
CAS:Produto Controlado<p>Applications A metabolite of Clomipramine.<br>References McTavish, D., et al.: Drugs, 39, 136 (1990), Chauret, N., et al.: Drug Metab. Dispos., 25, 1130 (1997), Gex-Fabry, M., et al.: Ther. Drug Monit., 22, 701 (2000), Herrera, D., et al.: J. Clin. Pharmacol., 40, 1488 (2000),<br></p>Fórmula:C18H21ClN2·ClHCor e Forma:Off-WhitePeso molecular:337.2922-Hydroxy Mifepristone
CAS:Produto Controlado<p>Applications A metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C29H35NO3Cor e Forma:NeatPeso molecular:445.594-(S)-1-Des(methylamine)-1-oxo-2-(R,S)-hydroxy Sertraline
CAS:Produto ControladoFórmula:C16H12Cl2O2Cor e Forma:NeatPeso molecular:307.17Indole-3-acetic acid Sodium Salt
CAS:Produto Controlado<p>Stability Temperature Sensitive<br>Applications Indole-3-acetic acid is a plant growth regulator. It induces cell division and cell elongation that promotes plant growth.<br>References Fawcett, C., et al.: Nature, 178, 972 (1956); Fawcett, C., et al.: Annals Appl. Bio., 43, 342 (1955); Korshak, V., et al.:Vysokomolekulyarnye Soedineniya, Seriya B: Kratkie Soobshcheniya, 22, 791 (1980)<br></p>Fórmula:C10H8NNaO2Cor e Forma:White To Off-WhitePeso molecular:197.17Perilla Ketone
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Perilla Ketone is an oil from Perilla frutescens which is very toxic as it is a potent pulmonary edemagenic agent for laboratory animals and livestock. This compound is commonly used in oriental foods.<br>References Wilson, B.J., et al.: Science, 197, 573 (1997)<br></p>Fórmula:C10H14O2Cor e Forma:NeatPeso molecular:166.2219-Norandrosterone
CAS:Produto Controlado<p>Applications 19-Norandrosterone is the oxidized byproduct of Nandrolone (N315000), an anabolic steroid that is present naturally in the human body.<br>References Jiang, J.Q., et al.: J. Food. Sci., 77, 63 (2012); Delgadillo, M.A., et al.: J. Chromatograph. Anal. Technol. Biomed. Life. Sci., 897 (2012);<br></p>Fórmula:C18H28O2Cor e Forma:NeatPeso molecular:276.41(±)-trans-α-Bergamotene
CAS:Produto Controlado<p>Applications (±)-trans-α-Bergamotene is an essential oil from medicinal plants of Cameroon.<br>References Boyom, F. F., et al.: Phytochem., 64, 1269 (2003);<br></p>Fórmula:C15H24Cor e Forma:NeatPeso molecular:204.351Atorvastatin Ethyl Ester
CAS:Produto Controlado<p>Applications Atorvastatin (A791750) impurity.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996);<br></p>Fórmula:C35H39FN2O5Cor e Forma:Off White SolidPeso molecular:586.696α-Hydroxy Progesterone (>80%)
CAS:Produto ControladoFórmula:C21H30O3Pureza:>80%Cor e Forma:NeatPeso molecular:330.461,3-Diacetyl Aloe-emodin
CAS:Produto Controlado<p>Applications 1,3-Diacetyl Aloe-emodin is an intermediate in the synthesis of Aloe Emodin 8-Glucoside which is a anthraquinone glycoside that was investigated for antioxidant activities and neuroprotective properties.<br>References El-Toumy, S.A., et al.: Carb. Res. 360, 47 (2012); Xiang, L., et al: TsingHua. Sci. Tech., 10, 426 (2005); Shi, Y.Q., et al: Anticancer. Res., 21, 2847 (2001);<br></p>Fórmula:C10H17BO2Cor e Forma:NeatPeso molecular:180.0524-Methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic Acid
CAS:Produto Controlado<p>Applications 4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-carboxylic acid (cas# 144059-86-9) is a useful research chemical.<br></p>Fórmula:C12H8F3NO2SCor e Forma:NeatPeso molecular:287.26Methyl-2-naphthalenemethylamine Hydrochloride
CAS:Produto Controlado<p>Applications An intermediate in the preparation of detoxification inhibitors of the crucifer phytoalexin Brassinin, as potential fungicides against Leptosphaeria maculans.<br>References Gaspari, P., et al.: J. Med. Chem., 49, 684 (2006), Pedras, M., et al.: Bioorg. Med. Chem., 14, 714 (2006),<br></p>Fórmula:C12H14ClNCor e Forma:NeatPeso molecular:207.7(BetaR,DeltaR,1S,2S)-1,2-Dihydro-β,δ,6-trihydroxy-2-methyl-1-naphthaleneheptanoic Acid Sodium Salt (Pravastatin Impurity)
