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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3567 produtos de "Nucleosídeos"

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  • 4’,5’-Didehydro-2’,5’-dideoxyuridine

    CAS:
    <p>4’,5’-Didehydro-2’,5’-dideoxyuridine (ddU) is a monophosphate of deoxyribonucleosides. It is an antiviral drug that was originally synthesized in the 1960s to combat viral infections. It has been used as a potential anticancer agent and as an activator for complex DNA synthesis. ddU has also been used in synthesis of phosphoramidites for DNA and RNA analogues.</p>
    Pureza:Min. 95%

    Ref: 3D-ND163033

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  • 2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine


    <p>2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a novel, modified nucleoside. It has antiviral activity and can be used as a building block for the synthesis of oligonucleotide analogues. 2'-O-Acetyl-3'-azido-3'-deoxy-5'-O-(p-toluoyl)-6-azauridine is a monophosphate that is phosphorylated to form an active ribonucleoside. It can be used in high purity as a building block for the synthesis of oligonucleotide analogues. This compound has been shown to have anticancer effects and DNA binding activities.</p>
    Pureza:Min. 95%

    Ref: 3D-FA144617

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  • 5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite


    <p>5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite is a nucleoside monophosphate, which is used as a synthetic building block in DNA and RNA synthesis. 5'-O-Benzoyl-2'-O-tert-butyldimethylsilyluridine 3'-CE phosphoramidite has shown anticancer activity, which may be due to its ability to inhibit the activation of oncogenes by acting as an antagonist at the cell surface. This agent also inhibits viral replication and is active against HIV, herpes simplex virus type 1, and varicella zoster virus.</p>
    Fórmula:C31H47N4O8PSi
    Pureza:Min. 95%
    Peso molecular:662.8 g/mol

    Ref: 3D-PB09101

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  • 2'-O-(2-Methoxyethyl)guanosine

    CAS:
    <p>2'-O-(2-Methoxyethyl)guanosine is a guanosine derivative isolated from the reaction of 2-aminoadenosine with methylsulfonyl chloride. This compound has been shown to react with aromatic hydrocarbons to form a reagent that is useful for the alkylation of nucleophilic groups in organic synthesis.</p>
    Fórmula:C13H19N5O6
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:341.32 g/mol

    Ref: 3D-NM57537

    1g
    483,00€
    2g
    507,00€
    5g
    1.019,00€
    10g
    1.605,00€
    500mg
    241,00€
  • 2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine

    CAS:
    <p>2’-Amino-2’-deoxy-5’-O-DMT-5-methyluridine is a novel nucleoside that has been modified to be phosphorylated on the 5' position. This modification provides the molecule with more stability in vivo and increases its anticancer potential. The synthesis of 2'-amino-2'-deoxy-5'-O-DMT-5 methyluridine is carried out by the conversion of 5'-O-(4,4'-dimethoxytrityl)-N,N-diisopropylphosphoramidite to 5'-O-(4,4'-dimethoxytrityl)-2',3',6'-triisopropylbenzoylphosphate. This compound can also inhibit viral replication by inhibiting dsRNA synthesis and is used to treat patients with chronic hepatitis B virus infection.<br>The molecule has high purity and high quality.</p>
    Pureza:Min. 95%

    Ref: 3D-NA144650

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  • N6-Carbamoylthreonyladenosine sodium salt

    CAS:
    <p>N6-Carbamoylthreonyladenosine sodium salt is a fatty acid that is found in the bacterial cell wall. It has been shown to be an essential component of the cell wall for Gram-positive and Gram-negative bacteria. N6-Carbamoylthreonyladenosine sodium salt has been used to study the mechanism of protein synthesis in bacteria, especially how enzymes are involved in this process. Chemical biology studies have shown that this molecule can bind to DNA and inhibit bacterial growth. The crystal structure of N6-Carbamoylthreonyladenosine sodium salt has also been determined using x-ray diffraction data. This molecule inhibits the binding of proteins to DNA, which prevents transcription and replication. The reaction mechanism involves hydrogen bonding between the oxygen atoms on N6-Carbamoylthreonyladenosine sodium salt and divalent metal ions such as magnesium or zinc, which are required for protein synthesis.</p>
    Fórmula:C15H19N6O8·Na
    Pureza:Min. 98 Area-%
    Cor e Forma:White Powder
    Peso molecular:434.34 g/mol

    Ref: 3D-NC06332

    2mg
    386,00€
    5mg
    660,00€
    10mg
    1.008,00€
    25mg
    2.243,00€
    50mg
    4.074,00€
  • N1,N2,N2-Trimethyl-psi-isocytidine


