Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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Vioxx-d5 (Major)
CAS:Produto Controlado<p>Applications A selective labelled cyclooxygenase-2 (COX-2) inhibitor. Use as an anti-inflammatory, analgesic.<br>References Catalla-Lawson, F., et al.: J. Pharmacol. Exp. Ther., 289, 735 (1999), Ehrich, E.W., et al.: Clin. Pharmacol. Ther., 65, 336 (1999), Langman, M.J., et al.: J. Am. Med. Assoc., 282, 1929 (1999),<br></p>Fórmula:C172H5H9O4SCor e Forma:NeatPeso molecular:319.387Teflubenzuron
CAS:Produto Controlado<p>Applications Teflubenzuron is an benzoylphenylurea chitin synthesis inhibitor used to control a wide range of insect pests and mites in fruit, vegetable, cereal and seed crops. Teflubenzuron is used in cannabis testing kits as a component of pesticide mixes (P698240).<br>References Carro, A.M., et al.: J. Separat. Sci., 35, 2866 (2012); Brock, T.C.M., et al.: Environ. Sci. Pollu. Res., 19, 3610 (2012);<br></p>Fórmula:C14H6Cl2F4N2O2Cor e Forma:Off-WhitePeso molecular:381.111-Chloroadamantane
CAS:<p>Impurity Adamantane EP Impurity A<br>Stability Light Sensitive<br>Applications 1-Chloroadamantane, an adamantane derivative shown to exhibit virucidal activity against the Newcastle disease virus in chick embryo fibroblasts. (Adamantane EP Impurity A)<br>References Aigami, K., et al.: J. Med. Chem., 18, 713 (1975)<br></p>Fórmula:C10H15ClCor e Forma:NeatPeso molecular:170.683-(9H-Carbazol-4-yloxy)-1,2-propanediol
CAS:Produto Controlado<p>Applications 3-(9H-Carbazol-4-yloxy)-1,2-propanediol is used in the synthesis of carvedilol, a β-adrenergic blocking agent.<br>References Naidu, K. et al.: Org. Chem. An Indian J., 6, 171 (2010);<br></p>Fórmula:C15H15NO3Cor e Forma:NeatPeso molecular:257.283-(3-Methoxyphenyl)-1-(p-tolyl)-1H-pyrazole-4-carboxylic acid
CAS:Pureza:98%Peso molecular:308.3370056152344(2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile
CAS:Produto Controlado<p>Applications (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes.<br>References Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008); Villhauer, E. B., et al.: J. Med. Chem., 46, 2774 (2003);<br></p>Fórmula:C7H9ClN2OCor e Forma:NeatPeso molecular:172.61Tenoxicam-d4
CAS:Produto Controlado<p>Applications Labelled Tenoxicam (T019500). Nonsteroidal anti-inflamatory agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bird, H.A., et al.: Curr. Med. Res. Opin., 8, 9 (1982), Gonzalez, J.P., et al.: Drugs, 34, 289 (1987), Al-Obaid, A.M., et al.: Anal. Profiles Drug Subs. Excip., 22, 431 (1993),<br></p>Fórmula:C13D4H7N3O4S2Cor e Forma:Light YellowPeso molecular:341.399Amisulpride
CAS:Produto Controlado<p>Applications Amisulpride is a neuroleptic agent, an analogue of Sulpiride (S689145). Amisulpride is used as an antipsychotic. Amisulpride is a dopamine receptor antagonist.<br>References Protais, P., et al.: Neuropharmacol., 24, 861 (1985), Perrault, G., et al.: J. Pharmacol. Exp. Ther., 280, 73 (1997),<br></p>Fórmula:C17H27N3O4SCor e Forma:WhitePeso molecular:369.481-(3-Carboxy-2-pyridyl)-4-methyl-2-phenylpiperazine
