Inibidores
Os inibidores são moléculas que se ligam a enzimas, receptores ou outras proteínas para reduzir ou bloquear sua atividade biológica. Esses compostos são amplamente utilizados em pesquisas para estudar vias biológicas, entender mecanismos de doenças e desenvolver medicamentos terapêuticos. Os inibidores desempenham um papel crucial no tratamento de várias doenças, incluindo câncer, doenças cardiovasculares e infecções. Na CymitQuimica, oferecemos uma ampla gama de inibidores de alta qualidade para apoiar sua pesquisa em bioquímica, biologia celular e desenvolvimento farmacêutico.
Subcategorias de "Inibidores"
- Angiogénese(2.523 produtos)
- Apoptose(5.792 produtos)
- Ciclo celular/Ponto de verificação(4.449 produtos)
- Cromatina/Epigenética(2.238 produtos)
- Sinalização Citoesquelética(1.383 produtos)
- Dano de DNA/Reparo de DNA(2.825 produtos)
- Endocrinologia/Hormónios(3.507 produtos)
- Enzima(3.640 produtos)
- GPCR/Proteína-G(8.333 produtos)
- Imunologia e Inflamação(3.526 produtos)
- Vírus da Influenza(296 produtos)
- Sinalização JAK/STAT(404 produtos)
- Sinalização MAPK(1.202 produtos)
- Transportador de Membranas/Canal Iónico(2.790 produtos)
- Metabolismo(9.448 produtos)
- Microbiologia/Virologia(6.981 produtos)
- Neurociência(9.926 produtos)
- Outros inibidores(37.926 produtos)
- Oxidação-Redução(41 produtos)
- Sinalização PI3K/Akt/mTOR(1.400 produtos)
- Proteases/Proteassoma(1.597 produtos)
- Células - tronco e Derivados(831 produtos)
- Tirosina Quinase/Adaptador(2.016 produtos)
- Ubiquitinação(1.650 produtos)
Exibir 16 mais subcategorias
Foram encontrados 66641 produtos de "Inibidores"
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Glutaminyl Cyclase Inhibitor 4
CAS:<p>Glutaminyl Cyclase Inhibitor 4 is a potent, selective glutaminyl cyclase (QC) inhibitor (IC50: 6.1 nM). It is a potent anti-Alzheimer’s agent.</p>Fórmula:C22H33N5O3Pureza:98%Cor e Forma:SolidPeso molecular:415.53Erythrityl Tetranitrate
CAS:<p>Erythrityl Tetranitrate, a vasodilator similar to nitroglycerin, was first in "sustained release" tablets; may cause "nitro headache."</p>Fórmula:C4H6N4O12Cor e Forma:SolidPeso molecular:302.11BET-IN-15
CAS:<p>BET-IN-15 (compound 1) is a potent, orally active inhibitor of BET, demonstrating inhibitory IC50 values of 0.64 nM for BRD4-BD1 and 0.25 nM for BRD4-BD2.</p>Fórmula:C21H18F2N4O3SPureza:98%Cor e Forma:SolidPeso molecular:444.45Ref: TM-T79167
Produto descontinuadoLp-PLA2-IN-15
CAS:<p>Lp-PLA2-IN-15 (example 2) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential application in Alzheimer's disease research [1].</p>Fórmula:C22H17F5N4O3Pureza:98%Cor e Forma:SolidPeso molecular:480.39Ref: TM-T79075
Produto descontinuadoBChE-IN-17
CAS:<p>BChE-IN-17 (compound 6n) is a potent, selective inhibitor of butyrylcholinesterase (BChE), demonstrating inhibitory half-maximal inhibitory concentrations (</p>Fórmula:C23H23BrN2O4S2Cor e Forma:SolidPeso molecular:535.47HBV-IN-34
CAS:<p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>Fórmula:C21H19F2N7Pureza:98%Cor e Forma:SolidPeso molecular:407.42Ref: TM-T79469
