Antifúngicos
Os antifúngicos são compostos especificamente projetados para interromper, prevenir e eliminar o crescimento de fungos. Nesta categoria, você encontrará uma ampla variedade de agentes antifúngicos essenciais para pesquisa e aplicações terapêuticas. Esses compostos são cruciais no tratamento de infecções fúngicas e na prevenção de sua recorrência, tornando-os ferramentas vitais tanto em ambientes médicos quanto agrícolas. Pesquisadores e profissionais de saúde podem explorar inúmeros antifúngicos para entender seus mecanismos, otimizar sua eficácia e desenvolver novos tratamentos para combater cepas fúngicas resistentes. A extensa seleção de antifúngicos apoia os avanços contínuos na pesquisa sobre fungos e no desenvolvimento de terapias antifúngicas eficazes.
Foram encontrados 906 produtos de "Antifúngicos"
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(R)-3-hydroxy Myristic Acid
CAS:Lipopolysaccharides (LPS) are components of the cell walls of Gram-negative bacteria.Fórmula:C14H28O3Pureza:≥98%Cor e Forma:White PowderPeso molecular:244.37Laccase-IN-1
Laccase-IN-1 (compound 4b) is an orally active laccase inhibitor, demonstrating an IC50 of 11.3 μM.Fórmula:C16H19FN2O3Cor e Forma:SolidPeso molecular:306.33Ophiobolin B
CAS:Ophiobolin B is a sesterterpene Helminthosporium oryzae metabolite, inhibits proton extrusion from maize coleoptiles.Fórmula:C25H38O4Pureza:98%Cor e Forma:SolidPeso molecular:402.57Kievitone
CAS:Kievitone, an isoflavanone from Phaseolus vulgaris, has antifungal and antitumor properties.Fórmula:C20H20O6Cor e Forma:SolidPeso molecular:356.37Paclobutrazol
CAS:Paclobutrazol ((R,R)-paclobutrazol) is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins.1,2It also has
Fórmula:C15H20ClN3OPureza:99.23%Cor e Forma:Off-White To Beige SolidPeso molecular:293.79Amphotericin B methyl ester
CAS:Amphotericin B methyl ester: a cholesterol-binding antifungal derivative of Amphotericin B; inhibits HIV-1.Fórmula:C48H75NO17Pureza:98%Cor e Forma:SolidPeso molecular:938.118Ratjadon
CAS:Ratjadon is an antifungal compound isolated from Sorangium cellulosum.Fórmula:C28H40O5Pureza:98%Cor e Forma:SolidPeso molecular:456.61Antifungal agent 108
Antifungalagent 108 (compound 14d) is an original imidazo[1,2-b]pyridazine derivative that exhibits potent antifungal activity against Madurella mycetomatis (MM55 strain) with an IC50 of 0.9 μM. The compound shows an IC50 of 14.3 μM for cell viability in NIH-3T3 mouse fibroblasts.Cor e Forma:Odour SolidOxadixyl
CAS:Oxadixyl is used as a fungicide.Fórmula:C14H18N2O4Pureza:98%Cor e Forma:SolidPeso molecular:278.30α-Guaiene
CAS:α-Guaiene, a sesquiterpene identified in P. cablin, showcases its presence within this species.Fórmula:C15H24Cor e Forma:SolidPeso molecular:204.35CYP51-IN-24
CYP51-IN-24 (Compound 22) is an inhibitor of Sterol 14α-Demethylase (CYP51). It exhibits potent inhibitory activity against both wild-type and resistant fungi. By binding to the fungal CYP51 enzyme, CYP51-IN-24 prevents the biosynthesis of ergosterol. This compound is applicable in the research and development of treatments for drug-resistant fungal infections.Cor e Forma:Odour SolidIturin A
CAS:Iturin A: antifungal compound targeting cell membranes, forms ion pores in yeast/fungi.Cor e Forma:SolidAmphotericin B
CAS:Fórmula:C47H73NO17Pureza:≥ 750μg/mg (C47H73NO17, dried basis)Cor e Forma:Yellow to dark yellow or orange powderPeso molecular:924.10Latrunculin B
CAS:Latrunculin B: alkaloid, inhibits actin polymerization, antifungal, antiprotozoal, modulates heart rhythm, studied in glaucoma.Fórmula:C20H29NO5SPureza:98%Cor e Forma:SolidPeso molecular:395.51Antibacterial agent 218
Antibacterialagent 218 (compound d28) is an orally active inhibitor of sterol 24-C-methyltransferase with an IC50 value of 0.273 μM. It also displays antifungal activity against Candida albicans SC5314, with an IC50 of 0.25 μg/mL.Fórmula:C30H24N4OSPeso molecular:488.16708CYP51-IN-26