CAS:Produto Controlado<p>Applications Mirtazapine (M365000) impurity.<br>References Reddy, T. et al.; J. Liq. Chromatogr. R. T. 31, 1204 (2008)<br></p>Fórmula:C17H19N3O2Cor e Forma:NeatPeso molecular:297.358-tert-butyl-4-(thiophene-2-carbonyl)-1-oxa-4-azaspiro[4.5]decane-3-carboxylic acid
CAS:Pureza:95.0%Peso molecular:351.4599914550781N-Nitroso Duloxetine
CAS:Fórmula:C18H18N2O2SCor e Forma:Colourless To Light YellowPeso molecular:326.4137-Hydroxy Chlorpromazine-d6 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled analogue of 7-Hydroxychlorpromazine, the 7-hydroxy analogue and a major metabolite of the atypical antipsychotic Chlorpromazine (C424750).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jori, A. et al.: Int. J. Neuropharmacol., 5, 435 (1966); Shavit, S. et al.: Comm. Psychopharmacol., 4, 495 (1980);<br></p>Fórmula:C17H14D6Cl2N2OSCor e Forma:NeatPeso molecular:377.36Empagliflozin Methyl Acetate
CAS:<p>Applications Empagliflozin Methyl Acetate is an impurity of Empagliflozin (E521510), which is a novel, potent and selective SGLT-2 inhibitor. It improves glycaemic control syndrome in diabetic rats.<br>References Thomas, L., et al.: Diabetes. Obesity. Metabol. 14, 94 (2012); Grempler, R., et al.: Diabetes. Obesity. Metabol., 14, 83 (2012);<br></p>Fórmula:C25H29ClO8Cor e Forma:White To Off-WhitePeso molecular:492.95Cabergoline N-Oxide
Produto Controlado<p>Applications The N-oxide of Cabergoline (C050000), a dopamine D2-receptor agonist.<br>References Brambilla, E., et al.: Eur. J. Med. Chem., 24, 421 (1989), Ferrari, C., et al.: J. Clin. Endocrinol. Metab., 68, 1201 (1989), Hutton, J.T., et al.: Neurology, 46, 1062 (1996)<br></p>Fórmula:C26H37N5O3Cor e Forma:NeatPeso molecular:467.6Isoxsuprine Hydrochloride
CAS:Produto Controlado<p>Applications A vasilodator drug. It is used in veterinary medicine for the treatment of navicular syndrome and laminitis in horses. It has been shown to be a β-adrenoreceptor antagonist with β-adrenoreceptor agonistic properties, with both characteristics contributing to vasodilation and uterine relaxation. Studies suggest that ut may be useful as a as a tocolytic agent in the treatment of preterm labour.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Erkert, R.S. et al.: J. Vet. Pharmacol. Therap., 25, 81 (2002); Giorgino, F.L. et al.: Arzneim. Forsch., 60, 415 (2010);<br></p>Fórmula:C18H23NO3·ClHCor e Forma:White To Off-WhitePeso molecular:337.84tert-Butyl (R)-3-Aminopiperidine-1-carboxylate
CAS:Produto Controlado<p>Applications tert-Butyl (R)-3-Aminopiperidine-1-carboxylate, is an heterocyclic building block used for the synthesis of more complex pharmaceutical compounds. It is also found to act as a γ-secretase modulators, and a potent structure for lowering Aβ42 production in both in vitro and in vivo.<br>References Kobayashi, T., et al.: Bioorg. Med. Chem. Lett., 24, 378 (2014);<br></p>Fórmula:C10H20N2O2Cor e Forma:NeatPeso molecular:200.282-Methylindazole-3-carboxylic Acid
CAS:Produto Controlado<p>Applications A reagent used to synthesize 5-HT2A and 5-HT3 receptor ligands for use in treating CNS-related disorders.<br>References Bermudez, J., et al.: J. Med. Chem., 33, 1924 (1990),<br></p>Fórmula:C9H8N2O2Cor e Forma:NeatPeso molecular:176.17Bis[(2-guanidino-4-thiazolyl)methyl]disulfide (85%) (Famotidine Impurity)
