Derivados de Quinazolina e Quinolina
As quinazolinas e quinolinas são compostos heterocíclicos contendo nitrogénio, com estruturas aromáticas que desempenham um papel fundamental na síntese de fármacos com atividade anticancerígena, antimicrobiana e anti-inflamatória. Os seus derivados apresentam modificações estruturais que otimizam a biodisponibilidade e a seletividade, permitindo o desenvolvimento de novos princípios ativos para diversas aplicações terapêuticas. Estes compostos são utilizados na fabricação de APIs para o tratamento do câncer, infeções, doenças neurodegenerativas e cardiovasculares. Além disso, os derivados de quinazolina e quinolina são essenciais na investigação de inibidores enzimáticos e no desenvolvimento de moléculas bioativas inovadoras.
Na CymitQuimica, oferecemos derivados de quinazolina e quinolina de alta pureza para aplicações em síntese química, desenvolvimento farmacêutico e biotecnologia.
Foram encontrados 65630 produtos de "Derivados de Quinazolina e Quinolina"
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Tazarotene-d8
CAS:Produto Controlado<p>Applications Labelled Tazarotene (T010050). An acetylenic retinoid prodrug converted to the active metabolite, Tazarotenic acid, with selective affinity for retinoic acid receptors RARβ and RARγ. Antiacne; antipsoriatic. Used in treatment of photodamaged skin.<br>References Tang-Liu, D.D.-S., et al.: Clin. Pharmacokinet., 37, 273 (1999), Roeder, A., et al.: Skin Pharmacol. Physiol., 17, 111 (2004),<br></p>Fórmula:C21H13D8NO2SCor e Forma:YellowPeso molecular:359.51a-Desmethyl Anastrozole(>90%)
CAS:Produto Controlado<p>Impurity Anastrozole EP Impurity A<br>Applications α-Desmethyl Anastrozole (Anastrozole EP Impurity A) is an impurity of Anastrozole (A637425) (impurity B).<br></p>Fórmula:C16H17N5Pureza:>90%Cor e Forma:ColourlessPeso molecular:279.341-(4-Chlorophenyl)-5-[6-[[4-[(4-chlorophenyl)amino]-6-[(1S,2R,3R,4R)-1,2,3,4,5-pentahydroxypentyl]-1,3,5-triazin-2-yl]amino]hexyl]biguanide D-Gluconic Acid
CAS:Produto ControladoFórmula:C28H38Cl2N10O5•C6H12O7Cor e Forma:NeatPeso molecular:665.57196161-(2,3-dimethyl-1H-indol-1-yl)-3-(3,5-dimethyl-1H-pyrazol-1-yl)propan-2-ol
CAS:Pureza:95.0%Peso molecular:297.4020080566406[3-[[[2-(Diaminomethyleneamino)-4-thiazolyl]methyl]thio]propionyl]sulfamide Hydrochloride
CAS:Produto Controlado<p>Impurity Famotidine EP Impurity C<br>Applications An intermediate in the synthesis of the metabolite of the drug Famotidine.<br>References Yanagisawa, I., et al.: J. Med. Chem., 30, 1787 (1987), Singh, S., et al.: J. Pharm. Sci., 91, 253 (2002),<br></p>Fórmula:C8H14N6O3S3·ClHCor e Forma:Off-WhitePeso molecular:374.89Moclobemide
CAS:Produto Controlado<p>Applications A reversible monoamine oxidase inhibitor.<br>References Wiesel, F.A., et al.: Eur. J. Clin. Pharmacol., 28, 89 (1985), Burkard, W.P., et al.: J. Pharmacol. Exp. Ther., 248, 391 (1989)<br></p>Fórmula:C13H17ClN2O2Cor e Forma:WhitePeso molecular:268.74Gefitinib-d6
CAS:Produto Controlado<p>Applications Gefitinib-d6 is the labeled version of Gefitinib (G304000), which is an antineoplastic.<br>References Anderson, N.G., et al.: Int. J. Cancer, 94, 774 (2001), Hirata, A., et al.: Cancer Res., 62, 2554 (2002), Kris, M.G., et al.: J. Am. Med. Assoc., 290, 2149 (2003), Tamura, K., et al.: Expert Opin. Pharmacother., 6, 985 (2005)<br></p>Fórmula:C22D6H18ClFN4O3Cor e Forma:NeatPeso molecular:452.939rac-Talinolol
