Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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N-Desmethyl-N-cyclopentyl Tadalafil
CAS:Produto Controlado<p>Applications N-Desmethyl-N-cyclopentyl Tadalafil is used as a reagent to synthesize tetracyclic cGMP-specific phosphodiesterase inhibitors, compounds that have potential to treat cardiovascular disorders and erectile dysfunction.<br>References Daugan, A. & Gellibert, F. Tetracyclic cGMP-specific Phosphodiesterase Inhibitors and Their Use in Disease Treatment. U.S. 6143746. Nov 7, 2000<br></p>Fórmula:C26H25N3O4Cor e Forma:NeatPeso molecular:443.49Bufuralol Hydrochloride
CAS:Produto Controlado<p>Applications A β-Adrenergic blocker with peripheral vasodilating activity. Antianginal; antihypertensive.<br>References Francis, R.J., et al.: Eur. J. Clin. Pharmacol., 23, 529 (1982), Pfisterer, M., et al.: J. Cardiovasc. Pharmacol., 6, 417 (1984), Narimatsu, S., et al.: J. Pharmacol. Exp. Ther., 303, 172<br></p>Fórmula:C16H23NO2·ClHCor e Forma:White To Light BeigePeso molecular:297.822-Hydroxymethyl Loratadine
CAS:Produto Controlado<p>Impurity Loratadine 2-Hydroxymethyl Impurity (USP)<br>Applications A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor. Loratadine 2-Hydroxymethyl Impurity (USP).<br>References Okamoto, T., et al.: Chem. Pharm. Bull ., 7, 130 (1959), Eyjolfsson, R., et al.: Pharmazie, 58, 154 (2003),<br></p>Fórmula:C23H25ClN2O3Cor e Forma:NeatPeso molecular:412.911-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester (>90%)
<p>Impurity Fesoterodine Impurity 6;<br>Applications 1-[[3-[(1R)-3-[Bis(1-methylethyl)amino]-1-phenylpropyl]4-hydroxyphenyl]methyl 2-Butanedioic Acid Ester is derived from (R)-Fesoterodine Fumarate (F321300), which is a muscarinic receptor antagonist for the treatment of Lower Urininary Tract Symptoms (LUTS). It is very similar to Tolterodine (T535800).<br>References Rogers, D., et al.: Pharmacotherapy, 20, 1092 (2000), Praharaj, S., et al.: J. Psychopharmacology, 19, 426 (2005),<br></p>Fórmula:C26H35NO5Pureza:>90%Cor e Forma:NeatPeso molecular:441.564-Chloro-4'-fluorobutyrophenone
CAS:Produto Controlado<p>Applications 4-Chloro-4'-fluorobutyrophenone (cas# 3874-54-2) is a compound useful in organic synthesis.<br></p>Fórmula:C10H10ClFOCor e Forma:NeatPeso molecular:200.645-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid
CAS:Produto Controlado<p>Applications 5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic Acid is useful for the synthesis of 5-Bromo-7-azaindolin-2-one derivatives which possesses in vitro activity against selected cancer cell lines.<br>References Zhang, J., et al.: Molecules, 21, 1674-1683 (2016);<br></p>Fórmula:C8H9NO3Cor e Forma:NeatPeso molecular:167.16(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol
CAS:<p>Stability Hygroscopic<br>Applications (3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-ol was used to preapare AZD6140 as an orally active reversible P2Y12 receptor antagonist for prevention of thrombosis.<br>References Zhang, H., et al.: Bioorg. Med. Chem. Lett., 22, 3598 (2012);<br></p>Fórmula:C8H15NO3Cor e Forma:NeatPeso molecular:173.213-Hydroxy Imiquimod
CAS:Produto Controlado<p>Applications 4-Amino-β-methyl-1H-imidazo[4,5-c]quinoline-1-propanol, is an aryl ether substituted imidazoquinolines, which can be used in the design of immunomodulating agents for use as vaccine adjuvants and anticancer treatments.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, C., et al.: ACS Med. Chem. Lett., 3, 501 (2012);<br></p>Fórmula:C14H16N4OCor e Forma:NeatPeso molecular:256.3(AlphaR)-α-Methyl-N-[3-(3-methylphenyl)propyl]-1-naphthalenemethanamine Hydrochloride
