Canabinóides
Os canabinoides são uma classe de compostos químicos diversos derivados de ácidos graxos ou poliquetídeos que atuam sobre os receptores canabinoides nas células, alterando a liberação de neurotransmissores no cérebro. Encontrados principalmente em plantas de cannabis, canabinoides como THC e CBD são amplamente estudados por seus efeitos terapêuticos, incluindo alívio da dor, propriedades anti-inflamatórias e uso potencial em doenças neurodegenerativas. Na CymitQuimica, você encontrará uma ampla variedade de canabinoides para pesquisa em farmacologia, neurobiologia e química medicinal.
Foram encontrados 563 produtos para "Canabinóides".
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UCM710
CAS:UCM710 is a dual inhibitor of α/β hydrolase domain 6 (ABHD6) and fatty acid amide hydrolase (FAAH).Fórmula:C19H34O3Pureza:98%Cor e Forma:SolidPeso molecular:310.47(-)-CP 55940 (10 mg/mL in methanol)
CAS:Produto ControladoApplications CP 55,940 is a cannabinoid agonist which is considerably more potent than Δ9-THC in both behavioral tests and receptor binding assays. Displays high and roughly equal affinity for both central and peripheral cannabinoid receptors (Ki = 0.6 - 5.0 and 0.7 - 2.6 nM at CB1 and CB2 respectively; EC50 values are 0.2, 0.3 and 5 nM at CB1, CB2 and GRP55 respectively).Controlled substance. Synthetic Cannabinoids
References Wiley, et al.: Neuropharmacology, 34, 669 (1995); Griffin, et al.: J. Pharmacol. Exp. Ther., 285, 553 (1998); Thomas, et al.: J. Pharmacol. Exp. Ther., 285, 285 (1998); Ryberg, et al.: Br. J. Pharmacol., 152, 1092 (2007);Fórmula:C24H40O3Cor e Forma:Single SolutionPeso molecular:376.57CB2R PAM
CAS:CB2R PAM, an oral drug, boosts CB2 receptor response to specific agonists, showing potential in neuropathic pain relief.Fórmula:C21H24BrFN2O2Pureza:99.09%Cor e Forma:Green SolidPeso molecular:435.33AZD1940
CAS:AZD1940 (UNII-0J0035E9FT) is a high affinity CB(1)/CB(2) receptor agonist of the cannabinoid with oral activity. Application in the study of orofacial pain.Fórmula:C20H29F2N3O2SPureza:98.68%Cor e Forma:White SolidPeso molecular:413.525SCH-336
CAS:SCH-336: potent, selective CB2 agonist (Ki=1.8 nM, EC50=2 nM), orally active, 100x CB2 vs. CB1 preference, reduces leukocyte migration and eosinophilia.Fórmula:C23H25NO8S3Pureza:97.00%Cor e Forma:SolidPeso molecular:539.642CB1 agonist 1
CAS:CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.Fórmula:C24H24N2O5SPureza:98.89%Cor e Forma:Yellow SolidPeso molecular:452.523JTE-907
CAS:JTE-907 是一种具有高度选择性和口服活性的 CB2 受体反向激动剂。JTE-907在体内展现出抗炎活性。Fórmula:C24H26N2O6Pureza:99.93%Cor e Forma:SolidPeso molecular:438.47PSB-CB5
CAS:PSB-CB5 (GPR18-IN-32)2 is a GRP18 antagonist with anti-inflammatory activity and can be used to study obesity and metabolic disorders.Fórmula:C20H17ClN2O2SPureza:99.26%Cor e Forma:SolidPeso molecular:384.88Nonabine
CAS:Nonabine is a compound with strong antiemetic properties that can be used to prevent nausea and vomiting associated with cancer chemotherapy.Fórmula:C25H33NO2Pureza:99.82% - 99.94%Cor e Forma:White SolidPeso molecular:379.535SR144528
CAS:SR144528 is an antagonist of the CB2 receptor (Ki = 0.6 nM) and inhibits microsomal ACAT activity (IC50 = 3.6 μM).Fórmula:C29H34ClN3OPureza:99.63%Cor e Forma:SolidPeso molecular:476.05AM-1235
CAS:AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.Fórmula:C24H21FN2O3Pureza:99.92%Cor e Forma:Yellow SolidPeso molecular:404.4335Olorinab
CAS:Olorinab (APD 371) (APD 371) is a highly potent, selective and fully efficacious cannabinoid receptor type 2 (CB2) agonist. With an EC50 of 6.2 nM for hCB2.Fórmula:C18H23N5O3Pureza:97.67% - 98.47%Cor e Forma:White SolidPeso molecular:357.4069CB1R antagonist 1
CAS:CB1R antagonist 1 is a potent CB1R antagonist that can be used to study diseases related to the nervous system.Fórmula:C18H23F3N2O3SPureza:99.93%Cor e Forma:SolidPeso molecular:404.45Isopropyl dodec-11-enylfluorophosphonate
CAS:Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester functioning as a central cannabinoid receptor (CB1) antagonist and exhibitsFórmula:C15H30FO2PPureza:98%Cor e Forma:SolidPeso molecular:292.37AM841
CAS:AM841, a high-affinity electrophilic ligand, covalently interacts with a cysteine residue in helix six, thus activating the CB1 cannabinoid receptor.Fórmula:C26H39NO3SPureza:98%Cor e Forma:SolidPeso molecular:445.66OMDM-5
CAS:OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).Fórmula:C26H44N2O3Pureza:99.73%Cor e Forma:White SolidPeso molecular:432.6392MCHB-1
CAS:MCHB-1, a potent agonist of the human cannabinoid 2 (CB2) receptor (EC50= 0.52 nM), demonstrates high selectivity for CB2 over CB1 (Kis = 3.7 and 110 nM, respectively), distinguishing itself from similar benzimidazole compounds that significantly alleviate peripheral pain while minimizing central nervous system side effects in mice.Fórmula:C28H37N3O2Cor e Forma:SolidPeso molecular:447.623O-2545 hydrochloride
CAS:O-2545 is a potent water-soluble central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist with Ki values of 1.5 and 0.32 nM, respectively. Typically, cannabinoid agonists are highly lipophilic and require solubilization through surfactant agents or binding to water miscible substances like albumin, Tween 80, or Emulphor for use. When dissolved in saline, O-2545 has shown high efficacy in mouse behavioral models, administered either intravenously or intracerebroventricularly.Fórmula:C26H36N2O2HClCor e Forma:SolidPeso molecular:445Tricosanoyl Ethanolamide
CAS:Tricosanoyl ethanolamide, a fatty N-acyl ethanolamine within the endocannabinoid family, has an ethanolamine metabolite whose significance remains to be established.Fórmula:C25H51NO2Cor e Forma:SolidPeso molecular:397.688SAD-448
CAS:SAD-448 is a cannabinoid receptor type 1 (CB1) agonist. SAD-448 controls spasticity via action on the peripheral nerve CB1 receptor.Fórmula:C24H28N4O8SCor e Forma:SolidPeso molecular:532.57
