Nucleotídeos
Os nucleotídeos são compostos orgânicos que servem como building blocks dos ácidos nucleicos, essenciais para a formação de DNA e RNA. Cada nucleotídeo é composto por uma base nitrogenada, uma molécula de açúcar e um ou mais grupos fosfato. Esses nucleotídeos se unem para formar longas cadeias, criando o material genético que carrega e transmite informações genéticas em todos os organismos vivos. Nesta seção, você encontrará uma ampla variedade de nucleotídeos cruciais para pesquisas em genética, biologia molecular e bioquímica. Eles são fundamentais para estudar processos genéticos, sintetizar ácidos nucleicos e desenvolver ferramentas diagnósticas e terapêuticas. Na CymitQuimica, oferecemos nucleotídeos de alta qualidade para apoiar suas pesquisas científicas e aplicações, garantindo precisão e confiabilidade em seus experimentos.
Subcategorias de "Nucleotídeos"
Foram encontrados 2638 produtos de "Nucleotídeos"
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5-Iodouridine
CAS:5-Iodouridine is a pyrimidine nucleoside that is found in the human body. It is used as a starting material for the synthesis of 5-iodo-2'-deoxyuridine, which has been shown to have biological properties. 5-Iodouridine binds to the dna template and prevents radiation from altering it's conformation. This binding has been shown to be specific for ultraviolet (UV) radiation, with little absorption at visible wavelengths. The biological effects of 5-iodouridine are dependent on its acidic pH and hydrogen bonding ability. In vitro assays have demonstrated that this compound can inhibit prostate cancer cells from proliferating and may be useful in treating cervical cancer.Fórmula:C9H11IN2O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:370.1 g/mol2'-C-Methylguanosine 5'-diphosphate triethylammonium salt
2'-C-Methylguanosine 5'-diphosphate triethylammonium salt is a synthetic nucleotide analog for use in researchFórmula:C11H16N5O11P2·C18H45N3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:759.79 g/molE-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine
CAS:E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is a nucleoside that is a modified form of uridine. It is a nucleotide analog that inhibits the synthesis of DNA and RNA and can be used to treat cancer. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine is an activator that activates the phosphoramidites in the synthesis of DNA and RNA. This drug can also be used as antiviral therapy for herpes simplex virus type 1, influenza virus, and HIV. E-5-(2-Carbomethoxyvinyl)-2'-deoxyuridine has been shown to have anti-inflammatory properties by inhibiting prostaglandin synthesis.Fórmula:C13H16N2O7Pureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:312.28 g/mol5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine
CAS:5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine is a modified nucleoside analog that inhibits the synthesis of DNA and RNA. It has been shown to have antiviral, anticancer, and antiinflammatory activities. 5-O-[[[(1S)-1-Methyl-2-(1-methylethoxy)-2-oxoethyl]amino]-phenoxyphosphinyl]-cytidine is a ribonucleoside that can be used as a building block for the production of deoxyribonucleosides (i.e., as an activator). This product also has high purity and quality, as well as being novel in structure.Fórmula:C21H29N4O9PPureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:512.45 g/molN2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine
N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2-aminopurine is a nucleoside that is modified with a chlorine group. The modification of the nucleoside may enhance its anticancer activity. N2-Diboc-7/9-(2,3,4,6-tetra-O-acetyl-D-mannopyranosyl)-6-chloro-2 aminopurine has been shown to inhibit the growth of virus and cancer cells by inhibiting DNA synthesis. It has also been shown to induce apoptosis in human leukemia cells.Fórmula:C21H30ClN5O9Pureza:Min. 95%Cor e Forma:White to beige solid.Peso molecular:531.94 g/molCytidine-2'-monophosphate sodium
