Inibidores
Os inibidores são moléculas que se ligam a enzimas, receptores ou outras proteínas para reduzir ou bloquear sua atividade biológica. Esses compostos são amplamente utilizados em pesquisas para estudar vias biológicas, entender mecanismos de doenças e desenvolver medicamentos terapêuticos. Os inibidores desempenham um papel crucial no tratamento de várias doenças, incluindo câncer, doenças cardiovasculares e infecções. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento farmacêutico.
Subcategorias de "Inibidores"
- Angiogénese(2.687 produtos)
- Apoptose(6.097 produtos)
- Ciclo celular/Ponto de verificação(4.691 produtos)
- Cromatina/Epigenética(2.376 produtos)
- Sinalização Citoesquelética(1.472 produtos)
- Dano de DNA/Reparo de DNA(2.921 produtos)
- Endocrinologia/Hormónios(3.611 produtos)
- Enzima(3.655 produtos)
- GPCR/Proteína-G(8.755 produtos)
- Imunologia e Inflamação(3.765 produtos)
- Vírus da Influenza(298 produtos)
- Sinalização JAK/STAT(407 produtos)
- Sinalização MAPK(1.230 produtos)
- Transportador de Membranas/Canal Iónico(2.947 produtos)
- Metabolismo(9.940 produtos)
- Microbiologia/Virologia(7.347 produtos)
- Neurociência(10.240 produtos)
- Outros inibidores(36.533 produtos)
- Oxidação-Redução(43 produtos)
- Sinalização PI3K/Akt/mTOR(1.437 produtos)
- Proteases/Proteassoma(1.675 produtos)
- Células - tronco e Derivados(830 produtos)
- Tirosina Quinase/Adaptador(2.028 produtos)
- Ubiquitinação(1.682 produtos)
Exibir 16 mais subcategorias
Foram encontrados 66582 produtos de "Inibidores"
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Nonsteroidal aromatase inhibitor 1
Compound 13h, a nonsteroidal aromatase inhibitor, has a potent IC50 of 0.09 nM against CYP19A1, showing promise for breast cancer research.Fórmula:C22H16N4O2Cor e Forma:SolidPeso molecular:368.39Inupadenant HCl
CAS:<p>Inupadenant (EOS-850) is a selective A2a receptor antagonist, targeting immunosuppression in tumors.</p>Fórmula:C25H27ClF2N8O4S2Cor e Forma:SolidPeso molecular:641.11Tetrahydrouridine dihydrate
<p>THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.</p>Fórmula:C9H20N2O8Cor e Forma:SolidPeso molecular:284.26GABAA receptor agonist 1
Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.45AT1R antagonist 2
<p>AT1R antagonist 2 is a potent AT1R selective ligand with good AT1R affinity (Ki: 26 nM).</p>Fórmula:C29H37N5O4S2Cor e Forma:SolidPeso molecular:583.77Quinagolide hydrochloride
CAS:Quinagolide hydrochloride is a selective agonist of dopamine D2 receptor.Fórmula:C20H34ClN3O3SPureza:98%Cor e Forma:SolidPeso molecular:432.02AChE/BChE-IN-3 hydrochloride
<p>AChE/BChE-IN-3 (BMC-1) HCl is a dual inhibitor with IC50s: eqBChE 0.383 μM, elAChE 6.08 μM.</p>Fórmula:C15H25ClN2O3Cor e Forma:SolidPeso molecular:316.82AL-6556
CAS:<p>AL-6556 is a prostaglandin DP receptor agonist.</p>Fórmula:C20H33ClO5Cor e Forma:SolidPeso molecular:388.93IRAK4-IN-19
IRAK4-IN-19, an IRAK4 inhibitor (IC50: 4.3 nM), hampers IL23 synthesis and arthritis progression.Fórmula:C25H26F2N8OCor e Forma:SolidPeso molecular:492.52TAK-915