    <p>N1,N2,N2-Trimethylpsi-isocytidine is a novel nucleoside analog that has antiviral, anticancer, and immunosuppressive activities. It is an activator of diphosphate kinase and inhibits the formation of deoxyribonucleotides in DNA synthesis. N1,N2,N2-Trimethylpsi-isocytidine is a modified form of cytidine that contains three methyl groups. This agent has been shown to be active against human leukemic cells and can be used for the treatment of cancer and HIV infections.</p>
    Pureza:Min. 95%

    Ref: 3D-NT162881

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  • 5-Iodo-2’-C-methylcytidine

    CAS:
    <p>5-Iodo-2’-C-methylcytidine is a synthetic nucleoside that is an activator of DNA polymerases. It has been shown to be an anticancer agent and antiviral agent, with potential applications in the treatment of HIV and HBV infections. 5-Iodo-2’-C-methylcytidine is a novel monophosphate nucleoside that has been modified to improve its stability. This product is sold as a high purity, high quality, NMR grade material that can be used in research or in the manufacture of pharmaceuticals.</p>
    Fórmula:C10H14IN3O5
    Pureza:Min. 95%
    Peso molecular:383.14 g/mol

    Ref: 3D-NI162846

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  • N6-Succinyl adenosine

    CAS:
    <p>N6-Succinyl adenosine is a biochemical that is involved in the transfer of fatty acids across membranes. It has been shown to be effective in transfection experiments, where it can be used to increase the expression of genes. N6-Succinyl adenosine has also been shown to be an important substrate for various dehydrogenases. Deficiency of these enzymes leads to orotic aciduria, which is characterized by elevated levels of orotic acid in blood and urine and may lead to mental retardation. A linear calibration curve was generated for diagnosis purposes, with the enzyme activities being determined using a logistic regression model.</p>
    Fórmula:C14H17N5O8
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:383.31 g/mol

    Ref: 3D-NS16562

    1mg
    496,00€
    2mg
    706,00€
    5mg
    1.135,00€
    10mg
    1.995,00€
    25mg
    3.300,00€
  • 2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine


    <p>2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine is an antiviral nucleoside with anticancer activity. It is a synthetic analog of cytidine, modified at the 2' position with an azido group and a benzoyl group. 2'-Azido-N4-benzoyl-2'-deoxy-5'-O-DMT-cytidine has shown in vitro antiviral activity against herpes simplex virus type 1 (HSV1) and type 2 (HSV2), as well as human immunodeficiency virus type 1 (HIV1). It also has anticancer activity against human erythroblasts, leukemia cells, and lymphoma cells.</p>
    Fórmula:C37H34N6O7
    Pureza:Min. 95%
    Peso molecular:674.7 g/mol

    Ref: 3D-NA11064

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  • 2'-Deoxy-5-methylcytidine HCl

    CAS:
    <p>2'-Deoxy-5-methylcytidine HCl is a cytidine derivative that is used in the synthesis of DNA. It has been shown to have anticancer and antiviral properties, as well as being a synthetic activator for RNA polymerase. The chemical name for 2'-deoxy-5-methylcytidine HCl is 5'-[(2-bromoacetyl)amino]-2'-deoxyuridine 5'-O-(1,3-dithiole-2-thiocarbonyl)-3',5' -diiodo-. It belongs to the class of deoxyribonucleosides. This product may be used in applications such as DNA synthesis, modification of DNA, and antiviral treatment.</p>
    Fórmula:C10H15N3O4·HCl
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:277.7 g/mol

    Ref: 3D-ND08562

    1g
    490,00€
    250mg
    204,00€
    500mg
    350,00€
  • N3-Methylcytidine

    CAS:
    <p>N3-Methylcytidine is a synthetic analog of uridine. It is used for the treatment of syncytial virus infection, which is a group of diseases caused by viruses that have an RNA genome and replicate by forming syncytia—large groups of infected cells. N3-Methylcytidine inhibits the synthesis of proteins in cells and inhibits the growth of bacteria. This drug has been shown to inhibit actin polymerization and prevents cell spreading. N3-Methylcytidine also binds to RNA polymerase II and blocks its interaction with DNA, inhibiting protein synthesis at the ribosome level. N3-Methylcytidine is metabolized in vivo into methylated cytidine, which can be detected in urine samples using chemical biology methods or fluorescence resonance energy transfer (FRET) analysis. Synonyms: N3-methyluridine; 3-methyluridine</p>
    Fórmula:C10H15N3O5
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:257.24 g/mol

    Ref: 3D-NM05757

    1mg
    191,00€
    2mg
    242,00€
    5mg
    420,00€
    10mg
    554,00€
    25mg
    972,00€
  • N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine 3'-O succinate TEA


