Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 837 produtos de "Antifúngicos"
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Isoconazole
CAS:<p>Isoconazole is an azole antifungal compound with a mode of action that inhibits ergosterol synthesis, disrupting fungal cell membranes. It is used for treating fungal infections of the skin and nails.</p>Fórmula:C18H14Cl4N2OPureza:Min. 95%Cor e Forma:White PowderPeso molecular:416.13 g/molAlbendazole
CAS:<p>Anthelmintic; inhibitor of tubulin polymerization</p>Fórmula:C12H15N3O2SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:265.33 g/molCaspofungin acetate - Bio-X ™
CAS:Produto Controlado<p>Caspofungin is an echinocandin that belongs to the class of antifungal agents. It is used to treat Aspergillus and Candida infections. It works by inhibiting the synthesis of beta-(1,3)-D-glucan, an essential component of the cell wall of Aspergillus species and Candida species.</p>Fórmula:C52H88N10O15·2C2H4O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:1,213.42 g/molLiranaftate
CAS:<p>Inhibitor of squalene epoxidase</p>Fórmula:C18H20N2O2SPureza:Min. 95%Cor e Forma:PowderPeso molecular:328.43 g/molVoriconazole - Bio-X ™
CAS:<p>Voriconazole is a synthetic, lipophilic molecule that is used in the treatment of fungal infections. Voriconazole binds to ergosterol which is the major sterol in the cell wall of fungi and inhibits its synthesis, leading to cell death. This drug binds to the enzyme 14α-demethylase allowing the conversion of lanosterol into ergosterol. As a result, this binding leads to the inhibition of ergosterol synthesis, as well as other sterols that are necessary for fungal growth (e.g., squalene).</p>Fórmula:C16H14F3N5OPureza:Min. 95%Cor e Forma:PowderPeso molecular:349.31 g/molTolnaftate
CAS:<p>Tolnaftate is a thiocarbamate antifungal agent with action on fungal cell membrane disruption and is used for treating fungal infections like athlete's foot, jock itch, and ringworm.</p>Fórmula:C19H17NOSPureza:Min. 95%Cor e Forma:PowderPeso molecular:307.41 g/molTerbinafine hydrochloride
CAS:<p>Activator of the two-pore domain potassium channel TASK3</p>Fórmula:C21H26ClNPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:327.89 g/molItraconazole - Bio-X ™
CAS:<p>Itraconazole is an anti-fungal drug that inhibits the synthesis of ergosterol, a component of the fungal cell membrane. Itraconazole is in a class of antifungals called triazoles. The drug binds to ergosterol in the fungal cell membrane and prevents it from being inserted into the membrane. This decreases the permeability of the plasma membrane, causing leakage of cellular contents. Additionally, it has been shown to have a glucose-lowering effect in the treatment of acute leukaemia and may be used for research in aiding to diagnose hematopoietic stem cell or leukaemia.</p>Fórmula:C35H38Cl2N8O4Pureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:705.63 g/molPosaconazole - Form I
CAS:<p>Posaconazole is an antifungal agent that inhibits the 14-alpha demethylase enzyme which is responsible for the synthesis of the fungal cell wall component, ergosterol. This demethylase enzyme synthesizes ergosterol through converting lanosterol to ergosterol. Therefore Posaconazole prevents the formation of fungal cell walls with the appropriate membrane permeability thus leading to fungal cell lysis. Posaconazole can be used as an antifungal drug to treat opportunistic fungal infections in immunocompromised individuals such as HIV patients. Moreover it is shown to inflict its inhibitory activity against common pathogenic fungus such as Candida and Aspergillus species but also Mucorales and some Fusarium species, which are less common.</p>Fórmula:C37H42F2N8O4Pureza:Min. 95%Peso molecular:700.78 g/mol2-Methyl-4-isothiazolin-3-one - 50% aqueous solution
CAS:Produto Controlado<p>2-Methyl-4-isothiazolin-3-one or MIT is a powerful antimicrobial and antifungal agent which is widely used in personal care products. It is also used in industrial applications as a preservative and antifouling agent.</p>Fórmula:C4H5NOSPureza:(%) Reported (%)Cor e Forma:Colorless Clear LiquidPeso molecular:115.15 g/molGriseofulvin - Bio-X ™
CAS:<p>Griseofulvin is an antifungal drug used to treat several types of dermatophytosis (ringworm). This includes fungal infections of the nails, scalp and the skin when antifungal creams have not worked. It is suggested that it prevents nuclear acid production and fungal cell mitosis. Additionally, through binding to alpha and beta tubulin, it interferes with the function of the spindle and cytoplasmic microtubules.</p>Fórmula:C17H17ClO6Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:352.77 g/molFR 901379 sodium
CAS:<p>Impurity of Micafungin; anti-fungal</p>Fórmula:C51H81N8O21S·NaPureza:Min. 95%Cor e Forma:PowderPeso molecular:1,197.29 g/molEfinaconazole
CAS:<p>Efinaconazole is a triazole antifungal agent with action on fungal 14α-demethylase to inhibit ergosterol synthesis and is used for treating onychomycosis (fungal nail infections).</p>Fórmula:C18H22F2N4OPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:348.39 g/molFluconazole - Bio-X ™
CAS:<p>Fluconazole is an antifungal drug used to treat a wide range of fungal infections. Fluconazole is a cytochrome demethylase system inhibitor that acts by interfering with β-glucan biosynthesis. It has been shown to be effective in treating candidemia, a life-threatening form of candidiasis caused by the fungus Candida albicans. Fluconazole seems to be more effective than amphotericin B in treating some isolates of C. albicans, making it a valuable tool in the fight against this deadly fungal infection, although due to the increase of antimicrobial resistance, fluconazole has been studied in combination with other drugs (e.g. farnesol).</p>Fórmula:C13H12F2N6OPureza:(%) Min. 95%Cor e Forma:PowderPeso molecular:306.27 g/mol2-Methyl-4-isothiazolin-3-one HCl
CAS:Produto Controlado<p>2-Methyl-4-isothiazolin-3-one HCl , also known as MIT hydrochloride is often used as a preservative in personal care products and other industrial applications. The product has shown to act as an antimicrobial and antifungal agent.</p>Fórmula:C4H5NOS·HClPureza:Min. 95%Cor e Forma:White Slightly Yellow PowderPeso molecular:151.62 g/molFilipin
CAS:<p>Filipin is a polyene macrolide antifungal agent with action on cholesterol in cell membranes and is used for histochemical staining and research on cholesterol metabolism.</p>Pureza:Min. 97 Area-%Cor e Forma:Yellow PowderClotrimazole
CAS:<p>Clotrimazole is an azole antifungal medication with action on fungal cell membrane disruption and is used for treating fungal infections like athlete's foot, ringworm, and vaginal yeast infections.</p>Fórmula:C22H17ClN2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:344.84 g/molIsavuconazole
CAS:<p>Anti-fungal; lanosterol 14α-demethylase inhibitor</p>Fórmula:C22H17F2N5OSPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:437.47 g/molAmphotericin A
CAS:<p>Amphotericin A is a polyene macrolide antibiotic, which is derived primarily from the soil bacterium *Streptomyces nodosus*. This compound functions by binding to ergosterol, an essential component of fungal cell membranes. This binding creates pores in the membrane, increasing its permeability and ultimately leading to cell death. Unlike its more widely used counterpart Amphotericin B, Amphotericin A is less frequently utilized but is critical in the study and understanding of antifungal activity.</p>Fórmula:C47H75NO17Pureza:Min. 95%Peso molecular:926.09 g/mol
