Antibióticos Naturais e Semissintéticos
Os antibióticos naturais e semissintéticos são caracterizados por estruturas químicas com anéis heterocíclicos e grupos funcionais ativos que inibem o crescimento de microrganismos. Suas estruturas permitem-lhes interagir com os processos vitais das bactérias, tornando-os úteis para o tratamento de infecções bacterianas. Os antibióticos semissintéticos podem ser modificados para melhorar o espectro de atividade ou a resistência à degradação.
Na CymitQuimica, oferecemos antibióticos naturais e semissintéticos de alta qualidade para pesquisa em microbiologia e desenvolvimento farmacêutico.
Foram encontrados 6376 produtos de "Antibióticos Naturais e Semissintéticos"
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Lumefantrine
CAS:<p>Lumefantrine, an antimalarial, treats malaria with artemether, effective against Plasmodium spp. including in chloroquine-resistant areas.</p>Fórmula:C30H32Cl3NOPureza:98.36%Cor e Forma:Yellow SolidPeso molecular:528.94N-Desmethyl Tetracycline-d3 (N-Desmethyl Oxytetracycline EP Impurity B-d3)
Fórmula:C21H19D3N2O8Peso molecular:433.43Tigecycline Metabolite M4 (Epimer of N-Acetyl-9-Aminominocycline)
Fórmula:C25H30N4O8Peso molecular:514.544-AA ((2R,3R)-3-((R)-1-(tert-Butyldimethylsilyloxy)ethyl)-4-oxoazetidin-2-yl acetate)
CAS:Fórmula:C13H25NO4SiPeso molecular:287.43Cefmenoxime Impurity 9 Triethylamine Salt
CAS:Fórmula:C12H12Cl2N6O4S2·C6H15NPeso molecular:439.29 101.19Cefodizime
CAS:<p>Applications Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime maybe useful in the treatment of otitis media, sinusitis and gynaecological infections, and for the prophylaxis or treatment of surgical infections.<br>References Barradel, L.B. et al.: Drugs, 44, 800 (1992); Kasai, K. et al.: Jap. J. Antibiot., 37, 1306 (1984);<br></p>Fórmula:C20H20N6O7S4Cor e Forma:NeatPeso molecular:584.67N-(1-Naphthylmethyl)methylamine Hydrochloride
CAS:Produto Controlado<p>Impurity Terbinafine BP Impurity A; Terbinafine USP Related Compound A<br>Applications N-Methyl-1-naphthalenemethanamine hydrochloride (Terbinafine BP Impurity A; Terbinafine USP Related Compound A) is an intermediate used in the synthesis of various pharmaceuticals such as Terbinafine hydrochloride (T107500) and Butenafine hydrochloride (B690195).<br>References Petranyi, G., et al.: Science, 224, 1239 (1984); Ryder, N.S., et al.: Antimicrob. Agents Chemother., 27, 252 (1985); Evans, E.G.V., et al.: Br. Med. J., 318, 1031 (1999); Kokjohn, K., et al.: Int. J. Dermatol., 42, 11 (2003); Sumikawa, M., et al.: J. Dermatol., 34, 456 (2007)<br></p>Fórmula:C12H13N·ClHCor e Forma:WhitePeso molecular:207.703-(Hydroxymethylene)-6-phenyl-2,5-piperazinedione
CAS:Produto Controlado<p>Applications 3-(Hydroxymethylene)-6-phenyl-2,5-piperazinedione is a derivative of Cephalexin Hydrate (C256800), which is a semi-synthetic cephalosporin antibiotic.<br>References Muggleton, et al.: Antimicrob. Agents Chemother., 253 (1968), Marrelli, L.P., et al.: Anal. Profiles Drug Subs., 4, 21 (1975),<br></p>Fórmula:C11H10N2O3Cor e Forma:NeatPeso molecular:218.209CP 1282 (>85%)
