Inibidores
Os inibidores são moléculas que se ligam a enzimas, receptores ou outras proteínas para reduzir ou bloquear sua atividade biológica. Esses compostos são amplamente utilizados em pesquisas para estudar vias biológicas, entender mecanismos de doenças e desenvolver medicamentos terapêuticos. Os inibidores desempenham um papel crucial no tratamento de várias doenças, incluindo câncer, doenças cardiovasculares e infecções. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento farmacêutico.
Subcategorias de "Inibidores"
- Angiogénese(2.786 produtos)
- Apoptose(6.265 produtos)
- Ciclo celular/Ponto de verificação(4.798 produtos)
- Cromatina/Epigenética(2.442 produtos)
- Sinalização Citoesquelética(1.530 produtos)
- Dano de DNA/Reparo de DNA(2.966 produtos)
- Endocrinologia/Hormónios(3.708 produtos)
- Enzima(3.669 produtos)
- GPCR/Proteína-G(9.018 produtos)
- Imunologia e Inflamação(3.883 produtos)
- Vírus da Influenza(301 produtos)
- Sinalização JAK/STAT(413 produtos)
- Sinalização MAPK(1.248 produtos)
- Transportador de Membranas/Canal Iónico(3.035 produtos)
- Metabolismo(10.214 produtos)
- Microbiologia/Virologia(7.604 produtos)
- Neurociência(10.384 produtos)
- Outros inibidores(36.027 produtos)
- Oxidação-Redução(42 produtos)
- Sinalização PI3K/Akt/mTOR(1.442 produtos)
- Proteases/Proteassoma(1.726 produtos)
- Células - tronco e Derivados(825 produtos)
- Tirosina Quinase/Adaptador(2.040 produtos)
- Ubiquitinação(1.718 produtos)
Exibir 16 mais subcategorias
Foram encontrados 66684 produtos de "Inibidores"
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AZD-4121 tert-butylammonium
CAS:AZD-4121 tert-butylammonium is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.Fórmula:C40H50F2N4O7SCor e Forma:SolidPeso molecular:768.91Thiolactomycin
CAS:Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).Fórmula:C11H14O2SPureza:98%Cor e Forma:SolidPeso molecular:210.29Encephalitic alphavirus-IN-1
Alphavirus-IN-1 blocks VEEV (EC50: 0.24 μM) & EEEV (EC50: 0.16 μM), non-toxic, stable in mice plasma.Fórmula:C27H25FN6O2Cor e Forma:SolidPeso molecular:484.52FCE-27262
CAS:FCE-27262 is a prostaglandin H2/thromboxane A2 receptor antagonist.Fórmula:C23H31N3O3Cor e Forma:SolidPeso molecular:397.51Axl-IN-3
Axl-IN-3 is a selective, potent and orally active inhibitor of AXL kinase (IC50: 41.5 nM) and has a low inhibitory effect on other kinases.Fórmula:C24H25ClN6O2Cor e Forma:SolidPeso molecular:464.95LY367385 hydrochloride
CAS:LY367385 hydrochloride: selective mGluR1a antagonist, IC50 = 8.8 μM, neuroprotective, anticonvulsant, antiepileptic.Fórmula:C10H12ClNO4Cor e Forma:SolidPeso molecular:245.66MDL-43291
CAS:MDL-43291 is a leukotriene receptor antagonist.Fórmula:C25H42O4SCor e Forma:SolidPeso molecular:438.66TIM-3-IN-1
TIM-3-IN-1 is a useful tool to enable further studies on the biology of TIM-3 immunoregulation in cancer.Fórmula:C20H16ClN7O3SCor e Forma:SolidPeso molecular:469.9Balanol
CAS:Balanol is an ATP-competitive Protein Kinase C and Protein Kinase A inhibitor.Fórmula:C28H26N2O10Cor e Forma:SolidPeso molecular:550.51Danavorexton
CAS:Danavorexton is an orexin receptor agonist.Fórmula:C21H32N2O5SCor e Forma:SolidPeso molecular:424.55EGFR-IN-45
