Terpenóides

Tripdiolide is a bioactive diterpenoid, which is derived from the Chinese medicinal plant Tripterygium wilfordii, commonly known as Thunder God Vine. This compound exerts its effects through a complex mode of action, primarily involving the inhibition of nuclear factor kappa B (NF-kB) signaling pathways and the induction of apoptosis. Recent studies have also suggested its role in modulating the immune response by targeting specific cytokines and signaling pathways.

QS-21 is a saponin-based adjuvant, which is a compound used to enhance the body's immune response to an antigen. This product is derived from the bark of the Quillaja saponaria tree, commonly known as the soapbark tree, native to Chile. The mode of action of QS-21 involves stimulating the immune system by activating antigen-presenting cells, such as dendritic cells and macrophages, which in turn enhance both humoral and cellular immune responses.

Madecassic acid is a triterpenoid compound, which is a natural chemical constituent of Centella asiatica, commonly known as Gotu Kola. This source is a perennial herbaceous plant belonging to the Apiaceae family, widely distributed in tropical and subtropical countries. Madecassic acid acts primarily through its anti-inflammatory and antioxidant mechanisms. It modulates inflammatory responses by inhibiting the activation of NF-κB signaling pathways and reducing the production of pro-inflammatory cytokines. Additionally, it contributes to cellular protection by scavenging reactive oxygen species.

Muzigadial is a sesquiterpene dialdehyde, which is a type of natural product isolated from the plant Myristica ceylanica. This compound is characterized by its biogenically derived structural complexity that confers an array of bioactive properties. It operates primarily through its interaction with biological membranes and proteins, leading to disruptions in cellular processes and inhibition of microbial growth.

(-)-Secologanin is a monoterpenoid glycoside, which is a key intermediate in the biosynthesis of indole alkaloids, found primarily in plants such as those in the Apocynaceae and Rubiaceae families. It plays a crucial role in the natural production of complex alkaloids, forming the backbone for numerous pharmacologically active compounds, including quinine, camptothecin, and ajmalicine.

Lupeol acetate analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.