
Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3567 produtos de "Nucleosídeos"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
2'-Deoxy-5'-O-DMT-2'-fluoro-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
<p>2'-Deoxy-5'-O-DMT-2'-fluoro-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a modified nucleoside that has been shown to inhibit the growth of cancer cells. It is synthesized by the reaction of 2'-deoxy-5'-O-dimethoxytriphenylmethyl adenosine 3'-chloroethylphosphoramidite and 2',6' -difluoroaniline in an organic solvent. The product is purified by silica gel column chromatography, followed by recrystallization from a mixture of methanol and water. This novel nucleoside may prove to be a useful anticancer agent as it inhibits the growth of cancer cells without producing any apparent toxicity for normal cells.</p>Pureza:Min. 95%2'-Deoxy-N2-isobutyryl-3'-O-levulinoylguanosine
CAS:<p>2'-Deoxy-N2-isobutyryl-3'-O-levulinoylguanosine is a monophosphate antiviral agent that inhibits the synthesis of viral RNA by blocking the activity of DNA polymerase. It has been shown to be active against Herpes simplex virus type 1 and 2 (HSV1, HSV2) and cytomegalovirus (CMV). This compound also has anticancer activity due to its ability to inhibit cell proliferation and induce apoptosis in cancer cells. The antiviral activity of 2'-deoxy-N2-isobutyryl-3'-O-levulinoylguanosine is not limited to herpes viruses and also includes HIV, human T lymphotropic virus type I (HTLV1), and human cytomegalovirus. This product is synthesized with high purity, high quality, and high yield.</p>Fórmula:C19H25N5O6Pureza:Min. 95%Peso molecular:419.44 g/mol(+)-Emtricitabine
CAS:<p>Emtricitabine is a synthetic nucleoside analog of cytidine. It is used in the treatment of HIV infection and hepatitis B virus infection. Emtricitabine binds to human DNA polymerase, preventing the incorporation of viral DNA into the host cell's genome. This prevents the virus from multiplying and reproducing, thereby inhibiting the spread of HIV in humans. The drug has been shown to inhibit replication at all stages of HIV-1, including reverse transcription and integration into host cell DNA. Emtricitabine also inhibits replication of other viruses such as herpes simplex virus type 1 (HSV-1) and hepatitis C virus (HCV). Emtricitabine is a prodrug that must be activated by phosphorylation before it can be incorporated into DNA. This activation requires tenofovir alafenamide hemifumarate as an activator, which is an experimental drug with improved bioavailability, reduced renal clearance, and</p>Fórmula:C8H10FN3O3SPureza:Min. 95%Peso molecular:247.25 g/molU-13C10, U-[15N2]-mono-Labelled Thymidylyl-3'-5'-thymidine ammonium (compound A)
<p>U-13C10, U-[15N2]-mono-Labelled Thymidylyl-3'-5'-thymidine ammonium (compound A) is a novel anticancer drug that is synthesized by phosphoramidite chemistry. It is an activator of DNA synthesis and has been shown to be cytotoxic against cancer cells in vitro. This compound is also a high quality nucleoside analogue. The molecular weight of this compound is 434.4 g/mol and it has a CAS number of 81633-09-9.</p>Fórmula:C20H30N5O12PPureza:Min. 95%Peso molecular:563.45 g/mol5'-Ethylcarboxamido-2',3'-O-isopropylideneadenosine
CAS:<p>5'-Ethylcarboxamido-2',3'-O-isopropylideneadenosine is an activator that can be used to treat cancer. It is synthesized from the natural amino acid inosine by replacing the amine group with ethyl carboxamide. The synthesis of this molecule is currently in progress. This product has shown anticancer activity and antiviral effects, as well as high purity and novel properties.</p>Fórmula:C15H20N6O4Pureza:Min. 95%Peso molecular:348.36 g/mol2'-TFA-NH-dA
CAS:<p>2'-TFA-NH-dA is a monophosphate nucleotide. It is a novel and modified ribonucleoside that can be used as an activator to promote the synthesis of diphosphate, deoxyribonucleosides, and phosphoramidites. 2'-TFA-NH-dA has been shown to have anticancer properties in vitro and antiviral properties in vivo. This compound is synthesized from 2'-deoxyadenosine 5'-phosphate (2'-DAP), which is obtained from the amino acid ATP.</p>Fórmula:C12H13F3N6O4Pureza:Min. 95%Peso molecular:362.26 g/molBiotin-11-2-deoxyuridine-5-triphosphate tetralithium salt
CAS:<p>Biotin-11-2-deoxyuridine-5-triphosphate tetralithium salt is a modified nucleoside that is used in antiviral and anticancer treatments. The deoxyribonucleosides are synthesized by coupling biotin to 2'-deoxyuridine 5'-triphosphate, which is then reacted with lithium tetralithium chloride. This product has been shown to be an activator of DNA synthesis and can induce the proliferation of cancer cells. Biotin-11-2-deoxyuridine-5-triphosphate tetralithium salt has been shown to inhibit the growth of both human immunodeficiency virus (HIV) and murine leukemia virus (MLV).<br>Biotin-11-2-deoxyuridine-5-triphosphate tetralithium salt is also used in the synthesis of ribonucleosides for use in DNA research. It</p>Fórmula:C24H41N6O17P3S·4LiPureza:Min. 95%Peso molecular:886.41 g/molThymidine 5'- triphosphate lithium salt - 100mM aqueous solution
CAS:<p>Thymidine 5’-triphosphate tetralithium salt (dTTP) is a crucial component in chemical biology research. It is a modified form of thymidine, containing three phosphate groups. Important in DNA replication and repair, dTTP acts as a substrate for DNA polymerases during polymerase chain reactions (PCR), facilitating the amplification of specific DNA sequences. In addition, in DNA sequencing, dTTP is incorporated into newly synthesized DNA strands, allowing precise determination of nucleotide sequences.</p>Fórmula:C10H17N2O14P3·xLiPureza:Min. 95%Peso molecular:482.17 g/mol6-Bromo-4-chloropyrido[2,3-d]pyrimidine
CAS:<p>6-Bromo-4-chloropyrido[2,3-d]pyrimidine is a pyrimidine derivative that has been synthesized using cyclization and condensation techniques. The synthesis of this compound is efficient and uses relatively low amounts of starting materials. It can be made using microwave irradiation in a high yield. 6-Bromo-4-chloropyrido[2,3-d]pyrimidine is an aromatic ring with efficient methods for synthesis and bromination. This research could be used to produce new compounds with similar structures that are more potent than current drugs.</p>Pureza:Min. 95%Fluorescein-dt cep
CAS:<p>Fluorescein-dt cep is a monophosphate nucleoside analog that is modified with an activated ester group. It is used as a prodrug for the treatment of influenza in humans. Fluorescein-dt cep has antiviral activity, which may be due to its ability to inhibit viral RNA synthesis. This agent also has anticancer activity and has been shown to kill leukemia cells by interfering with DNA synthesis. The chemical name for fluorescein-dt cep is 1-(2,6-dichloro-4-(5,7-dimethoxy-4-methylpyridiniumyl)phenyl)cytosine monophosphate. Fluorescein-dt cep is also known by the following synonyms: 1-(2,6-Dichloro-4-(5,7-dimethoxyquinoliniumyl)phenyl)-1H-[1,3]diox</p>Fórmula:C79H89N6O17PPureza:Min. 95%Peso molecular:1,425.6 g/mol2'-Deoxy-5'-O-DMT-5-D-uridine 3'-CE phosphoramidite
Produto Controlado<p>2'-deoxy-5'-O-DMT-5-D-uridine 3'-CE phosphoramidite (2'DMTU) is a synthetic nucleoside with anticancer, antiviral and antiretroviral activity. 2'DMTU is a ribonucleotide monophosphate that can be used to modify RNA in the laboratory. It is a modified nucleoside that prevents RNA polymerase from adding onto the DNA strand and has been shown to activate apoptosis in cells that are resistant to anticancer drugs.</p>Fórmula:C39H46N4O8PDPureza:Min. 95%Peso molecular:731.81 g/mol5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil
CAS:<p>5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-5'-O-acetyl-b-L-ribofuranosyl)-uracil is a modified nucleoside that is phosphorylated and activated to 5'-triphosphate. It has antiviral, anticancer, and antimalarial activities.</p>Fórmula:C11H12N2O5Pureza:Min. 95%Peso molecular:252.22 g/mol5-Amino-1-(b-D-ribofuranosyl)imidazole-4-carboxamide-5'-phosphate
<p>5-Amino-1-(b-D-ribofuranosyl)imidazole-4-carboxamide-5'-phosphate is a ribonucleoside monophosphate. It is an antiviral agent that inhibits the synthesis of RNA by preventing the attachment of ribonucleotides to the 5' end of RNA. This drug is also used in anticancer therapy, as it has been shown to inhibit DNA synthesis and induce cell differentiation. 5-Amino-1-(b-D-ribofuranosyl)imidazole-4-carboxamide-5'-phosphate is synthesized from 1-(2'-deoxyribofuranosyl)-5-(2'-deoxyribofuranosyl)imidazole, which can be made from 2,4,6,-triaminopyrimidine and 2,3,-dideoxyribose. This product has CAS number 13</p>Pureza:Min. 95%5-Methoxyuridine 5′-triphosphate sodium, 85mM/L aqueous solution
CAS:<p>Please enquire for more information about 5-Methoxyuridine 5′-triphosphate sodium, 85mM/L aqueous solution including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C10H17N2O16P3•NaxPureza:Min. 95%N6-Benzoyl-5'-O-DMT-2'-O-(2-Ethoxy-2-oxoethyl)adenosine
<p>N6-Benzoyl-5'-O-DMT-2'-O-(2-Ethoxy-2-oxoethyl)adenosine is a phosphoramidite that is used in the synthesis of oligonucleotides. It is an activator of ribonucleotides and diphosphate for RNA synthesis. Its high purity and quality make it suitable for use in the synthesis of DNA, RNA, or other nucleoside analogues.</p>Pureza:Min. 95%3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine
CAS:<p>3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine is a nucleoside that acts as an activator and phosphoramidite. The di-O-benzoyl group is used to protect the 2'-hydroxyl group during the synthesis of oligonucleotides. 3',5'-Di-O-benzoyl-5-fluoro-2'-O-methyluridine has been shown to have anticancer activity against human breast cancer cells. It also inhibits the replication of DNA viruses, such as HIV, hepatitis B virus and herpes simplex virus type 1, and is active against influenza A virus. This compound has also been shown to inhibit the production of inflammatory cytokines in vitro.</p>Fórmula:C24H21FN2O8Pureza:Min. 95%Peso molecular:484.44 g/molTFA-ap-dU
CAS:<p>TFA-ap-dU is a modified, ribonucleosides that are used in DNA synthesis. The polymerase chain reaction (PCR) technique can be used to generate a large number of copies of a specific sequence of nucleotides from the original DNA template. This product is used for antiviral and anticancer research. TFA-ap-dU has been shown to be effective against Hepatitis B virus and Human Immunodeficiency Virus (HIV). It is also an activator of DNA and RNA synthesis.</p>Fórmula:C14H14F3N3O6Pureza:Min. 95%Peso molecular:377.27 g/mol2-Chloro-3-deazaadenosine
CAS:<p>2-Chloro-3-deazaadenosine is an antiviral drug that inhibits the synthesis of DNA by acting as a competitive inhibitor for adenosine. It has been shown to be effective in the treatment of hepatitis B virus and herpes simplex virus infections. 2-Chloro-3-deazaadenosine prevents the incorporation of the natural nucleoside adenosine into DNA, which leads to inhibition of viral replication and cell division. This drug also has been shown to inactivate liver cells in bovines, which may account for its toxicity. The synthesis of 2-chloroadenosine is difficult and laborious due to its glycosylation, making it more expensive than other analogues that are more easily synthesized.</p>Fórmula:C11H13ClN4O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:300.7 g/mol5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine 3'-CE phosphoramidite
<p>5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine 3'-CE phosphoramidite is a high purity, diphosphate, Anticancer, Modified, Phosphoramidites, DNA, High quality, Novel, Activator. It is CAS No. 106433-85-6 and has the molecular formula C15H14N4O8P. 5'-O-DMT-2'-O-(2-methylacetamido)-5-methyluridine 3'-CE phosphoramidite is not found in nature. This product is a monophosphate nucleoside that belongs to the group of nucleosides and deoxyribonucleosides. It can be used for synthesis of DNA and RNA, as well as for the treatment of cancer cells.</p>Pureza:Min. 95%N6-Benzoyl-3'-O-benzoyl-2'-deoxyadenosine
<p>6-Benzoyl-3'-O-benzoyl-2'-deoxyadenosine (BBD) is a synthetic nucleoside that has antiviral activity. It is an activator of DNA polymerase and also a novel monophosphate nucleotide. BBD has been shown to inhibit the replication of RNA in cells infected with HIV and HSV.</p>Pureza:Min. 95%5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite
<p>5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite is a high purity, modified nucleoside with anticancer potential. It is an activator of DNA synthesis and inhibits the growth of tumor cells. This chemical is a monophosphate or diphosphate, depending on the conditions used in synthesis. 5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite is used to synthesize DNA, RNA, and deoxyribonucleosides. It is also used as a precursor for other ribonucleosides and nucleotides that are needed in the synthesis of DNA and RNA.<br>5'-O-DMT-4-methoxythymidine 3'-CE phosphoramidite can be synthesized from commercially available starting materials such as 4-(2-deoxyribofuranosyl)thymidine, 5-(3,</p>Fórmula:C41H51N4O8PPureza:Min. 95%Peso molecular:758.86 g/mol2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-Me phosphoramidite
<p>2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-Me phosphoramidite is a novel nucleoside analog with antiviral and anticancer activities. It inhibits viral replication by inhibiting the viral polymerase and cellular DNA polymerases. 2'-Deoxy-5'-O-DMT-N6-phenoxyacetyladenosine 3'-Me phosphoramidite also inhibits tumor growth by arresting cells in the G2/M phase of the cell cycle. This compound has been shown to be effective against human leukemia, lymphoma, breast cancer, and colon cancer cells.</p>Fórmula:C46H53N6O8PPureza:Min. 95%Cor e Forma:SolidPeso molecular:848.94 g/mol3,4-Dihydro-3-oxo-4-b-D-ribofuranosyl-2-pyrazinecarboxamide
CAS:<p>3,4-dihydro-3-oxo-4-(2-pyrimidinyl)-2,5-dioxopyrrolidine carboxamide is an analog of acyclovir that has antiviral activity against a variety of viruses. It binds to the receptor binding site on the virus and prevents viral replication. 3,4-Dihydro-3-oxo-4-(2-pyrimidinyl)-2,5-dioxopyrrolidine carboxamide is effective against human influenza A virus (H1N1) and hepatitis B virus. This drug also has been shown to inhibit the growth of phlebovirus in cell culture by preventing the synthesis of viral RNA.</p>Fórmula:C10H13N3O6Pureza:Min. 95%Peso molecular:271.23 g/molN6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine
CAS:<p>N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is an activator nucleoside that is used as a phosphoramidite in DNA synthesis. It is also used in antiviral and anticancer therapies. N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine has been shown to have high purity and high quality, making it suitable for use in the pharmaceutical industry. This product is not active against bacterial or viral infections, but has proved to be effective in the treatment of leukemia, lymphoma and other cancers.</p>Fórmula:C38H34FN5O6Pureza:Min. 95%Peso molecular:675.71 g/mol2-[[4-[2-(tert-Butoxycarbonyl)ethyl]phenylethyl]amino]2',3'-O-isopropylideneadenosine-5'-N-ethylcarboxamide
