Inibidores
Os inibidores são moléculas que se ligam a enzimas, receptores ou outras proteínas para reduzir ou bloquear sua atividade biológica. Esses compostos são amplamente utilizados em pesquisas para estudar vias biológicas, entender mecanismos de doenças e desenvolver medicamentos terapêuticos. Os inibidores desempenham um papel crucial no tratamento de várias doenças, incluindo câncer, doenças cardiovasculares e infecções. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento farmacêutico.
Subcategorias de "Inibidores"
- Angiogénese(2.519 produtos)
- Apoptose(5.787 produtos)
- Ciclo celular/Ponto de verificação(4.446 produtos)
- Cromatina/Epigenética(2.235 produtos)
- Sinalização Citoesquelética(1.381 produtos)
- Dano de DNA/Reparo de DNA(2.824 produtos)
- Endocrinologia/Hormónios(3.500 produtos)
- Enzima(3.639 produtos)
- GPCR/Proteína-G(8.318 produtos)
- Imunologia e Inflamação(3.516 produtos)
- Vírus da Influenza(296 produtos)
- Sinalização JAK/STAT(404 produtos)
- Sinalização MAPK(1.200 produtos)
- Transportador de Membranas/Canal Iónico(2.787 produtos)
- Metabolismo(9.416 produtos)
- Microbiologia/Virologia(6.968 produtos)
- Neurociência(9.920 produtos)
- Outros inibidores(37.928 produtos)
- Oxidação-Redução(41 produtos)
- Sinalização PI3K/Akt/mTOR(1.400 produtos)
- Proteases/Proteassoma(1.596 produtos)
- Células - tronco e Derivados(831 produtos)
- Tirosina Quinase/Adaptador(2.015 produtos)
- Ubiquitinação(1.649 produtos)
Exibir 16 mais subcategorias
Foram encontrados 66627 produtos de "Inibidores"
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INT-777
CAS:<p>INT-777 (S-EMCA) is a potent TGR5 agonist with an EC50 of 0.82 μM.</p>Fórmula:C27H46O5Pureza:99.89%Cor e Forma:SolidPeso molecular:450.65ABR-238901
CAS:<p>ABR-238901 is an oral, active S100A8/A9 blocker that inhibits the interaction of S100A8/A9 with its receptors RAGE(receptor for advanced glycation end products</p>Fórmula:C11H9BrClN3O4SPureza:98.63% - 98.71%Cor e Forma:SolidPeso molecular:394.63Moracin C
CAS:<p>Moracin C, a natural compound found in Morus mesozygia, Morus alba var.</p>Fórmula:C19H18O4Pureza:99.77% - >99.99%Cor e Forma:SolidPeso molecular:310.34WAY-600
CAS:<p>WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM; blocks mTORC1/P-S6K(T389) and mTORC2/P-AKT(S473) but not P-AKT(T308).</p>Fórmula:C28H30N8OPureza:99.88%Cor e Forma:SolidPeso molecular:494.592,4′-Dichloroacetanilide
CAS:<p>2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.</p>Fórmula:C8H7Cl2NOPureza:99.36%Cor e Forma:SolidPeso molecular:204.05AMPA receptor antagonist-3
CAS:<p>AMPA receptor antagonist-3 is an AMPA receptor antagonist.</p>Fórmula:C20H19N5O2SPureza:99.79%Cor e Forma:SolidPeso molecular:393.464A3-SC8
CAS:<p>4A3-SC8 is a modular, degradable dendrimer facilitating the extension of survival in aggressive liver cancer models through the delivery of small RNAs [1].</p>Fórmula:C75H139N3O16S4Pureza:99.87%Cor e Forma:SolidPeso molecular:1467.18PARP1/2/TNKS1/2-IN-1
CAS:<p>PARP1/2/TNKS1/2-IN-1 is a multi-target inhibitor of PARP-1, PARP-2, TNKS1 and TNKS2.PARP1/2/TNKS1/2-IN-1 has anti-tumor activity and induces apoptosis.</p>Fórmula:C35H31FN6O5Pureza:99.63%Cor e Forma:SolidPeso molecular:634.66Ranirestat
CAS:<p>Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in rats with advanced diabetic polyneuropathy</p>Fórmula:C17H11BrFN3O4Pureza:98.83% - 99.44%Cor e Forma:SolidPeso molecular:420.19PCLX-001
CAS:<p>PCLX-001, an oral NMT inhibitor, targets NMT1/NMT2 (IC50: 5/8 nM), shows anti-tumor properties, and hampers BCR signaling.</p>Fórmula:C24H30Cl2N6O2SPureza:99.6%Cor e Forma:SolidPeso molecular:537.51Varespladib methyl
