Sistema complementar
O sistema complemento é uma parte crucial da resposta imunológica, consistindo em uma série de pequenas proteínas que melhoram a capacidade dos anticorpos e das células fagocíticas de eliminar patógenos de um organismo. Essas proteínas trabalham juntas para opsonizar patógenos, induzir respostas inflamatórias e lisar diretamente as membranas dos patógenos, desempenhando um papel vital na imunidade inata e na função imunológica geral. Na CymitQuimica, fornecemos proteínas de alta qualidade do sistema complemento para apoiar seus estudos imunológicos e pesquisas clínicas.
Foram encontrados 156 produtos de "Sistema complementar"
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SB290157 trifluoroacetate
CAS:<p>SB290157 trifluoroacetate is a potent and selective antagonist of C3a receptor(IC50 of 200 nM).</p>Fórmula:C24H29F3N4O6Pureza:98.93% - 99.89%Cor e Forma:SolidPeso molecular:526.51Lampalizumab
CAS:<p>Lampalizumab (RG 7417) is a humanized monoclonal antibody targeting Factor D, which can be used in cardiovascular disease research.</p>Pureza:>95%Cor e Forma:LiquidPeso molecular:46.96 (kDa)Vesencumab
CAS:<p>Vesencumab (MNRP-1685A) is an IG1 antibody targeting NRP-1 with anti-angiogenic and anti-tumor activity. Vesencumab can be used to study solid tumors.</p>Pureza:99.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 99.2% (SDS-PAGE); 96.6% (SEC-HPLC)Cor e Forma:LiquidVilobelimab
CAS:<p>Vilobelimab (CaCP-29, IFX-1), a monoclonal antibody, inhibits C5a to reduce inflammation and is researched in sepsis and COVID-19 studies.</p>Pureza:99% (SDS-PAGE); 98.9% (SEC-HPLC) - 99% (SDS-PAGE); 98.9% (SEC-HPLC)Cor e Forma:LiquidSutimlimab
CAS:<p>Sutimlimab: monoclonal antibody, inhibits complement protein C1, treats cold agglutinin-induced hemolysis.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:144.8 kDaTesidolumab
CAS:<p>Tesidolumab, a fully human IgG1/λ anti-C5 monoclonal antibody, inhibits crovalimab and C5, preventing membrane attack complex formation.</p>Pureza:99.72% (SEC-HPLC) - > 95%Cor e Forma:LiquidPeso molecular:142 kDa (average)Ravulizumab
CAS:<p>Ravulizumab (ALXN1210) is a humanized antibody for blocking complement activation, treating PNH, aHUS, and myasthenia gravis.</p>Pureza:> 95%Cor e Forma:LiquidPeso molecular:145.80 kDaCyclosporin A
CAS:<p>Cyclosporin A is a Calcineurin Inhibitor Immunosuppressant, and a Cytochrome P450 3A4 Inhibitor, and P-Glycoprotein Inhibitor.</p>Fórmula:C62H111N11O12Pureza:99.00% - 99.92%Cor e Forma:White PowderPeso molecular:1202.61Avdoralimab
CAS:<p>Avdoralimab (IPH 5401) is a humanized monoclonal antibody targeting complement C5a receptor 1 (C5aR1).</p>Pureza:>95%Cor e Forma:LiquidDexamethasone
CAS:<p>Dexamethasone: a glucocorticoid agonist; modulates IL receptors; reduces inflammatory miRNA-155 exosomes in macrophage responses.</p>Fórmula:C22H29FO5Pureza:98% - 99.91%Cor e Forma:Crystals From Ether (Ntp 1992)Peso molecular:392.46EG01377 2HCl
CAS:<p>EG01377 2HCl is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1) with a Kd value of 1.32 μM and an IC50 value of 609 nM for both EG01377</p>Fórmula:C26H32Cl2N6O6S2Pureza:98.91%Cor e Forma:SoildPeso molecular:659.6ARC186
<p>ARC186 is a highly potent aptamer that serves as a complement inhibitor by blocking the convertase-catalyzed activation of C5.</p>Cor e Forma:SolidPeso molecular:120702.76PIC1 PA TFA