CAS:Produto Controlado<p>Applications (αR)-α-Methyl-N-[3-(3-methylphenyl)propyl]-1-naphthalenemethanamine, is an impurity of Cinacalcet (C441800), which is a drug that acts as a calcimimetic, and is used to treat secondary hyperparathyroidism (elevated parathyroid hormone levels).<br>References Franceschini N., et al.: Expert Opin. Invest. Drugs, 12, 1413 (2003), Block, G.A., et al.: N. Engl. J. Med. 350, 1516 (2004),<br></p>Fórmula:C22H25NCor e Forma:NeatPeso molecular:303.44Phthalic Hydrazide
CAS:<p>Applications Phthalic Hydrazide is a reagent in the synthesis in various pyrazolophthalazine derivatives.<br>References Rezaei, S.et al.: Tetra. Lett., 53, 5123 (2012);<br></p>Fórmula:C8H6N2O2Cor e Forma:NeatPeso molecular:162.15cis-Tadalafil
CAS:Produto Controlado<p>Impurity Tadalafil EP Impurity A<br>Applications The (6R)-cis-enantiomer of Tadalafil (T004500). Tadalafil Impurity (6R,12aS)<br>References Aldridge, J., et al.: Br. Med. J., 318, 669 (1999), Daugan, A., et al.: J. Med. Chem., 46, 4533 (2003), Vredenbregt, M., et al.: J. Pharm. Biomed. Anal., 40, 840 (2006),<br></p>Fórmula:C22H19N3O4Cor e Forma:Off-WhitePeso molecular:389.404-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2-methoxy-benzamide
CAS:<p>Impurity Amisulpride EP Impurity C<br>Applications 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2-methoxy-benzamide is an impurity of Amisulpride (A633250), an antipsychotic. Amisulpride is a dopamine receptor antagonist. (Amisulpride EP Impurity C). Dopamine imaging agent<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),<br></p>Fórmula:C15H22IN3O2Cor e Forma:NeatPeso molecular:403.263-Hydroxy-4-morpholino-1,2,5-thiazole
CAS:<p>Impurity Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D<br>Applications 3-Hydroxy-4-morpholino-1,2,5-thiazole (Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D) is an intermediate for the preparation of Timolol.<br>References Bodor, N., et al.: J. Med. Chem., 31, 100 (1988),<br></p>Fórmula:C6H9N3O2SCor e Forma:White To Off-WhitePeso molecular:187.22Tulobuterol-d9 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled Tulobuterol (T897250). A sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. A β-adrenergic receptor agonist, related structurally to Terbutaline (T109750).<br>References Kubo, S., et al.: Arzneim.-Forsch., 25, 1028 (1975), Uematsu, T., et al.: Eur. J. Clin. Pharmacol., 44, 361 (1993), Qureshi, S., et al.: J. Exp. Med., 189, 615 (1999),<br></p>Fórmula:C122H9H9ClNO·ClHCor e Forma:White To Off WhitePeso molecular:273.25Hemiacetorphan
CAS:Produto Controlado<p>Applications Hemiacetorphan is an impurity of Racecadotril (R070600), which is antidiarrheal, enkephalinase inhibitor, and also capable of reducing the amount of water and electrolytes into the intestine.<br>References Cezard, J., et al.: Gastroenterol., 120, 799 (2001), Sato, T., et al.: J. Med. Chem., 51, 7705 (2008), Lakshmana, P., et al.: J. Pharm. Res., 8, 39 (2009),<br></p>Fórmula:C14H17NO4SCor e Forma:NeatPeso molecular:295.35Dechloro Trazodone
CAS:Produto Controlado<p>Impurity Trazodone Deschloro Impurity<br>Stability Hygroscopic<br>Applications A Trazodone (T718500) impurity. An antipsychotic with potential use as a schizophrenia agent. Trazodone impurity B.<br>References Pai, N. et al.: J. Chem Pharmaceut. Res., 2, 458 (2010); Silvestrini, B., et al.: Eur. J. Pharmacol., 12, 231 (1970); Brogden, R.N., et al.: Drugs, 21, 401 (1981);<br></p>Fórmula:C19H23N5OCor e Forma:NeatPeso molecular:337.42Amantadine
CAS:Produto Controlado<p>Applications Amantadine is useful in biology studies. Particularly it has been used for solid-state NMR and membrane protein studies.<br>References Shigeta, A., et al.: New Developments in NMR, 20, 457 (2019)<br></p>Fórmula:C10H17NCor e Forma:White To Off-WhitePeso molecular:151.25Depropylamino Chloro Propafenone
CAS:<p>Impurity Propafenone EP Impurity E; Propafenone BP Impurity E; Propafenone USP Impurity E<br>Applications Depropylamino Chloro Propafenone (Propafenone EP Impurity E; Propafenone BP Impurity E; Propafenone USP Impurity E) is an impurity of Propafenone (D288655).<br>References Hollmann, M., et al.: Arzneim.-Forsch., 33, 763 (1983); Bryson, H. M., et al.:Drugs, 45, 85 (1993);<br></p>Fórmula:C18H19ClO3Cor e Forma:NeatPeso molecular:318.79(3S,4S,3’S)-Ezetimibe
