Inibidores
Os inibidores são moléculas que se ligam a enzimas, receptores ou outras proteínas para reduzir ou bloquear sua atividade biológica. Esses compostos são amplamente utilizados em pesquisas para estudar vias biológicas, entender mecanismos de doenças e desenvolver medicamentos terapêuticos. Os inibidores desempenham um papel crucial no tratamento de várias doenças, incluindo câncer, doenças cardiovasculares e infecções. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento farmacêutico.
Subcategorias de "Inibidores"
- Angiogénese(2.797 produtos)
- Apoptose(6.275 produtos)
- Ciclo celular/Ponto de verificação(4.805 produtos)
- Cromatina/Epigenética(2.462 produtos)
- Sinalização Citoesquelética(1.534 produtos)
- Dano de DNA/Reparo de DNA(2.959 produtos)
- Endocrinologia/Hormónios(3.708 produtos)
- Enzima(3.670 produtos)
- GPCR/Proteína-G(9.020 produtos)
- Imunologia e Inflamação(3.884 produtos)
- Vírus da Influenza(301 produtos)
- Sinalização JAK/STAT(414 produtos)
- Sinalização MAPK(1.249 produtos)
- Transportador de Membranas/Canal Iónico(3.050 produtos)
- Metabolismo(10.206 produtos)
- Microbiologia/Virologia(7.612 produtos)
- Neurociência(10.379 produtos)
- Outros inibidores(36.012 produtos)
- Oxidação-Redução(42 produtos)
- Sinalização PI3K/Akt/mTOR(1.442 produtos)
- Proteases/Proteassoma(1.724 produtos)
- Células - tronco e Derivados(819 produtos)
- Tirosina Quinase/Adaptador(2.035 produtos)
- Ubiquitinação(1.718 produtos)
Exibir 16 mais subcategorias
Foram encontrados 66683 produtos de "Inibidores"
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HIV-IN-3
HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.Fórmula:C21H32ClN7O3Cor e Forma:SolidPeso molecular:465.98CEP-7055
CAS:CEP-18770: oral proteasome inhibitor; blocks NF-kappaB; may cause cancer cell apoptosis; less toxic than bortezomib in normal cells.Fórmula:C32H35N3O4Cor e Forma:SolidPeso molecular:525.64Alkannin
CAS:Alkannin: potent, tumor-specific PKM2 inhibitor; non-inhibitory to PKM1/PKL; potential anticancer agent.Fórmula:C16H16O5Cor e Forma:SolidPeso molecular:288.3Steroid sulfatase-IN-4
Steroid sulfatase-IN-4 irreversibly inhibits human STS with a 25 nM IC50, useful for endometriosis research.Fórmula:C19H17ClN2O5SCor e Forma:SolidPeso molecular:420.87Chitin synthase inhibitor 8
Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infectionsFórmula:C23H23N3O5Cor e Forma:SolidPeso molecular:421.45STAT3-IN-7
CAS:STAT3-IN-7, an orally active aryl sulfonamido azetidine compound, serves as a STAT3 inhibitor with anticancer activities.Fórmula:C30H26F5N5O4SCor e Forma:SolidPeso molecular:647.62MRS4458
CAS:MRS4458 is an effective inhibitor of the P2Y14 Receptor.Fórmula:C24H20F3N5O3SPureza:98%Cor e Forma:SolidPeso molecular:515.51ODN 2088
CAS:ODN 2088 is a potent inhibitor of TLR3, TLR7 and TLR9 that is non-cytotoxic and shows inhibition of the release of IFN-α and IL-6.Cor e Forma:SolidODN 21158
CAS:<p>ODN 21158 is a potent, non-cytotoxic inhibitor of G-modified TLR3 and TLR9. ODN 21158 dose-dependently inhibits IFN-α secretion.</p>Cor e Forma:SolidBMS-066
CAS:BMS-066 is an IKKβ/Tyk2 pseudokinase inhibitor. With IC50s of 9 nM and 72 nM, respectively.Fórmula:C19H21N7O2Pureza:98%Cor e Forma:SolidPeso molecular:379.42Fonadelpar
CAS:Fonadelpar is an agonist of PPARδ. It also is used in the research of neuroparalytic keratopathy.Fórmula:C25H23F3N2O4SPureza:98%Cor e Forma:SolidPeso molecular:504.52BAY-3153
CAS:BAY-3153 is a selective CCR1 ( C-C motif chemokine receptor 1 ) antagonist (human IC 50 =3 nM ; rat IC 50 =11 nM ; mice IC 50 =81 nM) .Fórmula:C25H29Cl2N3O4Cor e Forma:SolidPeso molecular:506.42nNOS-IN-25
CAS:nNOS-IN-25 is an effective, selective, and cell-permeable inhibitor of neuronal nitric oxide synthase.Fórmula:C21H22N4Pureza:98%Cor e Forma:SolidPeso molecular:330.43DAD dichloride
DAD dichloride is a 3rd-gen photoelectric switch, blocks K+ channels, and helps in visual function research.Fórmula:C26H42Cl2N6OCor e Forma:SolidPeso molecular:525.56Calphostin I
CAS:Calphostins, from Cladosporium fungus, inhibit PKC. Notably, calphostin C is a potent biochemical tool.Fórmula:C44H38O15Cor e Forma:SolidPeso molecular:806.76LY 245769
CAS:LY 245769 is an inhibitor of leukotriene E4 (LTE4).Fórmula:C25H33F3N8OSPureza:98%Cor e Forma:SolidPeso molecular:550.6411-trans Leukotriene E4
CAS:Slow isomerization of the C-11 double bond of LTE4 leads to the formation of 11-trans LTE4. 11-trans LTE4 is equipotent to LTE4 in contracting guinea pig ileum.Fórmula:C23H37NO5SCor e Forma:SolidPeso molecular:439.61OP-5244
CAS:OP-5244 has comparable potency to bisphosphonic acid series and targets CD73.Fórmula:C19H29ClN5O9PPureza:98%Cor e Forma:SolidPeso molecular:537.89Antifungal agent 25
Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.Cor e Forma:SolidUNC7467
CAS:UNC7467, potent IP6K2/1/6 inhibitor (4.9/8.9/1320 nM); lowers inositol pyrophosphates, minimal impact on other inositol phosphates; for obesity research.Fórmula:C20H13NO3Pureza:98.28% - 98.64%Cor e Forma:SoildPeso molecular:315.32NU5455
CAS:NU5455 is a potent DNA-PKcs inhibitor, oral, boosts doxorubicin in liver tumors, amplifies topoisomerase inhibitors, no adverse effects.Fórmula:C34H33N3O5SCor e Forma:SolidPeso molecular:595.71Guraxetan
Guraxetan can be used in the synthesis of the antitumour drug Lutetium (177Lu) zadavotide Guraxetan.Fórmula:C20H34N4O9Cor e Forma:SolidPeso molecular:474.51Avorelin acetate
CAS:Avorelin acetate is a luteinizing hormone releasing hormone (LH-RH) agonist.Fórmula:C67H89N17O14Cor e Forma:SolidPeso molecular:1356.55Leukotriene F4
CAS:LTF4, made in vitro from LTE4 with enzymes, contracts vascular muscle weakly; potency is LTD4 > LTC4 > LTE4 >> LTF4.Fórmula:C28H44N2O8SCor e Forma:SolidPeso molecular:568.72(R)-BAY-899
(R)-BAY-899: R-isomer, selective LH-R antagonist, effective on hLH (IC50: 185 nM) and rLH (IC50: 46 nM), orally active.Fórmula:C25H19F2N5O2Cor e Forma:SolidPeso molecular:459.45GL0388
GL0388, a Bax activator, induces apoptosis, hinders breast cancer growth, and has IC50 of 0.299-1.57 μM.Fórmula:C21H17FN2OCor e Forma:SolidPeso molecular:332.37PI4KIIIbeta-IN-11
CAS:PI4KIIIbeta-IN-11 is a PI4KIIIβ inhibitor (mean pIC50=9.1) that can be used to study diseases caused by RNA viruses and Plasmodium falciparum.Fórmula:C33H39N7O3Cor e Forma:SolidPeso molecular:581.71BACE1-IN-4
CAS:BACE1-IN-4 is a potent and highly selective BACE1 inhibitor (IC50: 3.8 nM; Ki: 1.9 nM), more selective at BACE1 over BACE2.Fórmula:C21H23F2N5O4S2Pureza:98%Cor e Forma:SolidPeso molecular:511.57Lipoxin A5
CAS:LXA5 is made from EPA by leukocytes, contracts guinea pig lungs like LXA4/LXB4, but doesn't dilate aorta.Fórmula:C20H30O5Cor e Forma:SolidPeso molecular:350.45GSK 366
CAS:GSK 366 is a potent kynurenine-3-monooxygenase (KMO) inhibitor (IC50s: 0.7 nM and 2.3 nM for P. fluorescens-KMO and human KMO).Fórmula:C17H16ClN3O4Pureza:98%Cor e Forma:SolidPeso molecular:361.78Antitumor agent-43
Antitumor agent-43 (Compound 4B) is a potent antitumor agent that induces cell cycle arrest at G2/M phase.Fórmula:C16H8N2O3Cor e Forma:SolidPeso molecular:276.25ABT 491 Hydrochloride
CAS:ABT-491 hydrochloride is an active platelet activator receptor (PAF-R) antagonist with good selectivity and oral administration.Fórmula:C28H23ClFN5O2Cor e Forma:SolidPeso molecular:515.97KFA1982
CAS:KFA1982 is a novel and potent factor Xa inhibitor.Fórmula:C28H34ClN3O9S2Cor e Forma:SolidPeso molecular:656.17YW3-56
CAS:YW3-56 is a potent peptidylarginine deiminase (PAD) inhibitor, with an IC50 of 1-5 μM for PAD4.Fórmula:C27H32ClN5O2Cor e Forma:SolidPeso molecular:494.03YM-60828 dihydrochloride
CAS:YM-60828 dihydrochloride is a Factor Xa (FXa) inhibitor and anticoagulant used in the treatment of venous thromboembolic disease.Fórmula:C27H33Cl2N5O5SCor e Forma:SolidPeso molecular:610.55Antibacterial agent 112
Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.Fórmula:C35H23N5O5Cor e Forma:SolidPeso molecular:593.59BM635 hydrochloride
BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.Fórmula:C25H30ClFN2OCor e Forma:SolidPeso molecular:428.97Adafosbuvir
CAS:Adafosbuvir has antiviral activity.Fórmula:C22H29FN3O10PCor e Forma:SolidPeso molecular:545.457RN941
CAS:RN941 is a highly potent Bruton's tyrosine kinase (BTK) inhibitor.Fórmula:C34H34FN7O5Pureza:98%Cor e Forma:SolidPeso molecular:639.68SP-471
SP-471 is a potent inhibitor of dengue virus (DENV) protease (IC50: 18 μM) and inhibits the inter- and intramolecular protease processes of DENV.Fórmula:C33H26BrN5Cor e Forma:SolidPeso molecular:572.5NTU281
CAS:NTU281 inhibits transglutaminase-2, lowers creatinine in diabetic rats, reduces proteinuria, and fights glomerulosclerosis.Fórmula:C25H31N2O6SCor e Forma:SolidPeso molecular:487.59KDOAM-25 citrate
CAS:KDOAM-25 citrate inhibits KDM5A/B/C/D (IC50: 71, 19, 69, 69 nM); boosts H3K4 methylation, hinders MM1S cell growth. [1]Fórmula:C21H33N5O9Pureza:98%Cor e Forma:SolidPeso molecular:499.51Riminkefon
CAS:Riminkefon is a kappa opioid receptor agonist .Fórmula:C38H57N7O6Cor e Forma:SolidPeso molecular:707.9KRAS G12D inhibitor 3
CAS:KRAS G12D Inhibitor 3, a compound targeting the KRAS G12D mutation, demonstrates potent antitumor efficacy with an inhibitory concentration (IC50) of less thanFórmula:C34H31ClF3N5O2Cor e Forma:SolidPeso molecular:634.09Antibiotic MA 144M1
