Inibidores
Os inibidores são moléculas que se ligam a enzimas, receptores ou outras proteínas para reduzir ou bloquear sua atividade biológica. Esses compostos são amplamente utilizados em pesquisas para estudar vias biológicas, entender mecanismos de doenças e desenvolver medicamentos terapêuticos. Os inibidores desempenham um papel crucial no tratamento de várias doenças, incluindo câncer, doenças cardiovasculares e infecções. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento farmacêutico.
Subcategorias de "Inibidores"
- Angiogénese(2.519 produtos)
- Apoptose(5.787 produtos)
- Ciclo celular/Ponto de verificação(4.446 produtos)
- Cromatina/Epigenética(2.235 produtos)
- Sinalização Citoesquelética(1.381 produtos)
- Dano de DNA/Reparo de DNA(2.824 produtos)
- Endocrinologia/Hormónios(3.500 produtos)
- Enzima(3.639 produtos)
- GPCR/Proteína-G(8.318 produtos)
- Imunologia e Inflamação(3.516 produtos)
- Vírus da Influenza(296 produtos)
- Sinalização JAK/STAT(404 produtos)
- Sinalização MAPK(1.200 produtos)
- Transportador de Membranas/Canal Iónico(2.787 produtos)
- Metabolismo(9.416 produtos)
- Microbiologia/Virologia(6.968 produtos)
- Neurociência(9.920 produtos)
- Outros inibidores(37.928 produtos)
- Oxidação-Redução(41 produtos)
- Sinalização PI3K/Akt/mTOR(1.400 produtos)
- Proteases/Proteassoma(1.596 produtos)
- Células - tronco e Derivados(831 produtos)
- Tirosina Quinase/Adaptador(2.015 produtos)
- Ubiquitinação(1.649 produtos)
Exibir 16 mais subcategorias
Foram encontrados 66627 produtos de "Inibidores"
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Phosal 50 PG
CAS:<p>Phosal 50 PG is a co-solvent used as an emulsifier and stabilizer in the pharmaceutical and cosmetic industries.Phosal 50 PG is used as a dietary supplement.</p>Pureza:98%Cor e Forma:SolidDeoxypseudouridine
CAS:<p>Deoxypseudouridine is a nucleotide analog.</p>Fórmula:C9H12N2O5Cor e Forma:SolidPeso molecular:228.2Ref: TM-T13645
Produto descontinuado(S,S)-Valifenalate
CAS:<p>(S,S)-Valifenalate is an acylamino acid fungicide and is used to control a wide range of fungi belonging to the class of Oomycetes.</p>Fórmula:C19H27ClN2O5Cor e Forma:SolidPeso molecular:398.88Muzolimine
CAS:<p>Muzolimine: a long-acting, high-capacity diuretic for kidney failure/hypertension; withdrawn due to serious neurological side effects.</p>Fórmula:C11H11Cl2N3OCor e Forma:SolidPeso molecular:272.13HT-2 Toxin
CAS:<p>HT-2 Toxin, a deacetylated metabolite of T-2 toxin, impairs protein synthesis and hinders cell proliferation in plants.</p>Fórmula:C22H32O8Pureza:98%Cor e Forma:SolidPeso molecular:424.49Ref: TM-T13726
Produto descontinuadoN-Octylmaleimide
CAS:<p>N-Octylmaleimide is an alkylmaleimide, which can inhibit rat liver glucose 6-phosphatase.</p>Fórmula:C12H19NO2Cor e Forma:SolidPeso molecular:209.283-Hydroxyhippuric acid
CAS:<p>3-Hydroxyhippuric acid is an acyl glycine, which are normally minor metabolites of fatty acids.</p>Fórmula:C9H9NO4Cor e Forma:SolidPeso molecular:195.17GRK2 Inhibitor
CAS:<p>GRK2 Inhibitor is an inhibitor of β-Adrenergic Receptor Kinase 1 (β ARK1).</p>Fórmula:C12H9NO6Cor e Forma:SolidPeso molecular:263.2Cysteinylglycine TFA
CAS:<p>Cysteinylglycine TFA is an endogenous metabolite. It is used in disease diagnosis.</p>Fórmula:C7H11F3N2O5SCor e Forma:SolidPeso molecular:292.23Alminoprofen
CAS:<p>Alminoprofen: NSAID; reduces anaphylactic bronchoconstriction at 30 mg/kg intraduodenally.</p>Fórmula:C13H17NO2Cor e Forma:SolidPeso molecular:219.28Metrizoic acid
CAS:<p>Metrizoic acid is an ionic contrast medium. Metrizoic acid displays high osmolality and has a risk of inducing allergic reactions.</p>Fórmula:C12H11I3N2O4Pureza:98%Cor e Forma:SolidPeso molecular:627.9402PIH
CAS:<p>PIH inhibits ciliogenesis by destabilizing microtubules and blocking Hh signaling, hindering cilia formation and alpha-tubulin disassembly.</p>Fórmula:C20H19N5SPureza:98%Cor e Forma:SolidPeso molecular:361.46L-690330
CAS:<p>L-690330 inhibits human/bovine inositol monophosphatase; Ki: 0.19-0.42 μM. 10x potency vs. mouse/rat IMPase.</p>Fórmula:C8H12O8P2Cor e Forma:SolidPeso molecular:298.12Ref: TM-T15685
Produto descontinuado(S)-Rasagiline
CAS:<p>(S)-Rasagiline is rasagiline S-isomer, and is an agent of anti-Parkinson.</p>Fórmula:C12H13NCor e Forma:SolidPeso molecular:171.24Ref: TM-T13252
Produto descontinuadoSIRT-IN-3
CAS:<p>SIRT-IN-3: potent SIRT1 inhibitor (IC50=17μM), 4x selective over SIRT2, 14x over SIRT3 (IC50s: 74μM & 235μM).</p>Fórmula:C13H12N2OCor e Forma:SolidPeso molecular:212.25Canagliflozin-d4
CAS:<p>Canagliflozin D4 is a deuterium-labeled Canagliflozin. Canagliflozin is an SGLT2 inhibitor.</p>Fórmula:C24H25FO5SPureza:98%Cor e Forma:SolidPeso molecular:448.54Ref: TM-T10669
Produto descontinuadoCeritinib D7
CAS:<p>Ceritinib D7 (LDK378 D7) is a deuterium-labeled Ceritinib. Ceritinib is an ATP-competitive inhibitor of ALK tyrosine kinase.</p>Fórmula:C28H36ClN5O3SPureza:98%Cor e Forma:SolidPeso molecular:565.18Ref: TM-T10766
Produto descontinuado2-Nitrosopyridine
CAS:<p>2-Nitrosopyridine: used in antibiotic synthesis, Click/Diels-Alder reactions, excellent dienophile.</p>Fórmula:C5H4N2OCor e Forma:SolidPeso molecular:108.1sodium 4-pentynoate
CAS:<p>sodium 4-pentynoate is a alkynylacetate analogue.</p>Fórmula:C5H5NaO2Pureza:98%Cor e Forma:SolidPeso molecular:120.085-OxoETE
CAS:<p>5-OxoETE, a dehydrogenase-oxidized 5-HETE, raises neutrophil Ca²⁺ (EC50=2nM) & drives eosinophil migration & MAPK pathway.</p>Fórmula:C20H30O3Pureza:98.59%Cor e Forma:SolidPeso molecular:318.45Golgicide A-1
