Açúcares e Nucleobases da Espinha Dorsal
Foram encontrados 1001 produtos de "Açúcares e Nucleobases da Espinha Dorsal"
3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine
CAS:Please enquire for more information about 3’,5’-Di-O-acetyl-2’-azido-2’-deoxy-5-methyluridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePureza:Min. 95%1,3-Dimethyluracil
CAS:1,3-Dimethyluracil is a uracil derivative that is used as a hydrogen-bond donor, which helps to repair DNA. It has been shown to have a kinetic isotope effect in the deuterium isotope effect studies. The carbonyl group of 1,3-dimethyluracil can form hydrogen bonds with the guanine base in DNA and lead to the formation of an adduct. This adduct can be repaired by nucleotide excision repair when it forms a dimer with another 1,3-dimethyluracol molecule or by base excision repair when it forms a dimer with another purine or pyrimidine base. Aqueous solutions of 1,3-dimethyluracil are stable for short periods of time but decompose rapidly on heating. X-ray crystal structures show that 1,3-dimethyluracil binds to hydrochloric acid and x-ray crystallographic analysisFórmula:C6H8N2O2Pureza:Min. 95%Cor e Forma:Off-White Slightly Brown PowderPeso molecular:140.14 g/molHypoxanthine monosodium salt
CAS:Hypoxanthine is a nucleotide, which is a building block of DNA and RNA. It is a useful intermediate for the production of other chemicals and drugs. Hypoxanthine can be used as a reagent in biochemical research, to study the effects of hypoxia on cells, or as a catalyst in organic synthesis. Hypoxanthine monosodium salt is an important building block for complex compounds with many uses. It is also used as a reaction component in many chemical reactions as well as being a versatile scaffold for drug design.Fórmula:C5H4N4NaOPureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:159.1 g/molNb-N-(benzhydryloxycarbonyl)cytosine)-1-acetic acid
CAS:Nb-N-(benzhydryloxycarbonyl)cytosine)-1-acetic acid is a speciality chemical that is used as a reagent, building block, and scaffold for organic synthesis. This compound can be used in various reactions to produce complex compounds with high purity. Nb-N-(benzhydryloxycarbonyl)cytosine)-1-acetic acid is an excellent starting material for the production of fine chemicals, research chemicals, and versatile building blocks. It is also a useful intermediate for the production of pharmaceuticals and other useful compounds.Fórmula:C20H17N3O5Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:379.37 g/mol6-Amino-1,3-dimethyluracil
CAS:6-Amino-1,3-dimethyluracil is a synthetic compound that has been shown to have antiinflammatory activity. This drug was synthesized from recycled methylene biphenyls and quinoline derivatives. 6-Amino-1,3-dimethyluracil inhibits the synthesis of proteins in cells by inhibiting the production of amino acids such as methionine through an attack on the amino group of methionine. 6-Amino-1,3-dimethyluracil also has apoptotic activity, which may be due to its ability to inhibit protein synthesis and increase the levels of active methylene.Fórmula:C6H9N3O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:155.15 g/mol3'-Deoxy-2',3'-Didehydro-2'Fluorothymidine
CAS:3'-Deoxy-2',3'-Didehydro-2'Fluorothymidine (3DFT) is a nucleoside analogue of thymidine. It has been shown to be an efficient inhibitor of HIV replication in vitro and in vivo. 3DFT is able to inhibit virus production by blocking the viral reverse transcriptase enzyme, which is responsible for copying the viral genomic RNA into DNA. This drug also inhibits the activity of human immunodeficiency virus type 1 integrase, which is an enzyme that catalyses the integration of proviral DNA into host cell chromosomes. 3DFT is a potent inhibitor of HIV infection in vitro and in vivo and has also been shown to inhibit other viruses such as cytomegalovirus, herpes simplex virus types 1 and 2, varicella zoster virus, influenza A virus, coxsackie B4 virus, echovirus 7, and erythrovirus 9.Fórmula:C10H11FN2O4Pureza:Min. 95%Peso molecular:242.2 g/mol3’-Deoxy-5-fluorouridine
CAS:3’-Deoxy-5-fluorouridine is a synthetic compound that is used as an anticancer drug. It has been shown to induce apoptosis in cancer cells through the modulation of polymerase, synthetase and other enzymes involved in DNA synthesis. 3’-Deoxy-5-fluorouridine also inhibits the activity of viral thymidylate synthase, which prevents the conversion of deoxyuridine triphosphate (dUTP) to thymidylate monophosphate (dTMP), preventing DNA replication and cell division. This chemical can be synthesized by reacting uracil with trifluoroacetic acid followed by saponification.
Pureza:Min. 95%9-Deazaguanine
CAS:9-Deazaguanine is an analog of guanine, which has inhibitory properties. It reacts with the hydrogen bond of the enzyme and prevents its reaction with a substrate. 9-Deazaguanine binds to the target enzymes trifluoroacetic acid (TFA) and hydrogen bond interactions with water molecules. The reaction mechanism is based on the competitive inhibition of TFA, which is an important enzyme in DNA synthesis. 9-Deazaguanine inhibits the growth of k562 cells by inhibiting protein synthesis at specific sites in the ribosome. 9-Deazaguanine also shows inhibitory properties against autoimmune diseases and infectious diseases because it inhibits immune system reactions that are mediated by antibodies and T cells.