CAS:Produto Controlado<p>Applications Selective β1-adrenergic blocker structurally related to Practolol. Antihypertensive; antiarrhythmic.<br>References Assmann, I., et al.: Curr. Med. Res. Opin., 13, 325 (1995), Trausch, B., et al.: Biopharm. Drug Dispos., 16, 403 (1995),<br></p>Fórmula:C20H33N3O3Cor e Forma:White To Light PinkPeso molecular:363.49Levofloxacin Carboxylic Acid (Levofloxacin Difluoro Impurity)
CAS:Produto Controlado<p>Impurity Levofloxacin USP Related Compound B<br>Applications Levofloxacin intermediate.<br>References Liu, Bo; Y., et al.: Bioorg. Med. Chem., 13, 2451 (2005), Lalitha D., et al.: J. Pharm. Biomed. Anal., 50, 710 (2009),<br></p>Fórmula:C13H9F2NO4Cor e Forma:NeatPeso molecular:281.21[1,1'-Biphenyl]-4-yl(phenyl)methanol
CAS:Produto Controlado<p>Impurity Bifonazole EP Impurity A<br>Applications [1,1'-Biphenyl]-4-yl(phenyl)methanol (Bifonazole EP Impurity A) is a Bifonazole (B383400), an anti-fungal agent used in the treatment of skin diseases. Causes an increase in Ca2+ concentration and triggers cell death in PC3 human prostate cancer cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Cheng, J. et al.: J. Recep. Sign. Transduct., 34, 493 (2014); Chen, Z. et al.: Mol. Pharm., 12, 590 (2015);<br></p>Fórmula:C19H16OCor e Forma:NeatPeso molecular:260.33Domperidone N-Oxide
CAS:Produto Controlado<p>Impurity Domperidone EP Impurity C<br>Stability Hygroscopic<br>Applications Domperidone N-Oxide (Domperidone EP Impurity C) is an oxygenated metabolite of the gastrokinetic and antinauseant drug Domperidone (D531100).<br>References Van Vaeck, L. et al.: Biomed. Env. Mass Spec., 16, 121 (1988);<br></p>Fórmula:C22H24ClN5O3Cor e Forma:White To Off-WhitePeso molecular:441.91(R)-3-Chloro-1-phenyl-1-(2-methylphenoxy)propane
CAS:Produto ControladoFórmula:C16H17ClOCor e Forma:NeatPeso molecular:260.76Apixaban Dimer
CAS:Produto Controlado<p>Applications Apixaban Dimer is an impurity compound of Apixaban (A726700). Apixaban is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful in the prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J. M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Fórmula:C40H34N10O6Cor e Forma:NeatPeso molecular:750.78Terbufoxon Sulfoxide
CAS:Produto Controlado<p>Applications Terbufoxon Sulfoxide is a metabolite of Terbufoxon (T109075), a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rahman, Md. M. et al.: Food Chem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008); Polgar, L. et al.: J. Chrom. A., 1249, 83 (2012);<br></p>Fórmula:C9H21O4PS2Cor e Forma:NeatPeso molecular:288.36Isoproturon
CAS:Produto Controlado<p>Applications Pre-and post-emergence herbicide for control of annual grasses and broad-leaved weeds. Herbicide.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fournier, J.-C., et al.: Chemosphere, 4, 207 (1975), Gonzales, P., et al.: Weed Res., 23, 39 (1983),<br></p>Fórmula:C12H18N2OCor e Forma:Off-WhitePeso molecular:206.28(E)-3-(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)acrylaldehyde
CAS:Pureza:95%Peso molecular:317.3630065917969Ethyl Difluoroacetate
CAS:Produto Controlado<p>Applications Ethyl difluoroacetate<br></p>Fórmula:C4H6F2O2Cor e Forma:NeatPeso molecular:124.091-(5-Benzyl-thiophen-2-yl)-ethanone
CAS:Fórmula:C13H12OSPureza:97%Cor e Forma:LiquidPeso molecular:216.3Ethyl 2,4-dichloroquinazoline-6-carboxylate
