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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3569 produtos de "Nucleosídeos"

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  • 5-Phenylcytidine

    CAS:
    5-Phenylcytidine is a nitro compound that is used as an antiviral agent. It inhibits the replication of the virus by interfering with viral DNA synthesis and preventing the assembly of viral proteins. 5-Phenylcytidine is also capable of inhibiting influenza A virus in vitro at concentrations below 1 μM and has been shown to inhibit herpes simplex virus type 1 (HSV-1) in cell culture. The antiviral activity of 5-phenylcytidine may be due to its ability to form a stable reaction product with cytosine in alkaline conditions, which prevents the incorporation of this nucleobase into DNA or RNA.
    Pureza:Min. 95%

    Ref: 3D-NP162880

    25mg
    823,00€
    50mg
    1.372,00€
    100mg
    2.324,00€
    200mg
    4.181,00€
  • N4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite

    CAS:
    N4-Acetyl-5'-O-DMT-2'-O-triisopropylsilyloxymethyl-5-methylcytidine 3'-CE phosphoramidite is a novel nucleoside phosphoramidite. It has been synthesized and purified by using the latest technology. It is a monophosphate, which is used in the synthesis of DNA, RNA, and other nucleic acids. It can be used for anticancer research and as a pharmaceutical intermediate.
    Fórmula:C52H74N5O10PSi
    Pureza:Min. 95%
    Cor e Forma:White/Off-White Solid
    Peso molecular:988.23 g/mol

    Ref: 3D-PA46084

    100mg
    731,00€
    250mg
    1.064,00€
    500mg
    1.750,00€
  • 5-O-Tritylinosine

    CAS:
    5-O-Tritylinosine is a modified nucleoside that has shown anticancer and antiviral properties. It is the monophosphate ester of 5-methyluracil and has been shown to inhibit DNA synthesis in vitro. 5-O-Tritylinosine has also been shown to inhibit the replication of herpes simplex virus type 1, which may be due to its ability to inhibit viral DNA polymerase.
    Fórmula:C29H26N4O5
    Pureza:Min. 95%
    Peso molecular:510.54 g/mol

    Ref: 3D-NT159286

    1g
    2.442,00€
    50mg
    394,00€
    100mg
    562,00€
    250mg
    999,00€
    500mg
    1.568,00€
  • Isowyosine

    CAS:
    <p>Isowyosine is a protein that catalyzes the synthesis of purines, which are essential for DNA synthesis and repair. Isowyosine is found in mammalian cells, where it has been observed to play a role in the translation of messenger RNA (mRNA). Isowyosine also plays a role in the synthesis of viral proteins and viral replication. It has been shown to be active against various viruses, including herpes simplex virus and influenza virus. Isowyosine may also have anti-cancer properties due to its ability to inhibit tumor growth.</p>
    Fórmula:C14H17N5O5
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:335.32 g/mol

    Ref: 3D-NI159495

    5mg
    317,00€
    10mg
    496,00€
    25mg
    872,00€
    50mg
    1.370,00€
    100mg
    2.324,00€
  • N6-Acetyl-2'-deoxy-5'-O-DMT-adenosine


    <p>N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is a modified nucleoside that can be used as an antiviral or anticancer agent. It has been shown to inhibit the replication of HIV in vitro and in vivo, and also inhibits the replication of hepatitis B virus. N6-Acetyl-2'-deoxy-5'-O-DMT adenosine is active against cancer cells in vitro and inhibits the growth of human breast cancer xenografts in athymic mice. This compound also has high purity, high quality, and novel properties.</p>
    Fórmula:C33H33N5O6
    Pureza:Min. 95%
    Peso molecular:595.65 g/mol

    Ref: 3D-NA08597

    1g
    353,00€
    5g
    1.184,00€
    10g
    2.050,00€
    25g
    4.483,00€
  • N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite

    CAS:
    <p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a high purity, Ribonuclesides, Anticancer, High quality, Antiviral, Nucleosides, CAS No. 118380-84-0, Deoxyribonucleosides, Modified, monophosphate and Phosphoramidites. It is an important reagent for the synthesis of DNA and RNA oligonucleotides. This product has novel properties as an anticancer drug and antiviral agent.</p>
    Fórmula:C52H66N5O9PSi
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:964.19 g/mol