CAS:Antibiotic MA 144M1, an anthracycline, targets gram-positive bacteria and animal tumors; derived from Streptomyces fermentation or aclacinomycin A conversion.Fórmula:C42H55NO15Cor e Forma:SolidPeso molecular:813.88SARS 3CLpro-IN-1
CAS:SARS 3CLpro-IN-1: stereospecific SARS 3CL protease inhibitor, octahydroisochromene class, IC50 = 95 μM.Fórmula:C22H38N4O2Cor e Forma:SolidPeso molecular:390.56KH-259
KH-259: potent, selective CNS-penetrant HDAC6 inhibitor with 0.26 μM IC50; shows antidepressant effects in mice.Fórmula:C20H25N3O2Cor e Forma:SolidPeso molecular:339.43BPN-15606 besylate
BPN-15606 besylate is a potent oral γ-secretase regulator reducing Aβ42 and Aβ40 with good pharmacokinetics. IC50: 7 nM (Aβ42), 17 nM (Aβ40).Fórmula:C29H29FN6O4SCor e Forma:SolidPeso molecular:576.64JAK-2/3-IN-3
JAK-2-/3-IN-3 (ST4j) is a potent JAK2/3 inhibitor for leukemia research, with IC50s: JAK2, 13 nM; JAK3, 14.86 nM; induces apoptosis.Fórmula:C13H10Cl2N4O2Cor e Forma:SolidPeso molecular:325.15YK5
CAS:YK5 is an allosteric inhibitor pocket of Hsp70 and represents a previously unknown chemical tool to investigate cellular mechanisms associated with Hsp70.Fórmula:C18H24N8O3SPureza:98%Cor e Forma:SolidPeso molecular:432.508-Deazafolic acid
CAS:8-Deazafolic acid inhibits folate-dependent bacteria S. faecium & L. casei, and fights lymphoid leukemia L1210 in mice.Fórmula:C20H20N6O6Pureza:98%Cor e Forma:SolidPeso molecular:440.41D4R antagonist-1
Potent, selective D4R antagonist; IC50 = 6.87 µM; potential in Parkinson’s disease research.Fórmula:C21H25F2NO2Cor e Forma:SolidPeso molecular:361.43GSD-11
GSD-11: Potent, selective anti-austerity agent; blocks Akt/mTOR pathway, hinders PANC-1 cell migration & colony growth. Promising for pancreatic cancer study.Fórmula:C20H28O2Cor e Forma:SolidPeso molecular:300.44(RS)-AMPA hydrobromide
CAS:AMPAR agonistFórmula:C7H11BrN2O4Pureza:98%Cor e Forma:SolidPeso molecular:267.08AY-22,252
CAS:AY-22,252 is an inhibitor of beef heart & rat brain nucleoside-3',5'- monophosphate phosphodiesterase.Fórmula:C27H37NaO7Cor e Forma:SolidPeso molecular:496.57CDK7/12-IN-1
CAS:CDK7/12-IN-1 is a selective CDK7 (IC50: 3 nM) and CDK12 (IC50: 277 nM) inhibitor, effective against tumor growth.Fórmula:C25H34N8OCor e Forma:SolidPeso molecular:462.59Apoptosis inducer 5
Apoptosis Inducer 5, a lignan enantiomer extracted from Crataegus pinnatifida, demonstrates cytotoxic properties through inducing apoptosis and autophagy inFórmula:C23H26O7Cor e Forma:SolidPeso molecular:414.45VU0463271 quarterhydrate
VU0463271 quarterhydrate is a potent KCC2 antagonist, with an IC 50 of 61 nM [1].Fórmula:C19H20N4O2S2Cor e Forma:SolidPeso molecular:38720-HEDE
CAS:20-HEDE (WIT 002) is a 20-hydroxyeicosatetraenoic acid (20-HETE) antagonist.Fórmula:C20H36O3Pureza:98%Cor e Forma:SolidPeso molecular:324.50KRAS inhibitor-8
CAS:KRAS inhibitor-8 is a potent KRAS G12C inhibitor.Fórmula:C26H24ClF4N5O3Pureza:98%Cor e Forma:SolidPeso molecular:565.95YKL-1-116
CAS:YKL-1-116 is an effective, selective, and covalent CDK7 inhibitor.Fórmula:C34H38N8O3Pureza:98%Cor e Forma:SolidPeso molecular:606.72HDAC1-IN-5
HDAC1-IN-5 inhibits HDAC1 (IC50=15 nM) & HDAC6 (IC50=20 nM), promotes apoptosis, damages chromatin, and reduces tumor growth in mice.Fórmula:C20H21N3O2SCor e Forma:SolidPeso molecular:367.46Tenellin
CAS:Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.Fórmula:C21H23NO5Cor e Forma:SolidPeso molecular:369.41DNDI-8219
CAS:DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.Fórmula:C13H10F3N3O5Cor e Forma:SolidPeso molecular:345.23HBV-IN-19 TFA
CAS:HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.Fórmula:C26H31F3N2O8Cor e Forma:SolidPeso molecular:556.53PROTAC CDK12/13 Degrader-1
PROTAC CDK12/13 Degrader-1 (7f) selectively degrades CDK12/13 at nanomolar potency, targeting breast cancer.Cor e Forma:SolidSCH-1473759
CAS:SCH-1473759 is an inhibitor of the aurora (IC50s: 4 and 13 nM for Aurora A and B, respectively).Fórmula:C20H26N8OSPureza:98%Cor e Forma:SolidPeso molecular:426.54PTP1B-IN-19
PTP1B-IN-19, a benzimidazole, selectively inhibits protein tyrosine phosphatase 1B with a Ki of 23.3 μM, potential for type 2 diabetes research.Fórmula:C26H19N3O4SCor e Forma:SolidPeso molecular:469.51PTP1B-IN-3 diammonium
PTP1B-IN-3 diammonium, an oral enzyme inhibitor, has potent antidiabetic and anticancer effects, with a 120 nM IC50.Fórmula:C12H13BrF2N3O3PCor e Forma:SolidPeso molecular:396.12HBV-IN-20
HBV-IN-20 is a potent, orally active HBV inhibitor (EC50: 0.46 μM). HBV-IN-20 is a classical type II CpAM (core protein assembly regulator).Cor e Forma:SolidLatrunculins A
CAS:Latrunculins A is a novel marine toxin, disrupts microfilament organization in cultured cells.Fórmula:C22H31NO6SCor e Forma:SolidPeso molecular:437.55PD 113271
