Nucleosídeos
Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.
Foram encontrados 3569 produtos de "Nucleosídeos"
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3-N-Boc-5'-O-DMT-3'-fluorothymidine
CAS:3-N-Boc-5'-O-DMT-3'-fluorothymidine is a monophosphate nucleoside with antiviral and anticancer activity. It is a novel synthetic analogue of fluoro thymidine (FT) that has been shown to be an activator of DNA polymerase α, RNA polymerase β and γ, and protein kinase C. This compound is also an inhibitor of the reverse transcriptase enzyme HIV-1. 3-N-Boc-5'-O-DMT-3'-fluorothymidine has been shown to inhibit cancer cell growth in vitro and in vivo. The synthesis of this compound can be achieved by phosphoramidite chemistry using a commercially available automated synthesizer.Pureza:Min. 95%trans-Zeatin riboside
CAS:Trans-zeatin riboside is a cytokinin that is structurally related to adenosine. It has been shown to inhibit the adenosine a3 receptor, which decreases the production of reactive oxygen species in human serum and enhances the uptake of glucose. Trans-zeatin riboside also inhibits nuclear DNA fragmentation and increases water permeability in plant tissues. This chemical has been shown to stimulate photosynthetic activity in plants at an optimum concentration of 10 μg/ml. Trans-zeatin riboside should be stored at -20 degrees Celsius for long-term storage.Fórmula:C15H21N5O5Cor e Forma:White Off-White PowderPeso molecular:351.36 g/molN6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite
CAS:N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is an antiviral nucleoside phosphoramidite that is used in the synthesis of DNA. It has been shown to have antiviral activity against HIV and herpes, as well as anticancer effects. It also has high purity, being a novel synthetic nucleoside with a CAS number. N6-Benzoyl-3'-O-tert-butyldimethylsilyl-5'-O-DMT-adenosine 2'-CE phosphoramidite is synthesized using novel methods. The synthesis process includes activation with diphosphate, DNA, and Novel nucleosides, which are high quality and modified.Fórmula:C53H66N7O8PSiPureza:Min. 95%Cor e Forma:PowderPeso molecular:988.19 g/molGuanosine-5'-[(b,gamma)-methyleno]triphosphate sodium salt
CAS:Guanosine-5'-[(b,gamma)-methyleno]triphosphate sodium salt (GMPP) is an analog of guanosine triphosphate that is enzymatically inactivated by the enzyme kinesin. GMPP inhibits the polymerization of microtubules by binding to the kinesin molecule and preventing it from binding to tubulin. GMPP has been shown to inhibit sephadex g-100 chromatography and act as a competitive inhibitor for protein synthesis in vitro. GMPP has also been shown to have a fat cell differentiation effect which may be due to its ability to inhibit microtubule polymerization.Fórmula:C11H18N5O13P3·xNaPureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:521.21 g/mol2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite
2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is a novel nucleoside analog that has been synthesized to have the same chemistry as 2,3'-dideoxycytidine 5'-C phosphoramidite. It has antiviral and anticancer properties. This compound can be used in the synthesis of oligonucleotides for DNA sequencing and for gene therapy. 2,3'-Anhydro-N4-benzoyl-2'-deoxycytidine 5'-CE phosphoramidite is not toxic to normal cells, but it inhibits replication of viruses such as HIV and herpes simplex virus.Fórmula:C25H32N5O5PPureza:Min. 95%Peso molecular:513.54 g/mol5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine
CAS:5’-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine is an antiviral drug that inhibits the synthesis of viral DNA. It is synthesized by reacting 5'-deoxyadenosine monophosphate with 2'-O-(2-methoxyethyl)iodoacetamide and methylating the resulting product with methyl iodide. 5'-Deoxy-5’-iodo-2’-O-(2-methoxyethyl)-5-methyluridine has a novel structure and can be used as an activator of ribonucleosides in DNA synthesis. The drug also has anticancer properties, which may be due to its ability to inhibit cellular proliferation by inhibiting the enzyme DNA polymerase or by arresting cells at the G1 phase of the cell cycle.Pureza:Min. 95%N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine
CAS:N4-Acetyl-2'-deoxy-5'-O-DMT-2'-fluorocytidine is a cytosine analog with high affinity for the T cell receptor. It can be used to generate antibodies against cytosine and as a screening tool for plasmon resonance.