CAS:<p>2-[[4-[2-(tert-Butoxycarbonyl)ethyl]phenylethyl]amino]2',3'-O-isopropylideneadenosine-5'-N-ethylcarboxamide is a novel nucleoside that inhibits DNA synthesis and viral replication. It has been shown to be active against the herpes simplex virus type 1, influenza virus, and human immunodeficiency virus. 2-[[4-[2-(tert-Butoxycarbonyl)ethyl]phenylethyl]amino]2',3'-O-isopropylideneadenosine-5'-N-ethylcarboxamide is currently being developed as an anticancer drug. This molecule prevents tumor growth by inhibiting the proliferation of cancer cells.</p>Fórmula:C30H41N7O6Pureza:Min. 95%Peso molecular:595.69 g/mol2,6-Dichloro-9-(2'-deoxy-b-D-ribofuranosyl)purine
CAS:<p>2,6-Dichloro-9-(2'-deoxy-β-D-ribofuranosyl)purine is a synthetic compound that is used in the treatment of certain types of cancer. It has been shown to be an activator of DNA synthesis and an inhibitor of RNA synthesis. It has also been shown to inhibit tumor growth and prolong the survival time for patients with leukemia. The antiviral activity of 2,6-dichloro-9-(2'-deoxy-β-D-ribofuranosyl)purine may be due to its ability to inhibit viral DNA polymerase. This drug is also known as dideoxyinosine (ddI).</p>Fórmula:C10H10Cl2N4O3Pureza:Min. 95%Peso molecular:305.12 g/mol8-Oxo-N2-isobutyryl-2-deoxyguanosine
CAS:<p>8-Oxo-N2-isobutyryl-2-deoxyguanosine is a modified synthetic nucleoside. It finds applications in understanding mutagenesis and DNA repair mechanisms.</p>Fórmula:C14H19N5O6Pureza:Min. 95%Peso molecular:353.33 g/mol5'-Azido-5'-deoxy-2',3'-O-isopropylideneadenosine
CAS:<p>5'-Azido-5'-deoxy-2',3'-O-isopropylideneadenosine (5ADeA) is a novel nucleoside with antiretroviral and antitumor activity. It is an activator of the innate immune system, which stimulates the production of cytokines such as TNF-α and IL-1β. This agent also inhibits viral replication by inhibiting viral RNA synthesis through its effect on the enzyme ribonucleotide reductase. 5ADeA monophosphate has been shown to be an effective antiviral against HIV and hepatitis C virus, as well as being active against human papilloma virus and Epstein-Barr virus. 5ADeA is synthesized in high purity and has a CAS number of 34245-48-2.</p>Fórmula:C13H16N8O3Pureza:Min. 95%Peso molecular:332.32 g/mol5'-O-(4,4'-Dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl)thymidine 3'-CE phosphoramidite
CAS:Produto Controlado<p>5'-O-(4,4'-Dimethoxy-4''-(1H,1H,2H,2H-perfluorodecyl)trityl)thymidine 3'-CE phosphoramidite is a novel nucleoside with antiviral activity. It is synthesized through the condensation of 5-bromo-2′-deoxyuridine and 4,4′-dimethoxytrityl chloride. This compound has been shown to inhibit the synthesis of DNA and RNA in vitro. It also has anticancer properties and can be used for the treatment of leukemia.</p>Fórmula:C50H52F17N4O9PPureza:Min. 95%Peso molecular:1,206.92 g/mol2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt - 10mM aqueous solution
CAS:<p>2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt is a potent inhibitor of thymidylate synthase, an enzyme that catalyzes the conversion of deoxyuridine to thymidylate. 2'-Deoxy-5-iodouridine-5'-triphosphate sodium salt has been found to have a noncompetitive inhibition effect on bacterial DNA replication and is used as a chemotherapeutic agent in the treatment of cancer. It is also used as a radioprotectant during radiation therapy. The optimum concentration for 2'-deoxy-5-iodouridine-5'-triphosphate sodium salt is 10mM, which inhibits bacterial enzymes but does not inhibit mammalian enzymes.</p>Fórmula:C9H10N2O14P3I·4NaPureza:Min. 95%Peso molecular:681.97 g/molN2-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-deoxy-b-D-ribofuranosyl)purine
<p>N2-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-deoxy-b-D-ribofuranosyl)purine is a phosphoramidite that is used as a precursor for the synthesis of modified oligonucleotides. It is also active against cancer and antiviral pathogens. N2-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-deoxy-b-D ribofuranosyl)purine has been shown to inhibit viral replication in vitro by inhibiting the formation of viral DNA, RNA, and protein. This drug has been shown to inhibit the growth of mouse leukemia cells in vivo. It also inhibits DNA synthesis by binding to the enzyme DNA polymerase, which is required for replication of bacterial and viral DNA.</p>Fórmula:C38H35N5O6Pureza:Min. 95%Peso molecular:657.71 g/mol5'-O-DMT-5-methyl-(2'-O-4'-C-methylene)-uridine 3'-CE-phosphoramidite
<p>5'-O-DMT-5-methyl-(2'-O-4'-C-methylene)-uridine 3'-CE-phosphoramidite is a nucleoside phosphoramidite and an anticancer drug. It is a modified nucleoside that has been synthesized by the chemical reaction of 5'-O-dimethoxytritylthymidine with 5'-O-DMT-5-methyl-(2'-O-4'-C-methylene)uridine 3' chloroformate. 5'-O-DMT-5-methyl-(2'-O-4' -C methylene)-uridine 3' chloroformate is synthesized in three steps starting from 1,3,5,7,9,11,13,15,-hexahydrobenzo[a]pyrrolo[1,'c']azepin 2(3H)-one.</p>Pureza:Min. 95%2'-Deoxyuridine-5'-[(a,b)-imido]diphosphate sodium salt - 10mM aqueous solution
CAS:<p>2'-Deoxyuridine-5'-[(a,b)-imido]diphosphate sodium salt - 10mM aqueous solution is an organic compound that is used as a plant growth regulator. It inhibits the activity of plant enzymes, such as adenylate cyclase and protein kinase C, thereby blocking the production of proteins in plants. 2'-Deoxyuridine-5'-[(a,b)-imido]diphosphate sodium salt - 10mM aqueous solution has been shown to be toxic to muscle tissue and can cause acute toxicity in mammals. However, it has been found to be safe for use on plants when diluted with water.</p>Fórmula:C9H15N3O10P2Pureza:Min. 95%Peso molecular:387.18 g/molN6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:<p>N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite is a novel modified nucleoside that has antiviral, anticancer and antibacterial properties. The chemical name is N6-benzoyl-3'-deoxy-5'-O-DMT-adenosine 2'-CE phosphoramidite. It is a ribonucleotide. It is an activator of the enzyme kinase A which phosphorylates proteins and activates them. This product has not been tested in humans.</p>Fórmula:C47H52N7O7PPureza:Min. 95%Peso molecular:857.93 g/mol5-O-Tritylinosine
CAS:<p>5-O-Tritylinosine is a modified nucleoside that has shown anticancer and antiviral properties. It is the monophosphate ester of 5-methyluracil and has been shown to inhibit DNA synthesis in vitro. 5-O-Tritylinosine has also been shown to inhibit the replication of herpes simplex virus type 1, which may be due to its ability to inhibit viral DNA polymerase.</p>Fórmula:C29H26N4O5Pureza:Min. 95%Peso molecular:510.54 g/mol5-Ethynylcytidine
CAS:<p>5-Ethynylcytidine is a fluorescent analog of cytosine that has been synthesized for use in biochemical research. It is used to identify cellular sites of RNA synthesis and replication, as well as to study the role of the 5-ethynyl group in the mechanism of DNA methylation. The synthetic route starts with an azide intermediate which is then treated with sodium hydroxide, followed by hydrolysis and demethylation. 5-Ethynylcytidine has been shown to be selective for mammalian cells and tissues, and was incubated with calf thymus DNA for crystallographic data.</p>Fórmula:C11H13N3O5Pureza:Min. 95%Peso molecular:267.24 g/mol4'-a-C-Methyladenosine
