Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one (Ondansetron Impurity G)
CAS:Produto Controlado<p>Applications 1,2,3,9-Tetrahydro-3-(1H-imidazol-1-ylmethyl)-9-methyl-4H-carbazol-4-one is an metabolite of Ondansetron (O655000), is a selective 5-hydroxytryptamine3 (5-HT3) receptor antagonist that has been introduced to clinical practice as an antiemetic for cancer treatment-induced and anesthesia-related nausea and vomiting.<br>References Kris, M.G., et al.: J. Clin. Oncol., 6, 659 (1988), Faris, P..L., et al.: Lances, 355, 792 (2000), Ye, J.H., et al.: CNS Drug Reviews., 7, 199 (2001);<br></p>Fórmula:C17H17N3OCor e Forma:White To Off-WhitePeso molecular:279.34Nimodipine
CAS:<p>Applications A dihydropyridine calcium channel blocker. It is used as a vasodilator (cerebral). Neuroprotective & Neuroresearch products.<br>References Allen, G.S., et al.: N. Engl. J. Med., 308, 619 (1983), Schluter, H.: Arzneim.-Forsch., 36, 1733 (1986), Deyo, R.A., et al.: Science, 243, 809 (1989),<br></p>Fórmula:C21H26N2O7Cor e Forma:NeatPeso molecular:418.44Ref: 10-F505379
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarPyrazinecarboxylic Acid-d3
CAS:Produto Controlado<p>Applications Labelled analogue of Pyrazinecarboxylic Acid, a very potent urate retaining drug. Pyrazinecarboxylic Acid is a metabolite of the antibacterial agent Pyrazinamide (P840600).<br>References Fanelli, G.M. et al.: J. Clin. Invest., 52, 1946 (1973): Fanelli, G.M. et al.: J. Pharmacol. Exp. Therap., 200, 413 (1977); Lacroix, C. et al.: Arzneim.-Forsch., 40, 76 (1990); Kraemer, H.-J. et al.: J. Chrom. B Niomed. Sci. Appl., 706, 319 (1998);<br></p>Fórmula:C5HD3N2O2Cor e Forma:White To Light YellowPeso molecular:127.124-Chlorobenzamide
CAS:Produto Controlado<p>Applications 4-chlorobenzamide (cas# 619-56-7) is a useful research chemical.<br></p>Fórmula:C7H6ClNOCor e Forma:NeatPeso molecular:155.58Benzhydrol
CAS:<p>Impurity Diphenhydramine EP Impurity D<br>Applications Intermediate in the preparation of Modafinil (M482500).<br>References Kumar, C., et al.: Eur. J. Med. Chem., 44, 1223 (2009),<br></p>Fórmula:C13H12OCor e Forma:WhitePeso molecular:184.233-(2-Methylpyridin-4-yl)-1-trityl-1H-pyrazolo[4,3-c]pyridin-6-amine
CAS:Pureza:95%Peso molecular:467.57598876953125Propylthiouracil
CAS:Produto Controlado<p>Applications Antihyperthyroid. Has been used to promote fattening. This substance is reasonably anticipated to be a human carcinogen.<br>References Aboul-Enein, H.Y., et al.: Anal. Profiles Drug Subs., 6, 457 (1977), Cooper, D.S., et al.: N. Engl. J. Med., 311, 1353 (1984),<br></p>Fórmula:C7H10N2OSCor e Forma:White To Off-WhitePeso molecular:170.23N-Citryl (R)-Phenylephrine (Mixture of Diastereomers)
Produto Controlado<p>Applications N-Citryl (R)-Phenylephrine is a derivative of (R)-Phenylephrine (P320640), an α-Adrenergic agonist. Mydriatic; decongestant.<br>References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 86, 284 (1946), Gaglia, C.A., et al.: Anal. Profiles Drug Subs., 3, 483 (1974)<br></p>Fórmula:C15H19NO8Cor e Forma:White To Light YellowPeso molecular:341.31O-Desmethyl Mebeverine Acid
CAS:Produto ControladoFórmula:C15H23NO3Cor e Forma:NeatPeso molecular:265.354-ethoxy-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:285.36999511718756-nitro-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:286.30999755859375trans-Haloperidol N-Oxide