CAS:TAK-915: potent, brain-ready PDE2A inhibitor, 0.61 nM IC50, 4100x selectivity over PDE1A.Fórmula:C19H18F4N4O5Pureza:98%Cor e Forma:SolidPeso molecular:458.36Valbenazine tosylate
CAS:<p>Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying no</p>Fórmula:C38H54N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:762.97Antitrypanosomal agent 5
Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).Fórmula:C30H30N6O4SCor e Forma:SolidPeso molecular:570.66JTZ-951 HCl
CAS:JTZ-951 is a potent and orally active inhibitor of hypoxia inducible factor prolyl hydroxylase (PHD).Fórmula:C17H17ClN4O4Pureza:98%Cor e Forma:SolidPeso molecular:376.79GRPR antagonist-2
GRPR antagonist-2 blocks GRPR, kills some cancer cells, effective on HGC-27 (IC50: 0.77 μM) & Pan02 (IC50: 2.5 μM).Fórmula:C28H32F3N5O4Cor e Forma:SolidPeso molecular:559.58Thioquinapiperifil dihydrochloride
CAS:Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.Fórmula:C24H29ClN6OSPureza:99.81%Cor e Forma:SolidPeso molecular:485.05CD73-IN-7
CAS:<p>CD73-IN-7: potent inhibitor of CD73, blocks adenosine production to treat tumors.</p>Fórmula:C13H11ClN4O2Cor e Forma:SolidPeso molecular:290.7RU 52583
CAS:RU 52583 is an alpha 2-adrenergic receptor antagonist.Fórmula:C18H20N2Pureza:98%Cor e Forma:SolidPeso molecular:264.36Pisiferic acid
CAS:<p>Pisiferic acid is a novel PP2C activator and an an antimicrobial diterpenoid</p>Fórmula:C20H28O3Cor e Forma:SolidPeso molecular:316.43PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Fórmula:C18H20ClN3OSCor e Forma:SolidPeso molecular:361.89MRTX-EX185
<p>MRTX-EX185 inhibits GDP-KRAS/G12D; IC50=90 nM on G12D. It also binds GDP-HRAS.</p>Fórmula:C33H33FN6O2Cor e Forma:SolidPeso molecular:564.65SB 224289
CAS:SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.Fórmula:C32H32N4O3Pureza:98%Cor e Forma:SolidPeso molecular:520.62GG-43
GG-43 is a potent inhibitor of LIN28. The IC50 value of GG-43 against human LIN28A is 4 μM [1].Fórmula:C21H21NO3Cor e Forma:SolidPeso molecular:335.4α-Glucosidase-IN-18
α-Glucosidase-IN-18 (7B) is an orally active inhibitor of α-glucosidase, displaying an IC 50 value of 3.96 μM.Fórmula:C23H19NO2SCor e Forma:SolidPeso molecular:373.47MDL-43291
CAS:MDL-43291 is a leukotriene receptor antagonist.Fórmula:C25H42O4SCor e Forma:SolidPeso molecular:438.665-Iminodaunorubicin hydrochloride
CAS:<p>5-Iminodaunorubicin HCl: quinone-modified anthracycline with antitumor properties, induces DNA breaks in cancer cells.</p>Fórmula:C27H31ClN2O9Cor e Forma:SolidPeso molecular:563.00VU6005806
CAS:VU6005806 is a potent M4 PAM with EC50s: 94 nM (human), 28 nM (rat), 87 nM (dog), 68 nM (cyno); studied for neuropsychiatric disorders.Fórmula:C17H16F3N7O2SPureza:98%Cor e Forma:SolidPeso molecular:439.41Nrf2/HO-1 activator 2
Compound 13m, a difluoro derivative, activates Nrf2/HO-1, showing neuroprotective and antioxidant effects, useful in PD research.Fórmula:C20H16F2O5Cor e Forma:SolidPeso molecular:374.33TS010
TS010 is a highly potent inhibitor of GLO-I, with an IC50 value of 0.57 μM. It holds significant promise for advancements in cancer research [1].Fórmula:C16H12N4O4SCor e Forma:SolidPeso molecular:356.36PF-06462894
