Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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Adenosine 5'-triphosphate potassium salt
CAS:Adenosine 5'-triphosphate potassium salt is a membrane potential-sensitive fluorescent probe. It has been used to measure the intensity of light exposure and the depolarising effects of activation in sarcoplasmic reticulum vesicles. Adenosine 5'-triphosphate potassium salt has also been used to measure the activity of cyclic nucleotide phosphodiesterases, which are enzymes that regulate the breakdown of cAMP and cGMP. The fluorescence of adenosine 5'-triphosphate potassium salt increases with increased concentrations of cyclic nucleotide phosphodiesterase, indicating that it is an effective indicator for measuring these types of enzymes in biological assays.
Fórmula:C10H14K2N5O13P3Pureza:Min. 95%Peso molecular:583.36 g/molUridine 5'-O-(1-thiotriphosphate) lithium salt - 100mM aqueous solution
CAS:Mixture of Rp and Sp isomers.Fórmula:C9H15N2O14P3SPureza:Min. 95%Peso molecular:500.21 g/mol2'-Deoxyguanosine-5'-diphosphate disodium salt
CAS:2'-Deoxyguanosine-5'-diphosphate disodium salt is a marine metabolite that is used as a chemotactic agent for bacteria. It functions by stimulating motility and chemotaxis in marine bacteria. This metabolite is derived from the sulfur oxidation pathway and it has been shown to have genetic regulatory functions in the symbiosis of roseobacters. 2'-Deoxyguanosine-5'-diphosphate disodium salt interacts with the enteric bacteria clade, which may be due to its ability to cycle between sulfur and oxygen environments.Fórmula:C10H13N5O10P2·2NaPureza:Min. 95%Cor e Forma:White PowderPeso molecular:471.16 g/mol5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt
5-Aza-2'-deoxycytidine 5'-triphosphate sodium salt is an antiviral drug, which is a synthetic nucleoside analogue of cytidine. It inhibits the synthesis of viral DNA by competing with deoxycytidine triphosphate for incorporation into nascent DNA chains. This antiviral agent has been shown to be effective against HSV-1 and HIV-1 in vitro.Pureza:Min. 95%2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole
CAS:2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside with anticancer activity. It is an activator of phosphoramidite synthesis and has been shown to be an antiviral agent against herpes simplex virus type 1 (HSV-1). 2-Deoxy-1-(5'-O-DMT-b-D-ribofuranosyl)-5-nitroindole is a nucleoside that can be used for the synthesis of DNA or RNA. This product is offered in high purity, diphosphate form, at a monophosphate level.
Fórmula:C34H32N2O7Pureza:Min. 95%Peso molecular:580.63 g/molN2-Carbamoylthreonyl-2'-deoxyguanosine
N2-Carbamoylthreonyl-2'-deoxyguanosine is a phosphoramidite monophosphate that is used in the synthesis of DNA. It has antiviral and anticancer properties. N2-Carbamoylthreonyl-2'-deoxyguanosine is synthesized by modifying the nucleoside thymidine, which contains a 2'-deoxyribose sugar and an amino sugar, with carbamate linkages at the 2' position. This modification stabilizes the sugar moiety, preventing it from undergoing hydrolysis to form ribose and deoxyribose. The stability of the modified nucleoside allows for increased solubility in aqueous solution and increased resistance to degradation by nucleases. N2-Carbamoylthreonyl-2'-deoxyguanosine also has high purity and quality as well as novel modifications not found in other DNA building blocksPureza:Min. 95%N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine
CAS:N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is a novel modified nucleoside that is an activator of ribonucleosides. It has antiviral and anticancer activities, in addition to its potential as a DNA polymerase inhibitor. N4-Acetyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine is chemically synthesized with high purity and can be used for the synthesis of phosphoramidites for DNA synthesis. This compound also has the CAS number 12105885 3 and can be found in monophosphate form.Fórmula:C38H47N3O8SiPureza:Min. 95%Cor e Forma:PowderPeso molecular:701.88 g/mol2'-Deoxy-5-fluorocytidine 5'-monophosphate
CAS:2'-Deoxy-5-fluorocytidine 5'-monophosphate is a nucleotide that is synthesized by the enzyme cytidine deaminase. It is used as a diagnostic agent in the detection of infectious diseases such as HIV, Mycobacterium tuberculosis, and cytomegalovirus (CMV). 2'-Deoxy-5-fluorocytidine 5'-monophosphate inhibits DNA synthesis by blocking the incorporation of deoxycytidylate into DNA. The compound is also an inhibitor of collagen synthesis in tissues and cells. Hydrogen bonds between this compound and its target enzymes are thought to be important for its inhibitory effects.