CAS:Produto Controlado<p>Applications CP 1282 is the tautomer of the antibiotic Cefotetan (C242970) with similar degradation rates.<br>References Koshiro, A. et al.: Chem. Pharm. Bull., 37, 1864 (1989); Naber, K. et al.: Zeitsch. Antmickrob. Antineoplast. Chemother., 2, 161 (1984);<br></p>Fórmula:C17H17N7O8S4Pureza:>85%Cor e Forma:NeatPeso molecular:575.62Sisomicin
CAS:Produto Controlado<p>Applications Sisomicin is an Antibacterial. Gentamicin-like aminoglycoside antibiotic; has broad spectrum antibiotic activity.<br>References Weinstein, M.J., et al.: J. Antibiot., 23, 551 (1970), Sculier, J.P., et al.: J. Antimicrob. Chemother., 9, 63 (1982), Noone, P., et al.: Drugs, 27, 548 (1984),<br></p>Fórmula:C19H37N5O7Cor e Forma:NeatPeso molecular:447.53N-Formyl-3-mercaptovaline
CAS:<p>Stability Air Sensitive<br>Applications N-Formyl-3-mercaptovaline acts as a reagent in the preparation of derivatives of D-penicillamine as potential antiarthritic agents.<br>References Reich, M. F., et al.: Bioorg. Med. Chem. Lett., 4, 1167 (1994)<br></p>Fórmula:C6H11NO3SCor e Forma:White To Off-WhitePeso molecular:177.22Decarboxy Gatifloxacin Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Gatifloxacin impurity.<br>References Naber, C., et al.: Antimicrob. Agents Chemother., 45, 293 (2001), Herzler, M., et al.: J. Anal. Toxicol., 27, 233 (2003), Li, Y., et al.: J. Pharm. Biomed. Anal., 35, 1101 (2004),<br></p>Fórmula:C18H22FN3O2•2HClCor e Forma:NeatPeso molecular:331.39 + 2(36.46)Descladinose 6-N-Desmethyl Azithromycin
CAS:<p>Stability Hygroscopic<br>Applications Descladinose 6-N-Desmethyl Azithromycin is a metabolite of Azithromycin (A927018), which is an azalide macrolide antibiotic.<br>References Hunter, R., et al.: J. Vet. Pharmacol. Ther., 26, 117 (2003);<br></p>Fórmula:C29H56N2O9Cor e Forma:WhitePeso molecular:576.7612-Deoxy Roxithromycin
CAS:Produto ControladoFórmula:C41H76N2O14Cor e Forma:NeatPeso molecular:821.05N’-Desmethyl Azithromycin
CAS:<p>Impurity Azithromycin EP Impurity I<br>Stability Hygroscopic<br>Applications N’-Desmethyl Azithromycin (Azithromycin EP Impurity I) is a metabolite of Azithromycin (A927000) as potential anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agent.<br>References Bright, G., et al.: J. Antibiot., 41, 1029 (1988), Goldman, R., et al.: Antimicrob. Agents Chemother., 34, 426 (1990), Gandhi, R., et al.: J. Pharm. Biomed. Anal., 23, 1073 (2000),<br></p>Fórmula:C37H70N2O12Cor e Forma:White To Off-WhitePeso molecular:734.96L-Penicillamine
CAS:Produto Controlado<p>Applications L-Penicillamine is a metabolite of penicillin. L-Penicillamine is used in the treatment of Wilson’s disease, Cystinuria, Scleroderma and arsenic poisoning.<br>References Marti-Prats, L., et al.: Neurosci. Lett., 483, 143 (2010), Singh, A., et al.: J. Pharm. Sci., 99, 3931 (2010), Everette, J., et al.: J. Agric. Food Chem., 58, 8139 (2010),<br></p>Fórmula:C5H11NO2SCor e Forma:White SolidPeso molecular:149.2113Florfenicol