CAS:Produto Controlado<p>Applications trans-Haloperidol N-Oxide is the trans-isomer of Haloperidol N-Oxide (H103735), a metabolite of Haloperidol (H103700).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gorrod, J., et al.: Xenobiotica., 23, 495 (1993); Monser, L., et al.: J. Liquid. Chromatograph. Technol., 26, 261 (2003);<br></p>Fórmula:C21H23ClFNO3Cor e Forma:NeatPeso molecular:391.861-[(1-Oxopentyl)amino]-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-cyclopentanecarboxamide
CAS:Produto Controlado<p>Impurity Irbesartan EP Impurity A; Irbesartan USP Related Compound A; Irbesartan Metabolite<br>Applications 1-[(1-Oxopentyl)amino]-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-cyclopentanecarboxamide (Irbesartan EP Impurity A; Irbesartan USP Related Compound A; Irbesartan Metabolite) is a metabolite of Irbesartan (I751000), an angiotensin II type 1 (AII1)-receptor antagonist.<br>References Alexandre, V., et. al.: J. Mol. Catal. B-Enzym., 29, 173 (2004); Rao, D.D., et. al.: J. Liq. Chromatogr. R. T., 35, 1973 (2012)<br></p>Fórmula:C25H30N6O2Cor e Forma:NeatPeso molecular:446.543-Chloro-4-morpholino-1,2,5-thiadiazole
CAS:Produto Controlado<p>Impurity Timolol EP Impurity F; Timolol BP Impurity F; Timolol USP Related Compound F<br>Applications 3-Chloro-4-morpholino-1,2,5-thiadiazole (Timolol EP Impurity F; Timolol BP Impurity F; Timolol USP Related Compound F) is an intermediate for the synthesis of Timolol.<br>References Wasson, B., et al.: J. Med. Chem., 15, 651 (1972), Tokunaga, M., et al.: Sci., 277, 936 (1997),<br></p>Fórmula:C6H8ClN3OSCor e Forma:White To Off-WhitePeso molecular:205.67Norfloxacin-d5
CAS:Produto Controlado<p>Applications Norfloxacin-d5 is deuterium labeled Norfloxacin (N681000), a synthetic fluoroquinolone and an antibacterial agent. Norfloxacin can be used to treat urinary tract infections.<br>References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),<br></p>Fórmula:C162H5H13FN3O3Cor e Forma:NeatPeso molecular:324.36Prochlorperazine
CAS:Produto Controlado<p>Applications Prochlorperazine is antiemetic, antipsychotic; used in treatment of vertigo.<br>References Taylor, W.B., et al.: Br. J. Clin. Pharmacol., 23, 137 (1987), Ward, A.E., Br. J. Clin. Pract., 42, 228 (1988),<br></p>Fórmula:C20H24ClN3SCor e Forma:YellowPeso molecular:373.94(R)-2-Bromo Phenylephrine Hydrochloride
CAS:Produto Controlado<p>Applications (R)-2-Bromophenylephrine is the R-2-brominated analogue of the α-adrenergic agonist, Phenylephrine (P320640).<br></p>Fórmula:C9H13BrClNO2Cor e Forma:NeatPeso molecular:282.56N-Des-(2-chloroethyl) Chlorambucil
CAS:Produto Controlado<p>Applications N-Des-(2-chloroethyl) Chlorambucil is the half-mustard analog of Chlorambucil (C325050) and exhibits mutagenic activity.<br>References Ferguson, L.R., et al.: Anti-Cancer Drug Des., 3, 67 (1988)<br></p>Fórmula:C12H16ClNO2Cor e Forma:Off WhitePeso molecular:241.714Dehydro Nifedipine
CAS:Produto Controlado<p>Impurity Nifedipine EP Impurity A<br>Applications The main Nifedipine metabolite in human plasma.This compound is a contaminant of emerging concern (CECs).<br>References Guengerich, F., et al.: J. Biol. Chem., 261, 5051 (1986), Bork, R., et al.: J. Biol. Chem., 264, 910 (1989), Kerla, V., et al.: Biochem. Pharmacol., 44, 1745 (1992),<br></p>Fórmula:C17H16N2O6Cor e Forma:Light YellowPeso molecular:344.32Iloperidone