CAS:Fórmula:C11H8Cl2N2O2Pureza:95%Cor e Forma:SolidPeso molecular:271.12,3-Di-furan-2-yl-quinoxaline-6-carboxylic acid
CAS:Cor e Forma:SolidPeso molecular:306.2770080566406Prochlorperazine Edisylate
CAS:Produto ControladoFórmula:C20H24ClN3S·C2H6O6S2Cor e Forma:NeatPeso molecular:564.14N-Nitroso Iminostilbene
CAS:Produto Controlado<p>Applications N-Nitroso Iminostilbene is derived from Iminostilbene (I445000), which is a metabolite of Carbamazepine (CBZ) (C175840).<br>References Lertratanangkoon, K., et al.: Drug Metab. Dispos., 10, 1 (1982), Deleu, D., et al.: Eur. J. Clin. Pharmacol., 57, 243 (2001)<br></p>Fórmula:C14H10N2OCor e Forma:NeatPeso molecular:222.24Decarbonyl Rivaroxaban
CAS:<p>Applications Decarbonyl Rivaroxaban is an impurity of Rivaroxaban (R538000), which is a novel antithrombotic agent. A highly potent and selective, direct FXa inhibitor.<br>References Ansell, J., et al.: Drugs, 64, 1 (2004), Eriksson, B., et al.: J. Thromb. Haemost., 3, 103 (2005), Kubitza, D., et al.: Clin. Pharmacol. Ther., 78, 412 (2005),<br></p>Fórmula:C18H20ClN3O4SCor e Forma:White To Off-WhitePeso molecular:409.891-Benzyl-3-(2,4-dimethylphenyl)-1H-pyrazole-5-carboxylic acid
Pureza:95.0%Peso molecular:306.3649902343752-(4-methoxyphenyl)-8-methylquinoline-4-carboxylic acid
CAS:Pureza:95.0%Peso molecular:293.3219909667969Desmethyl Ofloxacin
CAS:Produto Controlado<p>Impurity Ofloxacin EP Impurity E<br>Applications Desmethyl Ofloxacin (Ofloxacin EP Impurity E) is a metabolite of Ofoxacin (O245750), a fluorinated quinolone antibacterial.<br>References Leysen, D., et al.: Antimicrob. Agents Chemother., 33, 1 (1989); Polk, R., et al.: J. Antimicrob. Chemother., 27, 17 (1991); Todo, Y., et al.: Chem. Pharm. Bull., 42, 2049 (1994); Furuhata, K., et al.: Biol. Pharm. Bull., 21, 456 (1998); Monk, J.P., et al.: Drugs, 33, 346 (1987); Drlica, K., Curr. Opin. Microbiol. 2, 504 (1990)<br></p>Fórmula:C17H18FN3O4Cor e Forma:White To Light BeigePeso molecular:347.341-Chloro-2-nitrobenzene
CAS:Produto Controlado<p>Applications 1-Chloro-2-nitrobenzene is a useful synthetic intermediate. It was used in the synthesis of 1-hydroxybenzotriazole derivatives. Reaction of 1-chloro-2-nitrobenzene with dinitrogen pentoxide in dichloromethane is strongly catalysed by H-Faujasite-720.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Fathalla, M., et al.: J. Chem. Soc. Pak., 33, 324 (2011); Claridge, R., et al.: J. Chem. Soc. Perkin Trans. II, 9, 1815, (1999)<br></p>Fórmula:C6H4ClNO2Cor e Forma:NeatPeso molecular:157.55Thioridazine-d3 2-Sulfone
CAS:Produto Controlado<p>Applications A labelled metabolite of Thioridazine (THD 2-SO2).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Niedzwiecki, D., et al.: J. Pharmacol. Exp. Ther., 250, 126 (1989), Eap, C., et al.: Ther. Drug Monit., 13, 356 (1991), Shah, P., et al.: J. Pharm. Sci., 81, 309 (1992), Eap, C., et al.: J. Pharm. Biomed. Anal., 11, 451 (1993), Blake, B., et al.: Xenobiotica, 25, 337 (1995),<br></p>Fórmula:C21H23D3N2O2S2Cor e Forma:NeatPeso molecular:405.59Marbofloxacin-d8
CAS:Produto Controlado<p>Applications Labelled fluorinated quinolone antibacterial.<br>References Gruet, P., et al.: Vet. Rec., 140, 199 (1977), Lefebvre, H.P., et al.: J. Vet. Pharmacol. Ther., 21, 453 (1998),<br></p>Fórmula:C172H8H11FN4O4Cor e Forma:NeatPeso molecular:370.40Nitrofurantoin