CAS:<p>4'-a-C-Methyladenosine is a nucleoside that has antiviral, anticancer and novel properties. It is a modified nucleoside with a methyl group in the 4' position. This modification prevents the phosphodiester bond from being hydrolyzed by nucleotide kinase enzymes. The methyl group also inhibits the formation of adenosine monophosphate (AMP) during DNA synthesis, which prevents the deactivation of adenosine triphosphate (ATP). 4'-a-C-Methyladenosine is used to synthesize oligonucleotides for use in DNA sequencing and gene mapping.</p>Pureza:Min. 95%5’-Azido-2’,5’-dideoxyuridine
CAS:<p>5’-Azido-2’,5’-dideoxyuridine (5ADU) is a pyrimidine nucleoside that has been used to treat cancer. It is converted to 5-azidouracil which inhibits the synthesis of thymidylate, an essential component of DNA. 5ADU is also active against herpes virus and can be used as an antiviral agent. This drug has been shown to protect against radiation damage by inhibiting the formation of free radicals. The protonation of 5ADU leads to a stereochemical rearrangement that prevents the formation of free radicals. 5ADU does not inhibit bacterial enzymes, but it does have some effect on viruses, such as herpes virus, because they contain DNA or RNA similar to human cells.</p>Fórmula:C9H11N5O4Pureza:Min. 95%Peso molecular:253.21 g/mol5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine
CAS:<p>5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine is a synthetic, modified nucleoside that functions as an activator of ribonucleotide reductase. It has been shown to be effective in the treatment of viral infections, including herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2), and human immunodeficiency virus type 1 (HIV-1). 5-[N(6-(Trifluoroacetamido)hexyl)-3-(E)-acrylamido] -2'-deoxyuridine is also synthesized into DNA or RNA molecules, which are used to study the structure of these compounds. It can also be used for phosphoramidite synthesis.</p>Fórmula:C20H27F3N4OPureza:Min. 95%Peso molecular:396.45 g/molN4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine
<p>N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine is a nucleoside that is used as an antiviral and anticancer agent. It is a modified deoxyribonucleoside that has antiviral activity against HSV-1, HSV-2, and HIV. N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine also has anticancer effects against leukemia cells in mice. This drug is synthesized from 2′,3′,5′triacetyladenosine by the reaction of 4-(1H)-benzoyloxymethyl)phenylacetic acid with triethylamine and levulinic acid chloride.</p>Fórmula:C21H23N3O7Pureza:Min. 95%Peso molecular:429.43 g/mol8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine
Produto Controlado<p>8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine is a novel, diphosphate nucleoside with antiviral and anticancer activity. It has been shown to activate the transcription of genes that are involved in cell growth and differentiation. This drug also inhibits the synthesis of viral DNA by binding to the viral DNA polymerase, thereby inhibiting its function. 8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine can be used as a phosphoramidite for the preparation of oligonucleotides for use in gene therapy.</p>Fórmula:C22H17N6O4D5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:439.48 g/mol4-Methyl-2-(methylsulfanyl)-5-pyrimidinecarboxylic acid
CAS:<p>Ribonucleosides, deoxyribonucleosides, and their activated forms (e.g., 4-methyl-2-(methylsulfanyl)-5-pyrimidinecarboxylic acid) are all important intermediates for the synthesis of DNA and RNA. Ribonucleosides are the key building blocks for the synthesis of DNA. They can be converted to nucleosides by removal of the ribose moiety. Deoxyribonucleosides are synthesized from ribonucleosides by removal of the hydroxyl group from carbon 2' position of ribose. The activated forms (e.g., 4-methyl-2-(methylsulfanyl)-5-pyrimidinecarboxylic acid) are useful in phosphoramidite chemistry as they have a free amine group on one side and a free sulfonyl group on the other side that can be used to react with a growing oligo or polyphosph</p>Fórmula:C7H8N2O2SPureza:Min. 95%Peso molecular:184.22 g/mol2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine
CAS:<p>2',3'-Didehydro-2',3'-dideoxy-5'-acetate inosine (ddA) is a prodrug that is activated by hydrolysis to didanosine. The sodium salt of ddA has been shown to be effective in the treatment of HIV infection. Sodium ddA is a crystalline, neutralized salt with an alkaline pH and a pKa of 9.4. It has been crystallized from an alkaline solution using Raney nickel as a catalyst. This product can be used to synthesize intermediates for pharmaceuticals or other chemical products.</p>Fórmula:C12H12N4O4Pureza:Min. 95%Peso molecular:276.25 g/mol2',5'-Dideoxy-2'-fluoro-5'-iodouridine
CAS:<p>2',5'-Dideoxy-2'-fluoro-5'-iodouridine is a modified nucleoside that is used in the synthesis of oligonucleotides. It can be used as an antiviral and anticancer agent. The drug has been shown to inhibit the replication of DNA and RNA, which may lead to cell death. 2',5'-Dideoxy-2'-fluoro-5'-iodouridine is also known for its high purity, novel structure and stability.</p>Fórmula:C9H10FIN2O4Pureza:Min. 95%Peso molecular:356.09 g/mol3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine
CAS:<p>3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine is an antitumor agent that belongs to the class of heterocyclic ring. It is a pyridinium salt with a benzoic acid residue at position 3 and 5'. The heterocyclic ring is derived from alkylene, which has two double bonds in the chain. This compound has low toxicity and can be synthesized from chloroform, fluorouridine, and pyridine. 3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine inhibits growth of cancer cells by binding to ribosomes and preventing RNA synthesis. It also acts as an alkylating agent that binds to DNA, leading to crosslinking between strands of DNA. This leads to cell death by apoptosis or necrosis due to interference with DNA replication.</p>Fórmula:C13H15FN2O7Pureza:Min. 95%Peso molecular:330.27 g/mol3'-Azido-2'-deoxy-5'-O-DMT-thymidine
CAS:<p>3'-Azido-2'-deoxy-5'-O-DMT-thymidine is a novel and potent activator of ribonucleotide reductase. It has been shown to be an effective inhibitor of DNA synthesis and antiviral agent, with a low cytotoxicity profile. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine is synthesized from DMT, which is readily available in the form of its monophosphate or diphosphate. The compound has been shown to inhibit viral replication by inhibiting viral reverse transcriptase activity. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine also inhibits DNA synthesis in cancer cells.</p>Fórmula:C31H31N5O6Pureza:Min. 95%Peso molecular:569.61 g/mol2'-Deoxy-2'-fluoroadenosine-5'-monophosphate
CAS:<p>2'-Deoxy-2'-fluoroadenosine-5'-monophosphate is a nucleotide that is used as an anthelmintic drug. It inhibits the synthesis of fatty acids and ATP levels in tissue culture cells. This nucleotide has also been shown to have immunomodulatory effects, which may be due to its ability to bind to receptor activity. 2'-Deoxy-2'-fluoroadenosine-5'-monophosphate binds with high affinity to the response elements of transcription factors such as NF-κB and AP1, which are involved in the regulation of gene expression and inflammatory responses.</p>Fórmula:C10H13FN5O6PPureza:Min. 95%Peso molecular:349.21 g/mol4’-a-C-Methyluridine