CAS:<p>Golgicide A-1 (GCA-1) is a moderately potent cis-diastereomer variant of Golgicide A (GCA) specifically designed to inhibit mosquito reproduction.</p>Fórmula:C17H14F2N2Cor e Forma:SolidPeso molecular:284.31Golgicide A-2
CAS:<p>GCA-2 is a potent enantiomer of GCA, selectively and efficiently kills An. stephensi larvae, useful for dengue research.</p>Fórmula:C17H14F2N2Cor e Forma:SolidPeso molecular:284.313,5-Diphenyl pyridine
CAS:<p>Heterocyclic compounds-pyridine,</p>Fórmula:C17H13NCor e Forma:SolidPeso molecular:231.29Valiloxibic acid
CAS:<p>Valiloxibic acid is a prodrug for GHB, a natural psychoactive neurotransmitter and weak GABAB agonist.</p>Fórmula:C9H17NO4Cor e Forma:SolidPeso molecular:203.238(Rac)-Rotigotine hydrochloride
CAS:<p>(Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist of dopamine receptor, a partial the 5-HT1A receptor agonist.</p>Fórmula:C19H26ClNOSCor e Forma:SolidPeso molecular:351.93STING agonist-23
CAS:<p>CF502 (STING agonist-23) is a non-nucleotide that activates STING pathway, boosts immune responses, and shows activity against SARS-CoV.</p>Fórmula:C33H35N13O4Cor e Forma:SolidPeso molecular:677.724',5'-Dibromofluorescein
CAS:<p>4',5'-Dibromofluorescein (Eosinic acid) is a fluorescent dye that can be used as a ligand for protein characterization by spectroscopic analysis.</p>Fórmula:C20H10Br2O5Cor e Forma:Orange Solid PowderPeso molecular:490.10Loviride
CAS:<p>Loviride, a reverse transcriptase inhibitor with IC50 of 0.3 μM, blocks HIV-1/2 and SIV in MT-4 cells.</p>Fórmula:C17H16Cl2N2O2Cor e Forma:SolidPeso molecular:351.23Ref: TM-T15776
Produto descontinuado3-Methylcrotonylglycine
CAS:<p>3-Methylcrotonylglycine is an acyl glycine, a normal amino acid metabolite found in urine.</p>Fórmula:C7H11NO3Pureza:98%Cor e Forma:SolidPeso molecular:157.17Sculponeatin O
CAS:<p>Sculponeatin O may have protective effects on the lipid peroxidation-damaged live cells.</p>Fórmula:C28H40O4Pureza:95.00%Cor e Forma:SolidPeso molecular:440.61Decyl-TPP bromide
CAS:<p>Decyl-TPP bromide ((1-Decyl)triphenylphosphonium bromide) may be used as an intermediate for chemical synthesis and an inactive control or as a reference to</p>Fórmula:C28H36BrPPureza:98%Cor e Forma:SolidPeso molecular:483.46Lupinine
CAS:<p>Lupinine is an alkaloid capable of counteracting ethanol anesthesia. Lupinine is an AChE and BChE inhibitor and potential CD69 activator found in species of Loranthus, Calia, and Lupinus. It may also inhibit heparin.</p>Fórmula:C10H19NOPureza:99.95%Cor e Forma:SolidPeso molecular:169.26Tropinone
CAS:<p>Tropinone used as an intermediate in the synthesis of atropine sulfate, and is a decane alkaloid.</p>Fórmula:C8H13NOPureza:99.90%Cor e Forma:Beige To Brown Crystalline PowderPeso molecular:139.1910Z-Nonadecenoic acid
CAS:<p>10Z-Nonadecenoic acid is a long-chain fatty acid with anti-tumor activity.</p>Fórmula:C19H36O2Pureza:99.43%Cor e Forma:SolidPeso molecular:296.49Compound T69202(SC)
CAS:<p>NBQX (FG9202), an AMPA/kainate receptor blocker, counters glutamate toxicity; water-soluble as disodium salt, has anticonvulsant properties.</p>Fórmula:C12H6N4Na2O6SCor e Forma:SolidPeso molecular:380.2415Ref: TM-T69202
Produto descontinuadoElamipretide
CAS:<p>Elamipretide (SS-31, MTP-131, Bendavia) is a mitochondria-focused peptide that curbs toxic ROS and stabilizes cardiolipin.</p>Fórmula:C32H49N9O5Pureza:98.53% - 99.85%Cor e Forma:SolidPeso molecular:639.79SR17018
CAS:<p>SR17018 is an mu-opioid-receptor (MOR) agonist, binding with GTPγS, with an EC50 of 97 nM.</p>Fórmula:C19H18Cl3N3OPureza:99.89%Cor e Forma:SolidPeso molecular:410.727-Methoxy-1-tetralone
CAS:<p>7-Methoxy-1-tetralone may have insecticidal activity.</p>Fórmula:C11H12O2Pureza:99.93%Cor e Forma:White CrystalPeso molecular:176.21Oxindole
CAS:<p>Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.</p>Fórmula:C8H7NOPureza:99.34%Cor e Forma:Off-White Crystalline PowderPeso molecular:133.15MTP 131 acetate
CAS:<p>MTP 131 (acetate) is a small mitochondrially-targeted tetrapeptide.</p>Fórmula:C34H53N9O7Pureza:99.9%Cor e Forma:SolidPeso molecular:699.84Elamipretide Triacetate
CAS:<p>Elamipretide TriTFA, a tetrapeptide, targets mitochondria, associates with cardiolipin, studied for treating Leber's Optic Neuropathy.</p>Fórmula:C38H61N9O11Pureza:>99.99%Cor e Forma:SolidPeso molecular:819.942-Methyl-5-HT hydrochloride
CAS:<p>2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>Fórmula:C11H15ClN2OPureza:98%Cor e Forma:SolidPeso molecular:226.74-Hydroxybenzyl cyanide
CAS:<p>4-Hydroxybenzyl cyanide (4-Hydroxyphenylacetonitrile) shows strong antioxidative activity.</p>Fórmula:C8H7NOPureza:98.13%Cor e Forma:Light Brown SolidPeso molecular:133.15NLX-204 hydrochloride(2170405-10-2 free base)
<p>NLX-204 hydrochloride is a potent and selective ERK1/2 phosphorylation-preferring serotonin 5 HT1A receptor agonist(pKi = 10.19).</p>Fórmula:C20H23Cl2F2N3O2Pureza:99.59%Cor e Forma:SolidPeso molecular:446.32Pamoic acid
CAS:<p>Pamoic acid is the orphan G protein-coupled receptor GPR35 agonist. Pamoic acid activates ERK and beta-arrestin2 and causes antinociceptive activity.</p>Fórmula:C23H16O6Pureza:99.99%Cor e Forma:Fine Yellow PowderPeso molecular:388.37SR-4370
CAS:<p>SR-4370 is an HDAC inhibitor. SR- 4370 exhibited IC50 values of 0.5 μM, 0.1 μM and 0.06 μM towards HDAC1, HDAC2 and HDAC3, resp.</p>Fórmula:C17H18F2N2OPureza:99.50%Cor e Forma:SolidPeso molecular:304.33p-Toluic Acid