CAS:Produto Controlado<p>Applications A nitrofuran antibiotic with low resistance potential that is rapidly metabolized by mammals. Active against both Gram-positive and Gram-negative bacteria. Nitrofurantoin is also a prooxidant that is cytotoxic due to the generation of intracellular H2O2. Antibacterial.Environmental contaminants; Food contaminants; Heat processing contaminants<br>References Cadwallader, D.E., et al.: Anal. Profiles Drug Subs., 5, 345 (1976), Rogers, R.G., et al.: Am. J. Obstr. Gynecol., 191, 182 (2004),<br></p>Fórmula:C8H6N4O5Cor e Forma:Light Yellow To YellowPeso molecular:238.16Ipragliflozin
CAS:Produto Controlado<p>Applications Ipragliflozin is a potent and selective inhibitor of sodium-glucose cotransporter-2 (SGLT2) and can serve as a potential agent for the treatment of type 1 and type 2 diabetes.<br>References Kadokura, T., et al.: Clin. Pharmacokinet., 53, 975 (2014); Kashiwagi, A., et al.: J. Diabetes Investig., 5, 382 (2014); Tahara, A., et al.: J. Pharm. Pharmacol., 66, 975 (2014); Zhang, W., et al.: Clin. Drug Invest., 33, 489 (2013)<br></p>Fórmula:C21H21FO5SCor e Forma:WhitePeso molecular:404.45Thiazolylmethyl-4-nitrophenylcarbonate
CAS:Produto Controlado<p>Applications Retinovir intermediate.<br>References Randad, R., et al.: Bioorg. Med. Chem. Lett., 4, 1247 (1994), Scholz, et al.: J. Med. Chem., 37, 3079 (1994), Vacca, J., et al.: Bioorg. Med. Chem. Lett., 4, 499 (1994),<br></p>Fórmula:C11H8N2O5SCor e Forma:Light YellowPeso molecular:280.26Desethylene Aripiprazole
CAS:<p>Impurity Aripiprazole Desethylene Impurity<br>Applications Desethylene Aripiprazole is an Aripiprazole derivative. Aripiprazole Desethylene Impurity<br></p>Fórmula:C21H25Cl2N3O2Cor e Forma:NeatPeso molecular:422.35(R)-(+)-Thalidomide
CAS:Produto Controlado<p>Applications Optically active isomer of Thalidomide, which inhibits FGF-induced angiogenesis. Inhibits replication of human immunodeficiency virus type 1. Teratogenic sedative.<br>References D’Amato, r.J., et al.: Proc. Natl. Acad. Sci. USA, 91, 4082 (1994), Makonkawkeyoon, S., et al.: Proc. Natl. Acad. Sci. USA, 90, 5974 (1993), Schumacher, H., et al.: J. Pharmacol. Exp. Therap., 160, 189 (1968)<br></p>Fórmula:C13H10N2O4Cor e Forma:NeatPeso molecular:258.231,2,4-Triazol-4-amine
CAS:Produto Controlado<p>Applications 1,2,4-Triazol-4-amine is an intermediate used to prepare potent, selective, and orally active cyclooxygenase-2 inhibitors. It is also used to synthesize hydroxyphenacyl azoles and related azolium derivatives as antifungal agents.<br>References Song, Y., et al.: J. Med. Chem., 42, 1151 (1999); Emami, S., et al.: Bioorg. Med. Chem. Lett., 18. 141 (2008)<br></p>Fórmula:C2H4N4Cor e Forma:NeatPeso molecular:84.082-Azahypoxanthine Sodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 2-Azahypoxanthine is a major degradation product of Dacarbazine (D101400). 2-Azahypoxanthine is possibly linked with some adverse effects of Dacarbazine (D101400). AHX is a natural product that is produced by fungi that spurs the growth of grass.<br>References Baird, G., et al.: Lancet, 2, 681 (1978), Horton, J., et al.: J. Pharm. Pharmacol., 33, 808 (1981), Shetty, B., et al.: J. Pharm. Biomed. Anal., 10, 675 (1992); Chem. and Eng. News p.7 Oct.1, (2018)<br></p>Fórmula:C4H2N5NaOCor e Forma:NeatPeso molecular:159.08Relcovaptan