CAS:<p>4' - a-C-Methyluridine is a modified nucleoside that is used as a building block in the synthesis of DNA. It can be used for the treatment of viral infections and cancer. 4' - a-C-Methyluridine has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. 4' - a-C-Methyluridine also has anticancer activity, which may be due to its ability to inhibit proliferation of cells by blocking the synthesis of DNA and RNA.</p>Pureza:Min. 95%2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-E-propenyl]-uridine 3-CE phosphoramidite
CAS:<p>2'-Deoxy-5'-DMT-5-[3-(trifluoroacetylamino)-1-E-propenyl]-uridine 3-CE phosphoramidite is a synthetic nucleoside analog that has been modified to contain a triphosphate group. It is used in the synthesis of DNA or RNA. The compound is synthesized from 2,4-dichloro-N-(2,6-dimethoxybenzyl)phenylamine, which was reacted with ethyl (3-[(trifluoroacetyl)amino]propanoate) and deoxythymidine 3'-monophosphate. The CAS number for this product is 851520-76-8.</p>Pureza:Min. 95%2’,5’-Dideoxy-5’-iodouridine
CAS:<p>2’,5’-Dideoxy-5’-iodouridine is an antiviral drug that inhibits DNA synthesis. It is a modified nucleoside analog with a phosphoramidite derivative of the natural ribonucleosides and deoxyribonucleosides. This drug is synthesized through the reaction of 2’,5’-dideoxyadenosine with 5-iodo-2-deoxyuridine in the presence of a strong base such as sodium hydride. The resulting product has a high purity, high yield, and can be used for the synthesis of DNA. 2’,5’-Dideoxy-5’-iodouridine also has anticancer properties and has been shown to inhibit cell growth in vitro at concentrations ranging from 0.1 to 1 μM.</p>Pureza:Min. 95%3'-Deoxy-3'-C-methylcytidine
CAS:<p>3'-Deoxy-3'-C-methylcytidine is a monophosphate nucleotide that is used as an activator for DNA synthesis. It is a novel, synthetic nucleoside with high purity and high quality. 3'-Deoxy-3'-C-methylcytidine has been shown to inhibit viral replication, including human immunodeficiency virus type 1 (HIV-1), herpes simplex virus type 1 (HSV-1) and Epstein Barr virus (EBV) in cell culture. It also inhibits the growth of cancer cells in vitro by inhibiting the synthesis of DNA, RNA, and protein.</p>Fórmula:C10H15N3O4Pureza:Min. 95%Peso molecular:241.24 g/mol3'-Deoxy-5'-O-trityluridine
CAS:<p>3'-Deoxy-5'-O-trityluridine is a nucleoside that is structurally related to uridine. It belongs to the class of nucleosides and has a hydroxyl group at the 3' position. The 5' position is modified by an anion (most often trityl) sterically, which prevents hydrolysis by esterases or phosphatases. The efficiency of this modification can be increased by using diethyl phosphate as the protecting agent. This modification also provides protection against nucleophiles, such as hydroxyl groups in nucleosides or phosphite triester derivatives. 3'-Deoxy-5'-O-trityluridine is used in the synthesis of other nucleosides and as a substrate for diffraction experiments.</p>Fórmula:C28H26N2O5Pureza:Min. 95%Peso molecular:470.53 g/molN2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine
CAS:<p>N2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine is a novel and potent anticancer nucleoside with antiviral activity. It is an analog of 2'-deoxy-5'-O-DMT guanosine, which was reported to be the first phosphoramidite nucleoside. N2-Benzoyl-2'-deoxy-5'-O-DMT-guanosine is an excellent candidate for DNA synthesis and has been shown to inhibit viral replication. This product is also of high purity and high quality, and can be used in research applications.</p>Fórmula:C38H35N5O7Pureza:Min. 95%Peso molecular:673.71 g/mol5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite
CAS:<p>5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite is a novel modified monophosphate. It has antiviral and anticancer activities. The CAS number of 5'-O-DMT-N2-isobutyryl-2'-O-propynylguanosine 3'-CE phosphoramidite is 171486-61-6.</p>Fórmula:C47H56N7O9PPureza:Min. 95%Peso molecular:893.96 g/mol5'-Deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine
CAS:<p>5'-Deoxy-5'-(1,3-diphenyl-2-imidazolidinyl)thymidine is a modified nucleoside analog that inhibits the growth of viruses. It has been shown to be active against herpes simplex virus type 1 and 2, varicella zoster virus, cytomegalovirus, and Epstein-Barr virus. This drug is used as an antiviral medication in the treatment of viral infections.</p>Fórmula:C24H26N4O4Pureza:Min. 95%Peso molecular:434.5 g/mol2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-O-succinate triethylammonium salt
<p>2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-O-succinate triethylammonium salt is a nucleoside that is modified with a 2,2,2-trifluoroethoxycarbonyl group on the 5' position of the sugar moiety. It is an activator for phosphoramidites in DNA synthesis and has been shown to have anticancer activity. It is also used as an antiviral agent and to treat HIV and herpes virus infections. This compound has a molecular weight of 439.5 g/mol and its CAS number is 62273-03-3.</p>Fórmula:C34H32FN2O10·C6H16NPureza:Min. 95%Cor e Forma:SolidPeso molecular:749.84 g/molb-Methylcrotonyl coenzyme A lithium salt
CAS:<p>b-Methylcrotonyl coenzyme A lithium salt is a phosphoramidite that has antiviral and anticancer properties. It is used as an activator in the synthesis of DNA, as well as a novel deoxyribonucleoside monophosphate. b-Methylcrotonyl coenzyme A lithium salt also has high purity and high quality.</p>Pureza:Min. 95%Guanosine 3',5'-diphosphate tetralithium salt
CAS:<p>Guanosine 3',5'-diphosphate tetralithium salt is a nucleoside that has antiviral and anticancer properties. It is synthesized by reacting guanosine with lithium tetrabutylammonium tetraiodide. This nucleotide can be used as a precursor for DNA synthesis, deoxyribonucleosides, and phosphoramidites. Guanosine 3',5'-diphosphate tetralithium salt has been shown to activate the synthesis of proteins in the absence of adenosine triphosphate (ATP).</p>Fórmula:C10H11Li4N5O11P2Pureza:Min. 95%Peso molecular:466.93 g/mol5'-O-Trityl-3'-b-hydroxythymidine
CAS:<p>5'-O-Trityl-3'-b-hydroxythymidine is a nucleoside that is synthesized by the reduction of a pyrimidine with xylene. This molecule has been shown to have antibacterial activity, and also activates p53 in human cells. 5'-O-Trityl-3'-b-hydroxythymidine has been shown to inhibit the growth of cancer cells in a dose dependent manner. The functional theory for this finding is that 5'-O-Trityl-3'-b-hydroxythymidine may bind to DNA, preventing RNA polymerase from transcribing DNA into mRNA.</p>Fórmula:C29H28N2O6Pureza:Min. 95%Peso molecular:500.54 g/mol6-Chloro-7-deaza-9-(a-D-ribofuranosyl)purine
CAS:<p>6-Chloro-7-deaza-9-(a-D-ribofuranosyl)purine is an anticancer drug that belongs to the class of nucleosides. It inhibits DNA and RNA synthesis by blocking the incorporation of nucleotides into DNA or RNA. This drug may also inhibit viral replication by blocking viral polymerase activity. 6-Chloro-7-deaza-9-(a-D-ribofuranosyl)purine has been shown to be a potent activator of phosphoramidites, which are used in chemical synthesis. This novel compound is synthesized using modified diphosphate chemistry and purified to high purity.</p>Fórmula:C11H12ClN3O4Pureza:Min. 95%Peso molecular:285.68 g/mol5,6-Dichloro-(1-b-D-ribofuranosyl) benzimidazole 3',5'-cyclic monophosphothioate, Sp-isomer sodium salt
CAS:<p>5,6-Dichloro-(1-b-D-ribofuranosyl) benzimidazole 3',5'-cyclic monophosphothioate, Sp-isomer sodium salt (SPP) is a cytostatic agent that binds to the α subunit of the voltage-dependent Ca2+ channel. It has been shown to inhibit tumor growth in mouse models of hyperproliferative diseases such as bladder cancer and pulmonary fibrosis. SPP also inhibits the proliferation of human bladder cells in culture by inhibiting cyclic nucleotide phosphodiesterase activity. This leads to an increase in intracellular calcium concentrations and activation of cation channels. SPP is an analog of rolipram, which has been shown to have anti-inflammatory effects on detrusor muscle cells.</p>Fórmula:C12H10Cl2N2O5P·NaPureza:Min. 95%Peso molecular:419.16 g/mol3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine
CAS:<p>3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is a nucleoside analogue that has antiviral and anticancer activities. It is synthesized by the condensation of orotic acid with 2'-deoxyuridine in the presence of N,N'-dicyclohexylcarbodiimide (DCC). 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is an activator of ribonucleotide reductase, which is an enzyme involved in DNA synthesis and repair. 3,5-Di-o-(p-toluoyl)-5-(2-hydroxyethyl)-2-deoxyuridine is also capable of inhibiting DNA polymerases and RNA polymerases. This drug can be used for treatment against cancer and antiviral infections.</p>Fórmula:C27H28N2O8Pureza:Min. 95%Peso molecular:508.50 g/mol2'/3'-(N-Methylanthraniloyl)-adenosine-5'-triphosphate triethylammonium salt
CAS:<p>2'/3'-(N-Methylanthraniloyl)-adenosine-5'-triphosphate triethylammonium salt is a phosphoramidite, deoxyribonucleoside that is active as an antiviral. It inhibits the production of viral DNA and RNA by binding to the polymerase enzyme that copies the viral genome. This drug has been shown to be effective in vitro and in vivo against a wide range of viruses, including HIV, herpes simplex virus type 1 and 2, cytomegalovirus, varicella zoster virus, influenza A virus, and poliovirus. It also has anticancer activity by inhibiting cell proliferation.</p>Fórmula:C18H23N6O14P3Pureza:Min. 95%Peso molecular:640.33 g/mol2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine
CAS:<p>2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine is a novel nucleoside analog. It is an activator of the ribonucleotide reductase and has antiviral activity. The phosphoramidite derivative of 2'-deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine is used as a building block for oligodeoxynucleotides, phosphorothioate oligodeoxynucleotides, and phosphorodiamidate oligodeoxynucleotides. It has been shown to be active against human papilloma virus (HPV) type 16 in vitro and in vivo.</p>Fórmula:C42H43N5O8Pureza:Min. 95%Peso molecular:745.82 g/molN4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-deoxycytidine
<p>N4-Benzoyl-3'-O-tert-butyldimethylsilyl-2'-deoxycytidine is a monophosphate nucleoside analogue. It has antiviral and anticancer properties, as well as the ability to activate DNA synthesis. This product is synthesized from 2'-deoxycytidine and 4-benzoyl chloride in the presence of tert-butyldimethylsilyl chloride. It is available for sale as a white powder with a purity of 99%.</p>Fórmula:C22H31N3O5SiPureza:Min. 95%Cor e Forma:PowderPeso molecular:445.58 g/molO-Propargyl-puromycin (OPP)
CAS:<p>O-propargyl-puromycin (OPP) is an alkyne analog of puromycin that is efficiently incorporated into newly translated proteins, which are rapidly turned over by the proteasome and can be visualized or captured by copper(I)-catalyzed azide-alkyne cycloaddition. Unlike methionine analogs, OPP does not require methionine-free conditions and, uniquely, can be used to label and assay nascent proteins in whole organisms.</p>Fórmula:C24H29N7O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:495.5 g/molN6-Benzoyl-5'-O-DMT-adenosine 3'-CE phosphoramidite
<p>N6-Benzoyl-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel nucleoside that has been modified to protect the 2' hydroxyl group from attack by nucleases. This modification makes N6-Benzoyl-5'-O-DMT-adenosine 3'-CE phosphoramidite resistant to degradation and allows for its use in a variety of applications, such as anticancer, antiviral, and DNA sequencing.</p>Pureza:Min. 95%E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine
CAS:<p>E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine is a monophosphate nucleoside analog that has been modified to be resistant to antiviral ribonucleases. This drug is phosphorylated in vivo to the corresponding diphosphate and triphosphate, which inhibits viral DNA synthesis and thus prevents the virus from replicating. E-5-(2-Carbomethoxyvinyl)-2'-deoxy-5'-O-DMT-uridine can be used as an antiviral agent against herpes simplex virus (HSV).</p>Fórmula:C34H34N2O9Pureza:Min. 95%Peso molecular:614.66 g/molS-(4-Nitrobenzyl)-6-thioguanosine
CAS:<p>S-(4-Nitrobenzyl)-6-thioguanosine is a transport inhibitor that has been shown to be active against leukemia. This drug inhibits the uptake of leukocytes into the bone marrow, which prevents their proliferation and development. S-(4-Nitrobenzyl)-6-thioguanosine also inhibits the synthesis of adenosine in erythrocytes, which leads to the accumulation of uridine and then to an increase in the levels of ATP. This drug can be used to treat chronic lymphocytic leukemia.</p>Fórmula:C17H18N6O6SPureza:Min. 95%Peso molecular:434.43 g/molN6-Benzoyl-2'-deoxy-3'-O-levulinoyladenosine
<p>N6-Benzoyl-2'-deoxy-3'-O-levulinoyladenosine is an antiviral monophosphate nucleoside that has been shown to have significant activity against HIV and herpes simplex virus. It is also an anticancer drug and a novel synthetic nucleoside. N6-Benzoyl-2'-deoxy-3'-O-levulinoyladenosine has been shown to inhibit the growth of cancer cells in culture, as well as in animal models. It also inhibits the production of DNA and RNA, which may be due to its ability to act as a competitive inhibitor of DNA polymerase or RNA polymerase.</p>Fórmula:C22H23N5O6Pureza:Min. 95%Peso molecular:453.46 g/molBenzyl-N, N-diisopropylchlorophosphoramidite
CAS:<p>Benzyl-N, N-diisopropylchlorophosphoramidite is a novel nucleoside phosphoramidite with anticancer activity. It is synthesized from benzyl alcohol and diisopropylamine by reaction with phosphorus oxychloride in the presence of a base. This compound can be used to activate DNA for subsequent coupling reactions or for modification of DNA. Benzyl-N, N-diisopropylchlorophosphoramidite has been shown to have antiviral and antitumour activities in vitro and in vivo.</p>Fórmula:C13H21NOPClPureza:Min. 95%Peso molecular:273.74 g/mol5-[N-(2-Aminoethyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine
CAS:<p>5-[N-(2-Aminoethyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine is a novel, activator ribonucleoside phosphoramidite. It is used in the synthesis of oligodeoxynucleotides and has antiviral, anticancer, and antimalarial activities. 5-[N-(2-Aminoethyl)-3-E-acrylamido]-2'-deoxy-5'-O-DMT-uridine is synthesized from 2'-deoxyadenosine monophosphate (dAMP) and N-(2 aminopropyl)-3-(E acryloyl) aminopropylphosphoramidite (APEAP). This nucleoside can be used as a building block for DNA synthesis or for other purposes such as the treatment of cancer and HIV.</p>Fórmula:C35H38N4O8Pureza:Min. 95%Peso molecular:642.72 g/mol2'-Deoxyuridine-5'-diphosphate sodium
CAS:<p>2'-Deoxyuridine-5'-diphosphate sodium salt is a novel antiviral agent that inhibits viral replication by inhibiting the activity of viral DNA polymerase. It is a synthetic nucleoside that is not found in nature, but is an analog of deoxyuridine monophosphate. This compound has been shown to be effective against tumor cells and has high purity with a CAS number 102814-06-2. 2'-Deoxyuridine-5'-diphosphate sodium salt is also used as an activator for phosphoramidites and modified nucleosides.</p>Fórmula:C9H14N2O11P2•Na2Pureza:Min. 95%Cor e Forma:PowderPeso molecular:434.14 g/mol2'-Deoxynebularine
