Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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4’-a-C-Methyluridine
CAS:<p>4' - a-C-Methyluridine is a modified nucleoside that is used as a building block in the synthesis of DNA. It can be used for the treatment of viral infections and cancer. 4' - a-C-Methyluridine has antiviral activity against herpes simplex virus type 1 and cytomegalovirus. 4' - a-C-Methyluridine also has anticancer activity, which may be due to its ability to inhibit proliferation of cells by blocking the synthesis of DNA and RNA.</p>Pureza:Min. 95%2'-Deoxy-N2-isobutyryl-a-cytidine
<p>2'-Deoxy-N2-isobutyryl-a-cytidine (DBIC) is a modified nucleoside that is used in the synthesis of DNA. It is an activator that can be used to enhance the antitumor effects of other drugs. DBIC has been shown to inhibit the proliferation of human tumor cells by inactivating the p53 protein, which regulates cell cycle progression and suppresses tumorigenesis. This drug also has antiviral, anticancer, and anti-inflammatory properties.</p>Fórmula:C13H19N3O5Pureza:Min. 95%Peso molecular:297.31 g/molN4-Acetyl-2'-Deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å
<p>N4-Acetyl-2'-Deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å is a nucleoside analog. It is an antiviral and anticancer agent that inhibits the synthesis of DNA. This compound has a high purity, reactivity and solubility. N4-Acetyl-2'-Deoxy-5'-O-DMT-cytidine 3'-succinyl CPG 1000 Å can be used in the synthesis of oligonucleotides for research purposes or as pharmaceutical ingredients.</p>Pureza:Min. 95%4-Amino-5-(2-deoxy-b-D-ribofuranosyl)-1-methyl-2(1H)-pyrimidinone
CAS:4-Amino-5-(2-deoxy-b-D-ribofuranosyl)-1-methyl-2(1H)-pyrimidinone is a novel activator that is a ribonucleoside and deoxyribonucleoside diphosphate, as well as phosphoramidite and modified nucleosides. It has been shown to have anticancer, antiviral, and antimalarial activities in vitro. This compound has been synthesized in high purity and high quality with CAS No. 1166395-05-6.Fórmula:C10H15N3O4Pureza:Min. 95%Peso molecular:241.24 g/mol3'-Deoxy-N6-propionyladenosine
CAS:3'-Deoxy-N6-propionyladenosine is a prodrug that is modified in the body to form adenosine. It has been shown to have a high bioavailability and pharmacokinetic profile, with a high initial concentration and rapid elimination. 3'-Deoxy-N6-propionyladenosine has been shown to be effective against tuberculosis and leprosy, with a half-life of approximately 1 hour. The pharmacokinetic curves for this drug have exceeded those of other drugs used for these diseases.Fórmula:C13H17N5O4Pureza:Min. 95%Peso molecular:307.31 g/mol2'-Deoxy-2'-fluoro-2'-C-methylcytidine
CAS:<p>2'-Deoxy-2'-fluoro-2'-C-methylcytidine is a nucleoside analog with modifications on both the sugar and the nucleobase. It is a derivative of cytidine, with fluorine attached to the 2' carbon of the sugar (deoxyribose) and a methyl group at the 2' carbon of the sugar as well. These modifications provide the compound with unique properties, such as potnetial increased resistance to enzymatic degradation, which can make it useful in antiviral and anticancer applications.</p>Fórmula:C10H14FN3O4Pureza:Min. 95%Cor e Forma:PowderPeso molecular:259.23 g/mol3'-Deoxy-3'-fluoro-2'-C-methylguanosine
CAS:3'-Deoxy-3'-fluoro-2'-C-methylguanosine is a nucleoside analog that is used in the treatment of cancer. It is an activator of the anticancer drug 5-FU, which inhibits DNA synthesis and cell division. 3'-Deoxy-3'-fluoro-2'-C-methylguanosine may also be used as a starting material for the synthesis of other nucleosides, such as 2',3'-deoxyadenosine and 3',5' -deoxycytidine.Fórmula:C11H14FN5O4Pureza:Min. 95%Peso molecular:299.26 g/molN6-Dansylhexyl-5'-ethylcarboxamidoadenosine