CAS:<p>Stability Hygroscopic<br>Applications Relcovaptan is a selective vasopressin-1a receptor antagonist that prevents cellular swelling and provides treatment for post-traumatic brain edema.<br>References Marmarou, C.R., et. al.: Brain Res., 1581, 89 (2014)<br></p>Fórmula:C28H27Cl2N3O7SCor e Forma:NeatPeso molecular:620.50Aripiprazole Dimer
CAS:Produto Controlado<p>Impurity Aripiprazole EP Impurity G<br>Applications Aripiprazole Dimer is an impurity of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity. Aripiprazole EP Impurity G<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998); Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998);<br></p>Fórmula:C48H56Cl4N6O4Cor e Forma:WhitePeso molecular:922.81N-Cyano-N’-[2-[(4-methyl-5-imidazolyl)methylthio]ethyl]-S-methylisothiourea
CAS:Produto ControladoFórmula:C10H15N5S2Cor e Forma:NeatPeso molecular:269.39Risperidone-d4
CAS:Produto Controlado<p>Applications A deuterated version of Risperidone (R525000), a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)<br></p>Fórmula:C232H4H23FN4O2Cor e Forma:BeigePeso molecular:414.51Haloperidol
CAS:Produto Controlado<p>Applications Antidyskinetic; antipsychotic. Neuroprotective product.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Janicki, C.A., et al.: Anal. Profiles Drug Subs., 9, 341 (1980), Beresford, R., et al.: Drugs, 33, 31 (1987)<br></p>Fórmula:C21H23ClFNO2Cor e Forma:Off-WhitePeso molecular:375.86α-(4-Chlorophenyl)-α-propionylacetonitrile
CAS:Produto Controlado<p>Applications Pyrimethamine intermediate.<br>References Takayama, K., et al.: Antimicrob. Agents Chemother., 33, 1493 (1989), Robson, C., et al.: J. Med. Chem., 40, 3040 (1997), Horton, J., et al.: J. Mol. Biol., 353, 334 (2005), Horton, J., et al.: J. Mol. Biol., 353, 334 (2005), Janin, Y., et al.: Bioorg. Med. Chem., 15, 2479 (2007),<br></p>Fórmula:C11H10ClNOCor e Forma:White To BrownPeso molecular:207.66Ethyl 2-(2-(4-methoxyphenoxy)acetamido)-4-methyl-5-(phenylcarbamoyl)thiophene-3-carboxylate
CAS:Pureza:98%Peso molecular:468.5199890136719MEK 162
CAS:Produto Controlado<p>Applications MEK 162 is a MEK1/2 inhibitor allowing it to be a effective anti-cancer medication.<br>References Kopetz,S., et al.: N. Engl., 381, 1632-1643<br></p>Fórmula:C17H15BrF2N4O3Cor e Forma:NeatPeso molecular:441.232-Benzylacrylic Acid
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications 2-Benzylacrylic Acid (cas# 5669-19-2) is a compound useful in organic synthesis.<br></p>Fórmula:C10H10O2Cor e Forma:NeatPeso molecular:162.192-Nitrobenzotrifluoride
CAS:Produto Controlado<p>Applications 2-Nitrobenzotrifluoride can be used for self-repairing polyimide based on dynamic imine bond.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lei, X., et.al., Faming Zhuanli Shenqing, 15, (2019);<br></p>Fórmula:C7H4F3NO2Cor e Forma:NeatPeso molecular:191.107rac Naproxen-d3
CAS:Produto Controlado<p>Applications Labelled Naproxen. An anti-inflammatory, analgesic, antipyretic. A non-steroidal anti-inflammatory.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harrison, I.T., et al.: J. Med. Chem., 13, 203 (1970)<br></p>Fórmula:C142H3H11O3Cor e Forma:Off-WhitePeso molecular:233.28N-Formyl Apixaban
CAS:Produto Controlado<p>Applications N-Formyl Apixaban is derived from Apixaban (A726700) which is a potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.<br>References Luettgen, J.M. et al.: J. Enz. Inhib. Med. Chem., 26, 514 (2011); Glanis, T. et al.: J. Thromb. Thrombol., 31, 310 (2011); barrett, Y.C. et al.: Thromb. Haemos., 105, 181 (2011);<br></p>Fórmula:C26H25N5O5Cor e Forma:NeatPeso molecular:487.51(2E)-1-{[1,1'-biphenyl]-4-yl}-3-(thiophen-2-yl)prop-2-en-1-one