EGFR-IN-45: Strong EGFR/CDK2 inhibitor (IC50s: 0.4 & 1.6 μM), halts cancer cell cycle pre-G1, prompts apoptosis, also targets Topo I/II.Fórmula:C28H23N7OCor e Forma:SolidPeso molecular:473.53BM635 hydrochloride (1493762-74-5 free base)
BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv).Fórmula:C25H30ClFN2OPureza:98%Cor e Forma:SolidPeso molecular:428.97CAII-IN-1
CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.Fórmula:C19H21FN4SCor e Forma:SolidPeso molecular:356.46Monoamine oxidase/Aromatase-IN-1
Compound 2q: Dual MAO/aromatase inhibitor; IC50: 39 nM (MAO-B), 31 nM (aromatase). Useful in neurological/breast cancer research.Fórmula:C19H19N3O3SCor e Forma:SolidPeso molecular:369.4412(S)-HEPE
CAS:12(S)-HEPE, made from EPA by 12-LO, is an anti-inflammatory ω-3 derivative affecting leukotriene formation.Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.45Thalicarpine
CAS:Thalicarpine, a natural anticancer alkaloid, inhibits p-glycoprotein and induces DNA damage, arresting cell cycle.Fórmula:C41H48N2O8Cor e Forma:SolidPeso molecular:696.83Cimpuciclib tosylate
CAS:Cimpuciclib tosylate, a selective CDK4 inhibitor (IC50: 0.49 nM), exhibits anti-tumor activity.Fórmula:C37H43FN8O4SCor e Forma:SolidPeso molecular:714.85Detoxin D1
CAS:Detoxin D1 is a selective blasticidin S antagonist.Fórmula:C28H41N3O8Pureza:98%Cor e Forma:SolidPeso molecular:547.642R,4R-Sacubitril
CAS:2R,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment of patients with heart failure.Fórmula:C24H29NO5Pureza:98%Cor e Forma:SolidPeso molecular:411.49TY 11345
CAS:TY 11345 is a proton pump inhibitor.Fórmula:C18H18N3NaO2SCor e Forma:SolidPeso molecular:363.41Tubulin polymerization-IN-9
CAS:Tubulin-IN-9 inhibits tubulin (IC50: 1.82 μM), halts K562 cells in G2/M, induces apoptosis, and has anti-cancer effects.Fórmula:C19H19NO5SeCor e Forma:SolidPeso molecular:420.32Sovesudil hydrochloride
Sovesudil (PHP-201) HCl: potent local ROCK inhibitor; targets ROCK I/II (IC50: 3.7/2.3 nM); lowers IOP, non-congesting.Fórmula:C23H23ClFN3O3Cor e Forma:SolidPeso molecular:443.9Dyrk1A/B-IN-1
Dyrk1A/B-IN-1 (3n) is a potent DYRK1A/B inhibitor, cell-permeable, with Ki values of 67.8 nM (1A) and 237.9 nM (1B), IC50s of 1.1 and 0.8 μM.Fórmula:C21H17N3O2S2Cor e Forma:SolidPeso molecular:407.51Gusperimus
CAS:Gusperimus was synthesized by chemical modification of spergualin and in combination with cyclosporine A to prevent diabetes in susceptible NOD mice.Fórmula:C17H37N7O3Cor e Forma:SolidPeso molecular:387.52Tenellin
CAS:Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.Fórmula:C21H23NO5Cor e Forma:SolidPeso molecular:369.41VEGFR-2/DHFR-IN-1
Compound 8b inhibits VEGFR-2/DHFR, combats various bacteria, and fights cancer cells.Fórmula:C20H18ClNO4Cor e Forma:SolidPeso molecular:371.8114,15-dehydro Leukotriene B4
CAS:LTB4 is a leukocyte-activating fatty acid via 5-lipoxygenase. Two receptors, BLT1 and BLT2, bind it. 14,15-dehydro LTB4 is a stronger BLT1 antagonist.Fórmula:C20H30O4Cor e Forma:SolidPeso molecular:334.45iNOS/PGE2-IN-1
iNOS/PGE2-IN-1: iNOS/PGE2 inhibitor, reduces LPS-induced NO, low ulcer risk, anti-inflammatory.Fórmula:C26H22ClN3O4Cor e Forma:SolidPeso molecular:475.9211-trans Leukotriene E4