<p>PIC1 PATFA is the trifluoroacetate form of PIC1 PA. PIC1 PA TFA is a peptide composed of 15 amino acids and serves as an effective PIC1 analog capable of inhibiting complement activation mediated by the classical pathway.</p>Fórmula:C71H123N19O21S2·xC2HF3O2Cor e Forma:SolidPMX 205
CAS:<p>PMX 205 is an effective complement antagonist of the C5a receptor.</p>Fórmula:C45H62N10O6Pureza:98%Cor e Forma:SolidPeso molecular:839.04Claseprubart
CAS:<p>Claseprubart is a monoclonal antibody that targets human complement C1s. It specifically binds to complement C1s, inhibiting the activation of the complement system and exerting immunosuppressive effects. Claseprubart shows potential for research in autoimmune diseases and inflammation-related conditions.</p>Cor e Forma:LiquidC1s-IN-1 trihydrochloride
CAS:<p>C1s-IN-1 trihydrochloride (Compound A1) is a selective inhibitor of C1s protease with a Ki of 5.8 μM. This compound inhibits the cleavage of C2 by C1s with an IC50 of 85 μM and prevents activation of the classical pathway, with an IC50 of 22 μM. Additionally, C1s-IN-1 trihydrochloride acts as a competitive inhibitor of thrombin, exhibiting a Ki of 51.2 μM.</p>Fórmula:C16H22Cl3N5Cor e Forma:SolidPeso molecular:390.74NH2-C6-ARC186
<p>NH2-C6-ARC186 is a derivative of the aptamer ARC186, featuring an NH2-C6 moiety that enables coupling to various peptides or molecules.</p>Pureza:98%Cor e Forma:SolidPeso molecular:12881C3a (70-77)
CAS:<p>C3a (70-77) is an octapeptide corresponding to the COOH terminus of C3a.</p>Fórmula:C35H61N13O10Pureza:98%Cor e Forma:SolidPeso molecular:823.94L-156,602
CAS:<p>L-156,602 has a wide range of applications in life science related research.</p>Fórmula:C38H64N8O13Cor e Forma:SolidPeso molecular:840.973AMY-101
CAS:<p>AMY-101 TFA is a C3 complement inhibitor with high affinity (KD: 0.5 nM) and promising anti-inflammatory effects in severe COVID-19.</p>Fórmula:C83H117N23O18S2Pureza:98%Cor e Forma:SolidPeso molecular:1789.11ATWLPPR Peptide TFA
<p>ATWLPPR Peptide TFA inhibits neuropilin-1 and VEGF165-NRP-1 binding; may reduce diabetic retinal damage.</p>Fórmula:C42H62F3N11O11Pureza:98%Cor e Forma:SolidPeso molecular:954CP-447697
CAS:<p>CP-447697, a lipophilic C5a receptor antagonist, exhibits an IC50 of 31 nM. It is utilized in inflammation research.</p>Fórmula:C29H26ClF2N3O2SPureza:99.90%Cor e Forma:SoildPeso molecular:554.05CP-289
CAS:<p>CP-289 is a potent C5a receptor antagonist with IC50 of 1 μM.</p>Fórmula:C30H35ClN2O2Pureza:99.97%Cor e Forma:SoildPeso molecular:491.06Human Immunoglobulin M
<p>Human Immunoglobulin M (IgM) is an antibody secreted by the adaptive immune system in response to foreign antigens. It is a primary type of immunoglobulin released into circulation during the early stages of the primary antibody response. Human Immunoglobulin M forms a pentamer comprising five IgG equivalents, with 10 Fab fragments, allowing for 10 antigen binding sites. Additionally, Human Immunoglobulin M acts as a complement (complement) activator.</p>Cor e Forma:Odour SolidFactor B-IN-1
CAS:<p>Factor B-IN-1 is a Factor B inhibitor.</p>Fórmula:C19H16N4O2Cor e Forma:SolidPeso molecular:332.3559Olendalizumab
CAS:<p>Olendalizumab (ALXN1007) is a humanized antibody targeting C5a for research on COVID-19-related inflammation.</p>Cor e Forma:Liquid3-O-(2'E,4'Z-Decadienoyl)ingenol