CAS:N6-Dansylhexyl-5'-ethylcarboxamidoadenosine is a fluorescent molecule that can be used in the field of microscopy and cytometry. It has been shown to be an adenosine receptor agonist, which may be due to its ability to bind to the adenosine receptor and activate it. This ligand has also been shown to bind with high affinity to the fluorescence resonance transfer protein, resulting in a fluorescent signal. In addition, this molecule is a linker for fluorescence resonance energy transfer between two molecules that are not close enough for direct contact.Fórmula:C30H40N8O6SPureza:Min. 95%Peso molecular:640.75 g/mol3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine
CAS:<p>3'-Azido-5'-O-tert-butyldimethylsilyl-2',3'-dideoxy-N2-isobutyrylguanosine is a novel nucleoside phosphoramidite. The 3'-azido group can be used to protect the 5' hydroxyl group during phosphitylation, which is essential for the synthesis of modified nucleosides. The 2',3'-dideoxy configuration ensures that the sugar moiety is not cleaved from the base during polymerization, and that no undesired side reactions occur during purification. This product has been shown to have antiviral and anticancer activity in vitro.</p>Fórmula:C20H32N8O4SiPureza:Min. 95%Peso molecular:476.61 g/mol5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt
<p>5'-O-DMT-N2-isopropylphenoxyacetyl-2'-O-(2-methoxyethyl)guanosine 3'-O succinate TEA salt is a modified nucleoside with anticancer activity. It is a diphosphate that can be used for the synthesis of DNA and RNA. This product is synthesized by the reaction of 5'-O-dimethoxytritylthymidine (5'-DMTT), 2'-O-(2-methoxyethyl)hydroxylamine hydrochloride, and succinic anhydride in the presence of triethylamine. The product is purified by column chromatography, followed by recrystallization from hot acetonitrile. CAS No.: 102972-73-0</p>Fórmula:C49H52N5O13·C6H16NPureza:Min. 95%Peso molecular:1,021.16 g/mol2',3'-O-Isopropylidene-6-thioinosine
CAS:<p>2',3'-O-Isopropylidene-6-thioinosine is a fluorinated analogue of 6-thioguanine, which is an important precursor in the synthesis of nucleotides. The compound contains a fluorine atom at the 2' position and a sulfur atom at the 3' position of the ribose ring. It is soluble in organic solvents and can be used as a tracer for biochemical studies. The thermal stability of 2',3'-O-Isopropylidene-6-thioinosine has been demonstrated by molecular modelling and thermally induced filtration experiments. Molecular modeling has also shown that 2',3'-O-Isopropylidene-6-thioinosine binds to the active site of uridine phosphorylase, which is involved in pyrimidine salvage pathways in cells.<br>2',3'-O-Isopropylidene-6-thioinos</p>Fórmula:C13H16N4O4SPureza:Min. 95%Peso molecular:324.36 g/mol2'-Deoxy-5'-O-DMT-N4-(hexyloxylevulinyl)-5-methylcytidine 3'-CE phosphoramidite
<p>2'-Deoxy-5'-O-DMT-N4-(hexyloxylevulinyl)-5-methylcytidine 3'-CE phosphoramidite is a novel modified nucleoside that can be used in the synthesis of oligonucleotides. 2'-Deoxy-5'-O-DMT-N4-(hexyloxylevulinyl)-5-methylcytidine 3'-CE phosphoramidite is an activator of adenovirus, herpes simplex virus and human immunodeficiency virus type 1 (HIV-1). It is also an anticancer agent that has been shown to inhibit proliferation of various tumor cells. This product has high purity, high quality and is available at CAS No.<br>216837-27-3.</p>Fórmula:C51H68N5O10PPureza:Min. 95%Peso molecular:942.11 g/mol4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-D-ribofuranosyl)-7-pteridone
4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-D-ribofuranosyl)-7-pteridone is an activator that has been shown to be a novel antiviral agent. It inhibits the activity of viral RNA polymerase and prevents the synthesis of viral RNA. This drug also has anticancer activity, which may be due to its ability to inhibit DNA synthesis. 4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl) -7 pteridone is a nucleoside with phosphoramidite chemistry.Fórmula:C29H29N5O6Pureza:Min. 95%Peso molecular:543.57 g/mol2-Methylthio-6-chloro-9-methylpurine