CAS:Pureza:95.0%Peso molecular:290.3800048828125Terbufoxon Sulfone
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications Terbufoxon Sulfone is a metabolite of Terbufoxon (T109075), a pesticide used in the protection of fruit and vegetable crops against insects. Acetylcholinesterase inhibitor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Rahman, Md. M. et al.: Food CHem., 133, 604 (2012); Stojan, J. et al.: Biochem., 5599 (2008);<br></p>Fórmula:C9H21O5PS2Cor e Forma:NeatPeso molecular:304.36Pseudo Vardenafil
CAS:<p>Applications Vardenafil analog.<br>References Blok-Tip, L., et al.: Food Addit. Contam., 21, 737 (2004), Reffelmann, T., et al.: Curr. Pharm. Des., 12, 3485 (2006), Reepmeyer, J., et al.: J. Pharm. Biomed. Anal., 43, 1615 (2007),<br></p>Fórmula:C22H29N5O4SCor e Forma:NeatPeso molecular:459.565-(Dimethylaminomethyl)-2-furfuryl Alcohol Hydrochloride
CAS:Produto Controlado<p>Impurity Ranitidine EP Impurity F<br>Stability Hygroscopic<br>Applications 5-(Dimethylaminomethyl)-2-furfuryl Alcohol Hydrochloride (Ranitidine EP Impurity F) is an intermediate in the synthesis of Ranitidine hydrochloride (R120000).<br>References Salameh, A., et al.: J. Food Sci., 71, 10 (2006), Guerrieri, P., et al.: Pharm. Res., 24, 147 (2007),<br></p>Fórmula:C8H13NO2·ClHCor e Forma:BrownPeso molecular:191.66Methyl 3-(3-carbamoyl-4-(3-methoxyphenylamino)-8-methylquinolin-6-ylsulfonyl)benzoate
CAS:Pureza:98%Peso molecular:505.549987792968753-(4-CHLOROPHENYL)-1-PHENYL-1H-PYRAZOLE-4-CARBALDEHYDE
CAS:Pureza:95.0%Peso molecular:282.7300109863281Darunavir
CAS:<p>Applications Second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.<br>References Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),<br></p>Fórmula:C27H37N3O7SCor e Forma:BeigePeso molecular:547.66N-[2-(3,4-Dihydro-1-oxo-2(1H)-isoquinolinyl)-2-oxoethyl]-N-formyl-cyclohexanecarboxamide
CAS:Produto Controlado<p>Impurity Praziquantel USP Related Compound C<br>Applications N-[2-(3,4-Dihydro-1-oxo-v2(1H)-isoquinolinyl)-2-oxoethyl]-N-formyl-cyclohexanecarboxamide is a compound related to Praziquantel (P702095),effective against flatworms. Praziquantel USP Related Compound C.<br>References Kuhn, I., et al.: Bioorg. Med. Chem., 18, 7900 (2010), Wang, W., et al.: Parasitol., 137, 1905 (2010),<br></p>Fórmula:C19H22N2O4Cor e Forma:NeatPeso molecular:342.39FOY 251
CAS:<p>Applications A metabolite of Camostat. It is a pollen protease inhibitor for prevention and control of allergy.<br>References Senochuki, K., et al.: J. Med. Chem., 38, 2521 (1995)<br></p>Fórmula:C16H15N3O4·CH4O3SCor e Forma:White SolidPeso molecular:409.41METHYL 2-((6-ISOPROPYL-2-OXO-1-PHENYL-1,2-DIHYDROPYRIDIN-4-YL)AMINO)BENZOATE
CAS:Pureza:95.0%Peso molecular:362.4289855957031[3-methoxy-4-(2-morpholin-4-yl-2-oxoethoxy)phenyl]amine hydrobromide
CAS:Fórmula:C13H19BrN2O4Cor e Forma:Beige powderPeso molecular:347.209Apatinib
CAS:Produto Controlado<p>Applications Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mi, Y. et al.: Cancer Res., 70, 7981 (2010); Tong, X.Z. et al.: Biochem. Pharmacol., 83, 586 (2012); Ding, J, et al.: J. Chrom B Anal. Technol. Biomed. Life Sci., 895, 108 (2012);<br></p>Fórmula:C24H23N5O·CH4O3SCor e Forma:NeatPeso molecular:493.58Thioridazine-d3 Hydrochloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Dopamine receptor blocker; parent compound of sulforidazine and mesoridazine. Antipsychotic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Goldenthal, E.I., Toxicol. Appl. Pharmacol., 18, 185 (1971), Abdel-Moety, E.M., et al.: Anal. Profile Drug Subs., 18, 459 (1989),<br></p>Fórmula:C21D3H23N2S2·ClHCor e Forma:NeatPeso molecular:410.05Kynurenic Acid
