Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt
CAS:2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt is a nucleoside that can be used as an antiviral or anticancer drug. It is a modified nucleoside, which is synthesized by phosphoramidite chemistry. 2'-O-Methyl-5'-methyluridine 5'-triphosphate triethylammonium salt has been shown to be an activator of DNA polymerase in vitro and in vivo. It also has high purity and high quality.Fórmula:C11H19N2O15P3Pureza:Min. 95%Peso molecular:512.19 g/mol5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-deoxyuridine 3'-CE phosphoramidite is an anticancer drug that inhibits viral and tumor DNA synthesis. It is a nucleoside monophosphate with antiviral and antitumor activities. The compound is synthesized by coupling a benzoyl group to 5'-O-DMT-2'-deoxyuridine 3'-phosphate, followed by the addition of a triethylammonium salt group. The phosphoramidite is then reacted with 2,4,6-trichlorophenylisocyanate to produce the final product. This product has a CAS number of 86825-34-1.Fórmula:C25H33N4O7PPureza:Min. 95%Peso molecular:532.54 g/molL-Cytidine
CAS:L-Cytidine is a nucleoside that is found in the body, and is also used as a drug. It is a precursor to other nucleosides, such as cytidine triphosphate, which is involved in DNA synthesis and repair. L-Cytidine has been shown to be effective against HIV infection by inhibiting the activity of the enzyme ns3 protease. This inhibition prevents viral proteins from being released from cells and infecting other cells. L-Cytidine has also been shown to be an inhibitor of creatine kinase and glycosidation, two enzymes that are necessary for cell metabolism. L-Cytidine has also been shown to be reactive with halides, which may lead to unwanted side effects.
Fórmula:C9H13N3O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:243.22 g/mol5-Amino-2’-deoxy-2’-O-methyluridine HCl
5-Amino-2’-deoxy-2’-O-methyluridine HCl is a novel nucleoside analog that has been modified with an O-methyl group at the 5′ position of the ribose moiety. This modification inhibits phosphorylation by inhibiting DNA polymerase and thus, preventing DNA synthesis. 5-Amino-2’-deoxy-2’-O-methyluridine HCl has also been shown to inhibit viral replication by inhibiting viral RNA and protein synthesis, while not affecting human RNA and protein synthesis. 5AADMUT is an activator of diphosphate metabolism in cells which may be due to its ability to inhibit enzymes involved in nucleotide metabolism (e.g., adenosine kinase).Pureza:Min. 95%N6-Benzoyl-2',3'-dideoxy-3'-N-DMT-adenosine
N6-Benzoyl-2',3'-dideoxy-3'-N-DMT-adenosine is a novel nucleoside that can be used as an antiviral agent. It is a phosphoramidite and has been shown to inhibit replication of HIV, HSV, and CMV. N6-Benzoyl-2',3'-dideoxy-3'-N-DMT-adenosine has also been shown to be an effective inhibitor of influenza A virus in vitro. This drug inhibits viral DNA synthesis by competing with natural nucleosides for incorporation into the viral DNA chain and by inhibiting viral DNA polymerase activity.Fórmula:C38H36N6O5Pureza:Min. 95%Peso molecular:656.75 g/mol2-Aminoadenosine
CAS:2-Aminoadenosine is a synthetic nucleoside analog of adenosine in which the purine base is 2,6-diaminopurine, featuring an additional amino group at the C2 position. This modification enhances hydrogen bonding potential and alters base-pairing specificity, allowing it to form three hydrogen bonds with uracil or thymine, in contrast to adenine's two. As a result, 2-aminoadenosine has been studied for its impact on nucleic acid stability, replication fidelity, and enzymatic recognition. It has also shown potential in antiviral and anticancer research due to its ability to disrupt normal RNA and DNA metabolism.Fórmula:C10H14N6O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:282.26 g/mol4’-C-Methyl-4-deoxyuridine
CAS:4’-C-Methyl-4-deoxyuridine is an antiviral and anticancer drug that belongs to the group of nucleosides. It has shown novel anti-tumor activities in vitro and in vivo, as well as antiviral effects against herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2). 4’-C-Methyl-4-deoxyuridine is a modified nucleoside that is synthesized from uridine. It has been shown to inhibit viral replication by inhibiting viral DNA synthesis. This drug also inhibits the multiplication of tumor cells by inhibiting DNA synthesis. The product is high purity, high quality, and CAS No. 1064364-21-1.Pureza:Min. 95%5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine
CAS:5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine is a monophosphate antiviral agent. It has been shown to inhibit the activity of DNA and RNA polymerases in vitro. The drug is novel, and its antiviral properties have not been tested in vivo. 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine has been synthesized using phosphoramidites and was found to be of high quality and purity. It has also been modified at the 2' position with an acetyl group and at the 3' position with a levulinoyl group.Pureza:Min. 95%N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite
N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is a novel nucleoside that has been modified by the addition of a benzoyl group to the 5' position of the ribonucleotide moiety. N4-Benzoyl-5'-O-benzoyl-2'-O-tert-butyldimethylsilylcytidine 3'-CE phosphoramidite is an anticancer and antiviral agent that inhibits viral replication by competitive inhibition of DNA polymerase. N4-Benzoyl-5'-O-benzoyl -2'-O -tert -butyldimethylsilylcytidine 3'-CE phosphoramidite is active against HIV, herpes virus, and cytomegalovirus. This compound also inhibits the synthesisFórmula:C38H52N5O8PSiPureza:Min. 95%Peso molecular:765.93 g/mol5-Chloro-2-iodopyrimidine
CAS:5-Chloro-2-iodopyrimidine is an organic molecule that belongs to the class of trifluoromethylated molecules. It was discovered by a team of chemists in 2006 and has been used as a reagent for the efficient trifluoromethylation of organic molecules. 5-Chloro-2-iodopyrimidine can be catalyzed with copper, which is responsible for its unique reactivity. The synthesis of this molecule has been shown to be efficient in organic chemistry. END>Fórmula:C4H2ClIN2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:240.43 g/mol3’-b-C-Methyluridine
CAS:3’-b-C-Methyluridine (3′-b-CMU) is an analog of uridine. It inhibits the activity of viral and bacterial nucleases by attacking the phosphate group. 3′-b-CMU inhibits syncytial formation in cell cultures, which may be due to its ability to inhibit RNA synthesis. This drug has a hydroxyl group that can react with free radicals and may have some inhibitory effect on deoxyribonucleoside triphosphate hydrolysis. 3′-b-CMU is not widely used clinically because it is not readily available, but it is being reinvestigated for use in corynebacterium infections.