Fórmula:C6H6N4OPureza:Min. 95%Cor e Forma:PowderPeso molecular:150.14 g/mol3’,5’-Bis-O-benzoyl-2’-deoxy-2’-fluoro-β-D-arabino-6-azidouridine
CAS:Please enquire for more information about 3’,5’-Bis-O-benzoyl-2’-deoxy-2’-fluoro-beta-D-arabino-6-azidouridine including the price, delivery time and more detailed product information at the technical inquiry form on this pagePureza:Min. 95%9-Methylxanthine
CAS:Produto Controlado9-Methylxanthine is a purine alkaloid that is structurally related to caffeine. It is used as a bronchodilator and to treat cardiac arrhythmias. 9-Methylxanthine has been shown to have an effect on the rate of DNA replication by binding to the enzyme xanthosine phosphorylase, which converts xanthosine monophosphate (XMP) to xanthosine diphosphate (XDP). The drug's effect on other nucleobases, such as adenosine monophosphate (AMP), cannot be ruled out. 9-Methylxanthine also has a strong affinity for macrochelates, which are compounds that contain chelating agents with a large number of ethylenediaminetetraacetic acid (EDTA) groups. This property is due to the high number of nitrogen atoms in the molecule and its ability to form hydrogen bonds between water moleculesFórmula:C6H6N4O2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:166.14 g/mol6-Mercaptopurine
CAS:6-Mercaptopurine is an antigen binding molecule that is biocompatible with the human body. It binds to 6-mercaptopurine and inhibits the oxidation of proteins. The inhibition of protein oxidation has been shown to decrease disease activity in patients with inflammatory bowel disease. 6-Mercaptopurine also inhibits the production of inhibitor molecules, which are responsible for the development of cardiac effects such as arrhythmias and cardiomyopathy. 6-Mercaptopurine has inhibitory properties against polymerase chain reactions, which may be due to its ability to bind with protein thiols at high rates.Fórmula:C5H4N4SPureza:Min. 98 Area-%Cor e Forma:PowderPeso molecular:152.18 g/mol3’-Deoxy-3’-fluoro-6-thioinosine
CAS:Please enquire for more information about 3’-Deoxy-3’-fluoro-6-thioinosine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Pureza:Min. 95%3-Benzyladenine
CAS:Produto ControladoApplications 3-BENZYLADENINE (cas# 7280-81-1) is a useful research chemical.
Fórmula:C12H11N5Cor e Forma:NeatPeso molecular:225.259N-Trityl Guanine
CAS:Produto ControladoApplications Protected Guanine.
References Hakimelahi, G., et al.: J. Med. Chem., 44, 3710 (2001),Fórmula:C24H19N5OCor e Forma:NeatPeso molecular:393.44Uracil Lyxonucleoside-13C,15N2 5'-Phosphate
CAS:Produto ControladoApplications Uracil Lyxonucleoside 5'-Phosphate is an intermediate in the synthesis of Trilithium UDP-glucuronic Acid-13C1, 15N2 (T886287), which is an isotope labelled analog of Trisodium UDP-glucuronic Acid (T886285). Trisodium UDP-glucuronic Acid is a reactant used in the enzymatic preparation of β-glucuronides.
References Stevenson, D.E., et. al.: Collect Czech. Chem. C., 65, 117 (2000); Robotham, S.A., Brodbelt, J.S.: Biochem. Pharmacol., 82, 1764 (2011); Kren, V., et. al.: Drug Metab. Dispos., 28, 1513 (2000)Fórmula:C813CH1315N2O9PCor e Forma:NeatPeso molecular:327.16N2,9-Diacetylguanine
CAS:Produto ControladoImpurity Acicclovir EP Impurity L
Applications N2,9-Diacetylguanine (Acicclovir EP Impurity L) is used to synthesize acyclic analogues of deoxyguanosine.
References Martin, J. C., et al.: J Med Chem. 26, 759 (1983)Fórmula:C9H9N5O3Cor e Forma:NeatPeso molecular:235.2N-Allyl-1,7-dideazaadenine
CAS:Produto ControladoApplications Used in the preparation of pyrrolotriazines.
Fórmula:C10H11N3Cor e Forma:NeatPeso molecular:173.21Diisopropylammonium Tetrazol-1-ide
CAS:Fórmula:C6H15N·CH2N4Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:171.258-Chloroadenine
CAS:8-Chloroadenine is an antimicrobial agent that inhibits the DNA replication of bacteria by binding to the dna template. It is a potent inhibitor of oxidative DNA damage and has been shown to be effective against various bacteria, including Staphylococcus aureus. 8-Chloroadenine also has reactive properties and can react with chloride in the environment to form hypochlorous acid (HOCl) and 8-chloroguanine. This compound may also act as an enzyme catalyst for the enzymatic reaction between hypochlorous acid and chloride ions.Fórmula:C5H4ClN5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:169.57 g/mol7-Deaza-6-hydroxypurine
CAS:7-Deaza-6-hydroxypurine is a skeleton of nucleosides that inhibits enzymes. It has been shown to inhibit the activity of hydrochloric acid, a tumor metastasis promoter. The constant for this drug was determined using molecular modeling and inhibition constants. 7-Deaza-6-hydroxypurine has anticancer activity and can be used for the treatment of cancer. This drug is used as a noncompetitive inhibitor in which it binds to two different sites on the enzyme. It has also been shown to bind to subunits, which are parts of a protein that make up its structure, in biological studies.br> 7-Deaza-6-hydroxypurine is an inhibitor that binds to two different sites on an enzyme. It has been shown to have anticancer activity and can be used for the treatment of cancer. This drug is used as a noncompetitive inhibitor in which it binds to two different sites on the enzyme. ItFórmula:C6H5N3OPureza:Min. 95%Cor e Forma:PowderPeso molecular:135.12 g/mol