CAS:<p>p-Toluic Acid (4-Methylbenzoic acid) belongs to the class of organic compounds known as benzoic acids. 4-Methylbenzoic acid has been primarily detected in saliva. Within the cell, 4-methylbenzoic acid is primarily located in the cytoplasm.</p>Fórmula:C8H8O2Pureza:99.44%Cor e Forma:Physical Description White Powder Sublimes (Ntp 1992)Peso molecular:136.15Isonicotinic acid
CAS:<p>Isonicotinic acid is a metabolite of Isoniazid.Isonicotinic acid is a useful isomer of nicotinic acid. Isoniazid is converted to Isonicotinic acid by hydrazinolysis, with the biotransformation also to be catalyzed by cytochrome P450 enzymes, such as CYP2C.</p>Fórmula:C6H5NO2Pureza:99.68%Cor e Forma:White To Off-White Crystalline SolidPeso molecular:123.11TFLLR-NH2 2TFA(197794-83-5(free base))
<p>TFLLR-NH2 2TFA(197794-83-5(free base)) is an agonist of PAR1 (EC50 :1.9 μM).</p>Fórmula:C35H55F6N9O10Pureza:99.56%Cor e Forma:SolidPeso molecular:875.87Danoprevir sodium
CAS:<p>Danoprevir sodium is an NS3/4A protease inhibitor used in the treatment of Hepatitis C</p>Fórmula:C35H45FN5NaO9SCor e Forma:SolidPeso molecular:753.82Cebranopadol
CAS:<p>Cebranopadol (GRT6005) is an analgesic NOP and opioid receptor agonist with Kis of 0.9 nM, 0.7 nM, 2.6 nM, 18 nM for human NOP, μ-opioid (MOP), κ-opioid (KOP)</p>Fórmula:C24H27FN2OPureza:98.32% - 99.78%Cor e Forma:SolidPeso molecular:378.484-Hydroxy-6-methylcoumarin
CAS:<p>4-Hydroxy-6-methylcoumarin (4-HMC) is a naturally occurring phenolic compound, a derivative of coumarin, found in a variety of plants, fungi, and bacteria. It has anti-inflammatory and anti-tumor activity.4-HMC is used as a flavoring agent, preservative and antioxidant in the food industry.</p>Fórmula:C10H8O3Pureza:99.95%Cor e Forma:White PowderPeso molecular:176.174-Methoxycoumarine
CAS:<p>4-Methoxycoumarine has antitumour effects.</p>Fórmula:C10H8O3Pureza:99.88%Cor e Forma:SolidPeso molecular:176.17Elamipretide 2TFA
CAS:<p>Elamipretide 2TFA (RX-31 2TFA) is a novel mitochondrion-targeted antioxidant.</p>Fórmula:C36H51F6N9O9Pureza:>99.99%Cor e Forma:SolidPeso molecular:867.84Ref: TM-T8831
Produto descontinuadoRosmanol
CAS:<p>Rosmanol has antioxidant, anti-inflammatory, CNS effects; induces apoptosis in cancer cells; modulates GABAA receptors.</p>Fórmula:C20H26O5Pureza:98.82% - 99.79%Cor e Forma:SolidPeso molecular:346.42CTB
CAS:<p>CTB (Cholera Toxin B subunit) is an activator of p300 histone acetyltransferase and induces apoptosis in MCF-7 cells.</p>Fórmula:C16H13ClF3NO2Pureza:99.82%Cor e Forma:SolidPeso molecular:343.73Coumaran
CAS:<p>Coumaran (2,3-Dihydrobenzofuran) is an acetylcholinesterase (AChE) inhibitor isolated from leaves of L. camara. Coumaran(2,3-Dihydrobenzofuran) can be used as a biopesticide. 2,3-dihydrobenzofuran is a member of the class of 1-benzofurans that is the 2,3-dihydroderivative of benzofuran. It has a role as a metabolite.</p>Fórmula:C8H8OPureza:99.61%Cor e Forma:LiquidPeso molecular:120.15Desidustat
CAS:<p>Desidustat is an inhibitor of HIF hydroxylase.</p>Fórmula:C16H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:332.31Dimethylamine hydrochloride
CAS:<p>Dimethylamine hydrochloride, found in urine, comes from food compound TMAO and NO synthesis inhibitor ADMA, processed by DDAH enzyme.</p>Fórmula:C2H8ClNPureza:98% - 99.89%Cor e Forma:White Solid CrystallinePeso molecular:81.54Ethyl 4-hydroxyphenylacetate
CAS:<p>Ethyl 4-hydroxyphenylacetate is a selective inhibitor of monoamine oxidase A.</p>Fórmula:C10H12O3Pureza:99.89%Cor e Forma:Slightly Yellow LiquidPeso molecular:180.2AM-2232
CAS:<p>AM-2232 (UNII-40KCH8YIKP) is a potent and unselective agonist of the cannabinoid receptors.</p>Fórmula:C24H20N2OPureza:99.37%Cor e Forma:SolidPeso molecular:352.43L-(+)-Abrine
CAS:<p>L-(+)-Abrine (L-N-Methyltryptophan) is a toxic protein found in the jequirity seed.,can be used as a biomarker for abrin exposure.</p>Fórmula:C12H14N2O2Pureza:98.71% - ≥95%Cor e Forma:White PowderPeso molecular:218.25IGFBP-1 Protein, Rat, Recombinant
<p>IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. IGFBP-1 Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26.9 kDa and the accession number is P21743.</p>Peso molecular:26.9 kDa (predicted)COR-001
CAS:<p>Ziltivekimab (COR-001) is a human IL-6 antibody, lowers CRP, and may treat inflammation and heart issues in CKD.</p>Pureza:95%Cor e Forma:Odour LiquidARGX-112
CAS:<p>Temtokibart is a humanized IgG1 λ2 antibody that specifically targets IL22RA1, and is expressed by cells that are deficient in the glutamine synthetase gene.</p>Cor e Forma:Odour LiquidOkadaic acid
CAS:<p>Okadaic acid, a polyether marine toxin, is a highly potent and selective protein phosphatase (PP) inhibitor.</p>Fórmula:C44H68O13Pureza:98%Cor e Forma:White Crystals Or PowderPeso molecular:805anti-TNBC agent-3
CAS:<p>Anti-TNBC agent-3 (compound 3g) is a compound that induces apoptosis and possesses anti-cancer cell proliferation properties.</p>Fórmula:C29H39F2N7OCor e Forma:SolidPeso molecular:539.66Lp-PLA2-IN-15
CAS:<p>Lp-PLA2-IN-15 (example 2) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential application in Alzheimer's disease research [1].</p>Fórmula:C22H17F5N4O3Pureza:98%Cor e Forma:SolidPeso molecular:480.39Ref: TM-T79075
Produto descontinuadoUBP1112
CAS:<p>group III mGlu receptor antagonist</p>Fórmula:C10H14NO5PPureza:98%Cor e Forma:SolidPeso molecular:259.2YM 298198 Hydrochloride