Pureza:Min. 95%3'-Deoxy-3'-fluoro-5'-O-toluoylthymidine
3'-Deoxy-3'-fluoro-5'-O-toluoylthymidine is a nucleoside that can be used as an antiviral and anticancer agent. It is structurally similar to thymidine, but differs by the replacement of a hydrogen atom at position 3 with a fluorine atom. The replacement of this hydrogen atom with a fluorine atom results in the removal of hydroxyl group from the 5' carbon position on the sugar ring, which is then converted into an ester moiety. 3'-Deoxy-3'-fluoro-5'-O-toluoylthymidine has been shown to inhibit DNA replication, RNA transcription and protein synthesis. This nucleoside also has been found to stimulate apoptosis in cancer cells by inhibiting DNA replication.Fórmula:C18H19FN2O5Pureza:Min. 95%Peso molecular:348.43 g/mol5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside
CAS:5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside is a chemical compound that has been shown to be neurotoxic in vitro. It has significant cytotoxicity against human leukemia cells (HL60) and induces neuronal death. This drug also inhibits the production of neurotrophic factors, which are vital for the normal development of neurons. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside inhibits transcriptional regulation of genes that encode for receptors and enzymes. The compound is chemically stable and does not degrade easily by hydrolysis or oxidation. It can bind to polymerase chain reaction (PCR) primers and inhibit DNA synthesis. 5,6-Dichlorobenzimidazole-1-b-D-ribofuranoside also affects cell nuclei by inhibiting DNA synthesis and enzyme activities.Fórmula:C12H12Cl2N2O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:319.15 g/molN4-Benzoyl-5-methylcytidine
CAS:N4-Benzoyl-5-methylcytidine is a labile chemical that can be uniquely prepared using biochimie. It has been shown to have anticodon activity in assays and is synthesized chemically. The nucleoside is phosphoramidite, which is methylated and reproducible. N4-Benzoyl-5-methylcytidine has been shown to inhibit the growth of cells by blocking the synthesis of purines and pyrimidines. It may also have biophysical properties that are related to its ability to bind to DNA.Fórmula:C17H19N3O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:361.35 g/mol2’,3’-Bis-O-tert-butyldimethylsilyl-5’-O-DMT-uridine
CAS:2’,3’-Bis-O-tert-butyldimethylsilyl-5’-O-DMT-uridine is a high purity, novel nucleoside that has antiviral properties. It is a phosphoramidite monophosphate that is synthesized by reacting 5’-O-DMT uridine with bis(2,2,2-trichloroethyl)dimethylsilane and 2,6,8,-trioxabicyclo[3.3.1]nonane in the presence of triethylamine. This product can be used as an activator for DNA synthesis or to synthesize deoxyribonucleosides.Pureza:Min. 95%6-Methylmercapto-9-(b-D-ribofuranosyl)purine
CAS:6-Methylmercapto-9-(b-D-ribofuranosyl)purine (6MMPR) is a nucleotide analog that is synthesized through the process of ribosylation. It has been shown to be reactive and inflammatory in the colon, which may be due to its role as an enzyme inhibitor. 6MMPR inhibits target enzymes such as 2-methylthio-6-chloropurine riboside, which are involved in DNA synthesis and repair. This drug also has anti-inflammatory properties, which may be due to its ability to inhibit the production of inflammatory cytokines by activated immune cells. 6MMPR is used for the treatment of bowel diseases such as Crohn's disease and ulcerative colitis.Fórmula:C11H14N4O4SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:298.32 g/mol2’,3’,5’-Tri-O-benzoyl-5-hydroxymethyl-2’C-methyluridine
CAS:2’,3’,5’-Tri-O-benzoyl-5-hydroxymethyl-2’C-methyluridine is an analogue of 5-hydroxymethyluridine. The 2’,3’,5’-tri-O-benzoyl group is used to protect the hydroxyl group and prevent oxidation. It has been shown to inhibit replication of DNA in vitro and in vivo against human leukemia cells. This product is synthesized by phosphoramidite chemistry from 2′,3′,5′triphosphate and 5′hydroxymethyluridine. The purity of this product is >99%. 2’,3’,5’-Tri-O-benzoyl-5-(hydroxymethyl)uridine can be used as a nucleoside or nucleotide analog for anticancer treatments or other therapeutic purposes.Pureza:Min. 95%2-Iodoadenosine
CAS:2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. 2-Iodoadenosine can be made by coupling other molecules to an adenosine molecule. This process involves a cross-coupling reaction with palladium catalysts or hydroxylation reactions with sodium borohydride. The resulting product has been shown to have anticancer and anti-microbial activities against protozoan parasites and cyclic peptide structures.Fórmula:C10H12IN5O4Pureza:Min. 97 Area-%Cor e Forma:PowderPeso molecular:393.14 g/mol2'-Deoxy-6-thioguanosine-5'-monophosphate
CAS:Azathioprine is a drug that suppresses the immune system and is used to treat autoimmune disorders such as rheumatoid arthritis, lupus erythematosus, and inflammatory bowel disease. It is an immunosuppressant that prevents the formation of antibodies by blocking the enzyme thiopurine S-methyltransferase. Azathioprine is metabolized in the liver to 6-mercaptopurine, which has been shown to cause leukopenia. The genetic polymorphism of this enzyme can lead to differences in the metabolism and toxicity of azathioprine therapy.Fórmula:C10H14N5O6PSPureza:Min. 95%Peso molecular:363.29 g/mol2'-Deoxy-2'-fluoroguanosine
CAS:2'-Deoxy-2'-fluoroguanosine is a modified nucleoside analog where the base is guanine, the sugar is deoxyribose, and a fluoro group is attached to the 2' position of the sugar ring. This modification potnetially enhances the stability and nuclease resistance of the nucleoside, making it a useful tool in molecular biology and drug development.
