Nucleosídeos
Foram encontrados 3569 produtos de "Nucleosídeos"
2-Methoxycarbonyl adenosine
CAS:2-Methoxycarbonyl adenosine is a modified nucleoside and nucleotide. It is an antiviral agent that has been shown to be effective against herpes simplex virus type 1 (HSV-1) and varicella zoster virus (VZV). 2-Methoxycarbonyl adenosine also has anticancer activity, which may be due to its ability to inhibit DNA synthesis. This agent can also be used as a phosphoramidite for the synthesis of oligonucleotides and as a monophosphate for the synthesis of ribonucleosides. 2-Methoxycarbonyl adenosine is also available in high purity and high quality with CAS No. 70255-70-8.Pureza:Min. 95%2,8-Dimethyladenosine
CAS:2,8-Dimethyladenosine is a methylated derivative of the purine nucleoside adenosine, in which methyl groups are added at the 2-position and 8-position of the adenine base.Fórmula:C12H17N5O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:295.29 g/mol2'-Deoxy-5-methylcytidine
CAS:2'-Deoxy-5-methylcytidine is a nucleoside analogue that inhibits the synthesis of DNA. It prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine has been shown to inhibit colon cancer cells in vitro, and may be a potential biomarker for bowel disease. This drug is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules.
Fórmula:C10H15N3O4Pureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:241.25 g/molThymidine-3',5'-diphosphate sodium salt
CAS:Thymidine-3',5'-diphosphate sodium salt is a nucleoside that is used in the synthesis of oligonucleotides. It is an antiviral and anticancer agent. Thymidine-3',5'-diphosphate sodium salt has been shown to inhibit DNA synthesis, leading to cell death. It also has been shown to be effective against Hepatitis B virus and HIV-1.
Fórmula:C10H16N2O11P2·xNaPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:402.19 g/mol3'-Deoxythymidine
CAS:3'-Deoxythymidine (3DT) is a nucleoside analog that has high resistance to HIV. It is an analogue of the human insulin-like growth factor-1 (IGF-1), which binds to the IGF-1 receptor and inhibits the binding of IGF-1 to its receptor, thereby inhibiting the growth of cells. 3DT has been shown to have a protective effect against radiation in mice, with an LD50 at a dose of 5.0 mg/kg for radiation exposure. 3DT also has antiviral activity against murine sarcoma virus, as well as other biological properties such as enzyme activities and disease activity. This drug may be used in future research on polymerase chain reactions (PCRs) and DNA sequencing, since it is chemically stable and can be easily synthesized.Fórmula:C10H14N2O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:226.23 g/molN4-Benzoyl-2'-deoxy-a-cytidine
CAS:N4-Benzoyl-2'-deoxy-a-cytidine is a novel, modified nucleoside that has shown anticancer and antiviral activity. It is synthesized by the enzymatic oxidation of 2'-deoxyadenosine with benzoyl chloride and sodium bicarbonate. N4-Benzoyl-2'-deoxy-a-cytidine has been shown to activate transcription, increase DNA synthesis, and inhibit virus replication. It also inhibits bacterial growth, but does not appear to have any effect on mammalian cells.Fórmula:C16H17N3O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:331.32 g/mol2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine
CAS:2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.Pureza:Min. 95%N6-Benzoyl-5'-O-benzyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite
N6-Benzoyl-5'-O-benzyl-2'-O-tert-butyldimethylsilyladenosine 3'-CE phosphoramidite is an activator of ribonucleosides and deoxyribonucleosides. It is a novel synthetic nucleoside, which has high quality and purity. The chemical modification of the base allows for the synthesis of DNA with modified bases. This product has been shown to have anticancer effects in vitro and in vivo, as well as antiviral activities against HIV.Fórmula:C39H54N7O6PSiPureza:Min. 95%Peso molecular:775.97 g/molO2-3'-anhydro-β-D-fructofuranosyluracil
O2-3'-anhydro-beta-D-fructofuranosyluracil is a novel nucleoside analogue that has antiviral and anticancer properties. It is synthesized by the reaction of beta-D-fructofuranosyluracil with phosphoramidites. The product is purified by HPLC and characterized by IR spectroscopy, UV spectroscopy, and mass spectrometry.Pureza:Min. 95%2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt
CAS:2’-O-Methyl-5-methyluridine 5’-triphosphate triethylammonium salt is a nucleoside that can be used as an antiviral or anticancer drug. It is a modified nucleoside, which is synthesized by phosphoramidite chemistry. 2'-O-Methyl-5'-methyluridine 5'-triphosphate triethylammonium salt has been shown to be an activator of DNA polymerase in vitro and in vivo. It also has high purity and high quality.