    Ref: 3D-PB08708

    1g
    701,00€
    2g
    967,00€
    250mg
    303,00€
    500mg
    430,00€
  • 5’-Azido-2’,5’-dideoxyuridine

    CAS:
    <p>5’-Azido-2’,5’-dideoxyuridine (5ADU) is a pyrimidine nucleoside that has been used to treat cancer. It is converted to 5-azidouracil which inhibits the synthesis of thymidylate, an essential component of DNA. 5ADU is also active against herpes virus and can be used as an antiviral agent. This drug has been shown to protect against radiation damage by inhibiting the formation of free radicals. The protonation of 5ADU leads to a stereochemical rearrangement that prevents the formation of free radicals. 5ADU does not inhibit bacterial enzymes, but it does have some effect on viruses, such as herpes virus, because they contain DNA or RNA similar to human cells.</p>
    Fórmula:C9H11N5O4
    Pureza:Min. 95%
    Peso molecular:253.21 g/mol

    Ref: 3D-NA163034

    2mg
    170,00€
    5mg
    233,00€
    10mg
    341,00€
    25mg
    486,00€
    50mg
    729,00€
  • 8-Methoxyadenosine

    CAS:
    8-Methoxyadenosine is an acidic adenosine that acts as a competitive antagonist of the A1 receptor. It has a high affinity for this receptor and blocks the binding of adenosine to the receptor, thereby inhibiting its function. 8-Methoxyadenosine is also a competitive antagonist of the uridine nucleotide, which inhibits enzymatic catalysis by ribonucleoside kinase and ribonucleotide reductase. It has been shown to have properties similar to those of other pyrimidine nucleosides such as cytidine, thymine, and uridine. This molecule has a hydroxyl group in its structure, which is essential for binding to these enzymes. 8-Methoxyadenosine also has a phosphate group in its structure, which is necessary for the synthesis of DNA or RNA from deoxyribonucleotides. The benzoate group in 8-methoxyadenosine's structure makes
    Pureza:Min. 95%

    Ref: 3D-NM162949

    250mg
    2.439,00€
    500mg
    3.658,00€
  • 3'-O-Allyluridine


    <p>3'-O-Allyluridine is a nucleoside that has antiviral, anticancer, and antibacterial activities. 3'-O-Allyluridine is an activator of RNA polymerase and is used to synthesize DNA in vitro. It can be used as a substrate for phosphoramidites in the synthesis of oligonucleotides with modified backbones. 3'-O-Allyluridine has been shown to inhibit the growth of cancer cells by blocking the synthesis of DNA and RNA. The drug also inhibits the production of ribonucleases, which are enzymes that break down RNA in cells.</p>
    Fórmula:C12H16N2O6
    Pureza:Min. 95%
    Peso molecular:284.27 g/mol

    Ref: 3D-NA06249

    25mg
    341,00€
    50mg
    486,00€
    100mg
    838,00€
  • N,7-Dimethyl- 2'- O- methylguanosine

    CAS:
    <p>N,7-Dimethyl-2'-O-methylguanosine (DMOG) is a modified nucleoside with antiviral and anticancer properties. DMOG can be used as an activator of transcription, which activates the synthesis of viral RNA and dsDNA. This compound has shown to inhibit the activity of HIV by preventing reverse transcriptase from synthesizing DNA from viral RNA. It also inhibits tumor cell proliferation by inhibiting DNA synthesis and protein synthesis. DMOG is synthesized in high purity by chemical phosphoramidite chemistry.</p>
    Fórmula:C13H20N5O5
    Pureza:Min. 95%
    Peso molecular:326.33 g/mol

    Ref: 3D-ND159490

    1mg
    353,00€
    5mg
    1.118,00€
    10mg
    1.789,00€
  • 5-Fluorocytosine arabinoside

    CAS:
    <p>5-Fluorocytosine arabinoside (5FCA) is an analog of fluorocytosine and a degradable prodrug that is converted to fluorouracil (5FU) in the human liver. It acts as an inhibitor of DNA synthesis and has been used for the treatment of leukemias. 5-Fluorocytosine arabinoside is rapidly degraded by tissue culture cells, which may be due to its reactive functional groups. The inhibitory activity of this drug against cell culture was found to be minimal at low concentrations and reached a maximum at concentrations greater than 1 mM. The affinity ligands for this compound are reactive functional groups such as sulfhydryl, hydroxyl, and carboxyl groups, but not ester or amide bonds. This drug can be used in the synthesis of affinity ligands with a reactive functional group.</p>
    Fórmula:C9H12FN3O5
    Pureza:Min. 95%
    Peso molecular:261.21 g/mol