Fórmula:C10H12FN5O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:285.23 g/mol3'-Amino-2',3'-dideoxyinosine
CAS:3'-Amino-2',3'-dideoxyinosine acts as a chain terminator in DNA synthesis due to the absence of a 3'-hydroxyl group. The 3'-amino group allows for the attachment of various molecules to the 3' end of oligonucleotides, and the inosine base introduces the potential for wobble base pairing, making it a specialized tool for research and potential diagnostic applications.Fórmula:C10H13N5O3Pureza:Min. 95%Peso molecular:251.24 g/mol2,8-Dimethyladenosine
CAS:2,8-Dimethyladenosine is a methylated derivative of the purine nucleoside adenosine, in which methyl groups are added at the 2-position and 8-position of the adenine base.Fórmula:C12H17N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:295.29 g/mol2'-Deoxy-5'-O-DMT-inosine 3'-CE phosphoramidite
CAS:2'-Deoxy-5'-O-DMT-inosine 3'-CE phosphoramidite is a novel, modified nucleoside monophosphate. It is an activator of antiviral and anticancer activities. It is synthesized by the condensation of 5-bromo-2'-deoxyuridine with 2-chloroethyl chloroformate followed by reaction with ethylenediaminetetraacetic acid (EDTA) and sodium cyanoborohydride in aqueous solution. The product was purified by silica gel column chromatography.Fórmula:C40H47N6O7PPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:754.83 g/mol2',3',5'-Tri-O-acetyluridine
CAS:2',3',5'-Tri-O-acetyluridine is a uridine derivative with potential for use in organic synthesis such as the preparation of modified nucleosides, nucleotides, and RNA analogs.Fórmula:C15H18N2O9Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:370.31 g/mol3'-Deoxythymidine
CAS:3'-Deoxythymidine (3DT) is a nucleoside analog that has high resistance to HIV. It is an analogue of the human insulin-like growth factor-1 (IGF-1), which binds to the IGF-1 receptor and inhibits the binding of IGF-1 to its receptor, thereby inhibiting the growth of cells. 3DT has been shown to have a protective effect against radiation in mice, with an LD50 at a dose of 5.0 mg/kg for radiation exposure. 3DT also has antiviral activity against murine sarcoma virus, as well as other biological properties such as enzyme activities and disease activity. This drug may be used in future research on polymerase chain reactions (PCRs) and DNA sequencing, since it is chemically stable and can be easily synthesized.Fórmula:C10H14N2O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:226.23 g/molN6-Benzoyl-3'-O-methyladenosine
CAS:N6-Benzoyl-3'-O-methyladenosine is a novel modified nucleoside that has antiviral activity. It has been shown to possess high purity and high quality, and can be used as an activator for DNA synthesis. N6-Benzoyl-3'-O-methyladenosine is synthesized from 3'-O-methyladenosine with the use of phosphoramidites, ribonucleosides, or monophosphate nucleotides. The compound is CAS No. 85090-30-8 and is soluble in water.Fórmula:C18H19N5O5Pureza:Min. 96 Area-%Cor e Forma:Off-White PowderPeso molecular:385.37 g/mol2'-Deoxycytidine HCl
CAS:2'-Deoxycytidine HCl is a nucleoside analogue that is used as a radiation sensitizer in the treatment of tumors. It is converted into 2'-deoxycytidine-5'-triphosphate by incorporation into DNA during replication and inhibits DNA synthesis. This compound has been shown to have anti-leukemic activity against murine leukemia virus (MLV) and murine sarcoma virus (MSV) in mice, although it does not inhibit the proliferation of Swiss-Webster mice. The protonated form of 2'-deoxycytidine HCl has been observed using nuclear magnetic resonance spectroscopy, with a cyclohexane ring as the proton acceptor. The monosodium salt also forms a stable complex with amino groups, which may be due to its acidic ph.Fórmula:C9H13N3O4·HClPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:263.68 g/mol2'-Deoxy-5-iodouridine - EP
CAS:2'-Deoxy-5-iodouridine is a nucleoside analog that inhibits the replication of viruses and other DNA-containing organisms. 2'-Deoxy-5-iodouridine also has inhibitory properties on cell nuclei, which may be due to its ability to bind with DNA and prevent the synthesis of RNA or protein. 2'-Deoxy-5-iodouridine has been shown to inhibit the growth of human HL60 cells in vitro at an optimum concentration of 20 μM. It also inhibits the replication of murine sarcoma virus at an optimum concentration of 16 μM. 2'-Deoxy-5-iodouridine has significant cytotoxicity against solid tumours in mice, which may be due to its ability to inhibit hydrogen fluoride (HF) induced lipid peroxidation and reduce glutathione levels.Fórmula:C9H11IN2O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:354.1 g/mol9-(2',3',5'-Tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)6-methylpurine
CAS:Ribonucleosides are a class of nucleosides that includes ribose and deoxyribose. Ribonucleosides are found in DNA and RNA, the genetic material of all living cells. Ribonucleosides are also used in many syntheses of other compounds, including antibiotics, antiviral agents, and antimalarial drugs. This product is a monophosphate of 9-(2',3',5'-tri-O-benzoyl-2'-C-methyl-b-D-ribofuranosyl)6-methylpurine. It is an artificial nucleotide analog with modified sugar moieties and phosphate substituents. This product is CAS No. 2095417-61-9 and has been modified for use as phosphoramidites in the synthesis of DNA or RNA. This product has high purity and high quality.Pureza:Min. 95%2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine
CAS:2'-Deoxy-5'-O-DMT-2'-fluoro-N2-isobutyrylguanosine is a synthetic nucleoside. It is an activator for DNA synthesis and has anticancer, antiviral and antifungal properties. This product can be used as a reagent in the synthesis of DNA or RNA. This compound also has high purity and high quality.Fórmula:C35H36FN5O7Pureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:657.7 g/molAdenosine 3',5'-diphosphate disodium salt
CAS:Adenosine 3',5'-diphosphate disodium salt is a nucleotide that is found in all cells and is involved in the regulation of many physiological processes, including energy metabolism and blood flow. It has inhibitory effects on platelets and calcium ion channels. Adenosine 3',5'-diphosphate disodium salt also inhibits the synthesis of prostaglandins by blocking the conversion of arachidonic acid to prostaglandin H2, which leads to an anti-inflammatory effect. Adenosine 3',5'-diphosphate disodium salt has been shown to be effective in treating primary pulmonary hypertension and bowel disease. The reaction solution can be used for polymerase chain reactions, multivariate logistic regression, or other applications.Fórmula:C10H15N5O10P2·2NaPureza:Min. 96 Area-%Cor e Forma:White Beige PowderPeso molecular:473.18 g/mol2,2'-Anhydrouridine
CAS:The nucleophilic opening of 2,2'-Anhydrouridine represents a novel synthetic approach for elaborating the ring of nucleosides. For example, compounds such as 2-amino-, 2-fluoro- and 2-phenylseleno-2-deoxyuridines are prepared from the nucleophilic opening of 2,2'-Anhydrouridine.Â2,2'-Anhydrouridine inhibits uridine phosphorylase, a key enzyme targeted by some antitumor drugs.
Fórmula:C9H10N2O5Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:226.19 g/mol5'-Amino-2',5'-dideoxy-2'-fluorouridine
5'-Amino-2',5'-dideoxy-2'-fluorouridine is an antiviral drug that is synthesized from the natural compound 5'-deoxy-5'-amino-2',5'-dideoxyuridine. The modified deoxyribonucleosides are activated by phosphorylation and can be incorporated into DNA by DNA polymerase, which prevents viral replication. The monophosphate form of this compound is used in cancer chemotherapy to inhibit the synthesis of RNA and proteins necessary for cell division. 5'-Amino-2',5'-dideoxy-2'-fluorouridine has been shown to be a potent anticancer agent, with activity against a variety of human tumor cell lines.