CAS:<p>Applications A product of L-Tryptophan metabolism, possessing neruoactive activity having antiexcitotoxic and anticonvulsant properties.<br>References Wejksza, K., et al.: Pharmacol. Rep., 61, 751 (2009), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010), Di Natale, B., et al.: Toxicol. Sci., 115, 89 (2010),<br></p>Fórmula:C10H7NO3Cor e Forma:NeatPeso molecular:189.173,4-Dehydro Cilostazol
CAS:Produto Controlado<p>Impurity Cilostazol USP Related Compound B<br>Applications A metabolite of Cilostazol.<br></p>Fórmula:C20H25N5O2Cor e Forma:Off WhitePeso molecular:367.444-(4-Nitrophenyl)-3-morpholinone
CAS:Produto ControladoFórmula:C10H10N2O4Cor e Forma:NeatPeso molecular:222.203-[2-[4-(4-Fluoro-2-hydroxybenzoyl)-1-piperidinyl]ethyl]-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one Hydrochloride
CAS:Produto Controlado<p>Applications Risperidone (R525000) metabolite.<br>References Meuldermans, W. et al.; Drug Metab. Dispos. 22, 129 (1994); Mannens, G. et al.; Drug Metab. Dispos. 21, 1134 (1993)<br></p>Fórmula:C23H28FN3O3·HClCor e Forma:NeatPeso molecular:449.946Ethyl 2-Chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate
CAS:Produto Controlado<p>Applications Ethyl 2-chloro-2-(2-(4-methoxyphenyl)hydrazono)acetate (cas# 27143-07-3) is a useful research chemical.<br></p>Fórmula:C11H13N2O3ClCor e Forma:NeatPeso molecular:256.68Valsartan Benzyl Ester
CAS:<p>Impurity Valsartan USP Related Compound C<br>Applications Valsartan (V095750) intermediate. Valsartan USP Related Compound C.<br>References Cramer., et al.: J. Med. Chem., 42, 3919 (1999),<br></p>Fórmula:C31H35N5O3Cor e Forma:NeatPeso molecular:525.64Xanthurenic Acid
CAS:<p>Applications Excreted by pyridoxine-deficient animals after the ingestion of tryptophan.<br>References Aquilina, J., et al.: Biochemistry, 39, 16176 (2000), Roberts, J., et al.: Photochem. Photobiol., 74, 740 (2001),<br></p>Fórmula:C10H7NO4Cor e Forma:NeatPeso molecular:205.17Etoricoxib-d3
CAS:Produto Controlado<p>Applications A specific inhibitor of COX-2 .<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References McGeer, P.L., et al.: Exp. Gerontol., 37, 925 (2002), Chenevard, R., et al.: Circulation, 107, 405 (2003)<br></p>Fórmula:C182H3H12ClN2O2SCor e Forma:NeatPeso molecular:361.86ABT 199 (Venetoclax)
CAS:Produto Controlado<p>Applications ABT 199 is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.<br>References Davids, M. & Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013);<br></p>Fórmula:C45H50ClN7O7SCor e Forma:Light Yellow To YellowPeso molecular:868.44Apalutamide
CAS:Produto Controlado<p>Applications Apalutamide is a second-generation antiandrogen used in the treatment of prostate cancer.<br>References Li, Huifang, et al.: J. of Chem. Info. and Model., 53(1), 123-130 (2013);Joseph, James D., et al.: Cancer Disc., 3(9), 1020-1029 (2013)<br></p>Fórmula:C21H15F4N5O2SCor e Forma:White To Off-WhitePeso molecular:477.43472-(Diphenylmethoxy)-N-methylethylamine