CYP51-IN-26 is a CYP51 inhibitor with an IC50 value of approximately 0.40 μM. It effectively eradicates Candida auris biofilms and significantly enhances cellular uptake in accumulation studies. Moreover, CYP51-IN-26 provides protection against Candida auris infection in both G. mellonella and D. melanogaster models. It is applicable for research on fungal infections.Cor e Forma:Odour SolidAntifungal agent 62
Compound 3a (Antifungal agent 62) exhibits potent fungicidal properties, particularly against Fusarium oxysporum f.sp.Cor e Forma:Odour SolidAntifungal agent 84
CAS:Antifungal Antibacterial agent 84 targets CNB1 to thwart C. albicans biofilm.Fórmula:C25H19BrClFN6OCor e Forma:SolidPeso molecular:553.81Succinate dehydrogenase-IN-9
Succinate dehydrogenase-IN-9 (Compound Iik) is an inhibitor of succinate dehydrogenase with an IC50 of 3.6 μM. It demonstrates strong inhibitory activity against various fungi, such as S. sclerotiorum, with an EC50 of 1.14 μg/mL. Additionally, Succinate dehydrogenase-IN-9 enhances nitrate reductase activity, promoting plant growth.Fórmula:C24H29F2N3O5Cor e Forma:SolidPeso molecular:477.20753L-4-Oxalysine hydrochloride
CAS:L-4-Oxalysine hydrochloride has shown antitumor activities, is a natural product isolated from the culture media of Streptomyces roseovirdofuscus in China.Fórmula:C5H13ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:184.62Tetrahydroechinocandin B
CAS:Tetrahydroechinocandin B is a cyclic hexapeptide containing a fatty acyl side chain. It also inhibits 1,3-beta-D-glucan synthesis.Fórmula:C52H85N7O16Pureza:98%Cor e Forma:SolidPeso molecular:1064.273-hydroxy Myristic Acid methyl ester
CAS:3-hydroxy Myristic acid methyl ester found in Eucalyptus, combats M. tuberculosis, non-toxic to Vero cells, and in wild strawberry aroma, not in cultivated.Fórmula:C15H30O3Cor e Forma:SolidPeso molecular:258.402MK-5204
CAS:MK-5204 is an orally active β-1,3-glucan synthesis inhibitor.Fórmula:C40H65N5O5Cor e Forma:SolidPeso molecular:695.99Picarbutrazox
CAS:Picarbutrazox: potent pesticide/fungicide for corn/soybean against Pythium/Phytophthora.Fórmula:C20H23N7O3Cor e Forma:SolidPeso molecular:409.44ent-Heronamide C
Ent-Heronamide C possesses antifungal properties and is utilized as a probe for analyzing the mode of action of heronamide C [1].Fórmula:C29H41NO3Cor e Forma:SolidPeso molecular:451.64FR179642
CAS:FR179642 is a key intermediate for making Micafungin, a drug from the echinocandin class.Fórmula:C35H52N8O20SCor e Forma:SolidPeso molecular:936.9TPS1-IN-1
TPS1-IN-1 (Compound O1) is a potent and broad-spectrum inhibitor of TPS1. It exhibits IC50 values of 14.73 μM for MoTPS1 (Magnaporthe oryzae TPS1) and 59.99 μM for BcTPS1 (Botrytis cinerea TPS1). TPS1-IN-1 exerts its broad-spectrum fungicidal effects by disrupting spore germination, appressorium formation, and turgor pressure accumulation in fungi. With good safety profiles, TPS1-IN-1 has potential as a candidate for novel fungicide development.Fórmula:C19H26F3N5O4SCor e Forma:SolidPeso molecular:477.505-epi-Jinkoheremol
CAS:5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin.Fórmula:C15H26OCor e Forma:SolidPeso molecular:222.372Antifungal agent 47
Compound 3b is a potent broad-spectrum fungicide with strong respiratory and ATP synthesis inhibition.Fórmula:C39H38BrClNO2PCor e Forma:SolidPeso molecular:699.06(−)-Voacangarine
CAS:(–)-Voacangarine, an indole alkaloid isolated from V. africana, exhibits cytotoxicity towards various cell lines including HepG2, A375, MDA-MB-231, SH-SY5Y, and CT26 with IC50 values of 20 µg/ml. Additionally, it demonstrates cytostatic effects on wild-type S. cerevisiae and is cytotoxic to Δrad3-e5 and Δrad6-1 mutant strains of S. cerevisiae, which have defects in DNA strand break repair and the mutagenic repair pathway, respectively.Fórmula:C22H28N2O4Cor e Forma:SolidPeso molecular:384.471,3,6-Trihydroxy-5-methoxyxanthone
