Ligações cruzadas de DNA
Foram encontrados 617 produtos de "Ligações cruzadas de DNA"
Eptaplatin
CAS:Platinum-based anti-tumor drugFórmula:C11H20N2O6PtPureza:Min. 95%Cor e Forma:PowderPeso molecular:471.37 g/molPNU 159682
CAS:DNA alkylating agent; highly potent metabolite of nemorubicinFórmula:C32H35NO13Pureza:Min. 90 Area-%Cor e Forma:Red PowderPeso molecular:641.62 g/molIdarubicin hydrochloride
CAS:Topoisomerase II inhibitor; daunorubicin analog; anti-leukemic; anthracycline
Fórmula:C26H28ClNO9Pureza:Min. 95%Cor e Forma:PowderPeso molecular:533.95 g/molSatraplatin
CAS:Platinum-based chemotherapeutic agentFórmula:C10H22Cl2N2O4PtPureza:Min. 95%Cor e Forma:Slightly Yellow PowderPeso molecular:500.28 g/molMitoxantrone hydrochloride
CAS:Inhibits DNA topoisomerase II; antineoplastic; immunomodulatory; antimicrobialFórmula:C22H30Cl2N4O6Pureza:Min. 97 Area-%Cor e Forma:Dark Blue SolidPeso molecular:517.4 g/molCarboplatin - Bio-X ™
CAS:Carboplatin is an antineoplastic alkylating agent that is used in the treatment of ovarian cancer. This drug attaches alkyl groups to nucleotides leading to the formation of monoadducts. Carboplatin’s main mechanism of action is preventing DNA strands from separating for synthesis and transcription.Fórmula:C6H12N2O4PtPureza:Min. 95%Cor e Forma:PowderPeso molecular:371.25 g/mol2-[2-[2-[2-[6-(Biotinylaminohexanoyl]aminoethoxy]ethoxy]ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester
CAS:Produto ControladoStability Light and Moisture Sensitive
Applications A cross-linking, biotin-labelled compound.
References Hatanaka, Y. et al: Bioorg. Med. Chem., 2, 1367 (1994); Hatanaka, Y. et al: J. Org. Chem., 59, 383 (1994); Hatanaka, Y. et al: Bioorg. Med. Chem. 2, 1367 (1994)Fórmula:C35H46F3N7O10SCor e Forma:NeatPeso molecular:813.843,4-Bis-(methanethiosulfonylmethyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxy Radical
CAS:Produto ControladoApplications A highly reactive thiol-specific cross-linking spin-label.
Fórmula:C12H22NO5S4Cor e Forma:NeatPeso molecular:388.57Temozolomide
CAS:Temozolomide is a cancer drug that belongs to the class of alkylating agents. It has been shown to have anticancer activity against human tumor cells in vitro. Temozolomide induces cell death by activating the apoptotic pathway. This drug also inhibits the cell cycle and blocks the G2-M phase, resulting in accumulation of cells at this point in the cell cycle. Temozolomide has been studied for its effects for cancer treatment in certain research approaches.Fórmula:C6H6N6O2Pureza:Min. 98 Area-%Cor e Forma:Off-White PowderPeso molecular:194.15 g/molPolyethylene Glycol Bis(3-aminopropyl) Ether
CAS:Cor e Forma:White to Light yellow to Dark green powder to lumpPalifosfamide
CAS:Active metabolite of ifosfamide; alkylates and cross-links DNA; antineoplasticFórmula:C4H11Cl2N2O2PPureza:Min. 95%Cor e Forma:SolidPeso molecular:221.02 g/molMal-PEG3-Acid
CAS:Fórmula:C13H19NO7Pureza:>95.0%(T)(HPLC)Cor e Forma:Colorless to Almost colorless clear liquidPeso molecular:301.30N-Succinimidyl Maleimidoacetate
CAS:Fórmula:C10H8N2O6Pureza:>95.0%(qNMR)Cor e Forma:White to Almost white powder to crystalPeso molecular:252.183-Sulfo-N-succinimidyl 4-(N-Maleimidomethyl)cyclohexane-1-carboxylate Sodium Salt
CAS:Fórmula:C16H17N2NaO9SPureza:>97.0%(qNMR)Cor e Forma:White to Almost white powder to crystalPeso molecular:436.37N-Succinimidyl 4-Maleimidobutyrate [Cross-linking Reagent]
CAS:Fórmula:C12H12N2O6Pureza:>98.0%(HPLC)(N)Cor e Forma:White to Light yellow to Light red powder to crystalPeso molecular:280.242-(Trihexylammonium)ethyl Methanethiosulfonate Bromide
Produto ControladoApplications A water soluble, bulkier analogue of the charged MTS reagent MTSET. Charged MTS reagents have been used successfully with SCAM (substituted cysteine accessibility method) to probe the topology and function of a number of ligand-gated ion channels and transporter proteins.
Fórmula:C21H46BrNO2S2Cor e Forma:NeatPeso molecular:488.632-[2-[2-(2-t-Boc-aminoethoxy]ethoxy]ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid Methyl Ester
CAS:Produto ControladoStability Light and Moisture Sensitive
Applications A cross-linking reagent.
References Hatanaka, Y. et al: Bioorg. Med. Chem., 2, 1367 (1994); Hatanaka, Y. et al: J. Org. Chem., 59, 383 (1994); Hatanaka, Y. et al: Bioorg. Med. Chem. 2, 1367 (1994)Fórmula:C21H28F3N3O7Cor e Forma:NeatPeso molecular:491.4581[5-(Trimethylammonium)pentyl] Methanethiosulfonate Bromide
Produto ControladoStability Moisture Sensitive
Applications Reacts specifically and rapidly with thiols to form mixed disulfides. Used to probe the structures of the ACh receptor channel of the GABAA receptor channel and of lactose permease.
References Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996), Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Vedantham, V. and Cannon, C.C.: J. Gen. Physiol., 111, 83 (1998), Lin, C.-W. and Tsung-Yu, C.: J. Gen. Physiol., 116, 535 (2000), Sullivan, D.A. and Cohen, J.B.: J. B.C., 275, 17, 12651 (2000)Fórmula:C9H22BrNO2S2Cor e Forma:NeatPeso molecular:320.313-(Triethylammonium)propyl Methanthiosulfonate Bromide
CAS:Produto ControladoStability Hygroscopic; Store at -20°C and Desiccate
Applications A water soluble, analogue of the charged MTS reagent MTSET. Charged MTS reagents have been used successfully with SCAM (substituted cysteine accessibility method) to probe the topology and function of a number of ligand-gated ion channels and transporter proteins.
References Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996), Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Vedantham, V. and Cannon, C.C.: J. Gen. Physiol., 111, 83 (1998)Fórmula:C10H24NO2S2·BrCor e Forma:NeatPeso molecular:334.34Tetraethoxy-d20-silane
CAS:Produto ControladoApplications Tetraethoxy-d20-silane (CAS# 272778-10-6) is a useful isotopically labeled research compound.
Fórmula:C8D20O4SiCor e Forma:NeatPeso molecular:228.45
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