CAS:<p>Applications Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.<br>References Kim, E and Aoki, T.: Microbiol. Immunol., 40, 665, (1996), Keyes, K.: Antimicrob. Agents Chemother., 44, 421 (2000)<br></p>Fórmula:C12H14Cl2FNO4SCor e Forma:YellowPeso molecular:358.21Natamycin
CAS:<p>Stability Hygroscopic, Light Sensitive<br>Applications Polyene antifungal antibiotic.<br>References Levinskas, G.J., et al.: Toxicol. Appl. Pharmacol., 8, 97 (1966), Pandey, R.C., et al.: J. Antibiot., 29, 1035 (1976), Brik, H., et al.: Anal. Profiles Drug Subs. Excip., 23, 399 (1994),<br></p>Fórmula:C33H47NO13Cor e Forma:White To Light BeigePeso molecular:665.73Ceftazidime Pentahydrate(Contain 1 equivalent of Na2CO3 as stabilizer)
CAS:<p>Applications Third generation cephalosporin antibiotic. Antibacterial.<br>References Brodie, A., et al.: Antimicrob. Agents Chemother., 17, 876 (1980), Richards, D.M., et al.: Drugs, 29, 105 (1985), Abounassif, M.A., et al.: Anal. Profiles Drug Subs., 19, 95 (1990),<br></p>Fórmula:C22H22N6O7S2·5H2OCor e Forma:WhitePeso molecular:636.65(5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-[[(methylsulfonyl)oxy]methyl]-2-oxazolidinone
CAS:Produto Controlado<p>Impurity Linezolid USP Related Compound D<br>Applications (5R)-3-[3-Fluoro-4-(4-morpholinyl)phenyl]-5-[[(methylsulfonyl)oxy]methyl]-2-oxazolidinone (Linezolid USP Related Compound D) is an intermediate in the synthesis of Linezolid Dimer (L466520), an impurity of the antibacterial agent Linezolid (L466500).<br>References Xu, Heteroatom, Chem., 19, 316 (2008); Wang, J.W., et al.: Lett. Org. Chem., 5, 336 (2008);<br></p>Fórmula:C15H19FN2O6SCor e Forma:NeatPeso molecular:374.382H,5H-Pyrano[4,3-b]pyranyl Mupirocin Sodium Impurity
CAS:Produto Controlado<p>Impurity Mupirocin EP Impurity E<br>Stability Hygroscopic<br>Applications Mupirocin (M794000) impurity. The rearrangement isomer of Mupirocin is prepared using an enzyme-catalyzed, selective deesterification.<br>References Sime, J.T., et al.: Tetrahedron Lett., 28, 5169 (1987),<br></p>Fórmula:C26H43O9·NaCor e Forma:Off WhitePeso molecular:522.60N-Phenylacetylglycine
CAS:Produto Controlado<p>Applications A metabolite of carboxylic acid.<br>References Bardsley, W., et al.: Biochem. J., 122, 557 (1971), Kim, J., et al.: Biosci. Biotechnol. Biochem., 69, 1331 (2005), Kopka, J., et al.: J. Biotechnol., 124, 312 (2006),<br></p>Fórmula:C10H11NO3Cor e Forma:NeatPeso molecular:193.20Ledipasvir
CAS:Ledipasvir (GS-5885) is a Hepatitis C Virus NS5A Inhibitor.Fórmula:C49H54F2N8O6Pureza:99.96%Cor e Forma:SolidPeso molecular:8893-Formyl Rifamycin
CAS:<p>Applications A metabolite of Rifampicin, a Rifamycin antibiotic.<br>References Assandri, A., et al.: J. Antibiot., 37, 1066 (1984), Utkin, I., et al.: Drug. Metab. Dispos., 25, 963 (1997), Weber, A., et al.: Biopharm. Drug. Dispos., 22(4), 157 (2001), Marek, C., et al.: Biochem. J., 387, 601 (2005),<br></p>Fórmula:C38H47NO13Cor e Forma:Dark RedPeso molecular:725.78Amoxicillin