CAS:Produto ControladoFórmula:C10H14N8S4Cor e Forma:Off-WhitePeso molecular:374.53Timolol Maleate
CAS:<p>Applications Antihypertensive; antiarrhythmic (class II); antianginal; antiglaucoma agent.<br>References Wasson, et al.: J. Med. Chem., 15, 651 (1972), Franciosa, et al.: Clin. Pharmacol. Ther., 13, 138 (1972), Heel, R.C., et al.: Drugs, 17, 38 (1979), Rofman, B.A., et al.: Hypertension, 2, 643 (1980), Mazzo, D.J., et al.: Anal. Profiles Drug Subs., 16, 641 (1987),<br></p>Fórmula:C13H24N4O3S·C4H4O4Cor e Forma:NeatPeso molecular:432.49β-(Cyanoimino)-1-piperidinepropanamide
CAS:Produto Controlado<p>Impurity Minoxidil EP Impurity C<br>Applications β-(Cyanoimino)-1-piperidinepropanamide (Minoxidil EP Impurity C) is an impurity in the synthesis of Minoxidil (M345000), used as an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels.<br>References Franz, T.J., et al.: Arch. Dermatol., 121, 203 (1985), Gadwood, R.C., et al.: Annu. Rep. Med. Chem., 24, 187 (1989), Hautala, T., et al.: Biochem. J., 283, 51 (1992),<br></p>Fórmula:C9H14N4OCor e Forma:NeatPeso molecular:194.23N-Acetyl-(+)-Pseudoephedrine
CAS:Produto Controlado<p>Applications N-Acetyl-(+)-Pseudoephedrine is the N-acetylated analogue of the non-selective adrenergic agonist (+)-Pseudoephedrine (P839350).<br>References Tanaka, K.: Yakug. Zas., 70, 220 (1950); Rodriguez, M. et al.: Org. Biomol. Chem., 3, 2026 (2005);<br></p>Fórmula:C12H17NO2Cor e Forma:WhitePeso molecular:207.272-Hydroxymethyl Loratadine
CAS:Produto Controlado<p>Impurity Loratadine 2-Hydroxymethyl Impurity (USP)<br>Applications A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor. Loratadine 2-Hydroxymethyl Impurity (USP).<br>References Okamoto, T., et al.: Chem. Pharm. Bull ., 7, 130 (1959), Eyjolfsson, R., et al.: Pharmazie, 58, 154 (2003),<br></p>Fórmula:C23H25ClN2O3Cor e Forma:NeatPeso molecular:412.912-Carboxybenzoyl Amlodipine
CAS:Produto Controlado<p>Impurity Amlodipine EP Impurity H<br>Applications Amlodipine Besilate (A633500) impurity. Used in the process for preparing Amlodipine benzenesulfonate. Amlodipine EP Impurity H<br></p>Fórmula:C28H29ClN2O8Cor e Forma:NeatPeso molecular:556.99Thioridazine-d3 Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Dopamine receptor blocker; parent compound of sulforidazine and mesoridazine. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Fórmula:C21D3H23N2S2·ClHCor e Forma:NeatPeso molecular:410.05Desethylcarbamoyl Cabergoline
CAS:Produto Controlado<p>Impurity Cabergoline EP Impurity D<br>Applications A metabolite of Cabergoline, having affinity for D1 and D2 dopamine receptors in rat striatum<br>References Battaglia, R., et al.: Xenobiotica, 23, 1377 (1993), Miyagi, M., et al.: Biol. Pharm. Bull., 19, 1210 (1996),<br></p>Fórmula:C23H32N4OCor e Forma:Beige SolidPeso molecular:380.53Varenicline N-Glucoside
CAS:Produto Controlado<p>Applications A metabolite of Varenicline. Metabolite M7.<br>References Dow, J., et al.: Drug Metab. Dispos., 22, 738 (1994), Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005),<br></p>Fórmula:C19H23N3O5Cor e Forma:NeatPeso molecular:373.40(1S)-4,5-Dimethoxy-1-[(methylamino)methyl]benzocyclobutane Hydrochloride