    <p>N4-Benzoyl-5'-O-DMT-2'-O-(2-methoxyethyl)cytidine 3'-O succinate TEA salt (BEDOT) is a novel nucleoside analogue that is a phosphoramidite for DNA synthesis. BEDOT has shown anticancer and antiviral activity in vitro.</p>
    Pureza:Min. 95%

    Ref: 3D-PB158799

    100mg
    134,00€
    250mg
    138,00€
    500mg
    215,00€
  • 2'-Deoxy-5'-O-DMT-N4-isobutyryl-5-methylcytidine

    CAS:
    <p>The chemical compound 2'-deoxy-5'-O-dimethyltryptophan 4-isobutyryl-5-methylcytidine is an antiviral and anticancer agent. It is a nucleoside analog that inhibits the synthesis of DNA, RNA, and proteins by inhibiting the activity of various enzymes in the cell. This agent also acts as an activator that binds to DNA, preventing transcription of genes. The modified nucleotide has been used in research to study the effects on cancer cells and HIV cells.</p>
    Pureza:Min. 95%

    Ref: 3D-ND171866

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  • 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine

    CAS:
    <p>5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine is a synthetic nucleoside that is used as a building block in the synthesis of oligonucleotides. This chemical has an electronegativity value of 1.7, which means that it is more electronegative than guanine (1.0). It also has a conjugated system and is stable under a range of conditions. 5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]-2'-deoxy-N-isobutyrylguanosine reacts with tetrazole in the presence of phosphoramidite, yielding the corresponding 5'-O-(4,4'-dimethoxytrityl)-2'-deoxy-N-isobutyrylguanosine, which can then be used to</p>
    Fórmula:C35H37N5O7
    Pureza:Min. 98 Area-%
    Cor e Forma:White Powder
    Peso molecular:639.71 g/mol

    Ref: 3D-ND02998

    10g
    291,00€
    25g
    410,00€
    50g
    594,00€
    100g
    941,00€
    250g
    1.440,00€
  • 5-Bromo-2'-deoxy-5'-O-DMT-uridine


    <p>5-Bromo-2'-deoxy-5'-O-DMT-uridine is an antiviral nucleoside that is a monophosphate analog of deoxyuridine. 5-Bromo-2'-deoxy-5'-O-DMT-uridine can be used to treat patients with leukemia and other cancers. 5-Bromo-2'-deoxy-5'-O-DMT-uridine has been shown to induce tumor cell apoptosis in vitro and in vivo, as well as inhibit the proliferation of tumor cells by blocking the synthesis of DNA. This drug also has anticancer properties, which are due to its ability to block RNA synthesis.</p>
    Fórmula:C30H29BrN2O7
    Pureza:Min. 95%
    Cor e Forma:Off-white to beige solid.
    Peso molecular:609.48 g/mol

    Ref: 3D-NB08371

    1g
    300,00€
    2g
    454,00€
    5g
    736,00€
    250mg
    134,00€
    500mg
    192,00€
  • cGMP sodium salt - Bio-X ™

    CAS:
    <p>Cyclic guanosine monophosphate (cyclic GMP) is a guanine nucleotide that is a cellular regulatory agent and is used to increase the levels of various hormones. This molecule is said to increase levels of hormones such as insulin, oxytocin and acetylcholine. Studies have found this molecule to also activate protein kinases.</p>
    Fórmula:C10H12N5O7P•Na
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:368.2 g/mol

    Ref: 3D-BG164518

    10mg
    170,00€
  • 7-[3,5-Bis-O-[(-2,4-dichlorophenyl)methyl]-2-C-methyl-b-D-ribofuranosyl]-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine

    CAS:
    <p>7-[3,5-Bis-O-[(-2,4-dichlorophenyl)methyl]-2-C-methyl-b-D-ribofuranosyl]-4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine is a synthetic nucleoside that inhibits viral DNA synthesis by interfering with the viral enzyme polymerase. It has been shown to be active against HIV and HSV and may have potential therapeutic use in antiviral therapy. 7-[3,5-Bis-O-[(-2,4-dichlorophenyl)methyl]-2-C--methyl--b--D--ribofuranosyl]-4--chloro--5--iodo--7H--pyrrolo[2,3--d]pyrimidine has been synthesized for the first time by a novel process involving deoxyribonucleosides and phosphor</p>
    Pureza:Min. 95%

    Ref: 3D-NB14088

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  • 5'-O-Methylthymidine

    CAS:
    <p>5'-O-methylthymidine is an antiviral, monophosphate nucleoside that is structurally similar to thymidine and cytidine. 5'-O-methylthymidine has been shown to inhibit the growth of cancer cells in vitro. The mechanism by which 5'-O-methylthymidine inhibits the growth of cancer cells is not known but may be due to its ability to act as a diphosphate activator or a deoxyribonucleoside phosphoramidite.</p>
    Fórmula:C11H16N2O5
    Pureza:Min. 95%
    Cor e Forma:White Off-White Powder
    Peso molecular:256.26 g/mol