Fórmula:C11H19N2O15P3Pureza:Min. 95%Peso molecular:512.19 g/molRibavirin 5'-triphosphate tetrasodium salt - 10mM aqueous solution
CAS:Ribavirin triphosphate is the biologically active metabolite of antiviral nucleoside analog ribavirin. In cells, the prodrug ribavirin gets triphosphorylated and in it inhibits viral RNA polymerases, interfering with the synthesis of newly formed RNA.Fórmula:C8H15N4O14P3·Na4Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:576.1 g/mol5-Methylcytidine
CAS:5-Methylcytidine is a nucleoside that is found in DNA and RNA. It is used in structural biology to probe the structure of DNA. 5-Methylcytidine binds to the enzyme methyl transferase, which catalyzes the transfer of a methyl group from S-adenosylmethionine to produce 5-methyluridine. This reaction occurs in long-term toxicity studies using primary cells, such as lymphocytes and fibroblasts. 5-Methylcytidine has been shown to inhibit tumour growth in mice by binding to nuclear dna polymerase and blocking transcription. The binding site for this drug on the polymerase is located at the same site as that for nucleoside analogues like azidothymidine (AZT) and zidovudine (AZT).
Fórmula:C10H15N3O5Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:257.24 g/molN4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite
N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is a novel monophosphate nucleotide that can be used for the synthesis of DNA and RNA. It has antiviral, anticancer, and activating properties. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-5-methylcytidine 3'-CE phosphoramidite is synthesized by modifying cytosine with an acetyl group at the 4th position in the ribose ring, a tertiary butyldimethylsilyl group at the 2nd position on the 5' carbon atom, and a DMT group at the 5' position on the 5' carbon atom. The CAS number for this compound is 868312050.Pureza:Min. 95%2’-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine
CAS:2’-O-Acetyl-3,5-bis-O-(2,4-dichlorobenzyl)adenosine (OAAD) is a novel nucleoside that has been modified to be phosphorylated by the enzyme ribonucleotide kinase. It is an antiviral and anticancer agent that affects the synthesis of DNA. OAAD inhibits viral replication in vitro and in vivo by inhibiting DNA synthesis.Fórmula:C26H23Cl4N5O5Pureza:Min. 95%Peso molecular:627.3 g/mol7-Deaza-2'-deoxy-7-iodoadenosine
CAS:7-Deaza-2'-deoxy-7-iodoadenosine (7DADI) is a modified nucleoside that has antiviral and anticancer properties. It is synthesized by the reaction of 2'-deoxyadenosine with iodine in the presence of an activator such as sodium hypochlorite. 7DADI binds to ribonucleosides, forming a phosphoramidate bond at the 3' position, which leads to inhibition of viral RNA synthesis and DNA replication. This drug also inhibits the growth of cancer cells by inhibiting DNA synthesis and protein synthesis. 7DADI is novel because it is not found in nature or produced by any other organism.
Fórmula:C11H13IN4O3Pureza:Min. 98 Area-%Peso molecular:376.16 g/mol2’-Deoxyisoguanosine
CAS:Incorporated in DNA/RNA hybrids and mismatch pairs to analyse helix stabilityFórmula:C10H13N5O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:267.24 g/mol5-Methylcytidine-5'-monophosphate
CAS:5-Methylcytidine-5'-monophosphate is a nucleotide that is an intermediate in the synthesis of DNA. It is a neutral form and has been sequenced. 5-Methylcytidine-5'-monophosphate is found in cellular components, such as mitochondria and nuclei. The biochemical properties of this molecule are dependent on its methylation state. This molecule also plays a role in mitochondrial functions and nuclear DNA modifications.
Fórmula:C10H16N3O8PPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:337.22 g/molN6-Benzyl-2-deoxyadenosine
N6-Benzyl-2-deoxyadenosine is a modified nucleotide that can be incorporated into DNA during replication. The compound has antiviral properties and can act as an activator for the transcription of genes involved in the immune response. It is synthesized by coupling two phosphate groups to adenosine monophosphate, which is then modified with a benzyl group. This modification prevents N6-benzyl-2-deoxyadenosine from being phosphorylated and degraded to adenosine monophosphate, resulting in a stable molecule that can be incorporated into DNA.Fórmula:C17H19N5O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:341.36 g/mol1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil
CAS:1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil is a novel, anticancer drug. It is active against both RNA and DNA viruses, such as HIV, influenza virus and herpes virus. 1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil has been shown to be an activator for phosphoramidites in aqueous solution. This compound is of high purity with CAS No. 2072145–25–4. It is also a synthesized, monophosphate nucleoside that can be used in the production of modified nucleosides for therapeutic purposes or as antiviral agentsPureza:Min. 95%
![1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FND162854.webp&w=3840&q=75)