CAS:Produto ControladoFórmula:C12H17NO2·ClHCor e Forma:NeatPeso molecular:243.736-Chloro-pyrimidine-2,4-diamine
CAS:Produto Controlado<p>Impurity Minoxidil EP Impurity B<br>Applications 6-Chloro-pyrimidine-2,4-diamine (cas# 156-83-2) is a compound useful in organic synthesis.<br></p>Fórmula:C4H5ClN4Cor e Forma:WhitePeso molecular:144.56Azobenzene
CAS:<p>Applications Impurity in the production of Phenylbutazone (P319570). Dyes and metabolites.<br>References Chung, K., et al.: Mutation Res., 114, 269 (1983), Kawanishi, S., et al.: J. Biol. Chem., 261, 5952 (1986), Floyd, R., et al.: Carcinogenesis, 11, 1447 (1990), Shibutani, S., et al.: Nature, 349, 431 (1991),<br></p>Fórmula:C12H10N2Cor e Forma:NeatPeso molecular:182.22Meloxicam- 13CD3
CAS:Produto Controlado<p>Applications iMeloxicam- 13CD3 is an isotopic labeled form of Meloxicam(M216100). Meloxicam is a preferential cyclooxygenase (COX-2) inhibitor. Sudoxicam and Meloxicam are nonsteroidal anti-inflammatory drugs (NSAIDs) from the enol-carboxamide class.<br>References Hawkey, C., et al.: Br. J. Rheumatol., 35, Suppl. 1, 1 (1996), Fleischmann, R., et al.: Expert Opin. Pharmacother., 3, 1501 (2002),<br></p>Fórmula:C1313CH10D3N3O4S2Cor e Forma:Off-White To Light BrownPeso molecular:355.412-Chloro-5-(5-Chloro-2-thienyl)pyridine
CAS:Fórmula:C9H5Cl2NSPureza:97.0%Cor e Forma:SolidPeso molecular:230.11Candoxatril
CAS:<p>Candoxatril is an inhibitor neutral endopeptidase (NEP).</p>Fórmula:C29H41NO7Pureza:97.73% - 99.94%Cor e Forma:SolidPeso molecular:515.642-Oxo-ivabradine Hydrochloride
CAS:Produto ControladoFórmula:C27H34N2O6·ClHCor e Forma:NeatPeso molecular:519.03N-Demethyl Vandetanib
CAS:<p>Applications A major metabolite of Vandetanib (V097100).<br>References Gustafson, D.L. et al.: J. Pharmacol. Exp. Therap., 318, 872 (2006); Weil, A. et al.: Clin. Pharmakin., 49, 607 (2010); Stephen, R. et al.: J. Med. Chem., 45, 1300 (2002);<br></p>Fórmula:C21H22BrFN4O2Cor e Forma:NeatPeso molecular:461.3272-cyclopropyl-4-quinolinecarboxylic acid hydrate
CAS:Pureza:95.0%Cor e Forma:SolidPeso molecular:231.25100708007812Saxagliptin Hydrate
CAS:Produto Controlado<p>Applications Saxagliptin Hydrate is a selective and reversible dipeptidyl peptidase-4 (DPP4) inhibitor that may be used to develop treatment for type 2 diabetes.<br>References Gu, S., et al.: PLoS One. 11, e0167190 (2016); Dave, D. J.: J Pharmacol Pharmacother 2, 230 (2011)<br></p>Fórmula:C18H25N3O2·H2OCor e Forma:NeatPeso molecular:333.43Vadadustat
CAS:<p>Applications Vadadustat is a novel HIF (Hypoxia-inducible factor) stabilizer. It provides an effective anemia treatment in nondialysis-dependent chronic kidney disease.<br>References Pergola, P., et al.: Kidney Int., 90, 1115 (2016);<br></p>Fórmula:C14H11ClN2O4Cor e Forma:BeigePeso molecular:306.70rac-trans Paroxol
CAS:Produto Controlado<p>Applications Racemic Paroxetine intermediate.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C13H18FNOCor e Forma:NeatPeso molecular:223.293-Dehydroxy Salbutamol