Produto descontinuadoPPARγ-IN-2
CAS:<p>"PPARγ-IN-2 (Compound 5a), a PPARγ inhibitor, exhibits an EC50 of 0.106 μM in inhibiting TG accumulation in 3T3-L1 preadipocytes.</p>Fórmula:C19H21N5OPureza:98%Cor e Forma:SolidPeso molecular:335.4Ref: TM-T79678
Produto descontinuadoPazinaclone
CAS:<p>Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.</p>Fórmula:C25H23ClN4O4Pureza:97.79% - 99.07%Cor e Forma:SolidPeso molecular:478.93SR14150
CAS:<p>SR14150 is a partial agonist of high-affinity NOP receptor.</p>Fórmula:C21H30N2OPureza:98%Cor e Forma:SolidPeso molecular:326.48SB251023
CAS:<p>SB251023 is an agonist of β3-adrenoceptor.</p>Fórmula:C28H34NO6PCor e Forma:SolidPeso molecular:511.55AMPK activator C2
CAS:<p>AMPK activator C2 is an AMPK allosteric activator.</p>Fórmula:C7H6NO6PPureza:98%Cor e Forma:SolidPeso molecular:231.1Radafaxine hydrochloride
CAS:<p>Radafaxine hydrochloride is an inhibitor of DAT and NET transporters, and nAChR family modulator.</p>Fórmula:C13H19Cl2NO2Pureza:98%Peso molecular:292.2(S)-Coriolic acid
CAS:<p>(S)-Coriolic acid, a 15-LOX metabolite and signaling molecule, modulates cell growth, tumor adhesion, receptor expression, and can cause mitochondrial damage.</p>Fórmula:C18H32O3Pureza:97.67% - 98.04%Cor e Forma:SolidPeso molecular:296.44H 35-25
CAS:<p>H 35-25 is a beta 2-antagonist.</p>Fórmula:C13H21NOCor e Forma:SolidPeso molecular:207.31Trimetoquinol HCl hydrate
CAS:<p>Trimetoquinol hydrochloride possesses differential and selective beta-adrenergic properties.</p>Fórmula:C19H26ClNO6Cor e Forma:SolidPeso molecular:399.87CH-100
CAS:<p>CH-100 is a Chinese herbal medicine previously used in the treatment of human hepatitis C.</p>Fórmula:C14H22ClNO3Cor e Forma:SolidPeso molecular:287.78JAK2-IN-9
CAS:<p>Compound A8, known as JAK2-IN-9, is a selective JAK2 inhibitor with an IC50 of 5 nM.</p>Fórmula:C20H24N6O2SPureza:98%Cor e Forma:SolidPeso molecular:412.51Ref: TM-T79581
Produto descontinuadoPAD4-IN-2
CAS:<p>PAD4-IN-2 (compound 5i) is a PAD4 inhibitor with an IC50 value of 1.94 μM, shown to suppress tumor growth in mice through specific inhibition of the PAD4-H3cit-</p>Fórmula:C20H23BClN7O6Cor e Forma:SolidPeso molecular:503.7Mavodelpar free base
CAS:<p>Mavodelpar free acid (REN001 free acid) is an selective agonist of PPARδ.</p>Fórmula:C31H30FNO5Pureza:98%Cor e Forma:SolidPeso molecular:515.57Benzovindiflupyr
CAS:<p>Benzovindiflupyr: a fungicide that inhibits SDH (IC50=5.2nM), halts S. sclerotiorum growth (EC50=0.011μg/ml), and protects crops like eggplants.</p>Fórmula:C18H15Cl2F2N3OCor e Forma:SolidPeso molecular:398.23anti-TNBC agent-2
CAS:<p>Anti-TNBC agent-2 (3j), a purine derivative, acts as an anti-triple negative breast cancer (TNBC) therapeutic.</p>Fórmula:C28H37ClFN7OPureza:98%Cor e Forma:SolidPeso molecular:542.09Ref: TM-T79699
Produto descontinuadoPSB-6426
CAS:<p>PSB-6426 is the first potent and selective human nucleoside triphosphate diphosphohydrolase-2 inhibitor.</p>Fórmula:C22H29N4O10PPureza:98%Cor e Forma:SolidPeso molecular:540.46PKUMDL-LTQ-301
