Nucleosídeos

Pyrimidine nucleobase; allosteric regulator and coenzyme for reactions

P2Y receptor agonist; precursor in RNA biosynthesis

3'-Azido-2',3'-dideoxyuridine is an analog of the nucleoside dideoxyuridine that inhibits HIV replication. It has a high inhibitory dose and low toxicity. 3'-Azido-2',3'-dideoxyuridine is converted to its active form, 3'-azido-2',3'-dideoxythymidine (AZT), by dephosphorylation in human serum. AZT inhibits HIV replication by competing with the natural substrate for viral DNA polymerase, thereby inhibiting synthesis of viral DNA. 3'-Azido-2',3'-dideoxyuridine has been shown to be effective against hepatitis B virus and hepatitis C virus in cell cultures.

4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine is a novel nucleoside analog that can be activated to the monophosphate form for incorporation into DNA. It has antiviral and anticancer properties. 4'-C-Azido-2'-deoxy-2'-fluoro-b-D-arabinouridine has been shown to inhibit the proliferation of cultured tumor cells, suggesting a potential use in cancer chemotherapy.

4',5'-Didehydro-5'-deoxy-2'-O-methyluridine is a novel nucleoside phosphoramidite. It is a monophosphate, high purity and high quality. 4',5'-Didehydro-5'-deoxy-2'-O-methyluridine is an activator of DNA polymerase and can be used in the synthesis of DNA. 4',5'-Didehydro-5'-deoxy-2'-O-methyluridine also has antiviral properties and can be used to synthesize deoxyribonucleosides. It has been modified to have a diphosphate group at the 5' end, which allows it to be incorporated into DNA during synthesis.

7-Deaza-2'-deoxy-O6-methylguanosine is a novel nucleoside phosphoramidite that is the first of its kind to have been shown to be an antiviral agent. It is also anticancerous and stimulates diphosphate synthesis. 7-Deaza-2'-deoxy-O6-methylguanosine is a highly reactive nucleoside phosphoramidite that reacts with DNA in the same manner as deoxyribonucleotides. The monophosphate form of this compound has been shown to be anticancerous and stimulate diphosphate synthesis. This novel compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in vitro.

2'-Deoxy-2',2'-difluorouridine 5'-triphosphate triethylammonium salt is a synthetic nucleoside which is an activator of deoxyribonucleoside monophosphates and diphosphates. This compound has antiviral, anticancer and antimicrobial properties. It is a novel nucleoside that has not been previously reported. This product is high purity, high quality, and CAS No.

2’,3’,5’-Tri-O-(tert-butyldimethylsilyl)-adenosine is a novel nucleoside that is synthetically modified by the replacement of the ribose sugar with an amino sugar. The modification of the sugar reduces the likelihood of hydrolysis to ribose and phosphate. This product has shown anticancer effects against human tumor cells in vitro and in vivo. It also has antiviral activities against herpes simplex virus type 1 (HSV-1). 2’,3’,5’-Tri-O-(tert-butyldimethylsilyl)-adenosine is a monophosphate nucleoside that inhibits DNA synthesis by inhibiting DNA polymerase. It acts as a competitive inhibitor for deoxyribonucleotides and phosphoramidites, which are used in DNA synthesis. 2’,3’,5’-

3'-Deoxy-N6-lauroyladenosine is a nucleoside analog that is used to treat cancer. It is a phosphoramidite compound and it has been shown to be highly active against cancer cells. 3'-Deoxy-N6-lauroyladenosine is an antiviral agent that inhibits viral DNA synthesis by competing with the natural substrate, deoxyribonucleosides, for incorporation into the growing DNA chain. It also prevents the replication of RNA viruses by inhibiting their transcription and translation processes. 3'-Deoxy-N6-lauroyladenosine also inhibits inflammation in the body and may act as a chemotherapeutic agent in other diseases such as diabetes, Alzheimer's disease, and Parkinson's disease.

5-Bromo-2,4-di(benzyloxy)pyrimidine is an activator of DNA and RNA synthesis. It is a phosphoramidite that is used in the synthesis of oligonucleotides. 5-Bromo-2,4-di(benzyloxy)pyrimidine has antiviral activity and can inhibit the replication of HIV in vitro. This compound also has anticancer activity when it is given as a monophosphate, while its diphosphate form inhibits DNA and RNA synthesis. 5-Bromo-2,4-di(benzyloxy)pyrimidine can be synthesized from 2,4-dibenzyloxy pyrimidine and bromine in high purity with a CAS number 41244-53-5.

2-Amino-6-chloro-4-methoxypyrimidine (2ACMP) is a molecule that has been synthesized by the process of asymmetric synthesis. It is soluble in ethyl formate and has shown to be a strong inhibitor of the enzyme uv absorption, with an inhibition constant of 1.0 x 10 M. 2ACMP has been shown to inhibit molecular processes such as vibrational excitation, molecular modeling, and surface methodology. This molecule also binds to metal hydroxides and can be used for process optimization when combined with solubility data and nutrient solutions.

6-Azathymidine is an antiviral agent that prevents the synthesis of viral DNA. It is a nucleoside analogue that contains a hydroxyl group at the 6 position on a pyrimidine ring. This compound has been shown to be effective in treating HIV infection and cancer, as well as herpes simplex virus and influenza virus. 6-Azathymidine inhibits the enzyme ribonucleotide reductase, which is responsible for converting ribonucleotides into deoxyribonucleotides, thereby blocking DNA synthesis. The phosphate derivatives of this drug have been shown to inhibit the biosynthesis of human immunodeficiency virus (HIV) by interfering with intermolecular hydrogen bonding between guanine and adenine.

2',5'-Dideoxy-8,5'-cycloadenosine is an anticancer nucleoside. It is a modified deoxyribonucleoside that contains a 2'-deoxyribose sugar with a ribose sugar at the 5' position. This product has been shown to be active against DNA and RNA viruses in the lab. It also has antiviral properties and can inhibit the synthesis of DNA, RNA, or both. The chemical structure of this product is novel and has not been found in nature.

2'-C-Methylinosine is an analog of 2'-deoxyinosine that is used as a prodrug for the treatment of hepatitis B virus infection. It has been shown to inhibit RNA synthesis in cell cultures by competitively inhibiting the activity of rna-dependent RNA polymerase. This inhibition leads to the accumulation of unprocessed, inactive ribonucleotides, which are eventually degraded by cellular enzymes. 2'-C-Methylinosine is an analog of 2'-deoxyinosine that has been modified at the C2 position with methyl groups (hence its name). The modification increases the stability and solubility of this molecule. Clinical trials have shown that 2'-C-Methylinosine can be used to treat hepatitis B virus infection when combined with other drugs such as lamivudine or entecavir.

4-Chloro-5-fluoropyrimidine is a fluoropyrimidine that is used in the synthesis of pharmaceuticals, such as 4-amino-2-chloro-5-fluoropyrimidine. This compound is synthesized by chlorinating 4-chloro-5-fluoropyrimidine with chlorine gas. The resulting product is hydrolyzed to yield 4-amino-2,4,5,6 tetrafluoro pyrimidines. 4CFP can also be obtained by hydrogenolysis of toluene with chlorine gas and sodium hydroxide or hydrolyzing an ammonium salt with hydrochloric acid.