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Ligações cruzadas de DNA

Ligações cruzadas de DNA

Os entrecruzadores de DNA são agentes químicos que criam ligações covalentes entre duas fitas de DNA, estabilizando a dupla hélice e inibindo a replicação e transcrição do DNA. Esses compostos são amplamente utilizados em pesquisas sobre câncer e no estudo dos mecanismos de reparo do DNA. Na CymitQuimica, oferecemos uma seleção de entrecruzadores de DNA para apoiar pesquisas em biologia molecular e genética.

Foram encontrados 617 produtos de "Ligações cruzadas de DNA"

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  • Mitoxantrone hydrochloride

    CAS:
    Inhibits DNA topoisomerase II; antineoplastic; immunomodulatory; antimicrobial
    Fórmula:C22H30Cl2N4O6
    Pureza:Min. 97 Area-%
    Cor e Forma:Dark Blue Solid
    Peso molecular:517.4 g/mol

    Ref: 3D-FM61451

    1g
    378,00€
    2g
    538,00€
    5g
    1.051,00€
    10g
    1.802,00€
    1kg
    14.037,00€
  • Idarubicin hydrochloride

    CAS:

    Topoisomerase II inhibitor; daunorubicin analog; anti-leukemic; anthracycline

    Fórmula:C26H28ClNO9
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:533.95 g/mol

    Ref: 3D-FI24535

    10mg
    282,00€
    25mg
    500,00€
    50mg
    780,00€
    100mg
    1.322,00€
    250mg
    2.575,00€
  • PNU 159682

    CAS:
    DNA alkylating agent; highly potent metabolite of nemorubicin
    Fórmula:C32H35NO13
    Pureza:Min. 90 Area-%
    Cor e Forma:Red Powder
    Peso molecular:641.62 g/mol

    Ref: 3D-FP158112

    5mg
    292,00€
    10mg
    412,00€
    25mg
    651,00€
    50mg
    1.002,00€
    100mg
    1.163,00€
  • Eptaplatin

    CAS:
    Platinum-based anti-tumor drug
    Fórmula:C11H20N2O6Pt
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:471.37 g/mol

    Ref: 3D-FE22772

    25mg
    354,00€
    50mg
    454,00€
    100mg
    673,00€
    250mg
    1.200,00€
  • Ifosfamide - Bio-X ™

    CAS:
    Ifosfamide is an alkylating agent and immunosuppressive drug used in chemotherapy for the treatment of various cancers such as ovarian, testicular, cervical and bladder. This drug interferes with the normal process of DNA replication causing damage to the DNA in cancer cells hence preventing them from growing and dividing.
    Fórmula:C7H15Cl2N2O2P
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:261.09 g/mol

    Ref: 3D-BI166243

    100mg
    135,00€
  • Satraplatin

    CAS:
    Platinum-based chemotherapeutic agent
    Fórmula:C10H22Cl2N2O4Pt
    Pureza:Min. 95%
    Cor e Forma:Slightly Yellow Powder
    Peso molecular:500.28 g/mol

    Ref: 3D-FS65158

    10mg
    184,00€
    50mg
    539,00€
  • 3,4-Bis-(methanethiosulfonylmethyl)-2,2,5,5-tetramethyl-2,5-dihydro-1H-pyrrol-1-yloxy Radical

    Produto Controlado
    CAS:

    Applications A highly reactive thiol-specific cross-linking spin-label.

    Fórmula:C12H22NO5S4
    Cor e Forma:Neat
    Peso molecular:388.57

    Ref: TR-B485940

    1mg
    347,00€
    10mg
    2.315,00€
  • 2-[2-[2-[2-[6-(Biotinylaminohexanoyl]aminoethoxy]ethoxy]ethoxy]-4-[3-(trifluoromethyl)-3H-diazirin-3-yl]benzoic Acid N-Hydroxysuccinimide Ester

    Produto Controlado
    CAS:

    Stability Light and Moisture Sensitive
    Applications A cross-linking, biotin-labelled compound.
    References Hatanaka, Y. et al: Bioorg. Med. Chem., 2, 1367 (1994); Hatanaka, Y. et al: J. Org. Chem., 59, 383 (1994); Hatanaka, Y. et al: Bioorg. Med. Chem. 2, 1367 (1994)

    Fórmula:C35H46F3N7O10S
    Cor e Forma:Neat
    Peso molecular:813.84

    Ref: TR-B394866

    500µg
    369,00€
    5mg
    2.735,00€
  • Mal-PEG3-Acid

    CAS:
    Fórmula:C13H19NO7
    Pureza:>95.0%(T)(HPLC)
    Cor e Forma:Colorless to Almost colorless clear liquid
    Peso molecular:301.30

    Ref: 3B-D6570

    250mg
    134,00€
  • N-Succinimidyl 4-Maleimidobutyrate [Cross-linking Reagent]

    CAS:
    Fórmula:C12H12N2O6
    Pureza:>98.0%(HPLC)(N)
    Cor e Forma:White to Light yellow to Light red powder to crystal
    Peso molecular:280.24

    Ref: 3B-S0399

    100mg
    36,00€
    1g
    181,00€
    5g
    559,00€
  • 3-Sulfo-N-succinimidyl 4-(N-Maleimidomethyl)cyclohexane-1-carboxylate Sodium Salt

