Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3571 produtos de "Nucleosídeos"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
6-[(4-Nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine-5'-monophosphate disodium salt
CAS:6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is a modified nucleoside that has anticancer activity. It is phosphorylated to the corresponding nucleotide in vivo and inhibits the growth of cancer cells. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt has a novel structure and can be used as an activator for ribonucleotides or deoxyribonucleotides. It is also used as a component in DNA synthesis, which may be due to its ability to inhibit viral RNA replication. This drug can be synthesized through chemical reactions that involve diphosphate, nucleosides, and phosphoramidites. 6-[(4-Nitrobenzyl)thio]purine-5'-monophosphate disodium salt is not currently available on the market; however, it canFórmula:C17H16N5Na2O9PSPureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:543.36 g/mol2,2’-Anhydro-5’-O-DMT-5-methyluridine
CAS:2,2’-Anhydro-5’-O-DMT-5-methyluridine is an anhydro nucleosideFórmula:C31H30N2O7Pureza:Min. 95%Peso molecular:542.58 g/mol(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol hydrochloride
CAS:(1S,4R)-4-(2-Amino-6-chloro-9H-purin-9-yl)-2-cyclopentene-1-methanol HCl is an activator of DNA polymerase. It is a novel modified deoxyribonucleosides and nucleosides that has antiviral, anticancer and antifungal activities. It can be used in the treatment of various diseases such as HIV, cancer and chronic hepatitis B virus infection.Fórmula:C11H12ClN5O•HClPureza:Min. 95%Peso molecular:302.16 g/mol2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-O-succinate
CAS:2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-O-succinate is a nucleoside that is modified by the incorporation of an isobutyryl group at the 2' position. It has shown to be an activator of phosphoramidites and can be used as a precursor for the synthesis of nucleic acids, including DNA and RNA. 2'-Deoxy-5'-O-DMT-N2-isobutyrylguanosine 3'-O-succinate has been shown to have anticancer properties, antiviral properties, and antiinflammatory properties.Fórmula:C39H41N5O10Pureza:Min. 95%Peso molecular:739.77 g/mol5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methyl-2-(1-methylethyl)cyclohexyl ester
CAS:5-(4-Amino-5-fluoro-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane-2-carboxylic acid 5-methylcyclohexyl ester is a novel nucleoside analog with antiviral and anticancer properties. It is an inhibitor of influenza virus replication. The compound is also active against human DNA polymerase beta, herpes simplex virus type 1 and 2, and Epstein Barr virus. This compound is synthesized as a phosphate derivative for use in phosphoramidite chemistry for the synthesis of DNA or RNA.Fórmula:C18H26FN3O4SPureza:Min. 95%Peso molecular:399.48 g/mol3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine
3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT-uridine is a novel, modified nucleoside. This product is an activator of the ribonucleotide reductase enzyme and is used as a precursor in the synthesis of deoxyribonucleosides. It has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. It has also been shown to have anticancer properties, as it inhibits DNA synthesis and tumor cell proliferation without affecting healthy cells. 3'-O-Acetyl-5-benzylaminocarbonyl-2'-O-methyl-5'-O-DMT uridine is synthesized from 5-(3,4,5)-trimethoxybenzaldehyde, 2′(2,6 dichloro)amino]methyl]benzeneacetic acid methyl ester and 5Pureza:Min. 95%2'-C-Methyluridine 5'-triphosphate lithium salt - 10mM aqueous solution
2'-C-Methyluridine 5'-triphosphate lithium salt is a nucleoside that is a high quality, activator and novel. It is used to synthesize ribonucleosides and deoxyribonucleosides. This drug has anticancer properties and can be used as an immunomodulator. 2'-C-Methyluridine 5'-triphosphate is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex.Fórmula:C10H13N2O15P3Li4Pureza:Min. 95%Peso molecular:521.9 g/mol3'-Deoxy-3'-fluorothymidine-5'-triphosphate sodium salt
3'-Deoxy-3'-fluorothymidine-5'-triphosphate sodium salt (3'-DFP) is a modified nucleoside that acts as an antiviral and anticancer drug. It is a monophosphate derivative of thymidine, which is converted to diphosphate by the enzyme thymidylate kinase. 3'-DFP inhibits DNA synthesis by preventing the incorporation of deoxyribonucleotides into DNA. 3'-DFP can also be used as a building block in the synthesis of other nucleosides such as cytidine 5′-triphosphate, uridine 5′-triphosphate, and adenosine 5′-triphosphate. 3'-DFP is active against herpesviruses including Epstein-Barr virus, cytomegalovirus, and varicella zoster virus. It has also been shown to inhibit cancer cell proliferation when used at high doses.Pureza:Min. 95%2-Deoxycytidine 3',5'-diphosphate
CAS:2-Deoxycytidine 3',5'-diphosphate is an additive that is used in the production of DNA. It is a single-stranded nucleotide with a guanine base. 2-Deoxycytidine 3',5'-diphosphate has been shown to inhibit bacterial growth by reacting with hydrogen peroxide, which is produced during the process of oxidative phosphorylation. This reaction leads to the formation of reactive oxygen species, which damage DNA and cause cell death. The compound also binds to metal ions and prevents them from interacting with cellular components. 2-Deoxycytidine 3',5'-diphosphate can be used as a chromatographic agent for separating DNA fragments according to their size.