    Ref: 3D-NM06451

    25mg
    254,00€
    50mg
    412,00€
    100mg
    596,00€
    250mg
    1.046,00€
    500mg
    1.995,00€
  • 3'-Deoxy-3'-fluoro-2'-C-methylguanosine

    CAS:
    <p>3'-Deoxy-3'-fluoro-2'-C-methylguanosine is a nucleoside analog that is used in the treatment of cancer. It is an activator of the anticancer drug 5-FU, which inhibits DNA synthesis and cell division. 3'-Deoxy-3'-fluoro-2'-C-methylguanosine may also be used as a starting material for the synthesis of other nucleosides, such as 2',3'-deoxyadenosine and 3',5' -deoxycytidine.</p>
    Fórmula:C11H14FN5O4
    Pureza:Min. 95%
    Peso molecular:299.26 g/mol

    Ref: 3D-ND63066

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  • 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine

    CAS:
    <p>5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is a novel synthetic nucleoside with antiviral and anticancer activities. It is a phosphoramidite that can be used to synthesize oligonucleotides of any sequence. It is a nucleoside analogue that has been shown to inhibit the activity of DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. 5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine is also an activator of viral transcription and replication.<br>5'-O-DMT-2'-O-methyl-N6-phenoxyacetyladenosine has been shown to be active against methicillin resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although it is not active against acid fast bacteria such</p>
    Fórmula:C40H39N5O8
    Pureza:Min. 95 Area-%
    Cor e Forma:Powder
    Peso molecular:717.77 g/mol

    Ref: 3D-ND04071

    1g
    258,00€
    2g
    457,00€
    250mg
    134,00€
    500mg
    192,00€
  • 2,2'-Anhydrocytidine HCl

    CAS:
    <p>2,2'-Anhydrocytidine HCl is a nucleoside for use as a DNA synthesis inhibitor</p>
    Fórmula:C9H11N3O4·HCl
    Pureza:Min. 98 Area-%
    Cor e Forma:White Powder
    Peso molecular:261.66 g/mol

    Ref: 3D-NA01967

    5g
    259,00€
    10g
    406,00€
    25g
    557,00€
    50g
    729,00€
    100g
    1.141,00€
  • 2’C-Methyl-2-thiouridine

    CAS:
    <p>2’C-Methyl-2-thiouridine is a novel nucleoside phosphoramidite that has been synthesized to serve as an activator for DNA polymerases. 2’C-Methyl-2-thiouridine is a potent antiviral agent that inhibits the replication of the hepatitis C virus in vitro. It also has antiproliferative effects against certain cancer cells and can be used as an anticancer drug. 2’C-Methyl-2-thiouridine contains a methylated thiol group, which confers a high degree of resistance to degradation by thiols, including glutathione (GSH). This compound is stable to hydrolysis and may be used in the synthesis of deoxyribonucleosides or monophosphate nucleotides.</p>
    Pureza:Min. 95%

    Ref: 3D-NM162868

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  • 2'-O-tert-Butyldimethylsilyl-5'-O-toluoyluridine 3'-CE phosphoramidite


    <p>2'-O-tert-Butyldimethylsilyl-5'-O-toluoyluridine 3'-CE phosphoramidite is a modified ribonucleotide that can be used as an activator in oligonucleotide synthesis. 2'-O-tert-Butyldimethylsilyl-5'-O-toluoyluridine 3'-CE phosphoramidite is a novel nucleoside that has antiviral and anticancer properties. It has been shown to inhibit the growth of cells by inhibiting DNA synthesis, which may be due to its ability to bind to DNA and inhibit DNA polymerase. The CAS number for this product is 126214-01-3.</p>
    Fórmula:C32H49N4O8PSi
    Pureza:Min. 95%
    Peso molecular:676.83 g/mol

    Ref: 3D-PB08946

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  • 8-Thioguanosine

    CAS:
    <p>8-Thioguanosine is a purine derivative with reactive chlorine atoms. It has been shown to be a potent inhibitor of cellular targets, including monoclonal antibodies, growth factors, and transcription-polymerase chain reactions (PCR). 8-Thioguanosine binds to the antibody response by modulating the function of the B cells. This drug also has immunomodulatory effects that have been shown in animal models. 8-Thioguanosine is used as an immunosuppressant in patients undergoing bone marrow transplants and solid organ transplants.</p>
    Fórmula:C10H13N5O5S
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:315.3 g/mol

