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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3569 produtos de "Nucleosídeos"

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  • Uridylyl-3'-5'-adenosine ammonium salt


    <p>Uridylyl-3'-5'-adenosine ammonium salt is a novel antiviral agent that is used to treat hepatitis B. It is an analogue of nucleoside monophosphate, which is activated by adenylyltransferase, and inhibits viral DNA synthesis. Uridylyl-3'-5'-adenosine ammonium salt has been shown to inhibit the growth of cancer cells in vitro and in vivo. This drug also has anticancer activity against various types of cancer cell lines.</p>
    Fórmula:C19H27N8O12P
    Pureza:Min. 95%
    Peso molecular:590.44 g/mol

    Ref: 3D-NU46047

    1mg
    666,00€
    2mg
    1.159,00€
    5mg
    1.983,00€
  • 3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine


    <p>3'-Azido-2',3'-dideoxy-5'-O-DMT-5-methylcytidine (Zidovudine) is a nucleoside analog that inhibits the replication of human immunodeficiency virus type 1. It is phosphorylated by cellular enzymes to form the active triphosphate form, which incorporates into viral DNA and causes chain termination. Zidovudine has been used in the treatment of HIV infection and AIDS. This drug also has antiviral activity against other retroviruses such as HIV type 2 and measles virus, as well as some DNA viruses, such as herpes simplex type 1. Zidovudine may be useful for the treatment of cancer, particularly Kaposi's sarcoma.</p>
    Pureza:Min. 95%

    Ref: 3D-NA145616

    100mg
    303,00€
    250mg
    580,00€
    500mg
    1.003,00€
  • 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite)

    CAS:
    <p>Please enquire for more information about 2'-Deoxyxanthosine ce-phosphoramidite (dx ce-phosphoramidite) including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Fórmula:C56H61N8O12P
    Pureza:Min. 95%
    Peso molecular:1,069.1 g/mol

    Ref: 3D-SLA05043

    250mg
    954,00€
    500mg
    1.248,00€
  • 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine

    CAS:
    <p>3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is a novel antiviral agent that has been synthesized as a high quality, high purity monophosphate. It is a modified nucleoside that is used to synthesize phosphoramidites. It has antiviral activity against herpes simplex virus type 1 and 2, and cytomegalovirus. 3',5'-Di-O-acetyl-5-bromo-2'-deoxy-2'-fluorouridine is also an inhibitor of the DNA polymerase enzyme and inhibits the synthesis of viral DNA in infected cells. This drug can be used for the treatment of infections caused by these viruses.</p>
    Fórmula:C13H14BrFN2O7
    Pureza:Min. 95%
    Peso molecular:409.16 g/mol

    Ref: 3D-ND15626

    100mg
    303,00€
    250mg
    454,00€
  • 2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde

    CAS:
    <p>2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a Ribonucleside, Deoxyribonucleoside, Activator, Antiviral, Synthetic and Modified DNA Nucleoside. It has been shown to inhibit viral replication in vitro by interfering with the formation of the viral diphosphate. 2-Methylsulfanyl-4-phenylamino-pyrimidine-5-carbaldehyde is a ribonucleotide that is synthesized from commercially available starting materials. This compound has shown to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment of AIDS.<br>2-Methylsulfanyl-4-phenylamino pyrimidine 5 carbaldehyde (2MSAP) was found to be active against HIV type 1 virus in vitro and has been proposed as a potential antiviral agent for the treatment of</p>
    Fórmula:C12H11N3OS
    Pureza:Min. 95%
    Peso molecular:245.3 g/mol

    Ref: 3D-NM57378

    1g
    478,00€
    2g
    725,00€
    5g
    1.067,00€
    500mg
    300,00€
  • 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine

    CAS:
    <p>5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine is a nucleoside analog that is an activator of DNA polymerase. It has been shown to have anticancer activity in vitro and in vivo. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine was found to inhibit the proliferation of leukemia cells, human colon cancer cells, and human prostate cancer cells. This compound also inhibits viral replication by affecting the synthesis of viral DNA and RNA. 5'-O-DMT-5-[N-(2-(trifluoroacetamido)ethyl)-3-E-acrylamido]-2'-deoxyuridine may be used as a research tool for studying the mechanism of action of antiviral drugs such</p>
    Fórmula:C37H37F3N4O9
    Pureza:Min. 95%
    Peso molecular:738.74 g/mol

