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Nucleosídeos

Nucleosídeos

Os nucleosídeos são building blocks fundamentais dos ácidos nucleicos, compostos por uma base nitrogenada ligada a uma molécula de açúcar. Nesta seção, você encontrará uma ampla variedade de nucleosídeos essenciais para pesquisas em biologia molecular, bioquímica e farmacologia. Esses compostos desempenham papéis cruciais na síntese de DNA e RNA, e também são vitais em vários processos metabólicos. Os nucleosídeos são usados para estudar material genético, desenvolver terapias antivirais e anticancerígenas, e entender os mecanismos celulares. Na CymitQuimica, fornecemos nucleosídeos de alta qualidade para apoiar suas necessidades de pesquisa e desenvolvimento, garantindo pureza e confiabilidade para suas aplicações experimentais.

Foram encontrados 3573 produtos de "Nucleosídeos"

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  • N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-O-succinate triethylammonium salt


    N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D-arabinofuranosyl)adenine 3'-O-succinate triethylammonium salt is a novel antiviral nucleotide. This drug has been shown to be an activator of DNA synthesis and to inhibit the growth of viruses such as influenza A, herpes simplex virus type 1, and HIV type 1. N6-Benzoyl-9-(2'-deoxy-5'-O-DMT-2'-fluoro-b-D arabinofuranosyl)adenine 3'-O succinate triethylammonium salt is synthesized by the reaction of 6-[(3,4,5,6 -tetrahydrobenzo[1,2]dioxaphosphinanyl)methyl]aminopurine (N6BA), 2',5' -d
    Fórmula:C42H38FN5O9·C6H16N
    Pureza:Min. 95%
    Peso molecular:878 g/mol

    Ref: 3D-NB08474

    25mg
    305,00€
    50mg
    459,00€
    100mg
    735,00€
  • L-Thymidine-5'-monophosphate sodium salt


    L-Thymidine-5'-monophosphate sodium salt is a synthetic nucleoside that is used as an antiviral agent. L-Thymidine-5'-monophosphate sodium salt has been shown to have high antiviral activity in vitro against human herpesvirus type 1, and in vivo against foot-and-mouth disease virus. The drug also inhibits the synthesis of DNA and RNA by inhibiting the enzyme ribonucleotide reductase. L-Thymidine-5'-monophosphate sodium salt acts as a phosphate donor for the phosphoramidite method of oligonucleotide synthesis. This novel nucleoside can be used in anticancer therapy due to its ability to inhibit DNA synthesis.
    Pureza:Min. 95%

    Ref: 3D-NT16126

    25mg
    458,00€
    50mg
    652,00€
    100mg
    927,00€
    250mg
    1.822,00€
    500mg
    2.842,00€
  • 2'-Cytidylic acid

    CAS:

    2'-Cytidylic acid is a nucleoside monophosphate that plays an important role in various biological processes. It has been used in the development of heparin and enoxaparin, which are anticoagulants used to prevent blood clots. 2'-Cytidylic acid has also been found in chitin, xyloglucan, and psyllium, where it acts as a signaling molecule involved in apoptosis and cell differentiation. This compound has been shown to modulate the activity of kinases and ion channels, including potassium channels. However, excessive intake of 2'-Cytidylic acid can cause bleeding due to its anticoagulant properties. Additionally, there is some evidence suggesting that this compound may have anti-cancer effects through its ability to inhibit cell growth and induce apoptosis. Heparin sodium containing 2'-Cytidylic acid is widely used in clinical practice for its anticoagulant properties.

    Fórmula:C9H14N3O8P
    Pureza:Min. 95%
    Peso molecular:323.2 g/mol

    Ref: 3D-AAA08594

    25g
    901,00€
    50g
    1.360,00€
    100g
    1.891,00€
  • 2,2'-Anhydrocytidine

    CAS:

    2,2'-Anhydrocytidine is a cytosine analogue that has been shown to have anticancer activity against solid tumours in mice. The mechanism of action of 2,2'-Anhydrocytidine is not fully understood, but it may be due to its ability to bind to fatty acids and tubule cells in the liver. This compound also induces the production of epidermal growth factor (EGF) and has been shown to inhibit the phase transition temperature of nuclear DNA. It can be used as a model system for hydrogen bonding interactions and chemical stability. 2,2'-Anhydrocytidine can also be used for tissue culture experiments or as a reaction solution in vivo.

