Lípidos

Applications 3-Oxo-7a-hydroxy-5β-cholanoic Acid is a keto bile acid derivative.
References Bortolini, O. et al.: Tetra., 62, 4482 (2006); Bortolini, O. et al.: J. Org. Chem., 67, 5802 (2002);

Applications Glyceryl Trinonadecanoate is used in the study of Polymorphism and transformation energetics of saturated monoacid triglycerides.
References Hagemann, J., et al.: JAOCS, 60, 1123 (1983)

Stability Hygroscopic
Applications (R)-Butyryl Carnitine is a potential prodrug of Carnitine, used for treating seizure disorders.
References Fei, Y., et al.: J. Biol. Chem., 275, 23707 (2000), Duran, J., et al.: J. Membr. Biol., 185, 65 (2002), Brown, A., et al.: J. Biol. Chem., 278, 11312 (2003), Gupta, N., et al.: Life Sci., 78, 2419 (2006),

Applications A phytosterol content in plant food which showed hypocholesterolemic and hypotriglyceridemic effects in hypercholesterolemic overweight volunteers. Used in the treatment of metabolic disorders.
References Kasamo, K., et al.: Plant Physiol., 93, 1049 (1990), Davey, M., et al.: J. Sci. Food Agric., 80, 825 (2000), Nomura, T., et al.: J. Biol. Chem., 280, 17873 (2005), Matos, L., et al.: Food Chem., 102, 406 (2007),

Applications A metabolite of Ursodeoxycholic Acid, which is used as an anticholelithogenic.

Applications The major sphinganine from the ceramides phospholipids of Bacteroides melaninogenicus as arachidonate cascade inhibitor and blood platelet aggregation inhibitor.
References Dennis, R., et al.: Eur. J. Biochem., 146, 51 (1985), Dennis, R., et al.: J. Biol. Chem., 260,, 5370 (1985), Field, K., et al.: Science, 239, 748 (1988),

Applications n-Dodecyl β-D-Maltoside is a widely used detergent to solubilize membrane proteins.
References Hildebrandt, E., et. al.: BBA-Biomembranes, 1838, 2825 (2014)

Applications Fatty acid ester with glycerol from banana fruit residues as source of valuable phytosterols.
References Banskota, A., ET AL.: Biol. Pharm. Bull., 23, 456 (2000), Luo, H., ET AL.: J. Nat. Prod., 68, 94 (2005), Oliveira, L., et al.: J. Agric. Food Chem., 54, 2598 (2006), Oliveira, L., et al.: Ind. Crops Prod., 26, 163 (2007),

Applications A metabolite of Cholesterol. Its membrane organizing properties could have implications in Altzheimer’s disease.
References Wang, J., et al.: Biochemistry, 43, 1010 (2004), Lemaire-Ewing, S., et al.: Cell Biol. Toxicol., 21, 97 (2005), Fuda, H., et al.: J. Lipid Res., 48, 1343 ( 2007), Sasaki, H., et al.: Metabolism, 56, 357 (2007); S.L. Regen et al.: J. Amer. Chem. Soc., 131, 12354 (2009)

Applications (S)-(-)-Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling. (S)-(-)-Canadine has a strong central nervous system-depressing activity and is used in the preparation of tetrahydroprotoberberine derivatives as new antipsychotic agents.
References Sun, H. et al.: Bioorg. Med. Chem., 21, 856 (2013); Deeb, O., et al.: Chem. Biol. Drug Des., 76, 255 (2010); Sun., et al.: Br. J. Pharmcol., 158, 1302 (2009); Duchowicz, P., et al.: Bioorg. Med. Chem., 14, 5876 (2006); Yamahara, J. et al.: Chem. Pharm. Bull., 24, 1909 (1976)

Applications 12-Hydroxylauric Acid is used in the structural and functional characterization of S-nitrosoglutathione reductase from Solanum lycopersicum.
References Kubienova, L., et. al.: Biochimie, 95, 889 (2013)

Applications β-Sitosteryl Ferulate is used for purification and identification of components of γ-oryzanol in rice bran oill
References Xu, Z., et al.: J. Agric. Food Chem., 47, 2724 (1999);

Applications A metabolite in human hepatic bile. A lithocholic acid analog that inhibit sialyltransferase.
References Ishikawa, H., et al.: J. Lipid. Res., 40, 1920 (1999), Gustafsson, U., et al.: Eur. J. Clin. Invest., 30, 1099 (2000), Gowda, G., et al.: Lipids, 41, 591 (2006), Lindon, J., et al.: Pharm. Res., 23, 1075 (2006),

Applications An oxygenated derivative of Cholesterol (C432501); an oxysterol. An inhibitor of human immunodeficiency virus replication in vitro. It induces apoptosis in human monocytic cell lines as well as inducing apoptosis in CEM cells associated with negative regulation of c-Myc.
References Aupeix, K. et al.: Immunobiology, 194, 415 (1995); Moog, C. et al.: Antivir. Chem, Chemother., 9, 491 (1998); Ayala-Torres, S. et al.: Exp. Cell Res., 246, 193 (1999);

Applications 5α-Cholesta-7,24-diene-3β-ol, is the derivative of Zymosterol (Z701520). It can also be used for identification of a new plasma biomarker of Alzheimer's disease using metabolomics technology.
References Sato, Y., et al.: J. Lipid Res., 53, 567 (2012); Schoenheimer, et al.: J. Biol. Chem., 105, 355 (1934);

Stability Hygroscopic
Applications 3-Oxo-7α,12α-hydroxy-5β-cholanoic Acid is a keto bile acid derivative.
References Bortolini, O. et al.: Tetra., 62, 4482 (2006); Bortolini, O. et al.: J. Org. Chem., 67, 5802 (2002); Iguchi, Y. et al.: Biol. Pharm. Bull., 34, 1 (2011);