CAS:PF-06462894: morpholinopyrimidone, mGlu5 antagonist (Ki=6nM), no immune activation in mouse model.Fórmula:C18H23N3O3Pureza:98%Cor e Forma:SolidPeso molecular:329.39Lorajmine
CAS:Lorajmine, a monochloroacetyl derivative of ajmaline, is a class Ia antiarrhythmic agent that is rapidly hydrolyzed to ajmaline by plasma and tissue esterases.Fórmula:C22H27ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:402.911,9-Dideoxyforskolin
CAS:The compound is an inactive analog of forskolin(an adenylyl cyclase activator).Fórmula:C22H34O5Pureza:98%Cor e Forma:SolidPeso molecular:378.5KR-67607
CAS:KR-67607, or NTX-101, is a novel 11β-HSD1 inhibitor that protects against eye injury by reducing cortisol and preserving eye structures.Fórmula:C24H29Cl2F3N4O4SCor e Forma:SolidPeso molecular:597.48SCP1-IN-2
<p>SCP1-IN-2: potent, selective SCP1 inhibitor; induces REST degradation, hinders its activity, may study REST-driven glioblastoma growth.</p>Fórmula:C19H17F3N2O6S2Cor e Forma:SolidPeso molecular:490.47MDK-3298
CAS:MDK-3298 is a reversible covalent inhibitor of Mcl-1, a target of protein-protein interaction (PPI).Fórmula:C35H32BN3O7Pureza:98%Cor e Forma:SolidPeso molecular:617.46AR antagonist 4
<p>AR antagonist 4 (Compound 67-b) is an orally active androgen receptor (AR) antagonist that acts on wild-type AR (IC50: 246.6 nM).</p>Fórmula:C29H36N4OCor e Forma:SolidPeso molecular:456.62Antitumor agent-48
Antitumor agent-48, a 2,3-dehydrosilybin derivative, exhibits cytotoxicity on MCF-7, NCI-H1299, HepG2, HT29 cells; IC50 ranging 8.06-16.51 µM.Fórmula:C35H34N2O14Cor e Forma:SolidPeso molecular:706.65Topoisomerase I/II inhibitor 3
<p>Topoisomerase I/II inhibitor 3 suppresses cell growth and induces apoptosis in liver cancer by blocking PI3K/Akt/mTOR.</p>Fórmula:C24H24N2O4Cor e Forma:SolidPeso molecular:404.46FAK-IN-6
<p>FAK-IN-6: Potent FAK inhibitor (IC50=1.415 nM), anti-cancer, for pancreatic studies.</p>Fórmula:C25H31ClN5O6PSCor e Forma:SolidPeso molecular:596.04AM8936
AM8936: potent CB1 agonist, EC50 rCB1=8.6nM/hCB1=1.4nM, Ki rat CB1=0.55nM; potential for CNS, metabolic, pain, glaucoma research.Fórmula:C25H33NO3Cor e Forma:SolidPeso molecular:395.53Befiradol hydrochloride
CAS:<p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>Fórmula:C20H23Cl2F2N3OPureza:99.1%Cor e Forma:SolidPeso molecular:430.32Encephalitic alphavirus-IN-1
Alphavirus-IN-1 blocks VEEV (EC50: 0.24 μM) & EEEV (EC50: 0.16 μM), non-toxic, stable in mice plasma.Fórmula:C27H25FN6O2Cor e Forma:SolidPeso molecular:484.52EP-7041 HCl
CAS:EP-7041 is a novel, potent, and selective Factor XIa inhibitor.Fórmula:C19H27ClN4O4Cor e Forma:SolidPeso molecular:410.89BI 703704
CAS:<p>BI 703704, a soluble guanylate cyclase (sGC) activator, inhibits the progression of diabetic nephropathy in the ZSF1 rat [1].</p>Fórmula:C32H37N3O4SPureza:98%Cor e Forma:SolidPeso molecular:559.72PI3kδ inhibitor 1
CAS:<p>PI3kδ inhibitor 1 is a selective inhibitor of PI3Kδ (IC50 of 3.8 nM).</p>Fórmula:C28H33FN6O2Pureza:98%Cor e Forma:SolidPeso molecular:504.60PDHK-IN-5
<p>PDHK-IN-5, potent PDHK2 (0.006 μM IC50) & PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.</p>Fórmula:C30H31N5O2Cor e Forma:SolidPeso molecular:493.6PF-03715455