CAS:<p>Applications (3S,4S,3’S)-Ezetimbe is a 3-epimer impurity of Ezetimibe (E975000), a cholesterol absorption inhibitor.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Fórmula:C24H21F2NO3Cor e Forma:Off-WhitePeso molecular:409.43Intedanib
CAS:Produto Controlado<p>Applications It is an indolinone derivative potently blocking VEGF-, PDGF-, and FGF-receptor kinases; an indolinone as triple angiokinase inhibitors. An antitumor agent.<br>References Sun, L., et al.: J. Med. Chem., 41, 2588 (1998); Xie, H., et al.: J. Med. Chem., 50, 4898 (2007); Hilberg, F., et al.: Cancer Res., 68, 4774 (2008); Roth, G., et al.: J. Med. Chem., 58, 1053 (2015)<br></p>Fórmula:C31H33N5O4Cor e Forma:NeatPeso molecular:539.62Topiramate Dimer Derivative
Produto Controlado<p>Applications Topiramate Dimer Derivative is an impurity of Topiramate (T540250). Topiramate is an anticonvulsant.<br>References Maryanoff, B.E., et al.: J. Med. Chem., 30, 880 (1987); Bialer, M.: Clin. Pharmacokinet., 24(6), 441-52 (1993)<br></p>Fórmula:C25H40N2O14SCor e Forma:NeatPeso molecular:624.655Meclizine
CAS:Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptorsFórmula:C25H27ClN2Pureza:99.55%Cor e Forma:SolidPeso molecular:390.952-Hydroxy-6-(trifluoromethyl)nicotinamide
CAS:Fórmula:C7H5F3N2O2Pureza:≥97%Cor e Forma:SolidPeso molecular:206.124Propoxyphenyl Thiosildenafil
CAS:Produto Controlado<p>Applications Propoxyphenyl-thiosildenafil is an analogue of Thiosildenafil (T371500). Propoxyphenyl-thiosildenafil has been used in the preparation of novel pyrazolopyrimidinethiones as PDE5 inhibitors for treating erectile dysfunction.<br></p>Fórmula:C23H32N6O3S2Cor e Forma:NeatPeso molecular:504.67(S)-Lisinopril Dimer
CAS:Produto Controlado<p>Applications (S)-Lisinopril (L468985) impurity. Lisinopril Impurity G (Dimer Impurity)<br></p>Fórmula:C42H60N6O9Cor e Forma:WhitePeso molecular:792.96Maraviroc-d6
CAS:Produto Controlado<p>Applications Potent, non-competitive CCR5 receptor antagonist; inhibits binding of HIV viral coat protein gp120. Antiviral.<br>References Fumero, E., et al.: Clin. Microbiol. Infect., 9, 1077 (2003), Walker, D.K., et al.: Drug Metab. Dispos., 33, 587 (2005), Wood, A., et al.: Prog. Med. Chem., 43, 239 (2005),<br></p>Fórmula:C29D6H35F2N5OCor e Forma:NeatPeso molecular:519.70Dechloro-Rivaroxaban
CAS:Produto Controlado<p>Applications Dechloro-Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Fórmula:C19H19N3O5SCor e Forma:NeatPeso molecular:401.444-Nitro Lenalidomide
CAS:Produto Controlado<p>Impurity Lenalidomide impurity<br>Applications Lenalidomide (L328000) analog. Lenalidomide impurity; Lenalidomide intermediate.<br>References Hashimoto, Y., et al.: Bioorg. Med. Chem., 10, 461 (2002),<br></p>Fórmula:C13H11N3O5Cor e Forma:NeatPeso molecular:289.2410β-Hydroxy Naloxone
CAS:Produto Controlado<p>Impurity Naloxone EP Impurity F<br>Applications 10β-Hydroxy Naloxone is hydroxylated analog of the opioid antagonist Naloxone (N285000).<br>References Jasinski, D.R., et al.: J. Pharmacol. Exp. Ther., 157, 420 (1967), McNicholas, L.F., et al.: Drugs, 27, 81 (1984), Hasson, M.M.A., et al.: Anal. Profiles Drug Subs., 14, 453 (1985), Stowe, C., et al.: Ann. Pharmacother., 27, 447 (1993)<br></p>Fórmula:C19H21NO5Cor e Forma:NeatPeso molecular:343.37Aripiprazole N1-Oxide
CAS:Produto Controlado<p>Impurity Aripiprazole EP Impurity F<br>Stability Hygroscopic<br>Applications Aripiprazole N1-Oxide (Aripiprazole EP Impurity F) is a metabolite of anti-psychotic drug, Aripiprazole (A771000).<br>References Rowley, M., et al.: J. Med. Chem., 44, 477 ( 2001), Ozdemir, V., et al.: Curr. Opin. Invest Drugs 2002, 3, 113,,,4) Jordan, S; European Journal Pharmacol 2002, 441, 137<br></p>Fórmula:C23H27Cl2N3O3Cor e Forma:NeatPeso molecular:464.38Deferiprone-d3 3-O-β-D-Glucuronide Sodium Salt