CAS:<p>YM 298198 HCl: non-competitive mGlu1 antagonist, Ki=19 nM. Inactive on mGlu2-7, stronger than CPCCOEt.</p>Fórmula:C18H22N4OSCor e Forma:SolidPeso molecular:342.46Aminobutane bisphosphonate
CAS:<p>Aminobutane bisphosphonate curbs bone loss; may manage hypercalcemia in cancer.</p>Fórmula:C4H13NO6P2Cor e Forma:SolidPeso molecular:233.1Dioxifedrine
CAS:<p>Dioxifedrine is a beta-2 -adrenergic agonist with bronchodilator activity.</p>Fórmula:C10H15NO3Cor e Forma:SolidPeso molecular:197.23Fosfonet sodium
CAS:<p>Fosfonet sodium is a sodium salt of phosphonoacetic acid, effective against herpesviruses by inhibiting viral DNA polymerase.</p>Fórmula:C2H4NaO5PCor e Forma:SolidPeso molecular:162.01PL265
CAS:<p>PL265 is a long-acting dual ENKephalinase inhibitor (DENKi) with analgesic potential.</p>Fórmula:C27H35N2O9PPureza:98%Cor e Forma:SolidPeso molecular:562.55Gacyclidine
CAS:<p>Gacyclidine (OTO311), an NMDA receptor blocker, treats tinnitus and injuries in the brain and spinal cord.</p>Fórmula:C16H25NSPureza:99.85% - 99.92%Cor e Forma:SolidPeso molecular:263.44D(-)-Octopamine CSA salt
CAS:<p>D(-)-Octopamine CSA salt is an agonist of octopamine receptors.</p>Fórmula:C18H27NO6SPureza:98%Cor e Forma:SolidPeso molecular:385.48Mavodelpar free base
CAS:<p>Mavodelpar free acid (REN001 free acid) is an selective agonist of PPARδ.</p>Fórmula:C31H30FNO5Pureza:98%Cor e Forma:SolidPeso molecular:515.57Benzovindiflupyr
CAS:<p>Benzovindiflupyr: a fungicide that inhibits SDH (IC50=5.2nM), halts S. sclerotiorum growth (EC50=0.011μg/ml), and protects crops like eggplants.</p>Fórmula:C18H15Cl2F2N3OCor e Forma:SolidPeso molecular:398.23EGFR-IN-82
CAS:<p>EGFR-IN-82 (Compound 8a) is a potent, orally active inhibitor of EGFR, exhibiting IC50 values of 0.09 nM for EGFR L858R/T790M/C797S and 0.06 nM for EGFR Del19/</p>Fórmula:C32H41BrN9O2PPureza:98%Cor e Forma:SolidPeso molecular:694.6Ref: TM-T78788
Produto descontinuadoGlutaminyl Cyclase Inhibitor 4
CAS:<p>Glutaminyl Cyclase Inhibitor 4 is a potent, selective glutaminyl cyclase (QC) inhibitor (IC50: 6.1 nM). It is a potent anti-Alzheimer’s agent.</p>Fórmula:C22H33N5O3Pureza:98%Cor e Forma:SolidPeso molecular:415.53CXCR4-IN-1
CAS:<p>CXCR4-IN-1 (Example C5), with an IC50 of 20 nM, is a potent inhibitor of CXCR4, applicable for the research of various conditions such as cancer, HIV, diabetic</p>Fórmula:C23H32N6Pureza:98%Cor e Forma:SolidPeso molecular:392.54Ref: TM-T79059
Produto descontinuadoQuestiomycin A derivatives 18 TFA
<p>Questiomycin A derivative 18 TFA exhibits antibacterial, anticancer properties and inhibits GRP78.</p>Fórmula:C16H12F3N3O5Pureza:98.45%Cor e Forma:SoildPeso molecular:383.07Ref: TM-T67717L
Produto descontinuadoSaxitoxinol
CAS:<p>Saxitoxinol is an analog of saxitoxin, a known voltage-gated sodium channel blocker.</p>Fórmula:C10H17N7O3Pureza:98%Cor e Forma:SolidPeso molecular:283.29Ref: TM-T68748
Produto descontinuadoCeronapril
CAS:<p>Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.</p>Fórmula:C21H33N2O6PPureza:97.94%Cor e Forma:SolidPeso molecular:440.47KP372-1
CAS:<p>KP372-1, an Akt inhibitor, blocks PI3K signaling, arrests cell growth, and triggers apoptosis in head/neck squamous cell carcinoma.</p>Fórmula:C20H8N12O2Cor e Forma:SolidPeso molecular:448.36Pazinaclone
CAS:<p>Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.</p>Fórmula:C25H23ClN4O4Pureza:97.79% - 99.07%Cor e Forma:SolidPeso molecular:478.93IDX-375
CAS:<p>IDX-375, a HCV NS5B polymerase inhibitor, is used potentially for the treatment of HCV infection.</p>Fórmula:C29H50N5O7PSPureza:98%Cor e Forma:SolidPeso molecular:643.78Culmerciclib
CAS:<p>Culmerciclib is a cell cycle protein-dependent kinase (CDK) inhibitor that exhibits antitumour effects.</p>Fórmula:C24H27FN8Cor e Forma:SolidPeso molecular:446.52Radafaxine hydrochloride
CAS:<p>Radafaxine hydrochloride is an inhibitor of DAT and NET transporters, and nAChR family modulator.</p>Fórmula:C13H19Cl2NO2Pureza:98%Peso molecular:292.2MEN11467
CAS:<p>MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.</p>Fórmula:C38H40N4O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:600.75DPX-3778
CAS:<p>DPX-3778, a triethanolamine salt, boosts tobacco callus growth 4-5x at 0.124-2.48 μM and slows aging with IAA and kinetin.</p>Fórmula:C16H23ClN4O6Cor e Forma:SolidPeso molecular:402.83DprE1-IN-8
CAS:<p>DprE1-IN-8 is a potent inhibitor of DprE1, exhibiting an IC50 of less than 0.75 μM.</p>Fórmula:C19H12F3N5O4SPureza:98%Cor e Forma:SolidPeso molecular:463.39Ref: TM-T79628
Produto descontinuadoFostedil
CAS:<p>Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.</p>Fórmula:C18H20NO3PSPureza:98%Cor e Forma:SolidPeso molecular:361.4Cebranopadol ((1α,4α)stereoisomer)
CAS:<p>Cebranopadol ((1α,4α)stereoisomer) is a stereoisomer of cebranopadol which is a potent ORL-1 agonist.</p>Fórmula:C24H27FN2OPureza:98%Cor e Forma:SolidPeso molecular:378.48PPARγ-IN-2
CAS:<p>"PPARγ-IN-2 (Compound 5a), a PPARγ inhibitor, exhibits an EC50 of 0.106 μM in inhibiting TG accumulation in 3T3-L1 preadipocytes.</p>Fórmula:C19H21N5OPureza:98%Cor e Forma:SolidPeso molecular:335.4Ref: TM-T79678
Produto descontinuadoBET-IN-15
CAS:<p>BET-IN-15 (compound 1) is a potent, orally active inhibitor of BET, demonstrating inhibitory IC50 values of 0.64 nM for BRD4-BD1 and 0.25 nM for BRD4-BD2.</p>Fórmula:C21H18F2N4O3SPureza:98%Cor e Forma:SolidPeso molecular:444.45Ref: TM-T79167
Produto descontinuadoGR 218,231
CAS:<p>GR 218,231 is a selective antagonist of D3 dopamine receptor.</p>Fórmula:C24H33NO3SPureza:98%Cor e Forma:SolidPeso molecular:415.59CH-100