CAS:<p>Applications Amoxicillin is an antibiotic used in the treatment of various bacterial infections.<br></p>Fórmula:C16H19N3O5SPureza:>90%Cor e Forma:NeatPeso molecular:365.40Retapamulin
CAS:Produto Controlado<p>Applications Retapamulin is an antibacterial agent used as a substitute for the more commonly known Penicillin (P223505).<br>References Goldenthal, E.I., et al.: Toxicol. Appl. Pharmacol., 18, 185 (1971), Dunham, J.M., et al.: Anal. Profiles Drug Subs., 1, 249 (1972),<br></p>Fórmula:C30H47NO4SCor e Forma:NeatPeso molecular:517.76Rifampicin-D3
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Semisynthetic antibiotic. Antibacerial (tuberculostatic).<br>References Furesz, et al.: Antibiot. Chemother., 16, 316 (1970), Gallo, G.G., et al.: Anal. Profiles Drug Subs., 5, 467 (1976),<br></p>Fórmula:C43H55D3N4O12Cor e Forma:RedPeso molecular:825.96Clarithromycin E-9-Oxime
CAS:<p>Impurity Clarithromycin EP Impurity C<br>Applications Clarithromycin 9-Oxime (Clarithromycin EP Impurity C) is an impurity of Clarithromycin (C559750), a macrolide antibiotic.<br>References Stephanic, V. et al.: J. Med. Chem., 54, 719 (2011); Chen, X. et al.: Zhong. Yao., 17, 32 (2008);<br></p>Fórmula:C38H70N2O13Cor e Forma:White To Off-WhitePeso molecular:762.97Fumagillin
CAS:<p>Stability Light Sensitive<br>Applications Fumagillin is a compound isolated from the fungus Aspergillus fumigatus. Fumagillin is an antimicrobial agent used in the treatment of microsporidiosis. Fumagillin shows promise as both an an anti-infective and antiangiogenic agent.<br>References Molina, J.M. et al.: N. Eng. J. Med., 346, 1963 (2002); Hou, L. et al.: Pathol. Int., 59, 448 (2009); Ingber, D. et al.: Nature, 348, 555 (1990);<br></p>Fórmula:C26H34O7Cor e Forma:NeatPeso molecular:458.54Monodecarboxy Piperacilloic Acid (Mixture of Diastereomers)
CAS:Produto Controlado<p>Impurity Piperacillin EP Impurity C<br>Stability Hygroscopic<br>Applications Monodecarboxy Piperacilloic Acid (Piperacillin EP Impurity C) is an impurity of Piperacillin (P479950), a β-lactam antibiotic.<br>References Saikawa, I. et al.: Yakug. Zas., 97, 995 (1977); Saikawa, I. et al.: Yakug. Zas., 97, 1071 (1977); Takano, S. et al.: Yakug. Zas., 97, 1064 (1977);<br></p>Fórmula:C22H29N5O6SCor e Forma:Off White SolidPeso molecular:491.561Aztreonam-d6
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Isotope labelled Aztreonam (A965200), the first totally synthetic monocyclic β-lactam antibiotic.<br>References Sykes, R.B., et al.: Antimicrob. Agents Chemother., 21, 85 (1982), Florey, K., et al.: Anal. Profiles Drug Subs., 17, 1 (1988),<br></p>Fórmula:C13H11D6N5O8S2Cor e Forma:NeatPeso molecular:441.47(19E/Z)-seco Rapamycin Sodium Salt (>80%)
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications A decomposition product of Rapamycin (R124000).<br>References Yatscoff, R.W., et all.: Ther. Drug Monit., 17, 666 (1995), Wacher, V.J., et al.: J. Pharm. Sci., 87, 1322 (1998),<br></p>Fórmula:C51H78NNaO13Pureza:>80%Cor e Forma:NeatPeso molecular:936.154
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