Antimicrobianos

STAADIUMTM GalactoZide II is a targeted inhibitor for β-galactosidase producing bacteria. The antibacterial activity of STAADIUMTM GalactoZide II is triggered by the enzyme β-galactosidase which is produced by E.coli (EHEC), thermophilic lactic acid bacteria, and other coliform bacteria. STAADIUMTM GalactoZide II can help to selectively inhibit the growth of E. coli in complex bacterial cultures and canbe used in microbiome studies, food control, environmental safety, hygiene, and clinical diagnostics. STAADIUMTM GalactoZide II is not compatible with some experimental conditions, e.g. pH indicators such as neutral red, indigo stains, and possibly H2S staining. STAADIUMTM GalactoZide II can be added as an enzyme-specific selective supplement to agar plates and as an enrichment agent to broth culture.

Flubendazole is a benzimidazole anthelmintic with action on microtubule formation in parasites and is used for treating intestinal worms in humans and animals.

4-Epichlortetracycline is a metabolite of chlortetracycline, which is derived from the Streptomyces genus of bacteria. It is structurally related to tetracycline antibiotics but differs specifically in its epimerization at the fourth position. This alteration results in a product with significantly reduced antibacterial activity compared to its parent compound. The mechanism of action primarily involves ribosomal binding, inhibiting protein synthesis in susceptible bacteria; however, the epimerization here compromises this efficacy.

Herbicidin K is a naturally derived herbicide, known for its biological origin from microbial fermentation processes. It is primarily sourced from certain strains of Streptomyces, a genus of Gram-positive bacteria notable for their diverse secondary metabolites. The mode of action of Herbicidin K involves the inhibition of key enzymatic pathways within target plants, leading to the disruption of cellular functions and ultimately plant death. This selectivity is particularly effective against broadleaf weeds, providing a targeted approach to weed management.

Taniborbactam is a groundbreaking boronic acid-based beta-lactamase inhibitor, which is a chemically synthesized compound designed to enhance the efficacy of beta-lactam antibiotics. Its mode of action involves the irreversible inhibition of a wide range of beta-lactamase enzymes, including both serine and metallo-beta-lactamases, which are responsible for the antibiotic resistance in many bacterial pathogens. By binding to the active sites of these enzymes, Taniborbactam prevents them from hydrolyzing the beta-lactam ring, thus restoring the antibacterial activity of beta-lactam antibiotics.

Tenofovir diphosphate is an antiviral compound, which is a key active metabolite derived from the prodrugs tenofovir disoproxil fumarate and tenofovir alafenamide, both originating from chemical synthesis. Its mode of action involves inhibiting the activity of HIV-1 reverse transcriptase by competing with the natural substrate, deoxyadenosine 5’-triphosphate, and causing chain termination after incorporation into viral DNA. This mechanism effectively prevents the replication of retroviral DNA, thus halting the progression of the infection.

Perfluorodecanephosphonic acid is a fluorinated organic compound, which is synthesized through the controlled polymerization of fluorinated precursors. It is characterized by its unique perfluorinated alkyl chain and a phosphonic acid group, providing a distinctive combination of hydrophobic and functional properties. Its mode of action involves the strong adsorption onto surfaces through the phosphonic acid moiety, allowing the formation of highly stable self-assembled monolayers (SAMs).

Dicloxacillin is a penicillin antibiotic that is used to treat bacterial infections of the gastrointestinal tract, skin, and urinary tract. It binds to the penicillin-binding proteins in bacterial cell walls by competitive inhibition. Dicloxacillin inhibits bacterial growth by binding to the enzyme cell wall synthesis that is required for cell wall biosynthesis, inhibiting protein synthesis and cell division. This drug also has a toxic effect on respiratory system cells, which may be due to its ability to induce apoptosis. Dicloxacillin sodium salt is available as tablets for oral administration or as an intravenous solution for injection. It can interact with other drugs, such as benzalkonium chloride and matrix effect; it also has analytical methods such as chromatographic analysis and rate constant.

Phleomycin is an antibiotic, which is derived from the bacterium *Streptomyces verticillus*. Its mode of action involves binding to DNA and inducing breaks by generating free radicals in the presence of oxygen and ferrous ions, leading to cell death. Phleomycin is prominently used in molecular biology applications as a selective agent in the generation of stable transfectants. It is particularly effective in selecting for cells that have integrated vectors conferring resistance, such as the Sh ble gene used in yeast, plant, and mammalian cell systems. Due to its potent DNA-cleaving ability, Phleomycin is valuable in studies requiring stringent selection pressure. Researchers commonly utilize it in experiments focusing on genetic modification and cellular resistance development.

Butirosin disulfate is an aminoglycoside antibiotic, which is derived from a strain of *Bacillus circulans*. Its primary mode of action involves binding to the 30S subunit of the bacterial ribosome, leading to the inhibition of protein synthesis. This interaction results in the misreading of mRNA, ultimately causing bactericidal effects.

Mecillinam is a beta-lactam antibiotic specifically designed for use in culture media. It is derived from the amidinopenicillin family, featuring a unique ability to interfere with bacterial cell wall synthesis. Its mode of action involves inhibiting penicillin-binding protein 2 (PBP2), an essential enzyme for cell wall elongation and maintenance in Gram-negative bacteria. This targeted inhibition results in the formation of spherical cells and subsequent cell lysis.

Aminosidine is a nucleoside analogue that inhibits the HIV-1 reverse transcriptase and the integrase, which are enzymes involved in viral DNA synthesis. Aminosidine is active against Leishmania spp., but not against bacteria. Aminosidine has been shown to be effective in experimental models of human bowel disease and in patients with inflammatory bowel disease. It was also found to be active against wild-type strains of human immunodeficiency virus type 1, but not resistant mutants. The mechanism of action is the inhibition of cellular mitochondrial membrane potential.

Ganciclovir is an antiviral agent specifically designed for culture media use. It is a synthetic analogue of 2'-deoxy-guanosine, derived from nucleoside compounds, and operates primarily by inhibiting the replication of viral DNA. Its mode of action involves selective phosphorylation by viral kinases, which converts it into ganciclovir triphosphate, a potent inhibitor of viral DNA polymerase, ultimately preventing viral DNA synthesis.

Bentaluron is a synthetic fungicide, which is a chemical compound developed to combat fungal pathogens in agriculture. Its source originates from rigorous industrial chemical synthesis, ensuring efficacy and stability. The mode of action of Bentaluron involves disrupting essential biochemical pathways within fungal cells, specifically targeting and inhibiting enzymes critical for fungal growth and metabolism. This precise interference prevents the synthesis of vital cellular components, ultimately halting the proliferation of the fungus.

Please enquire for more information about Cephalexin hydrate, Antibiotic for Culture Media Use Only including the price, delivery time and more detailed product information at the technical inquiry form on this page

Abacavir sulfate is a pharmaceutical compound classified as a nucleoside reverse transcriptase inhibitor (NRTI), which is derived from synthetic sources. Its mode of action involves the inhibition of the reverse transcriptase enzyme, essential for the replication of HIV. By incorporating itself into the viral DNA chain during replication, Abacavir effectively halts the process, preventing further multiplication of the virus within the host cells.

This antiretroviral medication is primarily used in the management and treatment of human immunodeficiency virus (HIV-1) infections. Abacavir sulfate is a critical component in highly active antiretroviral therapy (HAART), contributing to the reduction of viral load, enhancing immune function, and improving the long-term clinical outcomes in patients living with HIV. Its application in combination therapies has been instrumental in transforming HIV from a fatal disease into a manageable chronic condition.