Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one
CAS:3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a phosphoramidite that can be used for the synthesis of DNA. It has antiviral activity and has been shown to inhibit the growth of cancer cells. 3-beta-D-Ribofuranosyl-1H-pyrimido[5,4-b][1,4]benzoxazin-2(3H)-one is a novel nucleoside that is modified with a fluoroquinolone moiety. This modification inhibits viral replication by interfering with viral DNA polymerase. The novel nucleoside has also been shown to have anticancer activity in vitro and in vivo.Fórmula:C15H15N3O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:333 g/mol5'-Ethylcarboxamidoadenosine
CAS:5'-Ethylcarboxamidoadenosine (5-ECA) is an adenosine receptor antagonist that is used as a radioligand to study the binding of adenosine and other nucleotides to their receptors. 5-ECA binds to the A3 receptor, which is a member of the G protein-coupled receptor family. This compound also inhibits platelet aggregation and has been shown to have anti-inflammatory effects in mice with colon cancer. 5-ECA was found to inhibit tumor growth in a mouse model system by suppressing IL-2 production and reducing levels of PGE2, an effect that may be due to inhibition of cyclase activity. 5-ECA can be used in vitro for studies on pluripotent cells because it does not affect their ability to differentiate.Fórmula:C12H16N6O4Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:308.29 g/molN4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite is a monophosphate nucleoside analog that is synthesized in an acetylated form. It is an activator of DNA synthesis, and as such, has anticancer activity. This compound also inhibits the replication of DNA viruses and has antiviral activity against influenza virus. N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine 3'-CE phosphoramidite has been shown to be effective in the prevention of HIV infection in vitro.Fórmula:C41H49FN5O8PPureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:789.83 g/mol5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite
5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite is a monophosphate, which is a phosphate group that is attached to the 5' carbon on the ribose ring of RNA. This monophosphate has been modified with a 2'-O-methyl group at the 6 position of the adenosine moiety. It has also been modified with a phenoxyacetyl group at the 2 position of the adenosine moiety. The phosphoramidite backbone is an ester bond between phosphorus and nitrogen atoms, and it can be used to make DNA or RNA in vitro. This compound has anticancer properties and antiviral activities against HIV, HSV, and HBV. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine 3'-CE phosphoramidite has novel properties that have notFórmula:C49H56N7O9PPureza:Min. 95%Cor e Forma:White PowderPeso molecular:918.01 g/mol5’-Deoxy-5’-iodo-2’-O-methyluridine
CAS:5’-Deoxy-5’-iodo-2’-O-methyluridine is a nucleoside that is modified with the substitution of an iodine atom for a hydrogen atom on the 5′ carbon. It has antiviral and anticancer properties. The high purity and novel structure make this compound useful in DNA synthesis. This product can also be used as a phosphoramidite or deoxyribonucleoside building block in DNA synthesis.
Pureza:Min. 95%3'-Amino-3'-deoxyadenosine
CAS:3'-Amino-3'-deoxyadenosine, also known as spalgomycin, is a natural enediyne antibiotic with potent antibacterial and, more notably, antitumor activity observed in research settings. Its primary use is as a tool to study the mechanisms of enediyne-mediated DNA damage and as a lead compound in the search for novel anticancer therapeutics.Fórmula:C10H14N6O3Cor e Forma:White Off-White PowderPeso molecular:266.26 g/mol5'-O-DMT-uridine 3'-CE phosphoramidite
CAS:5'-O-DMT-uridine 3'-CE phosphoramidite is a novel, modified and activator nucleoside. It can be used as an antiviral agent or in the synthesis of DNA. 5'-O-DMT-uridine 3'-CE phosphoramidite has been shown to be cytotoxic in vitro to cancer cells.Fórmula:C39H47N4O9PPureza:Min. 95%Peso molecular:746.79 g/mol1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine
1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-docosanoyl)-cytosine is a deoxyribonucleoside monophosphate with antiviral effects. It is a novel nucleotide analogue that contains an azido group and a 2,4,6-trifluorobenzene moiety. The 4′ position of the sugar is modified with an n-docosanoyl group. 1-(4’Azo-2′deoxy-2′fluoro-bDara)ribonucleosides are synthetic nucleotides that can be used to inhibit viral replication by inhibiting DNA polymerase and RNA polymerase.Pureza:Min. 95%5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite
CAS:5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is a modified, phosphoramidite nucleoside. It is used in the synthesis of DNA and RNA. 5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is an antiviral agent that inhibits viral replication by inhibiting viral protein synthesis. It has been shown to be active against HIV, Hepatitis B virus, and Hepatitis C virus. The compound also has anticancer properties and has been shown to inhibit tumor growth in animal models. 5'-O-DMT-2'-O-methyluridine 3'-CE phosphoramidite is a novel synthetic nucleoside that can be used as an alternative to deoxyribonucleosides in the synthesis of DNA and RNA.Fórmula:C40H49N4O9PPureza:Min. 98 Area-%Cor e Forma:White PowderPeso molecular:760.83 g/mol2'-O-cyanoethyoxymethyl-5'-O-DMT-adenosine
2'-O-cyanoethyoxymethyl-5'-O-DMT-adenosine is a novel nucleoside analog that belongs to the group of cytidine analogs. It has antiviral activity, which is due to its ability to inhibit viral replication by disrupting the synthesis of viral RNA. This drug is an activator and can be used for cancer treatment. 2'-O-cyanoethyoxymethyl-5'-O-DMT-adenosine binds to ribonucleosides and deoxyribonucleosides, preventing their incorporation into DNA or RNA. It also inhibits the biosynthesis of RNA and DNA, which leads to cell death in tumor cells.Pureza:Min. 95%5-Methylcytidine-5'-monophosphate
CAS:5-Methylcytidine-5'-monophosphate is a nucleotide that is an intermediate in the synthesis of DNA. It is a neutral form and has been sequenced. 5-Methylcytidine-5'-monophosphate is found in cellular components, such as mitochondria and nuclei. The biochemical properties of this molecule are dependent on its methylation state. This molecule also plays a role in mitochondrial functions and nuclear DNA modifications.