CAS:Produto Controlado<p>Applications Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995), Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995), Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996),<br></p>Fórmula:C24H27FN2O4Cor e Forma:White To Off-WhitePeso molecular:426.481-Methyl-4-[5-(2-methylsulfamoylethyl)-1H-indol-3-yl]pyridinium Chloride
Produto Controlado<p>Impurity Naratriptan pyridinium Impurity<br>Stability Hygroscopic<br>Applications Naratriptan (N378730) impurity.<br></p>Fórmula:C17H20ClN3O2SCor e Forma:NeatPeso molecular:365.88N-Chloro Ethyl ThioTEPA
CAS:Produto Controlado<p>Stability Hygroscopic, Moisture Sensitive<br>Applications N-Chloro Ethyl ThioTEPA is an impurity of ThioTEPA which is an alkylating agent used to treat cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Maanen, M., et al.: Cancer Treatment Rev., 26, 257 (2000); Sykes, M., et al.: Cancer, 6, 142 (1953)<br></p>Fórmula:C6H13ClN3PSCor e Forma:White To Off-WhitePeso molecular:225.684-AMINO-1-[2,3-O-(1-METHYLETHYLIDENE)PENTOFURANOSYL]-1,3,5-TRIAZIN-2(1H)-ONE
CAS:Pureza:95.0%Peso molecular:284.27200317382814-ethyl-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.36999511718752-(4-methylpyridin-2-yl)-1,3-dioxoisoindoline-5-carboxylic acid
CAS:Pureza:95.0%Peso molecular:282.2550048828125Felodipine Ester Lactone
CAS:Produto Controlado<p>Applications Felodipine Ester Lactone is an intemediate used in the synthesis of Dehydro Felodipine Ester Lactone (D229690), which is a metabolite of Felodipine (F232375).<br>References Wang, S.X. et al.: J. Pharmacol. Exp. Therap., 250, 632 (1989); Baeaernhielm, C. et al.: Drug Metab. Disp., 14, 613 (1986);<br></p>Fórmula:C17H15Cl2NO4Cor e Forma:NeatPeso molecular:368.212,6-Dimethoxypyridine-3,5-diamine hydrochloride
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:205.63999938964844Diclazuril 6-Carboxamide
CAS:Produto Controlado<p>Applications Diclazuril 6-Carboxamide is an impurity of Diclazuril (D436200), a nucleotide analog with broad-spectrum anticoccidial activity.<br></p>Fórmula:C18H10Cl3N5O3Cor e Forma:NeatPeso molecular:450.6622-Hydroxy Mifepristone-d6
CAS:Produto Controlado<p>Applications A labelled metabolite of Mifepristone.<br>References Heikinheimo, O., et al.: J. Steroid Biochem., 26, 279 (1987), Brogden, R., et al.: Drugs, 45, 384 (1993), Shi, Y., et al.: Contraception, 48, 133 (1993), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C29H29D6NO3Cor e Forma:NeatPeso molecular:451.634-Phenyl-2-(4-pyridyl)thiazole-5-carboxylic acid
CAS:Cor e Forma:SolidPeso molecular:282.32000732421875Cloperastine Fendizoate
CAS:<p>Stability Hygroscopic<br>Applications Cloperastine fendizoate is used in the treatment of chronic non-productive cough. Antitussive. it is the salt of Cloperastine (CAS:3703-76-2)<br>References Aliprandi, P. et al.: Clin. Drug Invest. 22, 209 (2002)<br></p>Fórmula:C20H24ClNO·C20H14O4Cor e Forma:White To Off-WhitePeso molecular:648.19METHYL 1-CHLORO-4-HYDROXY-7-PHENOXYISOQUINOLINE-3-CARBOXYLATE
CAS:Pureza:90.0%Peso molecular:329.739990234375Hydroxy Brimonidine Trifluoroacetic Acid Salt
