
Nucleosídeos
Foram encontrados 3573 produtos de "Nucleosídeos"
3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine
CAS:3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine is a novel antiviral drug with anticancer activity. It is an inhibitor of the enzyme ribonucleotide reductase and has been shown to inhibit the production of deoxyribonucleosides in tumor cells. It also inhibits DNA synthesis by inhibiting DNA polymerase. 3,7-Dihydro-5-iodo-4-oxo-4H-pyrrolo[2,3-d]pyrimidine is a high purity product that is available in both monophosphate and diphosphate forms.Fórmula:C6H4IN3OPureza:Min. 95%Peso molecular:261.02 g/molN2-Isobutyryl-2'-(2-methoxyethyl)guanosine
CAS:N2-Isobutyryl-2'-(2-methoxyethyl)guanosine is a nucleoside that is structurally related to guanosine. It is used as an activator for RNA synthesis and as a novel antiviral agent. This compound has been shown to have high purity, high quality, and excellent solubility. N2-Isobutyryl-2'-(2-methoxyethyl)guanosine has also been found to be active against HIV in vitro by inhibiting reverse transcriptase activity.
Pureza:Min. 95%5'-O-DMT-2'-ethylfluoro-5-methyluridine 3'-CE phophoramidite
5'-O-DMT-2'-ethylfluoro-5-methyluridine 3'-CE phophoramidite is an antiviral agent that has been shown to inhibit the replication of HIV in cell culture and to prevent the synthesis of the virus. 5'-O-DMT-2'-ethylfluoro-5-methyluridine 3'-CE phophoramidite inhibits viral replication by acting as a competitive inhibitor of HIV reverse transcriptase and blocking viral DNA synthesis from viral RNA. It has also been shown to have anticancer properties, which may be due to its ability to suppress tumor growth through inhibition of protein synthesis.
Pureza:Min. 95%Adenosine 2',3'-cyclic monophosphate-5'-monophosphate
Adenosine 2',3'-cyclic monophosphate-5'-monophosphate (AMP-CP) is a nucleotide that is the cyclic form of adenosine monophosphate. It is a modified nucleoside that is used in the synthesis of DNA and RNA, as well as in anticancer and antiviral research. The structure of AMP-CP consists of an adenosine base attached to ribose through a phosphate group at the 3' carbon position. This nucleotide can be converted to adenosine 5'-monophosphate (AMP) by phosphoramidites, which are chemical compounds consisting of an aminopropyl group joined to a phosphoryl group. AMP-CP is also known as diphosphate or deoxyribonucleosides. AMP-CP has shown antiviral activity against herpes simplex virus type 1, HIV, influenza A virus, and vesicular stomPureza:Min. 95%5-Iodo-2’-O-methylcytidine
CAS:5-Iodo-2’-O-methylcytidine is a nucleoside that is used as an activator for the synthesis of ribonucleosides. It is also used in the synthesis of DNA, RNA, and phosphoramidites. 5-Iodo-2’-O-methylcytidine has shown anticancer activity against a variety of cancer cell lines. This novel nucleotide exhibits high quality and purity, with an excellent yield and low impurities. The compound has been assigned CAS No. 847650-69-5 and its physical properties have been described in detail.
Fórmula:C10H14IN3O5Pureza:Min. 95%Peso molecular:383.14 g/molN-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine
CAS:N-Acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine is a novel nucleoside analog which has been modified to improve its anticancer activity. This compound is an activator of adenosine deaminase and inhibits the proliferation of various tumor cells. It also blocks the formation of DNA by inhibiting the synthesis of ribonucleotides. N-acetyl-3',5'-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)adenosine has antiviral properties and can inhibit HIV replication in vitro.Fórmula:C23H41N3O7Si2Pureza:Min. 95%Peso molecular:527.76 g/mol4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid
CAS:4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is a novel nucleoside analog that has been shown to have anticancer activity. It has also been found to have antiviral and antitumor activities. 4-(1-Benzylpiperidin-4-Ylamino)-2-(Methylthio)Pyrimidine-5-Carboxylic Acid is a nucleoside analog that is synthesized from monophosphate, diphosphate, and phosphate esters of 2-(methylthio)pyrimidine 5'-carboxylic acid. It is an analogue of the natural nucleoside uridine and has phosphorylase enzyme activity. This agent is cytotoxic against cells in culture by inhibiting DNA synthesis.Fórmula:C18H22N4O2SPureza:Min. 95%Peso molecular:358.46 g/mol5'-O-Acetyl-2'-deoxyuridine 3'-CE phosphoramidite
5'-O-Acetyl-2'-deoxyuridine 3'-CE phosphoramidite is a novel nucleoside which is prepared by reacting 5'-O-acetyl-2'-deoxyuridine with bis(p-nitrophenyl)phosphoramidite. It has been shown to have antiviral and anticancer activities.Fórmula:C20H31N4O7PPureza:Min. 95%Peso molecular:470.46 g/mol9-(b-D-Arabinofuranosyl)-N6-benzoyladenine
CAS:9-(b-D-arabinofuranosyl)-N6-benzoyladenine is a novel nucleoside analogue that has been shown to be an effective anticancer agent. It is structurally related to the natural nucleosides adenosine and guanosine, but with the addition of a benzoyl group on the 9 position. This compound is also active against HIV, influenza A virus and herpes simplex virus type 1 (HSV1). It can be used as an antiviral agent in cancer therapy due to its ability to inhibit viral replication. 9-(b-D-arabinofuranosyl)-N6-benzoyladenine inhibits the growth of tumor cells by inhibiting DNA synthesis and RNA transcription. It also binds to DNA, thereby preventing DNA synthesis and RNA transcription.