CAS:Produto Controlado<p>Applications Pravastatin impurity.<br>References Muramatsu, S., et al.: Biol. Pharm. Bull., 20, 1199 (1997), Serajuddin, A., et al.: J. Pharm. Sci., 88, 696 (1999),<br></p>Fórmula:C18H23O5·NaCor e Forma:NeatPeso molecular:342.36Terazosin-md
Produto Controlado<p>Applications Terazosin-md is an analog of Terazosin (T105000) which is an α1-adrenergic receptor antagonist alleviating organ damage in studies done on rodent models of stroke and sepsis and has potential to be used for treatment for diseases.<br>References Chen, X., et al.: Nat. Chem. Biol, 11, 19 (2015)<br></p>Fórmula:C20H26N4O4Cor e Forma:NeatPeso molecular:386.4452,3-Dibromoanthracene
CAS:Produto Controlado<p>Applications 2,3-Dibromoanthracene is a useful synthetic intermediate. It is used to synthesize various acenes and acene derivatives such as Acenaphth[1,2-b]anthracene (A130745) which is mutagenic.<br>References Toyota, S., et al.: Sci. Syn., 45, 745 (2010); Durant, J., et al.: Mutat. Res-Genet. Tox., 371, 123 (1996)<br></p>Fórmula:C14H8Br2Cor e Forma:NeatPeso molecular:336.02Rosuvastatin Triphenylphosphonium Bromide
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications An intermediate in the production of Rosuvastatin (R700500) derivatives.<br></p>Fórmula:C34H34FN3O2PS·BrCor e Forma:WhitePeso molecular:678.59Thiamine Acetate Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Thiamine (T344185) impurity.<br>References Warnock, L., et al.: Anal. Biochem., 126, 394 (1982), Royer-Morrot, J., et al.: Eur. J. Clin. Pharmacol., 42, 219 (1992),<br></p>Fórmula:C14H20Cl2N4O2SCor e Forma:WhitePeso molecular:379.31Magnesium Carbonate
CAS:Produto Controlado<p>Applications Magnesium Carbonate is a chemical reagent used in the production of magnesium oxide in the synthesis of ceramics.<br>References Seabra, M. et al.: Mat. Res. Bull., 37, 255 (2002); Kumar, T. et al.: Biomat., 21, 1623 (2000);<br></p>Fórmula:CO3·MgCor e Forma:White To Off-WhitePeso molecular:84.311, N6-Etheno-2'-deoxyadenosine-13C5
Produto Controlado<p>Applications 1, N6-Etheno-2’-deoxyadenosine-13C5 is caused by exposure to pollutants. It is an isotopically labeled analog of the 2’-Deoxyguanosine adduct.<br></p>Fórmula:C713C5H13N5O3Cor e Forma:NeatPeso molecular:280.236β-Hydroxy-21-desacetyl Deflazacort
CAS:<p>Applications The major metabolite of Deflazacort.<br>References Bernareggi, A., et al.: J. Pharma. Biomed. Anal., 5, 177-81 (1987), Assandri, A., et al.: Xenobiotica, 13(3), 185 (1983), Martinelli, E., et al.: Drug Metab. Dispos., 7, 335 (1979),<br></p>Fórmula:C23H29NO6Cor e Forma:NeatPeso molecular:415.48Diamino-5-phenylthiazole Hydrobromide
CAS:Produto Controlado<p>Applications Diamino-5-phenylthiazole Hydrobromide is an phenylthiazole derivative used in the preparation of antiallergic and antiinflammatory agents.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ban, M. et al.: Bioorg. Med. Chem., 6, 1069 (1998);<br></p>Fórmula:C9H9N3S·BrHCor e Forma:NeatPeso molecular:272.16Digoxigenin Monodigitoxoside
CAS:Produto Controlado<p>Applications A metabolite of Digoxin (Dx) (D446575).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fujii, Y., et al.: Clin. Chem., 37, 476 (1991), Salphati, L., et al.: Xenobiotica, 29, 171 (1999), Song, S., et al.: Drug Metab. Dispos., 27, 689 (1999),<br></p>Fórmula:C29H44O8Cor e Forma:BeigePeso molecular:520.65Boldenone Propionate
CAS:Produto Controlado<p>Applications Boldenone Propionate is a metabolite of Boldenone (B675100), which is an anabolic steroid.<br>References Watanabe, K., et al.: J. Appl. Bacteriol., 62, 151 (1987) ; Liu, W., et al.: J. Ind. Microbiol., 13, 167 (1994) ; Barthakur, S., et al.: J. Basic Microbiol., 36, 383 (1996); Grinenko, G., et al.: Pharmaceut. Chem. J., 36, 510 (2002) ; de Brabander, H., et al.: Food Addit. Contam., 21, 515 (2004); Le Bizec, B., et al.: Steroids, 71, 1078 (2006);<br></p>Fórmula:C22H30O3Cor e Forma:Off-WhitePeso molecular:342.47Polythiazide