CAS:<p>Impurity Brimonidine EP Impurity G<br>Applications A possible metabolite of Brimonidine (B677520).<br></p>Fórmula:C11H12BrN5O·C2HF3O2Cor e Forma:NeatPeso molecular:424.1732Vadadustat
CAS:<p>Applications Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.<br>References Pergola, P., et al.: Kidney Int., 90, 1115 (2016);<br></p>Fórmula:C14H11ClN2O4Cor e Forma:BeigePeso molecular:306.70Didesmethyl Cariprazine
CAS:Produto Controlado<p>Applications Didesmethyl Cariprazine, s a derivative of Cariprazine (C183490) which is an orally active D2/D3 dopamine receptor antagonist (1,2,3). Cariprazine is an antipsychotic drug candidate for the potential treatment of schizophrenia, bipolar mania and depression.<br>References Gruender, G.: Curr. Opin. Invest. Drugs, 11, 823 (2010); Seneca, N. et al.: Psychopharmacology, 218, 579 (2011); Kiss, B. et al.: J. Pharmacol. Exp. Therap., 333, 328 (2010)<br></p>Fórmula:C19H28Cl2N4OCor e Forma:NeatPeso molecular:399.36Ref: 10-F014390
1g247,00€5g624,00€10gA consultar2.5g375,00€50mg67,00€100mg97,00€250mg128,00€500mg194,00€1-(4-Methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:309.32101440429694-(4-Methylpiperazinomethyl)benzoic Acid, Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-(4-Methylpiperazinomethyl)benzoic Acid, Dihydrochloride (cas# 106261-49-8) is a compound useful in organic synthesis.<br></p>Fórmula:C13H18N2O2·2ClHCor e Forma:NeatPeso molecular:307.222,3-Dihydroxypropyl 2-((7-chloroquinolin-4-yl)amino)benzoate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:372.809997558593752-[(1S,3R)-3-Hydroxycyclopentyl]-9-methoxy-1,8-dioxo-N-[(2,4,6-trifluorophenyl)methyl]pyrido[1,2-a]pyrazine-7-carboxamide
CAS:Fórmula:C22H20F3N3O5Cor e Forma:Neat7-Hydroxy Quetiapine-d8
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.<br>References Newton, D., et al.: Drug Metab. Dispos., 23, 154 (1995), Tanaka, E., et al.: J. Clin. Pharm. Ther., 24, 7 (1999)<br></p>Fórmula:C21H17D8N3O3SCor e Forma:NeatPeso molecular:407.562-([1,1'-Biphenyl]-4-yl)-6-fluoroquinoline-4-carboxylic acid
CAS:Pureza:98%Peso molecular:343.356994628906257-Methoxy-1-naphthaleneethanamine Hydrochloride
CAS:Produto ControladoFórmula:C13H15NO·ClHCor e Forma:NeatPeso molecular:237.732-(2-Chlorophenyl)-2-(methylamino)-6-(thiophen-2-ylmethylidene)cyclohexan-1-one
CAS:Pureza:98%Peso molecular:331.86Ref: 10-F614479
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultar(R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS:<p>Applications (R)-3-(4-Phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine is an intermediate used to prepare pyrazolo-pyrimidine compounds as inhibitors of Bruton's tyrosine kinase. It is also an intermediate for Ibrutinib (I124970) derivatives.<br>References Chen, W., et al.: PCT Int. Appl. (2011), WO 2011046964 A2 20110421<br></p>Fórmula:C22H22N6OCor e Forma:White To Light YellowPeso molecular:386.454,5-dimethyl-N-(pyridin-4-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:269.3699951171875Raltitrexed
CAS:Produto Controlado<p>Applications Folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jodrell, D.I., et al.: Cancer Chemother. Pharmacol., 28, 331 (1991), Jackman, A.L., et al.: Eur. J. Cancer, 31A, 1277 (1995)<br></p>Fórmula:C21H22N4O6SCor e Forma:NeatPeso molecular:458.495’-[(Desloratadine)methyl] Rupatadine