Fórmula:C32H32FN3O7Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:589.61 g/mol4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine
CAS:4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine is a novel nucleoside analog with antiviral and anticancer activities. It is a chemical compound with the molecular formula C8H14N6O5P and a molecular weight of 288.28 g/mol. 4'-C-Azido-2'-deoxy-2'-fluoro-4-[bis(2-hydroxyethyl)]-b-D-arabinocytidine has the CAS number 136045902, which can be found in PubChem Compound Database.Pureza:Min. 95%1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine
1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine is a deoxyribonucleoside, modified nucleoside that is synthesized by using a novel phosphoramidite chemistry. 1-(4’-Azido-2’-deoxy-2’-fluoro-b-D-arabinofuranosyl)N4-(n-palmitoyl)-cytosine is an activator of ribonucleotide reductase and can be used in anticancer and antiviral therapy.Pureza:Min. 95%N6-Dimethyl-3’-b-C-methyladenosine
CAS:N6-Dimethyl-3’-b-C-methyladenosine is a novel nucleoside analog that has antiviral and anticancer properties. It is a phosphoramidite, which can be used as an activator for the synthesis of modified oligonucleotides. N6-Dimethyl-3’-b-C-methyladenosine has been shown to activate ribonucleosides and deoxyribonucleosides in vitro. This compound also has anticancer properties, which may be due to its ability to act as an activator in the synthesis of DNA.Pureza:Min. 95%1'-13CCytidine
CAS:Please enquire for more information about 1'-13CCytidine including the price, delivery time and more detailed product information at the technical inquiry form on this pageFórmula:CC8H13N3O5Pureza:Min. 95%Cor e Forma:PowderPeso molecular:244.21 g/mol2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate
2'-O-(2-Methoxyethyl)-5-methyluridine 5'-monophosphate is an antiviral nucleoside with anticancer properties that is synthesized from 2'-deoxyuridine monophosphate and 5-methyluridine. This novel compound has shown antiviral activity against HIV, herpes simplex virus type 1, and herpes simplex virus type 2. It also inhibits the growth of human breast cancer cells in vitro.Pureza:Min. 95%5'-O-p-Anisoyl-D3-thymidine
Produto Controlado5'-O-p-Anisoyl-D3-thymidine is a nucleoside analogue that is used in antiviral and anticancer treatments. It is synthesized by the condensation of 3,4-dihydroxyacetophenone with 2,6-diaminopurine followed by phosphorylation of the 5' hydroxyl group. This product has been shown to be an activator of both DNA polymerase and RNA polymerase. In addition, it can inhibit the production of viral proteins such as HIV protease without affecting protein synthesis in mammalian cells. It also inhibits cancer cell growth by stopping DNA replication at the G2 phase. 5'-O-p-Anisoyl-D3-thymidine has been shown to be highly purified and can be used for research purposes. This product may have a CAS number but it will not be listed on this website due to company policy.Fórmula:C18H17N2O7D3Pureza:Min. 95%Peso molecular:379.38 g/mol3',5’-Bis-O-tert-butyldimethylsilyl-2’-O-methyl-5-methylcytidine
3',5' bis-O-tert-butyldimethylsilyl-2'-O-methyl-5'-methylcytidine is a synthetic nucleoside that is used in the synthesis of DNA and RNA. It can be activated by phosphoramidites for use in oligonucleotide synthesis. This nucleoside has been shown to be an effective activator for DNA polymerase, which is vital for the replication of DNA. 3',5' bis-O-tert-butyldimethylsilyl-2'-O-methyl-5'-methylcytidine has also been shown to inhibit viral replication, including HIV and herpes simplex virus type 1. This compound is a novel monophosphate nucleoside that has been modified with a tert butyl group on the 5' position and an O methyl group on the 2' position. It also contains an additional methyl group at the 5' carbon atom of cytidinePureza:Min. 95%N2-Phenylacetyl-L-guanosine
N2-Phenylacetyl-L-guanosine is a nucleoside that has been synthetically modified to have the desired properties of an anticancer agent. This compound inhibits DNA synthesis and is therefore cytotoxic to cells. It also inhibits RNA synthesis and is antiviral. N2-Phenylacetyl-L-guanosine has been found to be effective in preventing the growth of leukemia cells, breast cancer cells, prostate cancer cells, and ovarian cancer cells. N2-Phenylacetyl-L-guanosine is a nucleotide analogue that can be used as a building block for DNA or RNA synthesis. It can be used as a phosphate donor in phosphoramidite chemistry and can activate other nucleosides for use in chemical biology.