CAS:<p>CH-100 is a Chinese herbal medicine previously used in the treatment of human hepatitis C.</p>Fórmula:C14H22ClNO3Cor e Forma:SolidPeso molecular:287.78Fotemustine
CAS:<p>Fotemustine: antineoplastic, chloroethylates DNA, blocks synthesis, causes cell arrest/apoptosis, lipophilic, crosses blood-brain barrier.</p>Fórmula:C9H19ClN3O5PCor e Forma:SolidPeso molecular:315.69Erythrityl Tetranitrate
CAS:<p>Erythrityl Tetranitrate, a vasodilator similar to nitroglycerin, was first in "sustained release" tablets; may cause "nitro headache."</p>Fórmula:C4H6N4O12Cor e Forma:SolidPeso molecular:302.11PKUMDL-LTQ-301
CAS:PKUMDL-LTQ-301 is a potent inhibitor of HipA toxin. PKUMDL-LTQ-301 also inhibits E. coli persistence.Fórmula:C30H28N2O4Pureza:98%Cor e Forma:SolidPeso molecular:480.55HPK1-IN-18
CAS:<p>HPK1-IN-18: Potent, specific inhibitor of HPK1, a MAP4K enzyme, for cancer research and treatment.</p>Fórmula:C24H24N4Cor e Forma:LiquidPeso molecular:368.47Neurokinin antagonist 1
CAS:<p>Neurokinin antagonist 1 is a potent is a neuropeptide antagonist that can be used to study neurological disorders.</p>Fórmula:C38H40N4O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:600.75BChE-IN-17
CAS:<p>BChE-IN-17 (compound 6n) is a potent, selective inhibitor of butyrylcholinesterase (BChE), demonstrating inhibitory half-maximal inhibitory concentrations (</p>Fórmula:C23H23BrN2O4S2Cor e Forma:SolidPeso molecular:535.47CGP 44532
CAS:<p>CGP 44532 a GABAB receptor agonist.</p>Fórmula:C4H12NO3PPureza:98%Cor e Forma:SolidPeso molecular:153.12CK176
CAS:<p>CK176 is an HIV-1 inhibitor, 11x more effective than I-XW-053 in human PBMCs.</p>Fórmula:C21H12IN3O2Pureza:98%Cor e Forma:SolidPeso molecular:465.24HBV-IN-34
CAS:<p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>Fórmula:C21H19F2N7Pureza:98%Cor e Forma:SolidPeso molecular:407.42Ref: TM-T79469
Produto descontinuado(E)-Crotylbarbital
CAS:<p>(E)-Crotylbarbital, a Crotylbarbital isomer, is a sedative with hypnotic, anticonvulsant properties, aiding sleep and mental stability.</p>Fórmula:C10H14N2O3Pureza:99.94%Cor e Forma:SolidPeso molecular:210.23FM-24 HCl
CAS:<p>FM-24 HCl is a long acting beta-adrenergic receptor antagonist.</p>Fórmula:C19H30ClNO2Cor e Forma:SolidPeso molecular:339.9Trimetoquinol HCl hydrate
CAS:<p>Trimetoquinol hydrochloride possesses differential and selective beta-adrenergic properties.</p>Fórmula:C19H26ClNO6Cor e Forma:SolidPeso molecular:399.87FGFR1 inhibitor-10
CAS:<p>FGFR1 inhibitor-10 (Compound 4i), with an IC50 of 28 nM, effectively inhibits FGFR1 phosphorylation.</p>Fórmula:C26H30F3N7O2SPureza:98%Cor e Forma:SolidPeso molecular:561.62Ref: TM-T79686
Produto descontinuadoAlbuterol stearate
CAS:<p>Albuterol stearate, a salt form of Albuterol, is a selective beta2 agonist for treating asthma and COPD, with 29x preference for beta2 over beta1.</p>Fórmula:C31H57NO5Pureza:98%Cor e Forma:SolidPeso molecular:523.799Anti-NASH agent 1
CAS:<p>Anti-NASH Agent 1 (Compound 3d), derived from Elafibranor, serves as a strong PPAR-α/δ agonist aimed at treating nonalcoholic steatohepatitis (NASH).</p>Fórmula:C26H33NO4Pureza:98%Cor e Forma:SolidPeso molecular:423.54Ref: TM-T79454
Produto descontinuadoOxitropium Bromide
CAS:<p>Oxitropium bromide, a mAChR blocker, treats asthma and COPD as an anticholinergic bronchodilator.</p>Fórmula:C19H26BrNO4Pureza:98%Cor e Forma:SolidPeso molecular:412.32SR14150
CAS:<p>SR14150 is a partial agonist of high-affinity NOP receptor.</p>Fórmula:C21H30N2OPureza:98%Cor e Forma:SolidPeso molecular:326.48ALPK1-IN-2
CAS:<p>ALPK1-IN-2 is a potent inhibitor of ALPK1 (α-kinase 1) (IC50: 95 nM). ALPK1-IN-2 inhibits NF-κB (IC50: 1.31 μM).</p>Fórmula:C20H18F2N4O2SCor e Forma:SolidPeso molecular:416.44Ref: TM-T62162
Produto descontinuadoLp-PLA2-IN-16
CAS:<p>Lp-PLA2-IN-16 (Example 1) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential applications in Alzheimer's disease research [1].</p>Fórmula:C22H17F5N4O3Pureza:98%Cor e Forma:SolidPeso molecular:480.39Ref: TM-T79076
Produto descontinuadoLp-PLA2-IN-12
CAS:<p>Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease (AD), glaucoma, age-</p>Fórmula:C24H23F2N5O3Pureza:98%Cor e Forma:SolidPeso molecular:467.47Ref: TM-T79010
Produto descontinuadoJAK2-IN-9
CAS:<p>Compound A8, known as JAK2-IN-9, is a selective JAK2 inhibitor with an IC50 of 5 nM.</p>Fórmula:C20H24N6O2SPureza:98%Cor e Forma:SolidPeso molecular:412.51Ref: TM-T79581
Produto descontinuadoPhenazolam
CAS:<p>Phenazolam is an analytical reference standard categorized as a benzodiazepine. [1] This product is intended for research and forensic applications.</p>Fórmula:C17H12BrClN4Cor e Forma:SolidPeso molecular:387.66ALPK1-IN-1
CAS:<p>ALPK1-IN-1 (A001) strongly inhibits ALPK1, key for innate immunity & NF-κB signaling via TIFA/TRAF.</p>Fórmula:C25H32N6O2SCor e Forma:SolidPeso molecular:480.63(S)-Coriolic acid
CAS:<p>(S)-Coriolic acid, a 15-LOX metabolite and signaling molecule, modulates cell growth, tumor adhesion, receptor expression, and can cause mitochondrial damage.</p>Fórmula:C18H32O3Pureza:97.67% - 98.04%Cor e Forma:SolidPeso molecular:296.44anti-TNBC agent-2
CAS:<p>Anti-TNBC agent-2 (3j), a purine derivative, acts as an anti-triple negative breast cancer (TNBC) therapeutic.</p>Fórmula:C28H37ClFN7OPureza:98%Cor e Forma:SolidPeso molecular:542.09Ref: TM-T79699
Produto descontinuadoAKOS-22