    Ref: 3D-NT07601

    10mg
    229,00€
    25mg
    367,00€
    50mg
    515,00€
    100mg
    809,00€
    250mg
    1.141,00€
  • 2'-Deoxy-5'-O-DMT-cytidine

    CAS:
    <p>2'-Deoxy-5'-O-DMT-cytidine is an organic compound. It is a synthetic, combinational and amine nitrogen containing heterocyclic compound that is used in organic synthesis. This chemical is also used as a building block for the synthesis of heterocyclic compounds with other functional groups such as thionyl, formulae, chlorides and hydrogen atoms.</p>
    Fórmula:C30H31N3O6
    Pureza:Min. 95 Area-%
    Cor e Forma:White Powder
    Peso molecular:529.58 g/mol

    Ref: 3D-ND57360

    1g
    254,00€
    250mg
    135,00€
    500mg
    178,00€
  • Acetyl coenzyme A sodium salt

    CAS:
    <p>Acetyl-coenzyme A is an important intermediate in the metabolism of carbohydrates, fats, and proteins. It is a cytosolic molecule that is synthesized from Acetyl-CoA and ATP. The Michaelis–Menten kinetics describe the relationship between the concentration of acetyl-coenzyme A and the rate of its consumption. Acetyl co-enzyme A is found in many different tissues, including plants, animals, and humans. It has an important role in regulating cellular growth and differentiation by activating various enzymes involved in metabolic pathways. Acetyl CoA can be acetylated to form acetyl CoA carboxylic acid (ACC) which then turns into malonyl CoA through a series of reactions. Malonyl CoA then enters the Krebs cycle as a key intermediate for generating energy from fatty acids.</p>
    Fórmula:C23H38N7O17P3S·xNa
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:809.57 g/mol

    Ref: 3D-NA15698

    1g
    5.299,00€
    5mg
    294,00€
    100mg
    1.530,00€
    250mg
    2.245,00€
    500mg
    3.455,00€
  • 3'-O-Acetyl-5'-tert-butyldiphenylsilyl-2'-deoxy-2'-fluoro-5-methyluridine


    <p>3'-O-Acetyl-5'-tert-butyldiphenylsilyl-2'-deoxy-2'-fluoro-5-methyluridine is a synthetic nucleoside that has antiviral activity. It is a modified nucleoside that contains a monophosphate group, which makes it an activator of DNA polymerase. 3'-O-Acetyl-5'-tert-butyldiphenylsilyl-2'-deoxy-2'-fluoro-5-methyluridine is novel because it contains an acetyl group at the 3' position and a silyl ether on the 2' oxygen atom. 3'-O-Acetyl-5'-tert-butyldiphenylsilyl-2'-deoxy-2'-fluoro -5 -methyluridine has CAS No. 62768‑36‑3 and is available in high purity.</p>
    Pureza:Min. 95%

    Ref: 3D-NA158762

    2g
    135,00€
    5g
    137,00€
    10g
    214,00€
  • 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine

    CAS:
    <p>2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine is a modified nucleoside that has antiviral, anticancer and antimalarial activities. This compound has been synthesized as a monophosphate derivative of the natural nucleoside uridine. It is an activator of DNA polymerase, which helps to synthesize DNA in cells. 2'-O-Acetyl-3'-deoxy-3'-fluoro-5-methoxy-5'-O-toluoyluridine also has anticancer activity due to its ability to inhibit the replication of the human tumor virus KSHV.</p>
    Pureza:Min. 95%

    Ref: 3D-NA162875

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  • 5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine


    <p>5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine is a novel nucleoside that is synthesized from ribonucleosides. It is an inhibitor of the RNA polymerase enzyme, which prevents the transcription and replication of DNA. 5'-O-Benzoyl-2',3'-dideoxy-3'-fluorouridine also inhibits viral DNA synthesis by preventing viral RNA from being translated into DNA. This product has been shown to be active against a wide range of viruses, including influenza A virus, herpes simplex virus type 1, and vaccinia virus.</p>
    Fórmula:C16H15FN2O5
    Pureza:Min. 95%
    Peso molecular:334.35 g/mol

    Ref: 3D-NB08204

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  • 3’-Deoxy-3’-fluoro-6-thioinosine

    CAS:
    <p>Please enquire for more information about 3’-Deoxy-3’-fluoro-6-thioinosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Pureza:Min. 95%

    Ref: 3D-FD144669

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  • 9-(2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyl-b-D-ribofuranosyl)-6-phenylpurine


    <p>9-(2'-O-Acetyl-3'-deoxy-3'-fluoro-5'-O-toluoyl-b-D-ribofuranosyl)-6-phenylpurine (FTC) is a novel antiviral nucleoside analog that inhibits the synthesis of DNA by inhibiting the enzyme DNA polymerase. It has been shown to be effective against HIV in vitro. FTC exhibits anticancer activity through inhibition of DNA synthesis and induction of apoptosis. FTC also has high purity and quality, as it is synthesized chemically without any purification steps.</p>
    Pureza:Min. 95%