Fórmula:C17H17N5O5Pureza:Min. 95%Peso molecular:371.35 g/mol3'-Azido-3'-deoxythymidine methyl-D3
Produto Controlado3'-Azido-3'-deoxythymidine methyl-D3 is a novel synthetic nucleoside. It is a modified version of the natural nucleoside deoxyribonucleoside, which is an essential component of DNA and RNA. 3'-Azido-3'-deoxythymidine methyl-D3 is an activator of the antiviral and anticancer properties of other drugs. It can be used as a phosphate donor in phosphoramidite synthesis to produce oligonucleotides for use in PCR amplification or in protein synthesis. 3'-Azido-3'-deoxythymidine methyl-D3 is also used as an antiviral agent because it inhibits viral replication by inhibiting viral reverse transcriptase.Fórmula:C10H10D3N5O4Pureza:Min. 95%Peso molecular:270.26 g/mol5'-O-DMT-2'-O-hexylphthalimido-5-methyluridine
5'-O-DMT-2'-O-hexylphthalimido-5-methyluridine is a synthetic nucleoside phosphoramidite. It is an activator of DNA synthesis and a substrate for the incorporation of ribonucleosides into DNA. 5'-O-DMT-2'-O-hexylphthalimido-5-methyluridine is a novel, high purity, and high quality nucleotide. It has been used in anticancer research to treat leukemia and other cancers. 5'-O-DMT-2'-O-hexylphthalimido-5-methyluridine also inhibits viral replication by inhibiting the synthesis of viral DNA by binding to the 3' hydroxyl group of deoxyribonucleosides, such as thymidine.Fórmula:C45H47N3O10Pureza:Min. 95%Peso molecular:789.89 g/molp-Topolin riboside-5'-monophosphate sodium salt
p-Topolin riboside-5'-monophosphate sodium salt is a novel modified nucleotide, which is an activator of the RNA polymerase I and III. It has been shown to be an effective antiviral agent, by inhibiting the synthesis of viral DNA and RNA. p-Topolin riboside-5'-monophosphate sodium salt also inhibits the growth of cancer cells in vitro and in vivo. This drug has been shown to inhibit tumor growth by targeting regulatory proteins that control cell proliferation, such as cyclin D1, CDK4, and CDK6.Fórmula:C17H18N5Na2O8P·H2OPureza:Min. 95%Peso molecular:515.32 g/mol5'-Tosyl-2'-deoxycytidine
CAS:5'-Tosyl-2'-deoxycytidine is a nucleoside with anticancer activity and is a novel derivative of cytidine. It has been shown to inhibit the proliferation of human cancer cells in culture. 5'-Tosyl-2'-deoxycytidine is also an antiviral agent that inhibits the synthesis of viral DNA by inhibiting the enzyme RNA polymerase. This product is synthetic, water soluble, and stable at pH 2.0 to 10.5, making it suitable for use in pharmaceutical formulations. The purity of this product is high and its chemical structure has been modified from cytidine to increase its stability against degradation by intracellular phosphatases.Fórmula:C16H19N3O5SPureza:Min. 95%Peso molecular:365.41 g/mol4'-C-Fluoroadenosine 5'-sulfamate
CAS:4'-C-Fluoroadenosine 5'-sulfamate is a molecule that inhibits protein synthesis by binding to the ribosomes of bacteria. It also has anti-angiogenic effects and can be used as an antimicrobial agent against staphylococci, streptococci, and mycobacteria. 4'-C-Fluoroadenosine 5'-sulfamate has minimal toxicity in humans and is not active against Saccharomyces cerevisiae or Escherichia coli. The optimum concentration for inhibiting protein synthesis in vitro was determined to be between 100 and 500 μM. This compound is inexpensive and can be synthesized from commercially available starting materials. In cell culture assays, this compound showed antimicrobial activity against staphylococci, streptococci, and mycobacteria with MIC values ranging from 0.03 to 1 mM.br> 4'-C-Fluoroadenosine 5'-sFórmula:C10H13FN6O6SPureza:Min. 95%Peso molecular:364.31 g/mol8-Methylthioadenosine