CAS:Produto Controlado<p>Applications 2-(Diphenylmethoxy)-N-methylethylamine is used in the pereparation of H1 and H2 receptor antagonists containing Diphenhydramine (D486900) derivatives. Diphenhydramine is a H1-histamine receptor antagonist. Diphenhydramine (D486900) is categorized as an antihistaminic; sedative, hypnotic.<br>References Wolf, C. et al.: Archiv. de Pharm., 329, 87 (1996); Gruhzit, O.M., et al.: J. Pharmacol. Exp. Ther., 89, 227 (1947), Holcomb, I.J., et al.: Anal. Profiles Drug Subs., 3, 173 (1974), Scavone, J.M., et al.: J. Clin. Pharmacol., 38, 603 (1998),<br></p>Fórmula:C16H19NOCor e Forma:Light Yellow To YellowPeso molecular:241.33Aripiprazole-d8
CAS:Produto Controlado<p>Applications Aripiprazole-d8 is a deuterated version of Aripiprazole (A771000), a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.<br>References Canive, J.M., et al.: Psychopharmacol. Bull., 34, 101 (1998), Oshiro, Y., et al.: J. Med. Chem., 41, 658 (1998),<br></p>Fórmula:C232H8H19Cl2N3O2Cor e Forma:Off White SolidPeso molecular:456.432-(5-Amino-3-phenylpyrazol-1-yl)ethanol
CAS:Pureza:95.0%Cor e Forma:Solid, Off-white solidPeso molecular:203.2449951171875(S) FTY720 Phosphate
CAS:<p>Applications FTY720 is a sphingosine 1-phosphate receptor modular, ameliorates experimental autoimmune encephalomyelitis by inhibition of T cell infiltration. FTY720 Phosphate is the active metabolite of FTY720-phosphate.<br>References Chiba, K., et al.: J. Immunol., 160, 5037 (1998), Brinkmann, V., et al.: J. Biol. Chem., 277, 21453 (2002), Kiuchi, M., et al.: Bioorganic & Medicinal Chemistry, 13, 425 (2005<br></p>Fórmula:C19H34NO5PCor e Forma:WhitePeso molecular:387.45Valsartan
CAS:<p>Stability Hygroscopic<br>Applications A nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.<br>References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)<br></p>Fórmula:C24H29N5O3Cor e Forma:NeatPeso molecular:435.52Palbociclib-d4
CAS:Produto Controlado<p>Applications Palbociclib-d4 is an isotope labelled compound of Palbociclib (P139900). Palbociclib (P139900) is an experimental drug for the treatment of breast cancer being developed by Pfizer. It is a selective inhibitor of the cyclin-dependent kinases CDK4 and CDK6.<br>References Finn, R., et al.: Breast Cancer Res., 11, 5 (2009)<br></p>Fórmula:C24H25D4N7O2Cor e Forma:Light YellowPeso molecular:451.56(R)-Rabeprazole Sodium Salt
CAS:Produto Controlado<p>Applications A partially reversible gastric proton pump inhibitor.<br>References Moda, T., et al.: Lett. Drug Des. Discov., 4, 502 (2007), Belaz, K., et al.: J. Pharm. Biomed. Anal., 47, 81 (2008),<br></p>Fórmula:C18H20N3NaO3SCor e Forma:NeatPeso molecular:381.423-(1-Benzyl-4-hydroxypiperidin-4-yl)-2-chloroquinoline
CAS:Pureza:98%Peso molecular:352.85998535156254-((2R,3S,6S)-6-(4-Fluorophenyl)-3-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenol (Ezetimibe Impurity)
<p>Applications 4-((2R,3S,6S)-6-(4-Fluorophenyl)-3-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)phenol, is a diol impurity of Ezetimibe (E975000), a drug that lowers plasma cholesterol levels.<br>References van Heek, M., at al.: J. Pharmacol. Exp. Ther., 283, 157 (1997), van Heek, M., at al.: Brit. J. Pharmacol., 129, 1748 (2000)<br></p>Fórmula:C18H19FO3Cor e Forma:NeatPeso molecular:302.346-methoxy-N-(pyridin-3-ylmethyl)-1,3-benzothiazol-2-amine
CAS:Pureza:95.0%Peso molecular:271.3399963378906
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