CAS:<p>AKOS-22: potent VDAC1 inhibitor, Kd=15.4 μM; prevents mitochondrial dysfunction and apoptosis.</p>Fórmula:C22H21ClF3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:467.87Bromadoline maleate
CAS:<p>Bromadoline is an opioid analgesic selective for the μ-opioid receptor.</p>Fórmula:C19H25BrN2O5Pureza:98%Cor e Forma:SolidPeso molecular:441.322AMPK activator C2
CAS:<p>AMPK activator C2 is an AMPK allosteric activator.</p>Fórmula:C7H6NO6PPureza:98%Cor e Forma:SolidPeso molecular:231.1PSB-6426
CAS:<p>PSB-6426 is the first potent and selective human nucleoside triphosphate diphosphohydrolase-2 inhibitor.</p>Fórmula:C22H29N4O10PPureza:98%Cor e Forma:SolidPeso molecular:540.46PAD4-IN-2
CAS:<p>PAD4-IN-2 (compound 5i) is a PAD4 inhibitor with an IC50 value of 1.94 μM, shown to suppress tumor growth in mice through specific inhibition of the PAD4-H3cit-</p>Fórmula:C20H23BClN7O6Cor e Forma:SolidPeso molecular:503.7H 35-25
CAS:<p>H 35-25 is a beta 2-antagonist.</p>Fórmula:C13H21NOCor e Forma:SolidPeso molecular:207.31SB251023
CAS:<p>SB251023 is an agonist of β3-adrenoceptor.</p>Fórmula:C28H34NO6PCor e Forma:SolidPeso molecular:511.55PS372424 HCl
CAS:<p>PS372424 activates CXCR3, triggers ERK phosphorylation, and inhibits CXCL11's effect on CD45+ cell migration in humanized mice.</p>Fórmula:C33H45ClN6O4Cor e Forma:SolidPeso molecular:625.21MitoE10
CAS:<p>MitoE10 is an effective mitochondrial targeting antioxidant.</p>Fórmula:C42H55O5PSCor e Forma:SolidPeso molecular:702.92STAT3-IN-18
CAS:<p>STAT3-IN-18 (compound SPP), a platinum (IV) complex featuring an axial ligand from sandalwood, suppresses the JAK2-STAT3 pathway in breast cancer (BC) cells and</p>Fórmula:C18H24Cl2N2O6PtPureza:98%Cor e Forma:SolidPeso molecular:630.38Bumetanide sodium
CAS:<p>Bumetanide sodium, a potent diuretic, blocks NKCC1 (IC50: 0.68 μM) and NKCC2 (IC50: 4.0 μM).</p>Fórmula:C17H19N2NaO5SCor e Forma:SolidPeso molecular:386.4Tibremciclib
CAS:<p>Tibremciclib is a cyclin-dependent kinase 4 (CDK4) inhibitor that exhibits antineoplastic properties [1].</p>Fórmula:C28H32F2N8Pureza:98%Cor e Forma:SolidPeso molecular:518.6I-BET282
CAS:<p>BET-IN-1 is a bromodomain inhibitor extracted from patent WO/2013024104A1 (example 2, plC50: 6.0 - 7.0).</p>Fórmula:C25H30N4O4Pureza:98%Cor e Forma:SolidPeso molecular:450.53Cap-dependent endonuclease-IN-9
CAS:<p>Cap-dependent endonuclease-IN-9, a strong influenza inhibitor, shows low toxicity, good pharmacokinetics, and dynamic action.</p>Fórmula:C29H22F2N4O7SPureza:98%Cor e Forma:SolidPeso molecular:608.57Ref: TM-T72125
Produto descontinuadoAnti-MI/R injury agent 1
CAS:<p>Anti-MI/R injury agent 1 (compound 18), derived from Panaxatriol, represents an orally administered, potent agent against myocardial ischemia/reperfusion (MI/R</p>Fórmula:C32H49NO6Cor e Forma:SolidPeso molecular:543.73PI3Kδ-IN-13
CAS:<p>PI3Kδ-IN-13 (compound 89), with an IC50 value of 2.6 nM, is an inhibitor of PI3Kδ, applicable for researching diseases involving cell proliferation, including</p>Fórmula:C27H39N7O4S2Cor e Forma:SolidPeso molecular:589.77Davelizomib
CAS:<p>Davelizomib is a proteasome inhibitor that exhibits antineoplastic activity [1].</p>Fórmula:C21H26BF2N3O7Pureza:98%Cor e Forma:SolidPeso molecular:481.25HBV-IN-38
CAS:<p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>Fórmula:C18H16F3N5O4S2Pureza:98%Cor e Forma:SolidPeso molecular:487.48Lerzeparib
CAS:<p>Lerzeparib is a PARP (ADP-ribose polymerase) inhibitor that exhibits antineoplastic activity [1].</p>Fórmula:C21H20FN3O2Pureza:98%Cor e Forma:SolidPeso molecular:365.4Insecticidal agent 6
CAS:<p>Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.</p>Fórmula:C19H14BrCl2N5O4Pureza:98%Cor e Forma:SolidPeso molecular:527.16Canlitinib
CAS:<p>Canlitinib, a tyrosine kinase inhibitor, holds potential for cancer research.</p>Fórmula:C33H31F2N3O7Pureza:98%Cor e Forma:SolidPeso molecular:619.61Civorebrutinib
CAS:<p>Civorebrutinib (WS-413) is an inhibitor of Bruton's tyrosine kinase that exhibits antineoplastic activity [1].</p>Fórmula:C23H22ClN7O2Cor e Forma:SolidPeso molecular:463.92Antitumor photosensitizer-1
CAS:<p>Antitumor Photosensitizer-1 (Compound 8) is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity,</p>Fórmula:C42H51N5O6Cor e Forma:SolidPeso molecular:721.88IDO1-IN-22
CAS:<p>IDO1-IN-22 (Compound 3) is an inhibitor of IDO1, demonstrating potent activity with biochemical hIDO1 IC50 of 67.4 nM and HeLa hIDO1 IC50 of 17.6 nM.</p>Fórmula:C12H12BrFN6O3Pureza:98%Cor e Forma:SolidPeso molecular:387.16EST73502
CAS:<p>EST73502 is a compound that functions as a dual agonist for the μ-opioid receptor (MOR) and an antagonist for the σ1 receptor (σ1R). It is selective, orally active, and possesses the ability to penetrate the blood-brain barrier (BBB). The compound exhibits a Ki value of 64 nM for the MOR and 118 nM for the σ1R. Additionally, EST73502 demonstrates antinociceptive activity [1].</p>Fórmula:C19H26F2N2O2Pureza:98%Cor e Forma:SolidPeso molecular:352.426CIAC001
CAS:<p>CIAC001, a pyruvate kinase PKM2 inhibitor, exhibits anti-neuroinflammatory properties.</p>Fórmula:C20H25N3O2Cor e Forma:SolidPeso molecular:339.43Omeprazole acid
CAS:<p>Omeprazole treats GERD, ulcers, Zollinger-Ellison syndrome, prevents GI bleeding; it's a proton pump inhibitor.</p>Fórmula:C34H32N6Na2O10S2Cor e Forma:SolidPeso molecular:794.76JAK1-IN-10
CAS:<p>JAK1-IN-10 (compound 9), a cyano-substituted cyclic hydrazine derivative, functions as a potent and selective inhibitor of JAK1 [1].</p>Fórmula:C15H17N7Pureza:98%Cor e Forma:SolidPeso molecular:295.34JAK-IN-27