CAS:PD 113,271 is an analog of the fermentation products fostriecin with antitumor activity in vitro and in vivo.Fórmula:C19H27O10PPureza:98%Cor e Forma:SolidPeso molecular:446.39DH376
CAS:DH376 inhibits DAGLα in a time and dose dependent manner in mouse brain. DH376 shows picomolar activity.Fórmula:C31H28F2N4O3Cor e Forma:SolidPeso molecular:542.58MEIS-IN-3
MEIS-IN-3 is a potent inhibitor of MEIS.Fórmula:C25H26N2O4Cor e Forma:SolidPeso molecular:418.48CHNQD-01255
CAS:<p>CHNQD-01255 is an orally active inhibitor of Arf-GEFs that is effective against hepatocellular carcinoma (HCC).</p>Fórmula:C23H29NO6Cor e Forma:SolidPeso molecular:415.48Clavicoronic acid
CAS:Clavicoronic acid, a β-lactamase inhibitor, boosts penicillin antibiotics against resistant bacteria.Fórmula:C15H18O4Cor e Forma:SolidPeso molecular:262.3PRMT5-IN-18
CAS:PRMT5-IN-18 (Compound 002) is a potent inhibitor of PRMT5 and can be used in the study of PRMT5-mediated diseases, such as tumours.Fórmula:C32H42N4O4Cor e Forma:SolidPeso molecular:546.70Tofacitinib Prodrug-1
Tofacitinib Prodrug-1: an oral prodrug reducing Tofacitinib's side effects, treats ulcerative colitis in mice effectively with low toxicity.Fórmula:C36H39ClN10O7Cor e Forma:SolidPeso molecular:759.21Ro-51
CAS:dual P2X3 and P2X2/3 antagonistFórmula:C17H23IN4O4Pureza:98%Cor e Forma:SolidPeso molecular:474.29ETX0282
CAS:ETX0282, oral class A/C β-lactamase inhibitor, developed by Entasis with cefpodoxime for bacterial infections.Fórmula:C13H18FN3O5Cor e Forma:SolidPeso molecular:315.30PARP-1/HDAC-IN-1
CAS:PARP-1/HDAC-IN-1 is a PARP-1 and HDAC6 inhibitor with anticancer, antimigratory, and antiangiogenic activities and is used in tumor research.Fórmula:C22H18N4O4Pureza:95.94%Cor e Forma:SolidPeso molecular:402.4Spliceostatin A
CAS:Spliceostatin A is an anticancer agent and splicing inhibitor that induces apoptosis by inducing cell cycle arrest in the G1 and G2/M phases.Fórmula:C28H43NO8Pureza:94.66%Cor e Forma:SolidPeso molecular:521.643DMGF
CAS:DMGF, a biflavonoid from Taxus, induces apoptosis, autophagy, and inhibits B16F10 cell motility and MMP-2 expression, hindering melanoma metastasis.Fórmula:C32H22O10Cor e Forma:SolidPeso molecular:566.51Acetoxycycloheximide
CAS:<p>Acetoxycycloheximide triggers TNF receptor 1, prompts apoptosis, and cytochrome c release by activating c-Jun N-terminal kinase.</p>Fórmula:C17H25NO6Cor e Forma:SolidPeso molecular:339.38CB30865
CAS:CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.Fórmula:C26H22BrN5O2Pureza:99.04%Cor e Forma:SolidPeso molecular:516.39Rodatristat ethyl
CAS:Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.Fórmula:C29H31ClF3N5O3Pureza:98%Cor e Forma:SolidPeso molecular:590.04TD-0212 TFA
CAS:TD-0212 TFA is an oral AT1 receptor antagonist & NEP inhibitor with pKi 8.9 & pIC50 9.2.Fórmula:C30H35F4N3O6SPureza:98%Cor e Forma:SolidPeso molecular:641.67Dyrk1A-IN-4
CAS:Dyrk1A-IN-4, compound 48, is an oral DYRK1A/DYRK2 inhibitor with IC50s: 2 nM (DYRK1A), 6 nM (DYRK2), anticancer properties.Fórmula:C14H13F3N6Cor e Forma:SolidPeso molecular:322.29Deltasonamide 2 hydrochloride
Deltasonamide 2 hydrochloride is a competitive high-affinity PDEδ inhibitor with a Kd of approximately 385 pM.Fórmula:C30H40Cl2N6O4S2Pureza:98%Cor e Forma:SolidPeso molecular:683.71Anti-MRSA agent 6
Anti-MRSA agent 6 (compound 3q6) is a potent anti-methicillin-resistant Staphylococcus aureus (anti-MRSA) agent with low cytoxicity for MCF-7, A549 cells [1].Fórmula:C16H11F2N3Cor e Forma:SolidPeso molecular:283.28MK-8825
CAS:MK-8825 is a CGRP receptor antagonist.Fórmula:C31H30F2N6O3Cor e Forma:SolidPeso molecular:572.61Mal-PEG4-VA-PBD
CAS:Mal-PEG4-VA-PBD is a drug-linker conjugate for Antibody-Drug Conjugates (ADCs), comprising the antitumor antibiotic Pyrrolobenzodiazepine (PBD), connectedFórmula:C68H79N9O17Pureza:98%Cor e Forma:SolidPeso molecular:1294.41ZINC000104379474
ZINC000104379474 is a compound that targets SARS-CoV-2 endoribonuclease.Fórmula:C27H33N3O10Cor e Forma:SolidPeso molecular:559.57Chitin synthase inhibitor 11
Potent CHS inhibitor with an IC50 of 0.10 mM; exhibits broad-spectrum antifungal properties.Fórmula:C24H24N4O8Cor e Forma:SolidPeso molecular:496.47Ganciclovir monophosphonate
CAS:Ganciclovir monophosphate treats CMV, inhibiting replication in human/animal strains (IC50: 0.01μM).Fórmula:C10H16N5O6PCor e Forma:SolidPeso molecular:333.24p38-α MAPK-IN-5
CAS:p38-α MAPK-IN-5: potent p38α inhibitor, IC50s: 0.1 nM (α), 0.2 nM (β), 944 nM (γ), 4100 nM (δ); anti-inflammatory, promising for asthma/COPD research.Fórmula:C37H49N11O2Cor e Forma:SolidPeso molecular:679.86GLS1 Inhibitor-5
GLS1 Inhibitor-5 (24y): Selective, oral glutaminase 1 inhibitor; IC50 68 nM; induces apoptosis; anti-tumor.Cor e Forma:SolidAntifungal agent 38
