Protacs e Impurezas

RSS0680 is a protein kinase degrader that degrades a variety of kinases and can be …

PROTAC EED degrader-1 is a PROTAC targeting EED (pKD = 9.02), is a inhibitor of …

SIAIS178 is a potent and selective degrader of BCR-ABL based on PROTAC technology (IC50 of …

TL13-12 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.69 nM).

PROTAC EED degrader-2 is a PROTAC targeting EED (pKD of 9.27),is a inhibitor of polycomb …

PROTAC BET degrader-2 is a highly potent degrader of Bromodomain and Extra-Terminal (BET) proteins (IC50 …

ARCC-4: A VHL-recruiting, low-nanomolar (DC50=5nM) AR degrader; outshines enzalutamide; degrades AR mutants resistant to therapy.

dFKBP-1 is a potent and PROTAC-based FKBP12 degrader. dFKBP-1 incorporates the ligand SLF of FKBP12, …

PROTAC ER Degrader-4 is a PROATC degrader of estrogen receptor (ER)(IC50 of 0.8 nM).

BETd-246 is an inhibitor of second-generation and PROTAC-based BET bromodomain (BRD), show antitumor activity.

PROTAC CRBN Degrader-1: a compound with CRBN and VHL binding groups linked, serving as a …

PROTAC FLT-3 degrader 1 is a PROTAC FLT-3 degrader of internal tandem duplication (ITD)(IC50 0.6 …

PROTAC MDM2 Degrader-2: A potent MDM2-targeting compound with PROTAC tech for E3 ligase-mediated degradation.

PROTAC IRAK4 degrader-1 is a degrader of PROTAC interleukin-1 receptor-associated kinase 4 (IRAK4).

ARD-266: Potent VHL-based AR degrader; degrades AR in prostate cancer cells with DC50s of 0.2-1 …

PROTAC ERα Degrader-1 is a chemical compound.

PROTAC RIPK degrader-2 is a nonpeptidic PROTAC ,and potently targets serine-threonine kinase RIPK2 and has …

iRucaparib-AP6: a specific, non-trapping PARP1 degrader; inhibits the enzyme's activity and scaffolding.

PROTAC FAK degrader 1 is a selective and potent degrader of focal adhesion kinase (Fak) …

TL13-112 is a selective degrader of ALK-PROTAC and inhibits ALK activity (IC50: 0.14 nM).