CAS:Produto Controlado<p>Applications Polythiazide is a thiazide diuretic. Polythiazide is used in the treatment of hypertension as well as nephrotic syndrome, cirrhosis of the liver, and nutritional edema.<br>References Kaur, J. et al.: J. Ind. Med. Assoc., 48, 13, (1967); Lund-Johansen, P.: Acta Med. Scand., 187, 509 (1970); O'Brien, E.T. et al.: Br. Heart J., 34, 1042 (1972);<br></p>Fórmula:C11H13ClF3N3O4S3Cor e Forma:Off WhitePeso molecular:439.88Droxicam
CAS:Produto Controlado<p>Applications Droxicam is a non-steroidal anti-inflammatory drug.<br>References Lapeyre-Mestre, M., et. al.: Fundam. Clin. Pharm., 20, 391 (2006)<br></p>Fórmula:C16H11N3O5SCor e Forma:Off-White To Light YellowPeso molecular:357.341,2,5,6-Tetramethylnaphthalene
CAS:Produto Controlado<p>Applications 1,2,5,6-Tetramethylnaphthalene is a polycyclic aromatic hydrocarbon that has been found in petroleum.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Forster, P.G., et. al.: J. Chromatogr., 483, 384 (1989)<br></p>Fórmula:C14H16Cor e Forma:NeatPeso molecular:184.2772,2'-((4-Aminophenyl)azanediyl)diethanol Sulfate
CAS:Produto ControladoFórmula:C10H16N2O2·H2O4SCor e Forma:White To Off-WhitePeso molecular:294.32473,3',5,5'-Tetramethyl[1,1'-biphenyl]-4,4'-diol
CAS:Produto Controlado<p>Applications 3,3',5,5'-Tetramethyl[1,1'-biphenyl]-4,4'-diol, is a building block used in chemical synthesis of Mexiletine (M340800) and it’s derivatives.<br></p>Fórmula:C16H18O2Cor e Forma:NeatPeso molecular:242.31N-(n-Butanesulfonyl)-O-[4-(4-pyridinyl)-butyl]-(S)-tyrosine
CAS:<p>Applications Tirofiban intermediate.<br></p>Fórmula:C22H30N2O5SCor e Forma:NeatPeso molecular:434.551,2-Dihydro Beclomethasone Dipropionate
CAS:Produto Controlado<p>Impurity Beclomethasone Dipropionate EP Impurity L<br>Applications 1,2-Dihydro Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity L) is an impurity of Beclomethasone Dipropionate (B131030).<br></p>Fórmula:C28H39ClO7Cor e Forma:NeatPeso molecular:523.06Edoxaban Tosylate Monohydrate
CAS:<p>Applications Edoxaban is an anticoagulant drug which acts as a direct factor Xa inhibitor.<br>References Ruff, C., et al.: Am. Heart J., 160, 635 (2010); Ogata, K., et al.: J. Clin. Pharm., 50, 73 (2010)<br></p>Fórmula:C31H38ClN7O7S2•xH2OCor e Forma:White To Off-WhitePeso molecular:720.267α-Hydroxy-4-cholesten-3-one
CAS:<p>Applications 7α-Hydroxy-4-cholesten-3-one is a metabolite of Cholesterol (C432501).<br>References Connor, W., et al.: J, Clin. Invest., 48, 1363 (1969), Nestel, P., et al.: Metabolism, 24, 189 (1975), Ellegard, L., et al.: Eur. J. Clin. Nutr., 45, 451 (1991), Pedersen, A., et al.: J. Lipid Res., 41, 1901 (2000),<br></p>Fórmula:C27H44O2Cor e Forma:NeatPeso molecular:400.64Desloratadine N-Hydroxypiperidine
CAS:<p>Applications A related compound of Desloratadine (D290250).<br>References Krishna, K., et al.: J. Pharm. Biomed. Anal., 32, 29 (2003), Qi, M., et al.: J. Pharm. Biomed. Anal., 38, 355 (2005),<br></p>Fórmula:C19H19ClN2OCor e Forma:NeatPeso molecular:326.824-Aminoacetophenone
CAS:Produto Controlado<p>Applications A novel utilization of aminophenone derivative in toxicology, for treating intoxications with cyanogenic toxic substances.<br>References Donoghue, N., et al.: Eur. J. Biochem., 60, 1 (1975), Chen, Y., et al.: J. Bacteriol., 170, 781 (1988),<br></p>Fórmula:C8H9NOCor e Forma:Yellow SolidPeso molecular:135.163-Dehydro Retinal
CAS:Produto Controlado<p>Stability Light Sensitive, Temperature Sensitive<br>Applications An oxidized derivative of the visual pigment carotenoid.<br>References Wada, A., et al.: Chem. Pharm. Bull., 56, 112 (2008), Smolensky, E., et al.: Biochem., 48, 9170 (2009),<br></p>Fórmula:C20H26OCor e Forma:NeatPeso molecular:282.42