CAS:Produto Controlado<p>Stability Very Hygroscopic<br>Applications A labelled metabolite of Deferiprone (D474000).<br>References Choudhury, R., et al.: Drug Metab. Dispos., 23, 314 (1995);<br></p>Fórmula:C13H13D3NNaO8Cor e Forma:Off-White To Light BeigePeso molecular:340.28Gabapentin-d6 Hydrochloride
CAS:Produto Controlado<p>Applications Gabapentin Hydrochloride is a salt analogue of Gabapentin-d6 (G117253), a labelled amino acid structurally related to γ-Aminobutyric Acid (GABA), designed to cross the blood brain barrier. Used as an anticonvulsant.<br>References Vollmer, K.O. et al.: Arzneim.-Forsch., 36, 830 (1986); Saletu, B., et al.: Int. J. Clin. Pharmacol. Ther. Toxicol., 24, 362 (1986)<br></p>Fórmula:C9H11D6NO2·HClCor e Forma:NeatPeso molecular:213.735,5-Diphenyl Hydantoin Sodium
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 5,5-Diphenyl Hydantoin Sodium salt reduces incidence of grand mal seizures; appears to stabilize excitable membranes perhaps through effects on Na+, K+, and Ca2+ channels.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Faucette, S., et al.: J. Pharmacol. Exp. Ther., 320, 72 (2007), Guo, D., et al.: J. Biol. Chem., 282, 36766 (2007), Merrell, M., et al.: Drug Metab. Dispos., 36, 1716 (2008),<br></p>Fórmula:C15H11N2O2·NaCor e Forma:NeatPeso molecular:274.251-Acetyl-4-(4-hydroxyphenyl)piperazine
CAS:Produto Controlado<p>Applications 1-Acetyl-4-(4-hydroxyphenyl)piperazine is an intermediate used to prepare Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo.<br>References Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)<br></p>Fórmula:C12H16N2O2Cor e Forma:WhitePeso molecular:220.272-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide
CAS:<p>Applications 2-(4-Hydroxybenzyl)-N,5-bis-(4-fluorophenyl)-5-hydroxypentanamide is an ring-opened impurity of Ezetimibe (E975000).<br>References Raman, B. et al.: J. Pharmac. Biomed. Anal., 52, 73 (2010);<br></p>Fórmula:C24H23F2NO3Cor e Forma:WhitePeso molecular:411.44(1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine
CAS:Produto Controlado<p>Applications 1-[[2-[(2-Aminophenyl)amino]-5-methyl-3-thienyl]carbonyl]-4-methyl-piperazine is an impurity of Olanzapine (O253750), a serotonin (5-HT2) and dopamine (D1/D2) receptor antagonist with anticholinergic activity.<br>References Moore, N.A., et al.: Curr. Opin Invest. Drugs, 2, 281 (1993), Baldwin, D.S. and Montgomery, S.A.: Int. Clin. Psychopharmacol., 10, 239 (1995), Tohen, M., et al.: Am. J. Psychiatry, 156, 702 (1999)<br></p>Fórmula:C17H22N4OSCor e Forma:NeatPeso molecular:330.45Thioacetic Acid
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Thiacetic Acid is a commonly used reagent in organic synthesis for the introduction of thiol groups in molecules.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Chapman, J.H. et al.: J. Chem. Soc., 579 (1950); Hoque, A., et al.: Bioorg. Med. Chem. Lett., 22, 6770 (2012)<br></p>Fórmula:C2H4OSCor e Forma:NeatPeso molecular:76.126-ethoxy-N-(pyridin-2-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:285.3699951171875Olanzapine LIP 1 Acetyl
CAS:<p>Applications Olanazpine LIP 1 Acetyl is an Olanazpine impurity. Olanazpine is an antipsychotic medicine.<br>References Perera, V., et al.: Br. J. Clin. Pharmacol., 78, 800 (2014); Pratt, N., et al.: Pharmacoepidemiol. Drug Saf., 22, 915 (2013)<br></p>Fórmula:C18H20N4OSCor e Forma:YellowPeso molecular:340.44rac Viloxazine-d5 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled Viloxazine (V312440). Antidepressant.<br>References Howe, R., et al.: J. Med. Chem., 19, 1074 (1976), Pinder, R.M., et al.: Drugs, 13, 401 (1977),<br></p>Fórmula:C13H15D5ClNO3Cor e Forma:NeatPeso molecular:278.793-(5-Nitrofurfurylideneamino)hydantoic Acid