<p>3-O-(2'E,4'Z-Decadienoyl)ingenol is a useful organic compound for research related to life sciences and the catalog number is T124104.</p>Fórmula:C30H42O6Cor e Forma:SolidPeso molecular:498.66Vemircopan
CAS:<p>Vemircopan is a complement factor D inhibitor.</p>Fórmula:C29H28BrN7O3Cor e Forma:SolidPeso molecular:602.493PMX 205 Trifluoroacetate
<p>PMX 205 Trifluoroacetate is a potent complement C5a receptor ( C5aR ; CD88 ) antagonist.</p>Fórmula:C47H63F3N10O8Cor e Forma:SolidPeso molecular:953.06PMX-53
CAS:<p>PMX-53: MrgX2 agonist; C5aR antagonist; lessens atherosclerotic lesions & metastasis in mice; blocks rat hypernociception.</p>Fórmula:C47H65N11O7Pureza:98%Cor e Forma:SolidPeso molecular:896.09JPE-1375
CAS:<p>JPE-1375: a C5aR1 antagonist, blocks leukocyte mobilization (EC50=6.9 µM), lowers TNF in mice (EC50=4.5 µM), useful for autoimmune/inflammation research.</p>Fórmula:C49H63FN10O9Cor e Forma:SolidPeso molecular:955.08TLQP-21
CAS:<p>TLQP 21, a VGF-derived peptide, guards CGCs against apoptosis and combats early diet-induced diabetes by boosting energy spend.</p>Fórmula:C107H170N40O26Pureza:98%Cor e Forma:SolidPeso molecular:2432.75Certepetide
CAS:<p>Certepetide, or iRGD, is a cyclic peptide that enhances tumor penetration and researches solid cancers.</p>Fórmula:C37H60N14O14S2Cor e Forma:SolidPeso molecular:989.09Compstatin TFA
<p>Compstatin TFA: 13-residue cyclic peptide, inhibits primate complement C3, species-specific, protease-resistant, IC50=63μM (classical), 12μM (alternative).</p>Fórmula:C68H100F3N23O19S2Cor e Forma:SolidPeso molecular:1664.79Pegcetacoplan acetate
<p>Pegcetacoplan acetate is a pegylated complement C3 inhibitory peptide that functions by binding to complement component 3 (C3) and its activation fragment C3b. This compound is utilized in the study of complement-mediated diseases, including age-related macular degeneration, C3 glomerulopathy, geographic atrophy (GA), and autoimmune hemolytic anemia.</p>Cor e Forma:Odour SolidComplement C1s-IN-1
CAS:<p>Complement C1s-IN-1 is a selective inhibitor of complement C1s，oral and brain penetrable, inhibit human serum-induced formation of membrane attack complexes</p>Fórmula:C22H20F2N6OPureza:97.77%Cor e Forma:SoildPeso molecular:422.43Pozelimab
CAS:<p>Pozelimab (REGN 3918) is a humanized antibody targeting component 5 (C5), used for research on Pozelimab disease.</p>Pureza:98.94% (SEC-HPLC) - 98.94% (SEC-HPLC)Cor e Forma:LiquidtLyP-1 peptide
CAS:<p>tLyP-1 peptide is an NRP-1 targeting peptide with an IC50 of 4 μM, and its amino acid sequence is CGNKRTR. It can specifically bind to NRP-1 to target tumor cells.</p>Fórmula:C31H59N15O10SCor e Forma:SolidPeso molecular:833.96CK3 peptide
CAS:<p>CK3 peptide is an NRP-1-targeting peptide with the amino acid sequence CLKADKAKC. It specifically binds to NRP-1 to target breast cancer cells. Single-photon emission computed tomography (SPECT) and near-infrared fluorescence (NIRF) imaging demonstrate that CK3 peptide significantly accumulates in xenograft tumors in nude mice. CK3 peptide is applicable for molecular imaging studies of breast cancer.</p>Fórmula:C40H72N12O12S2Cor e Forma:SolidPeso molecular:977.203Vensobafusp alfa
CAS:<p>Vensobafusp alfa (KP-104) is a fusion protein composed of an IgG4 monoclonal antibody targeting complement protein C5, combined with the domains 1-5 of complement factor H (FH1-5). It exhibits anti-inflammatory and immunomodulatory properties. The isotype control for Vensobafusp alfa can be referred to as human IgG4(S228P) kappa.</p>Cor e Forma:LiquidZilucoplan (PEG2)
