Glicociência
A glicociência é o estudo dos carboidratos e seus derivados, bem como das interações e funções biológicas em que participam. Este campo de pesquisa é crucial para compreender uma ampla variedade de processos biológicos, incluindo o reconhecimento celular, a sinalização, a resposta imune e o desenvolvimento de doenças. A glicociência tem aplicações importantes na biotecnologia, na medicina e no desenvolvimento de novos medicamentos e terapias. Na CymitQuimica, oferecemos uma ampla seleção de produtos de alta qualidade e pureza para pesquisa em glicociência. Nosso catálogo inclui monossacarídeos, oligossacarídeos, polissacarídeos, glicoconjugados e reagentes específicos, projetados para apoiar os pesquisadores em seus estudos sobre a estrutura, função e aplicações dos carboidratos em sistemas biológicos. Esses recursos são destinados a facilitar descobertas científicas e aplicações práticas em diversas áreas das biociências e da medicina.
Subcategorias de "Glicociência"
- Amino açúcares(108 produtos)
- Anticorpos Glico-Relacionados(282 produtos)
- Glicolípidos(46 produtos)
- Glicosaminoglicanos (GAGs)(55 produtos)
- Glicosídeos(419 produtos)
- Monossacáridos(6.616 produtos)
- Oligossacarídeos(3.718 produtos)
- Polissacáridos(505 produtos)
Foram encontrados 11017 produtos de "Glicociência"
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N-Acetylneuraminic acid dimer 1-O-propylamine
N-Acetylneuraminic acid dimer 1-O-propylamine is a synthetic N-acetylneuraminic acid (NANA) derivative that has been modified with an alkyl amine. This modification prevents the formation of NANA oligosaccharides and is used in the synthesis of complex carbohydrates. It is also used as a fluorinated building block for various saccharides, including monosaccharides, disaccharides, and polysaccharides. The purity of this product is greater than 99%.Pureza:Min. 95%LS-tetrasaccharide c ammonium salt
CAS:Sialylated tetrasaccharide found in human milk, possible health benefits for the neonate by supporting resistance to pathogens, gut maturation, immune function, and cognitive development.Fórmula:C37H62N2O29•NH3Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:1,015.88 g/mol9-O-Acetyl-N-acetyl-neuraminic acid
CAS:9-O-Acetyl-N-acetyl-neuraminic acid is a sialic acid produced by the human body. It can be found in human serum and has been shown to have inhibitory properties against viruses, such as hepatitis B and C viruses. 9-O-Acetyl-N-acetylneuraminic acid binds to the α1-acid glycoprotein in the blood, which can reduce its ability to bind to other molecules. This leads to a lower concentration of 9-O-acetylneuraminic acid in the blood. This molecule also has chemical biology properties that are being studied for their effects on biological processes such as histological analysis, receptor molecule binding, polymerase chain reaction (PCR), and mucin gene transcription. 9-O-Acetylneuraminic acid also has antihistamine activities that may be due to its ability to block histamine receptors or inhibit histamine release.Fórmula:C13H21NO10Pureza:Min. 75 Area-%Cor e Forma:White Off-White PowderPeso molecular:351.31 g/mol(5R, 8R, 9S) -8- [(4R) - 2, 2-Dimethyl- 1, 3- dioxolan- 4- yl] - 9- hydroxy- 2, 2- dimethyl- 1, 3, 7- trioxaspiro[4.4] nonan- 6- one
5,8-Dihydroxy-6-fluoro-2,2-dimethyl-1,3,7-trioxaspiro[4.4]nonane - 8-[(4R)-2,2-dimethyl-1,3-dioxolan-4-yl]-9-(hydroxymethyl) - 2,2-dimethyl - 1,3,7 - trioxaspiro[4.4]nonane is a synthetic glycosylated fluorinated octahydropyrrole (5R)-8-(hydroxymethyl)-9-(hydroxymethyl)-6-[(methyloxy)methyl]-2,2,- dimethylpiperidine that is used as an intermediate in the synthesis of oligosaccharides and polysaccharides. It is also used to modify complex carbohydrates for click chemistry applications. This product has a CAS number of 9248411–67–0 and a purity of >Pureza:Min. 95%(1S) -1- [(2S, 3R,4S) -4-(Acetoxy)methyl-3-benzyloxy- N-benzyl-1- azetidinyl] -di-O-acetyl-1, 2- ethanediol
1,2-Ethanediol is a polyhydroxy alcohol that is used in the synthesis of complex carbohydrates. It can be found as an Oligosaccharide in plants, which are composed of three or more sugar molecules. 1,2-Ethanediol is also found in the glycosylation reaction for the modification of saccharides and carbohydrates. This process adds glucose to a protein or peptide molecule through a condensation reaction with the amino acid N-acetylglucosamine. Glycosylation usually occurs in animal cells, but can also occur in plants and microorganisms. The addition of methyl groups by Methylation to 1,2-ethanediol is used to create Methylated derivatives of this compound. A click modification to this compound can be done using a Copper(I) azide complex and an alkyne reagent to add a terminal alkene group to 1,2-ethanediol. Fluorination atPureza:Min. 95%Isopropyl 2,5-anhydro-6-O-methanesulfonyl-D-gulonate