CAS:<p>Impurity Nitrofurantoin USP Related Compound A<br>Applications 3-(5-Nitrofurfurylideneamino)hydantoic Acid, is a new derivative of 5-Nitro-2-furfural, and they are proved to be bactericidal. Nitrofurantoin USP Related Compound A.<br>References Swirska, A., et al.: Rocz. Chem., 31, 1335 (1957);<br></p>Fórmula:C8H8N4O6Cor e Forma:YellowPeso molecular:256.17(1RS)-1-(6-Methoxy-2-naphthyl)ethanol (Naproxen Impurity K)
CAS:Produto Controlado<p>Impurity Naproxen EP Impurity K<br>Applications Naproxen impurity K.<br>References Boynton, C., et al.: J. Clin. Pharmacol., 28, 512 (1988), Li, J., et al.: J. Med. Chem., 39, 1846 (1996), Monser, L., et al.: J. Pharm. Biomed. Anal., 27, 851 (2002),<br></p>Fórmula:C13H14O2Cor e Forma:White To Light YellowPeso molecular:202.25Empagliflozin
CAS:<p>Stability Hygroscopic<br>Applications Empagliflozin is a novel, potent and selective SGLT-2 inhibitor. It improves glycaemic control syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Fórmula:C23H27ClO7Cor e Forma:White To Off-WhitePeso molecular:450.91Hydroxy Ritonavir
CAS:Produto Controlado<p>Impurity Ritonavir EP Impurity E<br>Applications Hydroxy Ritonavir (Ritonavir EP Impurity E) is a metabolite of Ritonavir (R535000), HIV-1 protease inhibitor. It is a COVID19-related research product.<br>References Eagling, V., et al.: Br. J. Clin. Pharmacol., 48, 543 (1999), Eagling, V., et al.: Xenobiotica, 32, 1 (2002), Meaden, E., et al.: J. Antimicrob. Chemother., 50, 583 (2002), Treijtel, N., et al.: Drug Metab. Dispos., 33, 1325 (2005),<br></p>Fórmula:C37H48N6O6S2Cor e Forma:NeatPeso molecular:736.941-[3-(Trifluoromethyl)pyridin-2-yl]piperazine hydrochloride
CAS:Pureza:97.0%Peso molecular:267.67999267578125(E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
CAS:Produto ControladoFórmula:C19H18IN3OCor e Forma:White To Light YellowPeso molecular:431.27Telmisartan
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Telmisartan is an angiotensin II receptor antagonist.<br>References Wienen, W., et al.: Brit. J. Pharmacol., 110, 245 (1993), Neutel, J.M., and Smith, D.H.G.: Adv. Ther., 15, 206 (1998)<br></p>Fórmula:C33H30N4O2Cor e Forma:NeatPeso molecular:514.62Ethyl 4[[6-(4-Carbamimidoylphenoxy)hexyl]oxy]benzoate Hydrochloride
<p>Applications Ethyl 4[[6-(4-Carbamimidoylphenoxy)hexyl]oxy]benzoate is an impurity of Hexamidine Diisetionate (H294205), which is an amidine compound used in the treatment of amyloid-related diseases; it is also used as preservative in cosmetics as an antispetic.<br>References Siddall, T., et al.: J. Org. Chem., 31, 3719 (1966)<br></p>Fórmula:C22H28N2O4·HClCor e Forma:NeatPeso molecular:384.47 +(36.46)4-(6,7-DIMETHOXY-QUINOLIN-4-YLOXY)-PHENYLAMINE
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:296.32598876953125Ambrisentan Methyl Ester
CAS:Produto Controlado<p>Applications (S)-Methyl 2-((4,6-dimethylpyrimidin-2-yl)-oxy)-3-methoxy-3,3-diphenylpropanoate is a useful intermediate in the preparation of Ambrisentan. Ambrisentan is an Antihypertensive. Ambrisentan Impurity (A575860).<br>References Peng, X., et al.: J. Org. Chem., 77, 701 (2012), Riechers, H., et al.: J. Med. Chem., 39, 2123 (1996), Billman, G.E., et al.: Curr. Opin. Invest. Drugs, 3, 1483 (2002), Vatter, H., et al.: Clin. Neuropharmacol., 26, 73 (2003)<br></p>Fórmula:C23H24N2O4Cor e Forma:Off-WhitePeso molecular:392.454-(Trifluoromethyl)aniline
CAS:Produto Controlado<p>Impurity Leflunomide EP Impurity A; Leflunomide USP Related Compound A<br>Applications 4-(Trifluoromethyl)aniline (Leflunomide EP Impurity A; Leflunomide USP Related Compound A) is a 4-Substituted aniline derivatives exert special hematotoxicity on the red blood cells and induce leukocytosis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Weber, W., et al.: Pharmacol. Rev., 37, 25 (1985), Hein, D., et al.: Carcinogenesis, 14, 1633 (1993), Payton, M., et al.: Microbiology, 147, 1137 (2001), Mushtaq, A., et al.: J. Biol. Chem., 277, 12175 (2002),<br></p>Fórmula:C7H6F3NCor e Forma:NeatPeso molecular:161.12Ethyl 4-Acetamidobenzoate