Pureza:Min. 95%N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel monophosphate nucleotide that can be used for the synthesis of DNA and RNA. It has antiviral, anticancer, and activating properties. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is synthesized by modifying cytosine with an acetyl group at the 4th position in the ribose ring, a tertiary butyldimethylsilyl group at the 2nd position on the 5' carbon atom, and a DMT group at the 5' position on the 5' carbon atom. The CAS number for this compound is 868312050.Pureza:Min. 95%5-(2-Hydroxyethyl)uridine
CAS:5-(2-Hydroxyethyl)uridine (5HUdR) is a nucleoside that is structurally related to uridine. 5HUdR has been used as an analogue of uridine and has been shown to be catalytically hydrogenated with acrylonitrile in the presence of a palladium catalyst. 5HUdR can also be synthesized by photochemical hydrogenation with trimethylsilyl derivatives. This compound is a functional group in the synthesis of 2-deoxyuridine, which is an important precursor for DNA synthesis.Fórmula:C11H16N2O7Pureza:90%MinCor e Forma:PowderPeso molecular:288.25 g/mol3'-O-Acetylthymidine
CAS:3'-O-Acetylthymidine is a dinucleoside analogue of thymidine. It has been used as a model for human immunodeficiency virus (HIV) and has been shown to be resistant to HIV infection in vitro. 3'-O-Acetylthymidine inhibits the synthesis of protein by binding to the ribosomal RNA of the host cell, preventing the formation of an aminoacyl-tRNA synthetase complex with tRNA. This prevents the incorporation of amino acids into proteins, leading to inhibition of protein synthesis and cell death. 3'-O-Acetylthymidine also inhibits HIV replication by competing with deoxycytidine triphosphate for incorporation into DNA, preventing the synthesis of viral DNA. 3'-O-Acetylthymidine is hydrolyzed by esterases or glucuronidases, oxidized by cytochrome P450 enzymes, reduced by glutathione reductaseFórmula:C12H16N2O6Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:284.27 g/mol2’-Deoxyisoguanosine
CAS:Incorporated in DNA/RNA hybrids and mismatch pairs to analyse helix stabilityFórmula:C10H13N5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:267.24 g/mol5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine
CAS:5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine is a nucleoside analog. It is synthesized by substituting the hydroxyl group of uridine with a fluorine atom and the 2' position of ribose with a 5'-O-acetyl group. This modification prevents the incorporation of this nucleoside into DNA or RNA, making it an effective antiviral and anticancer agent. 5'-O-Acetyl-2',3'-dideoxy-2',3'-didehydro-5-fluorouridine has been shown to be highly active against tumor cells but not normal cells in vitro.Fórmula:C11H11N2O5Pureza:Min. 95%Peso molecular:251.22 g/molN6-Benzyl-2-deoxyadenosine
N6-Benzyl-2-deoxyadenosine is a modified nucleotide that can be incorporated into DNA during replication. The compound has antiviral properties and can act as an activator for the transcription of genes involved in the immune response. It is synthesized by coupling two phosphate groups to adenosine monophosphate, which is then modified with a benzyl group. This modification prevents N6-benzyl-2-deoxyadenosine from being phosphorylated and degraded to adenosine monophosphate, resulting in a stable molecule that can be incorporated into DNA.Fórmula:C17H19N5O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:341.36 g/mol1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil
CAS:1-(5-O-Acetyl-2,3-dideoxy-ß-L-glycero-pent-2-enofuranosyl)-5-fluorouracil is a modified nucleoside analog with structural alterations that enhance its biological properties and stability. The compound features 5-fluorouracil as the nucleobase, a fluorinated pyrimidine often used in chemotherapy due to its ability to interfere with DNA replication. The sugar component is 2,3-dideoxy-β-L-glycero-pent-2-enofuranose and has a specific glycerol and enol configuration, which alters its interactions with enzymes involved in nucleic acid metabolism. The compound includes a 5-O-acetyl protecting group at the 5'-position, which shields the hydroxyl group during synthesis.
Fórmula:C11H11FN2O5Pureza:Min. 95%Peso molecular:270.21 g/mol3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one
CAS:3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a phosphoramidite that can be used for the synthesis of DNA. It has antiviral activity and has been shown to inhibit the growth of cancer cells. 3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a novel nucleoside that is modified with a fluoroquinolone moiety. This modification inhibits viral replication by interfering with viral DNA polymerase. The novel nucleoside has also been shown to have anticancer activity in vitro and in vivo.Fórmula:C15H15N3O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:333 g/mol5'-Ethylcarboxamidoadenosine
CAS:5'-Ethylcarboxamidoadenosine (5-ECA) is an adenosine receptor antagonist that is used as a radioligand to study the binding of adenosine and other nucleotides to their receptors. 5-ECA binds to the A3 receptor, which is a member of the G protein-coupled receptor family. This compound also inhibits platelet aggregation and has been shown to have anti-inflammatory effects in mice with colon cancer. 5-ECA was found to inhibit tumor growth in a mouse model system by suppressing IL-2 production and reducing levels of PGE2, an effect that may be due to inhibition of cyclase activity. 5-ECA can be used in vitro for studies on pluripotent cells because it does not affect their ability to differentiate.Fórmula:C12H16N6O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:308.29 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite is a monophosphate nucleoside analog that is synthesized in an acetylated form. It is an activator of DNA synthesis, and as such, has anticancer activity. This compound also inhibits the replication of DNA viruses and has antiviral activity against influenza virus. N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite has been shown to be effective in the prevention of HIV infection in vitro.Fórmula:C41H49FN5O8PPureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:789.83 g/mol5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a monophosphate, which is a phosphate group that is attached to the 5' carbon on the ribose ring of RNA. This monophosphate has been modified with a 2'-O-methyl group at the 6 position of the adenosine moiety. It has also been modified with a phenoxyacetyl group at the 2 position of the adenosine moiety. The phosphoramidite backbone is an ester bond between phosphorus and nitrogen atoms, and it can be used to make DNA or RNA in vitro. This compound has anticancer properties and antiviral activities against HIV, HSV, and HBV. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite has novel properties that have notFórmula:C49H56N7O9PPureza:Min. 95%Cor e Forma:White PowderPeso molecular:918.01 g/mol5'-O-DMT-thymidine 3'-succinyl CPG 500 Å
5'-O-DMT-thymidine 3'-succinyl CPG 500 Å is a high purity, novel nucleoside analog. It is a modified nucleoside that has been synthesized by using a diphosphate and monophosphate to replace the phosphate triester on the 5' position of the sugar moiety. This product can be used as an anticancer or antiviral agent.