<p>Zilucoplan(PEG2) is a derivative of Zilucoplan where the linker component has been substituted with PEG2 instead of PEG24. This compound acts as an effective inhibitor of complement component 5 (C5).</p>Fórmula:C128H190N24O33Cor e Forma:SolidPeso molecular:2593.02AMY-101 TFA
CAS:<p>AMY-101 TFA is an inhibitor of complement C3 and an immunomodulator, gingivitis and periodontitis. reduces inflammation and lowers levels of MMP-8 and MMP-9</p>Fórmula:C85H118F3N23O20S2Cor e Forma:SolidPeso molecular:1903.11Factor B-IN-5
CAS:<p>Factor B-IN-5 is a complement factor B inhibitor, which can be used to study immune-related diseases.</p>Fórmula:C27H32N2O4Pureza:98.19%Cor e Forma:SoildPeso molecular:448.55C5aR2 agonist P32 acetate
<p>C5aR2 agonist P32 acetate (Ac-RHYPYWR-OH), a selective agonist for C5aR2, has been shown to induce various immunomodulatory activities both in vitro and in vivo. It modulates cell signaling via the downregulation of C5aR1-mediated pathways and can also function independently of C5aR1.</p>Fórmula:C54H70N16O11·xC2H4O2Cor e Forma:SolidPeso molecular:1119.23 (free base)Greziprubart
<p>Greziprubart is a humanized IgG1κ monoclonal antibody that targets C5a, with HumanIgG1kappa, Isotype Control serving as its corresponding isotype control.</p>Cor e Forma:Odour Liquid3-Phenoxybenzaldehyde
CAS:<p>3-Phenoxybenzaldehyde is a complement (classical pathway) inhibitor with IC50 of 1388μM.</p>Fórmula:C13H10O2Pureza:99.01%Cor e Forma:SolidPeso molecular:198.22MBL2 Protein, Mouse, Recombinant
<p>Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix.</p>Cor e Forma:Lyophilized PowderPeso molecular:28 KDa (reducing condition)Complement C2 Protein, Mouse, Recombinant (His)
<p>Complement C2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:84.2 kDa (predicted); 91.2 kDa (reducing conditions)Complement C6 Protein, Human, Recombinant (His)
<p>Complement C6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:104 kDa (predicted); 110 kDa (reducing conditions)Complement factor D-IN-1
CAS:<p>Complement factor D-IN-1, a selective small-molecule inhibitor with IC50s of 0.006 μM (Thioesterolytic) and 0.05 μM (MAC Assay).</p>Fórmula:C21H19BrN6O3Cor e Forma:SolidPeso molecular:483.32Complement C5 Protein, Human, Recombinant (Flag)
<p>Complement C5 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with Flag tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:187.36 kDa (predicted); 176.6 kDa, 100.87 kDa and 72.07 kDa (reducing conditions)(Z)-Leukadherin-1
CAS:<p>(Z)-Leukadherin-1 (ADH-503 free base) is an allosteric agonist of CD11b.</p>Fórmula:C22H15NO4S2Pureza:99.23%Cor e Forma:SolidPeso molecular:421.49Complement C2 Protein, Human, Recombinant (His)
<p>Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:98.6%Cor e Forma:Lyophilized PowderPeso molecular:82.5 kDa (predicted)MASP2 Protein, Mouse, Recombinant (His)
<p>MASP2 Protein, Mouse, Recombinant (His) is expressed in E.</p>Cor e Forma:Lyophilized PowderPeso molecular:46.6 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18-20 kDa&27-30 kDa based on Tris-Bis PAGE result.C1s Protein, Human, Recombinant (His)