CAS:PKUMDL-LTQ-301 is a potent inhibitor of HipA toxin. PKUMDL-LTQ-301 also inhibits E. coli persistence.Fórmula:C30H28N2O4Pureza:98%Cor e Forma:SolidPeso molecular:480.55Saxitoxinol
CAS:<p>Saxitoxinol is an analog of saxitoxin, a known voltage-gated sodium channel blocker.</p>Fórmula:C10H17N7O3Pureza:98%Cor e Forma:SolidPeso molecular:283.29Ref: TM-T68748
Produto descontinuadoMEN11467
CAS:<p>MEN11467 is a novel, orally available, potent and selective peptidomimetic tachykinin NK 1 receptor antagonist for the study of acute colon cancer.</p>Fórmula:C38H40N4O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:600.75CK176
CAS:<p>CK176 is an HIV-1 inhibitor, 11x more effective than I-XW-053 in human PBMCs.</p>Fórmula:C21H12IN3O2Pureza:98%Cor e Forma:SolidPeso molecular:465.24Cebranopadol ((1α,4α)stereoisomer)
CAS:<p>Cebranopadol ((1α,4α)stereoisomer) is a stereoisomer of cebranopadol which is a potent ORL-1 agonist.</p>Fórmula:C24H27FN2OPureza:98%Cor e Forma:SolidPeso molecular:378.48Phenazolam
CAS:<p>Phenazolam is an analytical reference standard categorized as a benzodiazepine. [1] This product is intended for research and forensic applications.</p>Fórmula:C17H12BrClN4Cor e Forma:SolidPeso molecular:387.66HPK1-IN-18
CAS:<p>HPK1-IN-18: Potent, specific inhibitor of HPK1, a MAP4K enzyme, for cancer research and treatment.</p>Fórmula:C24H24N4Cor e Forma:LiquidPeso molecular:368.47AKOS-22
CAS:<p>AKOS-22: potent VDAC1 inhibitor, Kd=15.4 μM; prevents mitochondrial dysfunction and apoptosis.</p>Fórmula:C22H21ClF3N3O3Pureza:98%Cor e Forma:SolidPeso molecular:467.87IDX-375
CAS:<p>IDX-375, a HCV NS5B polymerase inhibitor, is used potentially for the treatment of HCV infection.</p>Fórmula:C29H50N5O7PSPureza:98%Cor e Forma:SolidPeso molecular:643.78Bromadoline maleate
CAS:<p>Bromadoline is an opioid analgesic selective for the μ-opioid receptor.</p>Fórmula:C19H25BrN2O5Pureza:98%Cor e Forma:SolidPeso molecular:441.322Ceronapril
CAS:<p>Ceronapril (SQ 29852) is an orally active and potent angiotensin-converting enzyme (ACE) inhibitor (IC50 : 36 nM) for the study of dementia and hypertension.</p>Fórmula:C21H33N2O6PPureza:97.94%Cor e Forma:SolidPeso molecular:440.47Fotemustine
CAS:<p>Fotemustine: antineoplastic, chloroethylates DNA, blocks synthesis, causes cell arrest/apoptosis, lipophilic, crosses blood-brain barrier.</p>Fórmula:C9H19ClN3O5PCor e Forma:SolidPeso molecular:315.69KP372-1
CAS:<p>KP372-1, an Akt inhibitor, blocks PI3K signaling, arrests cell growth, and triggers apoptosis in head/neck squamous cell carcinoma.</p>Fórmula:C20H8N12O2Cor e Forma:SolidPeso molecular:448.36Lp-PLA2-IN-16
CAS:<p>Lp-PLA2-IN-16 (Example 1) is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with potential applications in Alzheimer's disease research [1].</p>Fórmula:C22H17F5N4O3Pureza:98%Cor e Forma:SolidPeso molecular:480.39Ref: TM-T79076
Produto descontinuadoFostedil
CAS:<p>Fostedil enhances heart function, maintains blood flow during partial/total coronary occlusions, and lowers aortic pressure.</p>Fórmula:C18H20NO3PSPureza:98%Cor e Forma:SolidPeso molecular:361.4Lp-PLA2-IN-12