CAS:Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum.Fórmula:C23H37NO5SCor e Forma:SolidPeso molecular:439.61TEI-9063
CAS:TEI-9063 is a stable and highly specific prostacyclin analogue of prostacyclin receptor in mast cell tumor p-815 cells.Fórmula:C23H38O4Cor e Forma:SolidPeso molecular:378.55SCH-900822
CAS:SCH-900822 is a potent and selective glucagon receptor antagonist.Fórmula:C34H43Cl2N7O2Cor e Forma:SolidPeso molecular:652.66GNTI TFA
CAS:GNTI TFA is a selective kappa opioid receptor antagonist.Fórmula:C31H31F6N5O7Cor e Forma:SolidPeso molecular:699.60Kalafungin
CAS:Kalafungin inhibits various fungi, yeasts, protozoa, and gram-positive bacteria, less so for gram-negative bacteria.Fórmula:C16H12O6Cor e Forma:SolidPeso molecular:300.26Esorubicin
CAS:Esorubicin, a doxorubicin derivative, intercalates DNA, inhibits topoisomerase II, has less cardiotoxicity, but more myelosuppression.Fórmula:C27H29NO10Cor e Forma:SolidPeso molecular:527.52IDO1-IN-14
IDO1-IN-14 is an IDO1 enzyme inhibitor with an IC50 of 396.9 nM and suppresses HeLa cell activity with an EC50 of 3393 nM.Fórmula:C18H12Cl2FN3O2Cor e Forma:SolidPeso molecular:392.21S1P1 agonist 4
CAS:S1P1 agonist 4 exhibits enhanced potency with an EC 50 value of less than 0.05 mg/kg and a predicted human half-life (t1/2) of approximately 5 days, indicatingFórmula:C24H31NO3Cor e Forma:SolidPeso molecular:381.51RAD51-IN-8
RAD51-IN-8 inhibits RAD51-BRCA2 interaction and H4A4 with EC50 of 19 μM; a micromolar PPI inhibitor.Fórmula:C16H14Cl2FN3O2Cor e Forma:SolidPeso molecular:370.21Meclocycline
CAS:Meclocycline: a tetracycline antibiotic, inhibits LDH, reduces cell toxicity from mutant huntingtin, doesn't change protein levels in PC12 cells.Fórmula:C22H21ClN2O8Cor e Forma:SolidPeso molecular:476.86(Rac)-Nebivolol
CAS:(Rac)-Nebivolol, a racemic β1-adrenergic blocker (IC50=0.8 nM), has vasodilatory properties and mitigates ethanol-induced cardiac harm.Fórmula:C22H25F2NO4Cor e Forma:SolidPeso molecular:405.43DSM705 hydrochloride
DSM705 hydrochloride: potent antimalarial, pyrrole-based DHODH inhibitor effective against Plasmodium, non-toxic to mammalian DHODH.Fórmula:C19H20ClF3N6OCor e Forma:SolidPeso molecular:440.85ATR-IN-19
CAS:ATR-IN-19 (Compound 15 R-configure) is an ATR inhibitor [1].Fórmula:C18H19N7OSCor e Forma:SolidPeso molecular:381.45G108
CAS:G108 is an inhibitor of human cGAS and is used in the study of autoimmune diseases associated with human cGAS.Fórmula:C16H14Cl2N4O2Pureza:99.13% - 99.75%Cor e Forma:SolidPeso molecular:365.21HIV-1 inhibitor-18
HIV-1 inhibitor-18 blocks HIV-1 capsid, effective on NL4-3 strain (EC50: 5.14 μM), slightly toxic (MT-4CC50>9.51).Fórmula:C27H31N3O6SCor e Forma:SolidPeso molecular:525.62L-I-OddU
CAS:L-I-OddU: Selective anti-EBV, halts virus DNA/protein synthesis. EC50: 0.03 µM, low toxicity (CC50: 1000 nM).Fórmula:C8H9IN2O5Cor e Forma:SolidPeso molecular:340.07TLN-232
CAS:TLN-232, a synthetic heptapeptide, may inhibit cancer by targeting M2PK to disrupt tumor cell energy production.Fórmula:C36H49N9O7S2Cor e Forma:SolidPeso molecular:783.96Cemdomespib