CAS:Produto Controlado<p>Impurity Levalbuterol USP Related Compound B; Salbutamol EP Impurity C<br>Applications 3-Dehydroxy Salbutamol (Levalbuterol USP Related Compound B; Salbutamol EP Impurity C) is an isoprenaline based selective stimulants of β-adrenergic receptors in bronchial muscles.<br>References Hartley, D., et al.: Nature., 219, 5156 (1968);<br></p>Fórmula:C13H21NO2Cor e Forma:NeatPeso molecular:223.313-Ethyl-2-imine Meloxicam
CAS:Produto Controlado<p>Applications Meloxicam (M216100) impurity.<br></p>Fórmula:C16H17N3O4S2Cor e Forma:Light YellowPeso molecular:379.45Oxcarbazepine-D4 (Major)
CAS:Produto Controlado<p>Applications A labelled metabolite of Eslicarbazepine acetate, (BIA 2-093), a novel central nervous system drug. A keto derivative of Carbamazepine. Used as an anticonvulsant.Only available as a mixture of deuterated material:d-1: 1%d-2: 9%d-3: 35%d-4: 55%<br>References Dam., M., et al.: Epilepsy Res., 3, 70 (1989), Beydoun, A., et al.: Expert Opin. Pharmacother., 3, 59 (2001),<br></p>Fórmula:C152H4H8N2O2Cor e Forma:Light Orange Colour PowderPeso molecular:256.29Rotigotine
CAS:<p>Rotigotine (1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-) is an antiparkinson agent and dopamine receptor agonist.</p>Fórmula:C19H25NOSPureza:99.04% - 99.88%Cor e Forma:SolidPeso molecular:315.474-(4-Methylpiperazinomethyl)benzoic Acid, Dihydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-(4-Methylpiperazinomethyl)benzoic Acid, Dihydrochloride (cas# 106261-49-8) is a compound useful in organic synthesis.<br></p>Fórmula:C13H18N2O2·2ClHCor e Forma:NeatPeso molecular:307.22Ref: 10-F609006
1gA consultar2gA consultar5gA consultar100mgA consultar250mgA consultar500mgA consultarN-[4-(2,4,6-TRIMETHYLPHENYL)-2-THIAZOLYL]-4-PYRIDINECARBOXAMIDE
CAS:Pureza:97.0%Peso molecular:323.41000366210941-Amino-3-adamantanol
CAS:Produto Controlado<p>Applications Reagent used in the preparation of Vildagliptin.<br>References Fukushima, H., et al.: Bioorg. Med. Chem., 16, 4093 (2008), Anand, R., et al.: J. Med. Chem., 52, 1602 (2009),<br></p>Fórmula:C10H17NOCor e Forma:NeatPeso molecular:167.25Perampanel
CAS:Produto Controlado<p>Applications Perampanel is a novel, noncompetitive AMPA receptor antagonist for the treatment of epilepsy. Also in the treatment of primary generalized tonic-clonic seizures in idiopathic generalized epilepsy. Perampanel is a selective non-competitive α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor antagonist that reduces neuronal excitation (1,2,3,4).<br>References (1) Shih, J., et al.: Therap. Clinical Risk Management, 9, 285 (2013)(2) Rogawski, M. A., et al.: Epilepsy Curr., 11, 56 (2011)(3) Franco, V., et al.: Ther Drug Monit. 38, 744 (2016) (4) Rudzinski, L. A., et al.: J Investig Med. 64, 1087 (2016)<br></p>Fórmula:C23H15N3OCor e Forma:Light YellowPeso molecular:349.38S-Hydroxy Topiramate
CAS:Produto Controlado<p>Applications A metabolite of Topiramate.<br>References Maryanoff, B., et al.: J. Med. Chem., 30, 880 (1987), Shank, R., et al.: Epilepsia, 35, 450 (1994), Streeter, A., et al.: Drug Metab. Disp., 23, 90 (1995),<br></p>Fórmula:C12H21NO9SCor e Forma:Off-White To BeigePeso molecular:355.363-(1-Methanesulfonyl-3,5-dimethyl-1 H -pyrazol-4-yl)-propionic acid ethyl ester