Fórmula:C10H16N3O8PPureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:337.22 g/mol1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil
CAS:1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil is a novel, anticancer drug. It is active against both RNA and DNA viruses, such as HIV, influenza virus and herpes virus. 1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil has been shown to be an activator for phosphoramidites in aqueous solution. This compound is of high purity with CAS No. 2072145–25–4. It is also a synthesized, monophosphate nucleoside that can be used in the production of modified nucleosides for therapeutic purposes or as antiviral agentsPureza:Min. 95%5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite
5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite is a nucleoside monophosphate, which is used as a synthetic building block in DNA and RNA synthesis. 5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite has shown anticancer activity, which may be due to its ability to inhibit the activation of oncogenes by acting as an antagonist at the cell surface. This agent also inhibits viral replication and is active against HIV, herpes simplex virus type 1, and varicella zoster virus.Fórmula:C31H47N4O8PSiPureza:Min. 95%Peso molecular:662.8 g/mol2'-O-(2-Methoxyethyl)guanosine
CAS:2'-O-(2-Methoxyethyl)guanosine is a guanosine derivative isolated from the reaction of 2-aminoadenosine with methylsulfonyl chloride. This compound has been shown to react with aromatic hydrocarbons to form a reagent that is useful for the alkylation of nucleophilic groups in organic synthesis.Fórmula:C13H19N5O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:341.32 g/mol2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt
2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt is a nucleoside that can be used in the synthesis of DNA and RNA. It is a synthetic, high quality, and novel compound that has been shown to have antiviral, anticancer, and anti-inflammatory properties. This compound has been shown to inhibit the growth of cancer cells by inhibiting the production of proteins vital for cell division. 2-Chloro-2'-deoxyadenosine 5'-triphosphate sodium salt has also been shown to be an activator of nucleoside phosphorylase and deoxynucleotide kinase, which are enzymes that catalyze the conversion of nucleosides into their corresponding monophosphates.Pureza:Min. 95%8-Azidoadenosine
CAS:8-Azidoadenosine is an adenosine analogue conjugated with an azido group which can be used for oligonucleotide labelling. The azido group reacts with a terminal alkyne via a click reaction, forming the labelled nucleotide containing a triazole linker.
Fórmula:C10H12N8O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:308.25 g/mol2-Azidoadenosine
CAS:2-Azidoadenosine is a nucleoside analog of adenosine, where the 2'-hydroxyl group of the ribose sugar is replaced with an azido group (–N₃). This substitution imparts unique chemical properties, notably enabling molecules to undergo bioorthogonal reactions, such as click chemistry, which involves the cycloaddition of the azide group with alkynes.
Fórmula:C10H12H8O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:308.25 g/mol5-Iodo-2’-C-methylcytidine
CAS:5-Iodo-2’-C-methylcytidine is a synthetic nucleoside that is an activator of DNA polymerases. It has been shown to be an anticancer agent and antiviral agent, with potential applications in the treatment of HIV and HBV infections. 5-Iodo-2’-C-methylcytidine is a novel monophosphate nucleoside that has been modified to improve its stability. This product is sold as a high purity, high quality, NMR grade material that can be used in research or in the manufacture of pharmaceuticals.Fórmula:C10H14IN3O5Pureza:Min. 95%Peso molecular:383.14 g/mol2'-O-tert-Butyldimethylsilyl-N2-Isobutyryl-5'-O-tritylguanosine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-N2-Isobutyryl-5'-O-tritylguanosine 3'-CE phosphoramidite is an anticancer nucleoside, which is used as a building block to synthesize DNA and RNA. The compound has been shown to be effective against HIV and herpes simplex virus. It also has antiviral effects against influenza A virus, cytomegalovirus, and Epstein Barr virus.
Fórmula:C48H64N7O7PSiPureza:Min. 95%Peso molecular:910.15 g/mol5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine
CAS:5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine is a monophosphate antiviral agent. It has been shown to inhibit the activity of DNA and RNA polymerases in vitro. The drug is novel, and its antiviral properties have not been tested in vivo. 5’-O-DMT-3’-O-levulinyl-2’-deoxyadenosine has been synthesized using phosphoramidites and was found to be of high quality and purity. It has also been modified at the 2' position with an acetyl group and at the 3' position with a levulinoyl group.Pureza:Min. 95%
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