Antifungal agent 38, a heterocyclic disulfide, shrinks hyphae and damages cell membranes, causing leakage.Fórmula:C8H12N2S2Cor e Forma:SolidPeso molecular:200.32MSA-2 dimer
CAS:MSA-2 dimer: selective oral non-nucleotide STING agonist, Kd=145 μM, long-term antitumor effect, non-covalent, higher permeability.Fórmula:C29H28O8S2Cor e Forma:SolidPeso molecular:568.66ZL-Pin13
CAS:ZL-Pin13: potent Pin1 inhibitor (IC50: 67 nM), halts MDA-MB-231 cell growth, reduces Pin1 substrates.Fórmula:C24H23ClN2O3SCor e Forma:SoildPeso molecular:454.97GABAA receptor agonist 1
Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.Fórmula:C20H30O3Cor e Forma:SolidPeso molecular:318.45Org-6906
CAS:DCB-3503, a tylophorine analog, may treat cancer and suppress immunity by blocking protein synthesis and modulating HSC70's ATPase activity.Fórmula:C13H16ClNPureza:98%Cor e Forma:SolidPeso molecular:221.73MrgprX2 antagonist-7
MrgprX2 antagonist-7 is an anti-allergic agent with significant anti-allergic effects and inhibits mast cell degranulation.Fórmula:C24H22ClF3N6O3Cor e Forma:SolidPeso molecular:534.92Nonsteroidal aromatase inhibitor 1
Compound 13h, a nonsteroidal aromatase inhibitor, has a potent IC50 of 0.09 nM against CYP19A1, showing promise for breast cancer research.Fórmula:C22H16N4O2Cor e Forma:SolidPeso molecular:368.39Sagopilone
CAS:Sagopilone: synthetic epothilone, inhibits cell division and induces apoptosis, effective in MDR tumors, not P-gp substrate.Fórmula:C30H41NO6SCor e Forma:SolidPeso molecular:543.71SCP1-IN-1
CAS:SCP1-IN-1 (SH T-62) is a potent inhibitor of SCP1, promoting REST degradation and potentially aiding glioblastoma research.Fórmula:C20H19F3N2O7S2Pureza:99.53%Cor e Forma:SoildPeso molecular:520.5Ref: TM-T60077
1mg49,00€5mg104,00€10mg169,00€25mg311,00€50mg472,00€100mg707,00€1mL*10mM (DMSO)119,00€KUSC-5037
KUSC-5037 inhibits HIF-1 (IC50 = 1.2 μM) and mitochondrial complex V/FoF1ATP synthase.Fórmula:C18H17F3N6O2Cor e Forma:SolidPeso molecular:406.13651Anticancer agent 16
Anticancer agent 16 showed good cytotoxic effects on HCT-116 cell line (IC50: 8.55 μM), NCI-H460 cell line (IC50: 5.41 μM) and SKOV3 cell line (IC50: 6.4 μM).Fórmula:C27H33N5O6Cor e Forma:SolidPeso molecular:523.58MSK-195
CAS:MSK-195 is an effective TRPV1 agonist.Fórmula:C28H40N2O5Pureza:98%Cor e Forma:SolidPeso molecular:484.63Fostriecin (free base)
CAS:Fostriecin inhibits PP2A/PP4 (IC50s = 3.2/3 nM), weakly affects topoisomerase II/PP1 (IC50s = 40/131 μM), doesn't inhibit PP2B, and may modify epigenetics.Fórmula:C19H27O9PCor e Forma:SolidPeso molecular:430.39LY309887
CAS:LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.Fórmula:C19H23N5O6SCor e Forma:SolidPeso molecular:449.48DX-9065A HCl hydrate
CAS:DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.Fórmula:C26H39ClN4O8Pureza:98%Cor e Forma:SolidPeso molecular:571.06Equisetin
CAS:Equisetin: a QSI from Fusarium equiseti, curbs P. aeruginosa virulence, fights Gram-positive bacteria & HIV-1 integrase; not antibacterial to Gram-negative.Fórmula:C22H31NO4Pureza:98%Cor e Forma:SolidPeso molecular:373.49BDZ-h
CAS:BDZ-h inhibits both closed/open states of all 4 homomeric & 2 GluA2R-complex AMPA receptors.Fórmula:C21H21N5O3SCor e Forma:SolidPeso molecular:423.49FGFR1 inhibitor-6
FGFR1 inhibitor-6, IC50: 16.31 nM, blocks cell cycle at pro-G1/G2/M and induces apoptosis.Fórmula:C27H19N5O4S2Cor e Forma:SolidPeso molecular:541.6Anti-inflammatory agent 6
Anti-inflammatory agent 6 blocks IKKα/β, IκBα, and NF-κB p65 phosphorylation, key to controlling inflammation.Fórmula:C22H20O12Cor e Forma:SolidPeso molecular:476.39Vanin-1-IN-3
Vanin-1-IN-3 (OMP-7) is a vanin-1 inhibitor with an IC 50 of 0.038 μM [1].Fórmula:C17H22F3NO5Cor e Forma:SolidPeso molecular:377.36SLC4011540
SLC4011540 is a potent and selective SphK1/2 dual inhibitor with Ki value of 120 nM and 90 nM respectively.Fórmula:C24H23ClF3N7OSCor e Forma:SolidPeso molecular:550Atorvastatin 3-Deoxyhept-2E-Enoic Acid
CAS:Atorvastatin 3-Deoxyhept-2E-Enoic Acid, an impurity in Atorvastatin, lowers blood lipids as an HMG-CoA reductase inhibitor.Fórmula:C33H33FN2O4Pureza:98%Cor e Forma:SolidPeso molecular:540.62Dicetrorelix pamoate
CAS:Cetrorelix pamoate is a synthetic decapeptide that acts as a GnRH antagonist, inhibiting the release of LH and FSH from the pituitary.Fórmula:C163H200Cl2N34O34Cor e Forma:SolidPeso molecular:3250.49PPARγ agonist 1
PPARγ agonist 1 is a potent agonist of PPARγ that efficiently activates hPPARγ without causing full agonism, thereby avoiding adverse effects.Fórmula:C34H39NO3Cor e Forma:SolidPeso molecular:509.68Tonantzitlolone