CAS:Fórmula:C11H18N2O4SPureza:97%Cor e Forma:SolidPeso molecular:274.34Iloperidone-d3
CAS:Produto Controlado<p>Applications Labelled Iloperidone. Combined dopamine (D2) and serotonin (5HT2) receptor antagonist. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sainati, S.M., et al.: J. Clin. Pharmacol., 35, 713 (1995), Szewczak, M.R., et al.: J. Pharmacol. Exp. Ther., 274, 1404 (1995), Kongsamut, S., et al.: Eur. J. Pharmacol., 317, 417 (1996)<br></p>Fórmula:C24H24D3FN2O4Cor e Forma:Light YellowPeso molecular:429.5trans-Hydroxy Perhexiline (Mixture of Diastereomers)
CAS:Produto ControladoFórmula:C19H35NOCor e Forma:NeatPeso molecular:293.49N-Isopropyl-2-methyl-2-propyl-3-hydroxypropyl Carbamate
CAS:Produto Controlado<p>Applications An intermediate in the synthesis of Carisoprodol.<br></p>Fórmula:C11H23NO3Cor e Forma:NeatPeso molecular:217.31Ethionamide-d3
CAS:Produto Controlado<p>Applications Ethionamide-d3 is the isotope labelled analogue of Ethionamide (E890420), a antibacterial (tuberculostatic) agent.<br>References Banerjee, A., et al.: Science, 263, 227 (1994), Newton, G., et al.: J. Bacteriol., 178, 1990 (1996), Baulard, A., et al.: J. Biol. Chem., 275, 28326 (2000), Koledin, T., et al.: Arch. Microbiol., 178, 331 (2002), Cardoso, R., et al.: Antimicrob. Agents Chemother., 48, 3373 (2004),<br></p>Fórmula:C8H7D3N2SCor e Forma:NeatPeso molecular:169.265-{4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-benzyl}-thiazolidine-2,4-dione hydrochloride
CAS:Pureza:97.0%Cor e Forma:SolidPeso molecular:392.8999938964844Ref: 10-F036553
1g28,00€5gA consultar10gA consultar25g79,00€50gA consultar100g175,00€250mgA consultarγ-Aminobutyric Acid
CAS:<p>Applications An important inhibitory neurotransmitter. The foods contain γ-aminobutyric acid (GABA) at an amount that shows immediate effect of suppressing autonomic nerve activity related to blood pressure increase. Reacts with isothiocyanates to produce thioureas which have antifungal activity.<br>References Lowry, O., et al.: J. Biol. Chem., 193, 265 (1951), Gerlach, M., et al.: Brain Res., 741, 142 (1996), Choi, D., et al.: J Neurobiol 1992, 23, 1261<br></p>Fórmula:C4H9NO2Cor e Forma:NeatPeso molecular:103.12Defluoro Dolutegravir (>85%)
CAS:<p>Applications Defluoro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.<br>References Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011);<br></p>Fórmula:C20H20FN3O5Pureza:>85%Cor e Forma:NeatPeso molecular:401.39Ilaprazole
CAS:Produto Controlado<p>Applications Ilaprazole is a proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer.<br>References Cao, S., et al.: Acta Pharmacol. Sin., 33, 1095 (2012); Wang, L., et al.: J. Clin. Gastroenterol., 45, 322 (2011)<br></p>Fórmula:C19H18N4O2SCor e Forma:NeatPeso molecular:366.443-Hydroxy-2-pyrone
CAS:Produto Controlado<p>Applications 3-Hydroxy-2-pyrone<br></p>Fórmula:C5H4O3Cor e Forma:NeatPeso molecular:112.084-Fluoro-3-chloroaniline