Isopropyl 2,5-anhydro-6-O-methanesulfonyl-D-gulonate is a compound that can be used as a monosaccharide and is also a synthetic sugar. It is an Oligosaccharide, which is a type of sugar that consists of more than two saccharide units. This compound has been synthesized by the process of glycosylation and has been modified to include fluorination. Click modification, methylation, and monosaccharide are all modifications that have been done to this sugar. Isopropyl 2,5-anhydro-6-O-methanesulfonyl-D-gulonate is also known by its CAS number: 106585-36-1.Pureza:Min. 95%GD2-Ganglioside
CAS:GD2 (shown as sodium salt) has a core trisaccharide structure (GalNAc-b-1,4-Gal-b-1,4-Glc) with its two sialic acids linked b-2,3/b-2,8 to the inner galactose residue and ceramide linked to position 1 on the reducing terminal glucose residue. GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 is overexpressed in a number of tumors, including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, it has been found in low concentrations on breast cancer stem cells (CSC) that possess: self-renewal properties (division without disrupting the undifferentiated state), and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).Fórmula:C78H138N4O34·xNaPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:1,675.94 g/mol3-Azido-3-deoxy-5, 6- O- isopropylidene- D- gulonic acid g- lactone
CAS:3-Azido-3-deoxy-5, 6-O-isopropylidene-Dgulonic acid g-lactone is a fluorinated monosaccharide. It is synthesized by the reaction between 3,4,6,7 tetra fluorobenzaldehyde and 5,6 O isopropylidene Dgulonic acid. It can be used for glycosylation reactions in order to produce oligosaccharides. The modification of this product can be achieved through methylation and sugar modification techniques. This product has CAS No. 244057-17-8 and is highly pure with a purity of 99%.Fórmula:C9H13N3O5Pureza:Min. 95%Peso molecular:243.22 g/molUDP-Gal 2Na
CAS:UDP-a-D-galactose disodium salt (UDP-Gal) is a sugar-nucleotide substrate of galactosyltransferases. It’s used as the donor of galactose in the biosyntheses of glycoproteins and glycolipids. Its low cellular content is also hypothetically linked to the defective galactosylation in galactosemia.
Fórmula:C15H22N2O17P2·2NaPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:610.27 g/mol1,2,3,4-Tetra-O-acetyl-6-O-(tert-butyldimethylsilyl)-b-D-glucopyranose
CAS:1,2,3,4-Tetra-O-acetyl-6-O-(tert-butyldimethylsilyl)-b-D-glucopyranose is a custom synthesis of an Oligosaccharide. It is a complex carbohydrate that has been modified with Methylation and Glycosylation. Carbohydrate Click chemistry has been used to modify the sugar molecule with Fluorination. This product is manufactured in high purity and can be used for pharmaceutical purposes.Fórmula:C20H34O10SiPureza:Min. 95%Peso molecular:462.57 g/molGlucosyl-C18-sphingosine
CAS:Glucosyl-C18-sphingosine is a sphingolipid that has been shown to inhibit the activity of Gaucher's enzyme, which is responsible for the synthesis of glucosylceramide. It has been demonstrated in a model system that glucosyl-C18-sphingosine inhibits mitochondrial membrane potential and decreases ATP levels, leading to cell death. The molecular pathogenesis of Gaucher disease is not well understood but it is believed to be related to defective lysosomal function. Glucosyl-C18-sphingosine may be used as a diagnostic agent for Gaucher disease and other metabolic disorders involving glucosylceramide accumulation.Fórmula:C24H47NO7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:461.63 g/mol2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucohydroximo-1,5-lactone
CAS:2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy-D-glucohydroximo-1,5-lactone is a methylated sugar. It is a white to off white powder with a molecular weight of 518. The chemical formula for 2-Acetamido-3,4,6-tri-O-acetyl-2-deoxy--D--glucohydroximo--1,5--lactone is C16H26N2O8 and the structural formula is as follows:br>Fórmula:C14H20N2O9Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:360.32 g/mol6-O-(2-Acetamido-2-deoxy-β-D-galactopyranosyl)-D-galactopyranose
CAS:6-O-(2-Acetamido-2-deoxy-b-D-galactopyranosyl)-D-galactopyranose is a fluorinated carbohydrate that belongs to the group of saccharides. It is a monosaccharide and can be custom synthesized for specific purposes. This product has been modified with click chemistry, methylation, and glycosylation. 6-O-(2-Acetamido-2-deoxy-b-D-galactopyranosyl)-D-galactopyranose is soluble in water and has high purity.Fórmula:C14H25NO11Pureza:Min. 90 Area-%Cor e Forma:PowderPeso molecular:383.35 g/mol4-O-Methyl-D-glucose