CAS:Tonantzitlolone activates TRPC1/4/5 channels, PKCα/θ, inhibits IRS1/PI3K/AKT, and triggers HSF1 to induce glucose dependence.Fórmula:C26H40O7Cor e Forma:SolidPeso molecular:464.59HIV-1 inhibitor-13
HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).Fórmula:C30H32N6O3Cor e Forma:SolidPeso molecular:524.61HIF-1/2α-IN-1
HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α.Fórmula:C17H16N6O4Cor e Forma:SolidPeso molecular:368.35Pexacerfont
CAS:Pexacerfont (BMS-562086) is a selective antagonist of the corticotropin-releasing factor receptor (IC50: 6.1±0.6 nM for the human CRF1 receptor).Fórmula:C18H24N6OPureza:99.77%Cor e Forma:SolidPeso molecular:340.42SK&F 108361
CAS:SK&F 108361 is a symmetric diol that binds HIV-1 protease symmetrically.Fórmula:C24H48N6O6Cor e Forma:SolidPeso molecular:516.67SDM25N hydrochloride
CAS:δ receptor antagonistFórmula:C26H27ClN2O3Pureza:98%Cor e Forma:SolidPeso molecular:450.96Sesamodil
CAS:Sesamodil (SD 3211) is a novel calcium antagonist that can be used to study hypertension.Fórmula:C29H32N2O6SPureza:98.87% - 99.87%Cor e Forma:SolidPeso molecular:536.64β-N-Acetyl-D-hexosaminidase-IN-1
β-N-Acetyl-D-hexosaminidase-IN-1 is a newly discovered chemical compound that acts as an inhibitor for β-N-acetyl-D-hexosaminidase.Fórmula:C18H13F2NO2SCor e Forma:SolidPeso molecular:345.36CGP 22979
CAS:CGP 22979 is a renal selective vasodilator prodrug.Fórmula:C16H24N4O4Cor e Forma:SolidPeso molecular:336.39Antibacterial agent 69
Antibacterial agent 69 is a novel structural antimicrobial modulator that can be used against lethal multidrug-resistant bacterial infections (MIC: 2.978 μM).Fórmula:C24H19N3O4SCor e Forma:SolidPeso molecular:445.49HIV-1 inhibitor-52
CAS:HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.Fórmula:C46H72FNO5SCor e Forma:SolidPeso molecular:770.13Rubropunctatin
CAS:Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.Fórmula:C21H23NO4Cor e Forma:SolidPeso molecular:353.41FR 900452
CAS:FR 900452 is a platelet activating factor antagonist from fermentatiion products of Streptomyces phaeofaciens.Fórmula:C22H25N3O3SCor e Forma:SolidPeso molecular:411.52MS8511
CAS:MS8511: Selective, irreversible G9a/GLP inhibitor. IC50: 100 nM (G9a), 140 nM (GLP). Lowers H3K9me2, anti-proliferative. Useful in cancer/AD/PWS research.Fórmula:C28H41N5O3Cor e Forma:SolidPeso molecular:495.66(RS)-AMPA
CAS:(RS)-AMPA ((±)-AMPA) is a glutamate analog. (RS)-AMPA is an agonist of effective and selective excitatory neurotransmitter L-glutamic acid.Fórmula:C7H10N2O4Pureza:98%Cor e Forma:SolidPeso molecular:186.17Squalamine lactate
CAS:Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.Fórmula:C37H71N3O8SPureza:98%Cor e Forma:SolidPeso molecular:718.04Afeletecan HCl
CAS:Afeletecan (BAY 56-3722) is a water-soluble, anti-cancer camptothecin conjugated to a carbohydrate, inhibiting DNA replication and inducing apoptosis.Fórmula:C45H50ClN7O11SCor e Forma:SolidPeso molecular:932.44Cdc7-IN-8
CAS:Cdc7-IN-8, inhibits Cdc7 kinase, key in DNA replication, and is promising for cancer research. (WO2021032170A1)Fórmula:C19H21N5O2Cor e Forma:SolidPeso molecular:351.40D18
CAS:D18: Dual agonist for TLR7/8, boosts PD-L1, aids tumor sensitivity to PD-1/PD-L1 inhibitors, and is a cytotoxin for ADC HE-S2.Fórmula:C21H28N6Cor e Forma:SolidPeso molecular:364.49Antitumor agent-42
Antitumor agent-42 inhibits microtubule multimerisation and NO release, exhibiting anti-angiogenic, colony-forming and apoptosis-inducing effects.Fórmula:C24H19BrN2O8SCor e Forma:SolidPeso molecular:575.39(S)-5-hydroxy-6-methoxy Duloxetine maleate
(S)-5-hydroxy-6-methoxy Duloxetine, an active metabolite of the (S)-duloxetine, functions as a serotonin (5-HT) and norepinephrine reuptake inhibitor.Fórmula:C19H21NO3S·C4H4O4Cor e Forma:SolidPeso molecular:459.51ABL-L
CAS:ABL-L is able to induce apoptosis in human laryngeal cancer cells using a p53-dependent pathway.Fórmula:C29H46O6Cor e Forma:SolidPeso molecular:490.67GAT564
GAT564, an allosteric CB1R modulator, shows EC50s of 87 nM (cAMP) & 320 nM (β-arrestin2) and lowers IOP effectively in glaucoma mice.Fórmula:C20H16N2O2SCor e Forma:SolidPeso molecular:348.42CB1/2 agonist 1
Potent CB1/2 agonist 1; crosses blood-brain barrier; anti-inflammatory, analgesic; for multiple sclerosis research.Fórmula:C21H24BrFN2O2Cor e Forma:SolidPeso molecular:435.33Burapitant
CAS:<p>Burapitant (SSR 240600) is a novel non-peptide tachykinin neurokinin 1 (NK) receptor antagonist with anti-coke oven and antidepressant activity.</p>Fórmula:C31H35Cl2F6N3O3Pureza:>99.99% - >99.99%Cor e Forma:SolidPeso molecular:682.52Unoprostone
CAS:Unoprostone is a prostaglandin F2α analogs (PGAs), and reduces intraocular pressure and is used topically for glaucoma or ocular hypertension.Fórmula:C22H38O5Pureza:98%Cor e Forma:SolidPeso molecular:382.53Xeruborbactam