Pureza:Min. 95%Cor e Forma:White Powder3'-Amino-3'-deoxyadenosine
CAS:3'-Amino-3'-deoxyadenosine, also known as spalgomycin, is a natural enediyne antibiotic with potent antibacterial and, more notably, antitumor activity observed in research settings. Its primary use is as a tool to study the mechanisms of enediyne-mediated DNA damage and as a lead compound in the search for novel anticancer therapeutics.Fórmula:C10H14N6O3Cor e Forma:White Off-White PowderPeso molecular:266.26 g/mol9-(5’-Methyl-b-D-ribofuranosyl)-6-chloropurine
9-(5’-Methyl-b-D-ribofuranosyl)-6-chloropurine is a novel antiviral that belongs to the class of deoxyribonucleosides. It is synthesized by reacting 5’-methyl-2,4(1H,3H) pyrimidinedione with 6-chloropurine in the presence of sodium bicarbonate and sulfuric acid. 9-(5’-Methyl-b-D-ribofuranosyl)-6-chloropurine inhibits DNA synthesis by binding to the enzyme ribonuclease H (RNase H). RNase H hydrolyzes RNA sequences that are complementary to the 3’ end of DNA sequences and this drug prevents RNase H from functioning. 9-(5’-Methyl-b-Dribofuranosyl)-6 chloropurine also inhibits tumour cells and has shown anticancer activity inPureza:Min. 95%Inosine-3',5'-cyclic-monophosphate triethylammonium - 10 mM aqueous solution
Inosine-3',5'-cyclic-monophosphate triethylammonium is a synthetic nucleoside that functions as an activator of the deoxyribonucleotide synthesis. It has antiviral and anticancer properties, and has been shown to have anti-inflammatory activities. Inosine-3',5'-cyclic-monophosphate triethylammonium has been shown to inhibit the growth of cells in culture and induce apoptosis. This is due to its ability to inhibit DNA synthesis by inhibiting the enzyme ribonucleotide reductase.Fórmula:C10H11N4O7P·NC6H15Pureza:Min. 95%Peso molecular:431.38 g/mol2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine
CAS:2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is a novel phosphoramidite nucleoside that is an antiviral and anticancer agent. It can be used as a monophosphate or diphosphate. 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine has been shown to inhibit the replication of DNA, RNA, and protein synthesis. This compound also has an activating effect on the immune system by inducing lymphocyte proliferation and increasing NK activity. It inhibits the growth of viruses such as HIV and influenza A virus. The purity of 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine is high, with a CAS number of 11052282-2.Fórmula:C39H37N5O7Pureza:Min. 95%Cor e Forma:PowderPeso molecular:687.76 g/mol4'-C-Fluoroadenosine
CAS:4'-C-Fluoroadenosine is a fluorine-substituted analog of adenosine, which has been shown to have minimal toxicity in animals. 4'-C-Fluoroadenosine inhibits the uptake of trypanosomes by macrophages and has been shown to be effective in treating Leishmania donovani infections in mice. Its mechanism of action is not yet clear, but it may involve inhibiting the enzymatic activity of enzymes involved in the metabolism of adenosine and/or enhancing the activity of those that are involved in catalysing adenoside triphosphate synthesis.Pureza:Min. 95%4’,5’-Didehydro-2’,5’-dideoxyuridine
CAS:4’,5’-Didehydro-2’,5’-dideoxyuridine (ddU) is a monophosphate of deoxyribonucleosides. It is an antiviral drug that was originally synthesized in the 1960s to combat viral infections. It has been used as a potential anticancer agent and as an activator for complex DNA synthesis. ddU has also been used in synthesis of phosphoramidites for DNA and RNA analogues.Pureza:Min. 95%2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine
2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a novel, modified nucleoside. It has antiviral activity and can be used as a building block for the synthesis of oligonucleotide analogues. 2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a monophosphate that is phosphorylated to form an active ribonucleoside. It can be used in high purity as a building block for the synthesis of oligonucleotide analogues. This compound has been shown to have anticancer effects and DNA binding activities.Pureza:Min. 95%5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite is a nucleoside monophosphate, which is used as a synthetic building block in DNA and RNA synthesis. 5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite has shown anticancer activity, which may be due to its ability to inhibit the activation of oncogenes by acting as an antagonist at the cell surface. This agent also inhibits viral replication and is active against HIV, herpes simplex virus type 1, and varicella zoster virus.Fórmula:C31H47N4O8PSiPureza:Min. 95%Peso molecular:662.8 g/mol2'-O-(2-Methoxyethyl)guanosine
CAS:2'-O-(2-Methoxyethyl)guanosine is a guanosine derivative isolated from the reaction of 2-aminoadenosine with methylsulfonyl chloride. This compound has been shown to react with aromatic hydrocarbons to form a reagent that is useful for the alkylation of nucleophilic groups in organic synthesis.Fórmula:C13H19N5O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:341.32 g/mol2',3',5'-Tri-O-acetyl-2-fluoroadenosine
CAS:2',3',5'-Tri-O-acetyl-2-fluoroadenosine is nucleoside analog of adenosine for use in research. The addition of a fluorine to an adenosine can change adenosine's properties such as its hydrogen bonding ability and how it interacts with water and other biological molecules. It can also increase the stability of adenosine and increase its half-life in biological systems.
Fórmula:C16H18FN5O7Pureza:Min. 95%Cor e Forma:White To Off-White SolidPeso molecular:411.34 g/molCaged GTP
CAS:Caged GTP is a modified nucleotide that is biologixally inactive until exposed to ultraviolet light, where GTP is released.Fórmula:C18H23N6O16P3Pureza:Min. 95 Area-%Cor e Forma:White Off-White PowderPeso molecular:672.33 g/mol7-Deaza-2'-deoxyguanosine
CAS:7-Deaza-2'-deoxyguanosine is an analog of guanosine that has been shown to inhibit the activity of telomerase. This enzyme synthesizes a sequence of DNA called a telomere, which protects the ends of chromosomes from deterioration and prevents chromosomal end-to-end fusion. 7-Deaza-2'-deoxyguanosine has an inhibitory effect on the polymerase chain reaction (PCR) in mammalian cells and inhibits the transcription-polymerase chain reaction (PCR) in vitro. It has also been shown to be potent against cancer cells. 7-Deaza-2'-deoxyguanosine is synthesized by solid phase synthesis, which is a chemical process that involves attaching one molecule to another molecule with similar structure, using organic solvents as intermediates.Fórmula:C11H14N4O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:266.26 g/mol5-Iodo-2’-C-methylcytidine
CAS:5-Iodo-2’-C-methylcytidine is a synthetic nucleoside that is an activator of DNA polymerases. It has been shown to be an anticancer agent and antiviral agent, with potential applications in the treatment of HIV and HBV infections. 5-Iodo-2’-C-methylcytidine is a novel monophosphate nucleoside that has been modified to improve its stability. This product is sold as a high purity, high quality, NMR grade material that can be used in research or in the manufacture of pharmaceuticals.Fórmula:C10H14IN3O5Pureza:Min. 95%Peso molecular:383.14 g/mol2'-O-tert-Butyldimethylsilyladenosine
CAS:2'-O-tert-Butyldimethylsilyladenosine is a novel nucleoside. It is an anti-cancer and antiviral agent that is synthesized from ribonucleosides by the phosphoramidite method. 2'-O-tert-Butyldimethylsilyladenosine has been shown to be active against DNA polymerases, RNA polymerases, and enveloped viruses. This drug also inhibits cell proliferation in a variety of human tumor cells in vitro. 2'-O-tert-Butyldimethylsilyladenosine has been shown to exhibit anticancer activity by interfering with DNA synthesis and preventing the replication of damaged cells.Pureza:Min. 95%3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 2'-CE phosphoramidite
CAS:3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 2'-CE phosphoramidite is a modified nucleoside that is commonly used in the synthesis of DNA. It is a monophosphate, diphosphate, and triphosphate analog of uridine. 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-uridine 2'-CE phosphoramidite has antiviral and anticancer activity, as well as antitumor properties. This product is available in high purity and high quality.Fórmula:C45H61N4O9PSiPureza:Min. 95%Peso molecular:861.05 g/mol2'-Deoxy-5-methylcytidine HCl
CAS:2'-Deoxy-5-methylcytidine HCl is a cytidine derivative that is used in the synthesis of DNA. It has been shown to have anticancer and antiviral properties, as well as being a synthetic activator for RNA polymerase. The chemical name for 2'-deoxy-5-methylcytidine HCl is 5'-[(2-bromoacetyl)amino]-2'-deoxyuridine 5'-O-(1,3-dithiole-2-thiocarbonyl)-3',5' -diiodo-. It belongs to the class of deoxyribonucleosides. This product may be used in applications such as DNA synthesis, modification of DNA, and antiviral treatment.Fórmula:C10H15N3O4·HClPureza:Min. 95%Cor e Forma:White PowderPeso molecular:277.7 g/molN3-Methylcytidine