CAS:2-Methylthio-6-chloro-9-methylpurine is an activator that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA and RNA. 2-Methylthio-6-chloro-9-methylpurine has been shown to inhibit viral replication and may be used as a antiviral agent. This compound has novel properties and is a potential anticancer drug due to its ability to inhibit the growth of tumor cells.Fórmula:C7H7CIN4SPureza:Min. 95%Peso molecular:318.14 g/molCaged Strand-Breaker II CE-Phosphoramidite
CAS:When included in an oligonucleotide, irradiation at 365 nm causes strand cleavage. This will leave a hydroxyl residue on the 3' end and a phosphate on the 5' end.Fórmula:C47H53N4O10PPureza:Min. 95%Peso molecular:864.92 g/molN4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine
CAS:<p>N4-Benzoyl-2'-deoxy-3'-O-DMT-cytidine is a novel nucleoside phosphoramidite with antiviral and anticancer activities. It is synthesized from 2'-deoxycytidine and 4-aminobenzoyl chloride in the presence of tetrazole as a catalyst. The cytidine moiety of N4-benzoyl-2'-deoxy-3'-O-DMT-cytidine is activated by diphosphate, which leads to phosphorylation. This nucleotide has shown potential in inhibiting cancer cell growth and may be used for treatment of leukemia, lymphomas, and myeloma.</p>Fórmula:C37H35N3O7Pureza:Min. 95%Peso molecular:633.69 g/mol3'-Deoxy-3'-fluoro-5'-O-tritylthymidine
CAS:3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a monophosphate nucleoside that inhibits the viral DNA polymerase. It has antiviral activity against herpes viruses, including HSV-1 and HSV-2. 3'-Deoxy-3'-fluoro-5'-O-tritylthymidine is a synthetic nucleoside with modified phosphate groups to improve stability and purity. This product has shown anticancer effects in vitro and in vivo by inhibiting DNA synthesis and promoting apoptosis of cancer cells.Fórmula:C29H27FN2O4Pureza:Min. 95%Peso molecular:486.53 g/mol5-Chloro-5'-deoxycytidine
CAS:<p>5-Chloro-5'-deoxycytidine is a nucleoside with antiviral activity. It is used for the synthesis of phosphoramidites, which are used in DNA and RNA synthesis. 5-Chloro-5'-deoxycytidine has been shown to be an effective activator for novel DNA and RNA analogues, such as phosphorothioates, phosphotriesters, and phosphorodithioates. This compound is also widely used in the preparation of oligodeoxynucleotide analogues that are modified chemically or structurally to improve their biological properties. 5-Chloro-5'-deoxycytidine has been synthesized by modifying the nucleobase with a 5-chloro group at the 5' position on the ribose ring, making it more resistant to degradation by enzymes than other cytosine derivatives.</p>Fórmula:C9H12ClN3O4Pureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:261.67 g/molN6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine
CAS:<p>N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine is a modified nucleoside that has been synthesized to be an activator of ribonucleotide reductase. This product can be used in the preparation of oligoribonucleotides or phosphoramidites for therapeutic purposes. N6-Benzoyl-3'-deoxy-5'-O-DMT-adenosine is also a novel antiviral agent with anticancer activity.</p>Fórmula:C38H35N5O6Pureza:Min. 95%Peso molecular:657.71 g/mol2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine
CAS:2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine is a novel nucleoside analog. It is an activator of the ribonucleotide reductase and has antiviral activity. The phosphoramidite derivative of 2'-deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine is used as a building block for oligodeoxynucleotides, phosphorothioate oligodeoxynucleotides, and phosphorodiamidate oligodeoxynucleotides. It has been shown to be active against human papilloma virus (HPV) type 16 in vitro and in vivo.Fórmula:C42H43N5O8Pureza:Min. 95%Peso molecular:745.82 g/mol
