Proteínas de checkpoint imunológico
As proteínas de ponto de verificação imunológica são moléculas que geram sinais co-estimuladores ou co-inibidores durante as respostas imunológicas, relevantes na pesquisa de imunoterapia contra o câncer. Essas proteínas são alvos para terapias projetadas para modular o sistema imunológico, aumentando sua capacidade de reconhecer e destruir células cancerosas, enquanto minimizam os danos aos tecidos normais. Na CymitQuimica, oferecemos uma ampla gama de proteínas de ponto de verificação imunológica para apoiar seus esforços de pesquisa e desenvolvimento em imunoterapia.
Foram encontrados 155 produtos de "Proteínas de checkpoint imunológico"
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B7-H4 Protein, Mouse, Recombinant (His), Biotinylated
Expression system: HEK293 Cells
Length: 29-256, Partial
Activity: Not TestedCor e Forma:Lyophilized PowderPeso molecular:26.6 kDa (predicted); 50.2 kDa (reducing contition)FGL1 Protein, Human, Recombinant (hFc)
FGL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 Cells. The accession number is Q08830.
Cor e Forma:Lyophilized PowderPeso molecular:~61.8 kDa (Reducing conditions)Ref: TM-TMPS-00034
1mg3.220,00€5µg77,00€10µg110,00€20µg173,00€50µg343,00€100µg474,00€200µg838,00€500µg1.795,00€PVRIG Protein, Human, Recombinant (aa 41-172, hFc)
Expression system: HEK293 Cells
Length: 41-172, Partial
Activity: ELISACor e Forma:Lyophilized PowderPeso molecular:40.5 kDa (predicted); 50.8 kDa (reducing contition, due to glycosylation)Ref: TM-TMPY-07164
1mg4.050,00€5µg71,00€10µg102,00€20µg160,00€50µg309,00€100µg613,00€200µg888,00€500µg1.980,00€CD200R Protein, Human, Recombinant (His)
CD200R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:SDS-PAGE: 98.3%; SEC-HPLC: 96.8%Cor e Forma:Lyophilized PowderPeso molecular:28.2 kDa (predicted); 50-60 kDa (reducing condition, due to glycosylation)CD200R1/CRTR2 Protein, Human, Recombinant (hFc)
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cellPureza:> 95% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 95% as determined by Bis-Tris PAGE > 95% as determined by HPLCCor e Forma:Lyophilized PowderPeso molecular:53.7 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.CD200R Protein, Mouse, Recombinant (His)
CD200R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:24.21 kDa (Predicted); 55-65 kDa (Due to glycosylation)Ref: TM-TMPY-01665
1mg4.078,00€5µg71,00€10µg101,00€20µg166,00€50µg324,00€100µg627,00€200µg954,00€500µg2.008,00€Siglec-9 Protein, Human, Recombinant (His & hFc)
Siglec-9 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:64.13 kDa (predicted); 97.5 kDa (reducing conditions)Ref: TM-TMPY-06966
5µg79,00€10µg110,00€20µg177,00€50µg359,00€100µg623,00€200µg1.080,00€500µg2.637,00€TIM-3/KIM-3/HAVCR2 Protein, Human, Recombinant (hFc)
Expression System: HEK293 Cells
Length: 22-200, Extracellular Domain
Activity: ELISACor e Forma:Lyophilized PowderPeso molecular:60~65 kDa (Reducing conditions)Ref: TM-TMPS-00135
1mg3.220,00€5µg113,00€10µg180,00€20µg298,00€50µg590,00€100µg873,00€200µg1.293,00€500µg2.167,00€CD200R1/CRTR2 Protein, Cynomolgus, Recombinant (His)
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cellCor e Forma:Lyophilized PowderPeso molecular:28.09 kDa (predicted). Due to glycosylation, the protein migrates to 67-77 kDa based on Tris-Bis PAGE result.Siglec-9 Protein, Human, Recombinant (His)
Siglec-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:37.48 kDa (predicted); 61.92 kDa (reducing conditions)Ref: TM-TMPY-06847
5µg96,00€10µg141,00€20µg224,00€50µg449,00€100µg772,00€200µg1.378,00€500µg3.412,00€CD200R Protein, Human, Recombinant (His & hFc)
CD200R Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:54.9 kDa (predicted); 90-100 kDa (reducing condition, due to glycosylation)CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi), Biotinylated
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cellCor e Forma:Lyophilized PowderPeso molecular:29.7 kDa (predicted). Due to glycosylation, the protein migrates to 52-70 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00623
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€Siglec-9 Protein, Human, Recombinant (His & Avi), Biotinylated
Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells.Cor e Forma:Lyophilized PowderPeso molecular:38.9 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00287
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€Siglec-9 Protein, Human, Recombinant (hFc)
Siglec-9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Cor e Forma:Lyophilized PowderPeso molecular:90-120 KDa (reducing condition)Ref: TM-TMPJ-00550
1mg2.457,00€5µg74,00€10µg108,00€20µg164,00€50µg279,00€100µg479,00€200µg827,00€500µg1.710,00€CD200R1/CRTR2 Protein, Human, Recombinant (His & Avi)
CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cellCor e Forma:Lyophilized PowderPeso molecular:29.7 kDa (predicted). Due to glycosylation, the protein migrates to 52-68 kDa based on Tris-Bis PAGE result.CD200R1/CRTR2 Protein, Human, Recombinant (His)
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein.Cor e Forma:Lyophilized PowderPeso molecular:50-80 KDa (reducing condition)Ref: TM-TMPJ-00233
1mg2.457,00€5µg63,00€10µg90,00€20µg138,00€50µg245,00€100µg437,00€200µg782,00€500µg1.710,00€Siglec-9 Protein,Human, Recombinant(aa 18-348, His)
Siglec-9 Protein,Human, Recombinant(aa 18-348, His) is expressed in HEK293 mammalian cells with C-6xHis tag.Cor e Forma:Lyophilized PowderPeso molecular:55-90 KDa (reducing condition)Ref: TM-TMPJ-00551
1mg2.673,00€5µg104,00€10µg170,00€20µg263,00€50µg490,00€100µg732,00€200µg1.071,00€500µg1.863,00€CD200R Protein, Mouse, Recombinant (His & hFc)
CD200R Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:51.3 kDa (predicted); 90-100 kDa (reducing condition, due to glycosylation)Siglec-9 Protein, Human, Recombinant (His & Avi)
Siglec-9 is a sialic-acid-binding lectin expressed predominantly on myeloid cells.Cor e Forma:Lyophilized PowderPeso molecular:38.9 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.TIGIT Dimer Protein, Human, Recombinant (Avi & His), Biotinylated
Expression system: HEK293 Cells
Length: 22-141, Extracellular Domain
Activity: ELISACor e Forma:Lyophilized PowderPeso molecular:30.63 kDa (predicted); 39.3 kDa (reducing contition)