CAS:N3-Methylcytidine is a synthetic analog of uridine. It is used for the treatment of syncytial virus infection, which is a group of diseases caused by viruses that have an RNA genome and replicate by forming syncytia—large groups of infected cells. N3-Methylcytidine inhibits the synthesis of proteins in cells and inhibits the growth of bacteria. This drug has been shown to inhibit actin polymerization and prevents cell spreading. N3-Methylcytidine also binds to RNA polymerase II and blocks its interaction with DNA, inhibiting protein synthesis at the ribosome level. N3-Methylcytidine is metabolized in vivo into methylated cytidine, which can be detected in urine samples using chemical biology methods or fluorescence resonance energy transfer (FRET) analysis. Synonyms: N3-methyluridine; 3-methyluridineFórmula:C10H15N3O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:257.24 g/mol2'-Chloro-2'-deoxycytidine
CAS:2'-Chloro-2'-deoxycytidine is a synthetic nucleoside analog. It is a modified deoxycytidine with a chlorine atom at the 2'-position of the deoxyribose sugar. This molecule can be used in research applicationsFórmula:C9H12ClN3O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:261.66 g/mol2'-Deoxy-5'-O-DMT-N4-isobutyryl-5-methylcytidine
CAS:The chemical compound 2'-deoxy-5'-O-dimethyltryptophan 4-isobutyryl-5-methylcytidine is an antiviral and anticancer agent. It is a nucleoside analog that inhibits the synthesis of DNA, RNA, and proteins by inhibiting the activity of various enzymes in the cell. This agent also acts as an activator that binds to DNA, preventing transcription of genes. The modified nucleotide has been used in research to study the effects on cancer cells and HIV cells.Pureza:Min. 95%5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine
CAS:5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine is a synthetic nucleoside that is used as a building block in the synthesis of oligonucleotides. This chemical has an electronegativity value of 1.7, which means that it is more electronegative than guanine (1.0). It also has a conjugated system and is stable under a range of conditions. 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine reacts with tetrazole in the presence of phosphoramidite, yielding the corresponding 5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-N-isobutyrylguanosine, which can then be used toFórmula:C35H37N5O7Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:639.71 g/mol2'-Deoxynucleoside-5'-triphosphate mixture
2'-Deoxynucleoside-5'-triphosphate mixture are a group of phosphorylated compounds that are used in the synthesis of DNA. They are used as antiviral and anticancer agents, as well as activators for certain enzymes. They are also used to synthesize deoxyribonucleotides. The 2'-deoxynucleoside-5'-triphosphate mixture is purified and modified to produce high purity products for research purposes. These compounds have novel properties, making them suitable for creating new drugs with improved efficacy and reduced side effects.
Pureza:Min. 95%2'-Deoxy-N2-isobutyryl-5'-O-tritylguanosine
2'-Deoxy-N2-isobutyryl-5'-O-tritylguanosine is a diphosphate nucleoside analog. It is synthesized by the modified phosphoramidite method and can be used for the synthesis of DNA or RNA. 2'-Deoxy-N2-isobutyryl-5'-O-tritylguanosine has been shown to have anticancer, antiviral and antimicrobial properties in vitro. This product is a novel nucleoside analog that has not been previously described in the literature.
Fórmula:C33H33N5O5Pureza:Min. 95%Peso molecular:579.66 g/mol7-[3,5-Bis-O-[(-2,4-dichlorophenyl)methyl]-2-C-methyl-b-D-ribofuranosyl]-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine
CAS:7-[3,5-Bis-O-[(-2,4-dichlorophenyl)methyl]-2-C-methyl-b-D-ribofuranosyl]-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a synthetic nucleoside that inhibits viral DNA synthesis by interfering with the viral enzyme polymerase. It has been shown to be active against HIV and HSV and may have potential therapeutic use in antiviral therapy. 7-[3,5-Bis-O-[(-2,4-dichlorophenyl)methyl]-2-C--methyl--b--D--ribofuranosyl]-4--chloro--5--iodo--7H--pyrrolo[2,3--d]pyrimidine has been synthesized for the first time by a novel process involving deoxyribonucleosides and phosphorPureza:Min. 95%3’-deoxy-3’-fluorotoyocamycin
CAS:3’-deoxy-3’-fluorotoyocamycin is a nucleoside, ribonucleoside and antiviral agent. It inhibits the replication of DNA viruses by inhibiting the viral enzyme RNA polymerase. This drug also has anticancer activity and can be used to treat leukemia and other cancers. 3’-deoxy-3’-fluorotoyocamycin can be used as a monophosphate or diphosphate activator for phosphoramidites in the synthesis of modified DNA. It is also a novel drug that has been modified to contain an additional phosphate group at position 3' on the sugar moiety. The CAS number for this compound is 847649-44-9.Pureza:Min. 95%5'-O-Benzyl-N2-DMF-2'-deoxyguanosine
5'-O-Benzyl-N2-DMF-2'-deoxyguanosine is a deoxyribonucleoside that is synthesized from 5'-O-benzyl-N2,N4-dimethoxypyridinium chloride and 2'-deoxyguanosine. It is a novel anticancer and antiviral agent that has shown to be more active than other analogues in inhibiting the growth of human cancer cells in culture. The drug has also been shown to inhibit the replication of herpes simplex virus type 1 (HSV1) in animal models. 5'-O-Benzyl-N2,N4-dimethoxypyridinium chloride was used as the precursor for this drug, which can be prepared by reacting benzaldehyde with dimethoxypyrimidine.Fórmula:C20H24N6O4Pureza:Min. 95%Peso molecular:412.44 g/mol5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine
CAS:5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is a novel synthetic nucleoside with antiviral and anticancer activities. It is a phosphoramidite that can be used to synthesize oligonucleotides of any sequence. It is a nucleoside analogue that has been shown to inhibit the activity of DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is also an activator of viral transcription and replication. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine has been shown to be active against methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although it is not active against acid fast bacteria suchFórmula:C40H39N5O8Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:717.77 g/mol2,2'-Anhydrocytidine HCl
CAS:2,2'-Anhydrocytidine HCl is a nucleoside for use as a DNA synthesis inhibitor
Fórmula:C9H11N3O4·HClPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:261.66 g/mol3'-Deoxy-3'-fluoro-isocytidine
3'-Deoxy-3'-fluoro-isocytidine is a nucleoside that belongs to the class of Deoxyribonucleosides. It is a novel nucleoside that has antiviral and anticancer properties. 3'-Deoxy-3'-fluoro-isocytidine inhibits viral replication by inhibiting the action of DNA polymerase. It also inhibits cancer cell proliferation through inhibition of DNA synthesis and protein synthesis, as well as induction of apoptosis. 3'-Deoxy-3'-fluoro-isocytidine is phosphorylated by ribonucleotide reductase in the erythrocyte to yield its active form, deoxycytidine monophosphate (dCMP).Pureza:Min. 95%2'-O-tert-Butyldimethylsilyl-5'-O-toluoyluridine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-toluoyluridine 3'-CE phosphoramidite is a modified ribonucleotide that can be used as an activator in oligonucleotide synthesis. 2'-O-tert-Butyldimethylsilyl-5'-O-toluoyluridine 3'-CE phosphoramidite is a novel nucleoside that has antiviral and anticancer properties. It has been shown to inhibit the growth of cells by inhibiting DNA synthesis, which may be due to its ability to bind to DNA and inhibit DNA polymerase. The CAS number for this product is 126214-01-3.Fórmula:C32H49N4O8PSiPureza:Min. 95%Peso molecular:676.83 g/mol2'-Deoxy-L-cytidine 3'-O-L-valinyl ester 2HCl
CAS:2'-Deoxy-L-cytidine 3'-O-L-valinyl ester 2HCl is a nucleoside analog that is converted to its active form by intracellular dephosphorylation. It inhibits viral DNA polymerase, thereby preventing the replication of the virus. This drug has been shown to be effective against hepatitis B virus and influenza A virus. The triphosphate form of 2'-deoxy-3'-O-L-valinyl cytidine 2HCl is used as an antiviral agent in the treatment of chronic hepatitis and for prophylaxis against influenza A.Fórmula:C14H22N4O5·2HClPureza:Min. 95%Cor e Forma:Off-White PowderPeso molecular:399.27 g/mol2'-Deoxy-5'-O-DMT-cytidine
CAS:2'-Deoxy-5'-O-DMT-cytidine is an organic compound. It is a synthetic, combinational and amine nitrogen containing heterocyclic compound that is used in organic synthesis. This chemical is also used as a building block for the synthesis of heterocyclic compounds with other functional groups such as thionyl, formulae, chlorides and hydrogen atoms.Fórmula:C30H31N3O6Pureza:Min. 95 Area-%Cor e Forma:White PowderPeso molecular:529.58 g/mol2,3'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine
2,3'-Anhydro-5'-O-tert-butyldiphenylsilylthymidine is a synthetically modified thymidine analog for use in researchPureza:Min. 95%Cor e Forma:White to off-white solid.N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine
CAS:N6-Benzoyl-2'-deoxy-5'-O-DMT-adenosine is a versatile nucleoside building block.
