CAS 126-07-8

Griseofulvina

Descrição:

Griseofulvina é um medicamento antifúngico usado principalmente para tratar infecções por dermatófitos, particularmente aquelas que afetam a pele, cabelo e unhas. É derivado do mofo Penicillium griseofulvum e funciona inibindo a mitose das células fúngicas, impedindo assim o crescimento e a reprodução de fungos. Griseofulvina é caracterizado por sua estrutura cristalina e é tipicamente administrado por via oral. É pouco solúvel em água, mas mais solúvel em solventes orgânicos, o que influencia sua absorção e biodisponibilidade. A substância é conhecida por sua meia-vida relativamente longa, permitindo a dosagem uma vez ao dia em muitos casos. Efeitos colaterais comuns podem incluir distúrbios gastrointestinais, dor de cabeça e reações alérgicas potenciais. Griseofulvina é contraindicado em certas populações, como indivíduos grávidas, devido a possíveis efeitos teratogênicos. Sua eficácia é frequentemente avaliada por meio de avaliação clínica e testes laboratoriais para confirmar a presença de espécies fúngicas suscetíveis. No geral, Griseofulvina continua sendo uma opção terapêutica significativa no manejo de infecções fúngicas específicas.

Fórmula: C₁₇H₁₇ClO₆

InChI: InChI=1/C17H19ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h7-8,12H,5-6H2,1-4H3/t8-,12?,17+/m1/s1

Chave InChI: InChIKey=DDUHZTYCFQRHIY-RBHXEPJQSA-N

SMILES: O=C1[C@@]2(OC=3C1=C(OC)C=C(OC)C3Cl)C(OC)=CC(=O)C[C@H]2C

Sinónimos:

• (1′S,6′R)-7-Chloro-2′,4,6-trimethoxy-6′-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
• (2R,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• (2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohexane]-3,4'-dione
• (2S,6'S)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• 7-Chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• 7-Chloro-2',4,6-trimethoxy-6'β-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• 7-Chloro-2′,4,6-trimethoxy-6′β-methylspiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione
• 7-chloro-2',4,6-trimethoxy-6'-methyl-3H,4'H-spiro[1-benzofuran-2,1'-cyclohex[2]ene]-3,4'-dione
• Amudane
• Curling factor
• Fulcin
• Fulvicin
• Fulvicin Bolus
• Fulvicin P/G
• Fulvicin U/F
• Fulvidex
• Fulvina
• Fulvinil
• Fulvistatin
• Gricin
• Grifulin
• Grifulvin
• Grifulvin V
• Gris-PEG
• Grisactin
• Grisefulin
• Griseofulvin Powder
• Griseofulvina
• Griseofulvine
• Griseovin
• Grisofulvin
• Grisovin
• Grisovin FP
• Grysio
• Idifulvin
• Lamoryl
• Likuden
• Neo-Fulcin
• Polygris
• Poncyl
• Poncyl FP
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S,6'R)-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'S-trans)-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione, 7-chloro-2',4,6-trimethoxy-6'β-methyl-
• Spiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione,7-chloro-2',4,6-trimethoxy-6'-methyl-, (1'R-trans)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1′S,6′R)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′-methyl-, (1′S-trans)-
• Spiro[benzofuran-2(3H),1′-[2]cyclohexene]-3,4′-dione, 7-chloro-2′,4,6-trimethoxy-6′β-methyl-
• Spirofulvin
• Sporostatin
• Xuanjing
• (+)-Griseofulvin
• 7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYL-, (1'S-TRANS)-SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE
• (2s-trans)-7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3h),1’-[2]cy
• (2S)-TRANS-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2[3H],1'-[2]CYCLOHEXENE)-3,4'-DIONE
• Delmofulvina
• (2s-trans)-xy-6’-methyl
• 7-chloro-4,6,2’-trimethoxy-6’-methylgris-2’-en-3,4’-dione
• curlingfactor
• 7-Chloro-2',4,6-trimethoxy-6'beta-methylspiro[benzofuran-2(3H),1'-[2]cyclohexene]-3,4'-dione
• [2S-TRANS]-7-CHLORO-2,4,6-TRIMETHOXY-6'-METHYLSPIRO[BENZOFURAN-2(3H), 1'(2)-CYCLOHEXANE]-3,4'-DIONE
• (+)-griseofulvi
• -6’-beta-methyl-
• 7-Chloro-4,6,2'-trimethoxy-6'-methylgris-2'-en-3,4'-dione
• 2’-en-4’-one)
• clohexene]-3,4’-dione
• 6-dimethoxycoumaran-3-one-2-spiro-1’-(2’-methoxy-6’-methylcyclohex-7-chloro-