CAS:PF-03715455 is a potent p38 MAPK inhibitor, reducing TNFα in blood (IC50=1.7 nM) with selectivity for p38α, and may treat COPD.Fórmula:C35H34ClN7O3S2Pureza:98%Cor e Forma:SolidPeso molecular:700.27MsbA-IN-1
MsbA-IN-1: Potent MsbA inhibitor (IC50: 4 nM), anti-E. coli (MIC: 79 μM), penetrates Gram-negative bacteria.Fórmula:C23H18Cl2FNO3Cor e Forma:SolidPeso molecular:446.3LasR-IN-3
LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.Fórmula:C22H19N3O2Cor e Forma:SolidPeso molecular:357.41COX-2-IN-29
<p>COX-2-IN-29 is a selective inhibitor of orally active COX-2 (IC50: 0.005 μM).</p>Fórmula:C22H23FN2O6S2Cor e Forma:SolidPeso molecular:494.56Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Fórmula:C26H26FN3O4Cor e Forma:SolidPeso molecular:463.5Tandutinib (MLN518) HCl
Tandutinib antagonizes FLT3, PDGFR, and c-Kit with an IC50 of ~200 nM.Fórmula:C31H43ClN6O4Pureza:98%Cor e Forma:SolidPeso molecular:599.16Antiproliferative agent-3
Antiproliferative agent-3 (comp 4) exhibits potent growth inhibitory effects against MCF-7 cells with IC 50 of 0.19 nM [1].Fórmula:C11H12N2O5SCor e Forma:SolidPeso molecular:284.29L 731735
CAS:L 731735 is a farnesyltransferase inhibitor.Fórmula:C19H40N4O4SPureza:98%Cor e Forma:SolidPeso molecular:420.61L2H2-6OTD
CAS:L2H2-6OTD is a telomerase inhibitor with G-quadruplex loops; IC50: 15 nM.Fórmula:C30H30N10O8Cor e Forma:SolidPeso molecular:658.62Anti-inflammatory agent 13
Pentacyclic triterpene, Anti-inflammatory 13 inhibits DAMP/PAMP inflammation models.Fórmula:C30H48O4Cor e Forma:SolidPeso molecular:472.7GLS1 Inhibitor-5
<p>GLS1 Inhibitor-5 (24y): Selective, oral glutaminase 1 inhibitor; IC50 68 nM; induces apoptosis; anti-tumor.</p>Cor e Forma:Solid15(R)-Lipoxin A4
CAS:<p>Lipid-derived lipoxins are produced at the site of vascular and mucosal inflammation where they down-regulate polymorphonuclear leukocyte recruitment and</p>Fórmula:C20H32O5Cor e Forma:SolidPeso molecular:352.47Tubulin polymerization-IN-9
CAS:Tubulin-IN-9 inhibits tubulin (IC50: 1.82 μM), halts K562 cells in G2/M, induces apoptosis, and has anti-cancer effects.Fórmula:C19H19NO5SeCor e Forma:SolidPeso molecular:420.32ETP-47037
CAS:ETP-47037: strong PI3Kα inhibitor (IC50: 0.99 nM), also targets PI3Kβ, δ, γ; may protect telomeres.Fórmula:C20H27N9O3SCor e Forma:SolidPeso molecular:473.55Tubulin polymerization-IN-4
CAS:Tubulin polymerization-IN-4: inhibits tubulin (IC50=4.6 μM), blocks G2/M phase, induces apoptosis, hinders cell cloning/migration, damages vasculature.Fórmula:C21H21ClN2O4Cor e Forma:SolidPeso molecular:400.86PI3K-IN-27
CAS:PI3K-IN-27 is a potent PI3K inhibitor, relevant for cancer and immune disease research. See patent WO2021233227A1.Fórmula:C30H26F2N6O2SCor e Forma:SolidPeso molecular:572.63Aurora inhibitor 1
CAS:<p>Aurora inhibitor 1 is a potent Aurora inhibitor (IC50: ≤ 4 nM and ≤13 nM for Aurora A and Aurora B kinase).</p>Fórmula:C23H25N9SPureza:98%Cor e Forma:SolidPeso molecular:459.57Kinamycin B
CAS:Kinamycin B is an antibacterial agent with anticancer activity.Fórmula:C20H16N2O8Pureza:98%Cor e Forma:SolidPeso molecular:412.35K-14585