CAS:Cytidine-2'-monophosphate sodium (CMP) is a nucleotide that is used as a monophosphate or diphosphate. It can be used to synthesize DNA and RNA. CMP also has antiviral, anticancer, and high purity properties. CMP is an activator of DNA polymerases and helps in the synthesis of DNA. It has novel properties that make it different from other nucleotides, such as its modified sugar moiety.Fórmula:C9H12Na2N3O8PPureza:Min. 90%Cor e Forma:PowderPeso molecular:367.18 g/mol5'-O-DMT-2'-O-methyl-N6-phenylacetyladenosine
5'-O-DMT-2'-O-methyl-N6-phenylacetyladenosine is a synthetic nucleoside with anticancer properties. It is modified to be more resistant to phosphodiesterase which blocks the synthesis of DNA and RNA. This drug has been shown to activate the immune system, inhibit tumor growth, and inhibit viral replication. It has been shown to be effective in animal models against leukemia and lymphoma. The high quality pure chemical will be used for use in research purposes only.Pureza:Min. 95%6-O-Methylinosine
CAS:6-O-Methylinosine is a modified nucleoside that is used in the synthesis of recombinant proteins. It is synthesized from the reaction of methylphosphate and 6-O-methylguanosine. The phosphate group of the 6-O-methylguanosine molecule reacts with methylphosphate in an acid or neutral environment, while it reacts with phosphoric acid in a basic environment. This reaction can be monitored by measuring the amount of free phosphate groups present after the reaction. The rate of this reaction can be increased by increasing temperature and pH. 6-O-Methylinosine has been shown to have anticancer activity, which may be due to its ability to inhibit enzyme catalysis and modify DNA structure.Fórmula:C11H14N4O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:282.25 g/mol7-Deaza-2'-deoxyguanosine
CAS:7-Deaza-2'-deoxyguanosine is an analog of guanosine that has been shown to inhibit the activity of telomerase. This enzyme synthesizes a sequence of DNA called a telomere, which protects the ends of chromosomes from deterioration and prevents chromosomal end-to-end fusion. 7-Deaza-2'-deoxyguanosine has an inhibitory effect on the polymerase chain reaction (PCR) in mammalian cells and inhibits the transcription-polymerase chain reaction (PCR) in vitro. It has also been shown to be potent against cancer cells. 7-Deaza-2'-deoxyguanosine is synthesized by solid phase synthesis, which is a chemical process that involves attaching one molecule to another molecule with similar structure, using organic solvents as intermediates.Fórmula:C11H14N4O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:266.26 g/mol2'-Deoxy-2'-fluoro-L-uridine
CAS:2'-Deoxy-2'-fluoro-L-uridine is a synthetic nucleoside analog of uridine where the sugar is both fluorinated at the 2' position and in the L-configuration, which is the mirror image of naturally occurring D-nucleosides. This modification makes it structurally distinct and biologically significant for certain applications in drug development and biochemical research.
Fórmula:C9H11FN2O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:246.2 g/mol2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine
CAS:2-Amino-6-chloro-9-(2'-deoxy-b-D-ribofuranosyl)purine is a purine nucleoside where the purine base has a 2-amino group at position 2 and a chlorine at position 6. The sugar is 2'-deoxy, meaning it is like the sugar found in DNA, lacking the 2'-hydroxyl group that is present in RNA. The amino and chloro groups on the purine base modify how this molecule behaves in biological systems making it useful in research applications.Fórmula:C10H12ClN5O3Pureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:285.69 g/mol5-Methyluridine
CAS:5-Methyluridine is a nucleoside that is used to inhibit the replication of cells. It is also used for the treatment of cancer, infectious diseases, and other conditions. 5-Methyluridine inhibits cellular replication by binding to ribothymidine and uridine in the nucleus. The inhibition of cellular proliferation is due to a lack of dna synthesis and RNA synthesis. This nucleoside has been shown to have inhibitory properties against mouse tumor cells grown in vitro, as well as the wild-type strain grown in vivo. 5-Methyluridine may be useful for the treatment of cancer tissues because it can suppress the growth of tumors by inhibiting their ability to replicate.Fórmula:C10H14N2O6Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:258.23 g/molTrifluorothymidine