(+)-Griseofulvin

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: >95.0%(HPLC)(qNMR)

Cor e Forma: White to Almost white powder to crystal

Peso molecular: 352.77

Ref: 3B-G0384

(+)-Griseofulvin, 97%

CAS: 126-07-8

Griseofulvin is an antifungal drug. It is used both in animal and in humans, to treat ringworm infections of the skin and nails. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy br

Fórmula: C₁₇H₁₉ClO₆

Pureza: 97%

Cor e Forma: White, Powder

Peso molecular: 354.78

Ref: 02-B23521

Griseofulvin

CAS: 126-07-8

Cor e Forma: Neat

Ref: 61-FOR0582.00

Griseofulvin

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: 99.11%

Cor e Forma: Brownish. Powder

Peso molecular: 353.0

Ref: 8R-CL0363

GRISEOFULVIN FOR SYSTEM SUITABILITY CRS

CAS: 126-07-8

GRISEOFULVIN FOR SYSTEM SUITABILITY CRS

Ref: 41-Y0002044

GRISEOFULVIN RS

CAS: 126-07-8

GRISEOFULVIN RS

Fórmula: C₁₇H₁₇ClO₆

Peso molecular: 352.7663

Ref: 41-ICRS0322

GRISEOFULVIN FOR LC ASSAY AND IDENTIFICATION CRS

CAS: 126-07-8

GRISEOFULVIN FOR LC ASSAY AND IDENTIFICATION CRS

Cor e Forma: Added

Ref: 41-Y0002046

Griseofulvin Permeability Diameter

CAS: 126-07-8

Antibiotics nesoi

Fórmula: C₁₇H₁₇ClO₆

Cor e Forma: White Off-White Powder

Peso molecular: 352.77

Ref: 45-1299200

Griseofulvin

CAS: 126-07-8

Antibiotics nesoi

Fórmula: C₁₇H₁₇ClO₆

Cor e Forma: White Cream Powder

Peso molecular: 352.07137

Ref: 45-1299007

(2S,6'R)-7-chloro-2',4,6-trimethoxy-6'-methyl-3H-spiro[1-benzofuran-2,1'-cyclohexan]-2'-ene-3,4'-dione

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: 95%

Cor e Forma: Solid

Peso molecular: 352.7663

Ref: IN-DA0032AV

Griseofulvin

CAS: 126-07-8

Griseofulvin (Fulvicin) is an antifungal agent used in the treatment of TINEA infections.

Fórmula: C₁₇H₁₇ClO₆

Pureza: 97.06% - 98.12%

Cor e Forma: Stout Octahedra Or Rhombs From Benzene

Peso molecular: 352.77

Ref: TM-T1382

Griseofulvin-13C-d3

CAS: 126-07-8

Fórmula: C₁₆₁₃CH₁₄D₃ClO₆

Cor e Forma: White To Off-White Solid

Peso molecular: 356.78

Ref: 4Z-G-088

Griseofulvin

CAS: 126-07-8

Griseofulvin

Fórmula: C₁₇H₁₇ClO₆

Pureza: ≥95%

Peso molecular: 352.77

Ref: 54-BUP18502

Griseofulvin

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Cor e Forma: White To Off-White Solid

Peso molecular: 352.77

Ref: 4Z-G-082

(+)-Griseofulvin

CAS: 126-07-8

(+)-Griseofulvin

Fórmula: C₁₇H₁₇ClO₆

Pureza: 98%

Cor e Forma: Solid

Peso molecular: 352.77

Ref: 54-OR1029322

Griseofulvin

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: 97.0 - 102.0 % (dried basis)

Cor e Forma: White or off-white powder

Peso molecular: 352.77

Ref: 7W-GA6599

Griseofulvin, EP grade

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Pureza: ≤ 0.75%

Cor e Forma: White or pale yellow powder

Peso molecular: 352.77

Ref: 7W-GA3498

Griseofulvin

Produto Controlado

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Cor e Forma: Off-White

Peso molecular: 352.77

Ref: 86-MM0582.00

Griseofulvin

Produto Controlado

CAS: 126-07-8

Fórmula: C₁₇H₁₇ClO₆

Cor e Forma: Neat

Peso molecular: 352.77

Ref: 04-C14056500

Griseofulvin (Standard)

CAS: 126-07-8

Griseofulvin (Standard) is the standard substance of Griseofulvin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Griseofulvin (Fulvicin) is an antifungal agent used in the treatment of TINEA infections.

Fórmula: C₁₇H₁₇ClO₆

Peso molecular: 352.77

Ref: TM-TMSM-1289