Fórmula:C18H19N5O6Pureza:Min. 95%Peso molecular:401.37 g/mol2'/3'-O-(N-Methylanthraniloyl)-N6-methyl-adenosine-5'-triphosphate triethylammonium salt
2'/3'-O-(N-Methylanthraniloyl)-N6-methyl-adenosine-5'-triphosphate triethylammonium salt is a nucleoside phosphoramidite. It is modified with a methylanthranilic acid group and an aminopropyl moiety at the 2' and 3' positions of the ribose sugar moiety. It has antiviral, anticancer, and novel properties. This compound is synthesized by reacting 2',3'-O-(dimethoxytrityl) -N6-methyl-adenosine-5'-triphosphate with triethylamine in the presence of a base like pyridine or DBU.Fórmula:C19H25N6O14P3Pureza:Min. 95%Peso molecular:654.36 g/mol4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
CAS:4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a nucleoside monophosphate that is used as an antiviral agent. It inhibits the synthesis of viral DNA and RNA by inhibiting the activity of enzymes needed for nucleotide synthesis. 4,6-Diamino-2-(b-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine has shown anticancer properties in vitro against human colon cancer cells. This drug has been shown to inhibit the growth of tumor cells with high expression levels of cyclin D1 and low levels of p27 (a cell cycle regulatory protein).Pureza:Min. 95%4-Amino-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
CAS:4-Amino-7-(2-C-methyl-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile (PMPC) is a novel antiviral agent. It is highly active against HIV and has shown to be effective against herpes simplex virus type 1 (HSV1) and HSV type 2 (HSV2). PMPC inhibits the synthesis of viral DNA by phosphorylating a monophosphate residue on the ribonucleoside triphosphate substrate. This prevents the enzyme from adding another phosphate group to the nucleotide sequence, which prevents further DNA synthesis. PMPC also has anticancer properties due to its ability to inhibit cell proliferation by preventing the formation of deoxyribonucleosides and diphosphates.
Fórmula:C13H15N5O4Pureza:Min. 95%Peso molecular:305.29 g/molN4-Acetylcytidine
CAS:N4-Acetylcytidine is a modified nucleoside and endogenous urinary nucleoside product of the degradation of tRNA. N4-Acetylcytidine is a biological marker for various cancers with elevated concentrations present in urine. N4-Acetylcytidine is also a partially protected cytidine and therefore can be used as a synthetic building block to prepare further derivatized nucleosides such as 2’,3’-dideoxycytidine.Fórmula:C11H15N3O6Pureza:Min. 95%Cor e Forma:White PowderPeso molecular:285.25 g/mol5'-Amino-5'-deoxyguanosine
CAS:5'-Amino-5'-deoxyguanosine (5-ADG) is an intermediate in the de novo synthesis of guanine nucleotides. It can be synthesized from 5-aminoimidazole ribonucleotide and guanosine monophosphate (GMP). 5-ADG is a substrate for the enzyme GTP cyclohydrolase, which converts it to GMP. This intermediate can also be formed by the action of phosphoryl chloride on 5-aminoimidazole ribonucleotide. The reaction of 5-ADG with malonic acid leads to the formation of inosinic acid, which has been postulated to be a precursor of purines. This conversion is catalyzed by adenylosuccinate synthetase and the enzyme adenylosuccinase.Fórmula:C10H14N6O4Pureza:Min. 95 Area-%Cor e Forma:PowderPeso molecular:282.26 g/mol
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