CAS:QPX7728 is an of ultra-broad-spectrum boronic acid beta-lactamase.Fórmula:C10H8BFO4Pureza:98%Cor e Forma:SolidPeso molecular:221.9817β-HSD1-IN-1
17β-HSD1-IN-1 (Compound 1) can be used in the non-small cell lung cancer (NSCLC) research.Fórmula:C21H21NO3Cor e Forma:SolidPeso molecular:335.4L-690330 hydrate
L-690330 hydrate inhibits IMPase; Ki: 0.30 μM (human), 0.42 μM (bovine cortex); 0.27 μM (recom. human), 0.19 μM (bovine).Fórmula:C8H14O9P2Cor e Forma:SolidPeso molecular:316.14c(phg-isoDGR-(NMe)k)
CAS:c (phg-isoDGR- (NMe) k) is a selective and effective α5β1-integrin ligand with IC50 of 2.9 nM.Fórmula:C27H41N9O7Pureza:98%Cor e Forma:SolidPeso molecular:603.67EGFR/HER2-IN-7
EGFR/HER2-IN-7: Potent, selective dual inhibitor for MCF-7 cancer; IC50: EGFR 0.18μM, HER2 0.146μM, DHFR 0.907μM.Fórmula:C19H21N3O2SCor e Forma:SolidPeso molecular:355.45A 74273
CAS:A 74273, a nonpeptidic and renin inhibitor, may be used to treat cardiovascular diseases due to renin inhibition.Fórmula:C44H74N4O8Pureza:98%Cor e Forma:SolidPeso molecular:787.08KRAS G12C inhibitor 37
CAS:KRAS G12C inhibitor 37 targets a key signaling protein, showing promise for cancer research involving KRAS G12C.Fórmula:C35H39F3N8O2Cor e Forma:SolidPeso molecular:660.73rel-MDM2/4-p53-IN-3
rel-MDM2/4-p53-IN-3 inhibits MDM2/4-p53 PPI, IC50: MDM2 18.5nM, MDM4 14.8nM, targets cancer research.Fórmula:C25H24Cl2FN3O3Cor e Forma:SolidPeso molecular:504.38Sulprostone
CAS:EP3 and EP1 receptor agonistFórmula:C23H31NO7SPureza:98%Cor e Forma:White To Off-White SolidPeso molecular:465.56BMS-748730
CAS:BMS-748730, also known as 4′-Hydroxy Dasatinib, is a Dasatinib metabolite.Fórmula:C22H26ClN7O3SCor e Forma:SolidPeso molecular:504.01Agarospirol
CAS:Agarospirol has partial anti-inflammatory activity.Fórmula:C15H26OPureza:98%Cor e Forma:SolidPeso molecular:222.37HDAC6-IN-12
HDAC6-IN-12 is a potent inhibitor of HDAC6 that binds in the DNA chain, causing DNA damage and exhibiting anticancer effects that can be used in cancer researchFórmula:C24H39F2N3O5Cor e Forma:SolidPeso molecular:487.58Diarylalkane derivative 1
CAS:Diarylalkane derivative 1 is used for the research of pancreatitis.Fórmula:C34H51NO4Pureza:98%Cor e Forma:SolidPeso molecular:537.77FXIa-6f
CAS:FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical speciesFórmula:C31H29ClF2N4O4Cor e Forma:SolidPeso molecular:595.04RMS-07
CAS:RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.Fórmula:C35H40N8O2Cor e Forma:SolidPeso molecular:604.74HIV-1 protease-IN-6
HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.Fórmula:C27H31FN2O6SCor e Forma:SolidPeso molecular:530.61KIRA9
KIRA9 inhibits IRE1 with a 4.8 μM IC50, blocking ER-stress-induced mRNA decay and apoptosis by fully binding IRE1's ATP site.Fórmula:C27H27F3N6O3SCor e Forma:SolidPeso molecular:572.6Methyl 5-thia-6,8,11,14-eicosatetraenoate
CAS:Methyl 5-thia-6,8,11,14-eicosatetraenoate is a bioactive chemical.Fórmula:C20H32O2SCor e Forma:SolidPeso molecular:336.53LasR-IN-3
LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.Fórmula:C22H19N3O2Cor e Forma:SolidPeso molecular:357.41Tandutinib (MLN518) HCl
Tandutinib antagonizes FLT3, PDGFR, and c-Kit with an IC50 of ~200 nM.Fórmula:C31H43ClN6O4Pureza:98%Cor e Forma:SolidPeso molecular:599.16TIY-7
TIY-7 is a selective, orally active inhibitor of the promyosin receptor kinase (TRK) enzyme. TIY-7 exhibited anti-tumour effects in a mouse xenograft model.Cor e Forma:SolidCilobamine mesylate
CAS:Cilobamine mesylate is a drug which acts as a norepinephrine-dopamine reuptake inhibitor (NDRI) and has stimulant and antidepressant effects.Fórmula:C18H27Cl2NO4SCor e Forma:SolidPeso molecular:424.38Tetrahydrouridine dihydrate
THU dihydrate, a potent CDA inhibitor, outperforms cytidine by blocking the enzyme's active site.Fórmula:C9H20N2O8Cor e Forma:SolidPeso molecular:284.26LasR-IN-2
LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.Fórmula:C21H16ClN3O2Cor e Forma:SolidPeso molecular:377.82IRL 2500
CAS:IRL 2500 is an antagonist of Endothelin receptor with IC50s of 1.3 and 94 nM for Endothelin A receptor and Endothelin B receptor.Fórmula:C36H35N3O4Pureza:99.36%Cor e Forma:White Crystalline SolidPeso molecular:573.68ATM Inhibitor-4
ATM Inhibitor -4: selective, potent (IC50: 0.32 nM), inhibits PI3K family, stable, stops mTOR at 1 μM.Fórmula:C26H29FN6O3Cor e Forma:SolidPeso molecular:492.55DMP 728
CAS:DMP 728 is an antagonist of Glycoprotein IIb-IIIa.Fórmula:C26H40N8O10SPureza:98%Cor e Forma:SolidPeso molecular:656.71Antiangiogenic agent 2
<p>Antiangiogenic agent 2 (compound 3b) is a potent inhibitor of thymidine phosphorylase (IC50: 39.71 μM) and exhibits anti-angiogenic effects.</p>Fórmula:C26H26FN3O4Cor e Forma:SolidPeso molecular:463.5Antibacterial agent 76