CAS:<p>Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.</p>Fórmula:C22H22N2O5Pureza:99.42% - 99.97%Cor e Forma:SolidPeso molecular:394.42Lartesertib
CAS:<p>Lartesertib (ATM Inhibitor-5) is an inhibitor of the serine/threonine protein kinase ATM with potential anticancer activity and can be used to study lung cancer</p>Fórmula:C23H21FN6O3Pureza:99.9%Cor e Forma:SolidPeso molecular:448.45VH032
CAS:<p>VH032 is a VHL/HIF-1α inhibitor and PROTAC precursor targeting VHL for ubiquitination.</p>Fórmula:C24H32N4O4SPureza:99.72%Cor e Forma:SolidPeso molecular:472.6Baxdrostat
CAS:<p>Baxdrostat is an aldosterone synthase inhibitor.</p>Fórmula:C22H25N3O2Pureza:99.8%Cor e Forma:SolidPeso molecular:363.45Camonsertib
CAS:<p>Camonsertib (RP-3500) is a novel, potent and selective ATR kinase inhibitor (ATRi) that exhibits potent antitumor effects with an IC50: 1.00 nM in biochemical assays.Cost-effective and quality-assured.</p>Fórmula:C21H26N6O3Pureza:99.6% - 99.93%Cor e Forma:SolidPeso molecular:410.47Plogosertib
CAS:<p>Plogosertib (CYC140) is a PLK1 inhibitor with an IC50 value of 3 nM.Plogosertib is antiproliferative and can be used to study solid and hematologic tumors.</p>Fórmula:C34H48N8O3Pureza:99.22% - 99.85%Cor e Forma:SolidPeso molecular:616.797LE135
CAS:<p>LE135: RARα/RARβ antagonist (Ki: 1.4 μM/220 nM), favors RARβ, selective vs RARγ/RXRs; also activates TRPV1/TRPA1 (EC50s: 2.5/20 μM).</p>Fórmula:C29H30N2O2Pureza:97.94%Cor e Forma:SolidPeso molecular:438.56STAT6-IN-2
CAS:<p>STAT6-IN-2(R)-84 is a STAT6 inhibitor that inhibits the secretion of eotaxin-3 and the tyrosine phosphorylation of STAT6.</p>Fórmula:C28H31N5O2Pureza:99.67%Cor e Forma:SolidPeso molecular:469.58CB29
CAS:<p>CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).</p>Fórmula:C15H15N3O5SPureza:99.36%Cor e Forma:SolidPeso molecular:349.36Gossypolone
CAS:<p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>Fórmula:C30H26O10Pureza:96.66%Cor e Forma:SolidPeso molecular:546.52BI-3231
CAS:<p>BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.</p>Fórmula:C16H14F2N4O3SPureza:98.2%Cor e Forma:SolidPeso molecular:380.37SAFit2
CAS:<p>SAFit2 is a highly potent and selective inhibitor of fk506 binding protein 51 (FKBP51).Cost-effective and quality-assured</p>Fórmula:C46H62N2O10Pureza:98.16% - >99.99%Cor e Forma:SolidPeso molecular:802.99CINPA1
CAS:<p>CINPA1 selectively inhibits CAR with IC50 of 70 nM, useful in CAR function studies.</p>Fórmula:C23H29N3O3Pureza:99.98%Cor e Forma:SolidPeso molecular:395.49Cdk1/2 Inhibitor III
CAS:<p>Cdk1/2 Inhibitor III is a selective Cdk1/2 inhibitor with an IC50 value of 2.1 μM against CDK1/cyclin B.</p>Fórmula:C15H13F2N7O2S2Pureza:99.07%Cor e Forma:SolidPeso molecular:425.44A7132
CAS:<p>A7132 is an antibacterial agent and possesses broad and potent antibacterial activity.</p>Fórmula:C19H16F2N4O3Pureza:95.49%Cor e Forma:SolidPeso molecular:386.35Rilapladib
CAS:<p>Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating</p>Fórmula:C40H38F5N3O3SPureza:99.92%Cor e Forma:SolidPeso molecular:735.8FHT-1015
CAS:<p>FHT-1205 is a potent inhibitor (IC50 ≤ 10 nM) of SMARCA4/SMARCA2 ATPase (BRG1 and BRM).</p>Fórmula:C25H25N5O4S3Pureza:98.57%Cor e Forma:SolidPeso molecular:555.69Nrf2-IN-3
CAS:<p>Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.</p>Fórmula:C22H26N4O4SPureza:98.07%Cor e Forma:SolidPeso molecular:442.53CCT365623
CAS:<p>CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.</p>Fórmula:C18H17NO4S3Pureza:97.299% - 99.49%Cor e Forma:SolidPeso molecular:407.53GB1107
CAS:<p>GB1107 is an effective and selective Galectin-3 inhibitor with a Kd of 37 nM.</p>Fórmula:C20H16Cl2F3N3O4SPureza:98.33% - 99.87%Cor e Forma:SolidPeso molecular:522.32JNJ-42253432
CAS:<p>JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels</p>Fórmula:C28H38N4OPureza:99.98%Cor e Forma:SolidPeso molecular:446.63PARP-1-IN-4