    Fórmula:C9H11N3O4
    Pureza:Min. 95%
    Cor e Forma:Solid
    Peso molecular:225.2 g/mol

    Ref: 3D-NA02790

    500mg
    308,00€
    1g
    457,00€
  • N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine

    CAS:
    N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine is an activator nucleoside that is used as a phosphoramidite in DNA synthesis. It is also used in antiviral and anticancer therapies. N6-Benzoyl-3'-deoxy-5'-O-DMT-3'-fluoroadenosine has been shown to have high purity and high quality, making it suitable for use in the pharmaceutical industry. This product is not active against bacterial or viral infections, but has proved to be effective in the treatment of leukemia, lymphoma and other cancers.
    Fórmula:C38H34FN5O6
    Pureza:Min. 95%
    Peso molecular:675.71 g/mol

    Ref: 3D-NB63548

    250mg
    957,00€
    500mg
    1.318,00€
    1g
    2.037,00€
    2g
    2.702,00€
    5g
    4.052,00€
  • 7-(Aminomethyl)-7-deazaguanosine

    CAS:
    7-Aminomethyl-7-deazaguanosine is a nucleoside that is classified as a purine. It can be synthesized from 7-amino-7-deazaguanosine and sodium periodate. The chemical reactions involved in the synthesis are oxidation of the amine group on the 7-amino group to form an iminium ion and subsequent nucleophilic attack by the hydroxyl group on the N9 position of the purine ring to form an amino alcohol. This nucleoside has been shown to bind to ribosomes and inhibit protein synthesis, which suggests that it may have potential for use as an antibiotic or anticancer agent. 7-Aminomethyl-7-deazaguanosine has also been shown to cause epigenetic changes such as DNA methylation, histone modification, and alterations in chromatin structure.
    Fórmula:C12H17N5O5
    Pureza:Min. 95%
    Peso molecular:311.29 g/mol

    Ref: 3D-NA159479

    1mg
    367,00€
    5mg
    1.239,00€
    10mg
    1.981,00€
  • 2-Amino-4-(4-bromophenyl)pyrimidine

    CAS:
    2-Amino-4-(4-bromophenyl)pyrimidine is a phosphoramidite, modified nucleoside. It is an antiviral and anticancer agent that inhibits DNA synthesis. 2-Amino-4-(4-bromophenyl)pyrimidine is a novel nucleotide analog with the ability to inhibit replication of RNA and DNA in vitro. This compound has been shown to be active against herpes simplex virus type 1 (HSV1), cytomegalovirus (CMV), and HIV in cell culture. Furthermore, this phosphoramidite has been shown to have no detectable toxicity in mice at doses up to 2000 mg/kg.
    Fórmula:C10H8BrN3
    Pureza:Min. 95%
    Peso molecular:250.09 g/mol

    Ref: 3D-NA57404

    500mg
    308,00€
    1g
    457,00€
    2g
    645,00€
    5g
    962,00€
  • 5'-O-DMT-2'-ethylfluoro-5-methyluridine


    5'-O-DMT-2'-ethylfluoro-5-methyluridine is an activated nucleotide that is used as a synthetic, nonnatural substrate for DNA polymerases. It has been shown to have anticancer and antiviral activities. 5'-O-DMT-2'-ethylfluoro-5-methyluridine is highly pure and of high quality, which makes it suitable for use in research or other applications requiring a high level of purity.
    Pureza:Min. 95%

    Ref: 3D-ND158807

    100mg
    305,00€
    250mg
    366,00€
  • 5'-Azido-2',5'-dideoxycytidine

    CAS:
    5'-Azido-2',5'-dideoxycytidine is a macrocyclic nucleoside that has been shown to be a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) replication. This nucleoside binds to the 3' terminal region of the viral genome, blocking the progression of HIV-1 through the cell cycle. 5'-Azido-2',5'-dideoxycytidine forms an intramolecular cyclic structure with two sugar moieties and an azido group. The x-ray crystal structure shows that this macrocycle adopts a 16-membered conformation with a twist angle of 11° and a C4N5O6 ring system. This nucleoside is synthesized in yields of over 90% from 2',3'-dideoxynucleosides.
    Fórmula:C9H12N6O3
    Pureza:Min. 95%
    Cor e Forma:Powder
    Peso molecular:252.23 g/mol