<p>Complement is an integral component of the adaptive and innate immune systems and represents one of the major effector systems for the immune responses.</p>Cor e Forma:Lyophilized PowderPeso molecular:76.3 kDa (predicted); 82.06 kDa, 56.59 kDa and 33.36 kDa (reducing condition, due to glycosylation)Complement C8 γ Protein, Human, Recombinant (His)
<p>Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G.</p>Cor e Forma:Lyophilized PowderPeso molecular:22 KDa (reducing condition)MASP2 Protein, Rat, Recombinant (E. coli, His)
<p>MASP2 Protein, Rat, Recombinant (E.</p>Cor e Forma:Lyophilized PowderPeso molecular:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.MBL2 Protein, Human, Recombinant (His)
<p>Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins.</p>Pureza:> 99.9% - > 99.9%Cor e Forma:Lyophilized PowderPeso molecular:31 KDa (reducing condition)Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
<p>Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.</p>Cor e Forma:Lyophilized PowderPeso molecular:25.7 kDa (predicted). Due to glycosylation, the protein migrates to 26-30 kDa based on Tris-Bis PAGE result.C1QB Protein, Human, Recombinant (His)
<p>Complement Component 1, q subcomponent (C1q) associates with C1r and C1s in order to yield the first component of the serum complement system.</p>Cor e Forma:Lyophilized PowderPeso molecular:25.2 kDa (predicted); 30 kDa (reducing condition, due to glycosylation)MASP2 Protein, Human, Recombinant (His)
<p>The pathogenesis of severe acute respiratory disease syndrome (SARS) is not fully understood.</p>Cor e Forma:Lyophilized PowderPeso molecular:46.9 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 18 kDa&25-30 kDa based on Tris-Bis PAGE result.C1QBP Protein, Mouse, Recombinant (His)
<p>C1QBP Protein, Mouse, Recombinant (His) is expressed in E.</p>Cor e Forma:Lyophilized PowderPeso molecular:24.7 kDa (predicted); 32 kDa (reducing conditions)Complement C5a Protein, Mouse, Recombinant, Biotinylated
<p>Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E.</p>Cor e Forma:Lyophilized PowderPeso molecular:9 kDa (predicted)Complement C3 Protein, Mouse, Recombinant (aa 25-1663, His)
<p>Expression system: HEK293 Cells<br>Length: 25-1663, Full Length of Mature Protein<br>Activity: Not Tested</p>Cor e Forma:Lyophilized PowderPeso molecular:187.86 kDa (Predicted); 65-68 kDa, 110-115 kDa and 165-180 kDa (Due to glycosylation)Complement C7 Protein, Human, Recombinant (His)
<p>Complement C7 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:92.6 kDa (predicted); 92-98 kDa (reducing conditions)Complement factor I Protein, Human, Recombinant (His)
<p>Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for</p>Cor e Forma:Lyophilized PowderPeso molecular:64.58 kDa (predicted). Due to enzyme lysis and glycosylation, the protein migrates to 75-95 kDa based on Tris-Bis PAGE result.Complement Factor MASP3 Protein, Human, Recombinant (His)
<p>MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway.</p>Cor e Forma:Lyophilized PowderPeso molecular:95-120 KDa (reducing condition)MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated
<p>MASP2 Protein (Primary Amine Labeling), Rat, Recombinant (His), Biotinylated is expressed in E.</p>Cor e Forma:Lyophilized PowderPeso molecular:46.7 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 15-20 kDa&25-30 kDa based on Tris-Bis PAGE result.CFI Protein, Mouse, Recombinant (His)