CAS:Produto Controlado<p>Applications Ethyl 4-acetamidobenzoate is a reagent that is used in the synthesis of DAMPA-d3, which is a labeleld antitumor agent.<br>References Martinelli, J.E., et al.: J. Med. Chem., 22, 869 (1979);<br></p>Fórmula:C11H13NO3Cor e Forma:Off-WhitePeso molecular:207.235-Nitro-2-furfuraldazine
CAS:Produto Controlado<p>Impurity Nitrofurazone USP Related Compound A<br>Applications 5-Nitro-2-furfuraldazine is an impurity in the synthesis of Nitrofurazone (N493880), anti-infective (topical). Antimicrobial. Nitrofurazone USP Related Compound A<br>References Morris, et al.: Cancer Res., 29, 2145 (1969), Sanderson, H., et al.: Toxicol. Lett., 144, 383 (2003),<br></p>Fórmula:C10H6N4O6Cor e Forma:NeatPeso molecular:278.178(3’S)-ent-Ezetimibe
CAS:<p>Applications An enantiomeric impurity of Ezetimibe (E975005), an antihyperlipoproteinemic and cholesterol absorption inhibitor.<br></p>Fórmula:C24H21F2NO3Cor e Forma:WhitePeso molecular:409.43Pericyazine
CAS:Produto Controlado<p>Applications Psychotherapeutic phenothiazine. Antipsychotic.<br>References Schafer, et al.: Toxicol. Appl. Pharmacol., 21, 315 (1972), Kaye, J., et al.: Br. J. Clin. Pharmacol., 56, 569 (2003), Tschoner, A., et al.: Pharmacopsychiatry, 42, 29 (2009),<br></p>Fórmula:C21H23N3OSCor e Forma:Light Yellow To YellowPeso molecular:365.49NAP 226-90
CAS:<p>Impurity Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C<br>Applications NAP 226-90 (Rivastigmine EP Impurity A; Rivastigmin USP Related Compound C) is a S-Enantiomer metabolite of Rivastigmine, a brain selective acetylcholinesterase inhibitor.<br>References Rosler, M., et al.: Br. Med. J., 318, 633 (1999), Jann, M., et al.: Clin. Pharmacokinet., 41, 719 (2002), Frankfort, S., et al.: Int. J. Clin. Pract., 60, 646 (2006),<br></p>Fórmula:C10H15NOCor e Forma:WhitePeso molecular:165.234-Cyano-3-trifluoromethylphenylisothiocyanate
CAS:Produto ControladoFórmula:C9H3F3N2SCor e Forma:NeatPeso molecular:228.192-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol
CAS:Produto Controlado<p>Applications 2-(4-Methyl-2-phenyl-1-piperazinyl)-3-pyridinemethanol is an impurity found in Mirtazapine (M365000). Mirtazapine Impurity B.<br></p>Fórmula:C17H21N3OCor e Forma:White To Off-WhitePeso molecular:283.371-Hydroxycyclopentyl 2-chlorophenyl Ketone
CAS:Produto ControladoFórmula:C12H13ClO2Cor e Forma:Colourless To Light YellowPeso molecular:224.682,3,4-Trimethoxybenzaldehyde
CAS:Produto Controlado<p>Applications 2,3,4-Trimethoxybenzaldehyde is a trimethoxylated aromatic aldehyde. 2,3,4-Trimethoxybenzaldehyde is an impurity of the anti-anginal drug Trimetazidine (T795610).<br>References Medenica, M.B. et al.: J. Chrom. Sci., 46, 430 (2008);<br></p>Fórmula:C10H12O4Cor e Forma:Off-WhitePeso molecular:196.204-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-ol
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:319.7200012207031Argatroban monohydrate
CAS:Produto ControladoFórmula:C23H36N6O5S·H2OCor e Forma:NeatPeso molecular:526.65Nilotinib-d6
CAS:Produto Controlado<p>Applications Nilotinib-d6, is the labeled analogue of Nilotinib (N465300), which might be useful in treatment of chronic myelogenous leukemia. It is a COVID19-related research product.<br>References Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),<br></p>Fórmula:C282H6H16F3N7OCor e Forma:Off-White To Light BeigePeso molecular:535.55Amisulpride N-Oxide
CAS:Produto Controlado<p>Impurity Amisulpride EP Impurity F<br>Applications Amisulpride N-Oxide is an impurity of Amisulpride (A633250). Amisulpride N-Oxide was identified as a photodegradation product of Amisulpride. Amisulpride EP Impurity F<br>References Moulin, A., et al.: Eur. J. Drug Metab. Pharmcokinet., 3, 507 (1991), Chatterjee, B., et al.: J. Biotechnol., 3, 235 (2008), Breier, A., et al.: J. Pharm. Biomed. Anal., 46, 250 (2008),<br></p>Fórmula:C17H27N3O5SCor e Forma:White To Off-WhitePeso molecular:385.48Diaveridine