CAS:4-O-Methyl-D-glucose is an acidic sugar that is found in the cell walls of plants. It has been shown to have structural studies on plant cells, with ion-exchange and ester linkages. 4-O-Methyl-D-glucose is metabolized by microorganisms, including bacteria, fungi, and yeast. This sugar can be oxidized to form acid or oligosaccharides as well as oxidation products such as methylglyoxal. 4-O-Methyl-D-glucose is also used in the synthesis of mucopolysaccharides which make up the connective tissue of tumor cells. This sugar can be synthesized from D-mannose by a diazonium salt reaction followed by oxidation with sodium hypochlorite. The hydroxyl group on this sugar can be acetylated to form acetylated 4-O methyl glucose.Fórmula:C7H14O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:194.18 g/molN-Acetyl-D-[1,2,3-¹³C3]neuraminic acid
CAS:N-Acetyl-D-[1,2,3-¹³C3]neuraminic acid is a modification of the natural sugar N-acetylneuraminic acid. It can be synthesized by reacting 1,2,3-¹³C3]cytidine with sodium hydroxide and acetic anhydride in methanol. It is a carbohydrate that can be found in many plants and animals. This compound has been shown to inhibit glycosylation and methylation reactions. N-Acetyl-D-[1,2,3-¹³C3]neuraminic acid is also a monosaccharide that belongs to the group of sugars. Due to its high purity and availability, this substance can be used as a substitute for sialic acid in research experiments.Fórmula:C3C8H19NO9Pureza:Min. 95%Cor e Forma:PowderPeso molecular:312.25 g/mol6-Phospho-D-glucono-1,5-lactone
CAS:6-Phospho-D-glucono-1,5-lactone is a metabolite of D-gluconic acid that is formed by the action of a phosphoglucoisomerase. 6PGL has been shown to inhibit the growth of colorectal adenocarcinoma cells and to be effective against infectious diseases such as malaria. It is also involved in energy metabolism and cell division in plants. 6PGL may also have anticancer effects, as it inhibits prostate cancer cells and induces apoptosis through activation of epidermal growth factor receptor (EGFR) and inhibition of EGFR tyrosine kinase activity. It has been shown to act on redox potential, enzyme activities, and oxidative injury in liver cells.Fórmula:C6H11O9PPureza:Min. 95%Peso molecular:258.12 g/mol2,3,6,2',3',4',6'-Hepta-O-acetyl-b-lactosyl azide
CAS:2,3,6,2',3',4',6'-Hepta-O-acetyl-b-lactosyl azide is a custom synthesis of a carbohydrate that has been modified by the addition of acetyl groups to one end and the attachment of an azide group to the other. The synthesis of this compound has been completed in high purity and is available for purchase. This compound is a complex carbohydrate that is a sugar that can be modified by fluorination. It is also an oligosaccharide or polysaccharide with saccharide units.Fórmula:C26H35N3O17Pureza:Min. 95%Cor e Forma:PowderPeso molecular:661.57 g/mol2,3,4,6-Tetra-O-acetyl-a-D-mannopyranosyl bromide - stabilised with 2% CaCO3
CAS:Donor for Koenigs-Knorr type mannosylation and other anomeric substitutions
Fórmula:C14H19BrO9Pureza:Min. 95%Cor e Forma:Yellow PowderPeso molecular:411.2 g/mol2,3,4-Tri-O-benzyl-D-glucuronide methyl ester
2,3,4-Tri-O-benzyl-D-glucuronide methyl ester is an organic compound that is structurally classified as a saccharide. It can be used as an intermediate in the synthesis of oligosaccharides and glycosylated proteins. This product has been modified with Click chemistry, which is a method for modifying chemical structures with a simple reaction between two groups. The modification is stable in acidic conditions and can be removed by treatment with base. 2,3,4-Tri-O-benzyl-D-glucuronide methyl ester also contains fluorine atoms that have been introduced during the synthetic process.Fórmula:C28H30O7Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:478.53 g/molN-Benzyl-3,5-dideoxy-3,5-imino-1,2-O-isopropylidene-a-D-gluco(b-L-ido)furanose
N-Benzyl-3,5-dideoxy-3,5-imino-1,2-O-isopropylidene-a-D-gluco(b-L-ido)furanose is a methylated saccharide that is used in the synthesis of complex carbohydrates. This synthetic compound is classified as a sugar and can be modified with a variety of chemical reactions. The carbonyl group on the C6 position can be fluorinated to produce N-(2,4,6'-trifluoroacetyl)-benzyl--3,5-dideoxy--3,5--imino--1,2--O--isopropylidene--a-(D)--gluco(b)--L--ido)furanose. This compound has CAS Number 58424–52–0 and is available for custom synthesis.Pureza:Min. 95%
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