CAS:Cemdomespib (KU-596) is a potent Hsp90 modulator with neuroprotective effects and can improve diabetic neuropathy.Fórmula:C24H30FNO6Cor e Forma:SolidPeso molecular:447.5Aβ-IN-2
Aβ-IN-2 is a peptide inhibitor of Aβ1-42.Fórmula:C37H51NOCor e Forma:SolidPeso molecular:525.81MRTX-EX185
MRTX-EX185 inhibits GDP-KRAS/G12D; IC50=90 nM on G12D. It also binds GDP-HRAS.Fórmula:C33H33FN6O2Cor e Forma:SolidPeso molecular:564.65AChE-IN-22
AChE-IN-22 (10q) selectively inhibits AChE (IC50: 0.88 μM), less on BuChE (IC50: 10 μM), targets CAS and PAS, useful in Alzheimer's research.Fórmula:C21H20N4O5SCor e Forma:SolidPeso molecular:440.47MurB-IN-1
MurB-IN-1 (compound 44) inhibits key bacterial enzyme MurB with 3.57 μM affinity, offering treatment potential against P. aeruginosa.Fórmula:C12H7Cl2F3N2O2Cor e Forma:SolidPeso molecular:339.1Neuraminidase-IN-4
Neuraminidase-IN-4 inhibits neuraminidase (EC50: 1.59 μM) and has strong anti-H5N1 activity.Fórmula:C21H20N2O6SCor e Forma:SolidPeso molecular:428.46Miaosporone A
Miaosporone A: angucyclic quinone, cytotoxic to MCF-7, NCI-H187, Vero cells; anti-TB and anti-malaria with IC50 of 2.4 μM, 2.5 μM.Fórmula:C19H18O5Cor e Forma:SolidPeso molecular:326.34Chk1-IN-5
CAS:Chk1-IN-5 inhibits Chk1, blocking phosphorylation and suppressing colon cancer growth.Fórmula:C18H18FN7O2Cor e Forma:SolidPeso molecular:383.38Antitumor agent-75
Antitumor agent-75 is a novel and potent antitumor agent.Fórmula:C26H23FN6Cor e Forma:SolidPeso molecular:438.5Heme Oxygenase-1-IN-2
Heme Oxygenase-1-IN-2 is a novel inhibitor of heme oxygenase-1 (HO-1), displaying potent antiproliferative activity in vitro, with an IC50 value of 0.95 μM.Fórmula:C19H18ClN3OCor e Forma:SolidPeso molecular:339.82CFT8634
CAS:CFT8634 degrades BRD9, for synovial sarcoma and SMARCB1 tumor research, from patent WO2021178920A1.Fórmula:C37H45F3N6O5Cor e Forma:SolidPeso molecular:710.79NSD2-IN-1
CAS:NSD2-IN-1: potent, selective NSD2-PWWP1 inhibitor, IC50 0.11 μM, induces gene expression changes, apoptosis, cell cycle arrest.Fórmula:C29H31N5Cor e Forma:SolidPeso molecular:449.59SLC4101431
SLC4101431 is a potent SphK2 inhibitor with Ki value of 90 nM.Fórmula:C29H28ClN7OSCor e Forma:SolidPeso molecular:558.1BW-10
CAS:BW-10 potently inhibits bombesin evoked release of gastrointestinal hormones in vitro and in vivo.Fórmula:C57H72N14O8Cor e Forma:SolidPeso molecular:1081.27Antitumor agent-58
Antitumor agent-58 suppresses tumor growth, colony formation, cell migration, and induces mitochondrial dysfunction in MGC-803 cells.Fórmula:C27H28F3N9SCor e Forma:SolidPeso molecular:567.63CXCR2 antagonist 5
<p>CXCR2 antagonist 5 (compound 25) binds strongly (IC50=0.013μM) and mobilizes calcium (IC50=0.1μM).</p>Fórmula:C15H14F2N4O2SCor e Forma:SolidPeso molecular:352.36Dinalbuphine sebacate
CAS:Dinalbuphine sebacate: long-acting nalbuphine prodrug, μ-opioid partial agonist/antagonist, κ-opioid high-efficacy agonist.Fórmula:C52H68N2O10Cor e Forma:SolidPeso molecular:881.1G247
G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.Fórmula:C24H19Cl2FO3Cor e Forma:SolidPeso molecular:445.31EGFR/HER2/DHFR-IN-1