Fórmula:C9H15N3O10P2Pureza:Min. 95%Peso molecular:387.18 g/mol7-Deaza-2'-deoxy-5'-O-DMT-xanthosine
CAS:7-Deaza-2'-deoxy-5'-O-DMTxanthosine is a nucleoside analog with antiviral properties. It is an activator of the phosphoramidites and can be used in the synthesis of high quality, high purity, and novel nucleosides. 7-Deaza-2'-deoxy-5'-O-DMTxanthosine has been shown to inhibit the replication of DNA by forming a covalent bond with the deoxyribose sugar moiety of DNA. This modification prevents the polymerization of DNA, thereby inhibiting viral replication.Fórmula:C32H31N3O7Pureza:Min. 95%Peso molecular:569.6 g/mol3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine
CAS:3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine is a novel nucleoside phosphoramidite. The 3'-azido group can be used to protect the 5' hydroxyl group during phosphitylation, which is essential for the synthesis of modified nucleosides. The 2',3'-dideoxy configuration ensures that the sugar moiety is not cleaved from the base during polymerization, and that no undesired side reactions occur during purification. This product has been shown to have antiviral and anticancer activity in vitro.
Fórmula:C20H32N8O4SiPureza:Min. 95%Peso molecular:476.61 g/mol2'-Deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite
The 2'-deoxy-N2-isobutyryl-5'-O-levulinoylguanosine 3'-CE phosphoramidite is a high quality and novel nucleoside. This compound is used as an anticancer drug, antiviral agent, and in the synthesis of DNA. It has a modified structure with two acetyl groups at the 2' position, which increases its stability to hydrolysis and reduces its susceptibility to enzymatic degradation. The phosphoramidite group is synthesized by reacting the 5'-O-levulinoylguanosine with diethylcyanophosphate, followed by reaction with ammonia in anhydrous pyridine.Fórmula:C28H42N7O8PPureza:Min. 95%Peso molecular:635.65 g/mol2'-O-tert-Butyldimethylsilyl-3'-deoxy-5-methyluridine
CAS:2'-O-tert-Butyldimethylsilyl-3'-deoxy-5-methyluridine (2'-O-TBDMS-5'-dMU) is a synthetic nucleoside that is an antiviral agent. It has been shown to be an activator of DNA polymerase, which may be due to its ability to bind to the enzyme's catalytic site and inhibit the enzyme's activity. 2'-O-TBDMS-5'-dMU also has high purity and can be used in the synthesis of modified nucleosides, phosphoramidites, diphosphates, and ribonucleosides. 2'-O-TBDMS-5'-dMU is a white powder with a melting point of about 221°C. It is soluble in water and alcohols and insoluble in acetone or ether.Fórmula:C16H28N2O5SiPureza:Min. 95%Peso molecular:356.49 g/molN6-Benzoyl-9-(a-D-mannopyranosyl)adenine
N6-Benzoyl-9-(a-D-mannopyranosyl)adenine is a novel, synthetic nucleoside analog. It is an antiviral drug that inhibits viral replication by replacing the natural substrate in DNA synthesis. N6-Benzoyl-9-(a-D-mannopyranosyl)adenine has been shown to be effective against human leukemia cells and to have anticancer properties. This drug also stimulates the immune system by triggering the production of antibodies and other immunoglobulins.Fórmula:C18H19N5O6Pureza:Min. 95%Cor e Forma:PowderPeso molecular:401.37 g/mol3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine
CAS:3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine is an antitumor agent that belongs to the class of heterocyclic ring. It is a pyridinium salt with a benzoic acid residue at position 3 and 5'. The heterocyclic ring is derived from alkylene, which has two double bonds in the chain. This compound has low toxicity and can be synthesized from chloroform, fluorouridine, and pyridine. 3',5'-Di-O-acetyl-2'-deoxy-5-fluorouridine inhibits growth of cancer cells by binding to ribosomes and preventing RNA synthesis. It also acts as an alkylating agent that binds to DNA, leading to crosslinking between strands of DNA. This leads to cell death by apoptosis or necrosis due to interference with DNA replication.Fórmula:C13H15FN2O7Pureza:Min. 95%Peso molecular:330.27 g/mol3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine
3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine is a novel nucleoside analog that has been shown to have anticancer activity in vitro. The compound is a monophosphate, which is synthesized from 2'-deoxyuridine and benzoyl chloride. 3',5'-Di-O-benzoyl-2'-deoxy-2'-fluorouridine was found to have antiviral activity against herpes simplex virus type 1 (HSV1) and cytomegalovirus (CMV). It also inhibited the production of HIV in human lymphocytes. This nucleoside analog can be activated by phosphorylation at the 5' position to form a diphosphate, which inhibits DNA synthesis by incorporating into the growing DNA chain and preventing the movement of RNA polymerase along the template strand.Fórmula:C23H19FN2O7Pureza:Min. 95%Peso molecular:454.42 g/molTert-Butyl 2-Phenyl-4-(P-Tolylsulfonyloxy)-7,8-Dihydropyrido[4,3-D]Pyrimidine-6(5H)-Carboxylate
CAS:Tert-Butyl 2-Phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is an antiviral agent that inhibits the replication of DNA and RNA. It is a phosphoramidate nucleoside analog and a novel compound that has been modified to improve its stability. Tert-butyl 2-phenyl-4-(P-tolylsulfonyloxy)-7,8-dihydropyrido[4,3-D]pyrimidine-6(5H)-carboxylate is currently being investigated for use as a drug to treat HIV/AIDS. This compound has been shown to inhibit HIV protease by binding to the active site of the enzyme and preventing it from cutting the polypeptide chain into smaller pieces. Tert butyl 2 phenyl 4Fórmula:C25H27N3O5SPureza:Min. 95%Peso molecular:481.57 g/mol5-Methylcytidine
CAS:5-Methylcytidine is a methyltransferase enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine to 5-methylcytosine. This reaction is essential for DNA replication and repair. 5-Methylcytidine has been shown to be an important factor in the regulation of mitochondrial functions, as well as other cellular processes such as protein synthesis, nuclear DNA replication, and tumor suppression. It also has been shown to inhibit the replication of murine sarcoma virus and Toll-like receptor. 5-Methylcytidine can be used in chemotherapy treatment against mouse tumors and murine sarcoma virus by preventing viral RNA synthesis with monoclonal antibodies.Fórmula:C10H15N3O5Peso molecular:257.24 g/molRef: 3D-W-201877
-Unit-ggA consultar25gA consultar50gA consultar100gA consultar250gA consultar500gA consultar2'-TFA-NH-dA
CAS:2'-TFA-NH-dA is a monophosphate nucleotide. It is a novel and modified ribonucleoside that can be used as an activator to promote the synthesis of diphosphate, deoxyribonucleosides, and phosphoramidites. 2'-TFA-NH-dA has been shown to have anticancer properties in vitro and antiviral properties in vivo. This compound is synthesized from 2'-deoxyadenosine 5'-phosphate (2'-DAP), which is obtained from the amino acid ATP.Fórmula:C12H13F3N6O4Pureza:Min. 95%Peso molecular:362.26 g/mol5-O-DMT-thymidine 3'-H phosphonate triethylammonium
5-O-DMT-thymidine 3'-H phosphonate triethylammonium is a novel nucleoside analogue with anticancer activity. The monophosphate form of 5-O-DMT-thymidine 3'-H phosphonate triethylammonium is an activator of DNA, RNA, and protein synthesis in vitro. 5-O-DMT-thymidine 3'-H phosphonate triethylammonium has been shown to be active against herpes simplex virus type 1 and 2 and HIV type 1 in vitro.
Fórmula:C37H48N3O9PPureza:Min. 97 Area-%Cor e Forma:White/Off-White SolidPeso molecular:709.77 g/mol
![6-[(4-Nitrobenzyl)thio]-9-(b-D-ribofuranosyl)purine-5'-monophosphate disodium salt](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNN07313.webp&w=3840&q=75)
![Tert-Butyl 2-Phenyl-4-(P-Tolylsulfonyloxy)-7,8-Dihydropyrido[4,3-D]Pyrimidine-6(5H)-Carboxylate](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F3D%2Fthumb-webp%2FNB57393.webp&w=3840&q=75)