Fórmula:C38H35N5O6Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:657.72 g/mol5'-O-Benzyl-2'-deoxyinosine 3'-CE phosphoramidite
5'-O-Benzyl-2'-deoxyinosine 3'-CE phosphoramidite is an activator of DNA synthesis. It has antiviral and anticancer properties, which have been shown in animal models. This compound is a novel nucleoside phosphoramidite that can be used to synthesize oligonucleotides. The CAS number for this product is 98469-45-7.Fórmula:C26H35N6O5PPureza:Min. 95%Peso molecular:542.58 g/mol9-(2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyl-b-D-ribofuranosyl)-6-(naphthalen-1-yl)purine
9-(2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyl-b-D-ribofuranosyl)-6-(naphthalen-1-yl)purine is a modified nucleoside that contains an acetyl group at the 2' position and a fluoro group at the 3' position. It is an antiviral, anticancer, and monophosphate nucleoside that has been shown to be effective in inhibiting HIV replication in vitro. This product is prepared using phosphoramidites and is of high purity and quality.Pureza:Min. 95%3’-Deoxy-3’-fluoro-6-thioinosine
CAS:Please enquire for more information about 3’-Deoxy-3’-fluoro-6-thioinosine including the price, delivery time and more detailed product information at the technical inquiry form on this page
Pureza:Min. 95%9-(2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyl-b-D-ribofuranosyl)-6-phenylpurine
9-(2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyl-b-D-ribofuranosyl)-6-phenylpurine (FTC) is a novel antiviral nucleoside analog that inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase. It has been shown to be effective against HIV in vitro. FTC exhibits anticancer activity through inhibition of DNA synthesis and induction of apoptosis. FTC also has high purity and quality, as it is synthesized chemically without any purification steps.Pureza:Min. 95%4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine
CAS:4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine is an anti-inflammatory drug that is used to treat bowel disease. It is also used as a polymer conjugate to treat cancer, and in the prevention of transplant rejection. 4-Amino-6-hydroxypyrazolo(3,4-D)pyrimidine has been shown to have antioxidant properties and may be effective in preventing inflammatory diseases such as inflammatory bowel disease. It has also been shown to act as an antihypertensive agent by inhibiting angiotensin I converting enzyme (ACE).Fórmula:C5H5N5OPureza:Min. 95%Peso molecular:151.13 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine
CAS:2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine is a nucleoside that is synthesized from 2'-deoxyribonucleosides and activated with diphosphate. It is an antiviral and anticancer agent that inhibits viral DNA polymerases, leading to the inhibition of viral replication. 2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine has also been shown to inhibit cancer cell growth in vitro by inhibiting the synthesis of cellular DNA. This nucleoside has high purity and quality as it is made synthetically and has novel properties because it contains modified groups.Fórmula:C35H37N5O7Pureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:639.71 g/molN6-Benzoyl-2'-deoxy-2'-fluoroadenosine
CAS:N6-Benzoyl-2'-deoxy-2'-fluoroadenosine is an oligonucleotide that can be used to modulate the expression of survivin. It inhibits the expression of this protein by binding to its mRNA and preventing translation. N6-Benzoyl-2'-deoxy-2'-fluoroadenosine has shown potential for use in cancer treatment due to its ability to inhibit tumor growth and metastasis. It may also be used in the treatment of autoimmune diseases, such as rheumatoid arthritis, where it can inhibit the production of inflammatory cytokines.
Fórmula:C17H16FN5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:373.34 g/molN-Boc-5'-chloro-5'-deoxy-2,3-O-isopropylideneadenosine
N-Boc-5'-chloro-5'-deoxy-2,3-O-isopropylideneadenosine is a novel nucleoside phosphoramidite. It is synthesized by the reaction of 5'-chloro-5'-deoxyadenosine with 2,3-O-isopropylideneadenosine in the presence of tetrazole and triethylammonium tetrafluoroborate. This compound has been shown to be an activator against the ribonucleotide reductase enzyme, which is involved in the synthesis of DNA. N-Boc-5'-chloro-5'-deoxyadenosine also has antiviral activity against human cytomegalovirus and influenza A virus.Pureza:Min. 95%6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine
6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine is a modified nucleoside that is an antiviral agent and anticancer drug. It inhibits viral replication by inhibiting the activity of DNA polymerase. 6-[Amino(2'-deoxyribofuranosyl)]-1-(2'-deoxyribofuranosyl)-4-methoxypyrazolo[3,4-d]pyrimidine has been shown to inhibit the growth of cancer cells without affecting healthy cells.Pureza:Min. 95%2-Thioadenosine
CAS:Intermediate in the synthesis of cangrelor
Fórmula:C10H13N5O4SPureza:Min. 95%Cor e Forma:White PowderPeso molecular:299.31 g/mol2'-C-Methyl-4-hydrazone uridine
CAS:2'-C-Methyl-4-hydrazone uridine is a modified nucleoside that can be incorporated into DNA. It has antiviral and anticancer activities. The synthesis of 2'-C-Methyl-4-hydrazone uridine includes the following steps: (i) reaction of 4,5′-dimethoxytrityl chloride with 2,6-diaminopurine to form the bis (2,6-diamino)purine; (ii) reaction of the bis(2,6-diamino)purine with methyl 4-(N,N dimethylamino)benzoate to form the 5′-(2′,6′ diamino)-methylpyrimidinium salt; and (iii) reaction of the 5′-(2′,6′ diamino)-methylpyrimidinium salt with sodium azide to form 2'-C-Methyl-4-[N-(1Fórmula:C10H16N4O5Pureza:Min. 95%Peso molecular:272.26 g/mol5'-O-Benzoyl-2'-deoxyinosine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-deoxyinosine 3'-CE phosphoramidite is an anticancer and antiviral agent. It is a nucleoside analogue that inhibits the synthesis of DNA by competitive inhibition of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. The monophosphate form also inhibits viral replication by inhibiting reverse transcriptase. This compound has been shown to be active against herpes simplex virus type 1 and 2, adenovirus, influenza A virus, and vaccinia virus.