Potent EGFR/HER2/DHFR inhibitor for MCF-7 breast cancer; IC50: 0.153/0.108/0.291 μM; arrests G1/S phase, triggers apoptosis.Fórmula:C14H11BrN4O2SCor e Forma:SolidPeso molecular:379.23Ascofuranone
CAS:Ascofuranone is an inhibitor of the ubiquinol oxidase activity of Trypanosoma brucei mitochondrial alternative oxidase (TAO), as well as an inhibitor of HsDHODHFórmula:C23H29ClO5Cor e Forma:SolidPeso molecular:420.93hA3AR agonist 1
hA3AR agonist 1 is a potent human A 3 adenosine receptor (hA 3 AR) agonist (Ki = 2.40 nM) .Fórmula:C10H14N6OSCor e Forma:SolidPeso molecular:266.32CH5447240
CAS:CH5447240: potent hPTHR1 agonist, treats Hypoparathyroidism, EC50 12 nM, 55% oral bioavailability, raises rat serum calcium.Fórmula:C26H39N5O4SPureza:98%Cor e Forma:SolidPeso molecular:517.68COX-2/PI3K-IN-1
COX-2/PI3K-IN-1 (compound 5d) is a potent inhibitor of PI3K (IC50: 1.14 nM). COX-2/PI3K-IN-1 is a selective inhibitor of COX-2 (Ki: 3.24 nM).Fórmula:C19H14ClN5S2Cor e Forma:SolidPeso molecular:411.93FGFR-IN-6
CAS:FGFR-IN-6 (Compound 5) is an FGFR inhibitor.Fórmula:C23H22N6O3Cor e Forma:SolidPeso molecular:430.46Moflomycin
CAS:Moflomycin is an anthracycline derivative. It exhibits a higher antileukemic activity compared to other anthracyclines.Fórmula:C25H25IO10Pureza:98%Cor e Forma:SolidPeso molecular:612.36SAR-114137
CAS:SAR-114137 is a histone sphingomyelin kinase inhibitor used in the study of molluscum arteriosum and peripheral neuropathic pain.Fórmula:C25H34N4O7SPureza:99.09% - 99.91%Cor e Forma:SolidPeso molecular:534.63UK-370106
CAS:UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-Fórmula:C35H44N2O5Pureza:98%Cor e Forma:SolidPeso molecular:572.73Tacrolimus anhydrous 8-epimer
CAS:Tacrolimus anhydrous 8-epimer, an immunosuppressive l-pipecolic acid macrolide, blocks T cell growth by hindering IL-2.Fórmula:C44H69NO12Cor e Forma:SolidPeso molecular:804.02L5-DA
<p>L5-DA, a G-quadruplex ligand, stabilizes G4s in HeLa cells, induces apoptosis, and is cytotoxic with an IC50 of 4.3 μM.</p>Fórmula:C32H34N6O2Cor e Forma:SolidPeso molecular:534.65COX-2/NO-IN-1
COX-2/NO-IN-1: oral iNOS & NO blocker (IC50=3.52μM), COX-2 supressor, anti-inflammatory, protects kidneys.Fórmula:C15H15NO3Cor e Forma:SolidPeso molecular:257.28Vulolisib
CAS:Vulolisib inhibits PI3K (α: IC50 0.2nM, β: 168nM, γ: 90nM, δ: 49nM), taken orally with anti-cancer properties.Fórmula:C18H19F2N5O3SCor e Forma:SolidPeso molecular:423.44AChE/BChE-IN-3 hydrochloride
AChE/BChE-IN-3 (BMC-1) HCl is a dual inhibitor with IC50s: eqBChE 0.383 μM, elAChE 6.08 μM.Fórmula:C15H25ClN2O3Cor e Forma:SolidPeso molecular:316.82DNA crosslinker 3 dihydrochloride
CAS:Compound 1: a DNA minor groove binder with 1.4°C ΔTm; useful in cancer research.Fórmula:C15H22Cl2N8OCor e Forma:SolidPeso molecular:401.29LSD1-IN-17
LSD1-IN-17, a potent LSD1/CoREST/MAO inhibitor, IC50: 0.005/0.028/0.820 μM; hinders LNCaP prostate cancer cell growth, IC50: 17.2 μM.Fórmula:C20H18N2OSCor e Forma:SolidPeso molecular:334.43Resolvin D1 methyl ester
CAS:Resolvin D1, from docosahexaenoic acid via 15-/5-lipoxygenase, curbs acute inflammation; EC50 ~30 nM. Its methyl ester may enhance bioavailability.Fórmula:C23H34O5Cor e Forma:SolidPeso molecular:390.51Mibefradil dihydrochloride hydrate