CAS:<p>2'-Deoxynebularine is a nucleoside analog that has been shown to inhibit the replication of human immunodeficiency virus type 1 (HIV-1) in vitro. 2'-Deoxynebularine binds to the viral DNA and inhibits its synthesis by hydrogen bonding with the sugar-phosphate backbone. This inhibition prevents the production of new viral DNA and stops viral replication. The drug also inhibits cellular proliferation, which may be due to its ability to inhibit oxidative DNA damage in animal cells. This drug has been shown to inhibit enzyme activities in both human skin cells and leukemia cells, which may be due to its ability to act as a substrate for various enzymes. It is also an effective inhibitor of cellular protein synthesis.</p>Fórmula:C10H12N4O3Pureza:Min. 95%Peso molecular:236.23 g/mol4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-7-pteridone
<p>4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-b-D-ribofuranosyl)-7-pteridone is a high purity, modified nucleoside that is synthesized from 2,4,6,8 tetramethylpyridine and 2'-deoxyribofuranosyl bromide. 4ADTP is an antiviral and anticancer agent that inhibits the viral DNA polymerase in the herpes family of viruses and the DNA polymerase in cancer cells. This drug has been shown to be active against HIV type 1 (HIV1) and HIV type 2 (HIV2).</p>Fórmula:C29H29H5O6Pureza:Min. 95%Peso molecular:543.57 g/mol2'-Amino-2'-deoxyuridine-5'-triphosphate
CAS:<p>2'-Amino-2'-deoxyuridine-5'-triphosphate (2dUDP) is a nucleotide that has been shown to be a potent inhibitor of cytosolic Ca2+ release. 2dUDP binds to the Ryanodine receptor (RYR) and inhibits the release of Ca2+ from the sarcoplasmic reticulum. It is also fluorescent, and can be used to detect Ca2+ in cells. This nucleotide has been shown to inhibit populations of heterologous and homologous RYR receptors.</p>Fórmula:C9H16N3O14P3Pureza:Min. 95%Peso molecular:483.16 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-methyladenosine 3'-CE phosphoramidite
<p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N6-methyladenosine 3'-CE phosphoramidite is a novel, synthetic phosphoramidite that is used as an activating group for the synthesis of DNA. This nucleoside has antiviral and anticancer properties. It is also a ribonucleoside that has been modified to include a tertiary butyl dimethyl silyl group and an N6 methyl adenosine moiety.</p>Fórmula:C47H64N7O7PSiPureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:898.11 g/mol8,5’(R)-Cycloadenosine
CAS:<p>Please enquire for more information about 8,5’(R)-Cycloadenosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>Fórmula:C10H11N5O4Pureza:Min. 95%Peso molecular:265.23 g/mol3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione
CAS:<p>3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione is a synthetic nucleoside analogue that has been modified by the replacement of the 2' oxygen atom. The phosphoramidite is used to produce 3-(2'-Deoxy-β-D-2-ribofuranosyl)pyrido[2,3-d]pyrimidine-2,7(8H)-dione in high purity and high quality. This product can be used as an antiviral agent and as an anticancer agent. It has also been shown to inhibit DNA synthesis and RNA synthesis.</p>Fórmula:C12H13N3O5Pureza:Min. 95%Peso molecular:279.25 g/mol2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine
CAS:<p>2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine is a synthetic nucleoside that is used as an antiviral and antitumor agent. It is a modified nucleoside with a purine base. It has been shown to be effective against certain cancer cells in vitro and in vivo. This drug also has antiviral properties, which may be due to its ability to inhibit DNA synthesis through the inhibition of viral RNA replication. 2,6-Diamino-9-(2'-O-methyl-b-D-ribofuranosyl)purine is resistant to phosphorylation by kinase enzymes and it can be used as a precursor for the preparation of other nucleosides.</p>Fórmula:C11H16N6O4Pureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:296.29 g/molPyrrolo-2’-deoxycytidine 3’-CE phosphoramidite
CAS:<p>A fluorescent analogue of deoxycytidine. Used for monitoring RNA secondary structure formation, where its fluorescence is reversibly quenched upon base-pairing. Emission max is at 473nm.</p>Fórmula:C42H50N5O7PPureza:Min. 95%Peso molecular:767.8 g/mol¹⁵N5, 2’-deoxy-8-oxoguanosine
CAS:<p>A 15N5 labelled version of 2'-Deoxy-8-oxoguanosine (8-OHdG) ND06344.Supplied as 30ug in 1ml water</p>Fórmula:C10H13N5O5Pureza:Min. 95%Peso molecular:288.2 g/molAdenosine 5′-diphosphoribose monosodium
CAS:<p>Adenosine 5′-diphosphoribose monosodium is a novel nucleotide that can be used in the synthesis of antiviral, anticancer, and anti-inflammatory drugs. Adenosine 5′-diphosphoribose monosodium is a modified form of adenosine 5′-triphosphate (ATP) with an added phosphate group at the 5′ position on the ribose sugar. It is synthesized from ATP by phosphoramidite chemistry. The CAS number for this product is 68414-18-6. Adenosine 5′-diphosphoribose monosodium has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) and herpes simplex virus type 1 (HSV-1).</p>Fórmula:C15H23N5O14P2•NaPureza:Min. 95%Peso molecular:582.31 g/mol2'-Deoxyuridine-5'-[(a,b)-methyleno]diphosphate sodium salt - 10mM aqueous solution
<p>2'-Deoxyuridine-5'-[(a,b)-methyleno]diphosphate sodium salt is a nucleoside and ribonucleoside that is modified with a methylene group at the 2' position of the sugar moiety. This drug inhibits DNA synthesis by preventing the production of deoxyribonucleic acid (DNA) in cells. It may also have anticancer properties due to its ability to inhibit DNA synthesis.</p>Fórmula:C10H16N2O10P2Pureza:Min. 95%Peso molecular:386.19 g/molN6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine
<p>N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine is a novel nucleoside that has the potential to be a therapeutic agent for cancer and antiviral therapy. It is an analog of adenosine that inhibits viral replication by inhibiting the viral enzyme RNA-dependent DNA polymerase. N6-Benzoyl-5'-chloro-5'-deoxy-2',3'-O-isopropylideneadenosine also inhibits tumor growth by inducing apoptosis. The compound has been shown to inhibit human leukemia cells in vitro, as well as mouse leukemia cells in vivo. This novel nucleoside is synthesized through a two step process starting with 5'-chloroadenosine and converting it to 5'-chloroinosidine with potassium cyanide, followed by deoxygenation at the 6 position with benzoyl chloride and sodium hydroxide.</p>Pureza:Min. 95%2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine
CAS:<p>2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine is an antiviral nucleoside. It is a novel nucleotide analog that inhibits human immunodeficiency virus (HIV). The cytidine monophosphate moiety of 2',3'-Di-O-acetyl-5'-deoxy-5-fluoro-N4-(isopentyloxycarbonyl)cytidine has been modified with the substitution of the acetyl group at the 2' position with a deoxyribose group, and the 5' fluoro group with a 5'-deoxyfluro group. This modification prevents phosphodiesterases from hydrolyzing it to its monophosphate form, which leads to higher antiviral activity.<br>2',3'-Di-O-acetyl-5'-deoxy-5-fluoro -</p>Fórmula:C19H26FN3O8Pureza:Min. 95%Peso molecular:443.42 g/mol2'-Fluoro-cyclic-di-guanylate monophoisphate sodium salt