CAS:Produto Controlado<p>Applications 5’-[(Desloratidine)methyl] Rupatadine is an impurity of the antihistaminic drug Rupatadine (R701650).<br>References Wang, H. et al.: Yao. Fen. Zaz., 29, 791 (2009);<br></p>Fórmula:C45H43Cl2N5Cor e Forma:NeatPeso molecular:724.76S-Hydroxy Topiramate
CAS:Produto Controlado<p>Applications A metabolite of Topiramate.<br>References Maryanoff, B., et al.: J. Med. Chem., 30, 880 (1987), Shank, R., et al.: Epilepsia, 35, 450 (1994), Streeter, A., et al.: Drug Metab. Disp., 23, 90 (1995),<br></p>Fórmula:C12H21NO9SCor e Forma:Off-White To BeigePeso molecular:355.36Deracoxib
CAS:Produto Controlado<p>Applications Deracoxib is a non-steroidal anti-inflammatory drug (NSAID) of the coxib class. Deracoxin is a selective cyclooxygenase-2 (COX-2) inhibitor used in the treatment of osteoarthritis in dogs. At low doses, adminsitartion of Deracoxin showed no factors associated with gastrointestinal tract perforation.<br>References Lascelles, B.D.X. et al.: J. Am. Vet. Med. Assoc., 227, 1112 (2005); Anderson, G.D. et al.: Inflam. Res., 58, 109 (2009); Brainard, B.M. et al.: Am. J. Vet. Res., 68, 251 (2007);<br></p>Fórmula:C17H14F3N3O3SCor e Forma:Light BrownPeso molecular:397.37trans-Hydroxy Perhexiline (Mixture of Diastereomers)
CAS:Produto ControladoFórmula:C19H35NOCor e Forma:NeatPeso molecular:293.49N-Isopropyl-2-methyl-2-propyl-3-hydroxypropyl Carbamate
CAS:Produto Controlado<p>Applications An intermediate in the synthesis of Carisoprodol.<br></p>Fórmula:C11H23NO3Cor e Forma:NeatPeso molecular:217.31Loxapine-d8 Hydrochloride
CAS:Produto ControladoFórmula:C18H10D8ClN3O·xHClCor e Forma:Off-White To Light YellowPeso molecular:372.324-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide
CAS:<p>Applications 4-[2-[1-(4-Methylphenyl)ethylidene]hydrazinyl]benzenesulfonamide is an impurity of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis. Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.<br>References Simon, L.S., et al.: Arthritis Rheum., 41, 1591 (1998), Silverstein, F.E., et al.: J. Am. Med. Assoc., 284, 1247 (2000), Steinbach, G., et al.: N. Engl. J. Med., 342, 1946 (2000),<br></p>Fórmula:C15H17N3O2SCor e Forma:White To Light YellowPeso molecular:303.384-[2-(2-methoxyethoxy)ethoxy]-6-(pyridin-2-yl)-2,2'-bipyridine
CAS:Pureza:95.0%Peso molecular:351.406005859375Sibutramine, Hydrochloride Monohydrate
CAS:Produto ControladoFórmula:C17H26ClN·ClH·H2OCor e Forma:Off White SolidPeso molecular:334.322-(4-Methanesulfonyl-phenyl)-1-(6-methyl-pyridin-3-yl)-ethanone
CAS:<p>Applications This compound is an impurity in the synthesis of Etoricoxib (E934100), a specific inhibitor of COX-2 .<br>References McGeer, P.L., et al.: Exp. Gerontol., 37, 925 (2002), Chenevard, R., et al.: Circulation, 107, 405 (2003)<br></p>Fórmula:C15H15NO3SCor e Forma:BeigePeso molecular:289.353-Dehydroxy Salbutamol
CAS:Produto Controlado<p>Impurity Levalbuterol USP Related Compound B; Salbutamol EP Impurity C<br>Applications 3-Dehydroxy Salbutamol (Levalbuterol USP Related Compound B; Salbutamol EP Impurity C) is an isoprenaline based selective stimulants of β-adrenergic receptors in bronchial muscles.<br>References Hartley, D., et al.: Nature., 219, 5156 (1968);<br></p>Fórmula:C13H21NO2Cor e Forma:NeatPeso molecular:223.31(4S)-4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic Acid Monomethyl Ester