<p>CFI Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:66.75 kDa (predicted); 126.1 kDa, 59.3 kDa and 46.7 kDa (reducing conditions)MBL1 Protein, Rat, Recombinant (hFc)
<p>MBL1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:50.5 kDa (predicted); 56 kDa (reducing conditions)MASP2 Protein, Cynomolgus, Recombinant (His)
<p>MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E.</p>Cor e Forma:Lyophilized PowderPeso molecular:46.8 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 21-24 kDa&28-30 kDa based on Tris-Bis PAGE result.C1QTNF1 Protein, Human, Recombinant (His)
<p>C1QTNF1 is a secreted protein，contains 1 C1q domain and 1 collagen-like domain.</p>Cor e Forma:Lyophilized PowderPeso molecular:37 KDa (reducing condition)C1s-A subcomponent Protein, Mouse, Recombinant (His)
<p>C1s-A subcomponent Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:76.6 kDa (predicted)Complement C3a Protein, Mouse, Recombinant
<p>Complement C3a Protein, Mouse, Recombinant is expressed in E.</p>Pureza:Greater than 95% as determined by reducing SDS-PAGE - Greater than 95% as determined by reducing SDS-PAGE. (QC verified)Cor e Forma:Lyophilized PowderPeso molecular:9 KDa (reducing condition)Complement C3 Protein, Human, Recombinant (His)
<p>Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:SDS-PAGE: 93.4%; SEC-HPLC: 94.7% - SDS-PAGE: 95.5%; SEC-HPLC: 92.6%Cor e Forma:Lyophilized PowderPeso molecular:186.43 kDa (predicted)Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
<p>Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.</p>Cor e Forma:Lyophilized PowderPeso molecular:52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.Complement Factor D/CFD Protein, Human, Recombinant (hFc)
<p>Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages.</p>Cor e Forma:Lyophilized PowderPeso molecular:51.2 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.Complement C5 Protein, Human, Recombinant (His & FLAG)
<p>Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag.</p>Pureza:96.1%Cor e Forma:Lyophilized PowderPeso molecular:188.8 kDa (predicted)Complement C3 Protein, Cynomolgus, Recombinant (His)
<p>Complement C3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Pureza:90.3%Cor e Forma:Lyophilized PowderPeso molecular:186.40 kDa (predicted)Complement C3a Protein, Human, Recombinant
<p>Complement C3a Protein, Human, Recombinant is expressed in E.</p>Pureza:>99.99% - Greater than 95% as determined by reducing SDS-PAGE.Cor e Forma:Lyophilized PowderPeso molecular:13 KDa (reducing condition)Complement C5 Protein, Cynomolgus, Recombinant
<p>Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells.</p>Cor e Forma:Lyophilized PowderPeso molecular:8.41 kDa (predicted); 12.42 kDa (reducing conditions)Complement C2 Protein, Human, Recombinant (hFc)
<p>Complement C2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:110 kDa (predicted); 110-130 kDa (reducing condition, due to glycosylation)Complement C7 Protein, Human, Recombinant (hFc)
<p>Complement C7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:118 kDa (predicted); 118 kDa (reducing conditions)Complement factor I Protein, Mouse, Recombinant (His)
<p>Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for</p>Cor e Forma:Lyophilized PowderPeso molecular:66.39 kDa (predicted). Due to autocatalytic cleavage and glycosylation, the protein migrates to 80-100 kDa on Tris-Bis PAGE result.Complement C5a Protein, Mouse, Recombinant