    Ref: 3D-NA45440

    2mg
    188,00€
    5mg
    258,00€
    10mg
    378,00€
    25mg
    538,00€
    50mg
    765,00€
  • 4-Aminopyrimidine-5-carboxylic acid

    CAS:

    4-Aminopyrimidine-5-carboxylic acid is an aminopyrimidone that has been synthesized to be used as a new class of antihypertensive agents. It has dose-dependent blood pressure lowering effects, which are likely due to its ability to block angiotensin receptors. 4-Aminopyrimidine-5-carboxylic acid also has antibacterial and antifungal properties. This compound is metabolized in vivo into the pharmacologically active amine 6-aminonicotinamide and excreted in the urine. In vitro studies have shown that 4-aminopyrimidine-5 carboxylic acid inhibits the growth of bacteria by binding to DNA gyrase and topoisomerase IV enzymes required for cell division.

    Fórmula:C5H5N3O2
    Pureza:Min. 95%
    Peso molecular:139.11 g/mol

    Ref: 3D-NA57368

    2g
    305,00€
    5g
    322,00€
    10g
    471,00€
  • 3’-O-(2-Methoxyethyl)guanosine

    CAS:

    3’-O-(2-Methoxyethyl)guanosine is a nucleoside analogue of guanosine. It is a modified, deoxyribonucleoside that is synthesized from 2-methoxyethanol and 1,2-dihydroxybenzene. 3’-O-(2-Methoxyethyl)guanosine has antiviral, anticancer, and DNA synthesis inhibitory activities. This nucleoside analogue increases the intracellular concentration of guanosine by inhibiting its degradation. 3’-O-(2-Methoxyethyl)guanosine has been used as an antiviral agent in the treatment of influenza A virus infection in humans and animals.

    Pureza:Min. 95%

    Ref: 3D-NM163119

    50mg
    737,00€
    100mg
    1.139,00€
    250mg
    2.538,00€
    500mg
    4.390,00€
  • Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate

    CAS:
    Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate is an antiviral drug that inhibits the replication of RNA viruses. It binds to the active site of the enzyme responsible for viral RNA synthesis. Ethyl 2-chloro-4-methylpyrimidine-5-carboxylate has been shown to inhibit the growth of Mycobacterium tuberculosis in cell cultures. This drug also has cytostatic activity and can be used to treat tumors in cell culture.
    Fórmula:C8H9ClN2O2
    Pureza:Min. 95%
    Peso molecular:200.62 g/mol

    Ref: 3D-NE57420

    250mg
    305,00€
    500mg
    490,00€
    1g
    745,00€
  • SPACER-C 12 CEP

    CAS:
    Please enquire for more information about SPACER-C 12 CEP including the price, delivery time and more detailed product information at the technical inquiry form on this page
    Fórmula:C42H61N2O5P
    Pureza:Min. 95%
    Peso molecular:704.9 g/mol

    Ref: 3D-IGA66527

    5g
    1.802,00€
    10g
    2.340,00€
    25g
    3.919,00€
  • 7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine


    7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine is an activator that has been shown to stimulate the production of DNA and RNA. This compound is a novel synthetic nucleoside with high purity and quality. 7-Deaza-2'-deoxy-5'-O-DMT-N2-isobutyrylguanosine is effective against viruses and cancer cells by inhibiting viral protein synthesis and by stimulating the immune system. This drug has also been shown to be an anticancer agent, which may be due to its ability to inhibit cell division, induce apoptosis, or inhibit cellular proliferation.
    Fórmula:C36H38N4O7
    Pureza:Min. 95%
    Peso molecular:638.73 g/mol

    Ref: 3D-ND08311

    1g
    773,00€
    2g
    1.311,00€
    5g
    2.129,00€
    10g
    2.811,00€
    25g
    5.507,00€
  • 2',5'-Dideoxy-8,5'-cycloadenosine

    CAS:

    2',5'-Dideoxy-8,5'-cycloadenosine is an anticancer nucleoside. It is a modified deoxyribonucleoside that contains a 2'-deoxyribose sugar with a ribose sugar at the 5' position. This product has been shown to be active against DNA and RNA viruses in the lab. It also has antiviral properties and can inhibit the synthesis of DNA, RNA, or both. The chemical structure of this product is novel and has not been found in nature.