    Ref: 3D-ND08236

    1g
    1.120,00€
    100mg
    303,00€
    250mg
    413,00€
    500mg
    669,00€
  • 2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one

    CAS:
    <p>2-Amino-8-(2-deoxy-β-D-ribofuranosyl)-imidazo[1,2-α]-1,3,5-triazin-4(8H)-one is a modified nucleoside analog with the following structure: the core heterocyclic structure is a fused imidazole-triazine ring, there is a 2-amino group at position 2 of the imidazole ring and it has a 2-deoxy-β-D-ribofuranose sugar attached at the 8-position of the heterocyclic ring, making it structurally related to DNA nucleosides.</p>
    Fórmula:C10H13N5O4
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:267.24 g/mol

    Ref: 3D-NA145593

    1g
    5.164,00€
    50mg
    463,00€
    100mg
    724,00€
    250mg
    1.550,00€
    500mg
    2.821,00€
  • 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine

    CAS:
    1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine is a synthetic, modified nucleoside that can be phosphorylated to its monophosphate form. It is an inhibitor of DNA synthesis and the replication of viral DNA. 1-(2'-Chloro-2'-deoxy-b-D-arabinofuranosyl)cytosine has been shown to have anticancer activity in vitro and in vivo. This drug is also active against some RNA viruses such as hepatitis B virus and human immunodeficiency virus type 1 (HIV).
    Fórmula:C9H12ClN3O4
    Pureza:Min. 95%
    Peso molecular:261.66 g/mol

    Ref: 3D-NC29834

    5g
    A consultar
  • 7H-Pyrrolo[2,3d]pyrimidine

    CAS:
    <p>7H-Pyrrolo[2,3d]pyrimidine is a pyrimidine compound that has been shown to have potent antitumor activity. It inhibits the enzyme acyl-coenzyme A carboxylase (ACC) and blocks the production of malonyl-CoA, an intermediate in the metabolism of fatty acids. Malonyl-CoA is an allosteric activator of ACC, which is an important enzyme for regulating fatty acid synthesis. 7H-Pyrrolo[2,3d]pyrimidine also inhibits the expression of the gene encoding cb2 receptor, which is involved in inflammatory processes. The compound binds to a hydroxyl group on ACC to inhibit its activity. 7H-Pyrrolo[2,3d]pyrimidine has been shown to be effective against miapaca-2 cells and other cancer cell lines at concentrations as low as 1 nM. This compound also has a</p>
    Fórmula:C6H5N3
    Pureza:Min. 95%
    Peso molecular:119.12 g/mol

    Ref: 3D-NP32608

    1g
    303,00€
    5g
    813,00€
  • 7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt - 100mM aqueous solution

    CAS:
    7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt is a nucleoside analog that inhibits telomerase. It binds to the catalytic subunit of telomerase, which is an RNA-dependent DNA polymerase that synthesizes telomeres during DNA replication. This binding prevents the enzyme from extending the 3' end of the DNA strand, inhibiting cell proliferation and leading to apoptosis. Telomerase inhibition has been shown to have an inhibitory effect on insulin resistance in mice. 7-Deaza-2'-deoxyguanosine-5'-triphosphate lithium salt also inhibits protein kinases, but does not inhibit phosphatases or other enzymes.
    Fórmula:C11H17N4O13P3·xLi
    Pureza:Min. 95%
    Peso molecular:506.19 g/mol

    Ref: 3D-ND157323

    1mg
    349,00€
    2mg
    574,00€
    5mg
    906,00€
    10mg
    1.600,00€
    500µg
    300,00€
  • 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine


    <p>5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a nucleoside analog that has antiviral, anticancer, and high purity properties. It is an activated nucleotide that can be incorporated into DNA or RNA. 5-Chloro-5'-deoxy-5'-iodo-2',3'-O-isopropylidenecytidine is a modified nucleoside with the deoxyribose sugar replaced by an isopropylidene group. This modification prevents the drug from being metabolized and excreted from the body. The drug is used to treat various cancers such as leukemia and lymphoma, as well as herpes simplex virus infections. It also has been shown to have antimicrobial properties against bacteria, fungi, and viruses.</p>
    Fórmula:C12H15ClIN3O4
    Pureza:Min. 95%
    Peso molecular:427.63 g/mol

    Ref: 3D-NC04650

    100mg
    303,00€
    250mg
    497,00€
  • 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite

    CAS:
    <p>2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite is an antiviral agent that inhibits the synthesis of DNA. It can be used to treat AIDS, because it inhibits the reverse transcriptase enzyme. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-C2-methyladenosine 3'-CE phosphoramidite also has anticancer properties, which is due to its ability to inhibit RNA and protein synthesis in cancer cells. This compound has been synthesized by reacting 5'-O-DMT cytidine with methylacetoacetate under standard conditions. The modified nucleoside has a high purity, high quality, and novel structure.</p>
    Fórmula:C47H64N7O7Si
    Pureza:Min. 95%
    Peso molecular:867.14 g/mol

    Ref: 3D-NB139123

    1g
    2.380,00€
    2g
    4.136,00€
    250mg
    1.190,00€
    500mg
    1.883,00€
  • N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine

    CAS:
    <p>N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-7-iodoadenosine is a novel nucleoside that has been shown to have anticancer and antiviral properties. It is a phosphoramidite of 7-iodoadenosine that has been modified to contain a benzoyl group at the 6 position. N6-Benzoyl-7-deaza-2'-deoxy-5'-O-tert-butyldimethylsilyl-(7)iodoadenosine can be used for the synthesis of oligonucleotides and DNA, as well as for the activation of latent HIV genes. This compound is also used in vitro to study the interactions between phosphoramidites and nucleosides.</p>
    Fórmula:C24H31IN4O4Si
    Pureza:Min. 95%
    Peso molecular:594.52 g/mol

    Ref: 3D-NB165185

    1g
    1.954,00€
    2g
    3.159,00€
    500mg
    1.318,00€
  • 4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone


    <p>4-Amino-2,6-dimethyl-8-(2'-deoxy-3',5'-di-O-toluoyl-a-D-ribofuranosyl)-7-pteridone is a novel nucleoside that has been modified by the addition of a 2'-deoxy, 3',5'-di-O-toluoyl group on the sugar moiety. This modification increases the stability of 4AMDT in serum and enhances its antiviral activity against DNA and RNA viruses. It also inhibits the proliferation of cancer cells and induces cell death by inhibiting protein synthesis.</p>
    Fórmula:C29H29N5O6
    Pureza:Min. 95%
    Peso molecular:543.57 g/mol

    Ref: 3D-NA07206

    1mg
    315,00€
    2mg
    483,00€
    5mg
    793,00€
    10mg
    1.387,00€
    500µg
    300,00€
  • 2'-Deoxy-5-hydroxyuridine 5'-triphosphate

    CAS:
    <p>2'-Deoxy-5-hydroxyuridine 5'-triphosphate (doxorubicin) is a cytotoxic and chemotherapeutic agent that interferes with DNA replication. It is an oxidized form of the natural pyrimidine base thymine. The drug blocks DNA synthesis by preventing the incorporation of uracil into the newly synthesized strand, which causes strand breaks. Doxorubicin has been shown to be effective in treating a variety of cancers, including those of the breast, ovaries, bladder, and stomach. This drug can also cause severe side effects such as heart damage and hearing loss due to its interaction with cellular oxygen metabolism.</p>
    Pureza:Min. 95%

    Ref: 3D-ND168484

    10mg
    4.269,00€
  • 6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine

    CAS:
    <p>6-Chloro-9-(3',5'-di-O-benzoyl-2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)purine is a nucleoside that is used as an anticancer and antiviral agent. It is synthesized from 9-(3',5'-di-O-benzoyl)-2'-deoxyribofuranosyl chloride, which is then chlorinated to form 6-chloro purine. This product has been shown to be active against human DNA tumor cells and other viruses in vitro. 6CPA, like other nucleosides, can be phosphorylated on the 3' or 5' position of the sugar moiety, yielding monophosphate or diphosphate derivatives respectively. The monophosphate derivative of 6CPA has a higher cytotoxicity than the diphosphate derivative. The deoxyribose sugar moiety can</p>
    Fórmula:C24H18CIFN4O5
    Pureza:Min. 95%
    Peso molecular:496.89 g/mol