CAS:<p>JAK-IN-27, also known as compound 1, is an orally active, potent inhibitor of the JAKS family kinases, displaying inhibitory concentrations (IC50s) of 3.0 nM</p>Fórmula:C20H21F2N7OPureza:98%Cor e Forma:SolidPeso molecular:413.42JDB175
CAS:<p>JDB175, a selective BTK inhibitor with oral bioavailability, demonstrates excellent penetration through the blood-brain barrier.</p>Fórmula:C26H21F3N4O2Pureza:98%Cor e Forma:SolidPeso molecular:478.47Syk-IN-8
CAS:<p>Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.</p>Fórmula:C23H26N10Pureza:98%Cor e Forma:SolidPeso molecular:442.52Azilsartan mepixetil potassium
CAS:<p>Azilsartan medoxomil potassium (QR-01019K), an angiotensin II receptor antagonist, exhibits a potent and sustained antihypertensive effect, along with a more</p>Fórmula:C36H33KN6O8Cor e Forma:SolidPeso molecular:716.78S1P1 agonist 6
CAS:<p>Compound I (S1P1 agonist 6) is an S1P1 agonist that mitigates autoimmune activity by inhibiting lymphocyte trafficking and has potential as an immunosuppressive</p>Fórmula:C25H26F3NO3Pureza:98%Cor e Forma:SolidPeso molecular:445.47Mal-VC-PAB-PNP-CDN-A
CAS:<p>Mal-VC-PAB-PNP-CDN-A is a conjugate comprised of an agent and a linker, utilized in antibody-drug conjugates (ADC) [1] [2].</p>Fórmula:C51H67N17O20P2Cor e Forma:SolidPeso molecular:1300.13TrkB-IN-1
CAS:<p>TrkB-IN-1 is a potent, orally active agonist of the TrkB receptor, with favorable pharmacokinetic (PK) properties.</p>Fórmula:C19H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:368.34BTK-IN-25
CAS:<p>BTK-IN-25 (compound 71) is a potent BTK inhibitor, demonstrating an IC50 of 0.77 nM against BTK(C481S) and achieving an IC50 of 1 nM in DOHH2 cells [1].</p>Fórmula:C28H27F2N3O5Pureza:98%Cor e Forma:SolidPeso molecular:523.53JAK1-IN-11
CAS:<p>JAK1-IN-11 (compound 11) serves as a potent inhibitor of Janus kinases, exhibiting nanomolar inhibitory concentrations with IC50 values of 0.02 nM (JAK1) and 0.</p>Fórmula:C26H36N6O4SPureza:98%Cor e Forma:SolidPeso molecular:528.67PF-05236216 hydrochloride
CAS:<p>PF-05236216 hydrochloride: Brain-penetrant, potent CK1δ/ε inhibitor affecting mouse circadian rhythms.</p>Fórmula:C18H15FN4OCor e Forma:SolidPeso molecular:322.34Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan
CAS:<p>Mal-cyclohexane-Gly-Gly-Phe-Gly-Exatecan is a linker molecule employed in the synthesis of antibody-drug conjugates (ADCs), demonstrating potent antitumor</p>Fórmula:C55H60FN9O13Cor e Forma:SolidPeso molecular:1074.12Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE
CAS:<p>Compound S6, Mc-Alanyl-Alanyl-Asparagine-PAB-MMAE, is a potent anticancer agent specifically activated by the tumor microenvironment; it demonstrates efficacy</p>Fórmula:C67H101N11O16Pureza:98%Cor e Forma:SolidPeso molecular:1316.58Antitumor photosensitizer-2
CAS:<p>Compound 11, also known as Antitumor Photosensitizer-2, is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-</p>Fórmula:C40H47N5O7Cor e Forma:SolidPeso molecular:709.83Antibacterial agent 157
CAS:<p>Compound B12 (Antibacterial agent 157) is a fungicidal agent that can impact protein synthesis in Botrytis cinerea.</p>Fórmula:C26H23BrF4N2O3Cor e Forma:SolidPeso molecular:567.37CGP 56999A
CAS:<p>CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.</p>Fórmula:C19H30NO5PPureza:98%Cor e Forma:SolidPeso molecular:383.42Py-MAA-Val-Cit-PAB-MMAE
CAS:<p>Py-MAA-Val-Cit-PAB-MMAE (AAJ8D6-PY-Val-Cit-MMAE) serves as an ADC linker for Zapadcine-3a, a broad-spectrum anti-TRAILR2 ADC with antineoplastic properties.</p>Fórmula:C72H111N13O16SCor e Forma:SolidPeso molecular:1446.79Bi-Mc-VC-PAB-MMAE
CAS:<p>Bi-Mc-VC-PAB-MMAE is an agent-linker conjugate for antibody-drug conjugates (ADCs), featuring the linker (Fmoc-Val-Cit-PAB) and the potent tubulin inhibitor (</p>Fórmula:C71H104N12O18Cor e Forma:SolidPeso molecular:1413.66LFS-1107
CAS:<p>LFS-1107, a reversible CRM1 inhibitor (Kd: 12.5 pM), selectively targets and eliminates ENKTL cells, offering potential for cancer research applications [1].</p>Fórmula:C12H11N5OS2Pureza:98%Cor e Forma:SolidPeso molecular:305.38APG-2449
CAS:<p>APG-2449 is an orally active inhibitor targeting ALK, ROS1, and FAK, demonstrating antitumor efficacy in mouse models of non-small cell lung cancer (NSCLC) [1].</p>Fórmula:C33H42ClN5O4SPureza:98%Cor e Forma:SolidPeso molecular:640.24Ref: TM-T79363
Produto descontinuadoLM2I
CAS:<p>LM2I, a derivative of Spinosyn A (SPA), serves both as an argininosuccinate synthase (ASS1) enzyme activator and a tumor inhibitor through direct interaction</p>Fórmula:C47H77N3O11Cor e Forma:SolidPeso molecular:860.13YK-029A
CAS:<p>YK-029A, an orally active EGFR mutant inhibitor, targets both EGFR T790M and EGFRex20ins mutations.</p>Fórmula:C27H32N8O2Pureza:98%Cor e Forma:SolidPeso molecular:500.6Ref: TM-T79461
Produto descontinuadoFAP-IN-2
CAS:<p>FAP-IN-2 is a 99mTc-labeled, isonitrile-containing derivative of a fibroblast activation protein (FAPI) inhibitor suitable for tumor imaging [1].</p>Fórmula:C24H28F2N6O3Cor e Forma:SolidPeso molecular:486.51FLT3-IN-19
CAS:<p>FLT3-IN-19 (Comp 50) is a potent, selective inhibitor of FLT3, demonstrating an IC50 value of 0.213 nM, and is applicable in research pertaining to acute</p>Fórmula:C22H26N8OCor e Forma:SolidPeso molecular:418.49MDVN1003
CAS:<p>MDVN1003 inhibits BTK & PI3Kδ in B cells, blocking NHL growth; it kills lymphoma cells, not erythroblasts.</p>Fórmula:C22H20FN7OPureza:98%Cor e Forma:SolidPeso molecular:417.44ATR-IN-24