    Fórmula:C10H11N5O2
    Pureza:Min. 95%
    Peso molecular:233.23 g/mol

    Ref: 3D-ALA82104

    25mg
    823,00€
    50mg
    1.241,00€
    100mg
    1.726,00€
  • 2'-Deoxy-5'-O-DMT-5-D-uridine 3'-CE phosphoramidite

    Produto Controlado

    2'-deoxy-5'-O-DMT-5-D-uridine 3'-CE phosphoramidite (2'DMTU) is a synthetic nucleoside with anticancer, antiviral and antiretroviral activity. 2'DMTU is a ribonucleotide monophosphate that can be used to modify RNA in the laboratory. It is a modified nucleoside that prevents RNA polymerase from adding onto the DNA strand and has been shown to activate apoptosis in cells that are resistant to anticancer drugs.
    Fórmula:C39H46N4O8PD
    Pureza:Min. 95%
    Peso molecular:731.81 g/mol

    Ref: 3D-PD08737

    100mg
    462,00€
    250mg
    657,00€
  • 2'-Methyl-guanosine-(iBu)-succinyl-CPG; 500 Å (RNA)


    2'-Methyl-guanosine-(iBu)-succinyl-CPG is a modified nucleoside with antiviral and anticancer properties. It is synthesized by the condensation of 2'-methyl-guanosine and succinic anhydride in the presence of tetrazole. The compound is a phosphoramidite, which is used as a building block for DNA synthesis.
    Pureza:Min. 95%

    Ref: 3D-NM11606

    250mg
    343,00€
    500mg
    490,00€
    1g
    781,00€
  • 3,5-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2-deoxyuridine

    CAS:
    3,5-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2-deoxyuridine is a novel modified monophosphate nucleoside. It is an antiviral agent and has been shown to have anticancer activity. 3,5-Di-o-acetyl-5-fluoro-O4-(2,4,6-trimethylphenyl)-2-deoxyuridine is synthesized by the reaction of 5'-triphosphates with 2'-deoxyribonucleosides in the presence of a phosphoramidite. This nucleoside has been found to be cytotoxic in vitro and in vivo against cancer cell lines and can be used as a therapeutic agent for the treatment of leukemia.
    Fórmula:C22H25FN2O7
    Pureza:Min. 95%
    Peso molecular:448.40 g/mol

    Ref: 3D-RFA12062

    5mg
    1.024,00€
    10mg
    1.343,00€
    25mg
    2.453,00€
    50mg
    3.924,00€
  • 5'-Deoxy-5'-iodo-2',3'-O-isopropylidene-5-chlorouridine

    CAS:

    5'-Deoxy-5'-iodo-2',3'-O-isopropylidene-5-chlorouridine is a novel antiviral agent that inhibits replication of viruses. It is synthesized from 5'-deoxy-5'-iodo-2',3'-O-isopropylideneuridine, which is then phosphorylated by the addition of a phosphate group. This compound has shown to be an activator in the synthesis of ribonucleosides and deoxyribonucleosides. The high purity and high quality of this compound make it suitable for use as a starting material for the synthesis of modified nucleosides for anticancer drugs.

    Fórmula:C12H14ClIN2O5
    Pureza:Min. 95%
    Peso molecular:428.61 g/mol

    Ref: 3D-ND16525

    50mg
    305,00€
    100mg
    336,00€
    250mg
    514,00€
    500mg
    883,00€
    1g
    1.515,00€
  • 2',3'-Dideoxycytidine-5'-triphosphate lithium salt - 100mM aqueous solution

    CAS:
    2',3'-Dideoxycytidine-5'-triphosphate lithium salt is a novel nucleoside, which can be used in the synthesis of oligonucleotides and DNA. The phosphoramidite is highly reactive and stable, and has been shown to have antiviral activity against influenza A virus. This chemical has also been shown to inhibit the growth of cancer cells by inhibiting DNA synthesis.
    Fórmula:C9H16N3O12P3
    Pureza:Min. 95%
    Peso molecular:451.16 g/mol

    Ref: 3D-ND32066

    1mg
    344,00€
    2mg
    489,00€
    5mg
    847,00€
    20mg
    2.352,00€
    50mg
    5.135,00€