CAS:Produto Controlado<p>Applications 4-Fluoro-3-chloroaniline, is an organic Fluorinated building block used for the synthesis of pharmaceutical and biologically active compounds such as, novel 6-Fluorobenzothiazole-substituted pyrazole analogues, having antiinflammatory activity.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Reddy, D. R. S., et al.: Pharma Chemica., 5, 207 (2013);<br></p>Fórmula:C6H5ClFNCor e Forma:NeatPeso molecular:145.56Piperonylic Acid
CAS:Produto Controlado<p>Applications Piperonylic Acid is a compound closely mimicking the structure of transcinnamic acid involved in the phenylpropanoid pathway in plant physiology.<br>References Schalk, M. et al.: Plant Physiol., 118, 209 (1998);<br></p>Fórmula:C8H6O4Cor e Forma:NeatPeso molecular:166.132-(piperazin-1-yl)quinazolin-4(3H)-one dihydrochloride
CAS:Pureza:95.0%Peso molecular:303.190002441406251-Phenyl-1,2-propanediol (Mixture of Diastereomers)
CAS:Produto Controlado<p>Applications 1-Phenyl-1,2-propanediol is a reagent in pharmaceutical chemistry, used in the synthesis of nor(pseudo)ephedrine related compounds.<br>References Sehl, T. et al.: Green Chem., 16, 3341 (2014); Moorthy, J. et al.: J. Org. Chem., 76, 9593 (2011);<br></p>Fórmula:C9H12O2Cor e Forma:NeatPeso molecular:152.194-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
CAS:Produto Controlado<p>Applications Sitagliptin intermediate.<br>References Mohri, K., et al.: Chem. Pharm. Bull., 30, 3097 (1982), Cameron, M., et al.: J. Pharm. Biomed. Anal., 28, 137 (2002),<br></p>Fórmula:C16H12F6N4O2Cor e Forma:NeatPeso molecular:406.28Benzyl (3-fluoro-4-morpholinophenyl)carbamate
CAS:Pureza:95.0%Cor e Forma:Liquid, No data available.Peso molecular:330.3590087890625Nitrofurantoin-13C3
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A nitrofuran labelled antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),<br></p>Fórmula:C3C5H6N4O5Cor e Forma:NeatPeso molecular:241.143-Hydroxy Loratadine
CAS:Produto Controlado<p>Applications An intermediate for the preparation of 3-Hydroxy Desloratadine.<br></p>Fórmula:C22H23ClN2O3Cor e Forma:NeatPeso molecular:398.88Apixaban-d3
CAS:Produto Controlado<p>Applications Apixaban-d3 is labelled Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Fórmula:C25H22D3N5O4Cor e Forma:White To Off-WhitePeso molecular:462.52Irbesartan
CAS:Produto Controlado<p>Applications An angiotensin II type 1 (AII1)-receptor antagonist.<br>References Gillis, J.C. and Markham, A.: Drugs, 54, 885 (1997), Chando, T.J., et al.: Drug. Metabol. Dispos., 26, 408 (1998), Massie, B., et al.: New Eng. J. Med., 359, 2456 (2008), Ren, X., et al.: Pharmacol., 83, 80 (2009),<br></p>Fórmula:C25H28N6OCor e Forma:NeatPeso molecular:428.532-Methylpyrazine
CAS:Produto Controlado<p>Applications 2-Methyl-pyrazine is an intermediate used to synthesize 5-Methyl-2(1H)-pyrazinone (M324900) which is a derivative of 2-Hydroxypyrazine (H952710). 2-Hydroxypyrazine (H952710) is used in the synthesis of potential antioxidants.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shi, J. et al.: J. Phys. Org. Chem., 22, 1038 (2009); Bonde, C. et al.: Ind. J. Hetero. Chem., 10, 271 (2001);<br></p>Fórmula:C5H6N2Cor e Forma:NeatPeso molecular:94.11TEMPO