CAS:Produto Controlado<p>Applications Diaveridine is a dihydrofolate reductase inhibitor. It is used in veterinary medicine as a drug for its anticoccidial properties and its function as an antibacterial synergist.<br>References Wang, H., et al.: J. Chromatogr. B., 965, 91 (2014); Wang, X., et al.: Regul. Toxicol. Pharm., 73, 232 (2015); Sporri, S., et al.: Food. Addit. Contam. A., 31, 806 (2014)<br></p>Fórmula:C13H16N4O2Cor e Forma:NeatPeso molecular:260.29(R)-(+)-5’-Hydroxyphenyl Carvedilol
CAS:<p>Applications An optically active metabolite of Carvedilol (C184625), a nonselective ß-adrenergic blocker with α1-blocking activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sponer, G., et al.: J. Cardiovasc. Pharmacol., 9, 317 (1987), Fujimaki, M., ET AL.: Xenobiotica, 20, 1025 (1990), Ruffolo, R., et al.: Eur. J. Clin. Pharmacol., 38, S82 (1990), Schaefer, W.H., et al.: Drug Metab. Dispos., 26, 10, 958 (1998),<br></p>Fórmula:C24H26N2O5Cor e Forma:NeatPeso molecular:422.47Reserpine
CAS:Produto Controlado<p>Applications An indole alkaloid found in Rauwolfia serpentina. Inhibits vesicular uptake of catecholamines and serotonin. Reserpine is reasonably anticipated to be a human carcinogen. Antihypertensive.<br>References Muller, J.M., et al.: Experientia, 8, 338 (1952), Schirmer, R.E., et al.: Anal. Profiles Drug Subs., 4, 384 (1975), Diener, R.M., et al.: Toxicol. Pathol., 8, 1 (1980),<br></p>Fórmula:C33H40N2O9Cor e Forma:Off-WhitePeso molecular:608.68Nilotinib N-Oxide
CAS:Produto Controlado<p>Applications A metabolite of Nilotinib (N465300). It is a COVID19-related research product.<br></p>Fórmula:C28H22F3N7O2Cor e Forma:NeatPeso molecular:545.52Tert-Butyl 2-(pyridin-4-yl)acetate
CAS:Pureza:95.0%Cor e Forma:LiquidPeso molecular:193.24600219726562Ref: 10-F335907
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarKAD-1229 Calcium Hydrate
CAS:Produto ControladoFórmula:C19H24NO3·Ca·2H2OCor e Forma:NeatPeso molecular:704.91(S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid
CAS:Produto Controlado<p>Impurity Ambrisentan Hydroxy Acid Impurity<br>Applications (S)-2-Hydroxy-3-methoxy-3,3-diphenylpropionic Acid is used in analytical studies for chiral discrimination of α-functionalized acids. Ambrisentan Hydroxy Acid Impurity<br>References Jain, N., et al.: Tetrahedron, 70, 4343 (2014)<br></p>Fórmula:C16H16O4Cor e Forma:NeatPeso molecular:272.30N,N'-Dicyclohexylurea
CAS:Produto Controlado<p>Impurity Lomustine USP Related Compound C<br>Applications N,N'-Dicyclohexylurea,is a substituted Urea (U822500) compound, which has shown to be a potent inhibitor of juvenile hormone epoxide hydrolase (JHEH) of the tobacco hornworm M. sexta. Lomustine USP Related Compound C.<br>References Garriga, M., et al.: Chemosphere, 82, 1604 (2011)<br></p>Fórmula:C13H24N2OCor e Forma:Light YellowPeso molecular:224.34Dasatinib Dimeric Impurity
CAS:Produto ControladoFórmula:C36H34Cl2N12O2S2Cor e Forma:White To BeigePeso molecular:801.77Bupivacaine Hydrochloride
CAS:Produto Controlado<p>Applications Bupivacaine HCl (cas# 18010-40-7) is a useful research chemical.<br></p>Fórmula:C18H28N2O·ClHCor e Forma:NeatPeso molecular:324.892-(1-Hydroxyethyl) Promazine-d4
CAS:Produto Controlado<p>Applications A labelled metabolite of Acepromazine (A130900).<br>References Cossum, P., et al.: Drug Dispos., 9, 321 (1988), Stowell, L., et al.: J. Anal. Toxicol., 22, 166 (1998),<br></p>Fórmula:C19H20D4N2OSCor e Forma:NeatPeso molecular:332.5rac-cis-N-Desmethyl Sertraline-d4 Hydrochloride
CAS:Produto Controlado<p>Applications A labelled metabolite of Sertraline. N-Desmethyl Sertraline is significantly less active analogue as compared to the methylated compound, Sertraline.<br>References Welch, W.M., et al.: J. Med. Chem. 27, 1508 (1984)<br></p>Fórmula:C16H12D4Cl3NCor e Forma:NeatPeso molecular:332.69Anagliptin