    Ref: 3D-NA162839

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  • EdU

    CAS:
    <p>2'-Deoxy-5-ethynyluridine (5-EdU) is a modified thymidine analogue containing a terminal alkyne group, which is used for nucleotide labelling. 5-Edu is easily taken up by cells and incorporated by metabolic activation during DNA synthesis. By adding an azide conjugated to a fluorophore or a biotin moiety, a click reaction occurs from the labelled nucleotide linked by a triazole group. 5-Edu are employed in cell proliferation assays, to study DNA and RNA localisation, structure and dynamics, in the synthesis of aptamers with the click-SELEX method, and in other applications such as the preparation of oligonucleotide microarrays and nanoelectronic devices.</p>
    Fórmula:C11H12N2O5
    Pureza:Min. 98 Area-%
    Cor e Forma:Powder
    Peso molecular:252.23 g/mol

    Ref: 3D-NE08701

    1g
    394,00€
    5g
    1.002,00€
  • 2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine

    CAS:
    <p>2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine is a nucleoside that is synthesized from 2'-deoxyribonucleosides and activated with diphosphate. It is an antiviral and anticancer agent that inhibits viral DNA polymerases, leading to the inhibition of viral replication. 2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine has also been shown to inhibit cancer cell growth in vitro by inhibiting the synthesis of cellular DNA. This nucleoside has high purity and quality as it is made synthetically and has novel properties because it contains modified groups.</p>
    Fórmula:C35H37N5O7
    Pureza:Min. 95%
    Cor e Forma:White to off-white solid.
    Peso molecular:639.71 g/mol

    Ref: 3D-ND08416

    5mg
    135,00€
    10mg
    178,00€
    25mg
    214,00€
    50mg
    358,00€
  • 2'-Deoxy-5-fluorouridine

    CAS:
    <p>2'-Deoxy-5-fluorouridine is a nucleoside analog that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. It has been shown to inhibit the growth of cancer cells and induce apoptosis in vivo. 2'-Deoxy-5-fluorouridine has also been shown to inhibit tumor growth in animal models by inhibiting the production of reactive oxygen species and upregulating tumor suppressor genes, such as p53. This drug also has inhibitory effects on enzymes that are involved in cell proliferation, such as protein kinase C and tyrosine kinases. 2'-Deoxy-5-fluorouridine is metabolized by water vapor, so it must be administered with a humidifier or nebulizer. 2'-Deoxy-5-fluorouridine may cause side effects such as nausea, vomiting, and diarrhea.</p>
    Fórmula:C9H11FN2O5
    Pureza:Min. 98 Area-%
    Cor e Forma:White Off-White Powder
    Peso molecular:246.2 g/mol

    Ref: 3D-ND02921

    10g
    405,00€
    25g
    738,00€
    50g
    1.170,00€
    100g
    1.993,00€
    250g
    4.268,00€
  • N-Boc-5'-chloro-5'-deoxy-2,3-O-isopropylideneadenosine


    <p>N-Boc-5'-chloro-5'-deoxy-2,3-O-isopropylideneadenosine is a novel nucleoside phosphoramidite. It is synthesized by the reaction of 5'-chloro-5'-deoxyadenosine with 2,3-O-isopropylideneadenosine in the presence of tetrazole and triethylammonium tetrafluoroborate. This compound has been shown to be an activator against the ribonucleotide reductase enzyme, which is involved in the synthesis of DNA. N-Boc-5'-chloro-5'-deoxyadenosine also has antiviral activity against human cytomegalovirus and influenza A virus.</p>
    Pureza:Min. 95%

    Ref: 3D-NB46266

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  • 3'-O, N4-Diacetyl-2'-deoxycytidine


    <p>3'-O, N4-Diacetyl-2'-deoxycytidine is a modified nucleoside that has anticancer and antiviral activities. It inhibits the synthesis of DNA by preventing the formation of deoxyribonucleotide triphosphates. 3'-O, N4-Diacetyl-2'-deoxycytidine is a novel nucleoside with high purity and high quality. The CAS number for this product is 61428-37-5. This product can be used as starting material in the synthesis of phosphoramidites or modified oligonucleotides.</p>
    Fórmula:C13H17N3O6
    Pureza:Min. 95%
    Peso molecular:311.29 g/mol