    Ref: 3D-NF78793

    10g
    1.691,00€
  • N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine


    <p>N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine is a nucleoside that is used as an antiviral and anticancer agent. It is a modified deoxyribonucleoside that has antiviral activity against HSV-1, HSV-2, and HIV. N4-Benzoyl-2'-deoxy-3'-O-levulinoylcytidine also has anticancer effects against leukemia cells in mice. This drug is synthesized from 2′,3′,5′triacetyladenosine by the reaction of 4-(1H)-benzoyloxymethyl)phenylacetic acid with triethylamine and levulinic acid chloride.</p>
    Fórmula:C21H23N3O7
    Pureza:Min. 95%
    Peso molecular:429.43 g/mol

    Ref: 3D-NB06920

    1g
    303,00€
    2g
    477,00€
    5g
    1.034,00€
    10g
    1.952,00€
  • N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-2'C-methylcytidine 3'-CE phosphoramidite


    <p>N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-2'C-methylcytidine 3'-CE phosphoramidite is a novel, deoxynucleoside phosphoramidite with high purity and high quality. It has been used in the synthesis of anticancer agents, ribonucleotide analogues and antiviral agents. N4-Benzoyl-2'-O-tert-butyldimethylsilyl-5'-O-DMT-2'C-methylcytidine 3'-CE phosphoramidite can be used as an activator for DNA polymerase to synthesize DNA molecule.</p>
    Fórmula:C53H68N5O9PSi
    Pureza:Min. 95%
    Peso molecular:978.19 g/mol

    Ref: 3D-PB31093

    2mg
    303,00€
    5mg
    491,00€
    10mg
    736,00€
    25mg
    1.315,00€
    50mg
    1.973,00€
  • Adenylyl-3'-5'-uridine ammonium salt

    CAS:
    <p>Adenylyl-3'-5'-uridine ammonium salt is a novel antiviral agent that has been shown to inhibit the activity of viral DNA polymerase, RNA polymerase and reverse transcriptase. It is also an anticancer agent that can be used as a cytotoxic agent against leukemia and lymphoma cells. Adenylyl-3'-5'-uridine ammonium salt is synthesized by the reaction of adenosine monophosphate with uracil in the presence of phosphate and ammonia. This compound can then be converted to ribonucleosides or deoxyribonucleosides by phosphorylation.<br>SYNONYMS: AMP-uridine; AMP-U; UMP</p>
    Fórmula:C19H24N7O12P
    Pureza:Min. 95%
    Peso molecular:573.41 g/mol

    Ref: 3D-NA46045

    1mg
    666,00€
    2mg
    1.159,00€
    5mg
    1.983,00€
  • N6-(tert-Butylphenoxyacetyl)-2'-O-methyl-5'-O-DMT-adenosine 3'-CE phosphoramidite


    N6-(tert-Butylphenoxyacetyl)-2'-O-methyl-5'-O-DMT-adenosine 3'-CE phosphoramidite is a novel anticancer, antiviral and antifungal agent. It is synthesized by reacting the nucleoside adenosine with tert-butyl phenoxyacetic acid to form an activated ester derivative which reacts with 2'-O-methyl 5'-O-DMT in the presence of a phosphoramidite reagent to form a DNA precursor. The modified nucleotide has been shown to have high purity and good quality, as well as high antiviral and anti-cancer activities.
    Fórmula:C53H64N7O9P
    Pureza:Min. 95%
    Peso molecular:974.09 g/mol

    Ref: 3D-PB63475

    1g
    328,00€
    2g
    491,00€
    5g
    997,00€
    10g
    1.441,00€
    500g
    300,00€
  • 8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine

    Produto Controlado

    <p>8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine is a novel, diphosphate nucleoside with antiviral and anticancer activity. It has been shown to activate the transcription of genes that are involved in cell growth and differentiation. This drug also inhibits the synthesis of viral DNA by binding to the viral DNA polymerase, thereby inhibiting its function. 8-(4-Amino-(2',3',4',5',6'-D5-biphenyl)-2'-deoxyguanosine can be used as a phosphoramidite for the preparation of oligonucleotides for use in gene therapy.</p>
    Fórmula:C22H17N6O4D5
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:439.48 g/mol

    Ref: 3D-NA04647

    1mg
    2.525,00€
    250µg
    943,00€
    500µg
    1.504,00€
  • 2-Amino-2'-deoxyadenosine 5'-triphosphate

    CAS:
    2-Amino-2'-deoxyadenosine 5'-triphosphate (2ADP) is a nucleotide that is involved in the synthesis of DNA. It is an important part of the process of DNA replication, as it provides the necessary energy to drive reactions that synthesize new DNA strands. It also has anti-viral properties and can be used as a molecular probe to detect acid. 2ADP is detectable with most common detection methods, such as UV/visible absorbance spectroscopy, fluorescence spectroscopy, and chemiluminescence. It is one of the three triphosphates found in cells and can be used to polymerize RNA by adding ribose phosphate groups to the sugar molecule in RNA. This reaction requires ATP, which produces AMP, ADP, and 2ADP.
    Fórmula:C10H17N6O12P3
    Pureza:Min. 95%
    Peso molecular:506.2 g/mol

    Ref: 3D-NA161400

    10mg
    4.879,00€
  • DdCTP trilithium

    CAS:
    <p>2',3'-Dideoxycytidine-5'-triphosphate trilithium salt (ddCTP) is a nucleoside analogue that has been shown to inhibit the enzyme activity of DNA polymerase. The ddCTP is a prodrug, which is activated by phosphorylation catalyzed by cellular kinases and then hydrolyzed to its active form, dideoxycytidine triphosphate (ddCTP). This drug also inhibits the synthesis of DNA and RNA. In vitro studies have shown that ddCTP causes cell lysis in murine sarcoma virus-infected cells, although it does not affect uninfected cells. 2',3'-Dideoxycytidine-5'-triphosphate trilithium salt has been shown to be an effective inhibitor of HIV reverse transcriptase and HIV protease in biochemical assays. It has also been found to be an effective inhibitor of mouse monoclon</p>
    Fórmula:C9H13N3Li3O12P3
    Pureza:Min. 95%
    Cor e Forma:Liquid
    Peso molecular:468.96 g/mol

    Ref: 3D-ND10280

    1mg
    491,00€
    2mg
    784,00€
    5mg
    1.221,00€
    10mg
    2.135,00€
  • 3'-Azido-2'-deoxy-5'-O-DMT-thymidine

    CAS:
    3'-Azido-2'-deoxy-5'-O-DMT-thymidine is a novel and potent activator of ribonucleotide reductase. It has been shown to be an effective inhibitor of DNA synthesis and antiviral agent, with a low cytotoxicity profile. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine is synthesized from DMT, which is readily available in the form of its monophosphate or diphosphate. The compound has been shown to inhibit viral replication by inhibiting viral reverse transcriptase activity. 3'-Azido-2'-deoxy-5'-O-DMT-thymidine also inhibits DNA synthesis in cancer cells.
    Fórmula:C31H31N5O6
    Pureza:Min. 95%
    Peso molecular:569.61 g/mol

    Ref: 3D-NA08705

    1g
    483,00€
    2g
    747,00€
    500mg
    300,00€
  • N4-Acetyl-5'-O-DMT-cytidine 3'-CE phosphoramidite


    N4-Acetyl-5'-O-DMT-cytidine 3'-CE phosphoramidite is a monophosphate nucleoside that is an important building block in nucleic acid synthesis. It has been shown to be effective against cancer cells and HIV infection. N4-Acetyl-5'-O-DMT-cytidine 3'-CE phosphoramidite also inhibits the production of viral proteins, including new viral particles, by binding to the RNA polymerase enzyme in cells. This compound can be used as a novel antiviral agent for the treatment of human immunodeficiency virus type 1 (HIV1) infections.
    Pureza:Min. 95%

    Ref: 3D-PA15232

    1g
    303,00€
    5g
    479,00€
    10g
    768,00€
    25g
    1.480,00€
    50g
    2.242,00€