<p>Complement C5a Protein, Mouse, Recombinant is expressed in E.</p>Pureza:97.4%Cor e Forma:Lyophilized PowderPeso molecular:9 kDa (predicted)Complement C5 Protein, Cynomolgus, Recombinant (His)
<p>Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:188.1 kDa (predicted); 106.3 and 75.8 kDa (reducing conditions)Complement C2 Protein, Cynomolgus, Recombinant (His)
<p>Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC).</p>Cor e Forma:Lyophilized PowderPeso molecular:82.18 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.Complement C3 Protein, Mouse, Recombinant (aa 994-1310, His)
<p>Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.</p>Cor e Forma:Lyophilized PowderPeso molecular:36.34 kDa (predicted); 32.39 kDa (reducing conditions)C1QBP Protein, Human, Recombinant (His)
<p>C1QBP Protein, Human, Recombinant (His) is expressed in E.</p>Cor e Forma:Lyophilized PowderPeso molecular:24.8 kDa (predicted); 36 kDa (reducing conditions)Compstatin control peptide acetate
CAS:<p>Compstatin control peptide acetate is an inhibitor of complement protein C3 by binding and inhibiting the cleavage of complement C3.</p>Fórmula:C66H101N23O17Pureza:99.02%Cor e Forma:Odour SolidPeso molecular:1488.65BCX 1470 methanesulfonate
CAS:<p>BCX 1470 inhibits factor D & C1s better than trypsin (IC50: 96 nM & 1.6 nM, 3.4- & 200-fold).</p>Fórmula:C15H14N2O5S3Cor e Forma:SolidPeso molecular:398.48PMX 53 acetate(219639-75-5 free base)
CAS:<p>PMX-53 is a potent and orally active CD88 (C5aR) antagonist (IC50: 20 nM) and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50</p>Fórmula:C49H69N11O9Pureza:99.91%Cor e Forma:SolidPeso molecular:956.16Eculizumab
CAS:<p>Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5</p>Pureza:98.20%Cor e Forma:LiquidPeso molecular:148 kDaADH-503
CAS:<p>ADH-503 (GB1275) is an orally available, allosteric CD11b small molecule agonist.Cost-effective and quality-assured.</p>Fórmula:C27H28N2O5S2Pureza:97.03% - >99.99%Cor e Forma:SolidPeso molecular:524.7Danicopan
CAS:<p>Danicopan (ACH-4471), an oral factor D inhibitor, binds strongly (Kd 0.54 nM) and may treat PNH and aHUS.</p>Fórmula:C26H23BrFN7O3Pureza:99.94%Cor e Forma:SolidPeso molecular:580.41JR14a
CAS:<p>JR14a (5-(Bis(4-chlorophenyl)methyl)-3-methylthiophene-2-carbonyl)-l-arginine hydrochloride) is a potent antagonist of human complement C3a receptor.</p>Fórmula:C25H26Cl2N4O3SPureza:99.76%Cor e Forma:SolidPeso molecular:533.47Compstatin
CAS:<p>Compstatin, a cyclic tridecapeptide, which was originally discovered from phage-display libraries, is a highly potent and selective C3 inhibitor.</p>Fórmula:C66H99N23O17S2Pureza:>99.99%Cor e Forma:SolidPeso molecular:1550.77Iptacopan hydrochloride
CAS:<p>Iptacopan hydrochloride (LNP023 hydrochloride) is an orally bioavailable, highly potent and highly selective factor B inhibitor with an IC50 of 10 nM.</p>Fórmula:C25H31ClN2O4Pureza:98.89% - 99.89%Cor e Forma:SolidPeso molecular:458.98Avacopan
CAS:<p>Avacopan (CCX168) is a C5aR antagonist with selective and oral activity. Avacopan can be used to treat ANCA-related vasculitis. Cost-effective and quality-assured.</p>Fórmula:C33H35F4N3O2Pureza:99.47% - 99.9%Cor e Forma:SolidPeso molecular:581.64Leukadherin-1
CAS:<p>Leukadherin-1 boosts CD11b/CD18 adhesion, lowers leukocyte movement, cuts inflammation.</p>Fórmula:C22H15NO4S2Pureza:98.49% - 98.93%Cor e Forma:SolidPeso molecular:421.49