Fórmula:C9H13FN3O7PPureza:Min. 95%Peso molecular:325.19 g/mol4'-C-Azido-3'-deoxy-3'-fluorocytidine
CAS:4'-C-Azido-3'-deoxy-3'-fluorocytidine is an antiviral, anticancer, and nucleoside phosphoramidite. It is a novel modified nucleoside that has antiviral, anticancer, and DNA modifying properties. 4'-C-Azido-3'-deoxy-3'-fluorocytidine has been shown to be an activator of the polymerase chain reaction (PCR). This product has high purity with no detectable impurities. The CAS number for this compound is 1145869-46-0. This product is available in bulk quantities.
Fórmula:C9H11FN6O4Pureza:Min. 95%Peso molecular:286.22 g/mol2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt - 100mM aqueous solution
2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is a novel, synthetic nucleoside. It is a monophosphate and can be activated with adenosine triphosphate to form the diphosphate. 2'-Deoxy-2'-fluoroguanosine-5'-triphosphate sodium salt is also an antiviral agent that inhibits viral RNA synthesis. The anticancer activity of 2'-deoxy-2'-fluoroguanosine-5' triphosphate sodium salt has not been studied in detail.Fórmula:C10H15FN5O13P3·NaPureza:Min. 95%Peso molecular:548.16 g/molN4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite
CAS:N4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It has been synthesized and purified by using the latest technology. It is a monophosphate, which is used in the synthesis of DNA, RNA, and other nucleic acids. It can be used for anticancer research and as a pharmaceutical intermediate.Fórmula:C52H74N5O10PSiPureza:Min. 95%Cor e Forma:White/Off-White SolidPeso molecular:988.23 g/mol5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite
CAS:5'-O-DMTr-2'-O,4'-C-methyleneuridine 3'-CE-phosphoramidite is a novel nucleoside phosphoramidite. It is an activator of DNA polymerase for the synthesis of diphosphate analogues of ribonucleosides and deoxyribonucleosides. This compound has been used in the synthesis of antiviral and anticancer agents, as well as in research on the development of new antiviral drugs.Pureza:Min. 95%N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine
CAS:N-(2-Amino-3,8-dimethylimidazo[4,5-f]quinoxalin-5-yl) 2'-deoxyguanosine (NADG) is a monophosphate nucleoside analog that inhibits the human immunodeficiency virus (HIV). NADG inhibits HIV by binding to the viral enzyme reverse transcriptase and inhibiting its activity. NADG also has anticancer activity through inhibition of DNA synthesis and protein synthesis. This compound is a novel nucleoside analog that has not been previously described in the literature.Fórmula:C21H22N10O4Pureza:Min. 95%Peso molecular:478.46 g/mol1-(2-Deoxy-b-D-threo-pentofuranosyl)-5-fluorouracil
CAS:1-(2-Deoxy-b-D-threo-pentofuranosyl)-5-fluorouracil (1dTfu) is an anticancer drug that belongs to the group of anti-metabolites. It is used in the treatment of colon cancer, head and neck cancer, urinary bladder cancer, and prostate cancer. 1dTfu inhibits the production of tyrosinase and other growth factors, which may be due to its ability to bind to a receptor called factor receptor on the surface of cells. This binding inhibits DNA synthesis by inhibiting the enzyme DNA polymerase. 1dTfu also has been shown to inhibit collagen synthesis via an extracellular mechanism.Fórmula:C9H11FN2O5Pureza:Min. 95%Peso molecular:246.19 g/mol2'-Azido-N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine
2'-Azido-N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine is a novel nucleoside that can be activated with phosphoramidite and used to synthesize a variety of modified nucleosides. It has been shown to have anticancer and antiviral activities, as well as the ability to inhibit the replication of RNA viruses. 2'-Azido-N6-benzoyl-2'-deoxy-5'-O-DMT-adenosine is also useful in the synthesis of monophosphate nucleotides, which are important for DNA synthesis. This product is available in high purity and quality and is CAS No.Pureza:Min. 95%2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine 3'-CE phosphoramidite
2'-Deoxy-5'-O-DMT-N2-isobutyryl-a-guanosine 3'-CE phosphoramidite is a novel, high quality nucleoside that is synthesized by the reaction of 5'-O-DMT-2'-deoxyguanosine with isobutyryl chloride. It has antiviral and anticancer properties and has been shown to be an activator of RNA polymerase. CAS number: 89879-16-1Fórmula:C44H54N7O8PPureza:Min. 95%Peso molecular:839.94 g/mol4-Amino-6-chloropyrimidine-5-carbaldehyde
CAS:4-Amino-6-chloropyrimidine-5-carbaldehyde is a reactive molecule that is used in the synthesis of macrocyclic aldehydes. It is prepared by the oxidation of anilines with oxalyl chloride in the presence of hydrochloric acid and amines. 4-Amino-6-chloropyrimidine-5-carbaldehyde reacts with hydrazine to form diamines, which are used as building blocks for pharmaceuticals. This molecule has been shown to have anticancer properties, by inhibiting DNA replication and cell growth through its ability to inhibit protein synthesis.Fórmula:C5H4ClN3OPureza:Min. 95%Peso molecular:157.56 g/mol5-Ethynyl-1-(b-D-ribofuranosyl)-imidazo-4-carbonitrile
CAS:5-Ethynyl-1-(b-D-ribofuranosyl)-imidazo-4-carbonitrile is a novel, modified ribonucleoside monophosphate that has antiviral, anticancer, and antiretroviral properties. It was originally synthesized as an activator of the DNA polymerase and is capable of stimulating the synthesis of RNA from DNA templates. It has been shown to inhibit the growth of cancer cells in vitro and in vivo. 5-Ethynyl-1-(b-D-ribofuranosyl)-imidazo-4-carbonitrile is also a phosphoramidite nucleotide analog that can be incorporated into DNA during DNA synthesis.Fórmula:C11H11N3O4Pureza:Min. 95%Peso molecular:249.22 g/molS-(2-Hydroxy-5-nitrobenzoyl)-6-thioinosine
CAS:S-(2-Hydroxy-5-nitrobenzoyl)-6-thioinosine is a population of endogenous inotropic agents that are transported by the uptake system. It interacts with benzodiazepine receptor and has been shown to act as an agonist. The uptake system is responsible for the uptake of S-(2-hydroxy-5-nitrobenzoyl)-6-thioinosine, which then binds to the benzodiazepine receptor. This binding causes an increase in cAMP levels and subsequent relaxation of smooth muscle cells. S-(2-hydroxynitrobenzoyl)-6-thioinosine has been shown to be a transport inhibitor, which affects the uptake of other drugs such as benzodiazepines and antiepileptics. It also modulates responsiveness through interaction with the transport system.Fórmula:C17H17N5O7SPureza:Min. 95%Peso molecular:435.41 g/mol2-Amino-6-chloro-9-(3'-deoxy-3'-fluoro-b-D-ribofuranosyl)-9H-purine
CAS:2-Amino-6-chloro-9-(3'-deoxy-3'-fluoro-b-D-ribofuranosyl)-9H-purine is a novel, activator ribonucleoside phosphoramidite and monophosphate nucleoside. It is synthesized from 2,4,5,6,-tetraiodo-1H-[1]pyrrole and 6-chloropurine ribofuranose. The chemical name is 1-[2'-(deoxyribofuranosyl) (3', 3'', 5', 5'', 5'')-2'-(2,4,5,6 tetraiodophenyl)] -2-(3'-fluorobenzoyl) -4-(3'-triazolecarboxamide) -1H-[1]pyrrole 4,5 dione. CAS No. 1612192-05-8.Pureza:Min. 95%
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