CAS:<p>ATR-IN-24 (Compound 1) is an ATR inhibitor with demonstrated anticancer activity [1].</p>Fórmula:C23H26N6O2Pureza:98%Cor e Forma:SolidPeso molecular:418.49Ref: TM-T79058
Produto descontinuadoBTK-IN-27
CAS:<p>BTK-IN-27 (example 8), a potent BTK inhibitor with an IC50 of 0.2 nM, demonstrates anti-proliferative effects in TMD8 cells with an IC50 of less than 5 nM.</p>Fórmula:C31H35N7O2Pureza:98%Cor e Forma:SolidPeso molecular:537.66Estrogen receptor modulator 8
CAS:<p>Estrogen Receptor Modulator 8 (compound 4) is an orally active inhibitor targeting Estrogen Receptor/ERR α with potent efficacy (IC50 = 0.437 nM in MCF-7 cells</p>Fórmula:C25H24F4N2O2Pureza:98%Cor e Forma:SolidPeso molecular:460.46(αR)-Cyclopropaneacetamide-Exatecan
CAS:<p>(αR)-Cyclopropaneacetamide-Exatecan (compound 2-A), an Exenotecan derivative, serves as a cytotoxic agent that effectively inhibits the proliferation of U87MG</p>Fórmula:C29H28FN3O6Cor e Forma:SolidPeso molecular:533.55DiaFluo
CAS:<p>DiaFluo is a probe for protein S-sulfinylation from cells.</p>Fórmula:C32H32N4O9SCor e Forma:SolidPeso molecular:648.69Ref: TM-T31416
Produto descontinuadoBelfosdil
CAS:<p>Belfosdil is a blocker of antihypertensive calcium channel.</p>Fórmula:C27H50O7P2Pureza:98%Cor e Forma:SolidPeso molecular:548.63FOXM1-IN-2
CAS:<p>FOXM1-IN-2, a FOXM1 inhibitor, exhibits antineoplastic activity [1].</p>Fórmula:C48H47F4N7O12SCor e Forma:SolidPeso molecular:1021.99Immune cell migration-IN-1
CAS:<p>Immune cell migration-IN-1 (compound 2) serves as a potent inhibitor of immune cell migration, with potential research applications for mitigating conditions</p>Fórmula:C30H25ClN4O6SCor e Forma:SolidPeso molecular:605.06Yhhu6669
CAS:<p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>Fórmula:C29H28ClFN6O3Pureza:98%Cor e Forma:SolidPeso molecular:563.02Ref: TM-T78756
Produto descontinuadoL 689037
CAS:<p>L 689037 is an inhibitor of leukotriene biosynthesis.</p>Fórmula:C36H37ClN2O4Pureza:98%Cor e Forma:SolidPeso molecular:597.14HPK1-IN-38
CAS:<p>HPK1-IN-38 (compound 15) is an inhibitor of MAP4K1/HPK1, suitable for research into disorders related to HPK1 [1].</p>Fórmula:C29H29N5O3Cor e Forma:SolidPeso molecular:495.57BET-IN-14
CAS:<p>BET-IN-14 is a pan BET inhibitor with an IC50 of 5.35 nM, demonstrating oral activity and anticancer properties [1].</p>Fórmula:C30H37N7O2Pureza:98%Cor e Forma:SolidPeso molecular:527.66DPP
CAS:<p>DPP, a Platinum(IV) complex with a pterostilbene-derived axial ligand, inhibits the JAK2-STAT3 pathway in breast cancer (BC) cells, demonstrating</p>Fórmula:C36H40Cl2N2O10PtPureza:98%Cor e Forma:SolidPeso molecular:926.7Xilmenolone
CAS:<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Fórmula:C26H37N3O2Pureza:98%Cor e Forma:SolidPeso molecular:423.59Ref: TM-T78670
Produto descontinuadoTauro-Obeticholic Acid sodium
CAS:<p>Tauro-obeticholic acid, a farnesoid X receptor (FXR) agonist and semisynthetic derivative of chenodeoxycholic acid, is an active metabolite of obeticholic acid.</p>Fórmula:C28H48NO6S·NaCor e Forma:SolidPeso molecular:549.74MOR agonist-1
CAS:<p>MOR Agonist-1 is a μ-opioid receptor (MOR) agonist noted for its potent analgesic properties and is utilized in research concerning pain and associated</p>Fórmula:C22H26ClFN2O2Pureza:98%Cor e Forma:SolidPeso molecular:404.91JAK-IN-34
CAS:<p>JAK-IN-34 (compound 11n) is a potent inhibitor of Janus kinases (JAKs), demonstrating IC50 values of 0.40 nM for JAK1, 0.83 nM for JAK2, 2.10 nM for JAK3,</p>Fórmula:C27H26N6OPureza:98%Cor e Forma:SolidPeso molecular:450.53URAT1 inhibitor 5
CAS:<p>URAT1 Inhibitor 5 (compound 16) serves as a powerful inhibitor of URAT1 and is utilized in hyperuricemia research [1].</p>Fórmula:C18H14BrN3O2SCor e Forma:SolidPeso molecular:416.29ROCK2-IN-6
CAS:<p>ROCK2-IN-6 (Comp A) is a selective inhibitor of ROCK2, applicable in the study and treatment of ROCK-mediated, autoimmune, and inflammatory diseases [1].</p>Fórmula:C26H21F2N7OPureza:98%Cor e Forma:SolidPeso molecular:485.49ALPK1-IN-3
CAS:<p>ALPK1-IN-3,serves as an ALPK1 inhibitor that dampens proinflammatory gene expression in the kidney and enhances survival in animal models of sepsis-induced</p>Fórmula:C20H16F2N4OSPureza:98%Cor e Forma:SolidPeso molecular:398.43DDO-2213
CAS:<p>DDO-2213 is a potent, orally active inhibitor of the WDR5-MLL1 interaction, demonstrating an IC50 of 29 nM and a Kd of 72.9 nM against WDR5.</p>Fórmula:C24H27ClFN7OCor e Forma:SolidPeso molecular:483.97BBDDL2059
CAS:<p>BBDDL2059 is a selective covalent inhibitor targeting EZH2, exhibiting an IC50 of 1.5 nM against the EZH2-Y641F mutant.</p>Fórmula:C27H36N4O4SPureza:98%Cor e Forma:SolidPeso molecular:512.66Ref: TM-T79200
Produto descontinuadoIDO/Tubulin-IN-2
CAS:<p>IDO/Tubulin-IN-2 inhibits TDO/tubulin, effective on U87, HepG2, A549, HCT-116, LO2 cancer cells; IC50 values 0.036-1.04 μM, boosts antitumor action.</p>Fórmula:C48H40N6O10Cor e Forma:SolidPeso molecular:860.87VISTA-IN-2
CAS:<p>VISTA-IN-2 (Compound 1) is a V-domain Ig suppressor of T-cell activation (VISTA) inhibitor that promotes the degradation of VISTA in cells via autophagy,</p>Fórmula:C23H23N3OPureza:98%Cor e Forma:SolidPeso molecular:357.45Ref: TM-T79653
Produto descontinuadoMDL-811
CAS:<p>MDL-811, an allosteric activator of SIRT6, markedly enhances the deacetylation of histone H3 at lysine residues 9, 18, and 56 (H3K9Ac, H3K18Ac, and H3K56Ac),</p>Fórmula:C25H25BrCl2FN3O5S2Pureza:98%Cor e Forma:SolidPeso molecular:681.42