CAS:<p>K-14585 blocks PAR(2), reduces NFkappaB activity, and IL-8 response, but alone can boost IL-8.</p>Fórmula:C51H56Cl2N8O4Cor e Forma:SolidPeso molecular:915.95L 734217
CAS:L 734217 is an antagonist of the fibrinogen receptor.Fórmula:C18H31N3O4Pureza:98%Cor e Forma:SolidPeso molecular:353.46S-HP210
S-HP210: selective GR modulator, blocks NF-κB (IC50: 1.92 μM), non-toxic to mouse fibroblasts.Fórmula:C22H19N3O2S2Cor e Forma:SolidPeso molecular:421.54FLT3/ITD-IN-1
<p>FLT3/ITD-IN-1 inhibits FLT3-ITD with IC50s: 38.2 nM (FLT3) and 144.1 nM (ITD), and fights acute myeloid leukemia.</p>Fórmula:C19H22N6O2Cor e Forma:SolidPeso molecular:366.42Naldemedine tosylate
CAS:<p>Naldemedine (S-297995) tosylate, a PAMORA, targets μ-, δ-, κ-opioid receptors, aiding OIC research, may bind to SARS-CoV2's 3CL pro.</p>Fórmula:C39H42N4O9SCor e Forma:SolidPeso molecular:742.84MetRS-IN-1
CAS:MetRS-IN-1 (Compound 27) is an inhibitor of E. coli methionyl-tRNA synthetase (MetRS) with an IC50 value of 237 nM [1].Fórmula:C15H13N3O4SCor e Forma:SolidPeso molecular:331.35S1PR1 agonist 2
CAS:S1PR1 agonist 2 is potent for autoimmune research (from WO2021175225A1).Fórmula:C25H25N5O4Cor e Forma:SolidPeso molecular:459.50Demethoxyviridin
CAS:<p>Demethoxyviridin inhibits mammalian Ptdlns 3-kinase (p110) and is antifungal.</p>Fórmula:C19H14O5Pureza:98%Cor e Forma:SolidPeso molecular:322.31DBCO-SS-PEG4-Biotin
DBCO-SS-PEG4-Biotin: cleavable ADC linker with 4-unit PEG, used in ADC synthesis.Fórmula:C45H62N6O9S3Pureza:98%Cor e Forma:SolidPeso molecular:927.2KIRA9
KIRA9 inhibits IRE1 with a 4.8 μM IC50, blocking ER-stress-induced mRNA decay and apoptosis by fully binding IRE1's ATP site.Fórmula:C27H27F3N6O3SCor e Forma:SolidPeso molecular:572.6Antifungal agent 16
<p>Antifungal agent 16 has antimicrobial activity comparable to that of ciprofloxacin and has higher antifungal activity than fluconazole.</p>Fórmula:C27H21N5O2SCor e Forma:SolidPeso molecular:479.55M-525
CAS:M-525, a potent first-in-class menin-MLL inhibitor, binds at 3 nM IC50 and curbs MLL leukemia cell growth & gene expression.Fórmula:C39H51FN6O5SPureza:98%Cor e Forma:SolidPeso molecular:734.92RAD51-IN-6
CAS:RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)Fórmula:C27H40N3O5PSCor e Forma:SolidPeso molecular:549.66Aβ-IN-2
<p>Aβ-IN-2 is a peptide inhibitor of Aβ1-42.</p>Fórmula:C37H51NOCor e Forma:SolidPeso molecular:525.81PF 03709270
CAS:PF 03709270 is an oral prodrug of sulopenem with broad-spectrum antibacterial effects on gram-positive and gram-negative bacteria.Fórmula:C19H27NO7S3Pureza:98%Cor e Forma:SolidPeso molecular:477.61MtTMPK-IN-1
MtTMPK-IN-1 inhibits MtTMPK with 2.5 μM IC50, shows moderate anti-tuberculosis activity, and is low in cytotoxicity.Fórmula:C22H24N4O3Cor e Forma:SolidPeso molecular:392.45Cimpuciclib tosylate
CAS:Cimpuciclib tosylate, a selective CDK4 inhibitor (IC50: 0.49 nM), exhibits anti-tumor activity.Fórmula:C37H43FN8O4SCor e Forma:SolidPeso molecular:714.85NITD-688
CAS:NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.Fórmula:C25H32N4O3S2Cor e Forma:SolidPeso molecular:500.68Ivaltinostat formic