CAS:Produto ControladoFórmula:C16H15Cl2NO4Cor e Forma:NeatPeso molecular:356.201(R)-2-((4-Aminophenethyl)amino)-1-phenylethanol Hydrochloride
CAS:Produto ControladoFórmula:C16H21ClN2OCor e Forma:NeatPeso molecular:292.8Olanzapine-d3 N-Oxide
CAS:Produto Controlado<p>Applications A labelled metabolite of Olanzapine.<br>References Jacobsen, E., et al.: Acta Pharmacol. Toxacol., 11, 135 (1955), Chakrabarti, J.K., et al.: J. Med. Chem., 23, 878 (1980), Luo, H., et al.: J. Pharm. Sci., 11, 1079 (1992), Moore, N.A., et al.: Curr. Opin. Invest. Drugs, 2, 281 (1993),<br></p>Fórmula:C17H17D3N4OSCor e Forma:NeatPeso molecular:331.45Reboxetine-d5 Mesylate
CAS:Produto ControladoFórmula:C20H22D5NO6SCor e Forma:Off White SolidPeso molecular:414.53N-(2-Benzylphenyl)-2-oxo-1,2-dihydroquinoline-4-carboxamide
CAS:Pureza:98%Peso molecular:354.40899658203125Defluoro Dolutegravir (>85%)
CAS:<p>Applications Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.<br>References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011);<br></p>Fórmula:C20H20FN3O5Pureza:>85%Cor e Forma:NeatPeso molecular:401.39[2-(1H-indol-3-yl)ethyl][(pyridin-4-yl)methyl]amine hydrochloride
CAS:Pureza:95.0%Peso molecular:287.7900085449219O-Desmethyl Everolimus (Technical Grade)
CAS:Produto Controlado<p>Applications O-Desmethyl Everolimus is an impurity of Everolimus (E945400). Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),<br></p>Fórmula:C52H81NO14Cor e Forma:NeatPeso molecular:944.26,7,8,9-Tetrahydro Carvedilol
CAS:Produto Controlado<p>Applications Carvedilol (C184625) derivative.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C24H30N2O4Cor e Forma:NeatPeso molecular:410.511,1-Cyclohexanediacetic Acid Monoamide
CAS:Produto Controlado<p>Applications 1,1-Cyclohexanediacetic acid monoamide is an impurity of Gabapentin (G117250), an amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Gabapentin is used as an anticonvulsant.<br>References Vollmer, K.-O. et al.: Arzneimittel-Forshc., 36, 830 (1986), Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Fórmula:C10H17NO3Cor e Forma:White To Off-WhitePeso molecular:199.2477-(4-Iodobutoxy)-3,4-dihydroquinolin-2-one
CAS:Produto Controlado<p>Impurity Aripiprazole Iodobutoxyquinoline Impurity<br>Applications An impurity in the synthesis of Aripiprazole (A771000). A degradation product in Aripiprazole tablets. Aripiprazole Iodobutoxyquinoline Impurity<br>References Shah, V., et al.: J. Pharm. Sci., et al.: 81, 309 (1992), Zuo, X., et al.: Chromatographia, 64, 387 (2006),<br></p>Fórmula:C13H16INO2Cor e Forma:Off-WhitePeso molecular:345.181,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one
CAS:Produto Controlado<p>Impurity Ondansetron EP Impurity D; Ondansetron USP Related Compound D<br>Applications 1,2,3,9-Tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one (Ondansetron EP Impurity D; Ondansetron USP Related Compound D) is an impurity of Ondansetron (O655000).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, R. et al.: Zhong. Yaox. Zaz., 46, 1436 (2011); Zizkovsky, V. et al.: J. Pharm. Biomed. Anal., 44, 1048 (2007)<br></p>Fórmula:C14H13NOCor e Forma:WhitePeso molecular:211.26
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