CAS:<p>PARP-1-IN-4 is a potent PARP-1 inhibitor with potential see anti-tumor activity, and inhibition of PARP-1 may be used in cancer development.</p>Fórmula:C22H15Cl2N3O2Pureza:99.82%Cor e Forma:SolidPeso molecular:424.28Cis-N-Feruloyltyramine
CAS:<p>Cis-N-Feruloyltyramine is a naturally occurring compound found in various plants that shows cytotoxicity against the P-388 cancer cell line.</p>Fórmula:C18H19NO4Pureza:98.75%Cor e Forma:SolidPeso molecular:313.35IACS-52825
CAS:<p>IACS-52825 is a DLK inhibitor that reverses para-mechanical aberrant pain in a CIPN mouse model and can be used to study neurological disorders.</p>Fórmula:C16H13F7N4O2Pureza:99.77%Cor e Forma:SolidPeso molecular:426.29JWG-071
CAS:<p>JWG-071: First ERK5 kinase probe, BET inhibitor, 1 μM BRD4 IC, boosts ERK5 function and BRD4 selectivity.</p>Fórmula:C34H44N8O3Pureza:98.33%Cor e Forma:SolidPeso molecular:612.77LTβR-IN-1
CAS:<p>LTβR-IN-1 is a potent and selective lymphin β receptor (LTβR) inhibitor.</p>Fórmula:C18H16N4O2Pureza:98.93%Cor e Forma:SolidPeso molecular:320.35Xanthine oxidase-IN-1
CAS:<p>Xanthine oxidase-IN-1 is an effective inhibitor of xanthine oxidase with an IC50 value of 6.5 nM.</p>Fórmula:C16H8F2N2O3Pureza:97.36% - 99.22%Cor e Forma:SolidPeso molecular:314.24Dalzanemdor
CAS:<p>Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive</p>Fórmula:C27H43F3O2Pureza:98.2% - >99.99%Cor e Forma:SolidPeso molecular:456.62LNA-Adenosine
CAS:<p>LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.</p>Fórmula:C11H13N5O4Pureza:99.15%Cor e Forma:SolidPeso molecular:279.25Toxoflavin
CAS:<p>Toxoflavin (Xanthothricin) is an antagonist of transcription factor 4 (TCF4)/β-catenin complex. Toxoflavin also acts as an inhibitor of KDM4A.</p>Fórmula:C7H7N5O2Pureza:98.24% - 99.7%Cor e Forma:SolidPeso molecular:193.16CWHM-1552
CAS:<p>CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.</p>Fórmula:C22H27F2N3OPureza:99.56%Cor e Forma:SolidPeso molecular:387.47PAOPA
CAS:<p>dopamine D2 receptor modulator</p>Fórmula:C11H18N4O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:254.29GW 833972A
CAS:<p>GW 833972A: selective CB2 agonist; reduces neural depolarization and citric acid cough in animals.</p>Fórmula:C18H14Cl2F3N5OPureza:99.93%Cor e Forma:SoildPeso molecular:444.24αvβ1 integrin-IN-1
CAS:<p>αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.</p>Fórmula:C26H34N6O6SPureza:99.74% - >99.99%Cor e Forma:SolidPeso molecular:558.65Msr-Ratio
CAS:<p>Msr-Ratio is a probe for tracking MSR activity, with 375 nm excitation and 550 nm emission, used in vitro and in cells.</p>Fórmula:C18H14O3SPureza:98.93%Cor e Forma:SolidPeso molecular:310.37MCT1-IN-3
CAS:<p>MCT1-IN-3 is a monocarboxylate transporter 1 (MCT1) inhibitor.</p>Fórmula:C22H19N3O4Pureza:99.35%Cor e Forma:SoildPeso molecular:389.4Iptacopan
CAS:<p>Iptacopan (LNP023) is an inhibitor with high affinity to factor B, with a KD value of 7.9 nM and an IC50 value of 10 nM. Cost-effective and quality-assured.</p>Fórmula:C25H30N2O4Pureza:99.07% - >99.99%Cor e Forma:SolidPeso molecular:422.52Calcium channel-modulator-1
CAS:<p>Calcium channel-modulator-1 is a calcium channel-modulator (IC50:0.8 μM) with specialisation to block aortic constriction.</p>Fórmula:C26H24Cl2N2O7SPureza:99.95%Cor e Forma:SolidPeso molecular:579.45h-NTPDase-IN-2
CAS:<p>h-NTPDase-IN-2 is a broad-spectrum NTPDase inhibitor that inhibits multiple h-NTPDas isoforms.</p>Fórmula:C19H16N4SPureza:99.58%Cor e Forma:SolidPeso molecular:332.42Filibuvir
CAS:<p>Filibuvir (PF-00868554) inhibits HCV polymerase genotypes 1a/1b, EC50s 59 nM.</p>Fórmula:C29H37N5O3Pureza:99.28% - >99.99%Cor e Forma:SolidPeso molecular:503.64