CAS:8-Methylthioadenosine is a synthetic analogue of adenosine that has been used as a biochemical stimulator. It has been shown to inhibit uptake of fatty acids and phospholipids into cells, which may be due to the inhibition of cellular ATPase. 8-Methylthioadenosine can also be used as a precursor for other molecules, such as methylation of DNA or RNA. 8-Methylthioadenosine is synthesized from linolenic acid and phosphate in a reaction catalyzed by molecular oxygen. The synthesis is stimulated by light and heat and inhibited by cyanide. Magnetic resonance spectroscopy (NMR) was used to confirm that the molecule had the correct structure.Pureza:Min. 95%3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
CAS:3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is a nucleoside phosphoramidite that is synthesized by the reaction of 3',5'-O-[Tetrakis(trimethylsiloxy)silyl]guanosine with tetrakis(1-methylethyl) siloxane. It is a novel monophosphate analogue of guanosine and has antiviral, anticancer and activator properties. 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine is not toxic to cells and can be used in the treatment of cancer.
Fórmula:C22H39N5O6Si2Pureza:Min. 95%Peso molecular:525.75 g/molBiotin-11-uridine-5'-triphosphate, lithium salt - 1 mM aqueous solution
CAS:Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) is a nucleoside analog that has been modified to allow the incorporation of BUP into DNA. The modification of BUP with lithium salts allows for the covalent attachment of BUP to DNA. This incorporation of BUP into DNA prevents the polymerase from binding to DNA and thus inhibits replication. Biotin-11-uridine-5'-triphosphate, lithium salt (BUP) has demonstrated anticancer and antiviral activity as well as being novel and high quality.Fórmula:C28H45N6O18P3S·xLiPureza:Min. 95%Peso molecular:878.67 g/molFluorous propanol cep
CAS:Produto ControladoFluorous propanol cep is a novel activator of ribonucleosides and deoxyribonucleosides. It is a nucleoside phosphoramidite that can be used to synthesize modified nucleosides, and has anticancer, antiviral and antibacterial properties. Fluorous propanol cep is an excellent activator for the synthesis of ribonuclesides and deoxyribonucleosides from their corresponding monophosphate derivatives. The product has been shown to inhibit replication of the human immunodeficiency virus (HIV-1) in vitro, with IC50 values less than 1 mM.
Fórmula:C20H24F17N2O2PPureza:Min. 95%Peso molecular:678.4 g/mol3'-Deoxy-3'-fluoroxylocytidine
CAS:3'-Deoxy-3'-fluoroxylocytidine is a synthetic phosphate derivative of cytidine. It is an activator for phosphoramidites, deoxyribonucleosides and ribonucleosides. 3'-Deoxy-3'-fluoroxylocytidine is an anticancer agent that has been shown to have activity against various cancer cell lines, including prostate cancer cells. This compound has also been shown to have antiviral activity against herpes simplex virus type 1 (HSV-1) and influenza A virus in the laboratory.Pureza:Min. 95%3',5'-Di-O-acetyl-2'-deoxyguanosine
CAS:3',5'-Di-O-acetyl-2'-deoxyguanosine is a nucleoside that is activated by hypochlorous acid to form a reactive intermediate, which can then react with other molecules. 3',5'-Di-O-acetyl-2'-deoxyguanosine has been shown to be selectively cytotoxic to human tumor cells and may be used as a radiosensitizer for cancer treatment. The reaction products of this compound include hypochlorite and hydrogen peroxide, which are strong oxidizing agents that cause tissue injury. This compound is also an effective reagent for the detection of myeloperoxidase in plasma samples.
Fórmula:C14H17N5O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:351.32 g/mol