CAS:Treats herpes-associated keratitis and keratoconjunctivitis; antineoplasticFórmula:C10H11F3N2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:296.2 g/molCytidine-5'-diphosphate trisodium
CAS:Cytidine-5'-diphosphate trisodium (CDP-Tris) is a copolymerization agent that contains a formamide molecule, which is used to increase the viscosity of the polymer. It is also used as a hydrogen bond donor and acceptor in the synthesis of polymers. CDP-Tris can be used for DNA replication and repairs damaged DNA by binding to 7-methylguanine, one of the most common lesions found in DNA. This agent has been shown to be effective in diluting crude cell extracts from E. coli bacteria. CDP-Tris is also used to synthesize polymers with 3-methylcytidine monomers that contain nitrogen atoms. These polymers are then used as substitutes for natural polymers such as cellulose and starch, which can be difficult to process because they are hydrophobic.Fórmula:C9H12N3Na3O11P2Pureza:Min. 95 Area-%Cor e Forma:White Yellow PowderPeso molecular:469.12 g/mol2',3'-Di-O-acetyl-D-uridine
CAS:2',3'-Di-O-acetyl-D-uridine is a nucleoside for use in research applicationsFórmula:C13H16N2O8Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:328.27 g/mol2'-Deoxy-6-methylthioguanosine
CAS:2'-Deoxy-6-methylthioguanosine is a novel nucleoside and nucleotide analog with antiviral and anticancer activities. It has been shown to inhibit the replication of DNA by inhibiting the activity of DNA polymerase. The target of this drug is not related to any virus or bacterial species, but it inhibits the growth of cancer cells in vitro. The synthesis of 2'-deoxy-6-methylthioguanosine can be achieved by modifying commercially available phosphoramidites.Fórmula:C11H15N5O3SPureza:Min. 95%Cor e Forma:PowderPeso molecular:297.33 g/mol2'-O-Benzoyl-5'-O-DMT-4-thiouridine
2'-O-Benzoyl-5'-O-DMT-4-thiouridine is a phosphoramidite monophosphate nucleoside analog. It has antiviral and anticancer properties, and has been shown to activate the immune system in mice. 2'-O-Benzoyl-5'-O-DMT-4-thiouridine is also novel because it is structurally different from all other nucleosides that have been studied for antiviral and anticancer activity. This drug can be used as an activator of DNA synthesis in vitro.Fórmula:C37H34N2O8SPureza:Min. 95%Cor e Forma:Yellow SolidPeso molecular:666.76 g/mol3',5'-O-(1,1,3,3-Tetraisopropyldisiloxane-1,3-diyl)-2'-ketouridine
CAS:Used as a protected 2'-ketouridine nucleoside in the synthesis of modified RNA oligonucleotides. The 1,1,3,3-tetraisopropyldisiloxane-1,3-diyl (TIPDS or TBDPSi2) group protects the 3' and 5' hydroxyl groups, while the 2'-keto (or 2'-oxo) modification introduces a specific functional group at the 2' position of the ribose sugar.Fórmula:C21H36N2O7Si2Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:484.69 g/mol2'-O-Methyladenosine
CAS:2'-O-Methyladenosine (2'-OMeA) is a nucleoside that is a low-energy analog of adenosine. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. 2'-OMeA has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). 2'-OMeA inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides. The chemical structures of 2'-OMeA are similar to those found in fatty acids and can be detected using chemical ionization mass spectroscopy. The sequence for 2'-OMeA was determined through sequencing methods including NMR spectroscopy and nuclear magnetic resonance data analysis.Fórmula:C11H15N5O4Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:281.27 g/mol5-Fluorouridine-5'-triphosphate triethylammonium salt - aqueous solution
5-Fluorouridine-5'-triphosphate triethylammonium salt - aqueous solution is an activated nucleoside that is synthesized from the triethylamine salt of 5-fluorouridine. This product has antiviral and anticancer activities, and can be used as a DNA-synthesizing agent in the synthesis of deoxyribonucleosides. It has been shown to inhibit replication of human immunodeficiency virus (HIV) by inhibiting viral reverse transcriptase, as well as cytomegalovirus (CMV) by inhibiting viral DNA polymerase.
Fórmula:C33H74N6O15P3FPureza:Min. 95%Cor e Forma:Colorless PowderPeso molecular:906.89 g/mol
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