1,3,6-Trihydroxy-5-methoxyxanthone is a useful organic compound for research related to life sciences and the catalog number is T124882.Fórmula:C14H10O6Cor e Forma:SolidPeso molecular:274.228Diclobutrazol
CAS:Diclobutrazol: potent systemic fungicide against rusts, mildews, and crop diseases.Fórmula:C15H19Cl2N3OCor e Forma:SolidPeso molecular:328.24Methyl 3-(1H-indol-3-yl)propanoate
CAS:Methyl 3-(1H-indol-3-yl)propanoate has antifungal activity and is both an analogue of brassinin and a weaker antidote.Fórmula:C12H13NO2Pureza:99.88%Cor e Forma:SolidPeso molecular:203.24Concanamycin C
CAS:Concanamycin C, a natural macrolide antibiotic, was initially isolated from Streptomyces and identified as an inhibitor of T-cell proliferation in response to concanavalin A (1,2). It exhibits cytotoxicity to fungi, including yeasts, by inhibiting vacuolar-type ATPases (3,4).Fórmula:C45H74O13Cor e Forma:SolidPeso molecular:823.1Picoxystrobin
CAS:Picoxystrobin, a strobilurin fungicide, halts mitochondrial respiration in plants by blocking electron transfer.Fórmula:C18H16F3NO4Cor e Forma:SolidPeso molecular:367.32Janthitrem F
CAS:Janthitrem F, a naphthopyran also known as 10-O-acetyljanthitrem E, is a tremorgenic mycotoxin produced by Penicillium janthinellum.Fórmula:C39H51NO7Cor e Forma:SolidPeso molecular:645.82Dermaseptin-S1
CAS:Dermaseptin-S1, an antimicrobial peptide sourced from frog skin, exhibits efficacy against filamentous fungi [1].Fórmula:C152H257N43O44S2Cor e Forma:SolidPeso molecular:3455.06LW3
CAS:LW3 is an effective broad-spectrum antifungal compound.Fórmula:C17H12F3N3OPureza:99.86%Cor e Forma:SoildPeso molecular:331.29Liranaftate
CAS:Fórmula:C18H20N2O2SPureza:≥ 98.0%Cor e Forma:White to almost white powder or crystalsPeso molecular:328.43Endo-1,3-β-glucanase
CAS:Endo-1,3-β-glucanase (Lyticase) is a glucanase from fungi and Chlamydomonas reinhardtii that displays lytic activity on fungal cells.Cor e Forma:SolidSclerotiorin
CAS:Sclerotiorin, from Penicillium, inhibits soybean lipoxygenase-1 (IC50: 4.2 μM) and other proteins, antagonizes endothelin receptors.Fórmula:C21H23ClO5Cor e Forma:SolidPeso molecular:390.86Deacetylsclerotiorin, (-)-
CAS:deacetylsclerotiorin is a new chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550.Fórmula:C19H21ClO4Cor e Forma:SolidPeso molecular:348.82Frequentin
CAS:Frequentin, an antibiotic from P. frequentans, combats bacteria and fungi; MICs: 200 µg/ml for B. subtilis, 300 for S. aureus.Fórmula:C14H20O4Cor e Forma:SolidPeso molecular:252.31Metalaxyl-M
CAS:Metalaxyl-M, an (R)-enantiomer fungicide, inhibits fungi protein/RNA synthesis, used in Oomycota research.Fórmula:C15H21NO4Cor e Forma:SolidPeso molecular:279.33Dermaseptin-S5
CAS:Dermaseptin-S5 is an antimicrobial peptide sourced from frog skin that exhibits activity against filamentous fungi [1].Fórmula:C128H223N37O35Cor e Forma:SolidPeso molecular:2840.37SDH-IN-7
SDH-IN-7 (compound G28) is a potent inhibitor of succinate dehydrogenase (SDH), exhibiting an IC50 value of 26 nM against porcine SDH and possesses fungicidalFórmula:C18H15Cl3F3N3OCor e Forma:SolidPeso molecular:452.69Asperfuran
CAS:Asperfuran is a useful organic compound for research related to life sciences. The catalog number is T125958 and the CAS number is 138331-36-9.Fórmula:C13H14O3Cor e Forma:SolidPeso molecular:218.252Pervicoside B
CAS:Pervicoside B is a triterpene glycoside.Fórmula:C54H86NaO25SPureza:98%Cor e Forma:SolidPeso molecular:1190.31Fenticonazole nitrate
CAS:Fórmula:C24H20Cl2N2OS·HNO3Pureza:(Titration) 98.0 - 102.0 % (anhydrous basis)Cor e Forma:White or almost white powderPeso molecular:518.41
