Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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3-Deazauridine 5'-O-triphosphate lithium salt - 100 mM aqueous solution
3-Deazauridine 5'-O-triphosphate lithium salt is a nucleotide that can be found in the monophosphate form. It is an activator of RNA polymerase and is used to synthesize DNA. 3-Deazauridine 5'-O-triphosphate lithium salt functions as a novel anticancer agent, inhibiting the synthesis of DNA. This substance is also used as a building block for phosphoramidites and as a reagent for DNA synthesis.Pureza:Min. 95%N4-Benzoyl-1-(3-O-methyl-b-D-xylofuranosyl)cytosine
N4-Benzoyl-1-(3-O-methyl-β-D-xylofuranosyl)cytosine is a modified nucleoside analog used in the treatment of cancer. It has been shown to be effective in the treatment of leukemia and lymphoma. N4-Benzoyl-1-(3-O-methyl-β-D-xylofuranosyl)cytosine inhibits viral DNA synthesis and is also an effective antiviral agent against HIV. This compound has been shown to have anticancer properties, which may be due to its ability to inhibit DNA replication and protein synthesis.Pureza:Min. 95%2,2'-Anhydrouridine
CAS:The nucleophilic opening of 2,2'-Anhydrouridine represents a novel synthetic approach for elaborating the ring of nucleosides. For example, compounds such as 2-amino-, 2-fluoro- and 2-phenylseleno-2-deoxyuridines are prepared from the nucleophilic opening of 2,2'-Anhydrouridine.Â2,2'-Anhydrouridine inhibits uridine phosphorylase, a key enzyme targeted by some antitumor drugs.
Fórmula:C9H10N2O5Pureza:Min. 98 Area-%Cor e Forma:White Off-White PowderPeso molecular:226.19 g/molOrotidine 5'-monophosphate trisodium salt
CAS:Ribonuclesides is a novel nucleoside that contains the 2'-deoxyribose phosphate moiety. It is an anticancer drug that inhibits DNA synthesis and blocks viral replication. Ribonucleosides are phosphoramidites and can be used for the synthesis of DNA or RNA, which are important for cellular metabolism. Ribonucleosides also have antiviral properties and can inhibit protein synthesis by blocking the enzyme ribonucleotide reductase.Fórmula:C10H10N2O11PNa3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:434.14 g/molN6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine
CAS:N6-Benzoyl-2'-O-tert-butyldimethylsilyladenosine (BTS) is a novel phosphoramidate monophosphate nucleoside analog that has been modified to be resistant to the ribonuclease A enzyme. BTS is an activator of DNA synthesis and inactivator of RNA synthesis, which makes it useful for the treatment of cancer and antiviral infections. This drug is synthesized using high quality reagents and can be used for the production of phosphoramidites to produce high purity oligonucleotides.Fórmula:C23H31N5O5SiPureza:Min. 95%Cor e Forma:PowderPeso molecular:485.61 g/molN6-Methyl-2'-C-methyladenosine
CAS:N6-Methyl-2'-C-methyladenosine is a modified nucleoside that belongs to the category of Deoxyribonucleosides. It is a novel compound with antiviral, anticancer, and antitumor properties. N6-Methyl-2'-C-methyladenosine inhibits viral replication by blocking the synthesis of DNA. This compound also has antiproliferative effects on cancer cells and retards tumor growth in animal models. N6-Methyl-2'-C-methyladenosine is synthesized from phosphoramidites in a two step process: first, the addition of methyl iodide to the phosphorus atom followed by nucleophilic substitution with methylamine.Fórmula:C12H17N5O4Pureza:Min. 95%Peso molecular:295.29 g/mol1-(b-L-Arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt
1-(b-L-Arabinofuranosyl)uracil 5'-triphosphate triethylammonium salt is a novel antiviral agent that is synthesized from ribonucleosides. It is an activator of the monophosphate form of RNA polymerase and inhibits the synthesis of DNA in cells. This drug has also been shown to be effective against cancer cells and may be useful for treatment of leukemia.Pureza:Min. 95%5'-Azido-5'-deoxyadenosine
CAS:5'-Azido-5'-deoxyadenosine (Aza-dA) is an adenosine analog that inhibits the deamination of S-adenosylhomocysteine to form adenosine. It has been shown to be more potent than 2-chloroadenosine and inactivates the enzyme s-adenosylhomocysteine hydrolase, which is responsible for the conversion of S-adenosylhomocysteine to adenosine. This leads to decreased levels of adenosine and increased levels of s-adensoylhomocysteine. Aza-dA has been shown to inhibit tumor growth and induce apoptosis in rat hepatocytes. In addition, it is a halogenated molecule that can be used as a modifying agent.Fórmula:C10H12N8O3Pureza:Min. 95%Cor e Forma:PowderPeso molecular:292.25 g/mol2'-O-Methyl-N6-phenoxyacetyladenosine
CAS:2'-O-Methyl-N6-phenoxyacetyladenosine is a phosphoramidite nucleoside that is used in the synthesis of DNA and RNA. It has antiviral, anticancer, and antiribonucleases properties. The chemical structure of 2'-O-Methyl-N6-phenoxyacetyladenosine is similar to that of adenosine, but contains a methyl group on C2' position and an oxyalkyl group on N6. This compound can be used as a novel anticancer agent and has been shown to have high affinity for the purine receptor, inhibiting cancer cell proliferation by activating the p53 tumor suppressor pathway.Fórmula:C19H21N5O6Pureza:Min. 95%Cor e Forma:White to off-white solid.Peso molecular:415.41 g/mol2'-Deoxy-2'-fluorouridine
CAS:2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA.Fórmula:C9H11FN2O5Pureza:Min. 95%Cor e Forma:White Off-White PowderPeso molecular:246.2 g/mol9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine
CAS:9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine is a modified monophosphate nucleoside that is an antiviral agent. It can be used as a building block for the synthesis of ribonucleosides, deoxyribonucleosides, and phosphoramidites. This product has been shown to have anticancer properties and may be used in the development of new anticancer drugs. 9-(2'-C-methyl-b-D-ribofuranosyl)6-methylpurine has also been shown to inhibit the growth of bacteria by inhibiting DNA synthesis.Pureza:Min. 95%2,6-Diamino-9-(2'-deoxy-2'-fluoro-β-D-ribofuranosyl)purine
CAS:2,6-Diamino-9-(2'-deoxy-2'-fluoro-β-D-ribofuranosyl)purine is a modified purine nucleoside analog. This compound has modification that have the potential to influence its ability to interfere with nucleic acid synthesis, such as DNA or RNA.Fórmula:C10H13FN6O3Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:284.25 g/mol8-Azidoadenosine 5'-monophosphate sodium salt
CAS:8-Azidoadenosine 5'-monophosphate sodium salt is an azido-conjugated adenosine monophosphate derivative used to introduce a label on oligonucleotides. A click reaction between the azide-functionalised nucleotide and a terminal alkyne-functionalised labelled moiety (with either a fluorophore or biotin) generates a stable conjugate containing a triazole link.Fórmula:C10H13N8O7PPureza:Min. 95%Peso molecular:388.23 g/mol5-Formylcytidine
CAS:5-Formylcytidine is a nucleoside that belongs to the group of pyrimidine nucleosides. It is structurally similar to cytidine, but with a formyl group in place of the hydroxymethyl group on the C5 position. 5-Formylcytidine has been shown to have an inhibitory effect on mitochondrial protein synthesis and cellular functions in mammalian cells.Fórmula:C10H13N3O6Pureza:Min. 97 Area-%Cor e Forma:White Off-White PowderPeso molecular:271.23 g/mol2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite
2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3-methylcytidine 3'-CE phosphoramidite is a modified nucleoside that is synthesized by the reaction of 2'-deoxycytidine with bis(2,4,6-trichlorophenyl)carbonate in the presence of a base. 2'-O-tert-Butyldimethylsilyl-5'-O-DMT-N3 methylcytidine 3'-CE phosphoramidite has been shown to have anticancer activity and is used as an activator in the synthesis of oligonucleotides. This product is available as a white powder and can be used for research purposes only.Pureza:Min. 95%Adenosine 5'-diphosphate magnesium salt
CAS:Adenosine 5'-diphosphate magnesium salt (ADP-Mg) is a pharmacological agent that has inhibitory properties. It is used as a model system to study platelet function and the effect of adenosine on platelet aggregation. ADP-Mg is also used as a reagent in the study of protein synthesis and regulation. This chemical has been shown to potentiate the activity of serotonin receptors, which may contribute to its anti-inflammatory effects. Adenosine 5'-diphosphate magnesium salt also inhibits papillary muscle contractions by inhibiting Ca2+ currents, leading to an improved ejection fraction in patients with congestive heart failure.Fórmula:C10H13N5O10P2·MgPureza:Min. 95%Cor e Forma:PowderPeso molecular:449.49 g/mol7-Deaza-2'-deoxy-7-iodoguanosine
CAS:7-Deaza-2'-deoxy-7-iodoguanosine is a purine nucleoside that is synthesized from guanosine and iodine. It is used as a marker in sequencing reactions because it can be easily detected by UV light at 254 nm. 7-Deaza-2'-deoxy-7-iodoguanosine can be synthesized using the following general equation:
Fórmula:C11H13IN4O4Pureza:Min. 97 Area-%Cor e Forma:White PowderPeso molecular:392.16 g/molN4-Benzoyl-2-aza-3’-deazaadenine
CAS:N4-Benzoyl-2-aza-3’-deazaadenine is a modified nucleoside that is synthesized from the natural deoxyribonucleoside adenine. It has been shown to have antiviral and anticancer properties. N4-Benzoyl-2-aza-3’-deazaadenine is a DNA Activator and can be used in the treatment of viral infections, such as HIV and herpes, as well as cancer. The drug binds to the viral DNA polymerase and prevents it from making new copies of the virus. This results in an accumulation of defective viruses within infected cells and ultimately cell death.Pureza:Min. 95%2-Thiocytidine
CAS:2-Thiocytidine is a nucleoside that is an intermediate in the synthesis of thiamine. It has been shown to be effective in the treatment of prostate cancer cells, which may be due to its ability to inhibit protein synthesis. 2-Thiocytidine binds to the catalytic site of ribonucleotide reductase (RR) and inhibits the enzyme's activity, thereby inhibiting DNA synthesis. This drug also has been shown to inhibit crosslinking caused by UV light or other agents that generate reactive oxygen species. 2-Thiocytidine binds to the active site of RR and prevents the formation of the enzyme-substrate complex. This binding prevents reduction of ribose into ribonucleotides and inhibits DNA synthesis.
Fórmula:C9H13N3O4SPureza:Min. 95%Cor e Forma:Yellow PowderPeso molecular:259.28 g/mol2'-Deoxy-5-(2-iodoethyl)uridine
CAS:2'-Deoxy-5-(2-iodoethyl)uridine is a nucleoside analog with antiviral and anticancer activity. It has been shown to be an activator of DNA replication, as well as inhibiting the synthesis of deoxyribonucleotides. This drug also has a novel structure that is modified from the natural nucleosides found in DNA and RNA. 2'-Deoxy-5-(2-iodoethyl)uridine can be synthesized using phosphoramidites, which are activated by iodine and sulfurizing agents. The purity of this compound is high and it is available at high quality.Pureza:Min. 95%