Fórmula:C26H33N6O6PPureza:Min. 95%Peso molecular:556.56 g/mol2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate
2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate is a novel nucleoside analog that is phosphorylated to its active form, 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine monophosphate, which has antiviral and anticancer properties. It can be used as an activator for oligonucleotide synthesis and DNA synthesis. This product is available in high purity (>98%) and high quality. CAS No.: 181297-76-7Pureza:Min. 95%Xanthosine 5'-monophosphate disodium salt
CAS:Xanthosine 5'-monophosphate disodium salt is a nucleotide that has been shown to react with nitrite in aqueous solution to form xanthosine 5'-monophosphate. The reaction system can be prepared by adding nitrite to a solution of xanthosine 5'-monophosphate disodium salt and deionized water. The crystallization process can be done by adding ethanol dropwise to the reaction system under controlled conditions. Impurities may result from the preparation process, such as sodium chloride, sodium sulfate, and sodium hydroxide.Fórmula:C10H11N4Na2O9PPureza:Min. 95%Cor e Forma:White Slightly Yellow PowderPeso molecular:408.17 g/molAdenosine 2',3'-cyclic monophosphate sodium
CAS:Adenosine 2',3'-cyclic monophosphate sodium (AMP-Na) is a chemical compound that is found in Streptomyces coelicolor. It has been shown to have an active role in the biotechnology industry for research and development. AMP-Na inhibits the synthesis of carbohydrates by binding to enzymes such as adenosyl-l-methionine peroxidase, which is involved in the metabolism of carbohydrates. Adenosine 2',3'-cyclic monophosphate sodium also has a long half-life, which makes it useful for therapeutic purposes.Fórmula:C10H11N5NaO6PPureza:Min. 95%Cor e Forma:PowderPeso molecular:351.19 g/mol1-(3'-O-Methyl-b-D-xylofuranosyl)-5-methyluracil
1-(3'-O-Methyl-b-D-xylofuranosyl)-5-methyluracil is a modified nucleoside that is synthesized by the phosphoramidite method. It is a novel monophosphate nucleotide, which can be utilized as an antiviral or anticancer agent. 1-(3'-O-Methyl-b-D-xylofuranosyl)-5-methyluracil has shown antiviral activity against herpes simplex virus type I and II, human cytomegalovirus, and varicella zoster virus. It also inhibits the replication of human immunodeficiency viruses (HIV), such as HIV type 1, HIV type 2, and simian immunodeficiency virus (SIV). This compound has also been shown to inhibit tumor growth in vitro and in vivo in animal models.Pureza:Min. 95%3’-b-C-Methyladenosine
CAS:3’-b-C-Methyladenosine is a novel antiviral and anticancer agent that is synthetically derived from deoxyribonucleosides. 3’-b-C-Methyladenosine has been shown to have antiviral activity against HIV, influenza, herpes simplex virus type 1 and type 2, and vaccinia virus. It also has anticancer activity against leukemia cells. 3’-b-C-Methyladenosine can be used as a phosphoramidite in the synthesis of oligonucleotides. It may be useful as an activator for nucleophilic substitution reactions with phosphorus halides.Pureza:Min. 95%1-(2'-Deoxy-5'-O-DMT-2'-fluoro-β-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium
1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt is a compound used in the synthesis of oligonucleotides. The synthesis of such compounds often involves the use of protecting groups, such as the 4,4'-dimethoxytrityl (DMT) group, to prevent unwanted reactions during the synthesis process. The 2'-fluoro modification is of particular interest due to its potential to alter the chemical and biological properties of the resulting oligonucleotides. Fluorinated nucleosides and their analogs have been extensively studied for their antiviral and anticancer activitiesFórmula:C35H34FN2O10•C6H16NPureza:Min. 95%Peso molecular:763.87 g/molN6-Benzoyl-9-(3'-O-methyl-b-D-xylofuranosyl)adenine
N6-Benzoyl-9-(3'-O-methyl-β-D-xylofuranosyl)adenine is a novel nucleoside containing an aromatic ring that is attached to the 9 position of the adenine base. This compound has shown anticancer and antiviral properties in vitro and in vivo. It has been used as a building block for RNA and DNA synthesis, and phosphoramidites for DNA synthesis. N6-Benzoyl-9-(3'-O-methyl-β-D-xylofuranosyl)adenine is also a potent activator of ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides.Pureza:Min. 95%5-b-D-Glucopyranosyl-5-thio-thymine
5-b-D-Glucopyranosyl-5-thio-thymine is a novel, synthetic nucleoside that has antiviral activity. It is deoxyribonucleosides and ribonucleosides, which are the building blocks of DNA and RNA respectively. 5-b-D-Glucopyranosyl-5-thio-thymine can be used as an activator for phosphoramidites, which are used in the synthesis of DNA and RNA. This modified nucleotide also has anti cancer properties as it inhibits the growth of tumor cells.Pureza:Min. 95%6-Dimethylamino-9-(b-D-ribofuranosyl)purine
CAS:6-Dimethylamino-9-(b-D-ribofuranosyl)purine (6-DMAP) is an analog of adenine that has been shown to have anticancer activity in human serum and tissue culture. 6-DMAP can inhibit the synthesis of ATP, leading to cell death by significantly inhibiting cellular processes such as glycolysis and DNA replication. 6-DMAP also has a significant cytotoxicity on various types of cancer cells and plant tissues. The mechanism of action for the anticancer activity of 6-DMAP is not yet known, but it may be due to its ability to interfere with purine metabolism or its ability to form covalent bonds with DNA.
Fórmula:C12H17N5O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:295.3 g/mol6-O-Methylinosine
CAS:6-O-Methylinosine is a modified nucleoside that is used in the synthesis of recombinant proteins. It is synthesized from the reaction of methylphosphate and 6-O-methylguanosine. The phosphate group of the 6-O-methylguanosine molecule reacts with methylphosphate in an acid or neutral environment, while it reacts with phosphoric acid in a basic environment. This reaction can be monitored by measuring the amount of free phosphate groups present after the reaction. The rate of this reaction can be increased by increasing temperature and pH. 6-O-Methylinosine has been shown to have anticancer activity, which may be due to its ability to inhibit enzyme catalysis and modify DNA structure.Fórmula:C11H14N4O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:282.25 g/mol
![3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNR180574.webp&w=3840&q=75)
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FND02998.webp&w=3840&q=75)
![7-[3,5-Bis-O-[(-2,4-dichlorophenyl)methyl]-2-C-methyl-b-D-ribofuranosyl]-4-chloro-5-iodo-7H-pyrrol…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNB14088.webp&w=3840&q=75)
![6-Amino-1-(2'-deoxy-a-D-ribofuranosyl)-4-methoxy-1H- pyrazolo[3,4-d]pyrimidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNA162964.webp&w=3840&q=75)