    Ref: 3D-NC08475

    25mg
    303,00€
    50mg
    314,00€
    100mg
    471,00€
  • Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt

    CAS:
    Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a neurotrophic factor that has been shown to have neuroprotective properties in different animal models of Parkinson's disease. It has been shown to promote the synthesis of dopamine, glutamate, and other neurotransmitters in dopaminergic neurons. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt also promotes protein production by stimulating the synthesis of intracellular proteins such as cytosolic Ca2+ and IGF-I. This drug may be effective in pharmacological treatment for Parkinson's disease. Adenosine 3',5'-cyclic monophosphothioate Rp-isomer sodium salt is a potent inhibitor of phosphodiesterase type 4 (PDE4) with a Ki value of 0.07 μM. This inhibition leads to the accumulation of cAMP, which activates protein kinase A (PKA
    Fórmula:C10H11N5O5PS·Na
    Pureza:Min. 95%
    Peso molecular:367.25 g/mol

    Ref: 3D-NA58197

    1mg
    394,00€
    2mg
    547,00€
    5mg
    1.096,00€
    10mg
    1.879,00€
    20mg
    3.050,00€
  • 1-(a-D-Mannopyranosyl)thymine

    CAS:
    1-(a-D-Mannopyranosyl)thymine is a phosphoramidite nucleoside with antiviral activity. It is an analog of thymine, in which the oxygen atom at the 5-position has been replaced by a mannose group and the hydroxyl group at the 4-position has been replaced by a methyl group. This compound has shown to have anticancer properties as well as inhibitory effects on HIV replication. Studies have also shown that 1-(a-D-mannopyranosyl)thymine inhibits proliferation and induces apoptosis in human cancer cell lines.
    Fórmula:C11H16N2O7
    Pureza:Min. 95%
    Cor e Forma:Light (Or Pale) Yellow Solid
    Peso molecular:288.75 g/mol

    Ref: 3D-NM09535

    100g
    A consultar
  • 3'-Azido-3'-deoxy-5-methylcytidine

    CAS:
    <p>3'-Azido-3'-deoxy-5-methylcytidine (AZDMC) is a novel nucleoside analog that inhibits viral replication. AZDMC is an activator of cellular DNA synthesis, which is essential for the replication of DNA and the production of RNA. It also has antiviral activity against influenza A and B viruses. The chemical name for AZDMC is 3'-azido-3'-deoxy-5-methylcytidine monophosphate (AMP). The CAS number for AZDMC is 1282040-14-5. It can be synthesized with high purity and quality by Ribonucleosides, Modified, Deoxyribonucleosides, Nucleosides, Phosphoramidites.</p>
    Pureza:Min. 95%

    Ref: 3D-NA163051

    5mg
    303,00€
    10mg
    357,00€
    25mg
    596,00€
  • N6-Benzoyl-3'-deoxyadenosine

    CAS:
    N6-Benzoyl-3'-deoxyadenosine is a nucleoside analogue that is used as a substrate for DNA polymerase. The efficiency of this compound has been shown to be higher than other nucleotides. In addition, N6-Benzoyl-3'-deoxyadenosine has been shown to be an efficient donor in the ligation reaction and can also act as a competitive inhibitor of topoisomerase II. N6-Benzoyl-3'-deoxyadenosine is a scissile substrate for DNA topoisomerase II and cleaves at the same site as dATP. This compound has been shown to be active against both Gram-positive bacteria and Mycobacterium tuberculosis with high selectivity.
    Fórmula:C17H17N5O4
    Pureza:Min. 95%
    Peso molecular:355.35 g/mol

    Ref: 3D-NB31303

    50mg
    303,00€
    100mg
    364,00€
    250mg
    702,00€
    500mg
    1.152,00€