CAS:<p>Lp-PLA2-IN-12 (compound 19), an Lp-PLA2 inhibitor, is utilized in researching neurodegenerative diseases including Alzheimer's disease (AD), glaucoma, age-</p>Fórmula:C24H23F2N5O3Pureza:98%Cor e Forma:SolidPeso molecular:467.47Ref: TM-T79010
Produto descontinuadoFGFR1 inhibitor-10
CAS:<p>FGFR1 inhibitor-10 (Compound 4i), with an IC50 of 28 nM, effectively inhibits FGFR1 phosphorylation.</p>Fórmula:C26H30F3N7O2SPureza:98%Cor e Forma:SolidPeso molecular:561.62Ref: TM-T79686
Produto descontinuadoYM 298198 Hydrochloride
CAS:<p>YM 298198 HCl: non-competitive mGlu1 antagonist, Ki=19 nM. Inactive on mGlu2-7, stronger than CPCCOEt.</p>Fórmula:C18H22N4OSCor e Forma:SolidPeso molecular:342.46(E)-Crotylbarbital
CAS:<p>(E)-Crotylbarbital, a Crotylbarbital isomer, is a sedative with hypnotic, anticonvulsant properties, aiding sleep and mental stability.</p>Fórmula:C10H14N2O3Pureza:99.94%Cor e Forma:SolidPeso molecular:210.23DprE1-IN-8
CAS:<p>DprE1-IN-8 is a potent inhibitor of DprE1, exhibiting an IC50 of less than 0.75 μM.</p>Fórmula:C19H12F3N5O4SPureza:98%Cor e Forma:SolidPeso molecular:463.39Ref: TM-T79628
Produto descontinuadoDPX-3778
CAS:<p>DPX-3778, a triethanolamine salt, boosts tobacco callus growth 4-5x at 0.124-2.48 μM and slows aging with IAA and kinetin.</p>Fórmula:C16H23ClN4O6Cor e Forma:SolidPeso molecular:402.83anti-TNBC agent-3
CAS:<p>Anti-TNBC agent-3 (compound 3g) is a compound that induces apoptosis and possesses anti-cancer cell proliferation properties.</p>Fórmula:C29H39F2N7OCor e Forma:SolidPeso molecular:539.66Questiomycin A derivatives 18 TFA
<p>Questiomycin A derivative 18 TFA exhibits antibacterial, anticancer properties and inhibits GRP78.</p>Fórmula:C16H12F3N3O5Pureza:98.45%Cor e Forma:SoildPeso molecular:383.07Ref: TM-T67717L
Produto descontinuadoEGFR-IN-82
CAS:<p>EGFR-IN-82 (Compound 8a) is a potent, orally active inhibitor of EGFR, exhibiting IC50 values of 0.09 nM for EGFR L858R/T790M/C797S and 0.06 nM for EGFR Del19/</p>Fórmula:C32H41BrN9O2PPureza:98%Cor e Forma:SolidPeso molecular:694.6Ref: TM-T78788
Produto descontinuadoBTK-IN-27
CAS:<p>BTK-IN-27 (example 8), a potent BTK inhibitor with an IC50 of 0.2 nM, demonstrates anti-proliferative effects in TMD8 cells with an IC50 of less than 5 nM.</p>Fórmula:C31H35N7O2Pureza:98%Cor e Forma:SolidPeso molecular:537.66Xilmenolone
CAS:<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Fórmula:C26H37N3O2Pureza:98%Cor e Forma:SolidPeso molecular:423.59Ref: TM-T78670
Produto descontinuadoTrkB-IN-1
CAS:<p>TrkB-IN-1 is a potent, orally active agonist of the TrkB receptor, with favorable pharmacokinetic (PK) properties.</p>Fórmula:C19H16N2O6Pureza:98%Cor e Forma:SolidPeso molecular:368.34VISTA-IN-2
CAS:<p>VISTA-IN-2 (Compound 1) is a V-domain Ig suppressor of T-cell activation (VISTA) inhibitor that promotes the degradation of VISTA in cells via autophagy,</p>Fórmula:C23H23N3OPureza:98%Cor e Forma:SolidPeso molecular:357.45Ref: TM-T79653
Produto descontinuado