    Ref: 3D-ND09207

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  • 4-Demethylwyosine

    CAS:
    <p>4-Demethylwyosine is a metabolite found in the bacterium Pyrococcus furiosus. It is an intermediate in the biosynthesis of 2-amino-3,5-dimethyoxybenzoic acid. 4-Demethylwyosine has been shown to inhibit cancer cell proliferation by inhibiting the synthesis of lysine residues and base formation. This inhibition may be due to its methyl transferase activity, which leads to decreased levels of methionine, or it may be due to its ability to act as a carboxylate group donor. 4-Demethylwyosine has also been shown to bind with DNA and RNA, regulating posttranscriptional processes such as protein translation and transcription.</p>
    Fórmula:C13H15N5O5
    Pureza:Min. 80 Area-%
    Cor e Forma:Powder
    Peso molecular:321.29 g/mol

    Ref: 3D-ND159486

    1mg
    349,00€
    2mg
    478,00€
    5mg
    906,00€
    10mg
    1.019,00€
    500µg
    243,00€
  • N1-Methylguanosine

    Produto Controlado
    CAS:
    <p>N1-Methylguanosine is a methylated nucleotide that is incorporated into the growing DNA chain during protein synthesis. The incorporation of N1-methylguanosine into the growing DNA chain can cause frameshifting, which creates an unusual amino acid sequence. This effect has been shown in model organisms, such as Saccharomyces cerevisiae and Escherichia coli. In these organisms, N1-methylguanosine has been shown to induce cancer when added to the growth medium. It is also found in urine samples from people with bladder cancer and has been used to identify urinary tract cancers. Titration calorimetry studies have shown that N1-methylguanosine binds to a chelate ligand and forms a disulfide bond with cysteine residues on proteins or peptides, which may lead to mitochondrial dysfunction by interfering with hydrogen bonding interactions. Messenger RNA studies show that N1-methylguanosine inhibits translation of mRNA by binding to</p>
    Fórmula:C11H15N5O5
    Pureza:Min. 95%
    Cor e Forma:White Powder
    Peso molecular:297.27 g/mol

    Ref: 3D-NM08574

    5mg
    285,00€
    10mg
    396,00€
    25mg
    652,00€
    50mg
    915,00€
    100mg
    1.278,00€
  • 5'-O-Benzoyl-2'-deoxyinosine 3'-CE phosphoramidite


    <p>5'-O-Benzoyl-2'-deoxyinosine 3'-CE phosphoramidite is an anticancer and antiviral agent. It is a nucleoside analogue that inhibits the synthesis of DNA by competitive inhibition of ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. The monophosphate form also inhibits viral replication by inhibiting reverse transcriptase. This compound has been shown to be active against herpes simplex virus type 1 and 2, adenovirus, influenza A virus, and vaccinia virus.</p>
    Fórmula:C26H33N6O6P
    Pureza:Min. 95%
    Peso molecular:556.56 g/mol

    Ref: 3D-PB09098

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  • 1,3-Dimethylpseudouridine

    CAS:
    <p>1,3-Dimethylpseudouridine is a methylated derivative of pseudouridine, which is a naturally occurring modified nucleoside found in RNA. This compounds can be used in research applications</p>
    Fórmula:C11H16N2O6
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:272.25 g/mol

    Ref: 3D-ND162827

    5mg
    277,00€
    10mg
    434,00€
    25mg
    731,00€
  • 2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate


    <p>2'-O-(2-Methoxyethyl)-5-methylcytidine 5'-monophosphate is a novel nucleoside analog that is phosphorylated to its active form, 5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine monophosphate, which has antiviral and anticancer properties. It can be used as an activator for oligonucleotide synthesis and DNA synthesis. This product is available in high purity (&gt;98%) and high quality. CAS No.: 181297-76-7</p>
    Pureza:Min. 95%

    Ref: 3D-NM71850

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  • Adenosine 2',3'-cyclic monophosphate sodium

    CAS:
    <p>Adenosine 2',3'-cyclic monophosphate sodium (AMP-Na) is a chemical compound that is found in Streptomyces coelicolor. It has been shown to have an active role in the biotechnology industry for research and development. AMP-Na inhibits the synthesis of carbohydrates by binding to enzymes such as adenosyl-l-methionine peroxidase, which is involved in the metabolism of carbohydrates. Adenosine 2',3'-cyclic monophosphate sodium also has a long half-life, which makes it useful for therapeutic purposes.</p>
    Fórmula:C10H11N5NaO6P
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:351.19 g/mol

    Ref: 3D-NA07178

    1g
    2.432,00€
    50mg
    357,00€
    100mg
    546,00€
    250mg
    1.086,00€
    500mg
    1.627,00€
  • 6-Amino-4-hydrazino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine


    <p>6-Amino-4-hydrazino-1-(b-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine is a nucleoside phosphoramidite which is used in the synthesis of oligonucleotides. It is a novel modified nucleoside and has antiviral and anticancer activities. 6-Amino-4-hydrazino-1-(b-D ribofuranosyl)-1H pyrazolo[3,4 d]pyrimidine can be used as an activator for 2'-deoxyribonucleotide synthesis and an inhibitor of ribonucleotide synthesis.</p>
    Pureza:Min. 95%

    Ref: 3D-NA162943

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  • 5-Methylcytidine-5'-monophosphate

    CAS:
    <p>5-Methylcytidine-5'-monophosphate is a nucleotide that is an intermediate in the synthesis of DNA. It is a neutral form and has been sequenced. 5-Methylcytidine-5'-monophosphate is found in cellular components, such as mitochondria and nuclei. The biochemical properties of this molecule are dependent on its methylation state. This molecule also plays a role in mitochondrial functions and nuclear DNA modifications.</p>
    Fórmula:C10H16N3O8P
    Pureza:Min. 95%
    Cor e Forma:White Off-White Powder
    Peso molecular:337.22 g/mol

    Ref: 3D-NM29555

    1mg
    254,00€
    2mg
    382,00€
    5mg
    543,00€
    10mg
    804,00€
    25mg
    1.516,00€
  • 1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt


    <p>1-(2'-Deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)thymine 3'-O-succinate triethylammonium salt is a compound used in the synthesis of oligonucleotides. The synthesis of such compounds often involves the use of protecting groups, such as the 4,4'-dimethoxytrityl (DMT) group, to prevent unwanted reactions during the synthesis process. The 2'-fluoro modification is of particular interest due to its potential to alter the chemical and biological properties of the resulting oligonucleotides. Fluorinated nucleosides and their analogs have been extensively studied for their antiviral and anticancer activities</p>
    Fórmula:C35H34FN2O10·C6H16N
    Pureza:Min. 95%
    Peso molecular:763.87 g/mol

    Ref: 3D-ND09138

    10mg
    135,00€
    25mg
    135,00€
    50mg
    194,00€
    100mg
    290,00€
    250mg
    497,00€
  • N6-Benzoyl-9-(3'-O-methyl-b-D-xylofuranosyl)adenine


    <p>N6-Benzoyl-9-(3'-O-methyl-β-D-xylofuranosyl)adenine is a novel nucleoside containing an aromatic ring that is attached to the 9 position of the adenine base. This compound has shown anticancer and antiviral properties in vitro and in vivo. It has been used as a building block for RNA and DNA synthesis, and phosphoramidites for DNA synthesis. N6-Benzoyl-9-(3'-O-methyl-β-D-xylofuranosyl)adenine is also a potent activator of ribonucleotide reductase, which converts ribonucleotides into deoxyribonucleotides.</p>
    Pureza:Min. 95%

    Ref: 3D-NB137578

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  • 5-b-D-Glucopyranosyl-5-thio-thymine


    <p>5-b-D-Glucopyranosyl-5-thio-thymine is a novel, synthetic nucleoside that has antiviral activity. It is deoxyribonucleosides and ribonucleosides, which are the building blocks of DNA and RNA respectively. 5-b-D-Glucopyranosyl-5-thio-thymine can be used as an activator for phosphoramidites, which are used in the synthesis of DNA and RNA. This modified nucleotide also has anti cancer properties as it inhibits the growth of tumor cells.</p>
    Pureza:Min. 95%

    Ref: 3D-NG58691

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  • 4’-C-Methyl-5-methylcytidine

    CAS:
    <p>4’-C-Methyl-5-methylcytidine is a phosphoramidite nucleoside that is used as a reagent in the synthesis of DNA. It is modified with a 4′-methyl and 5′-methyl group at the C4 and C5 positions of the cytosine base, respectively. The 4′-C methyl group is an antiviral agent that inhibits viral replication by inhibiting reverse transcriptase. The 5′-methyl group prevents deamination of cytosine residues by inhibiting uracil glycosylase. This product has anticancer properties due to its ability to inhibit cell division and activate apoptosis in tumor cells.</p>
    Pureza:Min. 95%

    Ref: 3D-NM163132

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  • 1-(2’-Deoxy-2’-fluoro-b-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil

    CAS:
    <p>1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil is a novel, anticancer drug. It is active against both RNA and DNA viruses, such as HIV, influenza virus and herpes virus. 1-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-N3-(2S)-(2-amino-3-carbonyl]propyluracil has been shown to be an activator for phosphoramidites in aqueous solution. This compound is of high purity with CAS No. 2072145–25–4. It is also a synthesized, monophosphate nucleoside that can be used in the production of modified nucleosides for therapeutic purposes or as antiviral agents</p>
    Pureza:Min. 95%

    Ref: 3D-ND162854

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