CAS:Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.Fórmula:C29H42Cl2FN3O4Cor e Forma:SolidPeso molecular:586.57COX-2-IN-8
COX-2-IN-8 (Compound 6a) is a potent, selective, orally active COX-2 inhibitor (IC50: 6.585 μM) with a higher COX-2 selectivity than Celecoxib.Fórmula:C19H19N3O4S2Cor e Forma:SolidPeso molecular:417.5GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Fórmula:C28H32F3N5O4Cor e Forma:SolidPeso molecular:559.58FAPI-74
CAS:<p>FAPI-74 is a PET (positron emission tomography) tracer involved in early FAPI-PET imaging.FAPI-74 can be used to study cancer tumors and degenerative diseases.</p>Fórmula:C36H49N9O8Cor e Forma:SolidPeso molecular:735.83BMS 310705
CAS:BMS 310705, an Epothilone B analog, targets ovarian/renal/bladder/lung cancer, inducing apoptosis via mitochondria.Fórmula:C27H42N2O6SCor e Forma:SolidPeso molecular:522.70MC2652
MC2652, a potent LSD1 inhibitor, suppresses leukemia (MV4-11, NB4) and impedes prostate cancer (LNCaP) cell growth.Fórmula:C22H20N2OCor e Forma:SolidPeso molecular:328.41CARM1-IN-3 dihydrochloride
CARM1-IN-3 dihydrochloride (17b) is a potent CARM1 inhibitor (IC50: 0.07 μM) with selectivity over CARM3 (IC50 >25 μM).Fórmula:C24H34Cl2N4O2Cor e Forma:SolidPeso molecular:481.46PDE1-IN-4
PDE1-IN-4: inhibits PDE1C/A/B with IC50s 10/145/354 nM, may help study idiopathic pulmonary fibrosis.Fórmula:C33H33N3O4Cor e Forma:SolidPeso molecular:535.63MEIS-IN-1
CAS:<p>MEIS-IN-1 is a potent MEIS inhibitor that induces the expansion of hematopoietic stem cells in mice and humans.</p>Fórmula:C24H21F3N2O4Cor e Forma:SolidPeso molecular:458.43PD-1-IN-17 TFA
PD-1-IN-17 TFA is a potent PD-1 inhibitor, blocking 92% of splenocyte growth at 100 nM.Fórmula:C15H23F3N6O9Cor e Forma:SolidPeso molecular:488.37Elocalcitol
CAS:Elocalcitol is a calcitriol analog for inhibition of prostate cell growth.Fórmula:C29H43FO2Cor e Forma:SolidPeso molecular:442.65Topo I-IN-1
Topo I-IN-1 (14d) is a powerful Topo I inhibitor with antitumor effects and DNA intercalation, inducing apoptosis.Fórmula:C20H14BrN3O2Cor e Forma:SolidPeso molecular:408.25Gabaculine HCl
CAS:Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.Fórmula:C7H10ClNO2Cor e Forma:SolidPeso molecular:175.61AM-6494
CAS:AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).Fórmula:C22H21F2N5O3SPureza:98%Cor e Forma:SolidPeso molecular:473.5Antifungal agent 19
Antifungal agent 19 shows the potent antifungal activity ( EC 50 = 0.72 μM).Fórmula:C19H18F4O2Cor e Forma:SolidPeso molecular:354.34Tyk2-IN-3
CAS:Tyk2-IN-3 is an inhibitor of Tyk2 pseudokinase (IC50: 485 nM).Fórmula:C25H24N6O3S2Pureza:98%Cor e Forma:SolidPeso molecular:520.63NOS-IN-2
NOS-IN-2: potent, selective imidamide NOS inhibitor, IC50=20μM for iNOS, spares eNOS, low toxicity, useful in inflammation research.Fórmula:C18H20F3N3O2Cor e Forma:SolidPeso molecular:367.3715(R)-Lipoxin A4
CAS:<p>Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and</p>Fórmula:C20H32O5Cor e Forma:SolidPeso molecular:352.4714α-Demethylase/DNA Gyrase-IN-1
14α-Demethylase/DNA Gyrase-IN-1 (Compound 7c) is a potent inhibitor of 14α-Demethylase/DNA Gyrase with antibacterial activity.Fórmula:C26H22N4O4Cor e Forma:SolidPeso molecular:454.48