CAS:Produto Controlado<p>Applications TEMPO is a stable radical prepared through the oxidation of 2,2,6,6-tetramethylpiperidine. TEMPO has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy. TEMPO can also be used as a mediator in free radical polymerization.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Seaton, T.A. et al.: Brain Res., 777, 110 (1997); Tanielyan, S.K. et al.: Top. Catal., 55, 556 (2012); Wolinska-Grabczyk, A. et al.: Polymer, 46, 2461 (2005); Keoshkerian, B. et al.: Polym. Prep., 35, 675 (1994);<br></p>Fórmula:C9H18NOCor e Forma:NeatPeso molecular:156.254-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol
CAS:Produto Controlado<p>Applications 4-[(5,6-Diphenyl-2-pyrazinyl)(1-methylethyl)amino]-1-butanol is a diphenylpyrazine derivative which belongs to a class of prostacyclin receptor agonists. It is an impurity of Selexipag (S253150) that is a potential drug for the treatment of various vascular disorders such as pulmonary arterial hypertension and arteriosclerosis obliterans.<br>References Asaki, T., et al.: Bioorg. Med. Chem., 15, 6692 (2007); Kuwano, K., et al.: J. Pharm. Exp. Ther., 322, 1181 (2007);<br></p>Fórmula:C23H27N3OCor e Forma:NeatPeso molecular:361.48N,O-Dibenzoyl-L-tyrosine (>90%)
CAS:Produto Controlado<p>Applications N,O-Dibenzoyl-L-tyrosine is an impurity of Tiropramide (T446900). Tiropramide impurity A.<br>References Fox, S.W., et al.: Arch. Biochem., 25, 13 (1950),<br></p>Fórmula:C23H19NO5Pureza:>90%Cor e Forma:White To Off-WhitePeso molecular:389.43-Hydroxy-4-morpholino-1,2,5-thiazole
CAS:<p>Impurity Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D<br>Applications 3-Hydroxy-4-morpholino-1,2,5-thiazole (Timolol EP Impurity D; Timolol BP Impurity D; Timolol USP Related Compound D) is an intermediate for the preparation of Timolol.<br>References Bodor, N., et al.: J. Med. Chem., 31, 100 (1988),<br></p>Fórmula:C6H9N3O2SCor e Forma:White To Off-WhitePeso molecular:187.221,3-Bis(9H-carbazol-4-yloxy)-2-propanol(Carvedilol Impurity)
CAS:Produto Controlado<p>Applications A carvedilol Impurity.<br></p>Fórmula:C27H22N2O3Cor e Forma:NeatPeso molecular:422.48N-Methylformamide
CAS:Produto Controlado<p>Applications N-Methylformamide is used in amidation or transamidation chemical reactions where formamide is insufficient.<br>References Rao, S. et al.: Org. Lett., 15, 1496 (2013); Xu, K. et al.: Chem. A. Eur. J., 18, 9793 (2012);<br></p>Fórmula:C2H5NOCor e Forma:NeatPeso molecular:59.074-Hydroxy-2-methyl-N-(pyridin-2-yl)-2H-benzo[e][1,2]thiazine-3-carboxamide 1,1-dioxide
CAS:Pureza:95.0%Cor e Forma:Solid, PowderPeso molecular:331.3500061035156Ethyl 5-(naphthalen-1-yl)-1H-pyrazole-4-carboxylate
CAS:Pureza:95.0%Peso molecular:266.29998779296875Ethyl 4[[6-(4-Carbamimidoylphenoxy)hexyl]oxy]benzoate Hydrochloride
<p>Applications Ethyl 4[[6-(4-Carbamimidoylphenoxy)hexyl]oxy]benzoate is an impurity of Hexamidine Diisetionate (H294205), which is an amidine compound used in the treatment of amyloid-related diseases; it is also used as preservative in cosmetics as an antispetic.<br>References Siddall, T., et al.: J. Org. Chem., 31, 3719 (1966)<br></p>Fórmula:C22H28N2O4·HClCor e Forma:NeatPeso molecular:384.47 +(36.46)
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