    CAS:
    Fórmula:C16H17N2NaO9S
    Pureza:>97.0%(qNMR)
    Cor e Forma:White to Almost white powder to crystal
    Peso molecular:436.37

    Ref: 3B-S0883

    20mg
    64,00€
    100mg
    190,00€
  • N-Succinimidyl Maleimidoacetate

    CAS:
    Fórmula:C10H8N2O6
    Pureza:>95.0%(qNMR)
    Cor e Forma:White to Almost white powder to crystal
    Peso molecular:252.18

    Ref: 3B-S0968

    100mg
    205,00€
  • Temozolomide

    CAS:
    Temozolomide is a cancer drug that belongs to the class of alkylating agents. It has been shown to have anticancer activity against human tumor cells in vitro. Temozolomide induces cell death by activating the apoptotic pathway. This drug also inhibits the cell cycle and blocks the G2-M phase, resulting in accumulation of cells at this point in the cell cycle. Temozolomide has been studied for its effects for cancer treatment in certain research approaches.
    Fórmula:C6H6N6O2
    Pureza:Min. 98 Area-%
    Cor e Forma:Off-White Powder
    Peso molecular:194.15 g/mol

    Ref: 3D-FT28027

    10g
    435,00€
    25g
    736,00€
    50g
    1.038,00€
    100g
    1.757,00€
    250g
    2.528,00€
  • Polyethylene Glycol Bis(3-aminopropyl) Ether

    CAS:
    Cor e Forma:White to Light yellow to Dark green powder to lump

    Ref: 3B-P1948

    1g
    38,00€
    5g
    116,00€
  • Palifosfamide

    CAS:
    Active metabolite of ifosfamide; alkylates and cross-links DNA; antineoplastic
    Fórmula:C4H11Cl2N2O2P
    Pureza:Min. 95%
    Cor e Forma:Solid
    Peso molecular:221.02 g/mol

    Ref: 3D-FP65121

    2mg
    210,00€
  • N-Boc-Ethylenediamine-D4

    Produto Controlado
    CAS:

    Applications A is the deuterated isotope of N-Boc-Ethylenediamine (B655006). N-Boc-Ethylenediamine is used in the synthesis of Thyronamine derivatives and analogs.
    References Anon., et al.: J. Pharmacol., 58, 53 (1936), Boissier, J., et al.: Eur. J. Pharmacol., 22, 141 (1973),

    Fórmula:C7H12D4N2O2
    Cor e Forma:Neat
    Peso molecular:164.24

    Ref: TR-B655006

    5mg
    127,00€
    10mg
    195,00€
  • 3-(Triethylammonium)propyl Methanthiosulfonate Bromide

    Produto Controlado
    CAS:

    Stability Hygroscopic; Store at -20°C and Desiccate
    Applications A water soluble, analogue of the charged MTS reagent MTSET. Charged MTS reagents have been used successfully with SCAM (substituted cysteine accessibility method) to probe the topology and function of a number of ligand-gated ion channels and transporter proteins.
    References Duhten, R.L., et al.: Biochemistry, 32, 3139 (1993), Yang, N. et al.: Neuron, 16, 113 (1996), Kuner, T. et al.: Neuron, 17, 343 (1996), Holmgren, M. et al: Neuropharmacology, 35, 797 (1996), Chahine, M. et al.: Biochemical & Biophysical Res. Commun., 233, 606 (1997), Ehrlich, B.E., et al.: J. Gen. Physiol., 109, 255 (1997), Rassendren, F., et al.: The EMBO Journal, 16, 3446 (1997), Vedantham, V. and Cannon, C.C.: J. Gen. Physiol., 111, 83 (1998)

    Fórmula:C10H24NO2S2·Br
    Cor e Forma:Neat
    Peso molecular:334.34

    Ref: TR-T776300

    10mg
    254,00€
    25mg
    545,00€
  • Silicon 2,3-Naphthalocyanine Bis(trihexylsilyloxide)

    CAS:
    Fórmula:C84H102N8O2Si3
    Cor e Forma:Neat
    Peso molecular:1340.018

    Ref: TR-S456535

    250mg
    1.621,00€
  • 2-(Trihexylammonium)ethyl Methanethiosulfonate Bromide

    Produto Controlado

    Applications A water soluble, bulkier analogue of the charged MTS reagent MTSET. Charged MTS reagents have been used successfully with SCAM (substituted cysteine accessibility method) to probe the topology and function of a number of ligand-gated ion channels and transporter proteins.

    Fórmula:C21H46BrNO2S2
    Cor e Forma:Neat
    Peso molecular:488.63

    Ref: TR-T794550

    10mg
    236,00€
    100mg
    1.574,00€
  • 2-(Tripentylammonium)ethyl Methanethiosulfonate Bromide, Technical Grade, >65%

    Produto Controlado
    CAS:

    Stability Temperature and Moisture Sensitive
    Applications A water soluble, bulkier analogue of the charged MTS reagent MTSET. Charged MTS reagents have been used successfully with SCAM (substituted cysteine accessibility method) to probe the topology and function of a number of ligand-gated ion channels and transporter proteins.

    Fórmula:C18H40NO2S2·Br
    Pureza:>65%
    Cor e Forma:Neat
    Peso molecular:446.55

    Ref: TR-T808450

    10mg
    106,00€
    100mg
    769,00€