Ivaltinostat (CG-200745) is an oral panHDAC inhibitor, inducing apoptosis and enhancing cancer drug sensitivity.Fórmula:C25H35N3O6Cor e Forma:SolidPeso molecular:473.56CBP/p300-IN-18
CBP/p300-IN-18 (compound 8) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.056 μM) and LK2 H3K27 (IC50: 0.46 μM).Fórmula:C25H27FN4O3Cor e Forma:SolidPeso molecular:450.51Cilobamine mesylate
CAS:Cilobamine mesylate is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.Fórmula:C18H27Cl2NO4SCor e Forma:SolidPeso molecular:424.38ZM514
<p>ZM514 inhibits CD73 (hCD73 IC50: 1.39 μM, mCD73 IC50: 14.65 μM) with low cytotoxicity, suitable for cancer research.</p>Fórmula:C36H57NO4Cor e Forma:SolidPeso molecular:567.84Antibacterial agent 81
CAS:Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.Fórmula:C33H28N2O8Cor e Forma:SolidPeso molecular:580.58NI-Pano
NI-Pano (CH-03) is a novel hypoxia-activated KDAC inhibitor capable of O2-dependent release of the compound panobinostat.Fórmula:C26H28N6O4Cor e Forma:SolidPeso molecular:488.54SARS-CoV-2-IN-23
SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].Fórmula:C21H22N2OCor e Forma:SolidPeso molecular:318.41IAB15
CAS:IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].Fórmula:C15H14F3NO2Cor e Forma:SolidPeso molecular:297.27KRAS inhibitor-13
CAS:KRAS inhibitor-13 blocks KRAS G12C (IC50: 0.883 μM) and p-ERK in some cancer cells; promising for pancreatic, colorectal, lung cancer research.Fórmula:C25H19ClFN3O2SCor e Forma:SolidPeso molecular:479.95EGFR-IN-62
EGFR-IN-62: IC50 of 10-242 nM for various EGFR mutations, blocks A549/H1975 cell cycle, induces apoptosis, and inhibits cell motility and proliferation.Fórmula:C30H33N9O2Cor e Forma:SolidPeso molecular:551.64J-113397
CAS:J-113397 is a potent and selective NOP receptor antagonist (IC50 = 2.3 nM).Fórmula:C24H37N3O2Pureza:98%Cor e Forma:SolidPeso molecular:399.57LSD1/ER-IN-1
LSD1/ER-IN-1 inhibits ER & LSD1 (IC50: 1.55 μM), and fights MCF-7 breast cancer (IC50: 8.79 μM).Fórmula:C23H18FNO6SCor e Forma:SolidPeso molecular:455.46PSB 36
CAS:A1 adenosine receptor antagonistFórmula:C21H30N4O3Pureza:98%Cor e Forma:SolidPeso molecular:386.49Emd 52297
CAS:<p>Emd 52297 is an inhibitor of renin.</p>Fórmula:C39H59N11O7Pureza:98%Cor e Forma:SolidPeso molecular:793.96HDAC8-IN-2
<p>HDAC8-IN-2 (5o) inhibits both smHDAC8 and hHDAC8 with IC50s of 0.27 μM, 0.32 μM, kills schistosome larvae, and lowers egg laying.</p>Fórmula:C21H16N2O5Cor e Forma:SolidPeso molecular:376.36CHK1-IN-4
CAS:<p>CHK1-IN-4 is a potent inhibitor of checkpoint kinase 1 (chk1) and potently inhibits chk1 phosphorylation in the tumor cells with anti-tumor activity.</p>Fórmula:C18H18BrN7O2Pureza:98%Cor e Forma:SolidPeso molecular:444.29Purine phosphoribosyltransferase-IN-1
Compound (S,R)-48 inhibits Pf, Pv, & Tbr PRT with Ki of 50, 20, 2 nM.Fórmula:C11H15N5Na4O10P2Cor e Forma:SolidPeso molecular:531.17Thiolactomycin
CAS:Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).Fórmula:C11H14O2SPureza:98%Cor e Forma:SolidPeso molecular:210.29Flutimide
CAS:Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.Fórmula:C12H18N2O3Cor e Forma:SolidPeso molecular:238.28