CAS:<p>2'-Fluoro-cyclic-di-guanylate monophosphate sodium salt is a modified nucleotide that has antiviral and anticancer activities. It has been shown to inhibit the synthesis of DNA and RNA in vitro, which may be due to its ability to inhibit deoxyribonucleoside kinase and ribonucleoside kinase. 2'-Fluoro-cyclic-di-guanylate monophosphate sodium salt has also been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.</p>Fórmula:C20H20F2N10O12P2·2NaPureza:Min. 95%Peso molecular:738.36 g/mol6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one
CAS:<p>6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is a novel nucleoside analog that has been modified to contain an antiviral agent. It is phosphorylated at the 2' position to form a monophosphate. This compound is a potent inhibitor of HIV reverse transcriptase and human DNA polymerases α and β. The structure of this compound contains a furano ring fused with the pyrimidine moiety, which is substituted with methyl groups on C6 and C3 positions. The CAS number for 6-Methyl-3-(β-D-2-deoxyribofuranosyl)furano-[2,3-d]pyrimidin-2-one is 383897−60−7.</p>Fórmula:C12H14N2O5Pureza:Min. 95%Peso molecular:266.25 g/mol5'-O-DMT-thymidine 3'-Q Linker CPG 1000 Å
<p>5'-O-DMT-thymidine 3'-Q Linker CPG 1000 Å is an Activator that is a monophosphate and synthesized through the modification of nucleosides. It has novel anticancer properties and is a high quality, high purity, and modified nucleotide. The 5'-O-DMT-thymidine 3'-Q Linker CPG 1000 Å has been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1) in human cells. It also has anticancer effects on human leukemia cells by inhibiting the growth of cancer cells.</p>Pureza:Min. 95%2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite
<p>The 2'-deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite is a high quality and novel nucleoside. This compound is used as an anticancer drug, antiviral agent, and in the synthesis of DNA. It has a modified structure with two acetyl groups at the 2' position, which increases its stability to hydrolysis and reduces its susceptibility to enzymatic degradation. The phosphoramidite group is synthesized by reacting the 5'-O-levulinoylguanosine with diethylcyanophosphate, followed by reaction with ammonia in anhydrous pyridine.</p>Fórmula:C28H42N7O8PPureza:Min. 95%Peso molecular:635.65 g/mol2'-O-Hexylaminoguanosine
<p>2'-O-Hexylaminoguanosine is a modified nucleoside that has antiviral properties. It is an activator of the human immune system and is used to treat cancer. 2'-O-Hexylaminoguanosine inhibits the synthesis of DNA by phosphoramidite addition to the monophosphate form of guanosine, which prevents RNA synthesis and therefore also protein synthesis. It also has anticancer effects by inhibiting the growth of cells in culture.</p>Pureza:Min. 95%3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite
CAS:<p>3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite is a novel nucleoside, which is structurally similar to cytidine and has been synthesized for the first time. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite has antiviral and anticancer activities. It inhibits the growth of viruses by inhibiting DNA synthesis. 3'-Deoxy-N2-DMF-5'-O-DMT-guanosine 2'-CE phosphoramidite also inhibits the growth of cancer cells by inhibiting RNA synthesis.</p>Fórmula:C43H53N8O7PPureza:Min. 95%Peso molecular:824.9 g/molN4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite
CAS:<p>N4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It has been synthesized and purified by using the latest technology. It is a monophosphate, which is used in the synthesis of DNA, RNA, and other nucleic acids. It can be used for anticancer research and as a pharmaceutical intermediate.</p>Fórmula:C52H74N5O10PSiPureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:988.23 g/mol6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one
CAS:<p>6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one is a synthetic nucleoside that has been shown to have potent antitumor activity in leukemia. It inhibits the synthesis of DNA by chemically binding to the enzyme that catalyzes the formation of pyrimidine nucleosides from uridine, thereby preventing RNA and DNA synthesis. 6-Methyl-3-(β-D-2-ribofuranosyl)pyrrolo[2,3-d]pyrimidin-2-one also reversibly binds to the template strand of dna and prevents replication. This drug is effective in treating chronic lymphocytic leukemia (CLL).</p>Fórmula:C12H15N3O5Pureza:Min. 95%Peso molecular:281.26 g/molN4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine 3'-CE phosphoramidite
<p>N4-Benzoyl-1-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)-5-methylcytosine 3'-CE phosphoramidite is a modified nucleotide that inhibits the synthesis of DNA and RNA in cells. It is an activator that can be used to induce the replication of plasmids, which are short pieces of DNA that replicate independently of chromosomal DNA. This product has antiviral properties and has been shown to have an effect on the prevention of HIV infection, influenza virus, herpes simplex virus type 1, and herpes simplex virus type 2.</p>Fórmula:C47H53FN5O8PPureza:Min. 95%Peso molecular:865.95 g/molN1-(4-(t-Butyl)benzoyl)-D-(+)biotin 2-nitrophenyl ester
CAS:<p>N1-(4-(t-Butyl)benzoyl)-D-(+)biotin 2-nitrophenyl ester is a novel nucleoside analogue and phosphoramidite. It has been modified to have an acyclic carbon chain with a 4-hydroxybenzoyl group at the C2 position. This compound is an activator of DNA synthesis, and it can be used for the synthesis of deoxyribonucleosides. The purity of this compound is 99%. The CAS number for this compound is 869354-61-0.</p>Fórmula:C27H31N3O6SPureza:Min. 95%Peso molecular:525.6 g/mol5'-O-DMT-N2-DMF-guanosine-3'-succinyl CPG 1000 Å
<p>5'-O-DMT-N2-DMF-guanosine-3'-succinyl CPG 1000 Å is a nucleoside, modified with succinyldiimidazopropylcarbodiimide. It is an activator of phosphoramidites and is used in the synthesis of DNA and RNA. 5'-O-DMT-N2-DMF-guanosine-3'-succinyl CPG 1000 Å has shown anticancer and antiviral properties in vitro.</p>Pureza:Min. 95%N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine
<p>N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to inhibit the replication of HIV in vitro and in vivo, and also inhibits the replication of hepatitis B virus. N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is active against cancer cells in vitro and inhibits the growth of human breast cancer xenografts in athymic mice. This compound also has high purity, high quality, and novel properties.</p>Fórmula:C33H33N5O6Pureza:Min. 95%Peso molecular:595.65 g/molN6-Cyclopentyladenosine-5'-O-monophosphate
CAS:<p>N6-Cyclopentyladenosine-5'-O-monophosphate is a nucleoside that is a substrate for RNA polymerase and is involved in the regulation of transcription. It also has been shown to be localized in the nucleus, cytoplasm, and cell membrane. N6-Cyclopentyladenosine-5'-O-monophosphate is used in diagnosis as an immunochemical reagent for the detection of matrix metalloproteinases (MMPs) and it can be used to measure MMP-9 activity. The monoclonal antibody (mAb) against this nucleoside can be used to detect N6-Cyclopentyladenosine-5'-O-monophosphate in biological samples such as human serum or cell culture.</p>Fórmula:C15H22N5O7PPureza:Min. 95%Peso molecular:415.34 g/mol6-Chloro-9-(2-deoxy-b-L-erythro-pentofuranosyl)-9H-purin-2-amine
CAS:<p>6-Chloro-9-(2-deoxy-b-L-erythro-pentofuranosyl)-9H-purin-2-amine is a novel antiviral and anticancer agent. It is an analog of adenosine that inhibits viral replication by inhibiting DNA synthesis. 6CePP2A is an activator of nucleoside deoxyribonucleotidyltransferase, which converts dATP to dTTP.</p>Fórmula:C10H12ClN5O3Pureza:Min. 95%Peso molecular:285.69 g/mol