CAS:Produto Controlado<p>Applications Anagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that suppresses proliferation of vascular smooth muscles and monocyte inflammatory reaction. It also attenuates atherosclerosis in male apolipoprotein E-deficient mice.<br>References Ervinna, N., et al.: Endocrinology, 154, 1260 (2013); Furuta, S., et al.: Eur. J. Drug Metab. Ph., 38, 87 (2013)<br></p>Fórmula:C19H25N7O2Cor e Forma:NeatPeso molecular:383.45ent-Levobunolol Hydrochloride (R-Bunolol Hydrochloride)
CAS:Produto Controlado<p>Applications A non-selective ß-adrenoceptor antagonist used as an anticonvulsant. The enantiomer of Levobunolol (L335000).<br>References Kaplan, H.R., et al.: Eur. J. Pharm., 16, 237 (1971), DiCarlo,F.J., et al.: Clin. Pharm. Ther., 22, 858 (1977)<br></p>Fórmula:C17H25NO3·ClHCor e Forma:NeatPeso molecular:327.85Omeprazole-d3 Sulfide
CAS:Produto ControladoFórmula:C172H3H16N3O2SCor e Forma:NeatPeso molecular:332.44AR-C133913XX
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications AR-C133913XX is an metabolte of Ticagrelor (T437700) which is the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Ticagrelor is used in the treatment of acute coronary syndromes (ACS).<br>References Matetzky, S., et al.: Circulation, 109, 3171 (2004); Bassand, J., et al.: Eur. Heart J., 28, 1598 (2007); Jakubowski, J., et al.: Cardiovasc. Drug Rev., 25, 357 (2007)<br></p>Fórmula:C14H22N6O4SCor e Forma:NeatPeso molecular:370.433-(3,5-Dimethyl-pyrazol-1-ylmethyl)-phenylamine
CAS:Fórmula:C12H15N3Pureza:98%Cor e Forma:Low Melting SolidPeso molecular:201.273Nortilidine-d3 Hydrochloride
CAS:Produto ControladoFórmula:C162H3H18NO2·ClHCor e Forma:NeatPeso molecular:298.82Clozapine
CAS:Produto Controlado<p>Applications An antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Stille, et al: Farnaco, Ed. Prat., 26, 603 (1971), Hane, J.M., et al.: Psychopharmacol. Bull., 24, 62 (1988), Meltzer, H.Y.: J. Clin. Psychiatry, 55, Suppl. B, 47 (1994)<br></p>Fórmula:C18H19ClN4Cor e Forma:Off-WhitePeso molecular:326.82Lenalidomide-d5
CAS:Produto Controlado<p>Applications Lenalidomide-d5, is the labeled analogue of Lenalidomide (L328000), an immunomodulatory drug; analog of Thalidomide.<br>References Bartlett, J.B., et al.: Nature Rev., 4, 314 (2004), Mitsiades, C.S., et al.: Curr. Opin. Invest. Drugs, 5, 635 (2004), List, A., et al.: N. Engl. J. Med., 352, 549 (2005),<br></p>Fórmula:C13H8D5N3O3Cor e Forma:Off-WhitePeso molecular:264.2910-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide
CAS:Produto Controlado<p>Applications 10-Acetoxy-5H-dibenz[b,f]azepine-5-carboxamide is an intermediate in the synthesis of Oxacarbazepine (O869250) related compounds.<br></p>Fórmula:C17H14N2O3Cor e Forma:NeatPeso molecular:294.30(±)-Pramipexole
CAS:<p>Applications (±)-Pramipexole is a recemic analogue of (S)-Pramipexole (P700755), a dopamine-D2-receptor agonist. Antiparkinsonian.<br>References Schilling, J.C., et al.: Clin. Pharmacol. Ther., 51, 541 (1992), Kieburtz, K., et al.: J. Am. Med. Assoc., 278, 125 (1997)<br></p>Fórmula:C10H17N3SCor e Forma:NeatPeso molecular:211.33Eperisone Hydrochloride
CAS:Produto Controlado<p>Applications A spasmolytic agent related structurally to Tolperisone (T535475). Muscle relaxant (skeletal).<br>References Catterall, W., et al.: J. Biol. Chem., 256, 892 (1981), Farkas, S., et al.: Br. J. Pharmacol., 114, 1193 (1995), Xing, J., et al: Brain Res., 901, 128 (2001), Sakaue, A., et al.: J. Pharmacol. Sci., 95, 181 (2004),<br></p>Fórmula:C17H25NO·ClHCor e Forma:White To Off-WhitePeso molecular:295.85Captopril-d3
CAS:Produto Controlado<p>Applications Orally active angiotensin-converting enzyme (ACE) inhibitor.<br>References Rubin, B., et al.: Eur. J Pharmacol., 51, 377 (1978),<br></p>Fórmula:C9D3H12NO3SCor e Forma:White SolidPeso molecular:220.30
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