Antibacterial agent 76 (compound 9) is a potent antibacterial agent.Fórmula:C23H27N3O2SCor e Forma:SolidPeso molecular:409.54HPK1-IN-3
HPK1-IN-3: Selective HPK1 inhibitor, ATP-competitive, IC50=0.25nM; boosts IL-2 in PBMCs, EC50=108nM.Fórmula:C23H22F4N6O2Cor e Forma:SolidPeso molecular:490.45Antitrypanosomal agent 6
Compound 18a: potent vs. T. brucei (IC50: 0.47 μM), >2x efficacy compared to Nifurtimox, good ADME, binds AT-rich DNA.Fórmula:C22H29Cl2N5OCor e Forma:SolidPeso molecular:450.4PD-1/PD-L1-IN-13
PD-1/PD-L1-IN-13 is a potent immune checkpoint PD-1/PD-L1 inhibitor with an IC50 value of 10.2 nM for PD-1/PD- L1 interaction.PD-1/PD-L1-IN-13 promotes CD8+ T-Fórmula:C36H34ClF2N3O9Cor e Forma:SolidPeso molecular:726.12UCN-02
CAS:UCN-02 (7-epi-Hydroxystaurosporine) is a PKC inhibitor produced by Streptomyces N-126 strain, which inhibits PKA.Fórmula:C28H26N4O4Pureza:98%Cor e Forma:SolidPeso molecular:482.53JAK-IN-19
JAK-IN-19 inhibits JAK (pIC50: 7.2, 7.7), less so for VEGFR2 (7.0) and Aurora B (5.8).Fórmula:C26H36FN5O2Cor e Forma:SolidPeso molecular:469.59Tovinontrine
CAS:Tovinontrine (IMR-687) (IMR-687) is a potent and selective inhibitor of phosphodiesterase-9 (PDE9), designed to target sickle cell disease treatment.Fórmula:C21H26N6O2Pureza:98.8%Cor e Forma:SolidPeso molecular:394.47Tilpisertib fosmecarbil
CAS:Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.Fórmula:C35H36ClN8O7PCor e Forma:SolidPeso molecular:747.14AFP464 free base
CAS:AFP464 (NSC710464) free base is an active HIF-1α inhibitor (IC50: 0.25 μM) and a potent aryl hydrocarbon receptor (AhR) activator.Fórmula:C22H23F3N4O3Pureza:98%Cor e Forma:SolidPeso molecular:448.44SHR902275
CAS:SHR902275: potent RAF inhibitor, hits RAS mutations, oral use. cRAF IC50=1.6 nM, bRAFwt IC50=10 nM, bRAFV600E IC50=5.7 nM, hinders cell growth.Fórmula:C26H23F3N4O4Cor e Forma:SolidPeso molecular:512.48CDK2-IN-9
CDK2-IN-9: potent CDK2 inhibitor (IC50: 0.63 μM), anti-proliferative, arrests S/G2M cell cycle, induces apoptosis, promising for melanoma study.Fórmula:C21H16ClN3O4SCor e Forma:SolidPeso molecular:441.89L-739750
CAS:L-739,750 is an inhibitor (FTI) of peptidomimetic farnesyltransferase.Fórmula:C23H39N3O6S2Pureza:98%Cor e Forma:SolidPeso molecular:517.7Tyk2-IN-3
CAS:Tyk2-IN-3 is an inhibitor of Tyk2 pseudokinase (IC50: 485 nM).Fórmula:C25H24N6O3S2Pureza:98%Cor e Forma:SolidPeso molecular:520.63KR-67607
CAS:KR-67607, or NTX-101, is a novel 11β-HSD1 inhibitor that protects against eye injury by reducing cortisol and preserving eye structures.Fórmula:C24H29Cl2F3N4O4SCor e Forma:SolidPeso molecular:597.48TLR7/8 antagonist 1
Compound 16c, an imidazoquinoline, is a TLR7/8 agonist; IC50: 3.91 μM (TLR7), 2.19 μM (TLR8); targets TLR-2050 for disease treatment.Fórmula:C24H27N5O2Cor e Forma:SolidPeso molecular:417.5NUCC-555
CAS:NUCC-555 is a first-in-class antagonist of activin. It opens a completely new approach to inhibiting the activity of TGF-beta receptor superfamily members.Fórmula:C25H25N5O3Pureza:98%Cor e Forma:SolidPeso molecular:443.5Valbenazine tosylate
CAS:Valbenazine tosylate, the tosylate salt of valbenazine, is a vesicular monoamine transporter 2 (VMAT2) inhibitor with a Ki value of 150 nM while displaying noFórmula:C38H54N2O10S2Pureza:98%Cor e Forma:SolidPeso molecular:762.97Y1 receptor antagonist 1
CAS:Y1 receptor antagonist 1 is an antagonist of neuropeptide Y1 receptor.Fórmula:C28H33N5O3Pureza:98.17%Cor e Forma:SolidPeso molecular:487.59Plasma kallikrein-IN-2
Plasma kallikrein-IN-2: PKal inhibitor, IC50=0.1 nM. Used in angioedema, diabetic eye disease research.Fórmula:C28H24ClF3N8O3Cor e Forma:SolidPeso molecular:612.99Anticancer agent 53
CAS:Anticancer agent 53 exhibits potent in vitro cytotoxicity, triggers apoptosis, halts S/G2/M cycle, and has antitumor effects without toxicity.Fórmula:C31H25FN4O6SCor e Forma:SolidPeso molecular:600.62USP7-IN-6
CAS:USP7-IN-6 is a potent inhibitor of ubiquitin-specific protease 7 (USP7, IC50: 6.8 nM).Fórmula:C41H43N7O4SPureza:98%Cor e Forma:SolidPeso molecular:729.89AZD-4121
CAS:<p>AZD-4121 is an oral cholesterol absorption inhibitor targeting NPC1L1 for the treatment of dyslipidaemia.</p>Fórmula:C36H39F2N3O7SCor e Forma:SolidPeso molecular:695.77NLRP3-IN-7
NLRP3-IN-7 (Compound 36) is a selective inhibitor of the NLRP3 inflammasome and is able to assemble the NLRP3 inflammasome.Fórmula:C18H15ClN2O4S3Cor e Forma:SolidPeso molecular:454.97Topoisomerase I/II inhibitor 4
Topoisomerase I/II inhibitor 4 halts cell growth and spread, induces apoptosis, and is used in liver cancer research.Fórmula:C27H21N5O6Cor e Forma:SolidPeso molecular:511.49
